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Tytuł:
Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells.
Autorzy:
Wei X; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Chow HY; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Chong HC; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Leung SL; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Ho MK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Lee MY; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.; Lo Ka Chung Research Centre for Natural Anti-Cancer Drug Development, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Leung YC; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.; Lo Ka Chung Research Centre for Natural Anti-Cancer Drug Development, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 06; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
Agmatine*
Colonic Neoplasms*
Humans ; Animals ; Rats ; Arginase ; Arginine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Humans decompose tasks by trading off utility and computational cost.
Autorzy:
Correa CG; Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.
Ho MK; Department of Psychology, Princeton University, Princeton, New Jersey, United States of America.; Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America.
Callaway F; Department of Psychology, Princeton University, Princeton, New Jersey, United States of America.
Daw ND; Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.; Department of Psychology, Princeton University, Princeton, New Jersey, United States of America.
Griffiths TL; Department of Psychology, Princeton University, Princeton, New Jersey, United States of America.; Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Jun 01; Vol. 19 (6), pp. e1011087. Date of Electronic Publication: 2023 Jun 01 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Heuristics*
Humans ; Goals ; Behavior
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Precise Sn-Doping Modulation for Optimizing CdWO 4 Nanorod Photoluminescence.
Autorzy:
Manjunatha K; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Ho MK; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Hsu TE; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Chiu HH; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Li TY; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.; National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan.
Kumar BV; Department of Chemistry, University College of Science, Osmania University, Hyderabad 500007, Telangana, India.
Reddy PM; Department of Chemistry, University College of Science, Osmania University, Hyderabad 500007, Telangana, India.
Chan TS; National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan.
Wu YH; National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan.; Department of Material Science and Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Lin BH; National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan.
Karmenyan A; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Cheng CL; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
Gandhi AC; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.; Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Wu SY; Department of Physics, National Dong Hwa University, Hualien 97401, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 01; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cadmium*
Nanotubes*
Luminescence ; X-Ray Diffraction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
On enhancing interprofessional education: A student perspective.
Autorzy:
Ho MK; Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong SAR.
Tian E; Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong SAR.
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Źródło:
Medical teacher [Med Teach] 2022 Feb; Vol. 44 (2), pp. 218. Date of Electronic Publication: 2021 May 10.
Typ publikacji:
Letter
MeSH Terms:
Interprofessional Education*
Interprofessional Relations*
Humans ; Students
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The association between trajectories of risk factors and risk of cardiovascular disease or mortality among patients with diabetes or hypertension: A systematic review.
Autorzy:
Wang Y; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Wan EYF; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Laboratory of Data Discovery for Health (D24H), Hong Kong Science and Technology Park, Sha Tin, Hong Kong SAR, China.
Mak IL; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Ho MK; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Chin WY; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Yu EYT; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Lam CLK; Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
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Źródło:
PloS one [PLoS One] 2022 Jan 27; Vol. 17 (1), pp. e0262885. Date of Electronic Publication: 2022 Jan 27 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:
Blood Pressure*
Diabetes Complications*/blood
Diabetes Complications*/mortality
Diabetes Complications*/physiopathology
Glomerular Filtration Rate*
Hypertension*/blood
Hypertension*/etiology
Hypertension*/mortality
Hypertension*/physiopathology
Glycated Hemoglobin/*metabolism
Lipids/*blood
Humans ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Plastic and reconstructive surgery during the COVID-19 pandemic: impacts on healthcare workers, financing, and governance.
Autorzy:
Ho MK; Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Chau CYC; Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
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Źródło:
Archives of plastic surgery [Arch Plast Surg] 2022 Jan; Vol. 49 (1), pp. 127-129. Date of Electronic Publication: 2022 Jan 15.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Plastic surgery education in the COVID-19 pandemic: hindrance or opportunity?
Autorzy:
Chau CYC; Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
Ho MK; Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
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Źródło:
Archives of plastic surgery [Arch Plast Surg] 2021 Nov; Vol. 48 (6), pp. 717-719. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of continuity of care on health outcomes among patients with diabetes mellitus and/or hypertension: a systematic review.
Autorzy:
Chan KS; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
Wan EY; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China. .; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China. .
Chin WY; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
Cheng WH; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
Ho MK; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
Yu EY; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
Lam CL; Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong, China.
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Źródło:
BMC family practice [BMC Fam Pract] 2021 Jul 03; Vol. 22 (1), pp. 145. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:
Diabetes Mellitus*/epidemiology
Diabetes Mellitus*/therapy
Hypertension*/epidemiology
Hypertension*/therapy
Adult ; Continuity of Patient Care ; Health Services ; Humans ; Outcome Assessment, Health Care
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss.
Autorzy:
Lavinsky J
Crow AL
Pan C
Wang J
Aaron KA
Ho MK
Li Q
Salehide P
Myint A
Monges-Hernadez M
Eskin E
Allayee H
Lusis AJ
Friedman RA
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Źródło:
PLoS genetics [PLoS Genet] 2015 Jun 11; Vol. 11 (6), pp. e1005293. Date of Electronic Publication: 2015 Jun 11 (Print Publication: 2015).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss.
Autorzy:
Lavinsky J; Graduate Program in Surgical Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Crow AL; Department of Preventive Medicine and Institute for Genetic Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Pan C; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.
Wang J; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Aaron KA; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Ho MK; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Li Q; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Salehide P; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Myint A; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Monges-Hernadez M; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Eskin E; Department of Computer Science, University of California, Los Angeles, Los Angeles, California, United States of America.
Allayee H; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.
Lusis AJ; Department of Preventive Medicine and Institute for Genetic Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.
Friedman RA; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2015 Apr 16; Vol. 11 (4), pp. e1005094. Date of Electronic Publication: 2015 Apr 16 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Hearing Loss, Noise-Induced/*genetics
NADPH Oxidases/*genetics
Animals ; Evoked Potentials, Auditory ; Genome-Wide Association Study ; Hearing Loss, Noise-Induced/physiopathology ; Heterozygote ; Mice ; Mice, Inbred C57BL ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Synthesis and functional characterization of substituted isoquinolinones as MT2-selective melatoninergic ligands.
Autorzy:
Hu Y; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
Chan KH; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
He X; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
Ho MK; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
Wong YH; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong; State Key Laboratory of Molecular Neuroscience, and the Molecular Neuroscience Center, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
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Źródło:
PloS one [PLoS One] 2014 Dec 05; Vol. 9 (12), pp. e113638. Date of Electronic Publication: 2014 Dec 05 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Structure-Activity Relationship*
Isoquinolines/*chemistry
Melatonin/*metabolism
Receptor, Melatonin, MT1/*metabolism
Receptor, Melatonin, MT2/*metabolism
Animals ; CHO Cells ; Cricetulus ; Drug Design ; Humans ; Isoquinolines/chemical synthesis ; Ligands ; Melatonin/chemistry ; Phosphorylation ; Protein Binding ; Receptor, Melatonin, MT1/antagonists & inhibitors ; Receptor, Melatonin, MT1/chemistry ; Receptor, Melatonin, MT2/antagonists & inhibitors ; Receptor, Melatonin, MT2/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
FVB/NJ mice demonstrate a youthful sensitivity to noise-induced hearing loss and provide a useful genetic model for the study of neural hearing loss.
Autorzy:
Ho MK; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, 90089 ; Department of Cell Biology and Genetics, House Research Institute, Los Angeles, CA 90057.
Li X; Department of Cell Biology and Genetics, House Research Institute, Los Angeles, CA 90057.
Wang J; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, 90089 ; Department of Cell Biology and Genetics, House Research Institute, Los Angeles, CA 90057.
Ohmen JD; Department of Cell Biology and Genetics, House Research Institute, Los Angeles, CA 90057.
Friedman RA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, 90089 ; Department of Cell Biology and Genetics, House Research Institute, Los Angeles, CA 90057.
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Źródło:
Audiology and neurotology. Extra [Audiol Neurotol Extra] 2014 Jan 01; Vol. 4 (1), pp. 1-11.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacokinetics, oral bioavailability and metabolism of a novel isoquinolinone-based melatonin receptor agonist in rats.
Autorzy:
Zhu J; Division of Life Sciences, and Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Hu Y
Ho MK
Wong YH
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Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2012 Nov; Vol. 42 (11), pp. 1138-50. Date of Electronic Publication: 2012 May 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Isoquinolines/*pharmacokinetics
Receptors, Melatonin/*agonists
Administration, Intravenous ; Administration, Oral ; Animals ; Biological Availability ; Blood Proteins/metabolism ; Caco-2 Cells ; Dogs ; Drug Evaluation, Preclinical ; Humans ; Isoquinolines/administration & dosage ; Isoquinolines/metabolism ; Madin Darby Canine Kidney Cells ; Male ; Microsomes, Liver/metabolism ; Rats ; Rats, Sprague-Dawley ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling.
Autorzy:
Liu AM; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Lo RKh
Guo EX
Ho MK
Ye RD
Wong YH
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Źródło:
BMC structural biology [BMC Struct Biol] 2011 Apr 13; Vol. 11, pp. 17. Date of Electronic Publication: 2011 Apr 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Vesicular Transport/*metabolism
GTP-Binding Protein alpha Subunits, Gq-G11/*chemistry
GTP-Binding Protein alpha Subunits, Gq-G11/*metabolism
Heterotrimeric GTP-Binding Proteins/*metabolism
ras Proteins/*metabolism
Enzyme Activation ; HEK293 Cells ; Humans ; Models, Molecular ; Phospholipase C beta/metabolism ; Protein Binding ; Protein Structure, Tertiary ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 26

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