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Wyświetlanie 1-8 z 8
Tytuł:
Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
Autorzy:
Ferreira MAR; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Vonk JM; University of Groningen, University Medical Center Groningen, Epidemiology, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Baurecht H; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Marenholz I; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.
Tian C; 23andMe, Inc., Mountain View, California, United States of America.
Hoffman JD; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America.
Helmer Q; Department Biological Psychology, Netherlands Twin Register, Vrije University, Amsterdam, The Netherlands.
Tillander A; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
Ullemar V; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
Lu Y; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
Grosche S; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Rüschendorf F; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.
Granell R; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.
Brumpton BM; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Thoracic Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Fritsche LG; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Nielsen JB; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Zhou W; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Langhammer A; The HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Holmen OL; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
Løset M; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Dermatology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Abecasis GR; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
Willer CJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Emami NC; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America.
Cavazos TB; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.
Witte JS; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America.; Institute for Human Genetics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, United States of America.
Szwajda A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hinds DA; 23andMe, Inc., Mountain View, California, United States of America.
Hübner N; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.
Weidinger S; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Magnusson PK; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America.
Karlsson R; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
Paternoster L; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.
Boomsma DI; Department Biological Psychology, Netherlands Twin Register, Vrije University, Amsterdam, The Netherlands.
Almqvist C; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Lee YA; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.
Koppelman GH; University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Pediatric Pulmonology and Pediatric Allergology, and University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
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Corporate Authors:
23andMe Research Team
collaborators of the SHARE study
Źródło:
PLoS genetics [PLoS Genet] 2020 Jun 30; Vol. 16 (6), pp. e1008725. Date of Electronic Publication: 2020 Jun 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Single Nucleotide*
Asthma/*genetics
Eczema/*genetics
Rhinitis, Allergic, Seasonal/*genetics
Adolescent ; Adult ; Age of Onset ; Aged ; Asthma/pathology ; Child ; Eczema/pathology ; Female ; Genetic Loci ; Genome-Wide Association Study/methods ; Humans ; Male ; Middle Aged ; Rhinitis, Allergic, Seasonal/pathology
Czasopismo naukowe
Tytuł:
Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation.
Autorzy:
Thorolfsdottir RB; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Sveinbjornsson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Sulem P; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
Jonsson S; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Halldorsson GH; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Melsted P; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Ivarsdottir EV; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Davidsson OB; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Kristjansson RP; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Thorleifsson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Helgadottir A; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Gretarsdottir S; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Norddahl G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Rajamani S; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Torfason B; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland.
Valgardsson AS; Department of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland.
Sverrisson JT; Department of Medicine, Akureyri Regional Hospital, Akureyri, Iceland.
Tragante V; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Cardiology, St. Olav's University Hospital, Trondheim, Norway.
Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK.
Roden DM; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Darbar D; Division of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Pedersen TR; Center For Preventive Medicine, Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway.
Sabatine MS; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Løchen ML; Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
Halldorsson BV; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Reykjavik University, Reykjavik, Iceland.
Jonsdottir I; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of immunology, Landspitali University Hospital, Reykjavik, Iceland.
Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.
Arnar DO; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali University Hospital, Reykjavik, Iceland.
Thorsteinsdottir U; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Gudbjartsson DF; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Holm H; deCODE genetics/Amgen, Inc., Reykjavik, Iceland. .
Stefansson K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland. .; Faculty of Medicine, University of Iceland, Reykjavik, Iceland. .
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Źródło:
Communications biology [Commun Biol] 2018 Jun 12; Vol. 1, pp. 68. Date of Electronic Publication: 2018 Jun 12 (Print Publication: 2018).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.
Autorzy:
Holmen OL; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. [3].
Zhang H; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2].
Fan Y; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2].
Hovelson DH; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
Schmidt EM; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
Zhou W; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Guo Y; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Zhang J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Langhammer A; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.
Løchen ML; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Ganesh SK; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
Vatten L; Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway.
Skorpen F; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.
Dalen H; 1] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway. [2] Medical Imaging Laboratory for Innovative Future Healthcare, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Zhang J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Pennathur S; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA.
Chen J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Platou C; Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
Mathiesen EB; 1] Brain and Circulation Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway. [2] Brain and Circulation Research Group, University Hospital of North Norway, Tromsø, Norway.
Wilsgaard T; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Njølstad I; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Chen YE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Abecasis GR; Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Hveem K; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
Willer CJ; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
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Źródło:
Nature genetics [Nat Genet] 2014 Apr; Vol. 46 (4), pp. 345-51. Date of Electronic Publication: 2014 Mar 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Variation*
Lipids/*blood
Membrane Proteins/*genetics
Myocardial Infarction/*epidemiology
Myocardial Infarction/*genetics
Animals ; Cholesterol, LDL/blood ; Cholesterol, LDL/genetics ; Exome/genetics ; Gene Knockdown Techniques ; Genome-Wide Association Study ; Genotype ; Humans ; Lipids/genetics ; Mice ; Mice, Inbred C57BL ; Mutation, Missense/genetics ; Norway/epidemiology ; Risk Factors
Czasopismo naukowe
Tytuł:
Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study.
Autorzy:
Kvehaugen AS
Melien Ø
Holmen OL
Laivuori H
Dechend R
Staff AC; From the Department of Obstetrics and Department of Gynecology, Oslo University Hospital, Ulleval, Oslo, Norway and Faculty of Medicine, University of Oslo, Oslo, Norway. .
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Źródło:
BMC medical genetics [BMC Med Genet] 2014 Mar 05; Vol. 15, pp. 28. Date of Electronic Publication: 2014 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Polymorphism, Single Nucleotide*
Hypertension/*genetics
Pre-Eclampsia/*genetics
RGS Proteins/*genetics
Adult ; Case-Control Studies ; Exercise ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Hypertension/epidemiology ; Norway ; Pre-Eclampsia/epidemiology ; Pregnancy ; Prevalence ; Risk Factors
Czasopismo naukowe
Tytuł:
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Autorzy:
Mahajan A
Go MJ
Zhang W
Below JE
Gaulton KJ
Ferreira T
Horikoshi M
Johnson AD
Ng MC
Prokopenko I
Saleheen D
Wang X
Zeggini E
Abecasis GR
Adair LS
Almgren P
Atalay M
Aung T
Baldassarre D
Balkau B
Bao Y
Barnett AH
Barroso I
Basit A
Been LF
Beilby J
Bell GI
Benediktsson R
Bergman RN
Boehm BO
Boerwinkle E
Bonnycastle LL
Burtt N
Cai Q
Campbell H
Carey J
Cauchi S
Caulfield M
Chan JC
Chang LC
Chang TJ
Chang YC
Charpentier G
Chen CH
Chen H
Chen YT
Chia KS
Chidambaram M
Chines PS
Cho NH
Cho YM
Chuang LM
Collins FS
Cornelis MC
Couper DJ
Crenshaw AT
van Dam RM
Danesh J
Das D
de Faire U
Dedoussis G
Deloukas P
Dimas AS
Dina C
Doney AS
Donnelly PJ
Dorkhan M
van Duijn C
Dupuis J
Edkins S
Elliott P
Emilsson V
Erbel R
Eriksson JG
Escobedo J
Esko T
Eury E
Florez JC
Fontanillas P
Forouhi NG
Forsen T
Fox C
Fraser RM
Frayling TM
Froguel P
Frossard P
Gao Y
Gertow K
Gieger C
Gigante B
Grallert H
Grant GB
Grrop LC
Groves CJ
Grundberg E
Guiducci C
Hamsten A
Han BG
Hara K
Hassanali N
Hattersley AT
Hayward C
Hedman AK
Herder C
Hofman A
Holmen OL
Hovingh K
Hreidarsson AB
Hu C
Hu FB
Hui J
Humphries SE
Hunt SE
Hunter DJ
Hveem K
Hydrie ZI
Ikegami H
Illig T
Ingelsson E
Islam M
Isomaa B
Jackson AU
Jafar T
James A
Jia W
Jöckel KH
Jonsson A
Jowett JB
Kadowaki T
Kang HM
Kanoni S
Kao WH
Kathiresan S
Kato N
Katulanda P
Keinanen-Kiukaanniemi KM
Kelly AM
Khan H
Khaw KT
Khor CC
Kim HL
Kim S
Kim YJ
Kinnunen L
Klopp N
Kong A
Korpi-Hyövälti E
Kowlessur S
Kraft P
Kravic J
Kristensen MM
Krithika S
Kumar A
Kumate J
Kuusisto J
Kwak SH
Laakso M
Lagou V
Lakka TA
Langenberg C
Langford C
Lawrence R
Leander K
Lee JM
Lee NR
Li M
Li X
Li Y
Liang J
Liju S
Lim WY
Lind L
Lindgren CM
Lindholm E
Liu CT
Liu JJ
Lobbens S
Long J
Loos RJ
Lu W
Luan J
Lyssenko V
Ma RC
Maeda S
Mägi R
Männisto S
Matthews DR
Meigs JB
Melander O
Metspalu A
Meyer J
Mirza G
Mihailov E
Moebus S
Mohan V
Mohlke KL
Morris AD
Mühleisen TW
Müller-Nurasyid M
Musk B
Nakamura J
Nakashima E
Navarro P
Ng PK
Nica AC
Nilsson PM
Njølstad I
Nöthen MM
Ohnaka K
Ong TH
Owen KR
Palmer CN
Pankow JS
Park KS
Parkin M
Pechlivanis S
Pedersen NL
Peltonen L
Perry JR
Peters A
Pinidiyapathirage JM
Platou CG
Potter S
Price JF
Qi L
Radha V
Rallidis L
Rasheed A
Rathman W
Rauramaa R
Raychaudhuri S
Rayner NW
Rees SD
Rehnberg E
Ripatti S
Robertson N
Roden M
Rossin EJ
Rudan I
Rybin D
Saaristo TE
Salomaa V
Saltevo J
Samuel M
Sanghera DK
Saramies J
Scott J
Scott LJ
Scott RA
Segrè AV
Sehmi J
Sennblad B
Shah N
Shah S
Shera AS
Shu XO
Shuldiner AR
Sigurđsson G
Sijbrands E
Silveira A
Sim X
Sivapalaratnam S
Small KS
So WY
Stančáková A
Stefansson K
Steinbach G
Steinthorsdottir V
Stirrups K
Strawbridge RJ
Stringham HM
Sun Q
Suo C
Syvänen AC
Takayanagi R
Takeuchi F
Tay WT
Teslovich TM
Thorand B
Thorleifsson G
Thorsteinsdottir U
Tikkanen E
Trakalo J
Tremoli E
Trip MD
Tsai FJ
Tuomi T
Tuomilehto J
Uitterlinden AG
Valladares-Salgado A
Vedantam S
Veglia F
Voight BF
Wang C
Wareham NJ
Wennauer R
Wickremasinghe AR
Wilsgaard T
Wilson JF
Wiltshire S
Winckler W
Wong TY
Wood AR
Wu JY
Wu Y
Yamamoto K
Yamauchi T
Yang M
Yengo L
Yokota M
Young R
Zabaneh D
Zhang F
Zhang R
Zheng W
Zimmet PZ
Altshuler D
Bowden DW
Cho YS
Cox NJ
Cruz M
Hanis CL
Kooner J
Lee JY
Seielstad M
Teo YY
Boehnke M
Parra EJ
Chambers JC
Tai ES
McCarthy MI
Morris AP
Pokaż więcej
Corporate Authors:
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium
South Asian Type 2 Diabetes (SAT2D) Consortium
Mexican American Type 2 Diabetes (MAT2D) Consortium
Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium
Źródło:
Nature genetics [Nat Genet] 2014 Mar; Vol. 46 (3), pp. 234-44. Date of Electronic Publication: 2014 Feb 09.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2/*genetics
Alleles ; Asian People/genetics ; Case-Control Studies ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Hispanic or Latino/genetics ; Humans ; Polymorphism, Single Nucleotide ; Risk Factors ; White People/genetics
Czasopismo naukowe
Tytuł:
Meta-analysis of gene-level tests for rare variant association.
Autorzy:
Liu DJ; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2].
Peloso GM; 1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [4].
Zhan X; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2].
Holmen OL; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway. [3].
Zawistowski M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Feng S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Nikpay M; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Auer PL; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Goel A; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK.
Zhang H; 1] Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Peters U; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.
Farrall M; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK.
Orho-Melander M; 1] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK. [2] Department of Clinical Sciences, Lund University, Malmö, Sweden.
Kooperberg C; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] Department of Biostatistics, University of Washington School of Public Health, Seattle, Washington, USA.
McPherson R; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Watkins H; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK.
Willer CJ; 1] Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Hveem K; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
Melander O; 1] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK. [2] Department of Clinical Sciences, Lund University, Malmö, Sweden.
Kathiresan S; 1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [5].
Abecasis GR; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2].
Pokaż więcej
Źródło:
Nature genetics [Nat Genet] 2014 Feb; Vol. 46 (2), pp. 200-4. Date of Electronic Publication: 2013 Dec 15.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Variation*
Meta-Analysis as Topic*
Research Design*
Genetic Association Studies/*methods
Lipids/*genetics
Data Interpretation, Statistical ; Exome/genetics ; Genetics, Population ; Genotype ; Humans ; Lipids/blood ; Models, Genetic ; Monte Carlo Method
Czasopismo naukowe
Tytuł:
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Autorzy:
Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, UK. />Voight BF
Teslovich TM
Ferreira T
Segrè AV
Steinthorsdottir V
Strawbridge RJ
Khan H
Grallert H
Mahajan A
Prokopenko I
Kang HM
Dina C
Esko T
Fraser RM
Kanoni S
Kumar A
Lagou V
Langenberg C
Luan J
Lindgren CM
Müller-Nurasyid M
Pechlivanis S
Rayner NW
Scott LJ
Wiltshire S
Yengo L
Kinnunen L
Rossin EJ
Raychaudhuri S
Johnson AD
Dimas AS
Loos RJ
Vedantam S
Chen H
Florez JC
Fox C
Liu CT
Rybin D
Couper DJ
Kao WH
Li M
Cornelis MC
Kraft P
Sun Q
van Dam RM
Stringham HM
Chines PS
Fischer K
Fontanillas P
Holmen OL
Hunt SE
Jackson AU
Kong A
Lawrence R
Meyer J
Perry JR
Platou CG
Potter S
Rehnberg E
Robertson N
Sivapalaratnam S
Stančáková A
Stirrups K
Thorleifsson G
Tikkanen E
Wood AR
Almgren P
Atalay M
Benediktsson R
Bonnycastle LL
Burtt N
Carey J
Charpentier G
Crenshaw AT
Doney AS
Dorkhan M
Edkins S
Emilsson V
Eury E
Forsen T
Gertow K
Gigante B
Grant GB
Groves CJ
Guiducci C
Herder C
Hreidarsson AB
Hui J
James A
Jonsson A
Rathmann W
Klopp N
Kravic J
Krjutškov K
Langford C
Leander K
Lindholm E
Lobbens S
Männistö S
Mirza G
Mühleisen TW
Musk B
Parkin M
Rallidis L
Saramies J
Sennblad B
Shah S
Sigurðsson G
Silveira A
Steinbach G
Thorand B
Trakalo J
Veglia F
Wennauer R
Winckler W
Zabaneh D
Campbell H
van Duijn C
Uitterlinden AG
Hofman A
Sijbrands E
Abecasis GR
Owen KR
Zeggini E
Trip MD
Forouhi NG
Syvänen AC
Eriksson JG
Peltonen L
Nöthen MM
Balkau B
Palmer CN
Lyssenko V
Tuomi T
Isomaa B
Hunter DJ
Qi L
Shuldiner AR
Roden M
Barroso I
Wilsgaard T
Beilby J
Hovingh K
Price JF
Wilson JF
Rauramaa R
Lakka TA
Lind L
Dedoussis G
Njølstad I
Pedersen NL
Khaw KT
Wareham NJ
Keinanen-Kiukaanniemi SM
Saaristo TE
Korpi-Hyövälti E
Saltevo J
Laakso M
Kuusisto J
Metspalu A
Collins FS
Mohlke KL
Bergman RN
Tuomilehto J
Boehm BO
Gieger C
Hveem K
Cauchi S
Froguel P
Baldassarre D
Tremoli E
Humphries SE
Saleheen D
Danesh J
Ingelsson E
Ripatti S
Salomaa V
Erbel R
Jöckel KH
Moebus S
Peters A
Illig T
de Faire U
Hamsten A
Morris AD
Donnelly PJ
Frayling TM
Hattersley AT
Boerwinkle E
Melander O
Kathiresan S
Nilsson PM
Deloukas P
Thorsteinsdottir U
Groop LC
Stefansson K
Hu F
Pankow JS
Dupuis J
Meigs JB
Altshuler D
Boehnke M
McCarthy MI
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Corporate Authors:
Wellcome Trust Case Control Consortium
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators
Genetic Investigation of ANthropometric Traits (GIANT) Consortium
Asian Genetic Epidemiology Network–Type 2 Diabetes (AGEN-T2D) Consortium
South Asian Type 2 Diabetes (SAT2D) Consortium
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Źródło:
Nature genetics [Nat Genet] 2012 Sep; Vol. 44 (9), pp. 981-90. Date of Electronic Publication: 2012 Aug 12.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Predisposition to Disease*/genetics
Diabetes Mellitus, Type 2/*genetics
Genome-Wide Association Study/*statistics & numerical data
Case-Control Studies ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Genes/physiology ; Humans ; Linkage Disequilibrium ; Male ; Pakistan/epidemiology ; Polymorphism, Single Nucleotide/physiology ; Sex Factors
Czasopismo naukowe
Tytuł:
Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.
Autorzy:
Chan Y; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Holmen OL
Dauber A
Vatten L
Havulinna AS
Skorpen F
Kvaløy K
Silander K
Nguyen TT
Willer C
Boehnke M
Perola M
Palotie A
Salomaa V
Hveem K
Frayling TM
Hirschhorn JN
Weedon MN
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Źródło:
PLoS genetics [PLoS Genet] 2011 Dec; Vol. 7 (12), pp. e1002439. Date of Electronic Publication: 2011 Dec 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Alleles*
Body Height/*genetics
Multifactorial Inheritance/*genetics
Adolescent ; Adult ; Aged ; Cohort Studies ; Female ; Gene Frequency/genetics ; Genetic Association Studies ; Humans ; Male ; Middle Aged ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait, Heritable ; Siblings
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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