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    Wyświetlanie 1-3 z 3
    Tytuł:
    Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
    Autorzy:
    Hurlburt NK; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Homad LJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Sinha I; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Jennewein MF; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    MacCamy AJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Wan YH; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Boonyaratanakornkit J; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Sholukh AM; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Jackson AM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
    Zhou P; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.
    Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
    Andrabi R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.
    Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
    Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
    Stamatatos L; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA. .
    Pancera M; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Vaccine Research Center, NAID, NIH, Bethesda, MD, USA. .
    McGuire AT; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA. .; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA. .
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    Źródło:
    Communications biology [Commun Biol] 2022 Apr 11; Vol. 5 (1), pp. 342. Date of Electronic Publication: 2022 Apr 11.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
    MeSH Terms:
    COVID-19*
    SARS-CoV-2*
    Animals ; Antibodies, Monoclonal ; Antibodies, Neutralizing ; Antibodies, Viral ; Epitopes ; Spike Glycoprotein, Coronavirus/chemistry
    SCR Organism:
    SARS-CoV-2 variants
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Designed proteins assemble antibodies into modular nanocages.
    Autorzy:
    Divine R; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Dang HV; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
    Ueda G; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Fallas JA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Vulovic I; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Sheffler W; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Saini S; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.
    Zhao YT; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.; Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA.
    Raj IX; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.
    Morawski PA; Benaroya Research Institute, Seattle, WA 98101, USA.
    Jennewein MF; Vaccines and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98019, USA.
    Homad LJ; Vaccines and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98019, USA.
    Wan YH; Vaccines and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98019, USA.
    Tooley MR; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Seeger F; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Etemadi A; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Medical Biotechnology Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
    Fahning ML; Benaroya Research Institute, Seattle, WA 98101, USA.
    Lazarovits J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Roederer A; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
    Stewart L; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Mazloomi M; Medical Biotechnology Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
    King NP; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
    Campbell DJ; Benaroya Research Institute, Seattle, WA 98101, USA.
    McGuire AT; Vaccines and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98019, USA.; Department of Global Health, University of Washington, Seattle, WA 98195, USA.
    Stamatatos L; Vaccines and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98019, USA.; Department of Global Health, University of Washington, Seattle, WA 98195, USA.
    Ruohola-Baker H; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.
    Mathieu J; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.
    Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
    Baker D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. .; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2021 Apr 02; Vol. 372 (6537).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Nanostructures*
    Protein Engineering*
    Signal Transduction*
    Antibodies/*chemistry
    Antibodies/*immunology
    Angiopoietins/chemistry ; Angiopoietins/immunology ; Angiopoietins/metabolism ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; B-Lymphocytes/immunology ; CD40 Antigens/chemistry ; CD40 Antigens/immunology ; CD40 Antigens/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Computer Simulation ; Genes, Synthetic ; Humans ; Immunoglobulin Fc Fragments/chemistry ; Lymphocyte Activation ; Models, Molecular ; Protein Binding ; Receptor, TIE-2/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/immunology ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; SARS-CoV-2/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection.
    Autorzy:
    Stamatatos L; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA.
    Czartoski J; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Wan YH; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Homad LJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Rubin V; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Glantz H; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Neradilek M; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Seydoux E; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Jennewein MF; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    MacCamy AJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Feng J; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Mize G; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    De Rosa SC; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
    Finzi A; Centre de Recherche du CHUM, Montréal, QC, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada.
    Lemos MP; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Cohen KW; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    Moodie Z; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA.
    McElrath MJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.
    McGuire AT; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2021 Mar 25. Date of Electronic Publication: 2021 Mar 25.
    Typ publikacji:
    Editorial
    Opinia redakcyjna
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-3 z 3

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