Temat: "Homeodomain Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids.
Autorzy:: Pan D; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. dengpan_.
Zhang X; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Jin K; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Jin ZB; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2023 Dec 05; Vol. 14 (1), pp. 346. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:: Journal Article
MeSH Terms:: Haploinsufficiency*
Homeodomain Proteins*/genetics
Trans-Activators*/genetics
Animals ; Humans ; Mice ; Cell Differentiation/genetics ; Organoids ; Photoreceptor Cells ; Retina/metabolism

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Skocz do pozycji: 2.

Tytuł:: Transcription factor interactions explain the context-dependent activity of CRX binding sites.
Autorzy:: Loell KJ; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.; The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
Friedman RZ; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.; The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
Myers CA; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
Corbo JC; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
Cohen BA; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.; The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
White MA; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.; The Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2024 Jan 16; Vol. 20 (1), pp. e1011802. Date of Electronic Publication: 2024 Jan 16 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Transcription Factors*/metabolism
Trans-Activators*/metabolism
Homeodomain Proteins/genetics ; Gene Expression Regulation ; Binding Sites/genetics ; Retina

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Skocz do pozycji: 3.

Tytuł:: IGF2BP3‑stabilized SIX4 promotes the proliferation, migration, invasion and tube formation of ovarian cancer cells.
Autorzy:: Han J; Department of Gynecology Nursing, West China Second University Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Hu X; Department of Gynecology Nursing, West China Second University Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, Sichuan 610041, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2022 Jul; Vol. 26 (1). Date of Electronic Publication: 2022 May 26.
Typ publikacji:: Journal Article
MeSH Terms:: Homeodomain Proteins*/genetics
Homeodomain Proteins*/metabolism
Ovarian Neoplasms*/pathology
RNA-Binding Proteins*/genetics
Trans-Activators*/genetics
Trans-Activators*/metabolism
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Female ; Gene Expression Regulation, Neoplastic ; Genes, Homeobox ; Humans ; Neovascularization, Pathologic/genetics ; RNA ; RNA, Messenger

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Skocz do pozycji: 4.

Tytuł:: Hmx1 regulates urfh1 expression in the craniofacial region in zebrafish.
Autorzy:: El Fersioui Y; IRO - Institute for Research in Ophthalmology, Sion, Switzerland.
Pinton G; IRO - Institute for Research in Ophthalmology, Sion, Switzerland.
Allaman-Pillet N; IRO - Institute for Research in Ophthalmology, Sion, Switzerland.
Schorderet DF; IRO - Institute for Research in Ophthalmology, Sion, Switzerland.; Faculty of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jan 19; Vol. 16 (1), pp. e0245239. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Eye/*metabolism
Homeodomain Proteins/*metabolism
Trans-Activators/*metabolism
Zebrafish/*metabolism
Zebrafish Proteins/*metabolism
Amino Acid Sequence ; Animals ; Animals, Genetically Modified/metabolism ; Dimerization ; Embryo, Nonmammalian/metabolism ; Eye/growth & development ; Gene Expression Regulation, Developmental ; Homeodomain Proteins/chemistry ; Homeodomain Proteins/genetics ; Mutagenesis ; Promoter Regions, Genetic ; Trans-Activators/genetics ; Zebrafish/growth & development ; Zebrafish Proteins/chemistry ; Zebrafish Proteins/genetics

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Skocz do pozycji: 5.

Tytuł:: Interaction of human CRX and NRL in live HEK293T cells measured using fluorescence resonance energy transfer (FRET).
Autorzy:: Zhuo X; Departments of Ophthalmology & Visual Sciences and Biochemistry & Molecular Biology, Center for Vision Research, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.; CLIA Laboratory, The Jackson Laboratory for Genomic Medicine, University of Connecticut Health Center, 10 Discovery Dr., Farmington, CT, 06032, USA.
Knox BE; Departments of Ophthalmology & Visual Sciences and Biochemistry & Molecular Biology, Center for Vision Research, SUNY Upstate Medical University, Syracuse, NY, 13210, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Apr 28; Vol. 12 (1), pp. 6937. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji:: Journal Article
MeSH Terms:: Fluorescence Resonance Energy Transfer*/methods
Transcription Factors*/metabolism
Basic-Leucine Zipper Transcription Factors/*analysis
Eye Proteins/*analysis
Homeodomain Proteins/*analysis
Trans-Activators/*analysis
DNA/metabolism ; HEK293 Cells ; Humans ; Retina/metabolism

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Skocz do pozycji: 6.

Tytuł:: Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF.
Autorzy:: Lee SI; Department of Animal Biotechnology, Kyungpook National University, Gyeongsangbuk-do, Sangju 37224, Korea.
Kim IH; Department of Animal Resource and Science, Dankook University, Chungcheongnam-do, Cheonan-si 330-714, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 03; Vol. 21 (13). Date of Electronic Publication: 2020 Jul 03.
Typ publikacji:: Journal Article
MeSH Terms:: Dioxins/*therapeutic use
Heparin-binding EGF-like Growth Factor/*metabolism
Homeodomain Proteins/*metabolism
Intestinal Diseases/*drug therapy
Intestinal Diseases/*metabolism
Intestines/*drug effects
Trans-Activators/*metabolism
Animals ; Animals, Suckling ; Cell Line ; Gene Expression Regulation, Developmental/drug effects ; Heparin-binding EGF-like Growth Factor/genetics ; Homeodomain Proteins/genetics ; Intestinal Diseases/genetics ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Intestines/growth & development ; MAP Kinase Signaling System/drug effects ; Oxidative Stress/drug effects ; Signal Transduction/drug effects ; Sus scrofa ; Trans-Activators/genetics ; Weaning ; Wound Healing/drug effects

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Skocz do pozycji: 7.

Tytuł:: Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice.
Autorzy:: Walcheck MT; McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, United States of America.
Matkowskyj KA; University of Wisconsin Carbone Cancer Center, Madison, WI, United States of America.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.; William S. Middleton Memorial Veterans Hospital, Madison, WI, United States of America.
Turco A; Division of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Blaine-Sauer S; McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, United States of America.
Nukaya M; Division of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Noel J; McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, United States of America.
Ronnekleiv OK; Department of Chemical Physiology and Biochemistry, Oregon Health & Sciences University, Portland, OR, United States of America.
Ronnekleiv-Kelly SM; McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, United States of America.; University of Wisconsin Carbone Cancer Center, Madison, WI, United States of America.; Division of Surgical Oncology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Nov 04; Vol. 16 (11), pp. e0259245. Date of Electronic Publication: 2021 Nov 04 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anus Neoplasms/*pathology
Carcinoma, Squamous Cell/*pathology
Homeodomain Proteins/*genetics
Proto-Oncogene Proteins p21(ras)/*genetics
Trans-Activators/*genetics
Animals ; Anus Neoplasms/genetics ; Anus Neoplasms/metabolism ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Estrogens/metabolism ; Female ; Male ; Mice ; Mutation ; Ovariectomy ; Sex Factors

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Skocz do pozycji: 8.

Tytuł:: The CDK inhibitor p57 enhances the activity of the transcriptional coactivator FHL2.
Autorzy:: Kullmann MK; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria. .
Podmirseg SR; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.
Roilo M; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.
Hengst L; Institute of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Apr 28; Vol. 10 (1), pp. 7140. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cyclin-Dependent Kinase Inhibitor p57/*physiology
LIM-Homeodomain Proteins/*physiology
Muscle Proteins/*physiology
Trans-Activators/*physiology
Transcription Factors/*physiology
Chromatin Assembly and Disassembly ; Cyclin-Dependent Kinase Inhibitor p57/metabolism ; Gene Expression Regulation ; HEK293 Cells ; Humans ; LIM-Homeodomain Proteins/metabolism ; Muscle Proteins/metabolism ; Protein Binding ; Subcellular Fractions/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic

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Skocz do pozycji: 9.

Tytuł:: bicoid RNA localization requires the trans -Golgi network.
Autorzy:: Cai X; 1Department of Experimental Medical Sciences, Lund University, BMC D10, S-22184 Lund, Sweden.
Fahmy K; 2Present Address: Department of Genetics, Ain Shams University, Cairo, Egypt.
Baumgartner S; 1Department of Experimental Medical Sciences, Lund University, BMC D10, S-22184 Lund, Sweden.; 3Department of Biology, University of Konstanz, D-78457 Constance, Germany.; Pokaż więcej
Źródło:: Hereditas [Hereditas] 2019 Sep 10; Vol. 156, pp. 30. Date of Electronic Publication: 2019 Sep 10 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: RNA Transport*
trans-Golgi Network*
Drosophila Proteins/*genetics
Homeodomain Proteins/*genetics
Trans-Activators/*genetics
Animals ; Chromosomes, Insect ; Drosophila/genetics ; Drosophila/metabolism ; Drosophila Proteins/metabolism ; Homeodomain Proteins/metabolism ; Protein Transport ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Trans-Activators/metabolism

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Skocz do pozycji: 10.

Tytuł:: Iranian neonatal diabetes mellitus due to mutation in PDX1 gene: a case report.
Autorzy:: Sahebi L; Institute of Family Health , Breastfeeding Research Center, Tehran University of Medical Science, Tehran, Iran.
Niknafs N; Institute of Family Health , Breastfeeding Research Center, Tehran University of Medical Science, Tehran, Iran.
Dalili H; Institute of Family Health , Breastfeeding Research Center, Tehran University of Medical Science, Tehran, Iran.
Amini E; Institute of Family Health, Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran.
Esmaeilnia T; Institute of Family Health, Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran.
Amoli M; Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farrokhzad N; Institute of Family Health, Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran. .; Pokaż więcej
Źródło:: Journal of medical case reports [J Med Case Rep] 2019 Aug 01; Vol. 13 (1), pp. 258. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Homeodomain Proteins*
Trans-Activators*
Diabetes Mellitus/*genetics
Hyperglycemia/*genetics
Diabetes Mellitus/blood ; Diabetes Mellitus/drug therapy ; Humans ; Hyperglycemia/blood ; Hyperglycemia/drug therapy ; Infant ; Infant, Newborn ; Infant, Newborn, Diseases ; Insulin/administration & dosage ; Iran ; Male ; Mutation

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Skocz do pozycji: 11.

Tytuł:: Homeobox genes in melatonin-producing pinealocytes: Otx2 and Crx act to promote hormone synthesis in the mature rat pineal gland.
Autorzy:: Rohde K; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hertz H; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Rath MF; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Pokaż więcej
Źródło:: Journal of pineal research [J Pineal Res] 2019 May; Vol. 66 (4), pp. e12567. Date of Electronic Publication: 2019 Mar 20.
Typ publikacji:: Journal Article
MeSH Terms:: Homeodomain Proteins/*metabolism
Melatonin/*metabolism
Otx Transcription Factors/*metabolism
Pineal Gland/*metabolism
Trans-Activators/*metabolism
Animals ; Gene Expression Regulation, Developmental/genetics ; Gene Expression Regulation, Developmental/physiology ; Homeodomain Proteins/genetics ; Immunohistochemistry ; Male ; Otx Transcription Factors/genetics ; Rats ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction ; Trans-Activators/genetics

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Skocz do pozycji: 12.

Tytuł:: PDX1 and MC4R genetic polymorphisms are associated with type 2 diabetes mellitus risk in the Chinese Han population.
Autorzy:: Wang N; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Tong R; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Xu J; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Tian Y; Department of Oncology, East Branch of the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710089, Shaanxi, China.
Pan J; Department of Endocrinology, Xianyang Central Hospital, Xianyang, 712000, Shaanxi, China.
Cui J; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Chen H; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Peng Y; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Fei S; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Yang S; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Wang L; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Yao J; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Cui W; Department of Endocrinology and Second Department of Geriatrics, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, 710061, Shaanxi, China. .; Pokaż więcej
Źródło:: BMC medical genomics [BMC Med Genomics] 2021 Oct 25; Vol. 14 (1), pp. 249. Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Diabetes Mellitus, Type 2/*genetics
Ethnicity/*genetics
Homeodomain Proteins/*genetics
Receptor, Melanocortin, Type 4/*genetics
Trans-Activators/*genetics
Aged ; Case-Control Studies ; China ; Female ; Humans ; Male ; Middle Aged

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Skocz do pozycji: 13.

Tytuł:: Modulating the bicoid gradient in space and time.
Autorzy:: Cai X; Departmentof Experimental Medical Sciences, Lund University, BMC D10, 22184, Lund, Sweden.
Rondeel I; Departmentof Experimental Medical Sciences, Lund University, BMC D10, 22184, Lund, Sweden.; Present address: Hubrecht Institute, 3584 CT, Utrecht, The Netherlands.
Baumgartner S; Departmentof Experimental Medical Sciences, Lund University, BMC D10, 22184, Lund, Sweden. .; Department of Biology, University of Konstanz, 78457, Konstanz, Germany. .; Pokaż więcej
Źródło:: Hereditas [Hereditas] 2021 Aug 17; Vol. 158 (1), pp. 29. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Drosophila/*genetics
Drosophila Proteins/*genetics
Homeodomain Proteins/*genetics
Trans-Activators/*genetics
Animals ; Cyclin B/genetics ; Drosophila/embryology ; Gene Expression Regulation, Developmental ; Poly A/genetics ; Polynucleotide Adenylyltransferase/genetics ; RNA, Messenger/genetics

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Skocz do pozycji: 14.

Tytuł:: Development of thymic tumor in [LSL:Kras ; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis.
Autorzy:: Liot S; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France.
El Kholti N; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France.
Balas J; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France.
Genestier L; UR LIB « Lymphoma Immuno-Biology', Université Claude Bernard Lyon I, Lyon, France.
Verrier B; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France.
Valcourt U; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France.
Lambert E; Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI), UMR CNRS 5305, Université Claude Bernard Lyon 1, Institut de Biologie et Chimie Des Protéines, 7, passage du Vercors, 69367, Lyon Cedex 07, France. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jul 23; Vol. 11 (1), pp. 15075. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinogenesis/*genetics
Homeodomain Proteins/*genetics
Pancreatic Neoplasms/*genetics
Pancreatic Neoplasms/*pathology
Proto-Oncogene Proteins p21(ras)/*genetics
Thymus Neoplasms/*genetics
Trans-Activators/*genetics
Animals ; Carcinogenesis/pathology ; Carcinoma in Situ/genetics ; Carcinoma in Situ/pathology ; Carcinoma, Pancreatic Ductal/genetics ; Carcinoma, Pancreatic Ductal/pathology ; Disease Models, Animal ; Female ; Male ; Mice ; Pancreas/pathology ; Pancreatic Ducts/pathology ; Thymoma/genetics ; Thymoma/pathology ; Thymus Neoplasms/pathology ; Pancreatic Neoplasms
SCR Disease Name:: Thymoma, Familial

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Skocz do pozycji: 15.

Tytuł:: PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways.
Autorzy:: Uzozie AC; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Ergin EK; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Rolf N; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Tsui J; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Lorentzian A; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Weng SSH; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.
Nierves L; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Smith TG; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Lim CJ; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Maxwell CA; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Reid GSD; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Lange PF; Department of Pathology, University of British Columbia, Vancouver, BC, Canada. .; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada. .; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2021 Mar 15; Vol. 40 (1), pp. 96. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Homeodomain Proteins/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Proteome/*metabolism
Trans-Activators/*metabolism
Animals ; Disease Models, Animal ; Humans ; Mice ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 16.

Tytuł:: Upregulation of SIX4 indicates poor clinical outcome and promotes tumor growth and cell metastasis in esophageal squamous cell carcinoma.
Autorzy:: Li Y; Department of Gastroenterology, Rizhao Hospital of TCM, Rizhao, China.
Jiang X; Outpatient Department, Qingdao Eighth People's Hospital, Qingdao, China.
Yan X; Health Management Department, Qingdao Eighth People's Hospital, Qingdao, China.
Wang Y; Department of Clinical Laboratory, Yantaishan Hospital, Yantai, China.; Pokaż więcej
Źródło:: Thoracic cancer [Thorac Cancer] 2021 Mar; Vol. 12 (6), pp. 752-759. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji:: Journal Article
MeSH Terms:: Esophageal Neoplasms/*metabolism
Esophageal Squamous Cell Carcinoma/*genetics
Homeodomain Proteins/*metabolism
Trans-Activators/*metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation/physiology ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma/pathology ; Heterografts ; Humans ; Male ; Mice ; Mice, SCID ; Middle Aged ; Neoplasm Metastasis ; Prognosis ; Transfection ; Treatment Outcome ; Up-Regulation

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Skocz do pozycji: 17.

Tytuł:: SIX6 -related anophthalmia/microphthalmia: second report on a deletion in a consanguineous family.
Autorzy:: Deepthi A; Centre for Arab Genomic Studies , Dubai, United Arab Emirates.
Fakhoury O; Saint George Hospital , Beirut, Lebanon.
Daher M; Faculty of Medicine, Saint Joseph University , Beirut, Lebanon.
Gambarini A; Institut Jérôme Lejeune , Paris, France.
El-Hayek S; Centre for Arab Genomic Studies , Dubai, United Arab Emirates.
Megarbane A; Institut Jérôme Lejeune , Paris, France.; School of Medicine, Lebanese University , Beirut, Lebanon.; Department of Human Genetics, Gilbert and Rose-Marie Ghagoury School of Medicine, Lebanese American University , Byblos, Lebanon.; Pokaż więcej
Źródło:: Ophthalmic genetics [Ophthalmic Genet] 2021 Feb; Vol. 42 (1), pp. 88-91. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Consanguinity*
Anophthalmos/*pathology
Homeodomain Proteins/*genetics
Microphthalmos/*pathology
Trans-Activators/*genetics
Anophthalmos/genetics ; Child ; Gene Deletion ; Humans ; Male ; Microphthalmos/genetics ; Prognosis

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Skocz do pozycji: 18.

Tytuł:: miR-1249-5p regulates the osteogenic differentiation of ADSCs by targeting PDX1.
Autorzy:: Yang XM; The Department of Emergency, Cangzhou Central Hospital, Cangzhou, 061000, China.
Song YQ; The Department of Emergency, Cangzhou Central Hospital, Cangzhou, 061000, China.
Li L; The Department of Emergency, Cangzhou Central Hospital, Cangzhou, 061000, China.
Liu DM; The Department of Emergency, Cangzhou Central Hospital, Cangzhou, 061000, China.
Chen GD; The Department of Orthopedics, Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou, 061000, Hebei Province, China. .; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 06; Vol. 16 (1), pp. 10. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:: Journal Article
MeSH Terms:: Adipocytes/*physiology
Adipose Tissue/*cytology
Cell Differentiation/*genetics
Gene Expression/*genetics
Gene Expression Regulation, Developmental/*genetics
Homeodomain Proteins/*genetics
Homeodomain Proteins/*metabolism
MicroRNAs/*physiology
Osteogenesis/*genetics
Stem Cells/*physiology
Trans-Activators/*genetics
Trans-Activators/*metabolism
3' Untranslated Regions ; Cells, Cultured ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/genetics ; Signal Transduction/physiology

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Tytuł:: Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice.
Autorzy:: Glavas MM; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Hui Q; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Tudurí E; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.; Centro de Investigación Biomédica en Red de Diabetes y , Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.
Erener S; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Kasteel NL; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Johnson JD; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Kieffer TJ; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada. .; Department of Surgery, University of British Columbia, Vancouver, BC, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Mar 06; Vol. 9 (1), pp. 3619. Date of Electronic Publication: 2019 Mar 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin Resistance*
Diabetes Mellitus, Experimental/*pathology
Diet, High-Fat/*adverse effects
Homeodomain Proteins/*metabolism
Insulin-Secreting Cells/*pathology
Overnutrition/*complications
Trans-Activators/*metabolism
Animals ; Blood Glucose/metabolism ; Body Weight ; Diabetes Mellitus, Experimental/etiology ; Diabetes Mellitus, Experimental/metabolism ; Female ; Homeodomain Proteins/genetics ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Male ; Mice ; Trans-Activators/genetics ; Weight Gain

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Skocz do pozycji: 20.

Tytuł:: Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm.
Autorzy:: Magli A; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Baik J; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Mills LJ; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America.
Kwak IY; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Dillon BS; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Mondragon Gonzalez R; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Stafford DA; Department of Molecular and Cell Biology, University of California, Berkeley, California, United States of America.
Swanson SA; Morgridge Institute for Research, Madison, Wisconsin, United States of America.
Stewart R; Morgridge Institute for Research, Madison, Wisconsin, United States of America.
Thomson JA; Morgridge Institute for Research, Madison, Wisconsin, United States of America.
Garry DJ; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.
Dynlacht BD; Department of Pathology, New York University Cancer Institute, New York University School of Medicine, New York, New York, United States of America.
Perlingeiro RCR; Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2019 Feb 26; Vol. 17 (2), pp. e3000153. Date of Electronic Publication: 2019 Feb 26 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromatin Assembly and Disassembly*
DNA-Binding Proteins/*genetics
Homeodomain Proteins/*genetics
Mesoderm/*metabolism
Muscle Cells/*metabolism
Muscle Development/*genetics
PAX3 Transcription Factor/*genetics
Trans-Activators/*genetics
Transcription Factors/*genetics
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Differentiation ; Cell Line ; DNA-Binding Proteins/metabolism ; Embryo, Mammalian ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Gene Expression Regulation, Developmental ; Homeodomain Proteins/metabolism ; Humans ; Mesoderm/cytology ; Mesoderm/growth & development ; Mice ; Mice, Transgenic ; Muscle Cells/cytology ; Muscle, Skeletal/cytology ; Muscle, Skeletal/growth & development ; Muscle, Skeletal/metabolism ; Myogenic Regulatory Factor 5/genetics ; Myogenic Regulatory Factor 5/metabolism ; PAX3 Transcription Factor/metabolism ; Signal Transduction ; T-Box Domain Proteins ; TEA Domain Transcription Factors ; Trans-Activators/metabolism ; Transcription Factors/metabolism

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