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Wyświetlanie 1-38 z 38
Tytuł :
Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation.
Autorzy :
Liu, Li-ping
Yan, Tian-hua
Jiang, Li-ying
Hu, Wei
Hu, Meng
Wang, Chao
Zhang, Qian
Long, Yan
Wang, Jiang-qing
Li, Yong-qi
Hu, Mei
Hong, Hao
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Temat :
DIAGNOSIS of diabetes
STREPTOZOTOCIN
PIOGLITAZONE
AMYLOID beta-protein precursor
LABORATORY mice
HIPPOCAMPUS (Brain)
BLOOD sugar
Źródło :
Acta Pharmacologica Sinica; Apr2013, Vol. 34 Issue 4, p455-463, 9p, 1 Chart, 5 Graphs
Czasopismo naukowe
Tytuł :
PPAR-γ2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China.
Autorzy :
Pei, Qi
Huang, Qiong
Yang, Guo-ping
Zhao, Ying-chun
Yin, Ji-ye
Song, Min
Zheng, Yi
Mo, Zhao-hui
Zhou, Hong-hao
Liu, Zhao-qian
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Temat :
PEROXISOME proliferator-activated receptors
GENETIC polymorphisms
TYPE 2 diabetes
PIOGLITAZONE
PROTEIN-tyrosine phosphatase
DRUG efficacy
Źródło :
Acta Pharmacologica Sinica; Feb2013, Vol. 34 Issue 2, p255-261, 7p
Terminy geograficzne :
CHINA
Czasopismo naukowe
Tytuł :
IGF2BP2 variations influence repaglinide response and risk of type 2 diabetes in Chinese population.
Autorzy :
Qiong HUANG
Ji-ye YIN
Xing-ping DAI
Qi PEI
Min DONG
Zhi-guang ZHOU
Xi HUANG
Min YU
Hong-hao ZHOU
Zhao-qian LIU
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Temat :
CARRIER proteins
TYPE 2 diabetes risk factors
GENETIC polymorphisms
HYPOGLYCEMIC agents
Źródło :
Acta Pharmacologica Sinica; Jun2010, Vol. 31 Issue 6, p709-717, 9p, 5 Charts, 3 Graphs
Terminy geograficzne :
CHINA
Czasopismo naukowe
Tytuł :
Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patients.
Autorzy :
Guo-ping YANG
Hong YUAN
Bin TANG
Wei ZHANG
Lian-sheng WANG
Zhi-jun HUANG
Dong-sheng OU-YANG
Gui-xiang ZHANG
Hong-hao ZHOU
Pokaż więcej
Temat :
GENETIC polymorphisms
HYPERLIPIDEMIA
ANTILIPEMIC agents
CHINESE people
CHOLESTEROL
TRIGLYCERIDES
HIGH density lipoproteins
Źródło :
Acta Pharmacologica Sinica; Mar2010, Vol. 31 Issue 3, p382-386, 5p, 3 Charts
Czasopismo naukowe
Tytuł :
Distributive characteristics of Ser49Gly and Gly389Arg genetic polymorphisms of β1-adrenoceptor in Chinese Han and Dai populations.
Autorzy :
Zhao-qian Liu
Jie Liu
Zhi-hua Xiang
Min-yu Hu
Wei Mo
Lian-sheng Wang
Dong-sheng Ou-Yang
Nan He
Dan Wang
Hong-hao Zhou
Pokaż więcej
Temat :
GENETIC polymorphisms
ADRENERGIC receptors
ETHNIC groups
DNA
LEUCOCYTES
POLYMERASE chain reaction
Źródło :
Acta Pharmacologica Sinica; Feb2006, Vol. 27 Issue 2, p254-258, 5p, 2 Black and White Photographs, 2 Charts, 2 Graphs
Terminy geograficzne :
CHINA
Czasopismo naukowe
Tytuł :
Response prediction biomarkers and drug combinations of PARP inhibitors in prostate cancer.
Autorzy :
Chen YX; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China.
Tan LM; Department of Pharmacy, The Second People's Hospital of Huaihua City, Huaihua, 418000, China.
Gong JP; Department of Pharmacy, The Second People's Hospital of Huaihua City, Huaihua, 418000, China.
Huang MS; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China.
Yin JY; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China.
Zhang W; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China.
Zhou HH; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China.
Liu ZQ; Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China. .; Institute of Clinical Pharmacology, Engineering Research Center for Applied Technology of Pharmacogenomics of Ministry of Education, Central South University, Changsha, 410078, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Feb 15. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Hippocampal CysLT 1 R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice.
Autorzy :
Lin JR; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Fang SC; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Tang SS; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Hu M; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Long Y; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Ghosh A; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Sun HB; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Kong LY; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Hong H; Department of Pharmacology, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2017 Apr; Vol. 38 (4), pp. 477-487. Date of Electronic Publication: 2017 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Depression/*drug therapy
Hippocampus/*metabolism
Lipopolysaccharides/*pharmacology
Receptors, Leukotriene/*genetics
Animals ; Chromones/therapeutic use ; Depression/metabolism ; Depression/psychology ; Fluoxetine/therapeutic use ; Gene Knockdown Techniques ; Inflammation/drug therapy ; Inflammation/metabolism ; Leukotriene Antagonists/therapeutic use ; Male ; Mice, Inbred ICR ; Receptors, Leukotriene/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Organic anion transporting polypeptide-1B1 haplotypes in Chinese patients.
Autorzy :
Xu LY; Department of Epidemic and Health Statistics, School of Public Health, Central South University, Changsha 410078, China.
He YJ
Zhang W
Deng S
Li Q
Zhang WX
Liu ZQ
Wang D
Huang YF
Zhou HH
Sun ZQ
Pokaż więcej
Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2007 Oct; Vol. 28 (10), pp. 1693-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Haplotypes*
Polymorphism, Single Nucleotide*
Asian Continental Ancestry Group/*genetics
Organic Anion Transporters/*genetics
Adult ; Alleles ; China ; Gene Frequency ; Humans ; Liver-Specific Organic Anion Transporter 1 ; Male ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length
Czasopismo naukowe
Tytuł :
Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture.
Autorzy :
Liao QC; Nanjing [corrected] Childrens Hospital, Nanjing Medical University, Nanjing 210008, China.
Xiao ZS
Qin YF
Zhou HH
Pokaż więcej
Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2007 Oct; Vol. 28 (10), pp. 1597-602.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Marrow Cells/*drug effects
Cell Differentiation/*drug effects
Core Binding Factor Alpha 1 Subunit/*metabolism
Genistein/*pharmacology
Osteoblasts/*drug effects
p38 Mitogen-Activated Protein Kinases/*metabolism
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Animals ; Blotting, Northern ; Blotting, Western ; Bone Marrow Cells/cytology ; Bone Marrow Cells/metabolism ; Calcium/metabolism ; Cells, Cultured ; Core Binding Factor Alpha 1 Subunit/genetics ; Electrophoretic Mobility Shift Assay ; Female ; Imidazoles/pharmacology ; Integrin-Binding Sialoprotein ; Mice ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteopontin/genetics ; Osteopontin/metabolism ; Phosphorylation/drug effects ; Phytoestrogens/pharmacology ; Protein Binding/drug effects ; Pyridines/pharmacology ; Reverse Transcriptase Polymerase Chain Reaction ; Sialoglycoproteins/genetics ; Sialoglycoproteins/metabolism ; Signal Transduction/drug effects ; Transcription, Genetic/drug effects ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Distributive characteristics of Ser49Gly and Gly389Arg genetic polymorphisms of beta1-adrenoceptor in Chinese Han and Dai populations.
Autorzy :
Liu ZQ; Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Xiang-Ya School of Medicine, Central South University, Changsha 410078, China.
Liu J
Xiang ZH
Hu MY
Mo W
Wang LS
Ou-Yang DS
He N
Wang D
Zhou HH
Pokaż więcej
Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2006 Feb; Vol. 27 (2), pp. 254-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Point Mutation*
Polymorphism, Genetic*
Receptors, Adrenergic, beta-1/*genetics
Adolescent ; Adult ; African Americans/genetics ; Alleles ; Asian Continental Ancestry Group/genetics ; China/ethnology ; Female ; Gene Frequency ; Genotype ; Humans ; Male
Czasopismo naukowe
Tytuł :
Genotype of CYP3AP1 associated with CYP3A activity in Chinese Han population.
Autorzy :
Zhu B; Pharmacogenetics Research Institute, Xiang-Ya School of Medicine, Central South University, Changsha 410078, China.
Chen GL
Chen XP
He N
Liu ZQ
Jiang CH
Wang D
Zhou HH
Pokaż więcej
Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2002 Jun; Vol. 23 (6), pp. 567-72.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aryl Hydrocarbon Hydroxylases/*genetics
Aryl Hydrocarbon Hydroxylases/*metabolism
Midazolam/*blood
Oxidoreductases, N-Demethylating/*metabolism
Adolescent ; Adult ; Asian Continental Ancestry Group/genetics ; Cytochrome P-450 CYP3A ; Ethnic Groups ; Female ; Gene Frequency ; Genotype ; Humans ; Male ; Midazolam/metabolism ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length
Czasopismo naukowe
    Wyświetlanie 1-38 z 38

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