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Tytuł:
CSF Markers of Oxidative Stress Are Associated with Brain Atrophy and Iron Accumulation in a 2-Year Longitudinal Cohort of Early MS.
Autorzy:
Burgetova A; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Dusek P; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.; Department of Neurology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Uher T; Department of Neurology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Vaneckova M; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Vejrazka M; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Burgetova R; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.; Department of Radiology, Third Faculty of Medicine, Charles University, 100 34 Prague, Czech Republic.
Horakova D; Department of Neurology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Srpova B; Department of Neurology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Kalousova M; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Noskova L; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Levova K; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Krasensky J; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Lambert L; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 12; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/diagnostic imaging
Multiple Sclerosis*/pathology
Central Nervous System Diseases*/pathology
Humans ; Prospective Studies ; Longitudinal Studies ; Iron ; Brain/diagnostic imaging ; Brain/pathology ; Magnetic Resonance Imaging/methods ; Oxidative Stress ; Atrophy/pathology ; Gray Matter/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis.
Autorzy:
Andelova M; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic. .
Vodehnalova K; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Krasensky J; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Hardubejova E; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Hrnciarova T; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Srpova B; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Uher T; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Menkyova I; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.; 2nd Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Stastna D; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Friedova L; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Motyl J; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Lizrova Preiningerova J; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Kubala Havrdova E; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Maréchal B; Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Fartaria MJ; Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Kober T; Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland.; Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Horakova D; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, Praha 2, Prague, Czech Republic.
Vaneckova M; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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Źródło:
BMC neurology [BMC Neurol] 2022 Jul 19; Vol. 22 (1), pp. 270. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/diagnostic imaging
Multiple Sclerosis*/pathology
Multiple Sclerosis, Relapsing-Remitting*/diagnostic imaging
Multiple Sclerosis, Relapsing-Remitting*/pathology
Spinal Cord Diseases*/pathology
Brain/pathology ; Brain Stem/diagnostic imaging ; Brain Stem/pathology ; Disability Evaluation ; Humans ; Magnetic Resonance Imaging ; Spinal Cord/diagnostic imaging ; Spinal Cord/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The clinical and paraclinical correlates of employment status in multiple sclerosis.
Autorzy:
Srpova B; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic. .
Sobisek L; Department of Statistics and Probability, University of Economics in Prague, Prague, Czech Republic.
Novotna K; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Uher T; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Friedova L; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Vaneckova M; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
Krasensky J; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
Kubala Havrdova E; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Horakova D; Department of Neurology and Center of Clinical Neuroscience, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2022 Mar; Vol. 43 (3), pp. 1911-1920. Date of Electronic Publication: 2021 Aug 15.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/complications
Cross-Sectional Studies ; Disability Evaluation ; Employment ; Humans ; Magnetic Resonance Imaging ; Neuropsychological Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MxA mRNA decrease preceding NAb detection in IFNβ-treated MS patients.
Autorzy:
Libertinova J; Department of Neurology Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
Meluzinova E; Department of Neurology Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
Matoska V; Laboratory of Molecular Diagnostics Na Homolce Hospital Prague Czech Republic.
Zajac M; Department of Medical Microbiology, Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
Kovarova I; Department of Neurology and Center of Clinical Neuroscience Charles University First Faculty of Medicine and General University Hospital Prague Czech Republic.
Havrdova E; Department of Neurology and Center of Clinical Neuroscience Charles University First Faculty of Medicine and General University Hospital Prague Czech Republic.
Horakova D; Department of Neurology and Center of Clinical Neuroscience Charles University First Faculty of Medicine and General University Hospital Prague Czech Republic.
Tomek A; Department of Neurology Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
Marusic P; Department of Neurology Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
Bojar M; Department of Neurology Charles University 2nd Faculty of Medicine and Motol University Hospital Prague Czech Republic.
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Źródło:
Brain and behavior [Brain Behav] 2017 Feb 09; Vol. 7 (3), pp. e00644. Date of Electronic Publication: 2017 Feb 09 (Print Publication: 2017).
Typ publikacji:
Journal Article; Multicenter Study; Observational Study
MeSH Terms:
Outcome Assessment, Health Care*
Antibodies, Neutralizing/*blood
Interferon-beta/*immunology
Interferon-beta/*pharmacology
Multiple Sclerosis/*blood
Multiple Sclerosis/*drug therapy
Myxovirus Resistance Proteins/*blood
RNA, Messenger/*blood
Adult ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Myxovirus Resistance Protein A mRNA Expression Kinetics in Multiple Sclerosis Patients Treated with IFNβ.
Autorzy:
Libertinova J; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Meluzinova E; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Tomek A; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Horakova D; Department of Neurology and Center of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
Kovarova I; Department of Neurology and Center of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
Matoska V; Laboratory of Molecular Diagnostics, Na Homolce Hospital, Prague, Czech Republic.
Kumstyrova S; Laboratory of Molecular Diagnostics, Na Homolce Hospital, Prague, Czech Republic.
Zajac M; Department of Medical Microbiology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Hyncicova E; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Liskova P; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Houzvickova E; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Martinkovic L; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Bojar M; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Havrdova E; Department of Neurology and Center of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
Marusic P; Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
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Źródło:
PloS one [PLoS One] 2017 Jan 12; Vol. 12 (1), pp. e0169957. Date of Electronic Publication: 2017 Jan 12 (Print Publication: 2017).
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Interferon beta-1a/*therapeutic use
Multiple Sclerosis/*drug therapy
Myxovirus Resistance Proteins/*genetics
Adult ; Aged ; Antibodies, Neutralizing/blood ; Area Under Curve ; Female ; Humans ; Injections, Intramuscular ; Injections, Subcutaneous ; Interferon beta-1a/administration & dosage ; Kinetics ; Male ; Middle Aged ; Multiple Sclerosis/metabolism ; Multiple Sclerosis/pathology ; Myxovirus Resistance Proteins/metabolism ; Prospective Studies ; RNA, Messenger/metabolism ; ROC Curve ; Severity of Illness Index ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Environmental factors associated with disease progression after the first demyelinating event: results from the multi-center SET study.
Autorzy:
Horakova D; Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic.
Zivadinov R
Weinstock-Guttman B
Havrdova E
Qu J
Tamaño-Blanco M
Badgett D
Tyblova M
Bergsland N
Hussein S
Willis L
Krasensky J
Vaneckova M
Seidl Z
Lelkova P
Dwyer MG
Zhang M
Yu H
Duan X
Kalincik T
Ramanathan M
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (1), pp. e53996. Date of Electronic Publication: 2013 Jan 08.
Typ publikacji:
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Multiple Sclerosis/*etiology
Adult ; Antibodies, Viral/blood ; Cohort Studies ; Cytomegalovirus/immunology ; Disease Progression ; Environment ; Epstein-Barr Virus Nuclear Antigens/immunology ; Female ; HLA-DRB1 Chains/genetics ; Humans ; Longitudinal Studies ; Male ; Multiple Sclerosis/immunology ; Multiple Sclerosis/virology ; Prospective Studies ; Risk Factors ; Smoking/adverse effects ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinical correlates of grey matter pathology in multiple sclerosis.
Autorzy:
Horakova D; Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic. dana.horakova@vfn.cz
Kalincik T
Dusankova JB
Dolezal O
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Źródło:
BMC neurology [BMC Neurol] 2012 Mar 07; Vol. 12, pp. 10. Date of Electronic Publication: 2012 Mar 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Brain*/pathology
Brain*/physiopathology
Cognition Disorders*/pathology
Cognition Disorders*/physiopathology
Inflammation*/pathology
Inflammation*/physiopathology
Multiple Sclerosis*/pathology
Multiple Sclerosis*/physiopathology
Atrophy ; Cerebral Cortex/pathology ; Cerebral Cortex/physiopathology ; Disease Progression ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Volumetric MRI markers and predictors of disease activity in early multiple sclerosis: a longitudinal cohort study.
Autorzy:
Kalincik T; Department of Neurology and Center of Clinical Neuroscience, 1st Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic. />Vaneckova M
Tyblova M
Krasensky J
Seidl Z
Havrdova E
Horakova D
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (11), pp. e50101. Date of Electronic Publication: 2012 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Demyelinating Diseases/*diagnosis
Magnetic Resonance Imaging/*methods
Multiple Sclerosis/*diagnosis
Multiple Sclerosis/*pathology
Adult ; Cohort Studies ; Corpus Callosum/pathology ; Czech Republic ; Demyelinating Diseases/drug therapy ; Disease Progression ; Humans ; Interferon-beta/therapeutic use ; Longitudinal Studies ; Middle Aged ; Predictive Value of Tests ; Proportional Hazards Models ; Recurrence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Big Multiple Sclerosis Data network: an international registry research network
Autorzy:
Glaser, Anna
Butzkueven, Helmut
van der Walt, Anneke
Gray, Orla
Spelman, TimAff1, Aff2
Zhu, Chao
Trojano, Maria
Iaffaldano, Pietro
Battaglia, Mario A.Aff7, Aff8
Lucisano, GiuseppeAff6, Aff9
Vukusic, SandraAff10, Aff11, Aff12, Aff13
Vukusic, IrenaAff10, Aff11, Aff12, Aff13
Casey, RomainAff10, Aff11, Aff12, Aff13
Horakova, Dana
Drahota, JiriAff14, Aff15
Magyari, Melinda
Joensen, Hanna
Pontieri, Luigi
Elberling, Frederik
Klyve, Pernilla
Mouresan, Elena Flavia
Forsberg, Lars
Hillert, JanAff1, IDs00415024123036_cor23
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Źródło:
Journal of Neurology. :1-9
Czasopismo naukowe
Szczegóły
Tytuł:
Tract-wise microstructural analysis informs on current and future disability in early multiple sclerosis
Autorzy:
Ravano, VeronicaAff1, Aff2, Aff3, IDs00415023120233_cor1
Piredda, Gian FrancoAff1, Aff2, Aff3
Krasensky, Jan
Andelova, Michaela
Uher, Tomas
Srpova, Barbora
Havrdova, Eva Kubala
Vodehnalova, Karolina
Horakova, Dana
Nytrova, Petra
Disselhorst, Jonathan A.Aff1, Aff2, Aff3
Hilbert, TomAff1, Aff2, Aff3
Maréchal, BénédicteAff1, Aff2, Aff3
Thiran, Jean-PhilippeAff2, Aff3
Kober, TobiasAff1, Aff2, Aff3
Richiardi, Jonas
Vaneckova, Manuela
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Źródło:
Journal of Neurology. 271(2):631-641
Czasopismo naukowe
Szczegóły
Tytuł:
COVID‐19 vaccination and relapse activity: A nationwide cohort study of patients with multiple sclerosis in Denmark.
Autorzy:
Stastna, Dominika
Elberling, Frederik
Pontieri, Luigi
Framke, Elisabeth
Horakova, Dana
Drahota, Jiri
Nytrova, Petra
Magyari, Melinda
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Temat:
COVID-19 vaccines
MULTIPLE sclerosis
COHORT analysis
DISEASE relapse
DANES
Źródło:
European Journal of Neurology; Mar2024, Vol. 31 Issue 3, p1-8, 8p
Terminy geograficzne:
DENMARK
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 165

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