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Wyszukujesz frazę ""Host-Pathogen Interactions"" wg kryterium: Temat


Tytuł:
Fungal resilience and host-pathogen interactions: Future perspectives and opportunities.
Autorzy:
Brown AJP; Medical Research Council Centre for Medical Mycology at the University of Exeter, Exeter, UK.
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Źródło:
Parasite immunology [Parasite Immunol] 2023 Feb; Vol. 45 (2), pp. e12946. Date of Electronic Publication: 2022 Aug 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antifungal Agents*
Host-Pathogen Interactions*
Virulence
Czasopismo naukowe
Tytuł:
Host-pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella .
Autorzy:
Garcia-Bustos V; Department of Internal Medicine and Infectious Diseases, University and Polytechnic La Fe Hospital, Valencia, Spain.; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.; Department of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Pemán J; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.; Department of Medical Microbiology, University and Polytechnic La Fe Hospital, Valencia, Spain.
Ruiz-Gaitán A; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.
Cabañero-Navalon MD; Department of Internal Medicine and Infectious Diseases, University and Polytechnic La Fe Hospital, Valencia, Spain.
Cabanilles-Boronat A; Department of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Fernández-Calduch M; Department of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Marcilla-Barreda L; Department of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Sigona-Giangreco IA; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.; Department of Medical Microbiology, University and Polytechnic La Fe Hospital, Valencia, Spain.
Salavert M; Department of Internal Medicine and Infectious Diseases, University and Polytechnic La Fe Hospital, Valencia, Spain.; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.
Tormo-Mas MÁ; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.
Ruiz-Saurí A; Department of Pathology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 136-146.
Typ publikacji:
Journal Article
MeSH Terms:
Host-Pathogen Interactions*
Candida auris/*physiology
Moths/*immunology
Moths/*microbiology
Animals ; Candida albicans/immunology ; Candida albicans/pathogenicity ; Candida albicans/physiology ; Candida auris/cytology ; Candida auris/immunology ; Candida auris/pathogenicity ; Candida parapsilosis/immunology ; Candida parapsilosis/pathogenicity ; Candida parapsilosis/physiology ; Hemocytes/immunology ; Hemocytes/physiology ; Hemolymph/microbiology ; Immunity ; Larva/microbiology ; Moths/physiology ; Respiratory System/immunology ; Respiratory System/microbiology ; Virulence
Czasopismo naukowe
Tytuł:
CovInter: interaction data between coronavirus RNAs and host proteins.
Autorzy:
Amahong K; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Zhang W; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Zhou Y; State Key Laboratory for Diagnosis and Treatment of Infectious Disease, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang Provincial Key Laboratory for Drug Clinical Research and Evaluation, The First Affiliated Hospital, Zhejiang University, Hangzhou 310000, China.
Zhang S; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.
Yin J; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Li F; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Xu H; Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Yan T; Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Yue Z; Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Liu Y; Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hou T; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.
Qiu Y; State Key Laboratory for Diagnosis and Treatment of Infectious Disease, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang Provincial Key Laboratory for Drug Clinical Research and Evaluation, The First Affiliated Hospital, Zhejiang University, Hangzhou 310000, China.
Tao L; Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Han L; Greater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, Shanghai 315211, China.
Zhu F; College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D546-D556.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coronavirus*/genetics
Coronavirus*/metabolism
Host-Pathogen Interactions*/genetics
RNA, Viral*/genetics
RNA, Viral*/metabolism
Humans ; Coronavirus Infections/metabolism ; Virus Replication ; Databases, Genetic
Czasopismo naukowe
Tytuł:
Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2.
Autorzy:
Guo X; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Cao J; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Cai JP; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Wu J; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Huang J; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.
Asthana P; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Wong SKK; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Ye ZW; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Gurung S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Zhang Y; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Wang S; Respiratory Department, Jinhua Guangfu Hospital, Jinhua, China.
Wang Z; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Ge X; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Kwan HY; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Lyu A; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Chan KM; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.
Wong N; Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, N.T., Hong Kong SAR, China.
Huang J; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Zhou Z; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Bian ZX; Centre for Chinese Herbal Medicine Drug Development Limited, Hong Kong Baptist University, Hong Kong SAR, China.
Yuan S; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. .
Wong HLX; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. .
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Źródło:
Nature communications [Nat Commun] 2022 Dec 23; Vol. 13 (1), pp. 7907. Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiotensin-Converting Enzyme 2*/metabolism
COVID-19*/metabolism
COVID-19*/virology
Matrix Metalloproteinase 14*
SARS-CoV-2*/metabolism
Host-Pathogen Interactions*
Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Peptidyl-Dipeptidase A/metabolism ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe
Tytuł:
SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15.
Autorzy:
Li L; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Luo J; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.; Department of Immunology, School of Basic Medical Sciences, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Zhu Z; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Xu Q; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Wang P; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.; Medical Research Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, P.R. China.
Chang B; Department of Immunology, School of Basic Medical Sciences, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Wang D; Department of Dermatology, Dermatology Hospital of Southern Medical Universitygrid.284723.8, Southern Medical University, Guangzhou, Guangdong, P.R. China.
Yu L; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Lu X; Department of Immunology, School of Basic Medical Sciences, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Zhou J; Department of Immunology, School of Basic Medical Sciences, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Zuo D; Department of Medical Laboratory, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.; Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical Universitygrid.284723.8, Guangzhou, Guangdong, P.R. China.
Chen Q; Medical Research Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, P.R. China.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2022 Dec 21; Vol. 10 (6), pp. e0202822. Date of Electronic Publication: 2022 Nov 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interferon-beta*
Host-Pathogen Interactions*
Animals ; Mice ; Immunity, Innate ; Macrophages/metabolism ; Ubiquitination ; Receptors, Scavenger/genetics ; Receptors, Scavenger/metabolism ; Antiviral Agents ; RNA/metabolism ; Deubiquitinating Enzymes/genetics ; Deubiquitinating Enzymes/metabolism ; Protein Serine-Threonine Kinases/genetics ; Ubiquitin-Specific Proteases/genetics ; Ubiquitin-Specific Proteases/metabolism
Czasopismo naukowe
Tytuł:
Role of pathogen's effectors in understanding host-pathogen interaction.
Autorzy:
Waheed A; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanical Garden, Chinese Academy of Sciences, Turpan 838008, China.
Haxim Y; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanical Garden, Chinese Academy of Sciences, Turpan 838008, China.
Islam W; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Desert Plant Roots Ecology and Vegetation Restoration, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China.
Kahar G; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanical Garden, Chinese Academy of Sciences, Turpan 838008, China.
Liu X; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanical Garden, Chinese Academy of Sciences, Turpan 838008, China.
Zhang D; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Xinjiang Key Laboratory of Conservation and Utilization of Plant Gene Resources, Xinjiang Institute of Ecology & Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanical Garden, Chinese Academy of Sciences, Turpan 838008, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Dec; Vol. 1869 (12), pp. 119347. Date of Electronic Publication: 2022 Aug 30.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*
Plants*
Leucine ; Nucleotides ; Signal Transduction
Czasopismo naukowe
Tytuł:
dRNASb: a systems biology approach to decipher dynamics of host-pathogen interactions using temporal dual RNA-seq data.
Autorzy:
Dinarvand M; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Koch FC; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Al Mouiee D; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, NSW, Australia.
Vuong K; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Vijayan A; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Tanzim AF; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Azad AKM; ProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.
Penesyan A; School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, Australia.
Castaño-Rodríguez N; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Vafaee F; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, NSW, Australia.
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Źródło:
Microbial genomics [Microb Genom] 2022 Sep; Vol. 8 (9).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*/genetics
Systems Biology*
Humans ; RNA-Seq ; Transcriptome ; Virulence/genetics
Czasopismo naukowe
Tytuł:
Editorial: The use of image and imaging flow cytometry as a tool to study host-pathogen interactions.
Autorzy:
Jenner DC; Defence Science Technology Laboratory, CBR Division, Porton Down, Wiltshire, United Kingdom.
Rieger AM; Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.
Porat Z; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Nov 17; Vol. 12, pp. 1069960. Date of Electronic Publication: 2022 Nov 17 (Print Publication: 2022).
Typ publikacji:
Editorial
MeSH Terms:
Diagnostic Imaging*
Host-Pathogen Interactions*
Flow Cytometry
Opinia redakcyjna
Tytuł:
The survival of epidemic and sporadic MRSA on human skin mimics is determined by both host and bacterial factors.
Autorzy:
Baede VO; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Voet MM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
van der Reijden TJK; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
van Wengen A; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Horst-Kreft DE; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Lemmens-den Toom NA; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Tavakol M; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Vos MC; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Nibbering PH; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
van Wamel WJB; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
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Źródło:
Epidemiology and infection [Epidemiol Infect] 2022 Nov 16; Vol. 150, pp. e203. Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Skin*/microbiology
Methicillin-Resistant Staphylococcus aureus*/isolation & purification
Host-Pathogen Interactions*
Humans ; Colony Count, Microbial ; Antimicrobial Peptides/analysis ; Microbial Viability ; Cytokines/analysis ; Chemokines, CC/analysis
Czasopismo naukowe
Tytuł:
Multiple lineages of monkeypox virus detected in the United States, 2021-2022.
Autorzy:
Gigante CM; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Korber B; T-6: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, USA; New Mexico Consortium, Los Alamos, NM, USA.
Seabolt MH; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.; Leidos Inc., Reston, VA 20190, USA.
Wilkins K; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Davidson W; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Rao AK; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Zhao H; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Smith TG; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Hughes CM; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Minhaj F; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Waltenburg MA; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Theiler J; ISR-3: Space Data Science and Systems, Los Alamos National Laboratory, Los Alamos, NM, USA.
Smole S; Massachusetts Department of Public Health, Jamaica Plain, MA, USA.
Gallagher GR; Massachusetts Department of Public Health, Jamaica Plain, MA, USA.
Blythe D; Infectious Disease Epidemiology and Outbreak Response Bureau, Maryland Department of Health, Baltimore, MD, USA.
Myers R; Infectious Disease Epidemiology and Outbreak Response Bureau, Maryland Department of Health, Baltimore, MD, USA.
Schulte J; Dallas County Health and Human Services Public Health Laboratory, Dallas, Texas, USA.
Stringer J; Dallas County Health and Human Services Public Health Laboratory, Dallas, Texas, USA.
Lee P; Florida Department of Health Bureau of Public Health Laboratories-Jacksonville, Jacksonville, FL, USA.
Mendoza RM; Florida Department of Health in Broward County, Hollywood, FL, USA.
Griffin-Thomas LA; Virginia Department of General Services, Division of Consolidated Laboratory Services, Richmond, VA, USA.
Crain J; Virginia Department of Health, Richmond, VA, USA.
Murray J; Utah Department of Health and Human Services, Salt Lake City, UT, USA.
Atkinson A; Utah Department of Health and Human Services, Salt Lake City, UT, USA.
Gonzalez AH; Sacramento County Public Health, Sacramento, CA, USA.
Nash J; Sacramento County Public Health, Sacramento, CA, USA.
Batra D; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Damon I; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
McQuiston J; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Hutson CL; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
McCollum AM; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Li Y; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Nov 04; Vol. 378 (6619), pp. 560-565. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Monkeypox*/enzymology
Monkeypox*/virology
Monkeypox virus*/genetics
Monkeypox virus*/isolation & purification
APOBEC Deaminases*/metabolism
Host-Pathogen Interactions*
RNA Editing*
Humans ; Nigeria/epidemiology ; United States/epidemiology ; Mutation ; Evolution, Molecular ; Adenosine/genetics ; Cytidine/genetics
Czasopismo naukowe
Tytuł:
Host-Pathogen Interaction 3.0.
Autorzy:
Burkovski A; Microbiology Division, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 24; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Editorial
MeSH Terms:
Host-Pathogen Interactions*
Plants*
Humans ; Animals
Opinia redakcyjna
Tytuł:
Disease outbreaks select for mate choice and coat color in wolves.
Autorzy:
Cubaynes S; CEFE, University of Montpellier, CNRS, EPHE-PSL University, IRD, 34090 Montpellier, France.
Brandell EE; Center for Infectious Disease Dynamics, Department of Biology, Pennsylvania State University, State College, PA 16802, USA.
Stahler DR; Yellowstone Center for Resources, Yellowstone National Park, WY 82190, USA.
Smith DW; Yellowstone Center for Resources, Yellowstone National Park, WY 82190, USA.
Almberg ES; Wildlife Division, Montana Fish Wildlife & Park, Bozeman, MT 59718, USA.
Schindler S; School of Biological Sciences, University of Bristol, Bristol BS8 1QU, UK.
Wayne RK; Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Dobson AP; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.; Santa Fe Institute, Santa Fe, NM 87501, USA.
vonHoldt BM; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
MacNulty DR; Department of Wildland Resources and Ecology Center, Utah State University, Logan, UT 84322, USA.
Cross PC; US Geological Survey, Northern Rocky Mountain Science Center, Bozeman, MT 59715, USA.
Hudson PJ; Center for Infectious Disease Dynamics, Department of Biology, Pennsylvania State University, State College, PA 16802, USA.
Coulson T; Department of Biology, University of Oxford, Oxford OX1 3SZ, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Oct 21; Vol. 378 (6617), pp. 300-303. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Outbreaks*
Distemper Virus, Canine*
Wolves*/genetics
Wolves*/virology
Mating Preference, Animal*
Distemper*/epidemiology
Distemper*/genetics
Host-Pathogen Interactions*/genetics
Sexual Selection*
Hair Color*/genetics
Animals ; Cross-Sectional Studies ; North America ; Prevalence ; Alleles
Czasopismo naukowe
Tytuł:
Editorial: Pathogenic microbes: Multi-omics analysis of host-pathogen interactions and immune regulation.
Autorzy:
Wang X; Guangdong Qingyunshan Pharmaceutical Co., Ltd., Shaoguan, China.
Yu J; Guangdong Qingyunshan Pharmaceutical Co., Ltd., Shaoguan, China.
Zhang X; Department of Food Science and Engineering, Ningbo University, Ningbo, China.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Oct 18; Vol. 12, pp. 1053792. Date of Electronic Publication: 2022 Oct 18 (Print Publication: 2022).
Typ publikacji:
Editorial; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*
Yersinia*
Raport
Tytuł:
Biting the hand that feeds: Metabolic determinants of cell fate during infection.
Autorzy:
Fraschilla I; Program in Immunology, Harvard Medical School, Boston, MA, United States.
Evavold CL; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Oct 13; Vol. 13, pp. 923024. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity, Innate*
Host-Pathogen Interactions*
Animals ; Ligands ; Cell Differentiation ; Inflammasomes ; Mammals
Czasopismo naukowe
Tytuł:
Spatially structured eco-evolutionary dynamics in a host-pathogen interaction render isolated populations vulnerable to disease.
Autorzy:
Höckerstedt L; Organismal and Evolutionary Biology Research Program, Faculty of Biological and Environmental Sciences, 00014 University of Helsinki, Helsinki, Finland.; Finnish Meteorological Institute, FI-00101, Helsinki, Finland.
Numminen E; Organismal and Evolutionary Biology Research Program, Faculty of Biological and Environmental Sciences, 00014 University of Helsinki, Helsinki, Finland.
Ashby B; Department of Integrative Biology, University of California, Berkeley, CA, 94720, USA.; Department of Mathematics, Simon Fraser University, Burnaby, BC, V3H 5J5, Canada.
Boots M; Department of Integrative Biology, University of California, Berkeley, CA, 94720, USA.; Biosciences, University of Exeter, Penryn, TR10 9EZ, UK.
Norberg A; Department of Evolutionary Biology and Environmental Studies, University of Zürich, CH-8057, Zurich, Switzerland.
Laine AL; Organismal and Evolutionary Biology Research Program, Faculty of Biological and Environmental Sciences, 00014 University of Helsinki, Helsinki, Finland. .; Department of Evolutionary Biology and Environmental Studies, University of Zürich, CH-8057, Zurich, Switzerland. .
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Źródło:
Nature communications [Nat Commun] 2022 Oct 13; Vol. 13 (1), pp. 6018. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Biological Evolution*
Host-Pathogen Interactions*/genetics
Humans ; Population Dynamics
Czasopismo naukowe
Tytuł:
The buried gems of disease tolerance in animals: Evolutionary and interspecies comparative approaches: Interspecies comparative approaches are valuable tools for exploring potential new mechanisms of disease tolerance in animals: Interspecies comparative approaches are valuable tools for exploring potential new mechanisms of disease tolerance in animals.
Autorzy:
Hawash MBF; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.; Biochemistry and Molecular Biomedicine Department, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
El-Deeb MA; Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.
Gaber R; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
Morsy KS; Biology Department, College of Science, King Khalid University, Abha, Saudi Arabia.
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Źródło:
BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2022 Oct; Vol. 44 (10), pp. e2200080. Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Evolution*
Host-Pathogen Interactions*
Animals ; Immune Tolerance ; Mammals/genetics ; Mice
Czasopismo naukowe
Tytuł:
Understanding pathogen survival and transmission by arthropod vectors to prevent human disease.
Autorzy:
Barillas-Mury C; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, MD 20852, USA.
Ribeiro JMC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, MD 20852, USA.
Valenzuela JG; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, MD 20852, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Sep 30; Vol. 377 (6614), pp. eabc2757. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Arthropod Vectors*/microbiology
Arthropod Vectors*/parasitology
Host-Pathogen Interactions*
Salivary Proteins and Peptides*/metabolism
Vector Borne Diseases*/prevention & control
Vector Borne Diseases*/transmission
Animals ; Humans ; Leishmaniasis/prevention & control ; Leishmaniasis/transmission ; Malaria/prevention & control ; Malaria/transmission
Czasopismo naukowe
Tytuł:
Analysis of Host-Bacteria Protein Interactions Reveals Conserved Domains and Motifs That Mediate Fundamental Infection Pathways.
Autorzy:
Gómez Borrego J; Systems Biology of Infection Laboratory, Department of Biochemistry and Molecular Biology, Biosciences Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
Torrent Burgas M; Systems Biology of Infection Laboratory, Department of Biochemistry and Molecular Biology, Biosciences Faculty, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 29; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Host-Pathogen Interactions*
Proteins*
Databases, Protein ; Host Microbial Interactions ; Humans ; Protein Interaction Mapping/methods
Czasopismo naukowe
Tytuł:
Coronaviruses exploit a host cysteine-aspartic protease for replication.
Autorzy:
Chu H; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China. .
Hou Y; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Yang D; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Wen L; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Shuai H; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Yoon C; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Shi J; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Chai Y; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Yuen TT; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Hu B; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Li C; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Zhao X; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Wang Y; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Huang X; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Lee KS; Transgenic Core Facility, Centre for Comparative Medicine Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Luo C; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Cai JP; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Poon VK; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Chan CC; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Zhang AJ; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Yuan S; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Sit KY; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Foo DC; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Au WK; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Wong KK; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Zhou J; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Kok KH; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.
Jin DY; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.; Guangzhou Laboratory, Guangzhou, China.
Chan JF; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China. .; Guangzhou Laboratory, Guangzhou, China. .; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Microbiology, Queen Mary Hospital, Pokfulam, China. .; Academician Workstation of Hainan Province, Hainan Medical University, Haikou, China. .; Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, The University of Hong Kong, Pokfulam, China. .
Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, China. .; Guangzhou Laboratory, Guangzhou, China. .; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China. .; Department of Microbiology, Queen Mary Hospital, Pokfulam, China. .; Academician Workstation of Hainan Province, Hainan Medical University, Haikou, China. .; Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, The University of Hong Kong, Pokfulam, China. .
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Źródło:
Nature [Nature] 2022 Sep; Vol. 609 (7928), pp. 785-792. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Aspartic Acid*/metabolism
Caspase 6*/metabolism
Coronavirus*/growth & development
Coronavirus*/pathogenicity
Coronavirus Infections*/enzymology
Coronavirus Infections*/virology
Cysteine*/metabolism
Host-Pathogen Interactions*
Virus Replication*
Animals ; Apoptosis ; Coronavirus Nucleocapsid Proteins/immunology ; Coronavirus Nucleocapsid Proteins/metabolism ; Cricetinae ; Dipeptidyl Peptidase 4/genetics ; Dipeptidyl Peptidase 4/metabolism ; Humans ; Interferons/antagonists & inhibitors ; Interferons/immunology ; Lung/pathology ; Mesocricetus ; Mice ; Middle East Respiratory Syndrome Coronavirus ; Severe acute respiratory syndrome-related coronavirus ; SARS-CoV-2 ; Survival Rate ; Weight Loss
Czasopismo naukowe
Tytuł:
Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways.
Autorzy:
N'Gadjaga MD; Institut Pasteur, CNRS UMR3691, Cellular Biology of Microbial Infection, Université Paris Cité, Paris, France; Sorbonne Université, Collège Doctoral, Paris, France.
Perrinet S; Institut Pasteur, CNRS UMR3691, Cellular Biology of Microbial Infection, Université Paris Cité, Paris, France.
Connor MG; Institut Pasteur, Chromatin and Infection, Université Paris Cité, Paris, France.
Bertolin G; CNRS, IGDR (Institute of Genetics and Development of Rennes), UMR 6290, Univ Rennes, Rennes, France.
Millot GA; Institut Pasteur, Hub Bioinformatique et Biostatistique-DBC, Université Paris Cité, Paris, France.
Subtil A; Institut Pasteur, CNRS UMR3691, Cellular Biology of Microbial Infection, Université Paris Cité, Paris, France. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102338. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chlamydia Infections*/metabolism
Chlamydia Infections*/microbiology
Chlamydia trachomatis*/growth & development
Chlamydia trachomatis*/metabolism
Epithelial Cells*/metabolism
Epithelial Cells*/microbiology
Glycolysis*
Host-Pathogen Interactions*
Oxidative Phosphorylation*
Adenosine Triphosphate/metabolism ; Glucose/metabolism ; HeLa Cells ; Humans
Czasopismo naukowe

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