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Wyświetlanie 1-9 z 9
Tytuł :
Synthesis and Metabolism of BTN3A1 Ligands: Studies on Modifications of the Allylic Alcohol.
Autorzy :
Lentini NA; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Schroeder CM; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Harmon NM; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Huang X; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092,United States.
Schladetsch MA; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092,United States.
Foust BJ; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Poe MM; Department of Chemistry, Western Michigan University, Kalamazoo, Michigan 49008-5413, United States.
Hsiao CC; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092,United States.
Wiemer AJ; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092,United States.; Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Wiemer DF; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.; Department of Pharmacology, University of Iowa, Iowa City, Iowa 52242-1109, United States.
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Źródło :
ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Dec 04; Vol. 12 (1), pp. 136-142. Date of Electronic Publication: 2020 Dec 04 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis and Bioactivity of the Alanyl Phosphonamidate Stereoisomers Derived from a Butyrophilin Ligand.
Autorzy :
Lentini NA; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Hsiao CC; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Crull GB; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Wiemer AJ; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, United States.; Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Wiemer DF; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.; Department of Pharmacology, University of Iowa, Iowa City, Iowa 52242-1109, United States.
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Źródło :
ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Aug 06; Vol. 10 (9), pp. 1284-1289. Date of Electronic Publication: 2019 Aug 06 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Probing the Ligand-Binding Pocket of BTN3A1.
Autorzy :
Poe MM
Agabiti SS
Liu C
Li V
Teske KA; Department of Chemistry , Western Michigan University , Kalamazoo , Michigan 49008 , United States.
Hsiao CC
Wiemer AJ
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2019 Jul 25; Vol. 62 (14), pp. 6814-6823. Date of Electronic Publication: 2019 Jul 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
Butyrophilins/*metabolism
Organophosphonates/*chemistry
Organophosphonates/*pharmacology
Antigens, CD/chemistry ; Binding Sites/drug effects ; Butyrophilins/chemistry ; Drug Design ; Humans ; Ligands ; Molecular Docking Simulation ; Protein Domains/drug effects ; Structure-Activity Relationship ; T-Lymphocytes/cytology ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation.
Autorzy :
Lentini NA; Department of Chemistry , University of Iowa , Iowa City , Iowa 52242-1294 , United States.
Foust BJ; Department of Chemistry , University of Iowa , Iowa City , Iowa 52242-1294 , United States.
Hsiao CC; Department of Pharmaceutical Sciences , University of Connecticut , Storrs , Connecticut 06269-3092 , United States.
Wiemer AJ; Department of Pharmaceutical Sciences , University of Connecticut , Storrs , Connecticut 06269-3092 , United States.; Institute for Systems Genomics , University of Connecticut , Storrs , Connecticut 06269-3092 , United States.
Wiemer DF; Department of Chemistry , University of Iowa , Iowa City , Iowa 52242-1294 , United States.; Department of Pharmacology , University of Iowa , Iowa City , Iowa 52242-1109 , United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2018 Oct 11; Vol. 61 (19), pp. 8658-8669. Date of Electronic Publication: 2018 Sep 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Survival*
Butyrophilins/*metabolism
Lymphocyte Activation/*immunology
Organophosphorus Compounds/*chemistry
Plasma/*chemistry
Prodrugs/*pharmacology
T-Lymphocytes/*immunology
Butyrophilins/chemistry ; Drug Stability ; Humans ; Interferon-gamma/metabolism ; K562 Cells ; Ligands ; Prodrugs/chemistry ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Cross-Coupling of Amides with Alkylboranes via Nickel-Catalyzed C-N Bond Cleavage.
Autorzy :
Liu X; RWTH Aachen University, Institute of Organic Chemistry , Landoltweg 1 , 52074 Aachen , Germany.
Hsiao CC; RWTH Aachen University, Institute of Organic Chemistry , Landoltweg 1 , 52074 Aachen , Germany.
Guo L; RWTH Aachen University, Institute of Organic Chemistry , Landoltweg 1 , 52074 Aachen , Germany.
Rueping M; RWTH Aachen University, Institute of Organic Chemistry , Landoltweg 1 , 52074 Aachen , Germany.; King Abdullah University of Science and Technology (KAUST), Kaust Catalysis Center (KCC) , Thuwal 23955-6900 , Saudi Arabia.
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Źródło :
Organic letters [Org Lett] 2018 May 18; Vol. 20 (10), pp. 2976-2979. Date of Electronic Publication: 2018 May 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Mixed Aryl Phosphonate Prodrugs of a Butyrophilin Ligand.
Autorzy :
Foust BJ; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Poe MM; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092 United States.
Lentini NA; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.
Hsiao CC; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092 United States.
Wiemer AJ; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092 United States.; Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut 06269-3092, United States.
Wiemer DF; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, United States.; Department of Pharmacology, University of Iowa, Iowa City, Iowa 52242-1109, United States.
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Źródło :
ACS medicinal chemistry letters [ACS Med Chem Lett] 2017 Aug 09; Vol. 8 (9), pp. 914-918. Date of Electronic Publication: 2017 Aug 09 (Print Publication: 2017).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.
Autorzy :
Shippy RR; Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States.
Lin X; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Agabiti SS; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Li J; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Zangari BM; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Foust BJ; Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States.
Poe MM; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Hsiao CC; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Vinogradova O; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.
Wiemer DF; Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States.
Wiemer AJ; Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States.; Institute for Systems Genomics, University of Connecticut , Storrs, Connecticut 06269, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2017 Mar 23; Vol. 60 (6), pp. 2373-2382. Date of Electronic Publication: 2017 Mar 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
Butyrophilins/*agonists
Butyrophilins/*metabolism
Organophosphonates/*chemistry
Organophosphonates/*pharmacology
Prodrugs/*chemistry
Prodrugs/*pharmacology
Cell Line ; Humans ; K562 Cells ; Lymphocyte Activation/drug effects ; Molecular Docking Simulation ; Phosphines/chemistry ; Phosphines/pharmacology ; T-Lymphocytes/drug effects
Czasopismo naukowe
Tytuł :
Zinc ion enhances GABA tea-mediated oxidative DNA damage.
Autorzy :
Chuang SM; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, Republic of China.
Wang HF
Hsiao CC
Cherng SH
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2012 Feb 15; Vol. 60 (6), pp. 1586-94. Date of Electronic Publication: 2012 Feb 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*/drug effects
Tea/*chemistry
Zinc/*pharmacology
gamma-Aminobutyric Acid/*administration & dosage
Antioxidants/pharmacology ; Bacteriophage phi X 174/genetics ; Catalase/pharmacology ; Catechin/analogs & derivatives ; Catechin/pharmacology ; Comet Assay ; DNA, Viral/drug effects ; Glutathione/pharmacology ; Humans ; Hydrogen Peroxide/pharmacology ; Lymphocytes ; Oxidants/pharmacology ; Oxidation-Reduction ; Potassium Iodide/pharmacology
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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