Autor: "Hsiao FP" - OpacWWW

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Tytuł:: Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Autorzy:: Lin FY; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsiao FP; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.
Huang CY; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Shih CM; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Tsao NW; Division of Cardiovascular Surgery, Taipei Medical University Hospital, Taipei, Taiwan.
Tsai CS; Division of Cardiovascular Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Yang SF; Department of Dentistry, National Yang-Ming University, Taipei, Taiwan; Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chang NC; Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan; Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hung SL; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan; Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan.
Lin YW; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Institute of Oral Biology, National Yang-Ming University, Taipei, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Jul 24; Vol. 9 (7), pp. e102450. Date of Electronic Publication: 2014 Jul 24 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alveolar Bone Loss/*microbiology
Bacterial Proteins/*genetics
Chaperonin 60/*genetics
Osteoclasts/*pathology
Periodontal Ligament/*microbiology
Periodontitis/*microbiology
Alveolar Bone Loss/genetics ; Alveolar Bone Loss/metabolism ; Alveolar Bone Loss/pathology ; Animals ; Bacterial Proteins/metabolism ; Bacterial Proteins/pharmacology ; Chaperonin 60/metabolism ; Chaperonin 60/pharmacology ; Gene Expression Regulation ; Host-Pathogen Interactions ; Humans ; Integrin alpha1/genetics ; Integrin alpha1/metabolism ; Integrin alpha2/genetics ; Integrin alpha2/metabolism ; Interleukin-6/biosynthesis ; Interleukin-6/metabolism ; Interleukin-8/biosynthesis ; Interleukin-8/metabolism ; Male ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Osteoclasts/drug effects ; Osteoclasts/metabolism ; Periodontal Ligament/pathology ; Periodontitis/genetics ; Periodontitis/metabolism ; Periodontitis/pathology ; Porphyromonas gingivalis/genetics ; Porphyromonas gingivalis/metabolism ; Porphyromonas gingivalis/pathogenicity ; RANK Ligand/genetics ; RANK Ligand/metabolism ; Rats ; Rats, Sprague-Dawley ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Recombinant Proteins/pharmacology

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