Autor: "Huang H" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The Role of Interferon Regulatory Factor 1 in Regulating Microglial Activation and Retinal Inflammation.
Autorzy:: Yang X; Department of Ophthalmology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.; Aier Eye Hospital Group, Aier Eye Institute, Changsha 410015, China.
Diaz V; Department of Ophthalmology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Huang H; Department of Ophthalmology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 24; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:: Journal Article
MeSH Terms:: Inflammation*/pathology
Interferon Regulatory Factor-1*/genetics
Interferon Regulatory Factor-1*/metabolism
Microglia*/metabolism
Animals ; Humans ; Mice ; Rats ; Lipopolysaccharides ; Retina/pathology

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Skocz do pozycji: 2.

Tytuł:: Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism.
Autorzy:: Zhang Y; NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing, People's Republic of China.
Ran Y; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Kong L; School of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Geng L; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Huang H; NHC Key Laboratory of Birth Defects and Reproductive Health, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing, People's Republic of China.
Zhang H; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Hu J; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Qi H; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Chen Y; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of ovarian research [J Ovarian Res] 2021 Jul 20; Vol. 14 (1), pp. 97. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing/*metabolism
Inflammation/*drug therapy
Metformin/*therapeutic use
Polycystic Ovary Syndrome/*drug therapy
Adult ; Case-Control Studies ; Female ; Humans ; Metformin/pharmacology ; Retrospective Studies

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Skocz do pozycji: 3.

Tytuł:: Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Autorzy:: Huang H; Department of Orthopaedics, Qujing First People's Hospital, Qujing, Yunnan 655000, P.R. China.
Liu K; Department of Orthopaedics, Qujing First People's Hospital, Qujing, Yunnan 655000, P.R. China.
Ou H; Department of Orthopaedics, Qujing First People's Hospital, Qujing, Yunnan 655000, P.R. China.
Qian X; Department of Orthopaedics, Qujing First People's Hospital, Qujing, Yunnan 655000, P.R. China.
Wan J; Department of Orthopaedics, Qujing First People's Hospital, Qujing, Yunnan 655000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 13.
Typ publikacji:: Journal Article
MeSH Terms:: Chondrocytes/*metabolism
Inflammation/*metabolism
Interleukin-1beta/*metabolism
Oxidative Stress/*drug effects
Phosphoglycerate Dehydrogenase/*metabolism
Phosphoglycerate Dehydrogenase/*pharmacology
Animals ; Apoptosis/drug effects ; Kelch-Like ECH-Associated Protein 1/metabolism ; Male ; Matrix Metalloproteinase 13/metabolism ; NF-E2-Related Factor 2/metabolism ; Osteoarthritis/metabolism ; Phosphoglycerate Dehydrogenase/genetics ; Rats ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 4.

Tytuł:: Cold-inducible RNA-binding protein (CIRP) in inflammatory diseases: Molecular insights of its associated signalling pathways.
Autorzy:: Zhong P; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Cardiovascular Research Institute of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Cardiology, Wuhan, China.
Peng J; Department of Cardiovascular Medicine, The second Affiliated Hospital of University of South China, Hengyang, China.
Yuan M; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Cardiovascular Research Institute of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Cardiology, Wuhan, China.
Kong B; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Cardiovascular Research Institute of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Cardiology, Wuhan, China.
Huang H; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Cardiovascular Research Institute of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Cardiology, Wuhan, China.; Pokaż więcej
Źródło:: Scandinavian journal of immunology [Scand J Immunol] 2021 Jan; Vol. 93 (1), pp. e12949. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Disease Susceptibility*
Signal Transduction*
Inflammation/*etiology
Inflammation/*metabolism
RNA-Binding Proteins/*genetics
RNA-Binding Proteins/*metabolism
Animals ; Biomarkers ; Humans ; Inflammation/drug therapy ; Inflammation/pathology ; Lymphocyte Antigen 96/metabolism ; Molecular Targeted Therapy ; Multiprotein Complexes/metabolism ; Peptide Fragments/metabolism ; Peptide Fragments/pharmacology ; Protein Binding ; RNA-Binding Proteins/chemistry ; Receptors, Interleukin-6/metabolism ; Toll-Like Receptor 2/metabolism ; Triggering Receptor Expressed on Myeloid Cells-1/metabolism

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Skocz do pozycji: 5.

Tytuł:: Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide.
Autorzy:: Yan L; Department of Nephrology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Jiaqiong L; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Yue G; Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoyong L; Department of General Surgery, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Xuexian T; Department of Pathology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Ming L; Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yinglan L; Department of Endocrine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xinxue L; Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zena H; Department of General Medicine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Pokaż więcej
Źródło:: Renal failure [Ren Fail] 2020 Nov; Vol. 42 (1), pp. 270-281.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Kidney Injury/*chemically induced
Acute Kidney Injury/*prevention & control
Atorvastatin/*pharmacology
Hydrogen Sulfide/*metabolism
Inflammation/*metabolism
Acute Kidney Injury/pathology ; Animals ; Apoptosis/drug effects ; Contrast Media/adverse effects ; Cystathionine beta-Synthase/metabolism ; Cystathionine gamma-Lyase/metabolism ; Disease Models, Animal ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Male ; Oxidative Stress/drug effects ; Protective Agents/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sulfides ; Up-Regulation/drug effects

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Skocz do pozycji: 6.

Tytuł:: Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis.
Autorzy:: Saddala MS; Department of Ophthalmology, School of Medicine, University of Missouri-Columbia, 1 Hospital Drive, MA102C, Columbia, MO, 65212, USA.
Lennikov A; Department of Ophthalmology, School of Medicine, University of Missouri-Columbia, 1 Hospital Drive, MA102C, Columbia, MO, 65212, USA.
Mukwaya A; Department of Ophthalmology, Institute for Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Yang Y; Dalton Cardiovascular Research Center, University of Missouri-Columbia, Columbia, MO, USA.
Hill MA; Dalton Cardiovascular Research Center, University of Missouri-Columbia, Columbia, MO, USA.
Lagali N; Department of Ophthalmology, Institute for Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Huang H; Department of Ophthalmology, School of Medicine, University of Missouri-Columbia, 1 Hospital Drive, MA102C, Columbia, MO, 65212, USA. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2020 Apr 25; Vol. 17 (1), pp. 132. Date of Electronic Publication: 2020 Apr 25.
Typ publikacji:: Journal Article
MeSH Terms:: Calcium Channel Blockers/*pharmacology
Calcium Channels, L-Type/*drug effects
Inflammation/*prevention & control
Microglia/*drug effects
Neovascularization, Pathologic/*prevention & control
Animals ; Anti-Inflammatory Agents/pharmacology ; Drug Discovery ; Inflammation/metabolism ; Mice ; Microglia/metabolism ; Molecular Docking Simulation ; Neovascularization, Pathologic/metabolism

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Skocz do pozycji: 7.

Tytuł:: ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis.
Autorzy:: Shangxun Z; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Junjie L; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Wei Z; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Yutong W; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Wenyuan J; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Shanshou L; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Yanjun W; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Qianmei W; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Zhusheng F; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Chaoping Y; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Ran Z; Department of Immunology, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Wen Y; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.
Yang H; Department of Emergency, Xijing Hospital, Fourth Military Medical University, #169 Changle Xi Road, Xi'an, Shaanxi Province, China 710032.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2020 Mar 24; Vol. 2020, pp. 9607535. Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Deaminase/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
MicroRNAs/*metabolism
Sepsis/*metabolism
Suppressor of Cytokine Signaling 3 Protein/*metabolism
Adenosine Deaminase/genetics ; Animals ; Blotting, Western ; Immunoprecipitation ; Inflammation/genetics ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/genetics ; RAW 264.7 Cells ; Sepsis/genetics ; Suppressor of Cytokine Signaling 3 Protein/genetics

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Skocz do pozycji: 8.

Tytuł:: Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p.
Autorzy:: Mei L; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
He M; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Zhang C; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Miao J; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Wen Q; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China.
Liu X; School of Basic Medical Sciences, Guiyang University of Chinese Medicine, Guiyang, Guizhou Province, 550025, China.
Xu Q; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Ye S; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Ye P; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Huang H; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Lin J; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Zhou X; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Zhao K; School of Nursing Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Chen D; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Zhou J; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Li C; School of Nursing Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
Li H; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Dec 18; Vol. 9 (1), pp. 19370. Date of Electronic Publication: 2019 Dec 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetophenones/*pharmacology
HMGB1 Protein/*genetics
Inflammation/*drug therapy
MicroRNAs/*genetics
Sepsis/*drug therapy
Acetophenones/chemistry ; Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Disease Models, Animal ; Drugs, Chinese Herbal/chemistry ; Gene Expression Regulation/drug effects ; Humans ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/pathology ; Lipopolysaccharides/toxicity ; Mice ; NF-kappa B/genetics ; Paeonia/chemistry ; RAW 264.7 Cells ; Sepsis/genetics ; Sepsis/pathology

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Skocz do pozycji: 9.

Tytuł:: Effects of depression on healing and inflammatory responses of acute wounds in rats.
Autorzy:: Jian J; Department of Burn and Plastic Surgery, 903 Hospital of PLA, Hangzhou, 313000, Zhengjiang Province, China.
Yi-Heng H; Pharmacy College, Fudan University, Shanghai, 200433, China.
Bang-Hui Z; Department of Burns, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, 200433, China.
Jian-Hua C; Shanghai Key Laboratory of Psychotic Disorders, Shanghai, 200433, China.
Xu-Dong Z; Department of Burn and Plastic Surgery, 903 Hospital of PLA, Hangzhou, 313000, Zhengjiang Province, China.
Shi-Chu X; Department of Burns, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, 200433, China.
Peng-Fei L; Department of Burns, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, 200433, China.
Xiao-Yan H; Department of Burns, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, 200433, China.
Zhao-Fan X; Department of Burns, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, 200433, China.; Pokaż więcej
Źródło:: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2019 Sep; Vol. 27 (5), pp. 462-469. Date of Electronic Publication: 2019 Jun 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytokines/*metabolism
Depression/*pathology
Inflammation/*pathology
Soft Tissue Injuries/*pathology
Wound Healing/*physiology
Animals ; Depression/immunology ; Disease Models, Animal ; Inflammation/immunology ; Rats ; Soft Tissue Injuries/immunology ; Wound Healing/immunology

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Skocz do pozycji: 10.

Tytuł:: Association between dietary inflammatory index and bone density in lactating women at 6 months postpartum: a longitudinal study.
Autorzy:: Zhou Y; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, NO.38 Xueyuan Road, Beijing, 100083, China.
Zhu X; Beijing Northern Hospital, NO.10 Chedaogou Road, Beijing, China.
Zhang M; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, NO.38 Xueyuan Road, Beijing, 100083, China.
Li Y; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, NO.38 Xueyuan Road, Beijing, 100083, China.
Liu W; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, NO.38 Xueyuan Road, Beijing, 100083, China.
Huang H; Beijing Northern Hospital, NO.10 Chedaogou Road, Beijing, China.
Xu Y; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, NO.38 Xueyuan Road, Beijing, 100083, China. .; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing, NO.38 Xueyuan Road, Beijing, 100083, China. .; Pokaż więcej
Źródło:: BMC public health [BMC Public Health] 2019 Aug 09; Vol. 19 (1), pp. 1076. Date of Electronic Publication: 2019 Aug 09.
Typ publikacji:: Journal Article
MeSH Terms:: Bone Density/*physiology
Diet/*adverse effects
Inflammation/*physiopathology
Lactation/*physiology
Adult ; China ; Female ; Humans ; Longitudinal Studies ; Postpartum Period ; Prospective Studies

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Skocz do pozycji: 11.

Tytuł:: The Anti-Inflammatory Effects of CXCR5 in the Mice Retina following Ischemia-Reperfusion Injury.
Autorzy:: Cao X; Aier School of Ophthalmology, Central South University, Aier Eye Institute, Changsha, Hunan, China.; Department of Ophthalmology, Changsha Aier Eye Hospital, Changsha, Hunan, China.
Li W; Aier School of Ophthalmology, Central South University, Aier Eye Institute, Changsha, Hunan, China.; Department of Ophthalmology, Hunan Children' Hospital, Changsha, Hunan, China.
Liu Y; Department of Ophthalmology, Changsha Aier Eye Hospital, Changsha, Hunan, China.
Huang H; Mason Eye Institute, Department of Ophthalmology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Ye CH; Aier School of Ophthalmology, Central South University, Aier Eye Institute, Changsha, Hunan, China.; Department of Ophthalmology, Changsha Aier Eye Hospital, Changsha, Hunan, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2019 Jul 04; Vol. 2019, pp. 3487607. Date of Electronic Publication: 2019 Jul 04 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Inflammation/*genetics
Receptors, CXCR5/*genetics
Reperfusion Injury/*genetics
Retina/*metabolism
Animals ; Calcium-Binding Proteins/genetics ; Chemokine CXCL13/genetics ; Gene Expression Regulation/genetics ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Intraocular Pressure/genetics ; Mice ; Mice, Knockout ; Microfilament Proteins/genetics ; Reperfusion Injury/metabolism ; Reperfusion Injury/physiopathology ; Retina/pathology

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Skocz do pozycji: 12.

Tytuł:: Callistephin enhances the protective effects of isoflurane on microglial injury through downregulation of inflammation and apoptosis.
Autorzy:: Zhao L; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Chen S; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Liu T; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Wang X; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Huang H; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Liu W; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Jul; Vol. 20 (1), pp. 802-812. Date of Electronic Publication: 2019 May 22.
Typ publikacji:: Journal Article
MeSH Terms:: Anthocyanins/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Apoptosis/*drug effects
Inflammation/*drug therapy
Isoflurane/*pharmacology
Microglia/*drug effects
Animals ; Antioxidants/pharmacology ; Cell Line ; Inflammation/immunology ; Lipopolysaccharides/immunology ; Mice ; Microglia/immunology ; Nitric Oxide/immunology ; Phagocytosis/drug effects ; Reactive Oxygen Species/immunology

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Skocz do pozycji: 13.

Tytuł:: Withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice.
Autorzy:: Yan X; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Huang G; b Department of Neurosurgery , The First Affiliated Hospital of Guangxi Medical University , Nanning , China.
Liu Q; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Zheng J; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Chen H; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Huang Q; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Chen J; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.
Huang H; a Department of Neurosurgery , the Fourth Affiliated Hospital of Guangxi Medical University , Liuzhou , China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2017 Dec; Vol. 55 (1), pp. 1171-1176.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Apoptosis/*drug effects
Inflammation/*prevention & control
Neuroprotective Agents/*pharmacology
Spinal Cord/*drug effects
Spinal Cord Injuries/*drug therapy
Withanolides/*pharmacology
Animals ; Apoptosis Regulatory Proteins/metabolism ; Behavior, Animal/drug effects ; Brain-Derived Neurotrophic Factor/metabolism ; Disease Models, Animal ; Glial Cell Line-Derived Neurotrophic Factor/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/physiopathology ; Inflammation Mediators/metabolism ; Mice, Inbred BALB C ; Motor Activity/drug effects ; Nogo Proteins/metabolism ; Signal Transduction/drug effects ; Spinal Cord/metabolism ; Spinal Cord/pathology ; Spinal Cord/physiopathology ; Spinal Cord Injuries/metabolism ; Spinal Cord Injuries/pathology ; Spinal Cord Injuries/physiopathology ; Time Factors ; rho GTP-Binding Proteins/metabolism ; rhoA GTP-Binding Protein

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Skocz do pozycji: 14.

Tytuł:: Tacrolimus downregulates inflammation by regulating pro‑/anti‑inflammatory responses in LPS‑induced keratitis.
Autorzy:: Yu Y; Department of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zhong J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Peng L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Wang B; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Li S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Huang H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Deng Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Zhang H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Yang R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.
Wang C; Department of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Yuan J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510064, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 5855-5862. Date of Electronic Publication: 2017 Aug 24.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*administration & dosage
Inflammation/*drug therapy
Keratitis/*drug therapy
Tacrolimus/*administration & dosage
Adult ; Cytokines/blood ; Female ; Gene Expression Regulation/drug effects ; Humans ; Immunity, Innate/drug effects ; Immunity, Innate/genetics ; Inflammation/blood ; Inflammation/chemically induced ; Inflammation/pathology ; Keratitis/blood ; Keratitis/chemically induced ; Keratitis/pathology ; Lipopolysaccharides/toxicity ; Male ; Middle Aged ; Monocytes/metabolism ; Monocytes/pathology ; Neutrophils/metabolism ; Neutrophils/pathology

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Skocz do pozycji: 15.

Tytuł:: The Acute Inflammatory Response to Absorbed Collagen Sponge Is Not Enhanced by BMP-2.
Autorzy:: Huang H; Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081LA Amsterdam, The Netherlands. .
Wismeijer D; Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081LA Amsterdam, The Netherlands. .
Hunziker EB; Departments of Osteoporosis and Orthopaedic Surgery, Inselspital (DKF), University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland. .
Wu G; Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081LA Amsterdam, The Netherlands. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2017 Feb 25; Vol. 18 (3). Date of Electronic Publication: 2017 Feb 25.
Typ publikacji:: Journal Article
MeSH Terms:: Absorbable Implants/*adverse effects
Bone Morphogenetic Protein 2/*metabolism
Collagen/*metabolism
Inflammation/*etiology
Inflammation/*metabolism
Animals ; Bone Regeneration ; Inflammation/pathology ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Neovascularization, Physiologic ; Osteogenesis ; Rats ; Recombinant Proteins

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Skocz do pozycji: 16.

Tytuł:: Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7.
Autorzy:: Wei G; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Jie Y; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Haibo L; Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai, China.
Chaoneng W; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Dong H; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Jianbing Z; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Junjie G; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Leilei M; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Hongtao S; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Yunzeng Z; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Junbo G; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2017 Feb 22; Vol. 7, pp. 42996. Date of Electronic Publication: 2017 Feb 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Exosomes/*metabolism
Inflammation/*etiology
Receptors, CCR7/*metabolism
Spleen/*metabolism
Animals ; Bone Marrow Cells/cytology ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cytokines/metabolism ; Dendritic Cells/cytology ; Dendritic Cells/metabolism ; Endocytosis ; Exosomes/transplantation ; Mice ; Mice, Inbred C57BL ; Microscopy, Fluorescence ; Optical Imaging ; Organic Chemicals/chemistry ; RNA Interference ; RNA, Small Interfering/metabolism ; Receptors, CCR7/antagonists & inhibitors ; Receptors, CCR7/genetics

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Skocz do pozycji: 17.

Tytuł:: Serum metabolomic signatures discriminate early liver inflammation and fibrosis stages in patients with chronic hepatitis B.
Autorzy:: Huang H; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, People's Republic of China.; Department of Infectious Diseases, Zhejiang Provincial People's Hospital, 310014 Hangzhou, People's Republic of China.
Sun Z; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, People's Republic of China.
Pan H; Department of Infectious Diseases, Zhejiang Provincial People's Hospital, 310014 Hangzhou, People's Republic of China.
Chen M; Department of Infectious Diseases, Zhejiang Provincial People's Hospital, 310014 Hangzhou, People's Republic of China.
Tong Y; Department of Infectious Diseases, Zhejiang Provincial People's Hospital, 310014 Hangzhou, People's Republic of China.
Zhang J; Department of Infectious Diseases, Zhejiang Provincial People's Hospital, 310014 Hangzhou, People's Republic of China.
Chen D; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, People's Republic of China.
Su X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, People's Republic of China.
Li L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, People's Republic of China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Aug 08; Vol. 6, pp. 30853. Date of Electronic Publication: 2016 Aug 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Metabolome*
Biomarkers/*blood
Hepatitis B, Chronic/*pathology
Inflammation/*pathology
Liver Cirrhosis/*pathology
Adult ; Cohort Studies ; Female ; Hepatitis B, Chronic/blood ; Humans ; Liver/pathology ; Lysophosphatidylcholines/blood ; Male ; Middle Aged ; Phosphatidylcholines/blood ; Phosphatidylinositols/blood ; Phosphatidylserines/blood ; Severity of Illness Index

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Skocz do pozycji: 18.

Tytuł:: Inhibition of Acute Lung Injury by TNFR-Fc through Regulation of an Inflammation-Oxidative Stress Pathway.
Autorzy:: Weifeng Y; Department of Respiratory Medicine, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China.
Li L; Department of Respiratory Medicine, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China.
Yujie H; Department of Respiratory Medicine, Hospital No 458 of PLA, Guangzhou, Guangdong, China.
Weifeng L; Department of Respiratory Medicine, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China.
Zhenhui G; MICU, Key Laboratory of Geriatric Infection and Organ Function Support of Guangdong Provincial, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China.
Wenjie H; Department of Respiratory Medicine, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Mar 18; Vol. 11 (3), pp. e0151672. Date of Electronic Publication: 2016 Mar 18 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acute Lung Injury/*pathology
Etanercept/*pharmacology
Inflammation/*immunology
Oxidative Stress/*physiology
Transcription Factor RelA/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Albumins/metabolism ; Animals ; Blood-Air Barrier/pathology ; Electrophoretic Mobility Shift Assay ; I-kappa B Kinase/metabolism ; Lipopolysaccharides/pharmacology ; Lung/pathology ; Malondialdehyde/metabolism ; Mice ; Mice, Inbred BALB C ; Phosphorylation ; Pulmonary Edema/pathology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/genetics

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Skocz do pozycji: 19.

Tytuł:: G-CSF Administration after the Intraosseous Infusion of Hypertonic Hydroxyethyl Starches Accelerating Wound Healing Combined with Hemorrhagic Shock.
Autorzy:: Huang H; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China; Medical College of Nankai University, Tianjin 300071, China.
Liu J; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Hao H; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Tong C; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Ti D; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Liu H; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Song H; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Jiang C; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Fu X; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China; Burns Institute, First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100853, China.
Han W; Institute of Basic Medicine, Chinese PLA General Hospital, Beijing 100853, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2016; Vol. 2016, pp. 5317630. Date of Electronic Publication: 2016 Feb 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Granulocyte Colony-Stimulating Factor/*administration & dosage
Inflammation/*drug therapy
Shock, Hemorrhagic/*drug therapy
Wound Healing/*drug effects
Animals ; Humans ; Hydroxyethyl Starch Derivatives/administration & dosage ; Inflammation/pathology ; Infusions, Intraosseous ; Rats ; Resuscitation ; Shock, Hemorrhagic/pathology ; Skin/drug effects ; Skin/injuries ; Skin/pathology

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Skocz do pozycji: 20.

Tytuł:: Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Autorzy:: Shi J; Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, School of Life Sciences, Tsinghua University, 100084, China.; National Institute of Biological Sciences, Beijing 102206, China.
Zhao Y; National Institute of Biological Sciences, Beijing 102206, China.
Wang K; National Institute of Biological Sciences, Beijing 102206, China.
Shi X; National Institute of Biological Sciences, Beijing 102206, China.
Wang Y; National Institute of Biological Sciences, Beijing 102206, China.
Huang H; National Institute of Biological Sciences, Beijing 102206, China.
Zhuang Y; National Institute of Biological Sciences, Beijing 102206, China.
Cai T; National Institute of Biological Sciences, Beijing 102206, China.
Wang F; National Institute of Biological Sciences, Beijing 102206, China.
Shao F; National Institute of Biological Sciences, Beijing 102206, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; National Institute of Biological Sciences, Beijing, Collaborative Innovation Center for Cancer Medicine, Beijing 102206, China.; Pokaż więcej
Źródło:: Nature [Nature] 2015 Oct 29; Vol. 526 (7575), pp. 660-5. Date of Electronic Publication: 2015 Sep 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Processing, Post-Translational*
Apoptosis/*drug effects
Apoptosis Regulatory Proteins/*metabolism
Caspases/*metabolism
Inflammation/*enzymology
Neoplasm Proteins/*metabolism
Animals ; Apoptosis Regulatory Proteins/antagonists & inhibitors ; Apoptosis Regulatory Proteins/chemistry ; Apoptosis Regulatory Proteins/deficiency ; CRISPR-Cas Systems ; Caspase 1/metabolism ; Cell Line ; Humans ; Inflammasomes/metabolism ; Interleukin-1beta/metabolism ; Intracellular Signaling Peptides and Proteins ; Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Necrosis ; Neoplasm Proteins/chemistry ; Phosphate-Binding Proteins ; Protein Structure, Tertiary ; Proteins/chemistry ; Proteins/genetics ; Proteins/metabolism ; Substrate Specificity

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