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Tytuł:
Initiation and Execution of Programmed Cell Death and Regulation of Reactive Oxygen Species in Plants.
Autorzy:
Ye C; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Zheng S; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Jiang D; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Lu J; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Huang Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Liu Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Zhou H; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Zhuang C; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Li J; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.; Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions, South China Agricultural University, Guangzhou 510642, China.; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 30; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis/*physiology
Plants/*metabolism
Reactive Oxygen Species/*metabolism
Autophagy/physiology ; Chloroplasts/metabolism ; Mitochondria/metabolism ; Models, Biological ; Oxidation-Reduction ; Plant Cells/physiology ; Signal Transduction
Czasopismo naukowe
Tytuł:
CircRNA_0092516 regulates chondrocyte proliferation and apoptosis in osteoarthritis through the miR-337-3p/PTEN axis.
Autorzy:
Huang Z; Department of Orthopedics, The Third Affiliated Hospital of Suchow University, No. 185 Juqian Road, Changzhou 213000, Jiangsu Province, China.
Ma W; Department of Orthopedics, The Third Affiliated Hospital of Suchow University, No. 185 Juqian Road, Changzhou 213000, Jiangsu Province, China.
Xiao J; Department of Orthopedics, The Third Affiliated Hospital of Suchow University, No. 185 Juqian Road, Changzhou 213000, Jiangsu Province, China.
Dai X; Department of Orthopedics, The Third Affiliated Hospital of Suchow University, No. 185 Juqian Road, Changzhou 213000, Jiangsu Province, China.
Ling W; Department of Orthopedics, The Third Affiliated Hospital of Suchow University, No. 185 Juqian Road, Changzhou 213000, Jiangsu Province, China.
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Źródło:
Journal of biochemistry [J Biochem] 2021 Apr 29; Vol. 169 (4), pp. 467-475.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Cell Proliferation*
Signal Transduction*
Chondrocytes/*metabolism
MicroRNAs/*metabolism
PTEN Phosphohydrolase/*metabolism
RNA, Circular/*metabolism
Aged ; Cell Line ; Chondrocytes/pathology ; Female ; Humans ; Male ; MicroRNAs/genetics ; Middle Aged ; PTEN Phosphohydrolase/genetics ; RNA, Circular/genetics
Czasopismo naukowe
Tytuł:
Overexpression of antisense long non‑coding RNA ZNF710‑AS1‑202 promotes cell proliferation and inhibits apoptosis of clear cell renal cell carcinoma via regulation of ZNF710 expression.
Autorzy:
Li G; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Xie M; First Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Huang Z; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Li H; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Li P; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Zhang Z; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Ding Y; Department of Otology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Jia Z; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Yang J; Second Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2020 Jun; Vol. 21 (6), pp. 2502-2512. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Carcinoma, Renal Cell/*genetics
Carcinoma, Renal Cell/*metabolism
Cell Proliferation/*drug effects
Kidney Neoplasms/*genetics
Kidney Neoplasms/*metabolism
RNA, Long Noncoding/*pharmacology
Adult ; Aged ; Cell Line, Tumor ; Disease Progression ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; RNA, Long Noncoding/genetics ; RNA, Messenger ; RNA, Small Interfering/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł:
Iridoid glycosides from Radix Scrophulariae attenuates focal cerebral ischemia‑reperfusion injury via inhibiting endoplasmic reticulum stress‑mediated neuronal apoptosis in rats.
Autorzy:
Chen Y; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Zhang L; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Gong X; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Gong H; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Cheng R; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Qiu F; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Zhong X; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
Huang Z; Institute of Traditional Chinese Medicine Resources, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 311400, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2020 Jan; Vol. 21 (1), pp. 131-140. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Brain Infarction/*drug therapy
Endoplasmic Reticulum Stress/*drug effects
Iridoid Glycosides/*pharmacology
Neurons/*metabolism
Ranunculaceae/*chemistry
Reperfusion Injury/*drug therapy
Animals ; Brain Infarction/metabolism ; Brain Infarction/pathology ; Disease Models, Animal ; Iridoid Glycosides/chemistry ; Male ; Neurons/pathology ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł:
Amelioration of Enterotoxigenic Escherichia coli -Induced Intestinal Barrier Disruption by Low-Molecular-Weight Chitosan in Weaned Pigs is Related to Suppressed Intestinal Inflammation and Apoptosis.
Autorzy:
Wan J; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Zhang J; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Wu G; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Chen D; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Yu B; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Huang Z; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Luo Y; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Zheng P; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Luo J; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Mao X; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Yu J; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
He J; Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jul 16; Vol. 20 (14). Date of Electronic Publication: 2019 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Anti-Inflammatory Agents/*therapeutic use
Chitosan/*therapeutic use
Escherichia coli Infections/*drug therapy
Intestinal Mucosa/*drug effects
Animals ; Anti-Inflammatory Agents/pharmacology ; Chitosan/pharmacology ; Enterotoxigenic Escherichia coli ; Interleukin-6/genetics ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Occludin/genetics ; Occludin/metabolism ; Swine ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Transcription Factor RelA/genetics ; Transcription Factor RelA/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
A study of natural IgG antibodies against ATP-binding cassette subfamily C member 3 in oral squamous cell carcinoma.
Autorzy:
Liu X; Beijing Institution of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, People's Republic of China.
Huang Z; Department of Radiology, Jilin Cancer Hospital, Changchun, People's Republic of China.
He Z; Department of Transfusion Research, Dongguan Blood Center, Dongguan, People's Republic of China.
Meng Q; Institute of Laboratory Medicine, Guangdong Medical University, Dongguan, People's Republic of China.
Wang X; Beijing Institution of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Hu Y; Beijing Institution of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2019; Vol. 15 (4), pp. 921-926.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Autoantibodies/*blood
Biomarkers, Tumor/*blood
Carcinoma, Squamous Cell/*immunology
Cell Proliferation/*drug effects
Mouth Neoplasms/*immunology
Multidrug Resistance-Associated Proteins/*immunology
Autoantibodies/administration & dosage ; Autoantibodies/immunology ; Biomarkers, Tumor/immunology ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/pathology ; Cell Cycle/drug effects ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Mouth Neoplasms/blood ; Mouth Neoplasms/pathology ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
MicroRNA-126 attenuates cell apoptosis by targeting TRAF7 in acute myeloid leukemia cells.
Autorzy:
Ding Q; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.
Wang Q; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.
Ren Y; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.
Zhu HQ; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.
Huang Z; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.; Department of Hematology, Gui Zhou Provincial People's Hospital, Guiyang 550002, P.R. China.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2018 Dec; Vol. 96 (6), pp. 840-846.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*genetics
Leukemia, Myeloid, Acute/*genetics
MicroRNAs/*genetics
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/*genetics
Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation/genetics ; Down-Regulation ; Humans ; Up-Regulation
Czasopismo naukowe
Tytuł:
Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis.
Autorzy:
Han D; Department of Ophthalmology, Jinling Hospital, Nanjing, 210002, China.
Wu X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China.
Liu L; The Third People's Hospital of Jingdezhen, Jingdezhen, 333000, China.
Shu W; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China.
Huang Z; Department of Ophthalmology, Jinling Hospital, Nanjing, 210002, China. .
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Źródło:
Scientific reports [Sci Rep] 2018 Oct 11; Vol. 8 (1), pp. 15137. Date of Electronic Publication: 2018 Oct 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Autophagy/*drug effects
Oxidative Stress/*drug effects
Phenanthrenes/*pharmacology
Protective Agents/*pharmacology
Biomarkers ; Cell Line ; Dose-Response Relationship, Drug ; Humans ; Hydrogen Peroxide/metabolism ; Hydrogen Peroxide/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells.
Autorzy:
Liu L; Department of Pharmacy, Henan University of Science and Technology, 263 Kaiyuan Avenue, Luoyang, 471023, China. .
Huang Z; Department of Pharmacy, Henan University of Science and Technology, 263 Kaiyuan Avenue, Luoyang, 471023, China.
Chen J; Department of Pharmacy, Henan University of Science and Technology, 263 Kaiyuan Avenue, Luoyang, 471023, China.
Wang J; Department of Pharmacy, Henan University of Science and Technology, 263 Kaiyuan Avenue, Luoyang, 471023, China.
Wang S; Department of Pharmacy, Henan University of Science and Technology, 263 Kaiyuan Avenue, Luoyang, 471023, China.
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2018 Jul 09; Vol. 37 (1), pp. 142. Date of Electronic Publication: 2018 Jul 09.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Azo Compounds/*pharmacology
Carcinoma, Hepatocellular/*metabolism
Caspases/*metabolism
Liver Neoplasms/*metabolism
Piperazines/*pharmacology
Protein Phosphatase 2/*metabolism
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Male ; Membrane Potential, Mitochondrial/drug effects ; Nitric Oxide/metabolism ; Rats
Czasopismo naukowe
Tytuł:
18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
Autorzy:
Chen J; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Zhang ZQ; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Song J; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Liu QM; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Wang C; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Huang Z; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Chu L; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China.
Liang HF; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China. .
Zhang BX; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China. .
Chen XP; Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China. .
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Źródło:
Scientific reports [Sci Rep] 2018 Jun 19; Vol. 8 (1), pp. 9365. Date of Electronic Publication: 2018 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Autophagy/*drug effects
Carcinoma, Hepatocellular/*metabolism
Glycyrrhetinic Acid/*analogs & derivatives
Liver Neoplasms/*metabolism
Unfolded Protein Response/*genetics
Apoptosis/genetics ; Autophagy/genetics ; Carcinoma, Hepatocellular/genetics ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; G1 Phase/drug effects ; G1 Phase/genetics ; Glycyrrhetinic Acid/pharmacology ; Hep G2 Cells ; Humans ; Liver Neoplasms/genetics ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Resting Phase, Cell Cycle/drug effects ; Resting Phase, Cell Cycle/genetics ; Unfolded Protein Response/drug effects ; X-Box Binding Protein 1/genetics ; X-Box Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł:
Induction of apoptosis in imatinib sensitive and resistant chronic myeloid leukemia cells by efficient disruption of bcr-abl oncogene with zinc finger nucleases.
Autorzy:
Huang N; Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, No.1, Yixueyuan Road, Chongqing, 400016, People's Republic of China.
Huang Z; Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, No.1, Yixueyuan Road, Chongqing, 400016, People's Republic of China.
Gao M; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Luo Z; Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, No.1, Yixueyuan Road, Chongqing, 400016, People's Republic of China.
Zhou F; Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, No.1, Yixueyuan Road, Chongqing, 400016, People's Republic of China.
Liu L; Department of Hematology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xiao Q; Department of Hematology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Wang X; Department of Hematology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Feng W; Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, No.1, Yixueyuan Road, Chongqing, 400016, People's Republic of China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2018 Mar 20; Vol. 37 (1), pp. 62. Date of Electronic Publication: 2018 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Apoptosis/*genetics
Drug Resistance, Neoplasm/*genetics
Fusion Proteins, bcr-abl/*genetics
Fusion Proteins, bcr-abl/*metabolism
Imatinib Mesylate/*pharmacology
Zinc Finger Nucleases/*metabolism
Animals ; Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Disease Models, Animal ; Female ; Fusion Proteins, bcr-abl/chemistry ; Gene Editing ; Genetic Vectors ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Mice ; Neoplastic Stem Cells ; Recombinational DNA Repair ; Sequence Analysis, DNA ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
TAK1 mediates apoptosis via p38 involve in ischemia-induced renal fibrosis.
Autorzy:
Zhou J; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Zhong J; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Huang Z; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Liao M; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Lin S; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Chen J; a Department of Anesthesiology , The First People's Hospital of Foshan , Foshan , Guangdong Province , China.
Chen H; b Department of Anesthesiology , The Eighth People's Hospital of Guangzhou , Guangzhou , Guangdong Province , China.
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Źródło:
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2018; Vol. 46 (sup1), pp. 1016-1025. Date of Electronic Publication: 2018 Apr 16.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
MAP Kinase Signaling System*
Ischemia/*metabolism
Ischemia/*pathology
Kidney/*pathology
MAP Kinase Kinase Kinases/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Collagen Type I/metabolism ; Epithelial Cells/pathology ; Fibronectins/metabolism ; Fibrosis ; Kidney Tubules/pathology ; Mice ; Phosphorylation ; Up-Regulation
Czasopismo naukowe
Tytuł:
Adipose‑derived mesenchymal stem cells attenuate cisplatin‑induced apoptosis in epithelial ovarian cancer cells.
Autorzy:
Wen Y; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Guo Y; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Huang Z; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Cai J; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Wang Z; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Dec; Vol. 16 (6), pp. 9587-9592. Date of Electronic Publication: 2017 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Communication*
Adipose Tissue/*cytology
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cisplatin/*pharmacology
Mesenchymal Stem Cells/*metabolism
Neoplasms, Glandular and Epithelial/*metabolism
Ovarian Neoplasms/*metabolism
Carcinoma, Ovarian Epithelial ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Coculture Techniques ; Dose-Response Relationship, Drug ; Humans ; Mesenchymal Stem Cells/cytology
Czasopismo naukowe
Tytuł:
PTEN Reduced UVB-Mediated Apoptosis in Retinal Pigment Epithelium Cells.
Autorzy:
He J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Long C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Huang Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Zhou X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Kuang X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China; Biobank of Eye, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Liu L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Liu H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Tang Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Fan Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Ning J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Ma X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Zhang Q; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
Shen H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China; Biobank of Eye, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 Xianlie Road, Guangzhou 510060, China.
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Źródło:
BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 3681707. Date of Electronic Publication: 2017 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*radiation effects
Macular Degeneration/*enzymology
Oxidative Stress/*radiation effects
PTEN Phosphohydrolase/*biosynthesis
Retinal Pigment Epithelium/*enzymology
Ultraviolet Rays/*adverse effects
Apoptosis/drug effects ; Benzothiazoles/pharmacology ; Cell Line ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Down-Regulation/drug effects ; Down-Regulation/radiation effects ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/radiation effects ; Humans ; Macular Degeneration/pathology ; Oxidative Stress/drug effects ; Retinal Pigment Epithelium/pathology ; Toluene/analogs & derivatives ; Toluene/pharmacology ; Tumor Suppressor Protein p53/antagonists & inhibitors ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Dihydrotanshinone induces apoptosis of SGC7901 and MGC803 cells via activation of JNK and p38 signalling pathways.
Autorzy:
Cheng R; a College of Pharmaceutical Science , Zhejiang Chinese Medical University , Hangzhou , P.R. China.
Chen J; a College of Pharmaceutical Science , Zhejiang Chinese Medical University , Hangzhou , P.R. China.
Wang Y; a College of Pharmaceutical Science , Zhejiang Chinese Medical University , Hangzhou , P.R. China.
Ge Y; b The First Affiliated Hospital, Zhejiang Chinese Medical University , Hangzhou , P.R. China.
Huang Z; a College of Pharmaceutical Science , Zhejiang Chinese Medical University , Hangzhou , P.R. China.
Zhang G; c College of Basic Medical Science , Zhejiang Chinese Medical University , Hangzhou , P.R. China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2016 Dec; Vol. 54 (12), pp. 3019-3025. Date of Electronic Publication: 2016 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Abietanes/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
MAP Kinase Signaling System/*drug effects
Apoptosis/physiology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; Enzyme Activation/physiology ; Humans ; MAP Kinase Signaling System/physiology
Czasopismo naukowe
Tytuł:
Vitamin D and its receptor regulate lipopolysaccharide-induced transforming growth factor-β, angiotensinogen expression and podocytes apoptosis through the nuclear factor-κB pathway.
Autorzy:
Xu L; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhang P; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Guan H; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huang Z; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
He X; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wan X; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiao H; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li Y; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
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Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2016 Sep; Vol. 7 (5), pp. 680-8. Date of Electronic Publication: 2016 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Angiotensinogen/*metabolism
Inflammation/*metabolism
NF-kappa B/*metabolism
Podocytes/*metabolism
Receptors, Calcitriol/*metabolism
Transforming Growth Factor beta/*metabolism
Vitamin D/*metabolism
Animals ; Cells, Cultured ; Inflammation/chemically induced ; Lipopolysaccharides ; Mice ; Podocytes/drug effects ; Signal Transduction/drug effects ; Vitamin D/pharmacology
Czasopismo naukowe
Tytuł:
Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.
Autorzy:
Yu M; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Lu G; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Zhu X; Department of Microbiology, Zhongshan School of Medicine, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Huang Z; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Feng C; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Fang R; Key Laboratory of Assisted Circulation, Ministry of Health, Guangzhou, Guangdong 710068, P.R. China.
Wang Y; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Gao X; Department of Cardiology, First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 Apr; Vol. 13 (4), pp. 3265-72. Date of Electronic Publication: 2016 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Down-Regulation/*drug effects
Glucose/*pharmacology
Tumor Necrosis Factor Ligand Superfamily Member 15/*metabolism
Up-Regulation/*drug effects
Vascular Endothelial Growth Factor A/*metabolism
Blotting, Western ; Human Umbilical Vein Endothelial Cells ; Humans ; Nitric Oxide Synthase Type III/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA Interference ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Real-Time Polymerase Chain Reaction ; Signal Transduction/drug effects ; Transfection ; Tumor Necrosis Factor Ligand Superfamily Member 15/antagonists & inhibitors ; Tumor Necrosis Factor Ligand Superfamily Member 15/genetics ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł:
Effects of UCP4 on the Proliferation and Apoptosis of Chondrocytes: Its Possible Involvement and Regulation in Osteoarthritis.
Autorzy:
Huang Z; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, Hangzhou, China.; Department of Orthopaedic Surgery, Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.
Li J; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, Hangzhou, China.; Department of Orthopaedic Surgery, Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Du S; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Chen G; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Qi Y; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Huang L; Zhejiang Chinese Medical University, Hangzhou, China.
Xiao L; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Tong P; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Źródło:
PloS one [PLoS One] 2016 Mar 02; Vol. 11 (3), pp. e0150684. Date of Electronic Publication: 2016 Mar 02 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Down-Regulation*
Chondrocytes/*pathology
Ion Channels/*genetics
Membrane Transport Proteins/*genetics
Mitochondrial Proteins/*genetics
Osteoarthritis/*genetics
Adult ; Aged ; Animals ; Cartilage, Articular/metabolism ; Cartilage, Articular/pathology ; Cell Proliferation ; Cells, Cultured ; Chondrocytes/metabolism ; Humans ; Ion Channels/metabolism ; Leptin/metabolism ; Male ; Membrane Potential, Mitochondrial ; Membrane Transport Proteins/metabolism ; Middle Aged ; Mitochondrial Proteins/metabolism ; Mitochondrial Uncoupling Proteins ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; RNA Interference ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
EBP50 induces apoptosis in macrophages by upregulating nitric oxide production to eliminate intracellular Mycobacterium tuberculosis.
Autorzy:
Guo Y; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Deng Y; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Huang Z; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Luo Q; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Peng Y; Department of Tuberculosis, Jiangxi Chest Hospital, Nanchang, 330006, China.
Chen J; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Jiang H; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Ye J; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Li J; Department of Clinical Laboratory, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
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Źródło:
Scientific reports [Sci Rep] 2016 Jan 05; Vol. 6, pp. 18961. Date of Electronic Publication: 2016 Jan 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/genetics
Apoptosis*/immunology
Macrophages/*microbiology
Macrophages/*physiology
Mycobacterium tuberculosis/*immunology
Nitric Oxide/*biosynthesis
Phosphoproteins/*metabolism
Sodium-Hydrogen Exchangers/*metabolism
Animals ; Caspase 3/metabolism ; Cell Line ; Cytotoxicity, Immunologic ; Flow Cytometry ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Mice ; Nitric Oxide Synthase Type II/metabolism ; Phagocytosis/immunology ; Phagosomes/metabolism ; Phosphoproteins/genetics ; Sodium-Hydrogen Exchangers/genetics ; Tuberculosis/genetics ; Tuberculosis/immunology ; Tuberculosis/metabolism ; Tuberculosis/microbiology ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells.
Autorzy:
Ding Q; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Chen Y; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Zhang Q; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Guo Y; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Huang Z; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Dai L; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
Cao S; Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410208, P.R.China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2015 Oct; Vol. 12 (4), pp. 5100-8. Date of Electronic Publication: 2015 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Epithelial Cells/*drug effects
Flavonoids/*pharmacology
Forkhead Transcription Factors/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Apoptosis Regulatory Proteins/agonists ; Apoptosis Regulatory Proteins/antagonists & inhibitors ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; Cell Line, Tumor ; Cisplatin/pharmacology ; Drug Resistance, Neoplasm/genetics ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Forkhead Box Protein O3 ; Forkhead Transcription Factors/agonists ; Forkhead Transcription Factors/metabolism ; Gene Silencing ; Humans ; Membrane Proteins/agonists ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Ovary/drug effects ; Ovary/metabolism ; Ovary/pathology ; Proto-Oncogene Proteins/agonists ; Proto-Oncogene Proteins/antagonists & inhibitors ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt/agonists ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction
Czasopismo naukowe

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