Cellular targets and lysine selectivity of the HERC5 ISG15 ligase.
Autorzy:
Zhao X; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Perez JM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Faull PA; Biological Mass Spectrometry Facility, Center for Biomedical Research Support, University of Texas at Austin, Austin, TX 78712, USA. Chan C; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Munting FW; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Canadeo LA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Cenik C; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.; John Ring LaMontagne Center for Infectious Disease, University of Texas at Austin, Austin, TX 78712, USA.
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Źródło:
IScience [iScience] 2024 Jan 09; Vol. 27 (2), pp. 108820. Date of Electronic Publication: 2024 Jan 09 (Print Publication: 2024).
6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro.
Autorzy:
Swaim CD; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA. Dwivedi V; Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, USA. Perng YC; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. Zhao X; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA. Canadeo LA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA. Harastani HH; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. Darling TL; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. Boon ACM; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. Lenschow DJ; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. Kulkarni V; Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, USA.
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Źródło:
IScience [iScience] 2021 Oct 22; Vol. 24 (10), pp. 103213. Date of Electronic Publication: 2021 Oct 02.
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.
Autorzy:
Ryu SW; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Stewart R; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Pectol DC; The Department of Chemistry, Texas A&M University, College Station, Texas, United States of America. Ender NA; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Wimalarathne O; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Lee JH; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Zanini CP; Department of Statistics & Data Sciences, University of Texas at Austin, Austin, Texas, United States of America. Harvey A; Thermo Fisher Scientific, Austin, Texas, United States of America. HuibregtseJM; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America. Mueller P; Department of Statistics & Data Sciences, University of Texas at Austin, Austin, Texas, United States of America. Paull TT; The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2020 Jul 20; Vol. 18 (7), pp. e3000606. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins.
Autorzy:
Swaim CD; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Canadeo LA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Monte KJ; Departments of Internal Medicine and Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Khanna S; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Lenschow DJ; Departments of Internal Medicine and Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: huibregtse@austin.utexas.edu.
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Źródło:
Cell reports [Cell Rep] 2020 Jun 16; Vol. 31 (11), pp. 107772.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
A masked initiation region in retinoblastoma protein regulates its proteasomal degradation.
Autorzy:
Tomita T; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA. HuibregtseJM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA. Matouschek A; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA. .
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Źródło:
Nature communications [Nat Commun] 2020 Apr 24; Vol. 11 (1), pp. 2019. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor.
Autorzy:
Swaim CD; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Scott AF; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Canadeo LA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: huibregtse@austin.utexas.edu.
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Źródło:
Molecular cell [Mol Cell] 2017 Nov 02; Vol. 68 (3), pp. 581-590.e5.
Enzyme-substrate relationships in the ubiquitin system: approaches for identifying substrates of ubiquitin ligases.
Autorzy:
O'Connor HF; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA. huibregtse@austin.utexas.edu.
A Billion Ubiquitin Variants to Probe and Modulate the UPS.
Autorzy:
Canadeo LA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. HuibregtseJM; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: huibregtse@austin.utexas.edu.
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