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Wyszukujesz frazę ""Human T-lymphotropic virus 1"" wg kryterium: Temat


Tytuł :
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ.
Autorzy :
Barski MS; Imperial College London, St Mary's Hospital, Department of Infectious Disease, Section of Virology, Norfolk Place, London, W2 1PG, UK.
Minnell JJ; Imperial College London, St Mary's Hospital, Department of Infectious Disease, Section of Virology, Norfolk Place, London, W2 1PG, UK.
Hodakova Z; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Pye VE; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Nans A; Structural Biology Science Technology Platform, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Cherepanov P; Imperial College London, St Mary's Hospital, Department of Infectious Disease, Section of Virology, Norfolk Place, London, W2 1PG, UK.; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Maertens GN; Imperial College London, St Mary's Hospital, Department of Infectious Disease, Section of Virology, Norfolk Place, London, W2 1PG, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 07; Vol. 11 (1), pp. 5043. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Integration*
Human T-lymphotropic virus 1/*pathogenicity
Integrases/*ultrastructure
Protein Phosphatase 2/*ultrastructure
Simian T-lymphotropic virus 1/*enzymology
Viral Proteins/*ultrastructure
Amino Acid Motifs/genetics ; Cloning, Molecular ; Cryoelectron Microscopy ; Crystallography, X-Ray ; DNA, Viral/metabolism ; DNA, Viral/ultrastructure ; Human T-lymphotropic virus 1/enzymology ; Human T-lymphotropic virus 1/genetics ; Humans ; Integrases/genetics ; Integrases/metabolism ; Leukemia-Lymphoma, Adult T-Cell/pathology ; Leukemia-Lymphoma, Adult T-Cell/virology ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Paraparesis, Tropical Spastic/pathology ; Paraparesis, Tropical Spastic/virology ; Protein Multimerization ; Protein Phosphatase 2/genetics ; Protein Phosphatase 2/metabolism ; Protein Structure, Quaternary ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Recombinant Proteins/ultrastructure ; Sequence Homology, Amino Acid ; Simian T-lymphotropic virus 1/genetics ; Single Molecule Imaging ; Viral Proteins/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8.
Autorzy :
Donhauser N; Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Socher E; Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Millen S; Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Heym S; Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Sticht H; Division of Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Thoma-Kress AK; Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 30; Vol. 16 (9), pp. e1008879. Date of Electronic Publication: 2020 Sep 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Adhesion Molecules*/chemistry
Cell Adhesion Molecules*/genetics
Cell Adhesion Molecules*/metabolism
Focal Adhesions*/chemistry
Focal Adhesions*/genetics
Focal Adhesions*/metabolism
Focal Adhesions*/virology
Gene Products, gag*/chemistry
Gene Products, gag*/genetics
Gene Products, gag*/metabolism
Human T-lymphotropic virus 1*/chemistry
Human T-lymphotropic virus 1*/genetics
Human T-lymphotropic virus 1*/metabolism
Microfilament Proteins*/chemistry
Microfilament Proteins*/genetics
Microfilament Proteins*/metabolism
Phosphoproteins*/chemistry
Phosphoproteins*/genetics
Phosphoproteins*/metabolism
T-Lymphocytes*/chemistry
T-Lymphocytes*/metabolism
T-Lymphocytes*/virology
Humans ; Jurkat Cells ; Protein Domains
Czasopismo naukowe
Tytuł :
The relative contributions of infectious and mitotic spread to HTLV-1 persistence.
Autorzy :
Laydon DJ; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom.; Section of Immunology, Wright-Fleming Institute, Imperial College School of Medicine, London, United Kingdom.
Sunkara V; Department of Mathematics and Computer Science, Freie Universität, Arnimallee, Berlin, Germany.
Boelen L; Section of Immunology, Wright-Fleming Institute, Imperial College School of Medicine, London, United Kingdom.
Bangham CRM; Section of Immunology, Wright-Fleming Institute, Imperial College School of Medicine, London, United Kingdom.
Asquith B; Section of Immunology, Wright-Fleming Institute, Imperial College School of Medicine, London, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Sep 17; Vol. 16 (9), pp. e1007470. Date of Electronic Publication: 2020 Sep 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HTLV-I Infections*/physiopathology
HTLV-I Infections*/virology
Host-Pathogen Interactions*/genetics
Host-Pathogen Interactions*/physiology
Human T-lymphotropic virus 1*/classification
Human T-lymphotropic virus 1*/genetics
Human T-lymphotropic virus 1*/pathogenicity
CD4-Positive T-Lymphocytes/virology ; Humans ; Mitosis/genetics ; Mitosis/physiology ; Models, Biological ; Proviruses/genetics ; Proviruses/pathogenicity ; Viral Load/genetics ; Virus Integration/genetics
Czasopismo naukowe
Tytuł :
Yin Yang 1 is a potent activator of human T lymphotropic virus type 1 LTR-driven gene expression via RNA binding.
Autorzy :
Wang GZ; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032.
Goff SP; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032; .; Department of Microbiology and Immunology, Columbia University, New York, NY 10032.; Howard Hughes Medical Institute, Columbia University, New York, NY 10032.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 04; Vol. 117 (31), pp. 18701-18710. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Human T-lymphotropic virus 1*/genetics
Human T-lymphotropic virus 1*/metabolism
YY1 Transcription Factor*/genetics
YY1 Transcription Factor*/metabolism
Gene Expression Regulation, Viral/*genetics
RNA/*metabolism
Terminal Repeat Sequences/*genetics
HEK293 Cells ; Humans ; Jurkat Cells ; Protein Binding/genetics ; RNA/genetics ; Transcriptional Activation/genetics
Czasopismo naukowe
Tytuł :
Impact of fractures and orthopedic surgeries in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis.
Autorzy :
Julca-Copello P; Universidad Peruana Cayetano Heredia, School of Medicine, Lima, Perú.
Schwalb A; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
Cachay R; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
Tipismana M; Universidad Peruana Cayetano Heredia, School of Medicine, Lima, Perú.; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.; Hospital Cayetano Heredia, Neurology Department, Lima, Perú.
Alvarez C; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
Mejía F; Universidad Peruana Cayetano Heredia, School of Medicine, Lima, Perú.; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
González-Lagos E; Universidad Peruana Cayetano Heredia, School of Medicine, Lima, Perú.; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
Gotuzzo E; Universidad Peruana Cayetano Heredia, School of Medicine, Lima, Perú.; Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Perú.
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Źródło :
Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2020 Sep 11; Vol. 53, pp. e20200101. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
HTLV-I Infections*
Human T-lymphotropic virus 1*
Orthopedic Procedures*
Paraparesis, Tropical Spastic*
Cohort Studies ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
HTLV-1 seropositive patients with lung cancer treated with PD-1 inhibitors.
Autorzy :
Yoneshima Y; Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kato K; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Minami H; Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan.
Ikeda M; Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan.
Watanabe H; Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan.
Yoshimoto G; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Miyamoto T; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Akashi K; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nakanishi Y; Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Okamoto I; Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Sep; Vol. 111 (9), pp. 3395-3396. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Antineoplastic Agents, Immunological/*adverse effects
Carrier State/*diagnosis
HTLV-I Infections/*diagnosis
Human T-lymphotropic virus 1/*immunology
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Aged ; Antibodies, Monoclonal, Humanized/adverse effects ; Asymptomatic Infections ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/immunology ; Carrier State/blood ; Carrier State/immunology ; Carrier State/virology ; Follow-Up Studies ; HTLV-I Antibodies/blood ; HTLV-I Antibodies/immunology ; HTLV-I Infections/chemically induced ; HTLV-I Infections/immunology ; HTLV-I Infections/virology ; Human T-lymphotropic virus 1/isolation & purification ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/immunology ; Male ; Middle Aged ; Nivolumab/adverse effects ; Programmed Cell Death 1 Receptor/immunology ; Retrospective Studies
Raport
Tytuł :
A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo.
Autorzy :
Saito M; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan. .
Hasegawa H; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan. .; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. .
Yamauchi S; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Nakagawa S; Biomedical Informatics Laboratory, Department of Molecular Life Science, Tokai University School of Medicine, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Kanagawa, Japan.
Sasaki D; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Nao N; Department of Virology III, National Institute of Infectious Diseases, Tokyo, Japan.
Tanio M; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.
Wada Y; Biotechnological Research Support Division, FASMAC Co., Ltd, Kanagawa, Japan.
Matsudaira T; Biotechnological Research Support Division, FASMAC Co., Ltd, Kanagawa, Japan.
Momose H; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.
Kuramitsu M; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, Japan.
Yamagishi M; Graduate School of Frontier Sciences, Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, Japan.
Nakashima M; Graduate School of Frontier Sciences, Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, Japan.
Nakahata S; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, University of Miyazaki, Miyazaki, Japan.
Iha H; Department of Microbiology, Faculty of Medicine, Oita University, Oita, Japan.
Ogata M; Department of Hematology, Oita University, Oita, Japan.
Imaizumi Y; Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan.
Uchimaru K; Graduate School of Frontier Sciences, Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, Japan.
Morishita K; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, University of Miyazaki, Miyazaki, Japan.
Watanabe T; The Institute of Medical Science Research Hospital and Future Center Initiative, The University of Tokyo, Tokyo, Japan.
Miyazaki Y; Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan.; Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.
Yanagihara K; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2020 Sep; Vol. 112 (3), pp. 300-306. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Clone Cells*
Human T-lymphotropic virus 1*/genetics
HTLV-I Infections/*diagnosis
Leukemia-Lymphoma, Adult T-Cell/*diagnosis
Leukemia-Lymphoma, Adult T-Cell/*virology
Nucleic Acid Amplification Techniques/*methods
High-Throughput Nucleotide Sequencing/methods ; Humans
Czasopismo naukowe
Tytuł :
HTLV-I induces lesions in the pulmonary system: A systematic review.
Autorzy :
Normando VMF PhD; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
Dias ÁRN Me; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
da Silva ALSE Lic; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
da Silva Pinto D PhD; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil. Electronic address: .
de Souza Santos MC PhD; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
Rodrigues CL Lic; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
de Oliveira EM PhD; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
de Souza Filho LEC Me; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
de Brito Vieira W Esp; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil; Santa Casa de Misericórdia Foundation, Belém, PA, Brazil. Electronic address: .
Andriolo RB PhD; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
Sousa RCM PhD; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil. Electronic address: .
Falcão LFM PhD; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil. Electronic address: .
Quaresma JAS PhD; Center for Tropical Medicine, Federal University of Pará, Belém, PA, Brazil; Center for Biological and Health Sciences, State University of Pará, Belém, PA, Brazil; Evandro Chagas Institute, Ministry of Health, Ananindeua, Belém, PA, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 01; Vol. 256, pp. 117979. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Human T-lymphotropic virus 1*/isolation & purification
HTLV-I Infections/*diagnostic imaging
Lung Diseases/*diagnostic imaging
Animals ; Case-Control Studies ; Cohort Studies ; HTLV-I Infections/physiopathology ; Humans ; Lung Diseases/physiopathology ; Respiratory Tract Infections/diagnostic imaging ; Respiratory Tract Infections/physiopathology
Czasopismo naukowe
Tytuł :
Use of synthetic oligonucleotides for determination of HTLV-1 proviral load by real-time PCR: a helpful alternative approach in the clinical management.
Autorzy :
Bandeira LM; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Puga MAM; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
de Paula VS; Oswaldo Cruz Institute, Rio de Janeiro, RJ, Brazil.
Demarchi LHF; Central Public Health Laboratory, Lacen/MS, Campo Grande, MS, Brazil.
Lichs GGC; Central Public Health Laboratory, Lacen/MS, Campo Grande, MS, Brazil.
Domingos JA; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
da Cunha RV; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.; Oswaldo Cruz Foundation, Campo Grande, MS, Brazil.
Uehara SNO; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Motta-Castro ARC; Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.; Oswaldo Cruz Foundation, Campo Grande, MS, Brazil.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2020 Sep; Vol. 129 (3), pp. 768-774. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article
MeSH Terms :
HTLV-I Infections/*diagnosis
Human T-lymphotropic virus 1/*isolation & purification
Proviruses/*isolation & purification
Real-Time Polymerase Chain Reaction/*methods
Viral Load/*methods
Adult ; DNA, Viral/genetics ; Disease Progression ; Genome, Viral/genetics ; HTLV-I Infections/blood ; HTLV-I Infections/virology ; Human T-lymphotropic virus 1/genetics ; Humans ; Leukocytes, Mononuclear/virology ; Middle Aged ; Oligonucleotides/chemical synthesis ; Oligonucleotides/genetics ; Prognosis ; Proviruses/genetics ; Real-Time Polymerase Chain Reaction/standards ; Viral Load/standards
Czasopismo naukowe
Tytuł :
HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling.
Autorzy :
Higuchi Y; Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8501, Japan.; Department of Hematology, Rheumatology, and Infectious Disease, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8555, Japan.
Yasunaga JI; Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8501, Japan; .; Department of Hematology, Rheumatology, and Infectious Disease, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8555, Japan.
Mitagami Y; Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8501, Japan.
Tsukamoto H; Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8555, Japan.
Nakashima K; Department of Pathology, School of Medicine, Kurume University, Kurume, Fukuoka 830-0011, Japan.
Ohshima K; Department of Pathology, School of Medicine, Kurume University, Kurume, Fukuoka 830-0011, Japan.
Matsuoka M; Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8501, Japan.; Department of Hematology, Rheumatology, and Infectious Disease, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8555, Japan.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 16; Vol. 117 (24), pp. 13740-13749. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basic-Leucine Zipper Transcription Factors/*immunology
HTLV-I Infections/*immunology
Human T-lymphotropic virus 1/*immunology
Interleukin-6/*immunology
Lymphoma/*virology
Retroviridae Proteins/*immunology
Animals ; Basic-Leucine Zipper Transcription Factors/genetics ; Cell Differentiation ; Cell Proliferation ; HTLV-I Infections/genetics ; HTLV-I Infections/pathology ; HTLV-I Infections/virology ; Host-Pathogen Interactions ; Human T-lymphotropic virus 1/genetics ; Human T-lymphotropic virus 1/physiology ; Humans ; Interleukin-10/genetics ; Interleukin-10/immunology ; Interleukin-6/genetics ; Lymphoma/genetics ; Lymphoma/immunology ; Lymphoma/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Retroviridae Proteins/genetics ; T-Lymphocytes, Regulatory/immunology
Czasopismo naukowe
Tytuł :
Structural basis of host protein hijacking in human T-cell leukemia virus integration.
Autorzy :
Bhatt V; The Hormel Institute, University of Minnesota, 801 16th Avenue N.E., Austin, MN, 55912, USA.; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.
Shi K; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Salamango DJ; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Moeller NH; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Pandey KK; Department of Molecular Microbiology and Immunology, Saint Louis University, 1100 S. Grand Boulevard, St. Louis, MO, 63104, USA.
Bera S; Department of Molecular Microbiology and Immunology, Saint Louis University, 1100 S. Grand Boulevard, St. Louis, MO, 63104, USA.
Bohl TE; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Kurniawan F; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Orellana K; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Zhang W; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.; Characterization Facility, College of Science and Engineering, University of Minnesota, 100 Union Street S.E., Minneapolis, MN, 55455, USA.
Grandgenett DP; Department of Molecular Microbiology and Immunology, Saint Louis University, 1100 S. Grand Boulevard, St. Louis, MO, 63104, USA.
Harris RS; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA.; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA.; Howard Hughes Medical Institute, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA.
Sundborger-Lunna AC; The Hormel Institute, University of Minnesota, 801 16th Avenue N.E., Austin, MN, 55912, USA. .; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA. .
Aihara H; Masonic Cancer Center, University of Minnesota, 2231 6th Street S.E., Minneapolis, MN, 55455, USA. .; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street S.E., Minneapolis, MN, 55455, USA. .; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street S.E., Minneapolis, MN, 55455, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 19; Vol. 11 (1), pp. 3121. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Host-Pathogen Interactions/*genetics
Human T-lymphotropic virus 1/*genetics
Integrases/*metabolism
Protein Phosphatase 2/*genetics
Viral Proteins/*metabolism
Virus Integration/*genetics
Cryoelectron Microscopy ; DNA, Viral/metabolism ; HEK293 Cells ; Human T-lymphotropic virus 1/enzymology ; Humans ; Integrases/ultrastructure ; Models, Molecular ; Point Mutation ; Protein Binding/genetics ; Protein Phosphatase 2/metabolism ; Protein Phosphatase 2/ultrastructure ; Viral Proteins/ultrastructure
Czasopismo naukowe
Tytuł :
Central nervous system infiltration by HTLV-1-associated T-cell leukemia/lymphoma in an AIDS patient.
Autorzy :
Zago LBR; Universidade Federal do Triângulo Mineiro, Hospital de Clínicas, Serviço de Hematologia e Hemoterapia, Uberaba, MG, Brasil.
Silva VAD; Universidade Federal do Triângulo Mineiro, Hospital de Clínicas, Serviço de Hematologia e Hemoterapia, Uberaba, MG, Brasil.; Universidade Federal do Triângulo Mineiro, Hospital de Clínicas, Laboratório de Citometria de Fluxo, Uberaba, MG, Brasil.
Vito FB; Universidade Federal do Triângulo Mineiro, Hospital de Clínicas, Laboratório de Citometria de Fluxo, Uberaba, MG, Brasil.
Oliveira LR; Universidade Federal do Triângulo Mineiro, Hospital de Clínicas, Serviço de Hematologia e Hemoterapia, Uberaba, MG, Brasil.
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Źródło :
Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2020 Jun 12; Vol. 53, pp. e20200060. Date of Electronic Publication: 2020 Jun 12 (Print Publication: 2020).
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Acquired Immunodeficiency Syndrome/*complications
Central Nervous System/*microbiology
Human T-lymphotropic virus 1/*isolation & purification
Leukemia-Lymphoma, Adult T-Cell/*diagnosis
Lymphoma/*diagnosis
AIDS-Related Opportunistic Infections ; Central Nervous System/pathology ; Female ; Human T-lymphotropic virus 1/genetics ; Humans ; Leukemia-Lymphoma, Adult T-Cell/microbiology ; Leukemia-Lymphoma, Adult T-Cell/pathology ; Middle Aged
Czasopismo naukowe
Tytuł :
The reasons to include the serology of human T-lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in the clinical follow-up of patients with viral hepatitis B and C in Brazil.
Autorzy :
Campos KR; Laboratório de Pesquisa em HTLV, Centro de Imunologia, Instituto Adolfo Lutz, Coordenadoria de Controle de Doenças, Secretaria de Estado da Saúde, São Paulo, SP, Brasil.
Alves FA; Laboratório de Pesquisa em HTLV, Centro de Imunologia, Instituto Adolfo Lutz, Coordenadoria de Controle de Doenças, Secretaria de Estado da Saúde, São Paulo, SP, Brasil.
Lemos MF; Laboratório de Hepatites Virais, Centro de Virologia, Instituto Adolfo Lutz, Coordenadoria de Controle de Doenças, Secretaria de Estado da Saúde, São Paulo, SP, Brasil.
Moreira RC; Laboratório de Hepatites Virais, Centro de Virologia, Instituto Adolfo Lutz, Coordenadoria de Controle de Doenças, Secretaria de Estado da Saúde, São Paulo, SP, Brasil.
Marcusso RMN; Ambulatório de HTLV, Serviço de Neurologia Clínica, Instituto de Infectologia Emilio Ribas (IIER), São Paulo, SP, Brasil.
Caterino-de-Araujo A; Laboratório de Pesquisa em HTLV, Centro de Imunologia, Instituto Adolfo Lutz, Coordenadoria de Controle de Doenças, Secretaria de Estado da Saúde, São Paulo, SP, Brasil.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 May 26; Vol. 14 (5), pp. e0008245. Date of Electronic Publication: 2020 May 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Human T-lymphotropic virus 1*
Human T-lymphotropic virus 2*
HTLV-I Infections/*complications
HTLV-II Infections/*complications
Hepatitis B/*complications
Hepatitis C/*complications
Brazil/epidemiology ; Coinfection ; HTLV-I Infections/epidemiology ; HTLV-II Infections/epidemiology ; Hepatitis B/epidemiology ; Hepatitis C/epidemiology ; Humans ; Viral Load
Czasopismo naukowe
Tytuł :
RNF8 Dysregulation and Down-regulation During HTLV-1 Infection Promote Genomic Instability in Adult T-Cell Leukemia.
Autorzy :
Zhi H; Department of Microbiology and Immunology Uniformed Services University of the Health Sciences Bethesda, MD, United States of America.
Guo X; Department of Microbiology and Molecular Cell Biology The Leroy T. Canoles Jr Cancer Research Center Eastern Virginia Medical School Norfolk, VA, United States of America.
Ho YK; Department of Microbiology and Immunology Uniformed Services University of the Health Sciences Bethesda, MD, United States of America.
Pasupala N; Department of Microbiology and Immunology Uniformed Services University of the Health Sciences Bethesda, MD, United States of America.
Engstrom HAA; Department of Microbiology and Molecular Cell Biology The Leroy T. Canoles Jr Cancer Research Center Eastern Virginia Medical School Norfolk, VA, United States of America.
Semmes OJ; Department of Microbiology and Molecular Cell Biology The Leroy T. Canoles Jr Cancer Research Center Eastern Virginia Medical School Norfolk, VA, United States of America.
Giam CZ; Department of Microbiology and Immunology Uniformed Services University of the Health Sciences Bethesda, MD, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 May 26; Vol. 16 (5), pp. e1008618. Date of Electronic Publication: 2020 May 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA-Binding Proteins/*immunology
Down-Regulation/*immunology
Genomic Instability/*immunology
HTLV-I Infections/*immunology
Human T-lymphotropic virus 1/*immunology
Leukemia-Lymphoma, Adult T-Cell/*immunology
Neoplasm Proteins/*immunology
Ubiquitin-Protein Ligases/*immunology
DNA Breaks, Double-Stranded ; DNA Repair/genetics ; DNA Repair/immunology ; DNA-Binding Proteins/genetics ; Gene Products, tax/genetics ; Gene Products, tax/immunology ; HTLV-I Infections/genetics ; HTLV-I Infections/pathology ; HeLa Cells ; Human T-lymphotropic virus 1/genetics ; Humans ; Leukemia-Lymphoma, Adult T-Cell/genetics ; Leukemia-Lymphoma, Adult T-Cell/pathology ; Neoplasm Proteins/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
An RNA pseudoknot stimulates HTLV-1 pro-pol programmed -1 ribosomal frameshifting.
Autorzy :
Thulson E; Department of Chemistry and Biochemistry, Fort Lewis College, Durango, Colorado 81301, USA.
Hartwick EW; Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA.; RNA Bioscience Initiative, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA.
Cooper-Sansone A; Department of Chemistry and Biochemistry, Fort Lewis College, Durango, Colorado 81301, USA.
Williams MAC; Department of Chemistry and Biochemistry, Fort Lewis College, Durango, Colorado 81301, USA.
Soliman ME; Department of Chemistry and Biochemistry, Loyola Marymount University, Los Angeles, California 90045, USA.
Robinson LK; Department of Chemistry and Biochemistry, Loyola Marymount University, Los Angeles, California 90045, USA.
Kieft JS; Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA.; RNA Bioscience Initiative, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA.
Mouzakis KD; Department of Chemistry and Biochemistry, Loyola Marymount University, Los Angeles, California 90045, USA.
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Źródło :
RNA (New York, N.Y.) [RNA] 2020 Apr; Vol. 26 (4), pp. 512-528. Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Frameshifting, Ribosomal*
Human T-lymphotropic virus 1/*genetics
RNA, Messenger/*genetics
Gene Expression Regulation, Viral ; Human T-lymphotropic virus 1/metabolism ; Nucleotide Motifs ; RNA, Messenger/chemistry ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
HTLV-1 infection and health outcomes.
Autorzy :
Song M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA.
Piazuelo MB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Camargo MC; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA. Electronic address: .
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2020 Apr; Vol. 20 (4), pp. 406-407.
Typ publikacji :
Letter; Comment
MeSH Terms :
HTLV-I Infections*
Human T-lymphotropic virus 1*
Epidemiologic Studies ; Humans ; Outcome Assessment, Health Care
Opinia redakcyjna
Tytuł :
HTLV-1 infection and health outcomes.
Autorzy :
Ramos JM; Internal Medicine Department, General University Hospital of Alicante, Alicante, Spain; Infectious Disease Unit, Miguel Hernandez University, Elche, Spain.
de Mendoza C; Laboratory of Internal Medicine, Puerta de Hierro Research Institute, Madrid, Spain; Internal Medicine Department, Puerta de Hierro University Hospital, Madrid Spain; Microbiology Department, San Pablo-CEU University, Madrid, Spain.
Soriano V; UNIR Health Sciences School and Medical Center, Madrid 28040, Spain. Electronic address: .
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Corporate Authors :
Spanish HTLV Network
Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2020 Apr; Vol. 20 (4), pp. 407-408.
Typ publikacji :
Letter; Comment
MeSH Terms :
HTLV-I Infections*
Human T-lymphotropic virus 1*
Epidemiologic Studies ; Humans ; Outcome Assessment, Health Care
Opinia redakcyjna
Tytuł :
Retroviral sero-reactivity in LGL leukaemia patients and family members.
Autorzy :
Nyland SB; Division of Hematology/Oncology, Department of Medicine, UVA Cancer Center, University of Virginia, Charlottesville, VA, USA.
Feith DJ; Division of Hematology/Oncology, Department of Medicine, UVA Cancer Center, University of Virginia, Charlottesville, VA, USA.
Poss M; Division of Hematology/Oncology, Department of Medicine, UVA Cancer Center, University of Virginia, Charlottesville, VA, USA.
Olson TL; Division of Hematology/Oncology, Department of Medicine, UVA Cancer Center, University of Virginia, Charlottesville, VA, USA.
Krissinger DJ; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA.
Poiesz BJ; Division of Hematology/Oncology, Department of Medicine, State University of New York, Upstate Medical University, Syracuse, NY, USA.
Ruscetti FW; MAR Consulting Inc, Carlsbad, CA, USA.
Loughran TP Jr; Division of Hematology/Oncology, Department of Medicine, UVA Cancer Center, University of Virginia, Charlottesville, VA, USA.
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Źródło :
British journal of haematology [Br J Haematol] 2020 Feb; Vol. 188 (4), pp. 522-527. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Envelope Protein gp41*/blood
HIV Envelope Protein gp41*/immunology
HIV-1*/immunology
HIV-1*/metabolism
Human T-lymphotropic virus 1*/immunology
Human T-lymphotropic virus 1*/metabolism
Human T-lymphotropic virus 2*/immunology
Human T-lymphotropic virus 2*/metabolism
Leukemia, Large Granular Lymphocytic*/blood
Leukemia, Large Granular Lymphocytic*/immunology
T-Lymphocytes, Cytotoxic*/immunology
T-Lymphocytes, Cytotoxic*/metabolism
Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
Reduced-intensity haploidentical peripheral blood stem cell transplantation using low-dose thymoglobulin for aggressive adult T cell leukemia/lymphoma patients in non-complete remission.
Autorzy :
Hirosawa M; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Yamaguchi T; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Tanaka A; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Kominato Y; Department of Legal Medicine, Graduate School of Medicine, Gunma University, Maebashi, Japan.
Higashi T; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Morimoto H; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan.
Tsukada J; Hematology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8556, Japan. .
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Źródło :
Annals of hematology [Ann Hematol] 2020 Mar; Vol. 99 (3), pp. 599-607. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Human T-lymphotropic virus 1*
Leukemia-Lymphoma, Adult T-Cell*/blood
Leukemia-Lymphoma, Adult T-Cell*/therapy
Peripheral Blood Stem Cell Transplantation*
Transplantation Conditioning*
Antilymphocyte Serum/*administration & dosage
Aged ; Allografts ; Antibodies, Monoclonal, Humanized/administration & dosage ; Female ; Follow-Up Studies ; Humans ; Male ; Melphalan/administration & dosage ; Middle Aged ; Time Factors ; Vidarabine/administration & dosage ; Vidarabine/analogs & derivatives ; Viral Load ; Whole-Body Irradiation
Czasopismo naukowe
Tytuł :
Use of cerebrospinal fluid CXCL10 and neopterin as biomarkers in HTLV-1-associated myelopathy/tropical spastic paraparesis treated with steroids.
Autorzy :
Yamauchi J; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan.
Sato T; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan.
Yagishita N; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan.
Araya N; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan.
Hasegawa D; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan.
Tsutsumi S; Department of Advanced Medical Innovation, St. Marianna University Graduate School of Medicine, Kawasaki, Japan.
Nagasaka M; Department of Advanced Medical Innovation, St. Marianna University Graduate School of Medicine, Kawasaki, Japan.; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA.
Coler-Reilly A; Department of Advanced Medical Innovation, St. Marianna University Graduate School of Medicine, Kawasaki, Japan.
Inoue E; Medical Informatics, St. Marianna University School of Medicine, Kanagawa, Japan.
Takata A; Department of Preventive Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Hasegawa Y; Department of Neurology, St. Marianna University School of Medicine, Kawasaki, Japan.
Yamano Y; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan .
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Źródło :
Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2020 Mar; Vol. 91 (3), pp. 321-323. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Human T-lymphotropic virus 1*
Chemokine CXCL10/*cerebrospinal fluid
Neopterin/*cerebrospinal fluid
Paraparesis, Tropical Spastic/*cerebrospinal fluid
Paraparesis, Tropical Spastic/*drug therapy
Prednisolone/*therapeutic use
Biomarkers/cerebrospinal fluid ; Glucocorticoids/therapeutic use ; Humans ; Retrospective Studies ; Treatment Outcome
Raport

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