Autor: "Husebye ES" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Autoimmune regulator and self-tolerance - molecular and clinical aspects.
Autorzy:: Abramson J; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel.
Husebye ES; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medicine, Haukeland University Hospital, Bergen, Norway.; Pokaż więcej
Źródło:: Immunological reviews [Immunol Rev] 2016 May; Vol. 271 (1), pp. 127-40.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Clonal Selection, Antigen-Mediated*
Polyendocrinopathies, Autoimmune/*genetics
T-Lymphocytes, Regulatory/*physiology
Transcription Factors/*genetics
Animals ; Autoantigens/immunology ; Autoimmunity ; Central Tolerance ; Forkhead Transcription Factors/metabolism ; Humans ; Transcription Factors/metabolism ; AIRE Protein
SCR Disease Name:: Autoimmune polyendocrinopathy syndrome, type 1

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Autorzy:: Chuprin A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Avin A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Goldfarb Y; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Herzig Y; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Levi B; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Jacob A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Sela A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Katz S; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Grossman M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
Guyon C; Department of Immunology, Institut Cochin, INSERM U1016, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Rathaus M; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
Cohen HY; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
Sagi I; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
Giraud M; Department of Immunology, Institut Cochin, INSERM U1016, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
McBurney MW; Ottawa Hospital Research Institute, Ottawa, Canada.
Husebye ES; Department of Clinical Science, University of Bergen, Bergen, Norway.
Abramson J; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2015 Jul; Vol. 16 (7), pp. 737-45. Date of Electronic Publication: 2015 May 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Central Tolerance/*immunology
Sirtuin 1/*immunology
Transcription Factors/*immunology
Transcriptional Activation/*immunology
Acetylation ; Animals ; Antigens/immunology ; Central Tolerance/genetics ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Flow Cytometry ; HEK293 Cells ; Humans ; Immunoblotting ; Interleukin Receptor Common gamma Subunit/deficiency ; Interleukin Receptor Common gamma Subunit/genetics ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mice, Transgenic ; Oligonucleotide Array Sequence Analysis ; Organ Specificity/immunology ; Protein Binding/immunology ; Reverse Transcriptase Polymerase Chain Reaction ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; Thymus Gland/cytology ; Thymus Gland/immunology ; Thymus Gland/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcriptome/immunology ; AIRE Protein