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Wyszukujesz frazę ""Hydroxychloroquine"" wg kryterium: Temat


Tytuł :
Hydroxychloroquine can potentially interfere with immune function in COVID-19 patients: Mechanisms and insights.
Autorzy :
Devarajan A; UCLA Cardiac Arrhythmia Center, University of California, Los Angeles, CA, USA; Neurocardiology Research Center of Excellence, University of California, Los Angeles, CA, USA. Electronic address: .
Vaseghi M; UCLA Cardiac Arrhythmia Center, University of California, Los Angeles, CA, USA; Neurocardiology Research Center of Excellence, University of California, Los Angeles, CA, USA.
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Źródło :
Redox biology [Redox Biol] 2021 Jan; Vol. 38, pp. 101810. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Antiviral Agents*/adverse effects
Antiviral Agents*/therapeutic use
Autophagic Cell Death*/drug effects
Autophagic Cell Death*/immunology
COVID-19*/drug therapy
COVID-19*/epidemiology
COVID-19*/immunology
COVID-19*/pathology
Hydroxychloroquine*/adverse effects
Hydroxychloroquine*/therapeutic use
Pandemics*
Antigen Presentation/*drug effects
SARS-CoV-2/*immunology
Humans ; Oxidation-Reduction/drug effects
Czasopismo naukowe
Tytuł :
Antimalarials as Antivirals for COVID-19: Believe it or Not!
Autorzy :
Saha BK; Pulmonary and Critical Care Medicine, Ozarks Medical Center, West Plains, Missouri. Electronic address: .
Bonnier A; Division of Critical Care Nursing, Goldfarb School of Nursing, Barnes Jewish College, St. Louis, Missouri.
Chong W; Division of Pulmonary and Critical Care Medicine, Albany Medical Center College, Albany, New York.
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Źródło :
The American journal of the medical sciences [Am J Med Sci] 2020 Dec; Vol. 360 (6), pp. 618-630. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antimalarials/*therapeutic use
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
Chloroquine/*therapeutic use
Hydroxychloroquine/*therapeutic use
SARS-CoV-2/*drug effects
Animals ; Antimalarials/pharmacokinetics ; Antimalarials/pharmacology ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/pharmacology ; Chlorocebus aethiops ; Chloroquine/pharmacokinetics ; Chloroquine/pharmacology ; Humans ; Hydroxychloroquine/pharmacokinetics ; Hydroxychloroquine/pharmacology ; Vero Cells
Czasopismo naukowe
Tytuł :
Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID-19 Infection.
Autorzy :
Nicol MR; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.
Joshi A; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Rizk ML; Quantitative Pharmacology and Pharmacometrics, Merck & Co Inc, Kenilworth, New Jersey, USA.
Sabato PE; Quantitative Pharmacology and Pharmacometrics, Merck & Co Inc, Kenilworth, New Jersey, USA.
Savic RM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.
Wesche D; Certara, Princeton, New Jersey, USA.
Zheng JH; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Cook J; Clinical Pharmacology Department, Global Product Development, Pfizer Inc, Groton, Connecticut, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 Dec; Vol. 108 (6), pp. 1135-1149. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
Chloroquine/*pharmacology
Chloroquine/*therapeutic use
Hydroxychloroquine/*pharmacology
Hydroxychloroquine/*therapeutic use
Age Factors ; Aging ; Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Chloroquine/adverse effects ; Chloroquine/pharmacokinetics ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Drug Interactions ; Drug Therapy, Combination ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/pharmacokinetics ; Liver Failure/epidemiology ; Malaria/drug therapy ; Prospective Studies ; Renal Insufficiency/epidemiology ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Rheumotologitsts' view on the use of hydroxychloroquine to treat COVID-19.
Autorzy :
Sun X; Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Ni Y; Department of Imaging & Pathology, Faculty of Medicine, KU Leuven, Belgium.
Zhang M; Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2020 Dec; Vol. 9 (1), pp. 830-832.
Typ publikacji :
Letter
MeSH Terms :
Antimalarials*/administration & dosage
Antimalarials*/adverse effects
Antimalarials*/therapeutic use
Antirheumatic Agents*/administration & dosage
Antirheumatic Agents*/adverse effects
Antirheumatic Agents*/therapeutic use
Antiviral Agents*/administration & dosage
Antiviral Agents*/adverse effects
Antiviral Agents*/therapeutic use
Hydroxychloroquine*/administration & dosage
Hydroxychloroquine*/adverse effects
Hydroxychloroquine*/therapeutic use
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Pneumonia, Viral/*drug therapy
COVID-19 ; Clinical Trials as Topic ; Coronavirus Infections/epidemiology ; Humans ; Interdisciplinary Communication ; Pandemics ; Pneumonia, Viral/epidemiology ; Rheumatologists ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Opinia redakcyjna
Tytuł :
Acute generalized exanthematous pustulosis and Stevens-Johnson syndrome overlap due to hydroxychloroquine: a case report.
Autorzy :
Coleman I; Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA. .
Ruiz G; Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA.
Brahmbhatt S; Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA.
Ackerman L; Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA.; Banner University Medical Center - Phoenix Division of Dermatology, University of Arizona College of Medicine, Phoenix, 475 North 5th Street, Phoenix, AZ, 85004, USA.
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Źródło :
Journal of medical case reports [J Med Case Rep] 2020 Nov 03; Vol. 14 (1), pp. 210. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Acute Generalized Exanthematous Pustulosis*/diagnosis
Acute Generalized Exanthematous Pustulosis*/etiology
Acute Generalized Exanthematous Pustulosis*/physiopathology
Acute Generalized Exanthematous Pustulosis*/therapy
Hydroxychloroquine*/administration & dosage
Hydroxychloroquine*/adverse effects
Stevens-Johnson Syndrome*/diagnosis
Stevens-Johnson Syndrome*/etiology
Stevens-Johnson Syndrome*/physiopathology
Stevens-Johnson Syndrome*/therapy
Coronavirus Infections/*epidemiology
Immunoglobulins, Intravenous/*administration & dosage
Methylprednisolone/*administration & dosage
Pneumonia, Viral/*epidemiology
Sarcoidosis/*drug therapy
Aged ; Antimalarials/administration & dosage ; Antimalarials/adverse effects ; Biopsy/methods ; COVID-19 ; Female ; Humans ; Immunologic Factors ; Pandemics ; Skin/pathology ; Skin Diseases/drug therapy ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Hydroxychloroquine in COVID-19 Therapy: Protection Versus Proarrhythmia.
Autorzy :
Stremmel C; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, 54187Ludwig-Maximilians University, Munich, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Kellnar A; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, 54187Ludwig-Maximilians University, Munich, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
Massberg S; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, 54187Ludwig-Maximilians University, Munich, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; COVID-19 Registry of the Ludwig-Maximilians University (CORKUM), Munich, Germany.
Kääb S; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, 54187Ludwig-Maximilians University, Munich, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; COVID-19 Registry of the Ludwig-Maximilians University (CORKUM), Munich, Germany.
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Źródło :
Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2020 Nov; Vol. 25 (6), pp. 497-502. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Coronavirus Infections/*drug therapy
Hydroxychloroquine/*therapeutic use
Pneumonia, Viral/*drug therapy
Arrhythmias, Cardiac/chemically induced ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/immunology ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/pharmacology ; Pandemics ; Pneumonia, Viral/immunology ; Randomized Controlled Trials as Topic ; Retinal Diseases/chemically induced ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Hydroxychloroquine in Hospitalized Patients with COVID-19: Real-World Experience Assessing Mortality.
Autorzy :
Annie FH; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, USA.
Sirbu C; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, USA.
Frazier KR; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, USA.
Broce M; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, USA.
Lucas BD Jr; Charleston Area Medical Center Health Education and Research Institute, Charleston, West Virginia, USA.
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Źródło :
Pharmacotherapy [Pharmacotherapy] 2020 Nov; Vol. 40 (11), pp. 1072-1081.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Repositioning*
Off-Label Use*
COVID-19/*drug therapy
COVID-19/*mortality
Hospitalization/*statistics & numerical data
Hydroxychloroquine/*therapeutic use
Aged ; Clinical Trials as Topic ; Cohort Studies ; Databases, Factual ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/adverse effects ; Male ; Middle Aged ; Mortality/trends ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Effects of Hydroxychloroquine on Covid-19 in Intensive Care Unit Patients: Preliminary Results.
Autorzy :
Lopez A; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France. Electronic address: .
Duclos G; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France.
Pastene B; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France.
Bezulier K; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France.
Guilhaumou R; Service de Pharmacologie Clinique et Pharmacovigilance, APHM, Institut de neurosciences des systèmes, Inserm UMR 1106, Université d'Aix-Marseille, France.
Solas C; Aix-Marseille University, APHM, UMR 'Emergence des Pathologies Virales' Inserm 1207 IRD 190, Laboratoire de Pharmacocinétique et Toxicologie, Hôpital La Timone, 13005 Marseille, France.
Zieleskiewicz L; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France; Center for Cardiovascular and Nutrition Research (C2VN) Aix Marseille Université, INSERM, INRA, Marseille, 13005, France.
Leone M; Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Department of Anesthesiology and Intensive Care, Hôpital Nord, Marseille, 13015, France.
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Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2020 Nov; Vol. 56 (5), pp. 106136. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Hydroxychloroquine/*therapeutic use
Pneumonia, Viral/*drug therapy
Anti-Inflammatory Agents/adverse effects ; Anti-Inflammatory Agents/blood ; COVID-19 ; Critical Care ; Female ; Hospital Mortality ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/blood ; Intensive Care Units ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Pandemics ; Preliminary Data ; Retrospective Studies ; SARS-CoV-2 ; Viral Load/drug effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Incidence of arrhythmias and electrocardiographic abnormalities in symptomatic pediatric patients with PCR-positive SARS-CoV-2 infection, including drug-induced changes in the corrected QT interval.
Autorzy :
Samuel S; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York. Electronic address: .
Friedman RA; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
Sharma C; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
Ganigara M; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
Mitchell E; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
Schleien C; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
Blaufox AD; Section of Pediatric Cardiology and; Department of Pediatrics, Cohen Children's Medical Center, Northwell Health System, Donald and Barbara Zucker School of Medicine at Hofstra University, New Hyde Park, New York.
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Źródło :
Heart rhythm [Heart Rhythm] 2020 Nov; Vol. 17 (11), pp. 1960-1966. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Arrhythmias, Cardiac*/diagnosis
Arrhythmias, Cardiac*/epidemiology
Azithromycin*/administration & dosage
Azithromycin*/adverse effects
Coronavirus Infections*/diagnosis
Coronavirus Infections*/drug therapy
Coronavirus Infections*/epidemiology
Coronavirus Infections*/physiopathology
Electrocardiography*/methods
Electrocardiography*/statistics & numerical data
Hydroxychloroquine*/administration & dosage
Hydroxychloroquine*/adverse effects
Long QT Syndrome*/chemically induced
Long QT Syndrome*/diagnosis
Pandemics*
Pneumonia, Viral*/diagnosis
Pneumonia, Viral*/drug therapy
Pneumonia, Viral*/epidemiology
Pneumonia, Viral*/physiopathology
Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/adverse effects ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Child ; Clinical Laboratory Techniques/methods ; Female ; Humans ; Incidence ; Male ; New York City/epidemiology ; Outcome and Process Assessment, Health Care ; Retrospective Studies ; Risk Factors ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials.
Autorzy :
Lewis K; Department of Medicine, McMaster University, Hamilton, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Chaudhuri D; Department of Medicine, McMaster University, Hamilton, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Alshamsi F; Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Carayannopoulos L; Department of Medicine, McMaster University, Hamilton, Canada.
Dearness K; St. Joseph's Healthcare Hamilton, Hamilton, Canada.
Chagla Z; Department of Medicine, McMaster University, Hamilton, Canada.
Alhazzani W; Department of Medicine, McMaster University, Hamilton, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
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Corporate Authors :
GUIDE Group
Źródło :
PloS one [PLoS One] 2021 Jan 06; Vol. 16 (1), pp. e0244778. Date of Electronic Publication: 2021 Jan 06 (Print Publication: 2021).
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
COVID-19/*drug therapy
Hydroxychloroquine/*adverse effects
Hydroxychloroquine/*therapeutic use
Antibiotic Prophylaxis/methods ; Antiviral Agents/therapeutic use ; COVID-19/metabolism ; Humans ; Hydroxychloroquine/metabolism ; Pre-Exposure Prophylaxis/methods ; Randomized Controlled Trials as Topic ; SARS-CoV-2/pathogenicity
Czasopismo naukowe
Tytuł :
Hydroxychloroquine for the treatment and prophylaxis of COVID-19: The journey so far and the road ahead.
Autorzy :
Singh H; Dept. of Pharmacology, Government Medical College and Hospital, Chandigarh, 160030, India.
Chauhan P; Dept. of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Kakkar AK; Dept. of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jan 05; Vol. 890, pp. 173717. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
SARS-CoV-2*
COVID-19/*drug therapy
COVID-19/*prevention & control
Hydroxychloroquine/*therapeutic use
Federal Government ; Government Agencies ; Humans ; Hydroxychloroquine/adverse effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?
Autorzy :
Çelik HG; Department of Cardiology, American Hospital, Istanbul, Turkey.
Keske Ş; Department of Infectious Diseases, American Hospital, Istanbul, Turkey.
Şener Ü; Department of Pharmacy, American Hospital, Istanbul, Turkey.
Tekbaş M; Department of Pharmacy, Koç University Hospital, Istanbul, Turkey.
Kapmaz M; Koç University İş Bank Research Center for Infectious Diseases, Istanbul, Turkey.
Şahin ŞT; Department of Cardiology, American Hospital, Istanbul, Turkey.
Özyıldırım A; Department of Pharmacy, American Hospital, Istanbul, Turkey.
Aytekin S; Department of Cardiology, Koç University School of Medicine, Istanbul, Turkey.
Aytekin V; Department of Cardiology, Koç University School of Medicine, Istanbul, Turkey.
Ergönül Ö; Koç University İş Bank Research Center for Infectious Diseases, Istanbul, Turkey. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Jan; Vol. 102, pp. 389-391. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
SARS-CoV-2*
COVID-19/*drug therapy
Hydroxychloroquine/*adverse effects
Influenza, Human/*drug therapy
Long QT Syndrome/*chemically induced
Adult ; Aged ; Aged, 80 and over ; Azithromycin/administration & dosage ; Electrocardiography/drug effects ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Male ; Middle Aged ; Oseltamivir/adverse effects ; Oseltamivir/therapeutic use
Czasopismo naukowe
Tytuł :
Why G6PD Deficiency Should Be Screened Before COVID-19 Treatment With Hydroxychloroquine?
Autorzy :
Oymak Y; Departments of Pediatric Hematology and Oncology.
Karapinar TH; Departments of Pediatric Hematology and Oncology.
Devrim İ; Pediatric Infectious Diseases, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
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Źródło :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2021 Jan; Vol. 43 (1), pp. 35-36.
Typ publikacji :
Letter
MeSH Terms :
COVID-19/*complications
COVID-19/*drug therapy
Glucosephosphate Dehydrogenase Deficiency/*complications
Glucosephosphate Dehydrogenase Deficiency/*diagnosis
Hydroxychloroquine/*adverse effects
Hydroxychloroquine/*therapeutic use
Hemolysis/drug effects ; Humans ; Hydroxychloroquine/administration & dosage
SCR Protocol :
COVID-19 drug treatment
Opinia redakcyjna
Tytuł :
An evaluation of co-use of chloroquine or hydroxychloroquine plus azithromycin on cardiac outcomes: A pharmacoepidemiological study to inform use during the COVID19 pandemic.
Autorzy :
Vouri SM; Department of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, FL, USA; Center for Drug Evaluation and Safety, University of Florida, Gainesville, FL, USA; University of Florida Health Physicians, Gainesville, FL, USA.
Thai TN; Department of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, FL, USA.
Winterstein AG; Department of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, FL, USA; Center for Drug Evaluation and Safety, University of Florida, Gainesville, FL, USA. Electronic address: .
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Źródło :
Research in social & administrative pharmacy : RSAP [Res Social Adm Pharm] 2021 Jan; Vol. 17 (1), pp. 2012-2017. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Azithromycin/*administration & dosage
COVID-19/*epidemiology
Chloroquine/*administration & dosage
Heart Diseases/*epidemiology
Hydroxychloroquine/*administration & dosage
Pharmacoepidemiology/*methods
Adolescent ; Adult ; Aged ; Azithromycin/adverse effects ; COVID-19/drug therapy ; Chloroquine/adverse effects ; Cohort Studies ; Drug Therapy, Combination/adverse effects ; Female ; Heart Diseases/chemically induced ; Humans ; Hydroxychloroquine/adverse effects ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Arrhythmic safety of hydroxychloroquine in COVID-19 patients from different clinical settings.
Autorzy :
Gasperetti A; Heart Rhythm Center, Centro Cardiologico Monzino, IRCCS, Milan, Italy.; University Heart Center, University Hospital Zürich, Zürich, Switzerland.
Biffi M; Unit of Cardiology, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, Bologna, Italy.
Duru F; University Heart Center, University Hospital Zürich, Zürich, Switzerland.
Schiavone M; Department of Cardiology, ASST-Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Ziacchi M; Unit of Cardiology, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, Bologna, Italy.
Mitacchione G; Department of Cardiology, ASST-Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Lavalle C; Department of Cardiovascular Disease, Policlinico Umberto I Hospital, Rome, Italy.
Saguner A; University Heart Center, University Hospital Zürich, Zürich, Switzerland.
Lanfranchi A; Department of Cardiology, ASST-Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Casalini G; III Division of Infectious Diseases, ASST-Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Italy.
Tocci M; Department of Cardiovascular Disease, Policlinico Umberto I Hospital, Rome, Italy.
Fabbricatore D; Division of Cardiology, Spedali Civili Hospital, Brescia, Italy.
Salghetti F; Division of Cardiology, Spedali Civili Hospital, Brescia, Italy.
Mariani MV; Department of Cardiovascular Disease, Policlinico Umberto I Hospital, Rome, Italy.
Busana M; Department of Anesthesiology, Emergency and Intensive Care Medicine, University of Göttingen, Göttingen, Germany.
Bellia A; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Cogliati CB; Department of Internal Medicine, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Viale P; Heart Rhythm Center, Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Unit of Infectious Diseases, Department of Medical and Surgical Sciences, S. Orsola Hospital, University of Bologna, Bologna, Italy.
Antinori S; III Division of Infectious Diseases, ASST-Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Italy.
Galli M; III Division of Infectious Diseases, ASST-Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Italy.
Galiè N; Unit of Cardiology, Department of Experimental, Diagnostic and Specialty Medicine-DIMES, University of Bologna, Bologna, Italy.
Tondo C; Heart Rhythm Center, Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Forleo GB; Department of Cardiology, ASST-Fatebenefratelli Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy.
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Źródło :
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2020 Dec 23; Vol. 22 (12), pp. 1855-1863.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Electrocardiography*
Arrhythmias, Cardiac/*virology
COVID-19/*drug therapy
Hydroxychloroquine/*administration & dosage
Arrhythmias, Cardiac/chemically induced ; COVID-19/epidemiology ; Female ; Humans ; Hydroxychloroquine/adverse effects ; Italy/epidemiology ; Male ; Middle Aged ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Hydroxychloroquine and COVID-19 - A narrative review.
Autorzy :
Bajpai J; Department of Respiratory Medicine, King George's Medical University, Lucknow, 226003, India.
Pradhan A; Department of Cardiology, King George's Medical University, Lucknow, 226003, India.
Singh A; Department of Medicine, King George's Medical University, Lucknow, 226003, India.
Kant S; Department of Respiratory Medicine, King George's Medical University, Lucknow, 226003, India. Electronic address: .
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Źródło :
The Indian journal of tuberculosis [Indian J Tuberc] 2020 Dec; Vol. 67 (4S), pp. S147-S154. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
SARS-CoV-2*
COVID-19/*drug therapy
Enzyme Inhibitors/*pharmacology
Hydroxychloroquine/*pharmacology
Enzyme Inhibitors/therapeutic use ; Humans ; Hydroxychloroquine/therapeutic use
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Revisiting the cardiovascular risk of hydroxychloroquine in RA.
Autorzy :
Pers YM; INSERM U1183, Institute for Regenerative Medicine and Biotherapy, CHU Montpellier and University of Montpellier, Montpellier, France. .
Padern G; INSERM U1183, Institute for Regenerative Medicine and Biotherapy, CHU Montpellier and University of Montpellier, Montpellier, France.
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Źródło :
Nature reviews. Rheumatology [Nat Rev Rheumatol] 2020 Dec; Vol. 16 (12), pp. 671-672.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*toxicity
Arthritis, Rheumatoid/*drug therapy
Cardiovascular Diseases/*chemically induced
Hydroxychloroquine/*toxicity
Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents/adverse effects ; Anti-Infective Agents/therapeutic use ; Antimalarials/adverse effects ; Antimalarials/therapeutic use ; Azithromycin/adverse effects ; Azithromycin/therapeutic use ; COVID-19/drug therapy ; COVID-19/epidemiology ; COVID-19/virology ; Cardiovascular Diseases/physiopathology ; Drug Therapy, Combination ; Heart Disease Risk Factors ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; SARS-CoV-2/isolation & purification ; Safety ; Sulfasalazine/adverse effects ; Sulfasalazine/therapeutic use ; Time Factors
Czasopismo naukowe
Tytuł :
A multiscale absorption and transit model for oral delivery of hydroxychloroquine: Pharmacokinetic modeling and intestinal concentration prediction to assess toxicity and drug-induced damage in healthy subjects.
Autorzy :
Kannan R; CFD Research Corporation, Huntsville, Alabama, 35806, USA.
Przekwas A; CFD Research Corporation, Huntsville, Alabama, 35806, USA.
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Źródło :
International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2020 Dec; Vol. 36 (12), pp. e3403. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
COVID-19*/drug therapy
COVID-19*/metabolism
COVID-19*/pathology
Computer Simulation*
Hydroxychloroquine*/adverse effects
Hydroxychloroquine*/pharmacokinetics
Hydroxychloroquine*/therapeutic use
Models, Biological*
SARS-CoV-2*
Administration, Oral ; Healthy Volunteers ; Humans
Czasopismo naukowe
Tytuł :
Causal inference methods for small non-randomized studies: Methods and an application in COVID-19.
Autorzy :
Friedrich S; Department of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073 Göttingen, Germany. Electronic address: .
Friede T; Department of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073 Göttingen, Germany. Electronic address: .
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Źródło :
Contemporary clinical trials [Contemp Clin Trials] 2020 Dec; Vol. 99, pp. 106213. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
COVID-19/*epidemiology
Clinical Trials as Topic/*organization & administration
Hydroxychloroquine/*therapeutic use
Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Causality ; Clinical Trials as Topic/standards ; Humans ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/adverse effects ; Pandemics ; Propensity Score ; SARS-CoV-2 ; Sample Size
Czasopismo naukowe
Tytuł :
No benefit of hydroxychloroquine on SARS-CoV-2 viral load reduction in non-critical hospitalized patients with COVID-19.
Autorzy :
Faíco-Filho KS; Department of Medicine, Discipline of Infectious Diseases, Laboratório de Virologia Clínica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781 - Vila Clementino, São Paulo, SP, 04039-032, Brazil. .
Conte DD; Department of Medicine, Discipline of Infectious Diseases, Laboratório de Virologia Clínica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781 - Vila Clementino, São Paulo, SP, 04039-032, Brazil.
de Souza Luna LK; Department of Medicine, Discipline of Infectious Diseases, Laboratório de Virologia Clínica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781 - Vila Clementino, São Paulo, SP, 04039-032, Brazil.
Carvalho JMA; Department of Medicine, Discipline of Infectious Diseases, Laboratório de Virologia Clínica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781 - Vila Clementino, São Paulo, SP, 04039-032, Brazil.
Perosa AHS; Hospital São Paulo, Universidade Federal de São Paulo, São Paulo, Brazil.
Bellei N; Department of Medicine, Discipline of Infectious Diseases, Laboratório de Virologia Clínica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781 - Vila Clementino, São Paulo, SP, 04039-032, Brazil.
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Źródło :
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2020 Dec; Vol. 51 (4), pp. 1765-1769. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*drug therapy
Hydroxychloroquine/*pharmacology
SARS-CoV-2/*drug effects
Viral Load/*drug effects
Adult ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Male ; Middle Aged ; Prospective Studies ; Young Adult
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe

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