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Wyszukujesz frazę ""Hydroxyurea"" wg kryterium: Temat


Tytuł :
[The relationship between symptom burden and hematologic responses after treatment with interferon/hydroxyurea in patients with polycythemia vera].
Autorzy :
Liu D; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Xu ZF; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Qin TJ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Qu SQ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Sun XJ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Li B; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Pan LJ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
Xiao ZJ; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.
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Źródło :
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi [Zhonghua Xue Ye Xue Za Zhi] 2021 Aug 14; Vol. 42 (8), pp. 635-641.
Typ publikacji :
Journal Article
MeSH Terms :
Hydroxyurea*
Polycythemia Vera*/drug therapy
Female ; Humans ; Interferon-alpha ; Male
Czasopismo naukowe
Tytuł :
Hydroxyurea-induced genital ulcers and erosions: Two case reports.
Autorzy :
Blum AE; Harvard Medical School, Boston, MA, USA.
Tsiaras WG; Harvard Medical School, Boston, MA, USA; Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Kemp JM; Harvard Medical School, Boston, MA, USA; Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: .
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Źródło :
Journal of tissue viability [J Tissue Viability] 2021 Aug; Vol. 30 (3), pp. 462-464. Date of Electronic Publication: 2021 Jun 06.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Hydroxyurea/*adverse effects
Leg Ulcer/*chemically induced
Ulcer/*chemically induced
Aged, 80 and over ; Humans ; Hydroxyurea/administration & dosage ; Male ; Myeloproliferative Disorders/drug therapy ; Polycythemia Vera/drug therapy ; Scrotum
Czasopismo naukowe
Tytuł :
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
Autorzy :
Choi HS; Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Hong J; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Hwang SM; Department of Laboratory, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Lee JH; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Ma Y; Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Kim SA; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Lee JY; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Lee JO; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Bang SM; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea. .
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Źródło :
Annals of hematology [Ann Hematol] 2021 Oct; Vol. 100 (10), pp. 2567-2574. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Neoplasms, Second Primary/*etiology
Polycythemia Vera/*drug therapy
Thrombocythemia, Essential/*drug therapy
Adolescent ; Adult ; Antineoplastic Agents/adverse effects ; Aspirin/therapeutic use ; Child ; Female ; Fibrinolytic Agents/therapeutic use ; Follow-Up Studies ; Humans ; Hydroxyurea/adverse effects ; Leukemia/etiology ; Male ; Polycythemia Vera/complications ; Primary Myelofibrosis/etiology ; Thrombocythemia, Essential/complications ; Thromboembolism/drug therapy ; Thromboembolism/etiology ; Young Adult
Czasopismo naukowe
Tytuł :
Real-Life experience with hydroxyurea in patients with sickle cell disease: Results from the prospective ESCORT-HU cohort study.
Autorzy :
de Montalembert M; Reference Centre for Sickle Cell Disease, Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Voskaridou E; Centre of Excellence in Rare Hematological Disease-Hemoglobinopathies, Laiko General Hospital, Athens, Greece.
Oevermann L; Department of Pediatric Oncology & Hematology, Charité University Medicine, Berlin and Berlin Institute of Health, Berlin, Germany.
Cannas G; Hospices Civils de Lyon, Hôpital Edouard Herriot, Médecine Interne, Centre de Référence Constitutif: Syndromes Drépanocytaires Majeurs, Thalassémies et Autres Pathologies Rares du Globule Rouge et de l'Erythropoïèse, Lyon, France.
Habibi A; Sickle Cell Referral Center, Department of Internal Medicine, Henri-Mondor University Hospital-UPEC, AP-HP, Créteil, France.
Loko G; Centre hospitalier de la Martinique, Fort-de-France, Martinique, France.
Joseph L; Biotherapy Department, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Colombatti R; Department of Woman's and Child's Health, University of Padua, Padua, Italy.
Bartolucci P; Sickle Cell Referral Center, Department of Internal Medicine, Henri-Mondor University Hospital-UPEC, AP-HP, Créteil, France.
Brousse V; Reference Centre for Sickle Cell Disease, Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Galactéros F; Sickle Cell Referral Center, Department of Internal Medicine, Henri-Mondor University Hospital-UPEC, AP-HP, Créteil, France.
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Corporate Authors :
All ESCORT HU Investigators
Źródło :
American journal of hematology [Am J Hematol] 2021 Oct 01; Vol. 96 (10), pp. 1223-1231. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Clinical Trial, Phase IV; Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell/*drug therapy
Antisickling Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Adolescent ; Adult ; Anemia, Sickle Cell/epidemiology ; Antisickling Agents/adverse effects ; Child ; Europe/epidemiology ; Female ; Humans ; Hydroxyurea/adverse effects ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
The Effects of Treatment with Blood Transfusion, Iron Chelation and Hydroxyurea on Puberty, Growth and Spermatogenesis in Sickle Cell Disease (SCD): A short update.
Autorzy :
Soliman AT; Department of Pediatrics, Division of Endocrinology, Hamad General Hospital, Doha, Qatar; Department of Hematology and Oncology, National Centre for Cancer Care and Research, Hamad Medical Corporation, Weill Cornell Medicine- Qatar (WCMCQ). .
Alaaraj N; Department of Pediatrics, Hamad General Hospital, Doha, Qatar. .
Yassin M; Department of Hematology and Oncology, National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar. .
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Źródło :
Acta bio-medica : Atenei Parmensis [Acta Biomed] 2021 Sep 02; Vol. 92 (4), pp. e2021386. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Hydroxyurea*/therapeutic use
Adolescent ; Antisickling Agents ; Blood Transfusion ; Humans ; Iron Chelating Agents ; Male ; Puberty ; Quality of Life ; Spermatogenesis
Czasopismo naukowe
Tytuł :
Hydroxyurea Use Associated with Nonverbal and Executive Skills in Sickle Cell Anemia.
Autorzy :
Tarazi RA; Department of Psychiatry, Drexel University College of Medicine, Philadelphia, PA.; Division of Hematology, St. Christopher's Hospital for Children, Philadelphia, PA.
Patrick KE; Department of Neurology, Division of Pediatric Neurology, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA.
Iampietro M; Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA.
Apollonsky N; Division of Hematology, St. Christopher's Hospital for Children, Philadelphia, PA.; Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA.
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Źródło :
Journal of pediatric psychology [J Pediatr Psychol] 2021 Jul 20; Vol. 46 (6), pp. 710-718.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell*/drug therapy
Hydroxyurea*/therapeutic use
Child ; Child, Preschool ; Executive Function ; Fetal Hemoglobin ; Hemoglobin, Sickle ; Humans ; Infant ; Infant, Newborn
Czasopismo naukowe
Tytuł :
Experience with combination of hydroxyurea and low-dose thalidomide in transfusion-dependent beta thalassemia patients.
Autorzy :
Bhurani D; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India. .
Kapoor J; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
Yadav N; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
Khushoo V; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
Agrawal N; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
Ahmed R; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
Arora JS; National Thalassemia Welfare Society, Delhi, 110018, India.
Mehta P; Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Sector 5, Rohini, Delhi, 110085, India.
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Źródło :
Annals of hematology [Ann Hematol] 2021 Jun; Vol. 100 (6), pp. 1417-1427. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Antisickling Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Thalidomide/*therapeutic use
beta-Thalassemia/*drug therapy
Adolescent ; Adult ; Antisickling Agents/administration & dosage ; Blood Transfusion ; Child ; Drug Combinations ; Female ; Ferritins/blood ; Follow-Up Studies ; Humans ; Hydroxyurea/administration & dosage ; Immunosuppressive Agents/administration & dosage ; Male ; Retrospective Studies ; Thalidomide/administration & dosage ; Young Adult ; beta-Thalassemia/blood ; beta-Thalassemia/therapy
Czasopismo naukowe
Tytuł :
Hydroxyurea selection for enhancement of homology-directed targeted integration of transgenes in CHO cells.
Autorzy :
Kwak JM; Department of Applied Chemistry and Biological Engineering, Ajou University, Suwon, 16499, Republic of Korea; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
Lee Y; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
Shin SW; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
Lee JS; Department of Applied Chemistry and Biological Engineering, Ajou University, Suwon, 16499, Republic of Korea; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea. Electronic address: .
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Źródło :
New biotechnology [N Biotechnol] 2021 May 25; Vol. 62, pp. 26-31. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Hydroxyurea/*analysis
Animals ; CHO Cells ; Cell Cycle ; Cricetulus ; Gene Editing ; Genetic Engineering ; Hydroxyurea/metabolism
Czasopismo naukowe
Tytuł :
Impact of renal function on hydroxyurea exposure in sickle-cell disease patients.
Autorzy :
Pressiat C; Laboratoire de Pharmacologie, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Rakotoson MG; Centre de référence pour les syndromes drépanocytaires majeurs, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.; Filière MCGRE. DHU A TVB. Institut Mondor de Recherche Biomédicale (IMRB) équipe 2. Laboratoire d'excellence GRex, Université Paris Est-Créteil, Créteil, France.
Habibi A; Centre de référence pour les syndromes drépanocytaires majeurs, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Barau C; Plate-forme de Ressources Biologiques, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Arrouasse R; Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Investigations Cliniques 1430, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Galactéros F; Centre de référence pour les syndromes drépanocytaires majeurs, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Stehlé T; Service de Néphrologie et Transplantation, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.; Inserm U955, équipe 21, IMRB, Université Paris Est-Créteil, Créteil, France.
Audard V; Service de Néphrologie et Transplantation, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.; Inserm U955, équipe 21, IMRB, Université Paris Est-Créteil, Créteil, France.
Hulin A; Laboratoire de Pharmacologie, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.
Bartolucci P; Centre de référence pour les syndromes drépanocytaires majeurs, AP-HP, Hôpitaux Universitaires Henri Mondor, Université Paris Est-Créteil, Créteil, France.; Filière MCGRE. DHU A TVB. Institut Mondor de Recherche Biomédicale (IMRB) équipe 2. Laboratoire d'excellence GRex, Université Paris Est-Créteil, Créteil, France.
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Źródło :
British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 May; Vol. 87 (5), pp. 2274-2285. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anemia, Sickle Cell*/drug therapy
Hydroxyurea*
Antisickling Agents ; Humans ; Kidney/physiology ; Prospective Studies
Czasopismo naukowe
Tytuł :
Hydroyxurea improves cerebral oxygen saturation in children with sickle cell anemia.
Autorzy :
Karkoska K; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Quinn CT; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Niss O; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Pfeiffer A; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Dong M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Vinks AA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
McGann PT; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
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Źródło :
American journal of hematology [Am J Hematol] 2021 May 01; Vol. 96 (5), pp. 538-544. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Comparative Study; Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
Anemia, Sickle Cell/*drug therapy
Antisickling Agents/*therapeutic use
Cerebrovascular Circulation/*drug effects
Hydroxyurea/*therapeutic use
Oximetry/*methods
Adolescent ; Anemia, Sickle Cell/blood ; Anemia, Sickle Cell/physiopathology ; Antisickling Agents/administration & dosage ; Antisickling Agents/pharmacokinetics ; Antisickling Agents/pharmacology ; Child ; Child, Preschool ; Dose-Response Relationship, Drug ; Early Medical Intervention ; Female ; Humans ; Hydroxyurea/administration & dosage ; Hydroxyurea/pharmacokinetics ; Hydroxyurea/pharmacology ; Infant ; Male ; Oximetry/instrumentation ; Oxygen/blood ; Oxyhemoglobins/analysis ; Precision Medicine ; Prospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Comparison of efficacy and safety of thalidomide vs hydroxyurea in patients with Hb E-β thalassemia - a pilot study from a tertiary care Centre of India.
Autorzy :
Jain M; Department of Hematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India.
Chakrabarti P; Department of Hematology, Vivekananda Institute of Medical Sciences, Kolkata, India.
Dolai TK; Department of Hematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India.
Ghosh P; Department of Community Medicine, Deben Mahata Government Medical College, Purulia, West Bengal, India.
Mandal PK; Department of Hematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India.
Baul SN; Department of Hematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India.
De R; Department of Hematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India. Electronic address: .
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Źródło :
Blood cells, molecules & diseases [Blood Cells Mol Dis] 2021 May; Vol. 88, pp. 102544. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antisickling Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Thalidomide/*therapeutic use
beta-Thalassemia/*drug therapy
Adolescent ; Adult ; Antisickling Agents/adverse effects ; Child ; Female ; Hemoglobin E/analysis ; Hemoglobins/analysis ; Humans ; Hydroxyurea/adverse effects ; Immunosuppressive Agents/adverse effects ; India/epidemiology ; Male ; Pilot Projects ; Prospective Studies ; Tertiary Care Centers ; Thalidomide/adverse effects ; Young Adult ; beta-Thalassemia/blood ; beta-Thalassemia/epidemiology
Czasopismo naukowe
Tytuł :
Interferent Effect of Hydroxyurea on Continuous Glucose Monitoring.
Autorzy :
Szmuilowicz ED; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL .
Aleppo G; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
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Źródło :
Diabetes care [Diabetes Care] 2021 May; Vol. 44 (5), pp. e89-e90. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Glucose Self-Monitoring*
Hydroxyurea*/adverse effects
Blood Glucose ; Humans
Raport
Tytuł :
Perception to hydroxyurea therapy in patients with sickle cell disease: Report from 3 centers.
Autorzy :
Korubo KI; Department of Medicine and Community Medicine, College of Health Sciences, Usmanu Danfodiyo University, Renal Centre, Sokoto, Sokoto State, Nigeria.
Onodingene NM; Department of Specialist Hospital, Sokoto, Sokoto State, Nigeria.
Okoye HC; Sir Yahaya Memorial Hospital, Birnin Kebbi, Kebbi State, Nigeria.
Omunakwe HE; Federal Medical Centre, Birnin Kebbi, Kebbi State; Ahmad Sani Yariman Bakura Hospital, Gusau, Zamfara State, Nigeria.
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Źródło :
Annals of African medicine [Ann Afr Med] 2021 Apr-Jun; Vol. 20 (2), pp. 127-131.
Typ publikacji :
Journal Article
MeSH Terms :
Health Knowledge, Attitudes, Practice*
Anemia, Sickle Cell/*drug therapy
Antisickling Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Adolescent ; Adult ; Anemia, Sickle Cell/blood ; Antisickling Agents/administration & dosage ; Child ; Female ; Humans ; Hydroxyurea/administration & dosage ; Male ; Perception ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Hydroxyurea and blood transfusion therapy for Sickle cell disease in South Asia: inconsistent treatment of a neglected disease.
Autorzy :
Darshana T; Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Gangodawila, 10250, Nugegoda, Sri Lanka. .
Rees D; King's College Hospital, London, UK.
Premawardhena A; Department of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
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Źródło :
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2021 Mar 23; Vol. 16 (1), pp. 148. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Anemia, Sickle Cell*/drug therapy
Hydroxyurea*/therapeutic use
Bangladesh ; Blood Transfusion ; Humans ; India ; Neglected Diseases ; Pakistan ; Prospective Studies
Czasopismo naukowe
Tytuł :
Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
Autorzy :
Joseph L; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Biothérapie, Hôpital Universitaire Necker-Enfants Malades, Paris Descartes-Sorbonne, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Jean C; Service de Biologie de la Reproduction, Centre d'Etudes et de la Conservation des Œufs et du Sperme Humains (CECOS), Hôpital Cochin, Université Paris 5, Paris, France.
Manceau S; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Biothérapie, Hôpital Universitaire Necker-Enfants Malades, Paris Descartes-Sorbonne, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.; Laboratory of Excellence (Labex GR-Ex), Paris, France.
Chalas C; Service de Biologie de la Reproduction, Centre d'Etudes et de la Conservation des Œufs et du Sperme Humains (CECOS), Hôpital Cochin, Université Paris 5, Paris, France.
Arnaud C; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Pédiatrie Générale, Hôpital Intercommunal de Créteil, Créteil, France.
Kamdem A; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Pédiatrie Générale, Hôpital Intercommunal de Créteil, Créteil, France.
Pondarré C; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Pédiatrie Générale, Hôpital Intercommunal de Créteil, Créteil, France.
Habibi A; Centre de Référence des Syndromes Drépanocytaires Majeurs, Unité des Maladies Génétiques du Globule Rouge, Hôpital Henri Mondor, AP-HP, Université Paris 12, Créteil, France.
Bernaudin F; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Pédiatrie Générale, Hôpital Intercommunal de Créteil, Créteil, France.
Allali S; Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France.; Laboratoire des Mécanismes Moléculaires des Troubles Hématologiques et Implications Thérapeutiques, Paris Descartes-Sorbonne, Institut Imagine, INSERM Unité 1163, Paris, France.
de Montalembert M; Laboratory of Excellence (Labex GR-Ex), Paris, France.; Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France.
Boutonnat-Faucher B; Service de Pédiatrie Générales et Maladies Infectieuses, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France.
Arlet JB; Laboratory of Excellence (Labex GR-Ex), Paris, France.; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Médecine Interne, Hôpital Européen Georges Pompidou, Université de Paris, Paris, France.
Koehl B; Laboratory of Excellence (Labex GR-Ex), Paris, France.; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service d'Immuno-Hématologie Pédiatrique, Hôpital Robert Debré, Paris, France.
Cavazzana M; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Biothérapie, Hôpital Universitaire Necker-Enfants Malades, Paris Descartes-Sorbonne, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.; Laboratoire de Lymphohématopoïèse Humaine, INSERM Unité Mixte de Recherche (UMR) 1163, Paris, France.
Ribeil JA; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Biothérapie, Hôpital Universitaire Necker-Enfants Malades, Paris Descartes-Sorbonne, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Lionnet F; Centre de Référence des Syndromes Drépanocytaires Majeurs, Service de Médecine Interne, Hôpital Tenon, AP-HP, Paris, France.; Groupe de Recherche Clinique Drépanocytose Recherche à Paris Sorbonne Université, Sorbonne University, Paris, France.
Berthaut I; Service de Biologie de la Reproduction, CECOS, Hôpital Tenon, Université Paris 6, Paris, France; and.
Brousse V; Laboratory of Excellence (Labex GR-Ex), Paris, France.; Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France.; UMR S1134, INSERM, Institut National de la Transfusion Sanguine, Paris, France.
Pokaż więcej
Źródło :
Blood [Blood] 2021 Feb 11; Vol. 137 (6), pp. 826-829.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study
MeSH Terms :
Puberty*
Anemia, Sickle Cell/*drug therapy
Antisickling Agents/*adverse effects
Hydroxyurea/*adverse effects
Infertility, Male/*chemically induced
Spermatogenesis/*drug effects
Spermatozoa/*drug effects
Acute Chest Syndrome/epidemiology ; Acute Chest Syndrome/etiology ; Adolescent ; Age Factors ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/physiopathology ; Anemia, Sickle Cell/therapy ; Antisickling Agents/administration & dosage ; Antisickling Agents/therapeutic use ; Arterial Occlusive Diseases/epidemiology ; Arterial Occlusive Diseases/etiology ; Blood Transfusion ; Child ; Child, Preschool ; Combined Modality Therapy ; Humans ; Hydroxyurea/administration & dosage ; Hydroxyurea/therapeutic use ; Infant ; Male ; Sperm Count ; Sperm Motility/drug effects ; Young Adult
Czasopismo naukowe
Tytuł :
Hydroxyurea does not affect the spermatogonial pool in prepubertal patients with sickle cell disease.
Autorzy :
Gille AS; Département de Génétique, Développement et Cancer. Team From Gametes to Birth, Institut Cochin, INSERM U1016, Paris, France.; UMRE008 Stabilité Génétique, Cellules Souches et Radiations, Laboratoire des Cellules Souches Germinales, Institut de Radiobiologie Cellulaire et Moléculaire, Université de Paris, Université Paris-Saclay, CEA, Fontenay-aux-Roses, France.
Pondarré C; Centre Hospitalier Intercommunal de Créteil, Centre de Référence de la Drépanocytose, Créteil, France.; INSERM Unité 955, Université Paris XII, Créteil, France.
Dalle JH; Faculté de Médecine, Sorbonne Université, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d'Immuno-Hématologie Pédiatrique, Paris, France.
Bernaudin F; Centre Hospitalier Intercommunal de Créteil, Centre de Référence de la Drépanocytose, Créteil, France.
Chalas C; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.
Fahd M; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d'Immuno-Hématologie Pédiatrique, Paris, France.
Jean C; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.; UFR Médecine Paris Centre-Université de Paris, Paris, France.
Lezeau H; Service de Chirurgie Viscérale, Urologie, Traumatologie, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Riou L; UMRE008 Stabilité Génétique, Cellules Souches et Radiations, Laboratoire des Cellules Souches Germinales, Institut de Radiobiologie Cellulaire et Moléculaire, Université de Paris, Université Paris-Saclay, CEA, Fontenay-aux-Roses, France.
Drouineaud V; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.
Paye-Jaouen A; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service de Chirurgie Viscérale et Urologie Pédiatriques, Paris, France.
Kamdem A; Centre Hospitalier Intercommunal de Créteil, Centre de Référence de la Drépanocytose, Créteil, France.
Neven B; UFR Médecine Paris Centre-Université de Paris, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Necker-Enfant Malades, Service d'Immuno-Hématologie et Rhumatologie Pédiatrique, Hôpital Necker-Enfants Malades, Paris, France.
Arnaud C; Centre Hospitalier Intercommunal de Créteil, Centre de Référence de la Drépanocytose, Créteil, France.
Azarnoush S; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d'Immuno-Hématologie Pédiatrique, Paris, France.
Yakouben K; Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d'Immuno-Hématologie Pédiatrique, Paris, France.
Sarnacki S; UFR Médecine Paris Centre-Université de Paris, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Necker-Enfant Malades, Service de Chirurgie Viscérale et Urologique Pédiatriques, Paris, France.
de Montalembert M; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Necker-Enfant Malades, Service de Pédiatrie Générale et Maladies Infectieuses, Centre de Référence des Syndromes Drépanocytaires Majeurs, Labex GR-Ex, Hôpital Necker-Enfants Malades, Paris, France.
Comperat EM; Faculté de Médecine, Sorbonne Université, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Tenon, Service d'Anatomie et Cytologie Pathologiques, Paris, France.
Lenaour G; UFR Médecine Paris Centre-Université de Paris, Paris, France.
Sibony M; UFR Médecine Paris Centre-Université de Paris, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Service de Pathologie, Paris, France; and.
Dhédin N; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Service d'Hématologie, Unité Adolescents Jeunes Adultes, Paris, France.
Vaiman D; Département de Génétique, Développement et Cancer. Team From Gametes to Birth, Institut Cochin, INSERM U1016, Paris, France.
Wolf JP; Département de Génétique, Développement et Cancer. Team From Gametes to Birth, Institut Cochin, INSERM U1016, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.; UFR Médecine Paris Centre-Université de Paris, Paris, France.
Patrat C; Département de Génétique, Développement et Cancer. Team From Gametes to Birth, Institut Cochin, INSERM U1016, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.; UFR Médecine Paris Centre-Université de Paris, Paris, France.
Fouchet P; UMRE008 Stabilité Génétique, Cellules Souches et Radiations, Laboratoire des Cellules Souches Germinales, Institut de Radiobiologie Cellulaire et Moléculaire, Université de Paris, Université Paris-Saclay, CEA, Fontenay-aux-Roses, France.
Poirot C; Faculté de Médecine, Sorbonne Université, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Service d'Hématologie, Unité Adolescents Jeunes Adultes, Paris, France.
Barraud-Lange V; Département de Génétique, Développement et Cancer. Team From Gametes to Birth, Institut Cochin, INSERM U1016, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, CHU Cochin, Laboratoire d'Histologie Embryologie Biologie de la Reproduction CECOS, Paris, France.; UFR Médecine Paris Centre-Université de Paris, Paris, France.
Pokaż więcej
Źródło :
Blood [Blood] 2021 Feb 11; Vol. 137 (6), pp. 856-859.
Typ publikacji :
Comparative Study; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Puberty*
Anemia, Sickle Cell/*drug therapy
Antisickling Agents/*adverse effects
Hydroxyurea/*adverse effects
Spermatogonia/*pathology
Age Factors ; Anemia, Sickle Cell/pathology ; Antisickling Agents/therapeutic use ; Child ; Child, Preschool ; Humans ; Hydroxyurea/pharmacology ; Hydroxyurea/therapeutic use ; Male ; Sample Size ; Spermatogonia/drug effects ; Testis/drug effects ; Testis/pathology
Raport
Tytuł :
Tolerance and humoral immune response to the yellow fever vaccine in sickle cell disease children treated with hydroxyurea: a multicentre prospective study.
Autorzy :
Koehl B; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.; Université de Paris, 48 Bld Serurier, 75019, Paris, France.; INSERM UMRS 1134, BIGR, 6 rue Alexandre Cabanel, 75015, Paris, France.
Aupiais C; INSERM UMRS 1123, ECEVE, 10 avenue de Verdun 75010, Paris, France.; Department of Paediatrics Emergency, Jean Verdier Hospital, APHP, Bondy, France.
Schinckel N; Department of General Paediatrics and Infectious Diseases, Robert Debré Hospital, APHP, Paris, France.
Mornand P; Department of General Paediatrics, Centre for Sickle Cell Disease, Trousseau Hospital, APHP, Sorbonne Université, Paris, France.
Odièvre MH; INSERM UMRS 1134, BIGR, 6 rue Alexandre Cabanel, 75015, Paris, France.; Department of General Paediatrics, Centre for Sickle Cell Disease, Trousseau Hospital, APHP, Sorbonne Université, Paris, France.
Niakate A; Department of General Paediatrics, Centre for Sickle Cell Disease, Trousseau Hospital, APHP, Sorbonne Université, Paris, France.
Brousse V; INSERM UMRS 1134, BIGR, 6 rue Alexandre Cabanel, 75015, Paris, France.; Department of General Paediatrics, Necker-Enfants malades hospital, APHP, 149 rue de Sevres, 75015, Paris, France.
Ithier G; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.
Missud F; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.
Holvoet L; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.
Benkerrou M; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.; INSERM UMRS 1123, ECEVE, 10 avenue de Verdun 75010, Paris, France.
Sorge F; Department of Haematology, Reference Centre of Sickle Cell Disease, Hôpital Robert Debré, APHP, 48 Bd Sérurier, Paris 75019, France.
Faye A; Université de Paris, 48 Bld Serurier, 75019, Paris, France.; INSERM UMRS 1123, ECEVE, 10 avenue de Verdun 75010, Paris, France.; Department of General Paediatrics and Infectious Diseases, Robert Debré Hospital, APHP, Paris, France.
Pokaż więcej
Źródło :
Journal of travel medicine [J Travel Med] 2021 Apr 14; Vol. 28 (3).
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Anemia, Sickle Cell*/drug therapy
Hydroxyurea*/therapeutic use
Immunity, Humoral*
Yellow Fever*/prevention & control
Yellow Fever Vaccine*/immunology
Yellow Fever Vaccine*/standards
Adolescent ; Africa ; Child ; Child, Preschool ; Female ; Humans ; Male ; Prospective Studies ; Vaccination/statistics & numerical data
Czasopismo naukowe
Tytuł :
Blood plasma metabolomics of children and adolescents with sickle cell anaemia treated with hydroxycarbamide: a new tool for uncovering biochemical alterations.
Autorzy :
Ribeiro PR; Metabolomics Research Group, Departamento de Química Orgânica, Instituto de Química, Universidade Federal da Bahia, Salvador, Brazil.
Teixeira RDS; Bahiana School of Medicine and Public Health, Salvador, Bahia, Brasil.
Souza AR; Metabolomics Research Group, Departamento de Química Orgânica, Instituto de Química, Universidade Federal da Bahia, Salvador, Brazil.
Pereira TCS; Metabolomics Research Group, Departamento de Química Orgânica, Instituto de Química, Universidade Federal da Bahia, Salvador, Brazil.
Boffo EF; Metabolomics Research Group, Departamento de Química Orgânica, Instituto de Química, Universidade Federal da Bahia, Salvador, Brazil.
Carosio MGA; Laboratório de Ressonância Magnética Nuclear, Departamento de Química, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Ferreira AG; Laboratório de Ressonância Magnética Nuclear, Departamento de Química, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Oliveira RV; Núcleo de Pesquisa em Cromatografia (Separare), Departamento de Química, Universidade Federal de São Carlos, São Carlos, SP, Brazil.
Rodrigues LEA; Bahiana School of Medicine and Public Health, Salvador, Bahia, Brasil.
Silva JJ; Bahiana School of Medicine and Public Health, Salvador, Bahia, Brasil.
de Souza AJ; Bahiana School of Medicine and Public Health, Salvador, Bahia, Brasil.
Ladeia AMT; Bahiana School of Medicine and Public Health, Salvador, Bahia, Brasil.
Pokaż więcej
Źródło :
British journal of haematology [Br J Haematol] 2021 Mar; Vol. 192 (5), pp. 922-931. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolomics*
Anemia, Sickle Cell/*blood
Antisickling Agents/*therapeutic use
Hydroxyurea/*therapeutic use
Acids/blood ; Acute Chest Syndrome/etiology ; Adolescent ; Amino Acids/blood ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/drug therapy ; Antisickling Agents/pharmacology ; Arterial Occlusive Diseases/etiology ; Biomarkers ; Butyrates/blood ; Child ; Chromatography, High Pressure Liquid ; Creatine/blood ; Creatinine/blood ; Female ; Humans ; Hydroxyurea/pharmacology ; Lysophospholipids/blood ; Male ; Mass Spectrometry ; Membrane Lipids/blood ; Models, Biological ; Nuclear Magnetic Resonance, Biomolecular ; Sphingosine/analogs & derivatives ; Sphingosine/blood
Czasopismo naukowe

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