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Tytuł :
Gene panel diagnostics reveals new pathogenic variants in pulmonary arterial hypertension.
Autorzy :
Eichstaedt CA; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany. .; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany. .
Saßmannshausen Z; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany.
Shaukat M; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Cao D; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Xanthouli P; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Gall H; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany.
Sommer N; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany.
Ghofrani HA; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany.; Department of Medicine, Imperial College, London, UK.; Department of Pneumology, Kerckhoff-Klinik, Bad Nauheim, Germany.
Seyfarth HJ; Department of Pneumology, Medical Clinic II, University Hospital of Leipzig, Leipzig, Germany.
Lerche M; Department of Pneumology, Medical Clinic II, University Hospital of Leipzig, Leipzig, Germany.
Halank M; Medical Clinic I, University Hospital of Dresden, Dresden, Germany.
Kleymann J; Medical Clinic I, University Hospital of Dresden, Dresden, Germany.
Benjamin N; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Harutyunova S; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Egenlauf B; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
Milger K; Department of Internal Medicine V, Ludwig-Maximilian University of Munich; Asklepios Clinic Gauting, Comprehensive Pneumology Centre Munich (CPC), German Center for Lung Research (DZL), Munich, Germany.
Rosenkranz S; Department III of Internal Medicine and Cologne Cardiovascular Research Center (CCRC), Cologne University Heart Center, Cologne, Germany.
Ewert R; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University of Greifswald, Greifswald, Germany.
Klose H; Department of Pneumology, Department of Medicine II, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hoeper MM; Clinic for Pneumology, Hannover Medical School, Hannover and German Centre for Lung Research (DZL), Hannover, Germany.
Olsson KM; Clinic for Pneumology, Hannover Medical School, Hannover and German Centre for Lung Research (DZL), Hannover, Germany.
Lankeit M; Department of Internal Medicine and Cardiology, Campus Virchow Klinikum (CVK), Charité - University Medicine Berlin, Berlin, Germany.; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Lange TJ; Department of Internal Medicine II, Division of Pneumology, University Medical Center Regensburg, Regensburg, Germany.
Hinderhofer K; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany.
Grünig E; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.
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Źródło :
Respiratory research [Respir Res] 2022 Mar 27; Vol. 23 (1), pp. 74. Date of Electronic Publication: 2022 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/diagnosis
Hypertension, Pulmonary*/genetics
Hypertension, Pulmonary*/pathology
Pulmonary Arterial Hypertension*/diagnosis
Pulmonary Arterial Hypertension*/genetics
Activin Receptors, Type II/genetics ; Adenosine Triphosphatases/genetics ; Familial Primary Pulmonary Hypertension/diagnosis ; Familial Primary Pulmonary Hypertension/epidemiology ; Familial Primary Pulmonary Hypertension/genetics ; Genetic Predisposition to Disease/genetics ; Humans ; Membrane Transport Proteins/genetics ; Mutation/genetics ; Protein Serine-Threonine Kinases
Czasopismo naukowe
Tytuł :
Targeted treprostinil delivery inhibits pulmonary arterial remodeling.
Autorzy :
Liu A; Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Li B; Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yang M; Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Shi Y; Department of Geriatrics, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China. Electronic address: .
Su J; Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2022 May 15; Vol. 923, pp. 174700. Date of Electronic Publication: 2022 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*
Pulmonary Arterial Hypertension*/drug therapy
Animals ; Cell Proliferation ; Epoprostenol/analogs & derivatives ; Epoprostenol/metabolism ; Familial Primary Pulmonary Hypertension ; Liposomes/metabolism ; Liposomes/pharmacology ; Liposomes/therapeutic use ; Myocytes, Smooth Muscle ; Pulmonary Artery ; Rats ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry.
Autorzy :
Chang KY; Department of Medicine University of Minnesota Minneapolis MN.
Duval S; Department of Medicine University of Minnesota Minneapolis MN.
Badesch DB; Department of Medicine University of Colorado Denver CO.
Bull TM; Department of Medicine University of Colorado Denver CO.
Chakinala MM; Department of Medicine Washington University St. Louis MO.
De Marco T; Department of Medicine University of California San Francisco San Francisco CA.
Frantz RP; Department of Medicine Mayo Clinic Rochester MN.
Hemnes A; Department of Medicine Vanderbilt University Nashville TN.
Mathai SC; Department of Medicine Johns Hopkins University Baltimore MD.
Rosenzweig EB; Department of Medicine Columbia University New York NY.
Ryan JJ; Department of Medicine University of Utah Salt Lake City UT.
Thenappan T; Department of Medicine University of Minnesota Minneapolis MN.
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Corporate Authors :
PHAR Investigators *
Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2022 May 03; Vol. 11 (9), pp. e024969. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*
Pulmonary Arterial Hypertension*/diagnosis
Adult ; Familial Primary Pulmonary Hypertension ; Female ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Registries ; Survival Rate ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Analysis of necroptosis and its association with pyroptosis in organ damage in experimental pulmonary arterial hypertension.
Autorzy :
Jarabicová I; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Horváth C; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Veľasová E; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Bies Piváčková L; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Vetešková J; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Klimas J; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Křenek P; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
Adameová A; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Comenius University in Bratislava, Bratislava, Slovakia.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2022 May; Vol. 26 (9), pp. 2633-2645. Date of Electronic Publication: 2022 Apr 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypertension, Pulmonary*/metabolism
Pulmonary Arterial Hypertension*
Animals ; DNA-Binding Proteins ; Disease Models, Animal ; Familial Primary Pulmonary Hypertension ; Hypertrophy, Right Ventricular/etiology ; Hypertrophy, Right Ventricular/metabolism ; Monocrotaline/toxicity ; Necroptosis ; Pyroptosis ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Upfront riociguat and ambrisentan combination therapy for newly diagnosed pulmonary arterial hypertension: A prospective open-label trial.
Autorzy :
Weatherald J; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada; Libin Cardiovascular Institute and O'Brien Institute for Public Health, University of Calgary, Calgary, Canada. Electronic address: .
Thakrar MV; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Varughese RA; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada; Department of Medicine, Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada.
Kularatne M; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Liu J; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Harper L; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Kiamanesh O; Libin Cardiovascular Institute and O'Brien Institute for Public Health, University of Calgary, Calgary, Canada; Department of Cardiac Sciences, Division of Cardiology, University of Calgary, Calgary, Canada.
Fine N; Libin Cardiovascular Institute and O'Brien Institute for Public Health, University of Calgary, Calgary, Canada; Department of Cardiac Sciences, Division of Cardiology, University of Calgary, Calgary, Canada.
Orlikow E; Department of Medicine, University of Manitoba, Winnipeg, Canada.
Nwaroh C; Cumming School of Medicine, University of Calgary, Calgary, Canada.
Thornton C; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Swiston J; Department of Medicine, Division of Respiratory Medicine, University of British Columbia, Vancouver, Canada.
Kolkman L; Department of Medicine, Division of Respiratory Medicine, University of British Columbia, Vancouver, Canada.
Brunner NW; Department of Medicine, Division of Cardiology, University of British Columbia, Vancouver, Canada.
Helmersen D; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
Hirani N; Department of Medicine, Division of Respirology, University of Calgary, Calgary, Canada.
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Źródło :
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2022 May; Vol. 41 (5), pp. 563-567. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Hypertension, Pulmonary*/diagnosis
Hypertension, Pulmonary*/drug therapy
Pulmonary Arterial Hypertension*
Aged ; Antihypertensive Agents/therapeutic use ; Endothelin Receptor Antagonists/therapeutic use ; Familial Primary Pulmonary Hypertension/drug therapy ; Female ; Humans ; Male ; Middle Aged ; Phenylpropionates ; Prospective Studies ; Pyrazoles ; Pyridazines ; Pyrimidines ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension.
Autorzy :
Tang Y; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Tan S; Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, China.
Li M; Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, China.
Tang Y; Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, China.
Xu X; Department of Gastroenterology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Hunan Normal University, Changsha, 410005, China.
Zhang Q; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Fu Q; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Tang M; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
He J; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Zhang Y; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Zheng Z; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China.
Peng J; Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, China. .
Zhu T; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, 410011, China. .
Xie W; Department of Pathology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, 518017, China. .
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Źródło :
BMC pulmonary medicine [BMC Pulm Med] 2022 Apr 12; Vol. 22 (1), pp. 142. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/chemically induced
Hypertension, Pulmonary*/drug therapy
Hypertension, Pulmonary*/metabolism
Pulmonary Arterial Hypertension*/chemically induced
Pulmonary Arterial Hypertension*/drug therapy
Animals ; Benzhydryl Compounds ; Disease Models, Animal ; Familial Primary Pulmonary Hypertension/metabolism ; Glucosides ; Humans ; Monocrotaline ; Pulmonary Artery ; Rats ; Sildenafil Citrate/pharmacology ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
The Right Ventricular-Pulmonary Arterial Coupling and Diastolic Function Response to Therapy in Pulmonary Arterial Hypertension.
Autorzy :
Vanderpool RR; Department of Medicine, University of Arizona, Tucson, AZ.
Hunter KS; Department of Bioengineering and Cardiology, UC Denver Medical Campus, Denver, CO.
Insel M; Division of Pulmonary, Critical Care, Sleep, and Allergy Medicine, University of Arizona, Tucson, AZ.
Garcia JGN; Department of Medicine, University of Arizona, Tucson, AZ; Division of Pulmonary, Critical Care, Sleep, and Allergy Medicine, University of Arizona, Tucson, AZ.
Bedrick EJ; BIO5 Institute, Center of Biostatistics and Informatics, University of Arizona, Tucson, AZ.
Tedford RJ; Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC.
Rischard FP; Department of Medicine, University of Arizona, Tucson, AZ; Division of Pulmonary, Critical Care, Sleep, and Allergy Medicine, University of Arizona, Tucson, AZ. Electronic address: .
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Źródło :
Chest [Chest] 2022 Apr; Vol. 161 (4), pp. 1048-1059. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*
Pulmonary Arterial Hypertension*/drug therapy
Ventricular Dysfunction, Right*
Familial Primary Pulmonary Hypertension ; Heart Murmurs ; Humans ; Prospective Studies ; Pulmonary Artery ; Ventricular Function, Right
Czasopismo naukowe
Tytuł :
Novel Mechanisms Targeted by Drug Trials in Pulmonary Arterial Hypertension.
Autorzy :
Condon DF; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University, Stanford, CA.
Agarwal S; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
Chakraborty A; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
Auer N; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
Vazquez R; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
Patel H; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
Zamanian RT; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA.
de Jesus Perez VA; Division of Pulmonary, Allergy, and Critical Care Medicine, Wall Center for Cardiopulmonary Research, Stanford University, Stanford, CA. Electronic address: .
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Źródło :
Chest [Chest] 2022 Apr; Vol. 161 (4), pp. 1060-1072. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heart Failure*/complications
Hypertension, Pulmonary*
Pulmonary Arterial Hypertension*
Familial Primary Pulmonary Hypertension/complications ; Humans ; Quality of Life
Czasopismo naukowe
Tytuł :
Myocardial Edema Provides a Link Between Pulmonary Arterial Hypertension and Pericardial Effusion.
Autorzy :
Stewart RH; Michael E. DeBakey Institute (R.H.S., C.S.C., S.J.A., G.A.L), Texas A&M University, College Station.; Department of Veterinary Physiology and Pharmacology (R.H.S.), Texas A&M University, College Station.
Cox CS Jr; Michael E. DeBakey Institute (R.H.S., C.S.C., S.J.A., G.A.L), Texas A&M University, College Station.; McGovern Medical School at UTHealth, University of Texas Health Science Center at Houston (C.S.C.).
Allen SJ; Michael E. DeBakey Institute (R.H.S., C.S.C., S.J.A., G.A.L), Texas A&M University, College Station.
Laine GA; Michael E. DeBakey Institute (R.H.S., C.S.C., S.J.A., G.A.L), Texas A&M University, College Station.
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Źródło :
Circulation [Circulation] 2022 Mar 15; Vol. 145 (11), pp. 793-795. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/diagnosis
Hypertension, Pulmonary*/etiology
Pericardial Effusion*/diagnostic imaging
Pericardial Effusion*/etiology
Pulmonary Arterial Hypertension*
Edema ; Familial Primary Pulmonary Hypertension ; Humans
Czasopismo naukowe
Tytuł :
Evaluation of pulmonary arterial pressure in patients with connective tissue disease-associated pulmonary arterial hypertension by myocardial perfusion imaging.
Autorzy :
Wang Z; Operating Room, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li J; Department of Neurology, Hankou Hospital, Wuhan, China.
Wang X; Department of Oncology, Zhangqiu Peoples Hospital, Jinan, China.
Liu M; Hospital Infection Management Office, Wuhan No. 1 Hospital, Wuhan, China.
Liao M; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang C; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shang X; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc [Ann Noninvasive Electrocardiol] 2022 Mar; Vol. 27 (2), pp. e12927. Date of Electronic Publication: 2021 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Connective Tissue Diseases*/diagnosis
Connective Tissue Diseases*/diagnostic imaging
Hypertension, Pulmonary*/complications
Hypertension, Pulmonary*/diagnostic imaging
Myocardial Perfusion Imaging*/adverse effects
Pulmonary Arterial Hypertension*/diagnosis
Pulmonary Arterial Hypertension*/diagnostic imaging
Arterial Pressure ; Electrocardiography/adverse effects ; Familial Primary Pulmonary Hypertension/complications ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Efficacy of treat-and-repair strategy for atrial septal defect with pulmonary arterial hypertension.
Autorzy :
Takaya Y; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan .
Akagi T; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Sakamoto I; Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.
Kanazawa H; Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Nakazawa G; Department of Cardiology, Kindai University Faculty of Medicine, Osaka, Japan.
Murakami T; Department of Cardiology, Tokai University Hospital, Isehara, Japan.
Yao A; Division for Health Service Promotion, University of Tokyo, Tokyo, Japan.
Nanasato M; Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Saji M; Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Hirokami M; Department of Cardiology, Teine Keijinkai Hospital, Sapporo, Japan.
Fuku Y; Department of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Hosokawa S; Department of Cardiology, Tokushima Red Cross Hospital, Komatsushima, Japan.
Tada N; Department of Cardiology, Sendai Kousei Hospital, Sendai, Japan.
Matsumoto K; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Imai M; Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.
Nakagawa K; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ito H; Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
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Źródło :
Heart (British Cardiac Society) [Heart] 2022 Mar; Vol. 108 (5), pp. 382-387. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Heart Failure*/etiology
Heart Septal Defects, Atrial*/complications
Heart Septal Defects, Atrial*/therapy
Hypertension, Pulmonary*/diagnosis
Hypertension, Pulmonary*/etiology
Hypertension, Pulmonary*/therapy
Pulmonary Arterial Hypertension*/diagnosis
Pulmonary Arterial Hypertension*/etiology
Pulmonary Arterial Hypertension*/therapy
Cardiac Catheterization/adverse effects ; Familial Primary Pulmonary Hypertension ; Humans ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Efficacy and Safety of Chinese Herbal Medicine Compared With Losartan for Mild Essential Hypertension: A Randomized, Multicenter, Double-Blind, Noninferiority Trial.
Autorzy :
Lai X; Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing, China (X.L., Y.G.).; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (X.L., S.W., G.Z., Y.G.).; Institute for TCM-X, MOE Key Laboratory of Bioinformatics/Bioinformatics Division, BNRIST, Department of Automation, Tsinghua University, Beijing, China. (X.L.).
Dong Z; Department of Traditional Chinese Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China (Z.D., R.C.).
Wu S; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (X.L., S.W., G.Z., Y.G.).
Zhou X; Department of Biostatistics, Beijing International Center for Mathematical Research, Peking University, China (X.Z.).; Department of Biostatistics, School of Public Health, Peking University, Beijing, China (X.Z.).
Zhang G; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (X.L., S.W., G.Z., Y.G.).
Xiong S; Department of Cardiology, People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, China (S.X.).
Wu W; Department of Cardiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China (W.W.).
Cao R; Department of Traditional Chinese Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China (Z.D., R.C.).
Wang X; Department of Cardiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (X.W.).
Hua Q; Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, China (Qi Hua).
Du J; Department of Cardiology of Integrated Chinese and Western Medicine, China-Japan Friendship Hospital, Beijing, China (J.D.).
Fan J; Department of Cardiology, Yantaishan Hospital, Yantai, China (J.F.).
Mao J; Department of Cardiology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China (J.M.).
Jiang W; Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing, China (X.L., Y.G.).; Department of Cardiology, Jiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China (W.J.).
Yuan H; Department of Cardiology, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China (H.Y.).
Chen Y; Department of Cardiology, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China (Y.C.).
Xu Y; Department of Cardiovascular Medicine, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (Y.X.).
Li Z; Department of Cardiology, People's Hospital of Liaoning Province, Shenyang, China (Z.L.).
Zhang J; Department of Cardiology, Chengdu First People's Hospital, Chengdu, China (J.Z.).
Dong G; Department of Hypertension, Jinan Hospital of Traditional Chinese Medicine, Jinan, China (Guiying Dong).
Zhen H; Technical Center for Drug Research and Evaluation, China Association of Traditional Chinese Medicine, Beijing, China (H.Z.).
Ding R; Department of Cardiology, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China (R.D., Z.W.).
Wu Z; Department of Cardiology, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China (R.D., Z.W.).
Gao Y; Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing, China (X.L., Y.G.).; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China (X.L., S.W., G.Z., Y.G.).
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Źródło :
Circulation. Cardiovascular quality and outcomes [Circ Cardiovasc Qual Outcomes] 2022 Mar; Vol. 15 (3), pp. e007923. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Drugs, Chinese Herbal*/adverse effects
Hypertension*/diagnosis
Hypertension*/drug therapy
Antihypertensive Agents/adverse effects ; Blood Pressure ; Double-Blind Method ; Essential Hypertension/chemically induced ; Essential Hypertension/diagnosis ; Essential Hypertension/drug therapy ; Female ; Humans ; Infant ; Losartan/adverse effects ; Male ; Middle Aged ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience.
Autorzy :
Issapour A; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, New York, USA.
Frank B; Division of Pediatric Cardiology, University of Colorado, Children's Hospital Colorado, Aurora, Colorado, USA.
Crook S; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, New York, USA.
Hite MD; Division of Pediatric Cardiology, University of Colorado, Children's Hospital Colorado, Aurora, Colorado, USA.
Dorn ML; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, New York, USA.
Rosenzweig EB; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, New York, USA.
Ivy DD; Division of Pediatric Cardiology, University of Colorado, Children's Hospital Colorado, Aurora, Colorado, USA.
Krishnan US; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, New York, USA.
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Źródło :
Pediatric pulmonology [Pediatr Pulmonol] 2022 Mar; Vol. 57 (3), pp. 724-733. Date of Electronic Publication: 2022 Jan 03.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypertension, Pulmonary*/drug therapy
Phenylpropionates*/adverse effects
Pulmonary Arterial Hypertension*
Pyridazines*/therapeutic use
Adolescent ; Antihypertensive Agents/therapeutic use ; Child ; Child, Preschool ; Drug Therapy, Combination ; Familial Primary Pulmonary Hypertension/drug therapy ; Humans ; Phosphodiesterase 5 Inhibitors/therapeutic use ; Retrospective Studies ; Tadalafil/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension.
Autorzy :
Rhee SJ; Department of Pharmacy, Wonkwang University College of Pharmacy, Iksan, Republic of Korea.
Shin SH; Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Oh J; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea.
Jung YH; Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Choi CW; Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kim HS; Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. .
Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2022 May 05; Vol. 12 (1), pp. 7393. Date of Electronic Publication: 2022 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/drug therapy
Pulmonary Arterial Hypertension*
Body Weight ; Child ; Familial Primary Pulmonary Hypertension ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Sildenafil Citrate/therapeutic use
Czasopismo naukowe
Tytuł :
JAGGED-NOTCH3 signaling in vascular remodeling in pulmonary arterial hypertension.
Autorzy :
Zhang Y; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Hernandez M; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Gower J; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Winicki N; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Morataya X; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Alvarez S; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
Yuan JX; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Shyy J; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Thistlethwaite PA; Division of Cardiothoracic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.
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Źródło :
Science translational medicine [Sci Transl Med] 2022 May 04; Vol. 14 (643), pp. eabl5471. Date of Electronic Publication: 2022 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/metabolism
Pulmonary Arterial Hypertension*
Cell Proliferation ; Cells, Cultured ; Familial Primary Pulmonary Hypertension ; Humans ; Ligands ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Pulmonary Artery/pathology ; Receptor, Notch3/metabolism ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension: The BUMP 2 Randomized Clinical Trial.
Autorzy :
Chappell LC; Department of Women and Children's Health, King's College London, London, United Kingdom.
Tucker KL; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Galal U; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Yu LM; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Campbell H; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Rivero-Arias O; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Allen J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Band R; Department of Psychology, University of Southampton, Southampton, United Kingdom.
Chisholm A; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Crawford C; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Dougall G; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Engonidou L; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Franssen M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Green M; Action on Pre-eclampsia, The Stables, Evesham, Worcestershire, United Kingdom.
Greenfield S; Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Hinton L; The Healthcare Improvement Studies Institute, University of Cambridge, Cambridge, United Kingdom.
Hodgkinson J; Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Lavallee L; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Leeson P; Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
McCourt C; Centre for Maternal and Child Health Research, City, University of London, London, United Kingdom.
Mackillop L; Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom.
Sandall J; Department of Women and Children's Health, King's College London, London, United Kingdom.
Santos M; Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
Tarassenko L; Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
Velardo C; Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
Wilson H; Department of Women and Children's Health, King's College London, London, United Kingdom.
Yardley L; Department of Psychology, University of Southampton, Southampton, United Kingdom.; School of Psychological Science, University of Bristol, Bristol, United Kingdom.
McManus RJ; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
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Corporate Authors :
BUMP 2 Investigators
Źródło :
JAMA [JAMA] 2022 May 03; Vol. 327 (17), pp. 1666-1678.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Blood Pressure Monitoring, Ambulatory*/methods
Hypertension*/diagnosis
Hypertension*/drug therapy
Hypertension*/therapy
Self-Testing*
Adult ; Antihypertensive Agents/therapeutic use ; Blood Pressure ; Chronic Disease ; Female ; Humans ; Hypertension, Pregnancy-Induced/diagnosis ; Hypertension, Pregnancy-Induced/drug therapy ; Hypertension, Pregnancy-Induced/therapy ; Pre-Eclampsia ; Pregnancy ; Telemedicine
Czasopismo naukowe
Tytuł :
The Right Heart Network and Risk Stratification in Pulmonary Arterial Hypertension.
Autorzy :
Haddad F; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; Vera Moulton Wall Center for Pulmonary Disease at Stanford University, Stanford, CA. Electronic address: .
Contrepois K; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; Department of Genetics, Stanford University School of Medicine, Stanford, CA.
Amsallem M; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; Vera Moulton Wall Center for Pulmonary Disease at Stanford University, Stanford, CA.
Denault AY; Department of Anesthesiology and Division of Critical Care, Montreal Heart Institute, University of Montréal, Montréal, QC, Canada.
Bernardo RJ; Vera Moulton Wall Center for Pulmonary Disease at Stanford University, Stanford, CA; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, CA.
Jha A; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA.
Taylor S; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA.
Arthur Ataam J; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA.
Mercier O; Department of Cardiovascular and Thoracic Surgery, Centre Chirurgical Marie-Lannelongue, Paris-South University, Paris, France.
Kuznetsova T; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA; Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Vonk Noordegraaf A; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Zamanian RT; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; Vera Moulton Wall Center for Pulmonary Disease at Stanford University, Stanford, CA; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, CA.
Sweatt AJ; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA; Vera Moulton Wall Center for Pulmonary Disease at Stanford University, Stanford, CA; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, CA.
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Źródło :
Chest [Chest] 2022 May; Vol. 161 (5), pp. 1347-1359. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji :
Journal Article
MeSH Terms :
Pulmonary Arterial Hypertension*
Albumins ; Biomarkers ; Familial Primary Pulmonary Hypertension ; Humans ; Natriuretic Peptide, Brain ; Peptide Fragments ; Prognosis ; Risk Assessment ; Sodium ; Ventricular Remodeling
Czasopismo naukowe
Tytuł :
Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.
Autorzy :
Ruopp NF; Pulmonary, Critical Care, and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts.
Cockrill BA; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Źródło :
JAMA [JAMA] 2022 Apr 12; Vol. 327 (14), pp. 1379-1391.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heart Failure*/drug therapy
Heart Failure*/etiology
Pulmonary Arterial Hypertension*/diagnosis
Pulmonary Arterial Hypertension*/drug therapy
Pulmonary Arterial Hypertension*/etiology
Adult ; Antihypertensive Agents/therapeutic use ; Endothelin Receptor Antagonists/therapeutic use ; Endothelins/therapeutic use ; Guanosine Monophosphate/therapeutic use ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/etiology ; Infant, Newborn ; Nitric Oxide/therapeutic use ; Tadalafil/therapeutic use ; United States
Czasopismo naukowe
Tytuł :
Finding Pulmonary Arterial Hypertension-Switching to Offense to Mitigate Disease Burden.
Autorzy :
Maron BA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Cardiology, Veterans Affairs Boston Healthcare System, West Roxbury, Massachusetts.
Humbert M; Université Paris-Saclay, INSERM, Assistance Publique Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, Le Kremlin Bicêtre, France.
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Źródło :
JAMA cardiology [JAMA Cardiol] 2022 Apr 01; Vol. 7 (4), pp. 369-370.
Typ publikacji :
Journal Article
MeSH Terms :
Hypertension, Pulmonary*/epidemiology
Pulmonary Arterial Hypertension*
Cost of Illness ; Familial Primary Pulmonary Hypertension ; Humans
Czasopismo naukowe
Tytuł :
Food for Thought: The Emerging Role of Intestinal Microbiota in Pulmonary Arterial Hypertension.
Autorzy :
Aldred MA; Department of Medicine Indiana University School of Medicine Indianapolis, Indiana.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2022 Apr; Vol. 66 (4), pp. 361-362.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Gastrointestinal Microbiome*
Hypertension*
Microbiota*
Pulmonary Arterial Hypertension*
Familial Primary Pulmonary Hypertension ; Humans
Opinia redakcyjna

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