Temat: "Hypoglycemic Agents" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Efficacy and Safety of Alogliptin-Pioglitazone Combination for Type 2 Diabetes Mellitus Poorly Controlled with Metformin: A Multicenter, Double-Blind Randomized Trial.
Autorzy:: Park JY; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Lee J; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Choi YH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; MedicalExcellence Inc., Seoul, Korea.
Min KW; Division of Endocrinology and Metabolism, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea.
Han KA; Division of Endocrinology and Metabolism, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea.
Ahn KJ; Division of Endocrinology and Metabolism, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Korea.
Lim S; Division of Endocrinology and Metabolism, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kim YH; Division of Endocrinology and Metabolism, Bundang Jesaeng Hospital, Seongnam, Korea.
Ahn CW; Division of Endocrinology and Metabolism, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Choi KM; Department of Endocrinology, Korea University Guro Hospital, Seoul, Korea.
Yoon KH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Pokaż więcej
Źródło:: Diabetes & metabolism journal [Diabetes Metab J] 2024 Sep; Vol. 48 (5), pp. 915-928. Date of Electronic Publication: 2024 Apr 23.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Multicenter Study
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Uracil*/analogs & derivatives
Uracil*/therapeutic use
Uracil*/adverse effects
Uracil*/administration & dosage
Pioglitazone*/therapeutic use
Pioglitazone*/administration & dosage
Piperidines*/therapeutic use
Piperidines*/adverse effects
Piperidines*/administration & dosage
Metformin*/therapeutic use
Metformin*/administration & dosage
Metformin*/adverse effects
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/adverse effects
Glycated Hemoglobin*/analysis
Drug Therapy, Combination*
Blood Glucose*/drug effects
Blood Glucose*/analysis
Humans ; Male ; Female ; Double-Blind Method ; Middle Aged ; Aged ; Treatment Outcome ; Republic of Korea ; Adult

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Tytuł:: Disparity in Guideline-Based Antidiabetic Drugs Prescribing for Type 2 Diabetes Patients in Primary Healthcare Facilities Across China, 2017-2019.
Autorzy:: Fu M; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.; International Research Center for Medicinal Administration, Peking University, Beijing, China.
Gong Z; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Zhu Y; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Li C; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Li H; International Research Center for Medicinal Administration, Peking University, Beijing, China.
Shi L; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.; International Research Center for Medicinal Administration, Peking University, Beijing, China.
Guan X; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, China.; International Research Center for Medicinal Administration, Peking University, Beijing, China.; Pokaż więcej
Źródło:: Pharmacoepidemiology and drug safety [Pharmacoepidemiol Drug Saf] 2024 Aug; Vol. 33 (8), pp. e5882.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/economics
Primary Health Care*/statistics & numerical data
Practice Patterns, Physicians'*/statistics & numerical data
Practice Patterns, Physicians'*/standards
Practice Guidelines as Topic*
Humans ; China ; Middle Aged ; Male ; Female ; Aged ; Guideline Adherence/statistics & numerical data ; Adult ; Drug Costs ; Metformin/therapeutic use ; Drug Prescriptions/statistics & numerical data

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Tytuł:: Acylated anthocyanins from Dendrobium officinale Kimura & Migo: Structural characteristics, antioxidant and hypoglycemic activities.
Autorzy:: Zhu Z; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Song X; College of Chemical Engineering, Zhejiang University of Technology, 310014 Hangzhou, China.
Huang Y; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Jiang Y; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Yao J; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Li Z; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China.
Huang Z; College of Chemical Engineering, Zhejiang University of Technology, 310014 Hangzhou, China.
Dai F; Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, 310021 Hangzhou, China. Electronic address: .; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2024 Oct 15; Vol. 455, pp. 139952. Date of Electronic Publication: 2024 Jun 03.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/chemistry
Antioxidants*/pharmacology
Dendrobium*/chemistry
Anthocyanins*/chemistry
Anthocyanins*/pharmacology
Hypoglycemic Agents*/chemistry
Hypoglycemic Agents*/pharmacology
Plant Extracts*/chemistry
Plant Extracts*/pharmacology
Chromatography, High Pressure Liquid ; Acylation ; alpha-Amylases/chemistry ; alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/metabolism ; Tandem Mass Spectrometry ; Molecular Structure ; alpha-Glucosidases/chemistry ; alpha-Glucosidases/metabolism ; Humans ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/pharmacology

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Tytuł:: Repurposing antidiabetic drugs for Alzheimer's disease: A review of preclinical and clinical evidence and overcoming challenges.
Autorzy:: Tran J; Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, FL, USA.
Parekh S; Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, FL, USA.
Rockcole J; Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, FL, USA.
Wilson D; Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, FL, USA.
Parmar MS; Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, FL, USA. Electronic address: .; Pokaż więcej
Źródło:: Life sciences [Life Sci] 2024 Oct 15; Vol. 355, pp. 123001. Date of Electronic Publication: 2024 Aug 21.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Alzheimer Disease*/drug therapy
Drug Repositioning*
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/pharmacology
Humans ; Animals ; Neuroprotective Agents/therapeutic use ; Neuroprotective Agents/pharmacology ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Dipeptidyl-Peptidase IV Inhibitors/pharmacology

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Tytuł:: Efficacy and safety of henagliflozin combined with continuous subcutaneous insulin infusion in the treatment of Chinese inpatients with type 2 diabetes mellitus based on a continuous glucose monitoring system: protocol of a multicentre, open-label, inpatient, randomised, controlled trial.
Autorzy:: Wu Y; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Huang Z; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Qin Y; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China .; Pokaż więcej
Źródło:: BMJ open [BMJ Open] 2024 Oct 11; Vol. 14 (10), pp. e084834. Date of Electronic Publication: 2024 Oct 11.
Typ publikacji:: Journal Article; Clinical Trial Protocol; Multicenter Study; Randomized Controlled Trial
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/blood
Insulin*/administration & dosage
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/therapeutic use
Blood Glucose*/drug effects
Blood Glucose*/analysis
Insulin Infusion Systems*
Humans ; China ; Prospective Studies ; Female ; Male ; Middle Aged ; Blood Glucose Self-Monitoring ; Sodium-Glucose Transporter 2 Inhibitors/administration & dosage ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Adult ; Multicenter Studies as Topic ; Aged ; Randomized Controlled Trials as Topic ; Infusions, Subcutaneous ; Glucosides/administration & dosage ; Glucosides/therapeutic use ; Continuous Glucose Monitoring ; East Asian People

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Tytuł:: Design, Synthesis, and Biological Evaluation of Covalently Mucoadhesive Derivatives as Nonsystemic Intestine-Targeted TGR5 Agonists.
Autorzy:: Zhao S; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Wang L; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Huang X; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Xiao Y; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Li M; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Huang X; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Chen X; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Li S; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Xie J; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Liu P; Hebi Key Laboratory of Cardiovascular Diseases, Hebi Key Laboratory of Energy Metabolism, People's Hospital of Hebi, Henan University, Kaifeng 475000, China.
Wang YD; State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Chen WD; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.; Key Laboratory of Receptors-Mediated Gene Regulation and Drug Discovery, School of Basic Medical Science, Inner Mongolia Medical University, Hohhot 010110, China.; Pokaż więcej
Źródło:: Journal of medicinal chemistry [J Med Chem] 2024 Oct 10; Vol. 67 (19), pp. 17701-17712. Date of Electronic Publication: 2024 Sep 25.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, G-Protein-Coupled*/agonists
Receptors, G-Protein-Coupled*/metabolism
Drug Design*
Mice, Inbred C57BL*
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/chemical synthesis
Hypoglycemic Agents*/chemistry
Animals ; Humans ; Caco-2 Cells ; Mice ; Rats ; Male ; Structure-Activity Relationship ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/drug effects ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Rats, Sprague-Dawley

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Tytuł:: The Prevalent New-User Design to Study Drug-Drug Interactions: The Example of Sulfonylureas and Warfarin Interaction on the Risk of Severe Hypoglycemia.
Autorzy:: Wang W; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
Cui Y; Centre for Clinical Epidemiology, Lady Davis Institute, Montreal, Quebec, Canada.
Yu OHY; Centre for Clinical Epidemiology, Lady Davis Institute, Montreal, Quebec, Canada.; Division of Endocrinology and Metabolism, Jewish General Hospital/McGill University, Montreal, Quebec, Canada.
Suissa S; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.; Centre for Clinical Epidemiology, Lady Davis Institute, Montreal, Quebec, Canada.; Department of Medicine, McGill University, Montreal, Quebec, Canada.
Douros A; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.; Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Pokaż więcej
Źródło:: Pharmacoepidemiology and drug safety [Pharmacoepidemiol Drug Saf] 2024 Oct; Vol. 33 (10), pp. e70014.
Typ publikacji:: Journal Article
MeSH Terms:: Warfarin*/adverse effects
Warfarin*/administration & dosage
Sulfonylurea Compounds*/adverse effects
Drug Interactions*
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Anticoagulants*/adverse effects
Anticoagulants*/administration & dosage
Hypoglycemic Agents*/adverse effects
Hypoglycemic Agents*/administration & dosage
Humans ; Female ; Male ; Aged ; Middle Aged ; Pharmacoepidemiology/methods ; United Kingdom/epidemiology ; Research Design ; Databases, Factual ; Aged, 80 and over ; Proportional Hazards Models ; Propensity Score

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Tytuł:: Very-low calorie diet and Semaglutide: Synergy and long-term impact on type 2 diabetes management.
Autorzy:: Zheng Z; Shanghai Eighth People's Hospital, Xu Hui District, Shanghai, China.
Zhao K; Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus, Shanghai, China.
Yang S; Shanghai Eighth People's Hospital, Xu Hui District, Shanghai, China. Electronic address: .; Pokaż więcej
Źródło:: Clinical nutrition (Edinburgh, Scotland) [Clin Nutr] 2024 Oct; Vol. 43 (10), pp. 2350-2351. Date of Electronic Publication: 2024 Sep 06.
Typ publikacji:: Letter
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/diet therapy
Glucagon-Like Peptides*/administration & dosage
Glucagon-Like Peptides*/therapeutic use
Caloric Restriction*/methods
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/therapeutic use
Humans ; Male ; Female ; Middle Aged

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Tytuł:: Response to letter to the editor: An in-depth look at the relationship between anti-diabetic drugs and Alzheimer's disease.
Autorzy:: García-Zamora M; Research Group in Alzheimer Disease, Instituto de Investigación Sanitaria La Fe, Valencia, Spain; Cathedra DeCo MICOF-CEU UCH, University Cardenal Herrera-CEU, Valencia 46115, Spain.
García-Lluch G; Research Group in Alzheimer Disease, Instituto de Investigación Sanitaria La Fe, Valencia, Spain; Cathedra DeCo MICOF-CEU UCH, University Cardenal Herrera-CEU, Valencia 46115, Spain.
Moreno Royo L; Cathedra DeCo MICOF-CEU UCH, University Cardenal Herrera-CEU, Valencia 46115, Spain; Department of Pharmacy, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia 46115, Spain.
Cháfer-Pericás C; Research Group in Alzheimer Disease, Instituto de Investigación Sanitaria La Fe, Valencia, Spain. Electronic address: .
Pardo Albiach J; Embedded Systems and Artificial Intelligence Group, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia 46115, Spain. Electronic address: .; Pokaż więcej
Źródło:: Pharmacological research [Pharmacol Res] 2024 Oct; Vol. 208, pp. 107396. Date of Electronic Publication: 2024 Sep 05.
Typ publikacji:: Letter
MeSH Terms:: Alzheimer Disease*/drug therapy
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/adverse effects
Humans ; Animals ; Diabetes Mellitus, Type 2/drug therapy

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Tytuł:: Synthesis of Pyrazolo[3,4-b]pyridine Derivatives and Their In-Vitro and In-Silico Antidiabetic Activities.
Autorzy:: Rafique I; Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Maqbool T; Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Javed MS; Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan.; Pokaż więcej
Źródło:: Journal of cellular biochemistry [J Cell Biochem] 2024 Oct; Vol. 125 (10), pp. e30646. Date of Electronic Publication: 2024 Sep 06.
Typ publikacji:: Journal Article
MeSH Terms:: Hypoglycemic Agents*/chemical synthesis
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/chemistry
Pyrazoles*/pharmacology
Pyrazoles*/chemistry
Pyrazoles*/chemical synthesis
Pyridines*/chemistry
Pyridines*/chemical synthesis
Pyridines*/pharmacology
Molecular Docking Simulation*
alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/metabolism ; Structure-Activity Relationship ; Animals ; Humans ; Hydrazones/chemistry ; Hydrazones/chemical synthesis ; Hydrazones/pharmacology ; Computer Simulation

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Tytuł:: Carboxymethylation of paramylon derived from Euglena gracilis and its hypoglycemic mechanism in diabetic mice.
Autorzy:: Li H; College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, Jilin, China; State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China.
Wang K; State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China.
Tan M; State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China.
Zhu B; College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, Jilin, China; State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China. Electronic address: .
Wang H; State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Dalian Key Laboratory for Precision Nutrition, Dalian Polytechnic University, Dalian 116034, Liaoning, China. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 4), pp. 134891. Date of Electronic Publication: 2024 Aug 30.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Glucans*/chemistry
Glucans*/pharmacology
Blood Glucose*/metabolism
Euglena gracilis*/chemistry
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/chemistry
Animals ; Mice ; Male ; Methylation ; Liver/metabolism ; Liver/drug effects ; Liver/pathology ; Insulin Resistance ; Lipid Metabolism/drug effects ; Solubility

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Tytuł:: The optimal dose of metformin to control conversion to diabetes in patients with prediabetes: A meta-analysis.
Autorzy:: Yi X; School of nursing, Huzhou University, Huzhou, China.
Pan Y; School of Medicine, Huzhou University, Huzhou, China.
Peng H; School of nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Ren M; School of nursing, Huzhou University, Huzhou, China.
Jia Q; Center for Rehabilitation Medicine, Department of Orthopedics, Department of Nursing, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China. Electronic address: .
Wang B; Huzhou Key Laboratory of Precise Prevention and Control of Major Chronic Diseases, Huzhou University, Huzhou, China. Electronic address: .; Pokaż więcej
Źródło:: Journal of diabetes and its complications [J Diabetes Complications] 2024 Oct; Vol. 38 (10), pp. 108846. Date of Electronic Publication: 2024 Aug 10.
Typ publikacji:: Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:: Diabetes Mellitus, Type 2*/blood
Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Type 2*/prevention & control
Disease Progression*
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/adverse effects
Metformin*/administration & dosage
Metformin*/adverse effects
Prediabetic State*/blood
Prediabetic State*/drug therapy
Prediabetic State*/metabolism
Humans ; Blood Glucose/drug effects ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Dose-Response Relationship, Drug ; Randomized Controlled Trials as Topic

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Tytuł:: Efficacy and safety of insulin glargine 300 U/mL in people with type 2 diabetes in China: The INITIATION study.
Autorzy:: Chen L; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.
Wen B; Department of Endocrinology, People's Hospital of Liaoning Province, Shenyang, China.
Liu H; Department of Endocrinology and Metabolism Diseases, Weifang People's Hospital, First Affiliated Hospital of Weifang Medical University, Weifang, China.
Wu H; Department of Endocrinology, Longgang Central Hospital of Shenzhen, Shenzhen, China.
Duan B; Department of Endocrinology, Heilongjiang Provincial Hospital, Harbin, China.
Shu H; Department of Endocrinology, Zibo Municipal Hospital, Zibo, China.
Zhang Q; Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wu X; Department of Endocrinology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Li M; Sanofi Investment Co., Ltd., Beijing, China.
Han Y; Sanofi Investment Co., Ltd., Beijing, China.
Kang L; Sanofi Investment Co., Ltd., Beijing, China.
Zhang M; Sanofi Investment Co., Ltd., Shanghai, China.; Pokaż więcej
Źródło:: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4571-4582. Date of Electronic Publication: 2024 Jul 29.
Typ publikacji:: Journal Article; Multicenter Study; Clinical Trial, Phase IV
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/blood
Insulin Glargine*/adverse effects
Insulin Glargine*/therapeutic use
Insulin Glargine*/administration & dosage
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/adverse effects
Hypoglycemic Agents*/administration & dosage
Glycated Hemoglobin*/analysis
Glycated Hemoglobin*/metabolism
Glycated Hemoglobin*/drug effects
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Humans ; Male ; Middle Aged ; Female ; China/epidemiology ; Prospective Studies ; Aged ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Treatment Outcome ; Adult ; Glycemic Control/adverse effects

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Tytuł:: Long-term efficacy and safety of enavogliflozin in Korean people with type 2 diabetes: A 52-week extension of a Phase 3 randomized controlled trial.
Autorzy:: Kwak SH; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Han KA; Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, South Korea.
Kim ES; Internal Medicine, Ulsan University Hospital, College of Medicine University of Ulsan, Ulsan, South Korea.
Choi SH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Won JC; Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, South Korea.
Yu JM; Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, South Korea.
Oh S; Department of Internal Medicine, Kyung Hee University Hospital, Seoul, South Korea.
Yoo HJ; Department of Internal Medicine, Korea University Guro Hospital, Seoul, South Korea.
Kim CH; Department of Internal Medicine, Sejong General Hospital, Bucheon, South Korea.
Kim KS; Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea.
Chun S; Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, South Korea.
Kim YH; Department of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, South Korea.
Cho SA; Clinical Development Centre, Daewoong Pharmaceutical Co., Ltd, Seoul, Republic of Korea.
Kim DH; Clinical Development Centre, Daewoong Pharmaceutical Co., Ltd, Seoul, Republic of Korea.
Park KS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea.; Pokaż więcej
Źródło:: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4203-4212. Date of Electronic Publication: 2024 Jul 26.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Glycated Hemoglobin*/analysis
Glycated Hemoglobin*/metabolism
Blood Glucose*/drug effects
Blood Glucose*/metabolism
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/adverse effects
Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Republic of Korea ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Aged ; Treatment Outcome ; Glucosides/adverse effects ; Glucosides/therapeutic use ; Adult ; Hypoglycemia/chemically induced ; Hypoglycemia/epidemiology ; Benzofurans

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Tytuł:: Uncovering the antidiabetic potential of heart-friendly and diuretic bioactive compounds through computer-based drug design.
Autorzy:: Ercin N; Department of Medical Biology, Hamidiye School of Medicine, University of Health Sciences, Istanbul, Turkey. Electronic address: .
Besli N; Department of Medical Biology, Hamidiye School of Medicine, University of Health Sciences, Istanbul, Turkey. Electronic address: .
Kilic U; Department of Medical Biology, Hamidiye School of Medicine, University of Health Sciences, Istanbul, Turkey; Department of Medical Biology, Institute of Health Sciences, University of Health Sciences, Istanbul, Turkey. Electronic address: .; Pokaż więcej
Źródło:: Computational biology and chemistry [Comput Biol Chem] 2024 Oct; Vol. 112, pp. 108180. Date of Electronic Publication: 2024 Aug 18.
Typ publikacji:: Journal Article
MeSH Terms:: Hypoglycemic Agents*/chemistry
Hypoglycemic Agents*/pharmacology
Diuretics*/chemistry
Diuretics*/pharmacology
Drug Design*
Molecular Docking Simulation*
Humans ; Molecular Dynamics Simulation ; Sodium-Glucose Transporter 2/metabolism ; Sodium-Glucose Transporter 2/chemistry ; Sodium-Glucose Transporter 2 Inhibitors/chemistry ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Molecular Structure

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Tytuł:: Metformin effects on plasma zonulin levels correlate with enhanced physical performance in osteoarthritis patients with diabetes.
Autorzy:: Karim A; Basic Medical Sciences, Department of Basic Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates. .; Iron Biology Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates. .
Waheed A; Trauma and Orthopaedics, Department of Orthopaedics, Rehman Medical Institute, Peshawar, Pakistan.
Ahmad F; Basic Medical Sciences, Department of Basic Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates.
Qaisar R; Basic Medical Sciences, Department of Basic Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute of Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Pokaż więcej
Źródło:: Inflammopharmacology [Inflammopharmacology] 2024 Oct; Vol. 32 (5), pp. 3195-3203. Date of Electronic Publication: 2024 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Haptoglobins*/metabolism
Metformin*/pharmacology
Metformin*/therapeutic use
Protein Precursors*/blood
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/therapeutic use
Humans ; Female ; Male ; Aged ; Middle Aged ; Osteoarthritis/drug therapy ; Osteoarthritis/blood ; Physical Functional Performance ; Hand Strength/physiology ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/blood ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Cholera Toxin/blood

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Tytuł:: Effectiveness of switching from dipeptidyl peptidase-4 inhibitor to oral glucagon-like peptide-1 receptor agonist in Japanese participants with type 2 diabetes mellitus: Prospective observational study using propensity score matching.
Autorzy:: Iwamoto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Kimura T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Fushimi Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Iwamoto M; Iwamoto Medical Clinic, Kagawa, Japan.
Tatsumi F; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Sanada J; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Iwamoto Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Katakura Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Shimoda M; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Nakanishi S; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Mune T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Kaku K; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Kaneto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.; Pokaż więcej
Źródło:: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4366-4374. Date of Electronic Publication: 2024 Jul 22.
Typ publikacji:: Journal Article; Observational Study
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/blood
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Dipeptidyl-Peptidase IV Inhibitors*/administration & dosage
Glucagon-Like Peptide-1 Receptor*/agonists
Propensity Score*
Glucagon-Like Peptides*/therapeutic use
Glucagon-Like Peptides*/administration & dosage
Glucagon-Like Peptides*/adverse effects
Glycated Hemoglobin*/analysis
Glycated Hemoglobin*/drug effects
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/administration & dosage
Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Aged ; Japan ; Drug Substitution ; Treatment Outcome ; Blood Glucose/drug effects ; Glycemic Control/methods ; Administration, Oral ; East Asian People

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Tytuł:: Real-world safety profile of once-weekly semaglutide in people with type 2 diabetes: Analysis of pooled data from the SemaglUtide Real-world Evidence (SURE) programme.
Autorzy:: Yale JF; McGill University Health Centre, Montreal, Quebec, Canada.
Major-Pedersen A; Global Safety, Novo Nordisk A/S, Søborg, Denmark.
Catarig AM; Novo Nordisk A/S, Søborg, Denmark.
Jain R; Novo Nordisk Service Centre India Private Ltd., Bengaluru, India.
Menzen M; Gemeinschaftskrankenhaus Bonn, Bonn, Germany.
Holmes P; St. George's Medical Practice, Darlington, UK.; Pokaż więcej
Źródło:: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4429-4440. Date of Electronic Publication: 2024 Aug 08.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Glucagon-Like Peptides*/administration & dosage
Glucagon-Like Peptides*/adverse effects
Glucagon-Like Peptides*/therapeutic use
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/adverse effects
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Humans ; Female ; Male ; Middle Aged ; Aged ; Drug Administration Schedule ; Adult ; Clinical Trials, Phase III as Topic ; Randomized Controlled Trials as Topic

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Tytuł:: Structural characterization, physicochemical properties and hypoglycemic activity of soluble dietary fibers from salt stressed mung bean sprouts.
Autorzy:: Teng C; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Liu J; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Li S; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Ma K; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Xu L; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Feng J; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Chai Z; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Hu X; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Lu Y; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Li Y; Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 4), pp. 134979. Date of Electronic Publication: 2024 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Dietary Fiber*/pharmacology
Vigna*/chemistry
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/chemistry
Salt Stress*/drug effects
Humans ; Hep G2 Cells ; Solubility ; Chemical Phenomena ; Molecular Weight ; Glycoside Hydrolase Inhibitors/pharmacology ; Glycoside Hydrolase Inhibitors/chemistry ; Glucose/metabolism

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Tytuł:: Adherence and persistence among people with type 2 diabetes newly initiating oral semaglutide versus DPP-4is in a US real-world setting.
Autorzy:: Lv L; Novo Nordisk Inc., 800 Scudders Mill Road, Plainsboro, NJ 08536, USA. Electronic address: .
Brady BL; Merative, 100 Phoenix Dr Suite 200, Ann Arbor, MI 48108, USA.
Xie L; Novo Nordisk Inc., 800 Scudders Mill Road, Plainsboro, NJ 08536, USA.
Guevarra M; Novo Nordisk Inc., 800 Scudders Mill Road, Plainsboro, NJ 08536, USA.
Turchin A; Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Pokaż więcej
Źródło:: Primary care diabetes [Prim Care Diabetes] 2024 Oct; Vol. 18 (5), pp. 511-517. Date of Electronic Publication: 2024 Jul 10.
Typ publikacji:: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/blood
Glucagon-Like Peptides*/administration & dosage
Glucagon-Like Peptides*/adverse effects
Glucagon-Like Peptides*/therapeutic use
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Dipeptidyl-Peptidase IV Inhibitors*/administration & dosage
Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Medication Adherence*
Hypoglycemic Agents*/therapeutic use
Hypoglycemic Agents*/administration & dosage
Hypoglycemic Agents*/adverse effects
Glucagon-Like Peptide-1 Receptor*/agonists
Incretins*/therapeutic use
Incretins*/adverse effects
Incretins*/administration & dosage
Humans ; Retrospective Studies ; Male ; Female ; Administration, Oral ; Middle Aged ; Treatment Outcome ; Aged ; Time Factors ; United States ; Databases, Factual ; Biomarkers/blood ; Adult ; Dipeptidyl Peptidase 4

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