Temat: "Hypolipidemic agents" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: High-Dose Fenofibrate Stimulates Multiple Cellular Stress Pathways in the Kidney of Old Rats.
Autorzy:: Wrońska A; Department of Histology, Faculty of Medicine, Medical University of Gdańsk, 80-210 Gdańsk, Poland.
Kieżun J; Department of Human Histology and Embryology, School of Medicine, University of Warmia and Mazury in Olsztyn, 10-082 Olsztyn, Poland.
Kmieć Z; Department of Histology, Faculty of Medicine, Medical University of Gdańsk, 80-210 Gdańsk, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Fenofibrate*/pharmacology
Humans ; Rats ; Animals ; Aged ; Antioxidants/pharmacology ; Kidney/metabolism ; Hypolipidemic Agents/pharmacology ; Gene Expression

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Skocz do pozycji: 2.

Tytuł:: Role of Fenofibrate Use in Dyslipidemia and Related Comorbidities in the Asian Population: A Narrative Review.
Autorzy:: Deerochanawong C; Diabetes and Endocrinology Unit, Department of Medicine, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand.
Kim SG; Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Chang YC; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan.; Pokaż więcej
Źródło:: Diabetes & metabolism journal [Diabetes Metab J] 2024 Mar; Vol. 48 (2), pp. 184-195. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Fenofibrate*/adverse effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Metabolic Syndrome*/drug therapy
Metabolic Syndrome*/epidemiology
Dyslipidemias*/drug therapy
Dyslipidemias*/epidemiology
Hypertriglyceridemia*/drug therapy
Atherosclerosis*/drug therapy
Humans ; Hypolipidemic Agents/adverse effects

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Skocz do pozycji: 3.

Tytuł:: Association of lipid-lowering drugs with osteoarthritis outcomes from a drug-target Mendelian randomization study.
Autorzy:: Ma W; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Hubei Provincial Institute of Traditional Chinese Medicine Wuhan, China.
Chen H; The Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.
Zhang Z; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Hubei Provincial Institute of Traditional Chinese Medicine Wuhan, China.
Xiong Y; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Hubei Provincial Institute of Traditional Chinese Medicine Wuhan, China.; School of Acupuncture-Moxibustion and Orthopedics, Hubei University of Chinese Medicine, Wuhan, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 28; Vol. 19 (2), pp. e0293960. Date of Electronic Publication: 2024 Feb 28 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Osteoarthritis, Knee*/drug therapy
Osteoarthritis, Knee*/genetics
Humans ; Proprotein Convertase 9 ; Cholesterol, LDL ; Mendelian Randomization Analysis ; Hypolipidemic Agents/adverse effects ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 4.

Tytuł:: An improved method for estimating low LDL-C based on the enhanced Sampson-NIH equation.
Autorzy:: Coverdell TC; Clinical Center, Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, USA.
Sampson M; Clinical Center, Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, USA.
Zubirán R; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Wolska A; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Donato LJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Meeusen JW; Cardiovascular Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.
Jaffe AS; Division of Clinical Core Laboratory Services, Mayo Clinic, Rochester, MN, USA.
Remaley AT; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2024 Feb 08; Vol. 23 (1), pp. 43. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Proprotein Convertase 9*/genetics
Cardiovascular Diseases*/drug therapy
Humans ; Cholesterol, LDL ; Hypolipidemic Agents ; Triglycerides

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Skocz do pozycji: 5.

Tytuł:: Fibrates Affect Levels of Phosphorylated p38 in Intestinal Cells in a Differentiation-Dependent Manner.
Autorzy:: Cizkova K; Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, 779 00 Olomouc, Czech Republic.
Tauber Z; Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, 779 00 Olomouc, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 22; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 22.
Typ publikacji:: Journal Article
MeSH Terms:: PPAR alpha*/metabolism
Hypolipidemic Agents*/pharmacology
Humans ; Fibric Acids/pharmacology ; Caco-2 Cells ; Cell Differentiation

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Skocz do pozycji: 6.

Tytuł:: No change in small low-density lipoprotein cholesterol levels with pemafibrate might explain the negative results of the PROMINENT trial.
Autorzy:: Hirano T; Diabetes Center, Ebina General Hospital, Kanagawa, Japan.; Pokaż więcej
Źródło:: Journal of diabetes investigation [J Diabetes Investig] 2023 Apr; Vol. 14 (4), pp. 630-631. Date of Electronic Publication: 2023 Jan 27.
Typ publikacji:: Letter; Comment
MeSH Terms:: Negative Results*
Hypolipidemic Agents*
Humans ; Cholesterol ; Lipoproteins, LDL ; Cholesterol, HDL ; Triglycerides

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Skocz do pozycji: 7.

Tytuł:: Exploring the hypolipidemic effects of bergenin from Saxifraga melanocentra Franch: mechanistic insights and potential for hyperlipidemia treatment.
Autorzy:: Zhang L; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810001, P. R. China.
Tong Y; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810001, P. R. China.; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai, 264005, P. R. China.
Fang Y; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810001, P. R. China.; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai, 264005, P. R. China.
Pei J; Qinba State Key Laboratory of biological resources and ecological environment, Province Key Laboratory of Bioresources, College of Bioscience and bioengineering, QinLing-Bashan Mountains Bioresources Comprehensive Development C. I. C, Shaanxi University of Technology, Hanzhong, 723001, Shaanxi, China.
Wang Q; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810001, P. R. China. .
Li G; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai, 264005, P. R. China. ligang_.; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2023 Nov 24; Vol. 22 (1), pp. 203. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:: Journal Article
MeSH Terms:: Hyperlipidemias*/drug therapy
Hyperlipidemias*/genetics
Saxifragaceae*
Animals ; Interleukin-4 ; Molecular Docking Simulation ; Zebrafish ; Triglycerides ; Cholesterol, LDL ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use

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Skocz do pozycji: 8.

Tytuł:: Bile Acid Diarrhea: From Molecular Mechanisms to Clinical Diagnosis and Treatment in the Era of Precision Medicine.
Autorzy:: Yang D; Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Lyu C; State Key Laboratory of Complex Severe and Rare Diseases, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
He K; State Key Laboratory of Complex Severe and Rare Diseases, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Pang K; Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Guo Z; Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Wu D; State Key Laboratory of Complex Severe and Rare Diseases, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Bile Acids and Salts*
Precision Medicine*/adverse effects
Humans ; Diarrhea/diagnosis ; Diarrhea/drug therapy ; Fibroblast Growth Factors/metabolism ; Hypolipidemic Agents/therapeutic use

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Skocz do pozycji: 9.

Tytuł:: Safety and efficacy of bempedoic acid among patients with statin intolerance and those without: A meta-analysis and a systematic randomized controlled trial review.
Autorzy:: Li Y; Department of Cardiology, No 1 Hospital Of Baoding, Baoding, Hebei, China.
Gao H; Department of Cardiology, No 1 Hospital Of Baoding, Baoding, Hebei, China.
Zhao J; Department of Cardiology, No 1 Hospital Of Baoding, Baoding, Hebei, China.
Ma L; Department of Cardiology, No 1 Hospital Of Baoding, Baoding, Hebei, China.
Hu D; Department of Cardiology, No 1 Hospital Of Baoding, Baoding, Hebei, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 26; Vol. 19 (1), pp. e0297854. Date of Electronic Publication: 2024 Jan 26 (Print Publication: 2024).
Typ publikacji:: Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects
Hypercholesterolemia*/drug therapy
Hypercholesterolemia*/chemically induced
Humans ; Dicarboxylic Acids/adverse effects ; Fatty Acids/adverse effects ; Hypolipidemic Agents/therapeutic use ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 10.

Tytuł:: Association of high LDL concentrations with erectile dysfunction from a Mendelian randomization study.
Autorzy:: Zhu Q; Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Tan Y; Department of Ophthalmology, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Yuelu District, Changsha, 410013, Hunan, China.
Zou X; The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Lu L; Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Dec 14; Vol. 13 (1), pp. 22252. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:: Journal Article
MeSH Terms:: Erectile Dysfunction*/genetics
Male ; Humans ; Mendelian Randomization Analysis ; Hypolipidemic Agents ; Lipid Metabolism ; Lipids ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 11.

Tytuł:: Lipid-Lowering Drug Gemfibrozil Protects Mice from Tay-Sachs Disease via Peroxisome Proliferator-Activated Receptor α.
Autorzy:: Raha S; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Dutta D; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Paidi RK; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Pahan K; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, 820 South Damen Avenue, Chicago, IL 60612, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Dec 08; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:: Tay-Sachs Disease*/drug therapy
Humans ; Animals ; Mice ; PPAR alpha/therapeutic use ; Gemfibrozil/pharmacology ; Gemfibrozil/therapeutic use ; beta-N-Acetylhexosaminidases ; Hypolipidemic Agents/therapeutic use ; Glycoconjugates

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Skocz do pozycji: 12.

Tytuł:: The Association between Single Nucleotide Polymorphisms, including miR-499a Genetic Variants, and Dyslipidemia in Subjects Treated with Pharmacological or Phytochemical Lipid-Lowering Agents.
Autorzy:: Giuliani A; Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.
Montesanto A; Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Matacchione G; Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.
Graciotti L; Department of Excellence SBSP-Biomedical Sciences and Public Health, Università Politecnica delle Marche, 60126 Ancona, Italy.
Ramini D; Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, 60121 Ancona, Italy.
Protic O; Cardiology Unit, IRCCS INRCA, 60127 Ancona, Italy.
Galeazzi R; Clinical Laboratory and Molecular Diagnostic, IRCCS INRCA, 60127 Ancona, Italy.
Antonicelli R; Cardiology Unit, IRCCS INRCA, 60127 Ancona, Italy.
Tortato E; Metabolic Diseases and Diabetology Department, IRCCS INRCA, 60127 Ancona, Italy.
Bonfigli AR; Scientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Sabbatinelli J; Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.; Laboratory Medicine Unit, Azienda Ospedaliero Universitaria Ospedali Riuniti, 60126 Ancona, Italy.
Olivieri F; Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.; Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, 60121 Ancona, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 May 17; Vol. 23 (10). Date of Electronic Publication: 2022 May 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cardiovascular Diseases*/drug therapy
Cardiovascular Diseases*/genetics
Cardiovascular Diseases*/metabolism
Dyslipidemias*/drug therapy
Dyslipidemias*/genetics
Dyslipidemias*/metabolism
Hypolipidemic Agents*/pharmacology
MicroRNAs*/genetics
Aryldialkylphosphatase/genetics ; Humans ; Lipid Metabolism/drug effects ; Phytochemicals/pharmacology ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 13.

Tytuł:: An Insight into Antihyperlipidemic Effects of Polysaccharides from Natural Resources.
Autorzy:: Jing YS; College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China.
Ma YF; College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China.
Pan FB; Huachuang Institute of Areca Research-Hainan, Haikou 570125, China.
Li MS; College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China.
Zheng YG; College of Pharmacy, Hebei University of Chinese Medicine, 3 Xingyuan Road, Shijiazhuang 050200, China.
Wu LF; College of Pharmacy, Hebei University of Chinese Medicine, 3 Xingyuan Road, Shijiazhuang 050200, China.
Zhang DS; College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Mar 15; Vol. 27 (6). Date of Electronic Publication: 2022 Mar 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hyperlipidemias*/drug therapy
Hypolipidemic Agents*/chemistry
Hypolipidemic Agents*/pharmacology
Hypolipidemic Agents*/therapeutic use
Humans ; Natural Resources ; Polysaccharides/chemistry ; Polysaccharides/pharmacology ; Polysaccharides/therapeutic use

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Skocz do pozycji: 14.

Tytuł:: Potential Effect of Baobab's Polyphenols as Antihyperlipidemic Agents: In Silico Study.
Autorzy:: Alameen AA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alothman MR; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Al Wahibi MS; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Abdullah EM; Department of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ali R; Department of Drug and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Abdalla M; Department of Medicine, Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.
Fattiny SZA; Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.
Elsayim R; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 17; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Adansonia*
Catechin*
Polyphenols/pharmacology ; Chlorogenic Acid ; Ligands ; Molecular Docking Simulation ; Quercetin ; Hypolipidemic Agents/pharmacology ; Simvastatin/pharmacology ; Lipase ; Coenzyme A ; Oxidoreductases

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Skocz do pozycji: 15.

Tytuł:: Antioxidant and antihyperlipidemic activities of catechol derivatives and biflavonoid isolated from Semecarpus anacardium seeds.
Autorzy:: Sundaram R; Department of Medical Biochemistry, Dr. ALMPG, IBMS, University of Madras, Taramani Campus, Chennai, India.; Central Research Laboratory Meenakshi Ammal Dental College, Meenakshi Academy of Higher Education and Research, Chennai, India.
Muthu K; Department of Chemistry, Manonmaniam Sundaranar University, Tirunelveli, India.
Shanthi P; Department of Pathology, Dr. ALMPG, IBMS, University of Madras, Chennai, India.
Sachdanandam P; Department of Medical Biochemistry, Dr. ALMPG, IBMS, University of Madras, Taramani Campus, Chennai, India.; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2022 Feb; Vol. 32 (2), pp. 123-131. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/pharmacology
Biflavonoids*/pharmacology
Catechols*/pharmacology
Hypolipidemic Agents*/therapeutic use
Semecarpus*/chemistry
Animals ; Hypercholesterolemia/drug therapy ; Plant Extracts/therapeutic use ; Rats ; Seeds/chemistry

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Skocz do pozycji: 16.

Tytuł:: PCSK9 as a Target for Development of a New Generation of Hypolipidemic Drugs.
Autorzy:: Kuzmich N; Laboratory of Drug Safety, Smorodintsev Research Institute of Influenza, WHO National Influenza Centre of Russia, 15/17 Professor Popov Street, 197376 Saint-Petersburg, Russia.; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Andresyuk E; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Porozov Y; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.; Department of Computational Biology, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Tarasov V; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Samsonov M; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Preferanskaya N; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Veselov V; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.
Alyautdin R; Department of Pharmacology, I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya Street, 119991 Moscow, Russia.; Scientific Centre for Expertise of Medicinal Application Products, 8 Petrovski Boulevard, 127051 Moscow, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 10; Vol. 27 (2). Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Proprotein Convertase 9*/chemistry
Proprotein Convertase 9*/physiology
Hypolipidemic Agents/*pharmacology
Receptors, LDL/*metabolism
Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Hypolipidemic Agents/chemistry ; Molecular Targeted Therapy

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Skocz do pozycji: 17.

Tytuł:: Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo.
Autorzy:: Folahan JT; School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, 71209, USA.; Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, University of Ilorin, Ilorin, Kwara-State, Nigeria.
Olorundare OE; Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, University of Ilorin, Ilorin, Kwara-State, Nigeria. .
Ajayi AM; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Oyo-State, Nigeria.
Oyewopo AO; Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Kwara- State, Nigeria.
Soyemi SS; Department of Pathology and Forensic Medicine, Faculty of Basic Clinical Sciences, Lagos State University College of Medicine, Ikeja, Nigeria.
Adeneye AA; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Clinical Sciences, Lagos State University College of Medicine, Ikeja, Nigeria.
Okoye II; Department of Oral Pathology and Medicine, Faculty of Dentistry, Lagos State University College of Medicine, Ikeja, Nigeria.
Afolabi SO; Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, University of Ilorin, Ilorin, Kwara-State, Nigeria.
Njan AA; Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, University of Ilorin, Ilorin, Kwara-State, Nigeria.; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2023 Jul 26; Vol. 22 (1), pp. 107. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:: Journal Article
MeSH Terms:: Estradiol*/pharmacology
Atherosclerosis*/drug therapy
Rats ; Animals ; Female ; Humans ; Nitric Oxide ; Postmenopause ; Tumor Necrosis Factor-alpha ; Lipids ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use ; Diet ; Atorvastatin ; Cholesterol ; Estrogens ; Inflammation/drug therapy ; Ovariectomy

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Skocz do pozycji: 18.

Tytuł:: Comparison of the Efficiency of Lepidium sativum , Ficus carica , and Punica granatum Methanolic Extracts in Relieving Hyperglycemia and Hyperlipidemia of Streptozotocin-Induced Diabetic Rats.
Autorzy:: Ramadan S; Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.
Hegab AM; Developmental Pharmacology Department, The National Organization for Drug Control and Research (NODCAR), Egypt.
Al-Awthan YS; Department of Biology, Faculty of Science, University of Tabuk, 71491 Tabuk, Saudi Arabia.
Al-Duais MA; Biochemistry Department, Faculty of Science, University of Tabuk, 71491 Tabuk, Saudi Arabia.
Tayel AA; Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Egypt.
Al-Saman MA; Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2021 Dec 21; Vol. 2021, pp. 6018835. Date of Electronic Publication: 2021 Dec 21 (Print Publication: 2021).
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Ficus*/chemistry
Lepidium sativum*/chemistry
Pomegranate*/chemistry
Blood Glucose/*drug effects
Diabetes Mellitus, Experimental/*drug therapy
Hyperlipidemias/*drug therapy
Hypoglycemic Agents/*pharmacology
Hypolipidemic Agents/*pharmacology
Lipids/*blood
Plant Extracts/*pharmacology
Animals ; Biomarkers/blood ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/chemically induced ; Glycated Hemoglobin/metabolism ; Hyperlipidemias/blood ; Hyperlipidemias/chemically induced ; Hypoglycemic Agents/isolation & purification ; Hypolipidemic Agents/isolation & purification ; Male ; Plant Extracts/isolation & purification ; Rats ; Streptozocin

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Skocz do pozycji: 19.

Tytuł:: Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients with familial partial lipodystrophy (FPLD): results of a proof-of-concept study.
Autorzy:: Foss-Freitas MC; Division of Metabolism, Endocrinology & Diabetes and Caswell Diabetes Institute, University of Michigan, MI, Ann Arbor, USA.; Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, Michigan Medicine, University of Michigan, Caswell Diabetes Institute, 2800 Plymouth Road, North Campus Research Complex, 25-3696, MI, 48109-2800, Ann Arbor, USA.
Akinci B; Division of Metabolism, Endocrinology & Diabetes and Caswell Diabetes Institute, University of Michigan, MI, Ann Arbor, USA.; Dokuz Eylul University, İzmir, Turkey.; Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, Michigan Medicine, University of Michigan, Caswell Diabetes Institute, 2800 Plymouth Road, North Campus Research Complex, 25-3696, MI, 48109-2800, Ann Arbor, USA.
Neidert A; Division of Metabolism, Endocrinology & Diabetes and Caswell Diabetes Institute, University of Michigan, MI, Ann Arbor, USA.; Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, Michigan Medicine, University of Michigan, Caswell Diabetes Institute, 2800 Plymouth Road, North Campus Research Complex, 25-3696, MI, 48109-2800, Ann Arbor, USA.
Bartlett VJ; Akcea Therapeutics, Inc, MA, Boston, USA.
Hurh E; Akcea Therapeutics, Inc, MA, Boston, USA.
Karwatowska-Prokopczuk E; Akcea Therapeutics, Inc, MA, Boston, USA.
Oral EA; Division of Metabolism, Endocrinology & Diabetes and Caswell Diabetes Institute, University of Michigan, MI, Ann Arbor, USA. .; Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, Michigan Medicine, University of Michigan, Caswell Diabetes Institute, 2800 Plymouth Road, North Campus Research Complex, 25-3696, MI, 48109-2800, Ann Arbor, USA. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2021 Dec 05; Vol. 20 (1), pp. 174. Date of Electronic Publication: 2021 Dec 05.
Typ publikacji:: Clinical Trial, Phase II; Journal Article
MeSH Terms:: Angiopoietin-Like Protein 3*/metabolism
Hypolipidemic Agents*/therapeutic use
Lipodystrophy, Familial Partial*/drug therapy
Adult ; Female ; Humans ; Male ; Middle Aged ; Lipoproteins, LDL/blood ; Proof of Concept Study ; Triglycerides/blood

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Tytuł:: Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways.
Autorzy:: Irshad N; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Khan AU; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Shah FA; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Nadeem H; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Ashraf Z; Department of Chemistry, Allama Iqbal Open University, Islamabad, Pakistan.
Tipu MK; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Li S; State Key Laboratory of Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen, China.; Pokaż więcej
Źródło:: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2021 Dec; Vol. 35 (6), pp. 1119-1132. Date of Electronic Publication: 2021 May 02.
Typ publikacji:: Journal Article
MeSH Terms:: Antihypertensive Agents*
Hypolipidemic Agents*/pharmacology
Animals ; Antioxidants ; Liver ; Pyrimidines/pharmacology ; Rats ; Triglycerides

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