Temat: "Hypoxia" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Myricetin attenuates hypoxia-induced inflammation in human adipocytes.
Autorzy:: Geiger K; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria. .; Medical Central Laboratories, Feldkirch, Austria. .
Muendlein A; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Leiherer A; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Medical Central Laboratories, Feldkirch, Austria.; Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.
Gaenger S; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Brandtner EM; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Wabitsch M; Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Fraunberger P; Medical Central Laboratories, Feldkirch, Austria.
Drexel H; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.; Vorarlberger Landeskrankenhausbetriebsgesellschaft, Academic Teaching Hospital Feldkirch, Feldkirch, Austria.; Drexel University College of Medicine, Philadelphia, PA, USA.
Heinzle C; Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.; Medical Central Laboratories, Feldkirch, Austria.; Pokaż więcej
Źródło:: Molecular biology reports [Mol Biol Rep] 2023 Dec; Vol. 50 (12), pp. 9833-9843. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:: Journal Article
MeSH Terms:: Adipocytes*/metabolism
Hypoxia*/complications
Hypoxia*/metabolism
Humans ; Cell Hypoxia ; Adipokines/metabolism ; Flavonoids/pharmacology ; Flavonoids/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Anti-Inflammatory Agents/pharmacology ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
SCR Disease Name:: Simpson-Golabi-Behmel syndrome

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Skocz do pozycji: 2.

Tytuł:: A simplified protocol to induce hypoxia in a standard incubator: A focus on retinal cells.
Autorzy:: Kaur B; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: .
Miglioranza Scavuzzi B; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: .
F Abcouwer S; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: .
N Zacks D; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: .; Pokaż więcej
Źródło:: Experimental eye research [Exp Eye Res] 2023 Nov; Vol. 236, pp. 109653. Date of Electronic Publication: 2023 Oct 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Hypoxia*
Cobalt*/toxicity
Humans ; Cell Line ; Oxygen ; Hypoxia-Inducible Factor 1, alpha Subunit ; Cell Hypoxia/physiology

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Skocz do pozycji: 3.

Tytuł:: Effects of hypoxia in cardiac metabolic remodeling and heart failure.
Autorzy:: Jiang M; Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, Shanghai, China.
Fan X; Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, Shanghai, China.
Wang Y; Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, Shanghai, China. Electronic address: .
Sun X; Department of Cardiothoracic Surgery, Huashan Hospital of Fudan University, Shanghai, China. Electronic address: .; Pokaż więcej
Źródło:: Experimental cell research [Exp Cell Res] 2023 Nov 01; Vol. 432 (1), pp. 113763. Date of Electronic Publication: 2023 Sep 17.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypoxia*/metabolism
Heart Failure*/metabolism
Humans ; Adult ; Myocytes, Cardiac/metabolism ; Cell Respiration ; Oxygen/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Cell Hypoxia

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Skocz do pozycji: 4.

Tytuł:: CDCA8 promotes bladder cancer survival by stabilizing HIF1α expression under hypoxia.
Autorzy:: Zhou Q; Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Huang W; Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiong J; Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, China.; Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Guo B; Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, China.
Wang X; Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. .
Guo J; Department of Urology, First Affiliated Hospital of Nanchang University, Nanchang, China. .; Pokaż więcej
Źródło:: Cell death & disease [Cell Death Dis] 2023 Oct 09; Vol. 14 (10), pp. 658. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Urinary Bladder Neoplasms*/genetics
Humans ; Cell Hypoxia ; Cell Line ; Cell Line, Tumor ; Hypoxia ; Oxygen ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism

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Skocz do pozycji: 5.

Tytuł:: Hypoxia Modulates Cellular Endocytic Pathways and Organelles with Enhanced Cell Migration and 3D Cell Invasion.
Autorzy:: A Naveena H; Biological Engineering Discipline, Indian Institute of Technology Gandhinagar, Palaj Gandhinagar, 382355, Gujarat, India.
Bhatia D; Biological Engineering Discipline, Indian Institute of Technology Gandhinagar, Palaj Gandhinagar, 382355, Gujarat, India.; Pokaż więcej
Źródło:: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Nov 02; Vol. 24 (21), pp. e202300506. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypoxia*/complications
Hypoxia*/metabolism
Hypoxia*/pathology
Mitochondria*/metabolism
Humans ; Cell Movement ; Cell Hypoxia ; Cell Proliferation ; Clathrin/metabolism ; Clathrin/pharmacology

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Skocz do pozycji: 6.

Tytuł:: Pharmacological modulation of HIF-1 in the treatment of neuropsychiatric disorders.
Autorzy:: Sharma D; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India.
Khan H; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India.
Kumar A; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India.
Grewal AK; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India.
Dua K; Discipline of Pharmacy, Graduate School of Health, The University of Technology Sydney, Sydney, NSW, 2007, Australia.; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
Singh TG; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India. .; Pokaż więcej
Źródło:: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2023 Dec; Vol. 130 (12), pp. 1523-1535. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hypoxia*/drug therapy
Hypoxia*/genetics
Hypoxia*/metabolism
Oxygen*/metabolism
Humans ; Hypoxia-Inducible Factor 1

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Skocz do pozycji: 7.

Tytuł:: Neuroprotective Action of Tacrolimus before and after Onset of Neonatal Hypoxic-Ischaemic Brain Injury in Rats.
Autorzy:: Smith MJ; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia.
Penny T; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
Pham Y; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
Sutherland AE; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
Jenkin G; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia.
Fahey MC; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Paediatrics, Monash University, Clayton, VIC 3168, Australia.
Paton MCB; Cerebral Palsy Alliance Research Institute, Speciality of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2050, Australia.
Finch-Edmondson M; Cerebral Palsy Alliance Research Institute, Speciality of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2050, Australia.
Miller SL; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia.
McDonald CA; The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Nov 20; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:: Journal Article
MeSH Terms:: Hypoxia-Ischemia, Brain*/drug therapy
Hypoxia-Ischemia, Brain*/metabolism
Brain Injuries*
Animals ; Rats ; Animals, Newborn ; Tacrolimus/pharmacology ; Tacrolimus/therapeutic use ; Neuroinflammatory Diseases ; Hypoxia ; Brain Infarction

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Skocz do pozycji: 8.

Tytuł:: Hypoxia stabilizes SETDB1 to maintain genome stability.
Autorzy:: Park S; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Cho JH; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Kim JH; Korea Bioinformation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Park M; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.
Park S; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Kim SY; Korea Bioinformation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.
Kim SK; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.
Kim K; R&D Center, PharmAbcine Inc., Daejeon 34047, Republic of Korea.
Park SG; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.
Park BC; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Moon JH; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Lee G; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.
Kim S; Drug Discovery Center, LG Chem Ltd., Seoul 07796, Republic of Korea.
Kim JA; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.
Kim JH; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon 34113, Republic of Korea.; Graduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 34134, Republic of Korea.; Pokaż więcej
Źródło:: Nucleic acids research [Nucleic Acids Res] 2023 Nov 10; Vol. 51 (20), pp. 11178-11196.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genomic Instability*
Histone-Lysine N-Methyltransferase*/metabolism
Hypoxia*/genetics
Hypoxia*/metabolism
Humans ; Genes, Tumor Suppressor ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Oxygen/metabolism ; Ubiquitin-Protein Ligases/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/metabolism

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Skocz do pozycji: 9.

Tytuł:: N-Acetyl Serotonin Provides Neuroprotective Effects by Inhibiting Ferroptosis in the Neonatal Rat Hippocampus Following Hypoxic Brain Injury.
Autorzy:: Yang X; Department of Anesthesiology, Qilu Hospital of Shangdong University, 107 Wenhua Xi Road, Jinan, 250012, Shandong, China.; Department of Anesthesiology, School of Medicine, Shandong University, 44 Wenhua Xi Road, Jinan, 250012, Shandong, China.
Yang Y; Department of Anesthesiology, Qilu Hospital of Shangdong University, 107 Wenhua Xi Road, Jinan, 250012, Shandong, China.
Gao F; Biomedical Isotope Research Center, School of Basic Medical Sciences, Shandong University, Jinan, 250012, Shandong, China.
Lu K; Department of Anesthesiology, School of Medicine, Shandong University, 44 Wenhua Xi Road, Jinan, 250012, Shandong, China.
Wang C; Department of Anesthesiology, Qilu Hospital of Shangdong University, 107 Wenhua Xi Road, Jinan, 250012, Shandong, China. .; Pokaż więcej
Źródło:: Molecular neurobiology [Mol Neurobiol] 2023 Nov; Vol. 60 (11), pp. 6307-6315. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:: Journal Article
MeSH Terms:: Ferroptosis*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Neuroprotective Agents*/metabolism
Hypoxia-Ischemia, Brain*/metabolism
Brain Injuries*/drug therapy
Brain Injuries*/metabolism
Humans ; Female ; Pregnancy ; Animals ; Rats ; Animals, Newborn ; Rats, Sprague-Dawley ; Serotonin/metabolism ; Hypoxia/metabolism ; Hippocampus/metabolism

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Skocz do pozycji: 10.

Tytuł:: Carbon Nitride-Based siRNA Vectors with Self-Produced O 2 Effects for Targeting Combination Therapy of Liver Fibrosis via HIF-1α-Mediated TGF-β1/Smad Pathway.
Autorzy:: Liu MX; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Xu L; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001, P. R. China.
Cai YT; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001, P. R. China.
Wang RJ; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Gu YY; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Liu YC; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001, P. R. China.
Zou YJ; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Zhao YM; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.
Chen J; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001, P. R. China.
Zhang XL; School of Pharmacy, Nantong University, Nantong, 226001, P. R. China.; Pokaż więcej
Źródło:: Advanced healthcare materials [Adv Healthc Mater] 2023 Nov; Vol. 12 (29), pp. e2301485. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Transforming Growth Factor beta1*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Mice ; Animals ; RNA, Small Interfering/genetics ; Liver Cirrhosis/therapy ; Hypoxia

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Skocz do pozycji: 11.

Tytuł:: Early Neuroprotective Effects of Bovine Lactoferrin Associated with Hypothermia after Neonatal Brain Hypoxia-Ischemia in Rats.
Autorzy:: Sanches E; Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 1205 Geneva, Switzerland.
van de Looij Y; Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 1205 Geneva, Switzerland.
Ho D; Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 1205 Geneva, Switzerland.
Modernell L; Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 1205 Geneva, Switzerland.
da Silva A; Center for Biomedical Imaging (CIBM), Animal Imaging and Technology Section, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Sizonenko S; Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 25; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Hypoxia-Ischemia, Brain*/pathology
Hypothermia*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Hypothermia, Induced*
Animals ; Rats ; Male ; Female ; Animals, Newborn ; Rats, Wistar ; Lactoferrin/pharmacology ; Lactoferrin/therapeutic use ; Brain/pathology ; Hypoxia/pathology ; Lactic Acid/pharmacology ; Inflammation/pathology ; RNA, Messenger

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Skocz do pozycji: 12.

Tytuł:: Longitudinal dynamics of the tumor hypoxia response: From enzyme activity to biological phenotype.
Autorzy:: Lee SCS; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
Pyo AHA; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
Koritzinsky M; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: Science advances [Sci Adv] 2023 Nov 24; Vol. 9 (47), pp. eadj6409. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Tumor Hypoxia*
Neoplasms*/metabolism
Humans ; Hypoxia ; Oxygen/metabolism ; Phenotype

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Skocz do pozycji: 13.

Tytuł:: Electrocatalytic on-site oxygenation for transplanted cell-based-therapies.
Autorzy:: Lee I; Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Surendran A; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Fleury S; Department of Bioengineering, Rice University, Houston, TX, USA.
Gimino I; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Curtiss A; Department of Electrical and Computer Engineering, Northwestern University, Evanston, IL, USA.
Fell C; Department of Bioengineering, Rice University, Houston, TX, USA.
Shiwarski DJ; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Refy O; Department of Physics, Carnegie Mellon University, Pittsburgh, PA, USA.
Rothrock B; Department of Computer Science, Northwestern University, Evanston, IL, USA.
Jo S; Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Schwartzkopff T; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Mehta AS; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Wang Y; Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Sipe A; Department of Material Science and Engineering, The Pennsylvania State University, State College, PA, USA.
John S; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, USA.
Ji X; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA.
Nikiforidis G; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Feinberg AW; Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Hester J; Interactive Computing and Computer Science, Georgia Institute of Technology, Atlanta, GA, USA.
Weber DJ; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, USA.; Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Veiseh O; Department of Bioengineering, Rice University, Houston, TX, USA.
Rivnay J; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. .; Simpson Querrey Institute, Northwestern University, Chicago, IL, USA. .; Department of Materials Science and Engineering, Northwestern University, Evanston, IL, 60208, USA. .
Cohen-Karni T; Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. .; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2023 Nov 09; Vol. 14 (1), pp. 7019. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Oxygen*
Hypoxia*
Humans ; Cell Hypoxia ; Respiratory Physiological Phenomena

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Skocz do pozycji: 14.

Tytuł:: Preterm Infants off Positive Pressure Respiratory Support Have a Higher Incidence of Occult Cerebral Hypoxia.
Autorzy:: Noroozi-Clever MB; Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO.
Liao SM; Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO.
Whitehead HV; Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO.
Vesoulis ZA; Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO. Electronic address: vesoulis_.; Pokaż więcej
Źródło:: The Journal of pediatrics [J Pediatr] 2023 Nov; Vol. 262, pp. 113648. Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:: Observational Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Infant, Premature*
Hypoxia, Brain*/etiology
Infant ; Infant, Newborn ; Humans ; Prospective Studies ; Incidence ; Hypoxia/etiology ; Oximetry/methods ; Continuous Positive Airway Pressure/adverse effects ; Oxygen

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Skocz do pozycji: 15.

Tytuł:: PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic-Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling.
Autorzy:: Zur Nedden S; Institute of Neurobiochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Safari MS; Institute of Neurobiochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Fresser F; Institute for Cell Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Faserl K; Protein Core Facility, Institute of Medical Biochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Lindner H; Protein Core Facility, Institute of Medical Biochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Sarg B; Protein Core Facility, Institute of Medical Biochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Baier G; Institute for Cell Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Baier-Bitterlich G; Institute of Neurobiochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Oct 31; Vol. 13 (11). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Hypoxia-Ischemia, Brain*/pathology
Neuroprotective Agents*
Animals ; Mice ; Proto-Oncogene Proteins c-akt/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Hypoxia ; Cerebellum/metabolism ; Animals, Newborn

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Skocz do pozycji: 16.

Tytuł:: Hypothermic Protection in Neocortex Is Topographic and Laminar, Seizure Unmitigating, and Partially Rescues Neurons Depleted of RNA Splicing Protein Rbfox3/NeuN in Neonatal Hypoxic-Ischemic Male Piglets.
Autorzy:: Primiani CT; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Lee JK; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
O'Brien CE; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Chen MW; Department Pediatrics, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Perin J; Department of Biostatistics and Epidemiology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Kulikowicz E; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Santos P; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Adams S; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Lester B; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Rivera-Diaz N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Olberding V; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Niedzwiecki MV; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Ritzl EK; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Habela CW; Department of Neurology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Liu X; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Yang ZJ; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Koehler RC; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.
Martin LJ; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; Department of Pathology, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; The Pathobiology Graduate Training Program, Johns Hopkins University School of Medicine, 558 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Oct 15; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Hypothermia*/pathology
Neocortex*/metabolism
Hypoxia-Ischemia, Brain*/pathology
Animals ; Male ; Swine ; Animals, Newborn ; Hypoxia/pathology ; Neurons/metabolism ; Ischemia/pathology ; Seizures

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1.
Autorzy:: Yang Z; National Experimental Teaching Center of Basic Medical Science, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China; Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Su W; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Wei X; The State Key Lab of Reproductive Medicine, Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qu S; School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Zhao D; Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhou J; National Experimental Teaching Center of Basic Medical Science, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Wang Y; Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Guan Q; Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Qin C; The State Key Lab of Reproductive Medicine, Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: .
Xiang J; Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: .
Zen K; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing, China. Electronic address: .
Yao B; National Experimental Teaching Center of Basic Medical Science, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China; Department of Medical Genetics, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China. Electronic address: .; Pokaż więcej
Źródło:: Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112945. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ferroptosis*
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Neoplasms*/genetics
Neoplasms*/pathology
Excitatory Amino Acid Transporter 3*/genetics
Animals ; Mice ; Cell Hypoxia ; Cell Line, Tumor ; Hypoxia ; Lactic Acid ; Tumor Microenvironment

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Skocz do pozycji: 18.

Tytuł:: ZBTB2 is Recruited to a Specific Subset of HIF-1 Target Loci to Facilitate Full Gene Expression Under Hypoxia.
Autorzy:: Chow CCT; Laboratory of Cancer Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Kobayashi M; Laboratory of Cancer Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan; Department of Genome Repair Dynamics, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Kambe G; Laboratory of Cancer Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.
Harada H; Laboratory of Cancer Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan; Department of Genome Repair Dynamics, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan. Electronic address: .; Pokaż więcej
Źródło:: Journal of molecular biology [J Mol Biol] 2023 Aug 01; Vol. 435 (15), pp. 168162. Date of Electronic Publication: 2023 May 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypoxia*/genetics
Hypoxia-Inducible Factor 1*/genetics
Hypoxia-Inducible Factor 1*/metabolism
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Humans ; Cell Hypoxia/genetics ; ErbB Receptors/genetics ; Gene Expression ; Gene Expression Regulation

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Skocz do pozycji: 19.

Tytuł:: Searching for molecular hypoxia sensors among oxygen-dependent enzymes.
Autorzy:: Li L; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, San Francisco, United States.
Shen S; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, San Francisco, United States.; Department of Psychiatry, University of California, San Francisco, San Francisco, United States.
Bickler P; Hypoxia Research Laboratory, University of California San Francisco, San Francisco, San Francisco, United States.; Center for Health Equity in Surgery and Anesthesia, University of California San Francisco, San Francisco, San Francisco, United States.; Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, San Francisco, United States.
Jacobson MP; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, San Francisco, United States.
Wu LF; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, San Francisco, United States.
Altschuler SJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, San Francisco, United States.; Pokaż więcej
Źródło:: ELife [Elife] 2023 Jul 26; Vol. 12. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:: Review; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypoxia*
Oxygen*/metabolism
Humans ; Gene Expression Regulation ; Transcription Factors/metabolism ; Procollagen-Proline Dioxygenase/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit ; Cell Hypoxia

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Szczegóły

Skocz do pozycji: 20.

Tytuł:: In Vivo Imaging of Tumor Hypoxia by Maintaining Green Fluorescence of 9-Aminoanthracene Under Hypoxic Conditions.
Autorzy:: Uchiyama Y; Department of Chemistry, School of Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan. Electronic address: .
Yamagishi S; Department of Chemistry, School of Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
Yamaura T; Department of Chemistry, School of Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
Kanazawa K; Department of Chemistry, School of Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
Maruyama H; Department of Cytopathology, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.; Pokaż więcej
Źródło:: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Aug 15; Vol. 91, pp. 117407. Date of Electronic Publication: 2023 Jul 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neoplasms*
Tumor Hypoxia*
Animals ; Mice ; Cell Hypoxia ; Diagnostic Imaging ; Fluorescence ; Hypoxia/diagnostic imaging ; Anthracenes/chemistry

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Hypoxia.