Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Hypoxia, Brain"" wg kryterium: Temat


Tytuł :
Sensitivity of a Next-Generation NIRS Device to Detect Low Mixed Venous Oxyhemoglobin Saturations in the Single Ventricle Population.
Autorzy :
Gagnon MH; From the *Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts †Department of Pediatrics, Harvard Medical School, Boston, Massachusetts ‡Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts §Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Kussman BD
Zhou L
DiNardo JA
Kheir JN
Pokaż więcej
Źródło :
Anesthesia and analgesia [Anesth Analg] 2020 Sep; Vol. 131 (3), pp. e138-e141.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiac Surgical Procedures*/adverse effects
Brain/*blood supply
Heart Defects, Congenital/*surgery
Hypoxia, Brain/*diagnosis
Oximetry/*instrumentation
Oxyhemoglobins/*metabolism
Spectroscopy, Near-Infrared/*instrumentation
Biomarkers/blood ; Equipment Design ; Humans ; Hypoxia, Brain/blood ; Hypoxia, Brain/etiology ; Infant, Newborn ; Predictive Value of Tests ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Trends, Predictors and Outcomes After Utilization of Targeted Temperature Management in Cardiac Arrest Patients With Anoxic Brain Injury.
Autorzy :
Khan MZ; Department of Medicine, West Virginia University, Morgantown, West Virginia.
Khan MU; Department of Medicine, West Virginia University, Morgantown, West Virginia.
Patel K; Division of Cardiovascular Medicine, West Virginia University Heart & Vascular Institute, Morgantown, West Virginia.
Khan SU; Department of Medicine, West Virginia University, Morgantown, West Virginia.
Valavoor S; Department of Medicine, West Virginia University, Morgantown, West Virginia.
Osman M; Division of Cardiovascular Medicine, West Virginia University Heart & Vascular Institute, Morgantown, West Virginia.
Balla S; Division of Cardiovascular Medicine, West Virginia University Heart & Vascular Institute, Morgantown, West Virginia.
Munir MB; Division of Cardiovascular Medicine, West Virginia University Heart & Vascular Institute, Morgantown, West Virginia; Section of Electrophysiology, Division of Cardiology, University of California San Diego, La Jolla, California. Electronic address: .
Pokaż więcej
Źródło :
The American journal of the medical sciences [Am J Med Sci] 2020 Oct; Vol. 360 (4), pp. 363-371. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries/*complications
Death, Sudden, Cardiac/*prevention & control
Hypothermia, Induced/*trends
Hypoxia, Brain/*complications
Aged ; Brain Injuries/mortality ; Death, Sudden, Cardiac/epidemiology ; Death, Sudden, Cardiac/etiology ; Female ; Humans ; Hypothermia, Induced/statistics & numerical data ; Hypoxia, Brain/mortality ; Logistic Models ; Male ; Middle Aged ; Treatment Outcome ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
Autorzy :
Letson HL; Heart, Trauma and Sepsis Research Laboratory, College of Medicine & Dentistry, James Cook University, Townsville, Queensland, Australia.
Granfeldt A; Aarhus University Hospital, Aarhus, Denmark.
Jensen TH; Aarhus University Hospital, Aarhus, Denmark.
Mattson TH; Aarhus University Hospital, Aarhus, Denmark.
Dobson GP; Heart, Trauma and Sepsis Research Laboratory, College of Medicine & Dentistry, James Cook University, Townsville, Queensland, Australia. Electronic address: .
Pokaż więcej
Źródło :
The Journal of surgical research [J Surg Res] 2020 Sep; Vol. 253, pp. 127-138. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Fluid Therapy/*methods
Hypotension/*therapy
Hypoxia, Brain/*prevention & control
Resuscitation/*methods
Shock, Hemorrhagic/*therapy
Adenosine/administration & dosage ; Animals ; Brain/drug effects ; Brain/metabolism ; Brain Chemistry/drug effects ; Disease Models, Animal ; Drug Administration Schedule ; Drug Therapy, Combination/methods ; Female ; Glycerol/analysis ; Humans ; Hypotension/etiology ; Hypoxia, Brain/etiology ; Hypoxia-Inducible Factor 1, alpha Subunit/analysis ; Infusions, Intravenous/methods ; Injections, Intravenous/methods ; Lactic Acid/analysis ; Lidocaine/administration & dosage ; Liver/blood supply ; Liver/injuries ; Magnesium/administration & dosage ; Oxygen/metabolism ; Shock, Hemorrhagic/etiology ; Stroke Volume/drug effects ; Sus scrofa ; Vascular Resistance/drug effects ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
Silencing of circular RNA ANRIL attenuates oxygen-glucose deprivation and reoxygenation-induced injury in human brain microvascular endothelial cells by sponging miR-622.
Autorzy :
Jiang S; Department of Rehabilitation, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Zhao G; Department of Rehabilitation, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Lu J; Department of Neurosurgery, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Jiang M; Department of Neurology, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Wu Z; Department of Neurology, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Huang Y; Department of Neurology, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Huang J; Department of Neurology, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Shi J; Department of Rehabilitation, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Jin J; Department of Rehabilitation, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Xu X; Department of Rehabilitation, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China.
Pu X; Department of Critical Care Medicine, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, People's Republic of China. .
Pokaż więcej
Źródło :
Biological research [Biol Res] 2020 Jul 02; Vol. 53 (1), pp. 27. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Hypoxia, Brain*/metabolism
MicroRNAs*/genetics
MicroRNAs*/physiology
RNA, Circular*
Reperfusion Injury*/metabolism
Apoptosis ; Brain ; Cyclin-Dependent Kinase Inhibitor p16 ; Endothelial Cells ; Glucose/metabolism ; Humans ; Inflammation ; Oxygen ; RNA, Long Noncoding
Czasopismo naukowe
Tytuł :
Acute Cerebellar Strokes with Anoxic Brain Injury After a Cardiopulmonary Arrest in SARS-CoV-2 Patient.
Autorzy :
Janjua T; Intensive Care Department, Regions Hospital, Saint Paul, Minnesota, United States. .
Moscote-Salazar LR
Pokaż więcej
Źródło :
Acta medica Indonesiana [Acta Med Indones] 2020 Apr; Vol. 52 (2), pp. 177-178.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coronavirus Infections*/diagnosis
Coronavirus Infections*/physiopathology
Coronavirus Infections*/therapy
Hypoxia, Brain*/diagnostic imaging
Hypoxia, Brain*/etiology
Pandemics*
Pneumonia, Viral*/diagnosis
Pneumonia, Viral*/physiopathology
Pneumonia, Viral*/therapy
Stroke*/diagnosis
Stroke*/etiology
Tomography, X-Ray Computed/*methods
Aged ; Betacoronavirus/isolation & purification ; Betacoronavirus/pathogenicity ; Female ; Heart Arrest/diagnosis ; Heart Arrest/etiology ; Heart Arrest/therapy ; Humans ; Patient Comfort/methods ; Respiration, Artificial/methods ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke.
Autorzy :
Fan AP; Department of Radiology, Stanford University, Stanford, CA, USA.
Khalil AA; Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Berlin School of Mind and Brain, Humboldt-Universitaet zu Berlin, Berlin, Germany.
Fiebach JB; Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.
Zaharchuk G; Department of Radiology, Stanford University, Stanford, CA, USA.
Villringer A; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Berlin School of Mind and Brain, Humboldt-Universitaet zu Berlin, Berlin, Germany.
Villringer K; Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.
Gauthier CJ; Department of Physics, Concordia University, Montreal, Canada.; Montreal Heart Institute, Montreal, Canada.
Pokaż więcej
Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2020 Mar; Vol. 40 (3), pp. 539-551. Date of Electronic Publication: 2019 Feb 07.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypoxia, Brain*/blood
Hypoxia, Brain*/diagnostic imaging
Magnetic Resonance Imaging*
Stroke*/blood
Stroke*/diagnostic imaging
Oxygen/*blood
Aged ; Aged, 80 and over ; Disease Susceptibility ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Perfusion
Czasopismo naukowe
Tytuł :
Statistical differences resulting from selection of stable reference genes after hypoxia and hypothermia in the neonatal rat brain.
Autorzy :
Bustelo M; Department of Pediatrics, Maastricht University Medical Center (MUMC), Maastricht, The Netherlands.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, The Netherlands.; Instituto de Ciencias Biomédicas, Facultad de Ciencias Médicas, Universidad Católica de Cuyo, San Juan, Argentina.; Laboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia 'Prof. E. De Robertis' (IBCN), Facultad de Medicina, Universidad de Buenos Aires, CONICET, Buenos Aires, Argentina.
Bruno MA; Instituto de Ciencias Biomédicas, Facultad de Ciencias Médicas, Universidad Católica de Cuyo, San Juan, Argentina.
Loidl CF; Instituto de Ciencias Biomédicas, Facultad de Ciencias Médicas, Universidad Católica de Cuyo, San Juan, Argentina.; Laboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia 'Prof. E. De Robertis' (IBCN), Facultad de Medicina, Universidad de Buenos Aires, CONICET, Buenos Aires, Argentina.
Rey-Funes M; Laboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia 'Prof. E. De Robertis' (IBCN), Facultad de Medicina, Universidad de Buenos Aires, CONICET, Buenos Aires, Argentina.
Steinbusch HWM; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, The Netherlands.
Gavilanes AWD; Department of Pediatrics, Maastricht University Medical Center (MUMC), Maastricht, The Netherlands.; Instituto de Investigación e Innovación de Salud Integral, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.
van den Hove DLA; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, The Netherlands.; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 May 21; Vol. 15 (5), pp. e0233387. Date of Electronic Publication: 2020 May 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Essential*
Brain/*metabolism
Gene Expression Profiling/*methods
Hypothermia/*genetics
Hypoxia, Brain/*genetics
Animals ; Animals, Newborn ; Gene Expression ; Hypothermia/metabolism ; Hypoxia, Brain/metabolism ; Rats ; Real-Time Polymerase Chain Reaction/methods ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Burden of hypoxia and intraventricular haemorrhage in extremely preterm infants.
Autorzy :
Ng IHX; Neonatal Unit, Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
da Costa CS; Neonatal Unit, Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Zeiler FA; Department of Medicine, Addenbrooke's Hospital Department of Anaesthesia, Cambridge, UK.; Section of Neurosurgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Wong FY; The Ritchie Centre, Monash University, Monash Institute of Medical Research, Clayton, Victoria, Australia.
Smielewski P; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Czosnyka M; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Austin T; Neonatal Unit, Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Pokaż więcej
Źródło :
Archives of disease in childhood. Fetal and neonatal edition [Arch Dis Child Fetal Neonatal Ed] 2020 May; Vol. 105 (3), pp. 242-247. Date of Electronic Publication: 2019 Jun 29.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Cerebral Hemorrhage/*epidemiology
Hypoxia, Brain/*epidemiology
Infant, Premature, Diseases/*epidemiology
Catheterization ; Cerebral Hemorrhage/physiopathology ; Cerebrovascular Circulation/physiology ; Female ; Gestational Age ; Humans ; Hypoxia, Brain/physiopathology ; Infant, Newborn ; Infant, Premature, Diseases/physiopathology ; Intensive Care Units, Neonatal ; Male ; Prospective Studies ; Spectroscopy, Near-Infrared ; Umbilical Arteries
Czasopismo naukowe
Tytuł :
Posthypoxic action myoclonus (the Lance-Adams syndrome).
Autorzy :
Marcellino C; Departments of Neurology and Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Wijdicks EF; Neurology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA .
Pokaż więcej
Źródło :
BMJ case reports [BMJ Case Rep] 2020 Apr 16; Vol. 13 (4). Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Case Reports; Video-Audio Media
MeSH Terms :
Hypoxia, Brain*
Myoclonus*
Heart Arrest/*complications
Humans ; Levetiracetam/therapeutic use ; Male ; Middle Aged ; Syndrome ; Valproic Acid/therapeutic use
Raport
Tytuł :
Anoxic Brain Injury Detection with the Normalized Diffusion to ASL Perfusion Ratio: Implications for Blood-Brain Barrier Injury and Permeability.
Autorzy :
Li N; From the Department of Radiology (N.L., M.A.W., J.P.N., D.R.P., and J.M.P.), Oregon Health & Science University, Portland, Oregon.
Wingfield MA; From the Department of Radiology (N.L., M.A.W., J.P.N., D.R.P., and J.M.P.), Oregon Health & Science University, Portland, Oregon.
Nickerson JP; From the Department of Radiology (N.L., M.A.W., J.P.N., D.R.P., and J.M.P.), Oregon Health & Science University, Portland, Oregon.
Pettersson DR; From the Department of Radiology (N.L., M.A.W., J.P.N., D.R.P., and J.M.P.), Oregon Health & Science University, Portland, Oregon.
Pollock JM; From the Department of Radiology (N.L., M.A.W., J.P.N., D.R.P., and J.M.P.), Oregon Health & Science University, Portland, Oregon .
Pokaż więcej
Źródło :
AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2020 Apr; Vol. 41 (4), pp. 598-606. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Blood-Brain Barrier/*diagnostic imaging
Diffusion Magnetic Resonance Imaging/*methods
Hypoxia, Brain/*diagnostic imaging
Image Interpretation, Computer-Assisted/*methods
Neuroimaging/*methods
Adult ; Blood-Brain Barrier/pathology ; Female ; Humans ; Hypoxia, Brain/pathology ; Male ; Perfusion Imaging/methods ; Retrospective Studies ; Sensitivity and Specificity ; Spin Labels ; Young Adult
Czasopismo naukowe
Tytuł :
Sex and age differentially affect GABAergic neurons in the mouse prefrontal cortex and hippocampus following chronic intermittent hypoxia.
Autorzy :
Rubin BR; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America. Electronic address: .
Milner TA; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America. Electronic address: .
Pickel VM; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America.
Coleman CG; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America.
Marques-Lopes J; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America.
Van Kempen TA; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, United States of America.
Kazim SF; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America; Department of Neurology, Icahn School of Medicine, Mount Sinai, New York, NY 10029, United States of America; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America.
McEwen BS; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America.
Gray JD; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America.
Pereira AC; Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065, United States of America; Department of Neurology, Icahn School of Medicine, Mount Sinai, New York, NY 10029, United States of America; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America. Electronic address: .
Pokaż więcej
Źródło :
Experimental neurology [Exp Neurol] 2020 Mar; Vol. 325, pp. 113075. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
GABAergic Neurons/*pathology
Hippocampus/*pathology
Hypoxia, Brain/*pathology
Prefrontal Cortex/*pathology
Age Factors ; Animals ; Cell Count ; Female ; Hippocampus/metabolism ; Hypoxia, Brain/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Prefrontal Cortex/metabolism ; Sex Characteristics
Czasopismo naukowe
Tytuł :
Survival and neurological outcome: Search for a low-hanging fruit.
Autorzy :
Bjørshol CA; The Regional Centre for Emergency Medical Research and Development (RAKOS), Hillevågsveien 8, NO-4016 Stavanger, Norway; Department of Anaesthesiology and Intensive Care, Stavanger University Hospital, P. O. Box 8100, NO-4068 Stavanger, Norway. Electronic address: .
Kramer-Johansen J; Oslo University Hospital, Oslo, Norway; University of Oslo, Oslo, Norway.
Pokaż więcej
Źródło :
Resuscitation [Resuscitation] 2020 Mar 01; Vol. 148, pp. 269-270. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Hypoxia, Brain*
Out-of-Hospital Cardiac Arrest*
Asphyxia ; Consciousness ; Humans ; Nursing Homes
Opinia redakcyjna
Tytuł :
α7 Nicotinic Acetylcholine Receptor Mediates the Neuroprotection of Remote Ischemic Postconditioning in a Rat Model of Asphyxial Cardiac Arrest.
Autorzy :
Han R; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China.
Zhang G; Department of Anesthesiology, Daxing Hospital, Xi'an, China.
Qiao X; Department of Anesthesiology, The Fourth People's Hospital of Shaanxi Province, Xi'an, China.
Guo Y; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China.
Sun L; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China.
Li J; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China.
Gao C; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China. Electronic address: .
Sun X; Department of Anesthesiology, The Second Affiliated Hospital of Air Force Medical University, Tangdu Hospital of Fourth Military Medical University, Xi'an, China. Electronic address: .
Pokaż więcej
Źródło :
The Journal of surgical research [J Surg Res] 2020 Feb; Vol. 246, pp. 6-18. Date of Electronic Publication: 2019 Sep 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ischemic Postconditioning*
Heart Arrest/*therapy
Hypoxia, Brain/*therapy
Neuroprotection/*physiology
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Animals ; Asphyxia/complications ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Disease Models, Animal ; Heart Arrest/etiology ; Hippocampus/blood supply ; Hippocampus/pathology ; Humans ; Hypoxia, Brain/etiology ; Hypoxia, Brain/pathology ; Male ; NF-kappa B/metabolism ; Neuroprotection/drug effects ; Quinuclidines/pharmacology ; Rats ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Treatment Outcome ; alpha7 Nicotinic Acetylcholine Receptor/agonists ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Higher physiological vulnerability to hypoxic exposure with advancing age in the human brain.
Autorzy :
Vestergaard MB; Functional Imaging Unit, Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark.
Jensen ML; Danish Centre for Sleep Medicine, Department of Clinical Neurophysiology, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark.
Arngrim N; Danish Headache Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark.
Lindberg U; Functional Imaging Unit, Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark.
Larsson HB; Functional Imaging Unit, Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark.
Pokaż więcej
Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2020 Feb; Vol. 40 (2), pp. 341-353. Date of Electronic Publication: 2018 Dec 12.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebrovascular Circulation*
Hypoxia, Brain*/diagnostic imaging
Hypoxia, Brain*/metabolism
Hypoxia, Brain*/physiopathology
Magnetic Resonance Imaging*
White Matter*/blood supply
White Matter*/metabolism
White Matter*/physiopathology
Aging/*metabolism
Adolescent ; Adult ; Female ; Humans ; Lactic Acid/metabolism ; Male ; Middle Aged ; Oxygen Consumption ; Pilot Projects
Czasopismo naukowe
Tytuł :
Total flavones of Rhododendron simsii Planch flower protect rat hippocampal neuron from hypoxia-reoxygenation injury via activation of BK Ca channel.
Autorzy :
Guo Y; Department of Pharmacology, Anhui Medical University, Hefei, China.
Yu XM; Department of Pharmacology, Anhui Medical University, Hefei, China.
Chen S; Department of Pharmacology, Anhui Medical University, Hefei, China.
Wen JY; Department of Pharmacology, Anhui Medical University, Hefei, China.
Chen ZW; Department of Pharmacology, Anhui Medical University, Hefei, China.
Pokaż więcej
Źródło :
The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2020 Jan; Vol. 72 (1), pp. 111-120. Date of Electronic Publication: 2019 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Flowers*/chemistry
Rhododendron*/chemistry
Flavones/*pharmacology
Hippocampus/*drug effects
Hypoxia, Brain/*drug therapy
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/*agonists
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Reperfusion Injury/*prevention & control
Animals ; Animals, Newborn ; Apoptosis/drug effects ; Cells, Cultured ; Flavones/isolation & purification ; Hippocampus/metabolism ; Hippocampus/pathology ; Hypoxia, Brain/metabolism ; Hypoxia, Brain/pathology ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/metabolism ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/isolation & purification ; Plant Extracts/isolation & purification ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Effects of regional body temperature variation during asphyxial cardiac arrest on mortality and brain damage in a rat model.
Autorzy :
Kim YS; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea; Department of Emergency Medicine, Samcheok Medical Center, Samcheok, Kangwon, 25920, Republic of Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Park Y; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Park CW; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Chonbuk, 54596, Republic of Korea.
Cho JH; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Chonbuk, 54596, Republic of Korea.
Kim IS; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Chonbuk, 54596, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Park YE; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon, 24252, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk, 38066, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Kangnung-Wonju National University, Gangneung, Gangwon, 25457, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. Electronic address: .
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło :
Journal of thermal biology [J Therm Biol] 2020 Jan; Vol. 87, pp. 102466. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Body Temperature*
Heart Arrest/*physiopathology
Hypothermia, Induced/*methods
Hypoxia, Brain/*physiopathology
Animals ; Brain/pathology ; Brain/physiopathology ; Cell Death ; Hypoxia, Brain/prevention & control ; Hypoxia, Brain/therapy ; Male ; Neurons/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Detailed statistical analysis plan for the SafeBoosC III trial: a multinational randomised clinical trial assessing treatment guided by cerebral oxygenation monitoring versus treatment as usual in extremely preterm infants.
Autorzy :
Hansen ML; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark. .
Pellicer A; Department of Neonatology, La Paz University Hospital, Paseo De La Castellana 261, 28046, Madrid, Spain.
Gluud C; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Dempsey E; Infant Centre and Department of Paediatrics and Child Health, University College Cork, College Road, Cork, Ireland.
Mintzer J; Division of Neonatal-Perinatal Medicine, Mountainside Medical Center, Montclair, NJ, USA.
Hyttel-Sorensen S; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Heuchan AM; Department of Neonatology, Royal Hospital for Children, 1345 Govan Rd, Glasgow, G51 4TF, UK.
Hagmann C; Department of Neonatology, Children's University Hospital of Zürich, Steinweisstrasse 75, 8037, Zurich, Switzerland.
Dimitriou G; NICU, Department of Pediatrics, University General Hospital of Patras, 265 04, Patras, Greece.
Pichler G; Department of Pediatrics, Medical University of Graz, Auenbruggerplatz 30, Graz, Austria.
Naulaers G; Department of Neonatology, University Hospital Leuven, Herestraat 49, Leuven, Belgium.
Cheng G; Department of Neonatology, Children's Hospital of Fudan University, 399 Wanyuan Rd, Minhang Qu, Shanghai Shi, China.
Vilan A; Department of Neonatology, Centrohospitalar Universitário de São João, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Tkaczyk J; Department of Neonatology, University Hospital Motol, V Uvalu 84, 150 06, Prague 5, Czech Republic.
Kreutzer KB; Department of Neonatology, University Children's Hospital Tuebingen, Hoppe-Seyler-Straße 1, 72076, Tuebingen, Germany.
Fumagalli M; Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milan, Via della Commenda 12, 20122, Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Claris O; Department of Neonatology, Hospices Civil De Lyon, 3 Quai des Célestins, 69002, Lyon, France.
Fredly S; Department of Neonatology, Oslo University Hospital, Kirkeveien, 166 0450, Oslo, Norway.
Szczapa T; Department of Neonatology, Poznan University of Medical Sciences, Polna 33, 60-535, Poznań, Poland.
Lange T; Section of Biostatistics, Department of Publich Health, Copenhagen University, Øster Farimagsgade 5, Copenhagen K, Denmark.; Center for Statistical Science, Peking University, Beijing, China.
Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Cardiology, Holbæk Hospital, Smedelundsgade 60, 4300, Holbæk, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Greisen G; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Pokaż więcej
Źródło :
Trials [Trials] 2019 Dec 19; Vol. 20 (1), pp. 746. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Letter
MeSH Terms :
Infant, Extremely Premature*
Brain/*diagnostic imaging
Emergency Treatment/*methods
Hypoxia, Brain/*therapy
Monitoring, Physiologic/*methods
Oxygen/*metabolism
Brain/metabolism ; Brain/pathology ; Clinical Trials, Phase III as Topic ; Humans ; Hypoxia, Brain/diagnosis ; Hypoxia, Brain/epidemiology ; Infant, Newborn ; Intensive Care Units, Neonatal ; Monitoring, Physiologic/instrumentation ; Multicenter Studies as Topic ; Pragmatic Clinical Trials as Topic ; Randomized Controlled Trials as Topic ; Spectroscopy, Near-Infrared/instrumentation ; Spectroscopy, Near-Infrared/methods
Opinia redakcyjna
Tytuł :
The expression of glucose transporters and mitochondrial division and fusion proteins in rats exposed to hypoxic preconditioning to attenuate propofol neurotoxicity.
Autorzy :
Xiao F; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Lv J; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Liang YB; Department of Anesthesiology, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.
Chen YH; Department of Anesthesiology, Cardiovascular Institute, Nanning, China.
Tu YB; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Guan RC; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Li L; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xie YB; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Pokaż więcej
Źródło :
The International journal of neuroscience [Int J Neurosci] 2020 Feb; Vol. 130 (2), pp. 161-169. Date of Electronic Publication: 2019 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Dynamins*/drug effects
Dynamins*/metabolism
GTP Phosphohydrolases*/drug effects
GTP Phosphohydrolases*/metabolism
Glucose Transporter Type 1*/drug effects
Glucose Transporter Type 1*/metabolism
Glucose Transporter Type 3*/drug effects
Glucose Transporter Type 3*/metabolism
Hippocampus*/drug effects
Hippocampus*/metabolism
Hypoxia, Brain*/metabolism
Mitochondria*/drug effects
Mitochondria*/metabolism
Mitochondrial Proteins*/drug effects
Mitochondrial Proteins*/metabolism
Neurons*/drug effects
Neurons*/metabolism
Hypnotics and Sedatives/*toxicity
Neurotoxicity Syndromes/*prevention & control
Propofol/*toxicity
Animals ; Animals, Newborn ; Disease Models, Animal ; Hypnotics and Sedatives/administration & dosage ; Male ; Propofol/administration & dosage ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia.
Autorzy :
Perekopskiy D; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA.
Afzal A; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA.
Jackson SN; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA.
Muller L; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA.
Woods AS; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA.
Kiyatkin EA; Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, 333 Cassell Drive, Baltimore, MD, 21224, USA. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Jan 21; Vol. 10 (1), pp. 833. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Heroin/*adverse effects
Hypoxia, Brain/*etiology
Receptors, Opioid/*physiology
Animals ; Blood-Brain Barrier/metabolism ; Brain/metabolism ; Hypoxia, Brain/drug therapy ; Naloxone/administration & dosage ; Naloxone/analogs & derivatives ; Naloxone/metabolism ; Naloxone/pharmacology ; Oxygen/metabolism ; Quaternary Ammonium Compounds/administration & dosage ; Quaternary Ammonium Compounds/metabolism ; Quaternary Ammonium Compounds/pharmacology ; Rats ; Receptors, Opioid/metabolism
Czasopismo naukowe
Tytuł :
Antioxidant enzymes expression in lymphocytes of patients undergoing carotid endarterectomy.
Autorzy :
Obradovic M; Vinca Institute of Nuclear Sciences, University of Belgrade, Laboratory of Radiobiology and Molecular Genetics, Mike Petrovica Alasa 12-14, 11000 Belgrade, Serbia. Electronic address: .
Zafirovic S; Vinca Institute of Nuclear Sciences, University of Belgrade, Laboratory of Radiobiology and Molecular Genetics, Mike Petrovica Alasa 12-14, 11000 Belgrade, Serbia.
Essack M; King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal 23955-6900, Saudi Arabia.
Dimitrov J; Vinca Institute of Nuclear Sciences, University of Belgrade, Laboratory of Radiobiology and Molecular Genetics, Mike Petrovica Alasa 12-14, 11000 Belgrade, Serbia.
Zivkovic L; Faculty of Pharmacy, Department of Physiology, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Spremo-Potparevic B; Faculty of Pharmacy, Department of Physiology, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Radak D; Serbian Academy of Sciences and Arts, Belgrade, Serbia.
Bajic VB; King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal 23955-6900, Saudi Arabia.
Isenovic ER; Vinca Institute of Nuclear Sciences, University of Belgrade, Laboratory of Radiobiology and Molecular Genetics, Mike Petrovica Alasa 12-14, 11000 Belgrade, Serbia.
Pokaż więcej
Źródło :
Medical hypotheses [Med Hypotheses] 2020 Jan; Vol. 134, pp. 109419. Date of Electronic Publication: 2019 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*enzymology
Catalase/*biosynthesis
Endarterectomy, Carotid/*adverse effects
Hypoxia, Brain/*enzymology
Intraoperative Complications/*enzymology
Lymphocytes/*enzymology
Superoxide Dismutase/*biosynthesis
Superoxide Dismutase-1/*biosynthesis
Brain Ischemia/etiology ; Carotid Stenosis/enzymology ; Carotid Stenosis/surgery ; Catalase/blood ; Catalase/genetics ; DNA Damage ; Free Radicals ; Gene Expression Regulation, Enzymologic ; Humans ; Hypoxia, Brain/etiology ; Intraoperative Complications/etiology ; Mitochondria/metabolism ; Models, Biological ; Oxidative Stress ; Reperfusion Injury/enzymology ; Reperfusion Injury/etiology ; Superoxide Dismutase/blood ; Superoxide Dismutase/genetics ; Superoxide Dismutase-1/blood ; Superoxide Dismutase-1/genetics
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies