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Tytuł:
Oxygen imaging of hypoxic pockets in the mouse cerebral cortex.
Autorzy:
Beinlich FRM; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Asiminas A; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Untiet V; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Bojarowska Z; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Plá V; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Sigurdsson B; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Timmel V; School of Engineering, FHNW University of Applied Sciences and Arts Northwestern Switzerland, 5210 Windisch, Switzerland.
Gehrig L; School of Engineering, FHNW University of Applied Sciences and Arts Northwestern Switzerland, 5210 Windisch, Switzerland.
Graber MH; School of Engineering, FHNW University of Applied Sciences and Arts Northwestern Switzerland, 5210 Windisch, Switzerland.
Hirase H; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Nedergaard M; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. 1471-1478. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cerebral Cortex*/blood supply
Cerebral Cortex*/diagnostic imaging
Cerebral Cortex*/metabolism
Oxygen*/blood
Oxygen*/metabolism
Cerebrovascular Circulation*
Hypoxia, Brain*/blood
Hypoxia, Brain*/diagnostic imaging
Hypoxia, Brain*/metabolism
Luminescent Measurements*/methods
Oxygen Saturation*
Animals ; Mice ; Partial Pressure ; Vasodilation ; Luciferases/genetics ; Luciferases/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Hypercapnia/blood ; Hypercapnia/diagnostic imaging ; Hypercapnia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alfaxalone is an effective anesthetic for the electrophysiological study of anoxia-tolerance mechanisms in western painted turtle pyramidal neurons.
Autorzy:
Suganthan H; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
Stefano DD; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
Buck LT; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.; Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0298065. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Turtles*/physiology
Hypoxia, Brain*
Anesthetics*/pharmacology
Pregnanediones*
Animals ; Receptors, GABA-A/metabolism ; Pyramidal Cells/metabolism ; Hypoxia/metabolism ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Longitudinal serum neurofilament light kinetics in post-anoxic encephalopathy.
Autorzy:
Disanto G; Neurocenter of Southern Switzerland, Civic Hospital, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Villa M; Department of Cardiac Anesthesia and Intensive Care, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Maleska Maceski A; Department of Neurology, University Hospital and University of Basel, Basel, Switzerland.; Multiple Sclerosis Centre and Research Centre for Clinical Neurimmunology and Neuroscience (RC2NB), Departments of Biomedicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland.
Prosperetti C; Neurocenter of Southern Switzerland, Civic Hospital, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Gobbi C; Neurocenter of Southern Switzerland, Civic Hospital, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Kuhle J; Department of Neurology, University Hospital and University of Basel, Basel, Switzerland.; Multiple Sclerosis Centre and Research Centre for Clinical Neurimmunology and Neuroscience (RC2NB), Departments of Biomedicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland.
Cassina T; Department of Cardiac Anesthesia and Intensive Care, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Agazzi P; Neurocenter of Southern Switzerland, Civic Hospital, Ente Ospedaliero Cantonale, Lugano, Switzerland.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2023 Dec; Vol. 10 (12), pp. 2407-2412. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia, Brain*
Heart Arrest*/complications
Humans ; Biomarkers ; Intermediate Filaments ; Neurofilament Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transient central hypoxemia due to intermittent high-degree atrioventricular block in a heart-transplanted patient diagnosed during routine electroencephalography: a case report.
Autorzy:
Raboud M; Department of Internal Medicine, University and Hospital of Fribourg, Chemin des Pensionnats 2-6, 1708, Fribourg, Switzerland.
Humm AM; Neurological Unit, Department of Internal Medicine, University and Hospital of Fribourg, Fribourg, Switzerland.
Vivekanantham H; Department of Cardiology, University and Hospital of Fribourg, Fribourg, Switzerland.
Suter P; Department of Internal Medicine, University and Hospital of Fribourg, Chemin des Pensionnats 2-6, 1708, Fribourg, Switzerland. .; Department of Pulmonary Medicine, University Hospital and University of Bern, Bern, Switzerland. .
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Źródło:
Journal of medical case reports [J Med Case Rep] 2023 Jan 06; Vol. 17 (1), pp. 3. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Atrioventricular Block*/diagnosis
Atrioventricular Block*/etiology
Atrioventricular Block*/therapy
Pacemaker, Artificial*/adverse effects
Vascular Diseases*/complications
Hypoxia, Brain*/etiology
Hypoxia, Brain*/complications
Male ; Humans ; Electroencephalography/adverse effects ; Hypoxia/diagnosis ; Hypoxia/etiology ; Electrocardiography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NLRP3 inflammasome regulates astrocyte transformation in brain injury induced by chronic intermittent hypoxia.
Autorzy:
She N; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Shi Y; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Feng Y; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Ma L; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Yuan Y; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Zhang Y; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Cao Z; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Chen X; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Zhao B; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China.
Liu H; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China. .
Ren X; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, No.157, Xiwu Road, Xi'an, 710004, Shaanxi, People's Republic of China. cor_.
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Źródło:
BMC neuroscience [BMC Neurosci] 2022 Nov 27; Vol. 23 (1), pp. 70. Date of Electronic Publication: 2022 Nov 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Inflammasomes*/genetics
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Sleep Apnea, Obstructive*/complications
Sleep Apnea, Obstructive*/genetics
Sleep Apnea, Obstructive*/metabolism
Hypoxia, Brain*/etiology
Hypoxia, Brain*/genetics
Hypoxia, Brain*/metabolism
Animals ; Rats ; Brain Injuries/genetics ; Brain Injuries/metabolism ; Caspases ; Hypoxia/etiology ; Hypoxia/genetics ; Hypoxia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intermittent hypoxic conditioning restores neurological dysfunction of mice induced by long-term hypoxia.
Autorzy:
Li G; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Guan Y; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Gu Y; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.
Guo M; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.
Ma W; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.
Shao Q; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.
Liu J; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.
Ji X; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-based Precision Medicine, Capital Medical University, Beijing, China.; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Jan; Vol. 29 (1), pp. 202-215. Date of Electronic Publication: 2022 Nov 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tumor Necrosis Factor-alpha*
Hypoxia, Brain*
Mice ; Animals ; Interleukin-6 ; Hypoxia ; Neurons ; Microglia
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brain hypoxia caused by respiratory obstruction which should not be forgotten in COVID-19 disease.
Autorzy:
Urakov A; Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia,Department of Modeling and Synthesis of Technological Processes, Udmurt Federal Research Center Ural Branch of the Russian Academy of Sciences, Izhevsk, Russia.
Muhutdinov N; Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia.
Yagudin I; Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia.
Sunstsova D; Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia.
Svetova M; Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia.
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Źródło:
Turkish journal of medical sciences [Turk J Med Sci] 2022 Oct; Vol. 52 (5), pp. 1504-1505. Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/complications
Hypoxia, Brain*
Humans ; Memory Disorders
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rationale and methods of the Antioxidant and NMDA receptor blocker Weans Anoxic brain damage of KorEa OHCA patients (AWAKE) trial.
Autorzy:
Choi JH; Samsung Medical Center, Department of Emergency Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. .
Chun BJ; Chonnam National University Hospital, Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Yeom SR; Pusan National University Hospital, Department of Emergency Medicine, Pusan National University School of Medicine, Busan, Republic of Korea.
Chung SP; Gangnam Severance Hospital, Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Lee YH; Department of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon-si, Gyeonggi-do, Republic of Korea.
Kim YH; Samsung Medical Center, Department of Physical and Rehabilitation Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lee JS; Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Lee JH; GNT Pharma Co. Ltd, Yongin-si, Gyeonggi-Do, Republic of Korea.
Lee HG; GNT Pharma Co. Ltd, Yongin-si, Gyeonggi-Do, Republic of Korea.
Jin JY; GNT Pharma Co. Ltd, Yongin-si, Gyeonggi-Do, Republic of Korea.
An CS; GNT Pharma Co. Ltd, Yongin-si, Gyeonggi-Do, Republic of Korea.
Gwag BJ; GNT Pharma Co. Ltd, Yongin-si, Gyeonggi-Do, Republic of Korea.
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Źródło:
Trials [Trials] 2022 Jul 23; Vol. 23 (1), pp. 587. Date of Electronic Publication: 2022 Jul 23.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Brain Injuries*
Hypoxia, Brain*
Out-of-Hospital Cardiac Arrest*/diagnosis
Out-of-Hospital Cardiac Arrest*/drug therapy
Adult ; Antioxidants/adverse effects ; Humans ; Prospective Studies ; Receptors, N-Methyl-D-Aspartate/therapeutic use ; Treatment Outcome ; Wakefulness
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Un-biased housekeeping gene panel selection for high-validity gene expression analysis.
Autorzy:
Casas AI; Department of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Clinics Essen, Essen, Germany. .; Department of Pharmacology & Personalised Medicine, MeHNS, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. .
Hassan AA; Department of Pharmacology & Personalised Medicine, MeHNS, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Manz Q; Faculty of Mathematics, Informatics and Natural Sciences, University of Hamburg, Hamburg, Germany.
Wiwie C; Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark.
Kleikers P; Department of Pharmacology & Personalised Medicine, MeHNS, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Egea J; Molecular Neuroinflammation and Neuronal Plasticity Research Laboratory, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria-Hospital Universitario de la Princesa, Madrid, Spain.; Departamento de Farmacología, Instituto de I+D del Medicamento Teófilo Hernando (ITH), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.
López MG; Departamento de Farmacología, Instituto de I+D del Medicamento Teófilo Hernando (ITH), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.
List M; Chair of Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Baumbach J; Faculty of Mathematics, Informatics and Natural Sciences, University of Hamburg, Hamburg, Germany.
Schmidt HHHW; Department of Pharmacology & Personalised Medicine, MeHNS, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 19; Vol. 12 (1), pp. 12324. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article; Systematic Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, Essential*
Hypoxia, Brain*
Algorithms ; Gene Expression ; Gene Expression Profiling ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms of hypoxia in the hippocampal CA3 region in postoperative cognitive dysfunction after cardiopulmonary bypass.
Autorzy:
Liu T; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.; Laboratory of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Deng R; Department of Anesthesiology, People's Hospital of Deyang City, Deyang, 618000, China.
Wang X; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.
Liu P; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.
Xiao QX; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.; Laboratory of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Liu Q; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China. .
Zhang Y; Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2022 May 07; Vol. 17 (1), pp. 106. Date of Electronic Publication: 2022 May 07.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia, Brain*/etiology
Postoperative Cognitive Complications*/etiology
Aged ; Animals ; CA3 Region, Hippocampal ; Cardiopulmonary Bypass/adverse effects ; Humans ; Hypoxia ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation.
Autorzy:
Kim SR; Department of Oral Physiology, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Seong KJ; Department of Oral Physiology, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Kim WJ; Department of Oral Physiology, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Jung JY; Department of Oral Physiology, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 04; Vol. 23 (7). Date of Electronic Publication: 2022 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Catechin*/analogs & derivatives
Catechin*/pharmacology
Hypoxia, Brain*/metabolism
Microglia*/metabolism
Humans ; Cyclooxygenase 2/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides ; NF-kappa B/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MiR-17-5p inhibits cerebral hypoxia/reoxygenationinjury by targeting PTEN through regulation of PI3K/AKT/mTOR signaling pathway.
Autorzy:
Ren X; Department of Neurology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, PR China.
Jing YX; Department of Emergency, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, PR China.
Zhou ZW; Department of Neurology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, PR China.
Yang QM; Department of Neurology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, PR China.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2022 Feb; Vol. 132 (2), pp. 192-200. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia, Brain*
MicroRNAs*/metabolism
Apoptosis ; Endothelial Cells/metabolism ; Humans ; PTEN Phosphohydrolase/metabolism ; PTEN Phosphohydrolase/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Early cerebral hypoxia in extremely preterm infants and neurodevelopmental impairment at 2 year of age: A post hoc analysis of the SafeBoosC II trial.
Autorzy:
Plomgaard AM; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Schwarz CE; Department of Neonatology, University Children's Hospital, Tuebingen, Germany.; INFANT Centre, University College Cork, Cork, Ireland.
Claris O; Department of Neonatology, Hospices Civils de Lyon, Claude Bernard University, Lyon, France.
Dempsey EM; INFANT Centre, University College Cork, Cork, Ireland.
Fumagalli M; NICU, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Hyttel-Sorensen S; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Lemmers P; Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Pellicer A; Department of Neonatology, La Paz University Hospital, Madrid, Spain.
Pichler G; Department of Pediatrics, Medical University of Graz, Graz, Austria.
Greisen G; Department of Neonatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
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Źródło:
PloS one [PLoS One] 2022 Jan 24; Vol. 17 (1), pp. e0262640. Date of Electronic Publication: 2022 Jan 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypoxia, Brain/*complications
Infant, Extremely Premature/*growth & development
Neurodevelopmental Disorders/*etiology
Child, Preschool ; Female ; Humans ; Hypoxia, Brain/etiology ; Hypoxia, Brain/prevention & control ; Hypoxia, Brain/therapy ; Infant ; Infant, Newborn ; Male ; Spectroscopy, Near-Infrared/methods ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Maternal N-Acetyl-Cysteine Prevents Neonatal Hypoxia-Induced Brain Injury in a Rat Model.
Autorzy:
Gutziet O; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Iluz R; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ben Asher H; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Segal L; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ben Zvi D; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ginsberg Y; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Khatib N; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Zmora O; Department of Pediatric Surgery, Shamir Medical Center, Tzrifin 7073001, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Ross MG; Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and The Lundquist Institute, Torrance, CA 92270, USA.
Weiner Z; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Beloosesky R; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 20; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation*
Oxidative Stress*
Acetylcysteine/*metabolism
Asphyxia Neonatorum/*complications
Brain/*metabolism
Hypoxia, Brain/*prevention & control
Animals ; Animals, Newborn ; Antioxidants/metabolism ; Gene Expression Regulation ; Hypoxia, Brain/etiology ; Hypoxia, Brain/metabolism ; In Situ Nick-End Labeling ; Interleukin-6/genetics ; Nitric Oxide Synthase Type I/genetics ; Rats ; Rats, Sprague-Dawley ; Transcription Factor RelA/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
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Tytuł:
Posttreatment Strategy Against Hypoxia and Ischemia Based on Selective Targeting of Nonnuclear Estrogen Receptors with PaPE-1.
Autorzy:
Wnuk A; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Neuropharmacology and Epigenetics, Smętna Street 12, 31-343, Krakow, Poland. .
Przepiórska K; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Neuropharmacology and Epigenetics, Smętna Street 12, 31-343, Krakow, Poland.
Pietrzak BA; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Neuropharmacology and Epigenetics, Smętna Street 12, 31-343, Krakow, Poland.
Kajta M; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pharmacology, Laboratory of Neuropharmacology and Epigenetics, Smętna Street 12, 31-343, Krakow, Poland. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 2029-2041. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/drug therapy
Estradiol Congeners*/therapeutic use
Hypoxia, Brain*/drug therapy
Indans*/pharmacology
Indans*/therapeutic use
Receptors, Estrogen*/drug effects
Animals ; Mice ; Caspase 3/metabolism ; Cells, Cultured ; L-Lactate Dehydrogenase/metabolism ; Neurons/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
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Tytuł:
Brain tissue oxygenation guided therapy and outcome in non-traumatic subarachnoid hemorrhage.
Autorzy:
Gouvea Bogossian E; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium. .
Diaferia D; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Ndieugnou Djangang N; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Menozzi M; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Vincent JL; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Talamonti M; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Dewitte O; Department of Neurosurgery, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Peluso L; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Barrit S; Department of Neurosurgery, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Al Barajraji M; Department of Neurosurgery, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Andre J; Department of Radiology, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Schuind S; Department of Neurosurgery, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Creteur J; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
Taccone FS; Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Route de Lennik, 808, 1070, Brussels, Belgium.
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 10; Vol. 11 (1), pp. 16235. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Outcome Assessment, Health Care*
Hypoxia, Brain/*therapy
Oxygen/*administration & dosage
Oxygen Inhalation Therapy/*methods
Subarachnoid Hemorrhage/*therapy
Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Hypoxia, Brain/pathology ; Male ; Middle Aged ; Prognosis ; Subarachnoid Hemorrhage/pathology ; Survival Rate
Czasopismo naukowe
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Tytuł:
Glucocorticoid-Dependent Mechanisms of Brain Tolerance to Hypoxia.
Autorzy:
Rybnikova E; I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 Saint Petersburg, Russia.
Nalivaeva N; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 194223 Saint Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Disease Resistance*
Ischemic Preconditioning*
Signal Transduction*
Glucocorticoids/*metabolism
Hypothalamo-Hypophyseal System/*metabolism
Hypoxia, Brain/*metabolism
Pituitary-Adrenal System/*metabolism
Animals ; Humans ; Hypothalamo-Hypophyseal System/pathology ; Hypoxia, Brain/prevention & control ; Pituitary-Adrenal System/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of neurotropism in psychiatric patients with COVID-19.
Autorzy:
Diaz AD; Department of Psychiatry and Behavior Health, Penn State University College of Medicine, 500 University Drive, H073, Hershey, PA, 17033-0850, USA.
Baweja R; Department of Psychiatry and Behavior Health, Penn State University College of Medicine, 500 University Drive, H073, Hershey, PA, 17033-0850, USA. .
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Źródło:
European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2021 Mar; Vol. 271 (2), pp. 385-386. Date of Electronic Publication: 2020 Sep 27.
Typ publikacji:
Letter
MeSH Terms:
Brain*
Anxiety/*psychology
COVID-19/*psychology
Depression/*psychology
Hypoxia, Brain/*psychology
SARS-CoV-2/*physiology
Stress Disorders, Post-Traumatic/*psychology
Viral Tropism/*physiology
Axonal Transport ; COVID-19/physiopathology ; Humans ; Hypoxia, Brain/physiopathology ; Limbic System ; Mental Disorders/psychology ; Olfactory Bulb ; Risk Factors ; Suicidal Ideation
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MicroRNA-9 mediated the protective effect of ferulic acid on hypoxic-ischemic brain damage in neonatal rats.
Autorzy:
Yao K; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
Yang Q; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
Li Y; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
Lan T; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
Yu H; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
Yu Y; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Sichuan Province, China.
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Źródło:
PloS one [PLoS One] 2020 May 29; Vol. 15 (5), pp. e0228825. Date of Electronic Publication: 2020 May 29 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coumaric Acids/*pharmacology
Hypoxia, Brain/*drug therapy
Hypoxia-Ischemia, Brain/*drug therapy
MicroRNAs/*genetics
Animals ; Animals, Newborn ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Hippocampus/drug effects ; Hippocampus/pathology ; Humans ; Hypoxia, Brain/genetics ; Hypoxia, Brain/pathology ; Hypoxia-Ischemia, Brain/genetics ; Hypoxia-Ischemia, Brain/pathology ; Neurons/drug effects ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Rats
Czasopismo naukowe
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Wyświetlanie 1-20 z 330

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