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Tytuł:
Gut microbiome for predicting immune checkpoint blockade-associated adverse events.
Autorzy:
Hu M; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Lin X; Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Sun T; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Shao X; Department of Medical Oncology, Xuzhou Central Hospital, Clinical School of Xuzhou Medical University, Xuzhou, 221009, China.
Huang X; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Du W; Department of Medical Oncology, Xuzhou Central Hospital, Clinical School of Xuzhou Medical University, Xuzhou, 221009, China.
Guo M; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China.
Zhu X; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Zhou Y; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Tong T; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China.
Guo F; Department of Gastroenterology, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, China.
Han T; Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Wu X; Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Shi Y; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China.
Xiao X; Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China. .
Zhang Y; Department of Medical Oncology, Xuzhou Central Hospital, Clinical School of Xuzhou Medical University, Xuzhou, 221009, China. .
Hong J; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China. .
Chen H; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai, 200001, China. .
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Źródło:
Genome medicine [Genome Med] 2024 Jan 19; Vol. 16 (1), pp. 16. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/drug therapy
Gastrointestinal Microbiome*
Antineoplastic Agents, Immunological*/therapeutic use
Drug-Related Side Effects and Adverse Reactions*
Immune System Diseases*
Lung Neoplasms*/drug therapy
Humans ; Immune Checkpoint Inhibitors/therapeutic use ; RNA, Ribosomal, 16S/genetics ; Vitamin K 2/therapeutic use ; Immunotherapy/adverse effects ; Programmed Cell Death 1 Receptor ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Gender and the length of time since autologous hematopoietic stem cell transplantation-What is their influence on the immune reconstitution in multiple myeloma patients?
Autorzy:
Popierz-Rydlewska N; Team of Food and Nutrition, Department of Dietetics, Faculty of Health Sciences, Poznan University of Physical Education, Poznań, Poland.
Merkiel-Pawłowska S; Team of Food and Nutrition, Department of Dietetics, Faculty of Health Sciences, Poznan University of Physical Education, Poznań, Poland.
Łojko-Dankowska A; Department of Haematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznań, Poland.
Komarnicki M; Poznan University of Medical Sciences, Poznań, Poland.
Chalcarz W; Poznan University of Physical Education, Poznań, Poland.
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Źródło:
PloS one [PLoS One] 2023 Dec 07; Vol. 18 (12), pp. e0295308. Date of Electronic Publication: 2023 Dec 07 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Myeloma*/therapy
Immune Reconstitution*
Hematopoietic Stem Cell Transplantation*/methods
Humans ; Male ; Female ; Transplantation, Autologous ; Immune System
Czasopismo naukowe
Tytuł:
The Role of Immune Dysfunction in Parkinson's Disease Development.
Autorzy:
Cossu D; Department of Neurology, Juntendo University, Tokyo 1138431, Japan.; Department of Biomedical Sciences, Sassari University, 07100 Sassari, Italy.
Hatano T; Department of Neurology, Juntendo University, Tokyo 1138431, Japan.
Hattori N; Department of Neurology, Juntendo University, Tokyo 1138431, Japan.; Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Saitama 3510918, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 26; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*
Immune System Diseases*
Humans ; Inflammation ; Adaptive Immunity ; Immune System
Czasopismo naukowe
Tytuł:
Immune Checkpoint Inhibitors and Associated Pituitary Dysfunctions: A Mini-Review.
Autorzy:
Fukuda I; Department of Endocrinology, Metabolism and Nephrology, Graduate School of Medicine, Nippon Medical School.
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Źródło:
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi [J Nippon Med Sch] 2023 May 30; Vol. 90 (2), pp. 149-156. Date of Electronic Publication: 2023 Feb 21.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Neoplasms*/drug therapy
Hypophysitis*/chemically induced
Immune System Diseases*
Humans ; Immune Checkpoint Inhibitors ; Ligands ; Antibodies, Monoclonal/adverse effects
Czasopismo naukowe
Tytuł:
Gene Expression Profiling in Coeliac Disease Confirmed the Key Role of the Immune System and Revealed a Molecular Overlap with Non-Celiac Gluten Sensitivity.
Autorzy:
Sallese M; Department of Innovative Technologies in Medicine and Dentistry, University 'G. d'Annunzio' of Chieti-Pescara, 66100 Chieti, Italy.; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
Efthymakis K; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.; Department of Medicine and Ageing Sciences, 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
Marchioni M; Laboratory of Biostatistics, Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
Neri B; Gastroenterology Unit, Department of Systems Medicine, University 'Tor Vergata' of Rome, 00133 Roma, Italy.
Dufrusine B; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.; Department of Bioscience and Technology for Food Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Dainese E; Department of Bioscience and Technology for Food Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.
Di Nicola M; Laboratory of Biostatistics, Department of Medical, Oral and Biotechnological Sciences, 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
Neri M; Center for Advanced Studies and Technology (CAST), 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.; Department of Medicine and Ageing Sciences, 'G. d'Annunzio' University of Chieti-Pescara, 66100 Chieti, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 24; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Celiac Disease*
Immune System Diseases*
Humans ; Glutens/genetics ; Immunity, Innate/genetics ; Immune System/pathology ; Gene Expression Profiling
Czasopismo naukowe
Tytuł:
Strategies for improving the performance of prediction models for response to immune checkpoint blockade therapy in cancer.
Autorzy:
Zeng T; Department of Statistics, University of Kentucky, 725 Rose St, Lexington, KY, 40536, USA. .
Zhang JZ; Wake Forest University, Winston-Salem, NC, 27109, USA.
Stromberg A; Department of Statistics, University of Kentucky, 725 Rose St, Lexington, KY, 40536, USA.
Chen J; Department of Medicine - Nephrology, University of Alabama at Birmingham, 703 19th St S, Birmingham, AL, 35294, USA.
Wang C; Department of Internal Medicine, University of Kentucky, 800 Rose St, Lexington, KY, 40536, USA. .
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Źródło:
BMC research notes [BMC Res Notes] 2024 Apr 09; Vol. 17 (1), pp. 102. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*/pharmacology
Immune Checkpoint Inhibitors*/therapeutic use
Melanoma*/drug therapy
Melanoma*/genetics
Humans ; Knowledge ; Machine Learning ; RNA
Czasopismo naukowe
Tytuł:
Discovery of a novel small molecule as CD47/SIRPα and PD-1/PD-L1 dual inhibitor for cancer immunotherapy.
Autorzy:
Jin S; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Wang H; Henan Key Laboratory of Immunology and Targeted Drugs, School of Medical Technology, Xinxiang Medical University, Xinxiang, Henan, 453003, China.
Li Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yang J; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Li B; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Shi P; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Zhang X; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Zhou X; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Zhou X; School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, China.
Niu X; School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, China.
Wu M; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Wu Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.; International Joint Laboratory for Protein and Peptide Drugs of Henan Province, Zhengzhou University, Zhengzhou, 450001, China.
Zhai W; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.; International Joint Laboratory for Protein and Peptide Drugs of Henan Province, Zhengzhou University, Zhengzhou, 450001, China.
Qi Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Gao Y; School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, China. .
Zhao W; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 11; Vol. 22 (1), pp. 173. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immune Checkpoint Inhibitors*/pharmacology
Immune Checkpoint Inhibitors*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/pathology
Animals ; Mice ; Programmed Cell Death 1 Receptor ; CD8-Positive T-Lymphocytes ; CD47 Antigen/metabolism ; B7-H1 Antigen ; Phagocytosis ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Strategies for Overcoming Immune Evasion in Bladder Cancer.
Autorzy:
Shin J; Department of Health Sciences, The Graduate School of Dong-A University, Busan 49315, Republic of Korea.
Park JW; Department of Health Sciences, The Graduate School of Dong-A University, Busan 49315, Republic of Korea.
Kim SY; Department of Health Sciences, The Graduate School of Dong-A University, Busan 49315, Republic of Korea.
Lee JH; Department of Korean Medicine, College of Korean Medicine, Woosuk University, Jeonju 54986, Republic of Korea.
Choi WS; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
Kim HS; Department of Health Sciences, The Graduate School of Dong-A University, Busan 49315, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 07; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immune Evasion*
Urinary Bladder Neoplasms*/pathology
Humans ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Alpha-fetoprotein predicts the treatment efficacy of immune checkpoint inhibitors for gastric cancer patients.
Autorzy:
Zhang J; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China.
Wang L; Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, 050011, Shijiazhuang, Hebei, P.R. China.
Zhang S; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China.
Cao R; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China.
Zhao Y; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China.
Zhao Y; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China.
Song Y; Department of Medical Technology, Xingtai Medical College, 054000, Xingtai, Hebei, P.R. China.
Guo Z; Department of Immunology and Rheumatology, The Fourth Hospital of Hebei Medical University, 12 Jiankang Road, 050011, Shijiazhuang, Hebei, P.R. China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Feb 26; Vol. 24 (1), pp. 266. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*/therapeutic use
Stomach Neoplasms*/drug therapy
Humans ; alpha-Fetoproteins ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Magnetic resonance imaging-based approaches for detecting the efficacy of combining therapy following VEGFR-2 and PD-1 blockade in a colon cancer model.
Autorzy:
Xu X; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Ma M; Department of Radiology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, 510080, China.
Ye K; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Zhang D; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Chen X; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Wu J; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Mo X; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Xiao Z; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. .; The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, Jinan University, Guangzhou, 510632, China. .
Shi C; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. .; The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, Jinan University, Guangzhou, 510632, China. .
Luo L; Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. .; The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, Jinan University, Guangzhou, 510632, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 23; Vol. 22 (1), pp. 198. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/diagnostic imaging
Colonic Neoplasms*/drug therapy
Programmed Cell Death 1 Receptor*/antagonists & inhibitors
Immune Checkpoint Inhibitors*/therapeutic use
Animals ; Humans ; Mice ; Diffusion Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/methods ; Mice, Inbred C57BL ; Vascular Endothelial Growth Factor Receptor-2/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
Real-world treatment outcomes of immune checkpoint inhibitors used off-label in oncology: A comprehensive cancer institution experience.
Autorzy:
Fontanals S; Pharmacy Department, Catalan Institute of Oncology (ICO)- Hospitalet, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), School of Medicine, Universitat de Barcelona (UB), ICO, Hospitalet de Llobregat, Barcelona, Spain.
Esteve A; Research Management Unit (UGR), Catalan Institute of Oncology (ICO), Medical Oncology Department, ICO-Badalona, Applied Research Group in Oncology (B-ARGO), Germans Trias I Pujol Research Institute (IGTP), ICO, Badalona, Spain.
González A; Medical Oncology Department, Catalan Institute of Oncology (ICO), Badalona-Applied Research Group in Oncology (B-ARGO) Germans Trias I Pujol Research Institute (IGTP), ICO, Badalona, Spain.
Ibáñez C; Pharmacy Department, Catalan Institute of Oncology (ICO)-Hospitalet, Blanquerna Ramon Llull University, School of Health Sciences, ICO, Hospitalet de Llobregat, Barcelona, Spain.
Mesía R; Medical Oncology Department, Catalan Institute of Oncology (ICO), Badalona-Applied Research Group in Oncology (B-ARGO) Germans Trias I Pujol Research Institute (IGTP), ICO, Badalona, Spain.
Clopés A; Pharmacy Department, Catalan Institute of Oncology (ICO)-Hospitalet, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), School of Health Sciences, Blanquerna Ramon Llull University, ICO, Hospitalet de Llobregat, Barcelona, Spain.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Feb; Vol. 12 (1), pp. e1167.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*/therapeutic use
Neoplasms*/drug therapy
Male ; Humans ; Female ; Middle Aged ; Off-Label Use ; Medical Oncology ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Glucocorticoid-free remission in patients with SLE in the era of biologics: Immune complex disease is likely to benefit from current medications.
Autorzy:
Oiwa H; Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Suga T; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Hosokawa Y; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Araki K; Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
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Źródło:
Lupus [Lupus] 2024 Apr; Vol. 33 (5), pp. 502-510. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Products*/therapeutic use
Lupus Erythematosus, Systemic*/drug therapy
Immune Complex Diseases*/drug therapy
Humans ; Male ; Glucocorticoids/therapeutic use ; Retrospective Studies ; Severity of Illness Index ; Immunosuppressive Agents/therapeutic use ; Antigen-Antibody Complex
Czasopismo naukowe
Tytuł:
Interpretable machine learning-based individual analysis of acute kidney injury in immune checkpoint inhibitor therapy.
Autorzy:
Sakuragi M; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Uchino E; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sato N; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Matsubara T; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ueda A; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mineharu Y; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Artificial Intelligence in Healthcare and Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kojima R; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yanagita M; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan.
Okuno Y; Department of Biomedical Data Intelligence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło:
PloS one [PLoS One] 2024 Mar 19; Vol. 19 (3), pp. e0298673. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*/adverse effects
Acute Kidney Injury*/chemically induced
Humans ; Radioimmunotherapy ; Cachexia ; Machine Learning
Czasopismo naukowe
Tytuł:
Association of lymphocyte subsets with the efficacy and prognosis of PD‑1 inhibitor therapy in advanced gastric cancer: results from a monocentric retrospective study.
Autorzy:
Wang X; The First Clinical Medical College of Shanxi Medical University, No.56, Xinjian South Road, Yingze District, Taiyuan, Shanxi, 030001, People's Republic of China.; Department of Oncology, The First Hospital of Shanxi Medical University, No.85, Jiefang South Road, Yingze District, Taiyuan, Shanxi, 030001, People's Republic of China.
Liu X; Department of Special Medical, Shanxi Province Cancer Hospital, Taiyuan, Shanxi, 030013, China.
Dai H; The Second Clinical Medical College of Shanxi Medical University, Taiyuan, Shanxi, 030001, China.
Jia J; Department of Oncology, The First Hospital of Shanxi Medical University, No.85, Jiefang South Road, Yingze District, Taiyuan, Shanxi, 030001, People's Republic of China. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2024 Mar 15; Vol. 24 (1), pp. 113. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*
Stomach Neoplasms*/drug therapy
Humans ; B7-H1 Antigen ; Retrospective Studies ; Prognosis ; Lymphocyte Subsets
Czasopismo naukowe
Tytuł:
Immune Factors, Immune Cells and Inflammatory Diseases.
Autorzy:
Ward AC; School of Medicine, Deakin University, Geelong, VIC 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC 3216, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 19; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Editorial
MeSH Terms:
Immunity, Innate*
Immune System*
Immunologic Factors ; Adaptive Immunity
Opinia redakcyjna
Tytuł:
Mitigating non-genetic resistance to checkpoint inhibition based on multiple states of immune exhaustion.
Autorzy:
Kareva I; Quantitative Pharmacology Department, EMD Serono, Merck KGaA, Billerica, MA, USA. .; Department of Biomedical Engineering, Northeastern University, Boston, MA, USA. .
Gevertz JL; Department of Mathematics and Statistics, The College of New Jersey, Ewing, NJ, USA.
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Źródło:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Feb 09; Vol. 10 (1), pp. 14. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Immune System Exhaustion*
Inflammation*
Humans
Czasopismo naukowe
Tytuł:
Investigation of the potential effects of estrogen receptor modulators on immune checkpoint molecules.
Autorzy:
Abramenko N; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.
Vellieux F; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.
Veselá K; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.
Kejík Z; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.
Hajduch J; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.
Masařík M; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.; Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.; Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Babula P; Department of Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Hoskovec D; 1st Department of Surgery-Department of Abdominal, Thoracic Surgery and Traumatology, First Faculty of Medicine, Charles University and General University Hospital, U Nemocnice 2, 121 08, Prague, Czech Republic.
Pacák K; Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Room 1-3140, 10 Center Drive, Bethesda, MD, 20892, USA.
Martásek P; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic.
Smetana K Jr; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic.; Institute of Anatomy, First Faculty of Medicine, Charles University, 120 00, Prague, Czech Republic.
Jakubek M; BIOCEV, First Faculty of Medicine, Charles University, 252 50, Vestec, Czech Republic. .; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, 120 00, Prague, Czech Republic. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 06; Vol. 14 (1), pp. 3043. Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Proteins*
Neoplasms*/therapy
Humans ; CTLA-4 Antigen ; B7-H1 Antigen ; Selective Estrogen Receptor Modulators/pharmacology ; Programmed Cell Death 1 Receptor ; Estrogen Receptor Modulators ; Quercetin ; Immunotherapy
Czasopismo naukowe
Tytuł:
Single-Cell Atlas of Atherosclerosis Patients by Cytof: Circulatory and Local Immune Disorders.
Autorzy:
Ya X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Li H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Ge P; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Xu Y; Capital Medical University, Beijing, China.
Liu Z; Department of Biostatistics, Harvard School of Public Health, Boston, USA.
Zheng Z; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Mou S; University of Chinese Academy of Sciences, Beijing, China.
Liu C; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Zhang Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Wang R; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Zhang Q; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Ye X; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Wang W; Beijing Institute of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Zhang D; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Zhao J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Beijing Institute of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
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Źródło:
Aging and disease [Aging Dis] 2024 Feb 01; Vol. 15 (1), pp. 245-258. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*
Plaque, Atherosclerotic*
Immune System Diseases*
Humans ; T-Lymphocyte Subsets ; RNA
Czasopismo naukowe
Tytuł:
Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome in initiating ART among HIV-Infected patients in China-risk factors and management.
Autorzy:
Yang H; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China.
Liu Q; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China.
Wu Y; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China.
He K; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China.
Zeng Q; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China.
Liu M; Division of Infectious Diseases, Chongqing Public Health Medical Center, 109 Baoyu Road, Shapingba District, Chongqing, 400036, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Jan 02; Vol. 24 (1), pp. 5. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Reconstitution Inflammatory Syndrome*/epidemiology
Immune Reconstitution Inflammatory Syndrome*/etiology
HIV Infections*/complications
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Tuberculosis, Meningeal*/complications
Adult ; Humans ; Retrospective Studies ; Risk Factors ; China/epidemiology
Czasopismo naukowe
Tytuł:
Overcoming Resistance Mechanisms to Immune Checkpoint Inhibitors: Leveraging the Anti-Tumor Immune Response.
Autorzy:
Coschi CH; Department of Oncology, McMaster University, 699 Concession Street, Hamilton, ON L8V 5C2, Canada.
Juergens RA; Department of Oncology, McMaster University, 699 Concession Street, Hamilton, ON L8V 5C2, Canada.; Escarpment Cancer Research Institute, McMaster University, Hamilton, ON L8V 5C2, Canada.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2023 Dec 19; Vol. 31 (1), pp. 1-23. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immune Checkpoint Inhibitors*/pharmacology
Neoplasms*/drug therapy
Humans ; Immunity ; Biomarkers ; Tumor Microenvironment
Czasopismo naukowe

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