Temat: "INSULIN" - OpacWWW

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Insulin.

Insulin is a hormone produced by the pancreas. Insulin regulates blood glucose or blood sugar levels in the body of humans and many other mammals. A pancreas that fails to produce enough insulin is the cause of diabetes. Victims of diabetes are often prescribed periodic insulin injections to regulate their blood sugar, which reduces or eliminates their symptoms. They also may be required to obey a strict diet. Although diabetes is a manageable condition, it has no cure.

Salem Press Encyclopedia of Health, 2019. 2p.

Skocz do pozycji: 1 1.

Tytuł :: Integration of transcriptomics and metabolomics provides metabolic and functional insights into reduced insulin secretion in MIN6 β-cells exposed to deficient and excessive arginine.
Autorzy :: Xu L; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Lin X; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Li X; Institute of Animal Immune Engineering, Jiangsu Academy of Agricultural Sciences, Nanjing, P. R. China.
Hu Z; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Hou Q; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Wang Y; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Wang Z; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.; Pokaż więcej
Źródło :: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 Mar; Vol. 36 (3), pp. e22206.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Insulin Secretion*
Metabolome*
Transcriptome*
Arginine/*metabolism
Insulin-Secreting Cells/*metabolism
Animals ; Arginine/deficiency ; Arginine/pharmacology ; Cell Line, Tumor ; Insulin/metabolism ; Insulin-Secreting Cells/drug effects ; Mice
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Physiologic Insulin Resensitization as a Treatment Modality for Insulin Resistance Pathophysiology.
Autorzy :: Greenway F; Clinical Trials Unit, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA.
Loveridge B; Diabetes Relief, Layton, UT 84041, USA.
Grimes RM; Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030, USA.
Tucker TR; Department of Development and Cell Biology, University of California Irvine, Irvine, CA 92617, USA.
Alexander M; Department of Surgery, University of California Irvine, Orange, CA 92868, USA.
Hepford SA; Well Cell Global LLC, Houston, TX 77079, USA.
Fontenot J; Lafayette Arthritis and Endocrine Clinic, Lafayette, LA 70506, USA.
Nobles-James C; Division of Endocrinology, Mercer University School of Medicine, Macon, GA 31207, USA.
Wilson C; Well Cell Support LLC, Houston, TX 77079, USA.
Starr AM; Department of Orthopedic Surgery, Asheville Orthopedic Associates P.A, Asheville, NC 28801, USA.
Abdelsaid M; Biomedical Sciences Department, Mercer University School of Medicine, Savannah, GA 31404, USA.
Lewis ST; Eselle Health, Inc., La Jolla, CA 92037, USA.
Lakey JRT; Department of Surgery, University of California Irvine, Orange, CA 92868, USA.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 08; Vol. 23 (3). Date of Electronic Publication: 2022 Feb 08.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Insulin Resistance*
Diabetes Mellitus, Type 2/*drug therapy
Insulin, Regular, Human/*therapeutic use
Diabetes Mellitus, Type 2/metabolism ; Glycated Hemoglobin A/metabolism ; Humans ; Insulin Secretion/drug effects ; Insulin, Regular, Human/pharmacology ; Pancreas/drug effects ; Pancreas/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 3 3.

Tytuł :: 1α,25-(OH) 2 vitamin D 3 prevents insulin resistance and regulates coordinated exocytosis and insulin secretion.
Autorzy :: Mendes AKB; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Sulis PM; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Cavalari FC; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil; Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Padilla DPR; Universidad Nacional de Colombia, Departamento de Farmácia, Facultad de Ciencias, Bogotá, D. C., Colombia.
Aragón M; Universidad Nacional de Colombia, Departamento de Farmácia, Facultad de Ciencias, Bogotá, D. C., Colombia.
Gaspar JM; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Silva FRMB; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil; Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil. Electronic address: .; Pokaż więcej
Źródło :: The Journal of nutritional biochemistry [J Nutr Biochem] 2022 Jan; Vol. 99, pp. 108864. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Insulin Resistance*
Cholecalciferol/*analogs & derivatives
Exocytosis/*drug effects
Insulin/*metabolism
Insulin Secretion/*drug effects
Animals ; Calcium/metabolism ; Calcium Channels, L-Type/genetics ; Calcium Channels, L-Type/metabolism ; Cholecalciferol/metabolism ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Humans ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/drug effects ; Islets of Langerhans/metabolism ; Male ; Rats ; Rats, Wistar
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: The CLOCK protein regulates insulin secretion related with L-type calcium channels in rat pancreatic beta cells.
Autorzy :: Tian L; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China; Tianjin Children's Hospital, Tianjin, 300134, China.
Li X; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China.
Ding Y; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China; Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, 215028, China.
Li M; The Second People's Hospital of Changsha County, Hunan Province, 410129, China.
Tang Y; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China. Electronic address: .
Li D; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China. Electronic address: .; Pokaż więcej
Źródło :: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 22; Vol. 589, pp. 116-122. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Insulin Secretion*/genetics
CLOCK Proteins/*metabolism
Calcium Channels, L-Type/*metabolism
Insulin-Secreting Cells/*metabolism
Animals ; Base Sequence ; CLOCK Proteins/genetics ; Calcium/metabolism ; Calcium Channels, L-Type/genetics ; Down-Regulation/genetics ; Insulin/biosynthesis ; Male ; Promoter Regions, Genetic/genetics ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11).
Autorzy :: Zusi C; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Rinaldi E; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Bonetti S; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Boselli ML; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Trabetti E; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Verona, Italy.
Malerba G; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Verona, Italy.
Bonora E; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Bonadonna RC; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Division of Endocrinology and Metabolic Diseases, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Trombetta M; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy. .; Pokaż więcej
Źródło :: Journal of endocrinological investigation [J Endocrinol Invest] 2021 Dec; Vol. 44 (12), pp. 2567-2574. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :: Journal Article
MeSH Terms :: Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin*/biosynthesis
Insulin*/metabolism
Germinal Center Kinases/*genetics
Glucose/*metabolism
Glucose-6-Phosphatase/*genetics
Insulin Secretion/*genetics
Female ; Glucose-6-Phosphate/metabolism ; Haplotypes ; Humans ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Italy/epidemiology ; Male ; Middle Aged ; Polymorphism, Single Nucleotide
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes.
Autorzy :: Abels M; Lund University Diabetes Centre, Malmö, Sweden.
Riva M; Lund University Diabetes Centre, Malmö, Sweden.
Shcherbina L; Lund University Diabetes Centre, Malmö, Sweden.
Fischer AT; Lund University Diabetes Centre, Malmö, Sweden.
Banke E; Lund University Diabetes Centre, Malmö, Sweden.
Degerman E; Lund University Diabetes Centre, Malmö, Sweden.
Lindqvist A; Lund University Diabetes Centre, Malmö, Sweden.
Wierup N; Lund University Diabetes Centre, Malmö, Sweden. Electronic address: .; Pokaż więcej
Źródło :: Peptides [Peptides] 2022 May; Vol. 151, pp. 170747. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Diabetes Mellitus, Type 2*/metabolism
Hyperglycemia*/genetics
Hyperglycemia*/metabolism
Insulin Resistance*/genetics
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Animals ; Disease Models, Animal ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Insulin Secretion ; Mice ; Nerve Tissue Proteins/genetics ; Rats ; Streptozocin
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Contribution of Mitochondria to Insulin Secretion by Various Secretagogues.
Autorzy :: Ježek P; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Holendová B; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Jabůrek M; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Dlasková A; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Plecitá-Hlavatá L; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.; Pokaż więcej
Źródło :: Antioxidants & redox signaling [Antioxid Redox Signal] 2022 May; Vol. 36 (13-15), pp. 920-952. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Adenosine Triphosphate/metabolism ; Calcium/metabolism ; Glucose/metabolism ; Insulin/metabolism ; Insulin Secretion ; Mitochondria/metabolism ; NAD/metabolism ; NADP/metabolism ; Secretagogues/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity.
Autorzy :: Lee H; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Suh YS; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Changwon Hospital, Changwon, 51427, Korea.
Lee SI; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Cheon YH; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Kim M; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Noh HS; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Institute of Health Science, Gyeongsang National University Hospital, Jinju, 52727, Korea.
Kim HO; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Changwon Hospital, Changwon, 51427, Korea. .; Pokaż więcej
Źródło :: BMC research notes [BMC Res Notes] 2022 Apr 05; Vol. 15 (1), pp. 128. Date of Electronic Publication: 2022 Apr 05.
Typ publikacji :: Journal Article
MeSH Terms :: Arthritis, Rheumatoid*/metabolism
Insulin-Like Growth Factor I*/metabolism
C-Reactive Protein/metabolism ; Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Proteins/metabolism ; Interleukin-6
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 9 9.

Tytuł :: The effects of lycopene supplementation on insulin-like growth factor-1 and insulin-like growth factor binding proteins: A systematic review of randomized controlled trials.
Autorzy :: Meshkini F; Department of Biochemistry, School of medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.; Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ramezani-Jolfaie N; Department of Community Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Sargazi S; Cellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.
Clark CCT; Faculty Research Centre for Intelligent Healthcare, Coventry University, Coventry, UK.
Soltani S; Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.; Pokaż więcej
Źródło :: Phytotherapy research : PTR [Phytother Res] 2022 Apr; Vol. 36 (4), pp. 1633-1643. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji :: Journal Article; Review; Systematic Review
MeSH Terms :: Insulin-Like Growth Factor Binding Protein 3*/metabolism
Insulin-Like Growth Factor I*/metabolism
Dietary Supplements ; Insulin-Like Growth Factor Binding Proteins/metabolism ; Lycopene/pharmacology ; Randomized Controlled Trials as Topic
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Dynamic assessment of insulin secretion and insulin resistance in Asians with prediabetes.
Autorzy :: Magkos F; Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Lee MH; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lim M; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cook AR; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Chhay V; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Loh TP; Department of Laboratory Medicine, National University Hospital, Singapore.
Chia KS; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Baig S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ang IYH; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Tay JYY; NOVI Health, Singapore.
Khoo CM; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Medicine, National University Hospital, Singapore.
Halter JB; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Division of Geriatric and Palliative Medicine, University of Michigan, USA.
Toh SA; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; NOVI Health, Singapore; Department of Medicine, National University Hospital, Singapore; Regional Health System Office, National University Health System, Singapore; Singapore Population HEalth ImpRovement Centre (SPHERiC), National University Health System, Singapore. Electronic address: .; Pokaż więcej
Źródło :: Metabolism: clinical and experimental [Metabolism] 2022 Mar; Vol. 128, pp. 154957. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Insulin Resistance*
Insulin Secretion*
Prediabetic State/*metabolism
Adult ; Asians ; C-Peptide/analysis ; Female ; Glucose Tolerance Test ; Humans ; Insulin-Secreting Cells/physiology ; Male ; Middle Aged ; Prediabetic State/ethnology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor.
Autorzy :: Peng J; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ramatchandirin B; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang Y; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Pearah A; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Namachivayam K; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wolf RM; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Steele K; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
MohanKumar K; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yu L; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Guo S; Department of Nutrition and Food Science, Texas A&M University, College Station, Texas, USA.
White MF; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.
Maheshwari A; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
He L; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: .; Pokaż więcej
Źródło :: The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101621. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Benzoates*/pharmacology
Enzyme Inhibitors*/pharmacology
Insulin Receptor Substrate Proteins*/genetics
Insulin Receptor Substrate Proteins*/metabolism
Nitrobenzenes*/pharmacology
Pyrazolones*/pharmacology
Receptor, Insulin*/metabolism
p300-CBP Transcription Factors*/antagonists & inhibitors
p300-CBP Transcription Factors*/metabolism
Humans ; Insulin/metabolism ; Phosphorylation ; Tyrosine/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: Effect of artemisinin on improving islet function in rats fed with maternal high-fat diet.
Autorzy :: Chen Y; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Fan ZQ; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Guo JC; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Men K; Department of Laboratory, The Second Hospital of Tianjin Medical University, Tianjin, PR China.; Pokaż więcej
Źródło :: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2022 May; Vol. 38 (5), pp. 416-424. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :: Journal Article
MeSH Terms :: Artemisinins*/metabolism
Artemisinins*/pharmacology
Insulin Resistance*/physiology
Insulin-Secreting Cells*/metabolism
Animals ; Blood Glucose/metabolism ; Diet, High-Fat/adverse effects ; Female ; Glucose/pharmacology ; Humans ; Insulin/metabolism ; Pregnancy ; Rats
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity.
Autorzy :: Flisher MF; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States.
Shin D; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States.
Huising MO; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, United States. Electronic address: .; Pokaż więcej
Źródło :: Peptides [Peptides] 2022 May; Vol. 151, pp. 170748. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :: Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Corticotropin-Releasing Hormone/*metabolism
Somatostatin/*metabolism
Urocortins/*metabolism
Animals ; Humans ; Insulin/metabolism ; Insulin Secretion ; Mice ; Somatostatin/genetics ; Urocortins/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease.
Autorzy :: Takahashi SI; Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo, Japan.
Perks CM; Department of Translational Health Sciences, University of Bristol, Bristol, United Kingdom.; Pokaż więcej
Źródło :: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Apr 21; Vol. 13, pp. 892140. Date of Electronic Publication: 2022 Apr 21 (Print Publication: 2022).
Typ publikacji :: Editorial
MeSH Terms :: Insulin*
Insulin-Like Growth Factor Binding Proteins*
Insulin-Like Growth Factor II
: Opinia redakcyjna

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
Autorzy :: Matsushita M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Awazawa M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan. Electronic address: .
Kobayashi N; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Ikushima YM; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Soeda K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Tamura-Nakano M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Muratani M; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Kobayashi K; Section of Viral Vector Development, National Institute for Physiological Sciences, Hojozaka 27, Myodaiji, Okazaki, Aichi 305-8575, Japan.
Blüher M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig, Leipzig, Germany; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München, University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
Brüning JC; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann Strasse 26, 50931 Cologne, Germany; National Center for Diabetes Research (DZD), Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
Ueki K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan; Department of Molecular Diabetology, Graduate School of Medicine, The University of Tokyo, 3-7-1 Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan. Electronic address: .; Pokaż więcej
Źródło :: Cell chemical biology [Cell Chem Biol] 2022 Apr 21; Vol. 29 (4), pp. 680-689.e6. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :: Journal Article
MeSH Terms :: Insulin Resistance*/genetics
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/metabolism
Animals ; Insulin/metabolism ; Insulin Receptor Substrate Proteins/genetics ; Insulin Receptor Substrate Proteins/metabolism ; Liver/metabolism ; Mice ; Mice, Inbred C57BL ; Obesity/complications ; Obesity/genetics ; PPAR gamma/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Oral Glucose Tolerance Test-based Measures of Insulin Secretory Response in Pregnancy.
Autorzy :: Powe CE; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Locascio JJ; Harvard Medical School, Boston, MA, USA.; Harvard Catalyst Biostatistics Consulting Unit, Boston, MA, USA.; Alzheimer's Disease Research Center, Neurology Department, Massachusetts General Hospital, Boston, MA, USA.
Gordesky LH; Department of Reproductive Biology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA.
Florez JC; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Catalano PM; Mother Infant Research Institute, Department of Obstetrics and Gynecology, Tufts University School of Medicine, Friedman School of Nutrition Science and Policy, Boston, MA, USA.; Pokaż więcej
Źródło :: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2022 Apr 19; Vol. 107 (5), pp. e1871-e1878.
Typ publikacji :: Journal Article
MeSH Terms :: Blood Glucose*/analysis
Insulin Resistance*/physiology
Female ; Glucose Tolerance Test ; Humans ; Insulin/metabolism ; Insulin Secretion ; Longitudinal Studies ; Pregnancy
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene.
Autorzy :: Abu Helal R; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Muturi HT; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Lee AD; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; School of Exercise and Rehabilitation Sciences, College of Health and Human Services, University of Toledo, Toledo, OH 43606, USA.
Li W; Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV 25755, USA.
Ghadieh HE; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; Department of Biomedical Sciences, Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura P.O. Box 100, Lebanon.
Najjar SM; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 14; Vol. 23 (8). Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :: Journal Article
MeSH Terms :: Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Hypercholesterolemia*/genetics
Hypercholesterolemia*/metabolism
Insulin Resistance*/genetics
Plaque, Atherosclerotic*/genetics
Plaque, Atherosclerotic*/metabolism
Animals ; Carcinoembryonic Antigen ; Endothelial Cells/metabolism ; Fibrosis ; Inflammation/metabolism ; Insulin/metabolism ; Insulin, Regular, Human ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 18 18.

Tytuł :: Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism.
Autorzy :: Crespo-Masip M; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.
Perez-Gomez A; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.
Garcia-Carrasco A; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Jover R; Experimental Hepatology Unit, IIS Hospital La Fe, 46026 Valencia, Spain.; Research Network Center for Liver and Digestive Diseases (CIBERehd), 28029 Madrid, Spain.; Biochemistry and Molecular Biology Department, University of Valencia, 46100 Valencia, Spain.
Guzmán C; Experimental Hepatology Unit, IIS Hospital La Fe, 46026 Valencia, Spain.; Research Network Center for Liver and Digestive Diseases (CIBERehd), 28029 Madrid, Spain.; Biochemistry and Molecular Biology Department, University of Valencia, 46100 Valencia, Spain.
Dolcet X; Oncological Pathology Research Group, IRBLleida, 25198 Lleida, Spain.
Ibarz M; Indicators and Specifications of the Quality in the Clinical Laboratory Group, IRBLleida, 25198 Lleida, Spain.
Martínez C; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Eritja À; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Diaz-Tocados JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Valdivielso JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.; Pokaż więcej
Źródło :: Nutrients [Nutrients] 2022 Apr 05; Vol. 14 (7). Date of Electronic Publication: 2022 Apr 05.
Typ publikacji :: Journal Article
MeSH Terms :: Hypoglycemia*
Insulin Resistance*
Vitamin D Deficiency*/complications
Vitamin D Deficiency*/metabolism
Animals ; Humans ; Insulin/metabolism ; Lipid Metabolism ; Mice ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Receptor, Insulin/genetics ; Receptor, Insulin/metabolism ; Vitamin D/metabolism ; Vitamins
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation.
Autorzy :: Jiang Y; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Zhu H; Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Chen Z; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Yu YC; Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Guo XH; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Chen Y; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Yang MM; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Chen BW; Department of Obstetrics, Ninghai Maternal and Child Health Hospital, Ningbo, China.
Sagnelli M; University of Connecticut School of Medicine, Farmington, CT, United States.
Xu D; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Zhao BH; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Luo Q; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.; Pokaż więcej
Źródło :: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Apr 01; Vol. 13, pp. 844707. Date of Electronic Publication: 2022 Apr 01 (Print Publication: 2022).
Typ publikacji :: Journal Article
MeSH Terms :: Diabetes Mellitus, Type 2*
Diabetes, Gestational*/genetics
Glucose Intolerance*/genetics
Insulin Resistance*/genetics
Adult ; Animals ; Epigenesis, Genetic ; Female ; Forkhead Box Protein O1/genetics ; Humans ; Insulin ; Insulin-Like Growth Factor II/genetics ; Liver ; Male ; Mice ; Pregnancy
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.
Autorzy :: Rahim M; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Banerjee DR; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Overway EM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Bosma KJ; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Rosch JC; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Oeser JK; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Wang B; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurology, Vanderbilt University, Nashville, Tennessee, USA.
Jacobson DA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
O'Brien RM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Young JD; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA. Electronic address: .; Pokaż więcej
Źródło :: The Journal of biological chemistry [J Biol Chem] 2022 Apr; Vol. 298 (4), pp. 101729. Date of Electronic Publication: 2022 Feb 15.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Glucose*/metabolism
Glucose-6-Phosphatase*/genetics
Glucose-6-Phosphatase*/metabolism
Insulin-Secreting Cells*/enzymology
Animals ; Blood Glucose/metabolism ; Genome-Wide Association Study ; Insulin/metabolism ; Insulin Secretion ; Mice ; Mice, Knockout ; Oxidation-Reduction
: Czasopismo naukowe

Szczegóły

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