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Wyszukujesz frazę ""INSULIN"" wg kryterium: Temat


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Tytuł :
Integration of transcriptomics and metabolomics provides metabolic and functional insights into reduced insulin secretion in MIN6 β-cells exposed to deficient and excessive arginine.
Autorzy :
Xu L; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Lin X; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Li X; Institute of Animal Immune Engineering, Jiangsu Academy of Agricultural Sciences, Nanjing, P. R. China.
Hu Z; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Hou Q; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Wang Y; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
Wang Z; College of Animal Science and Technology, Shandong Agricultural University, Taian, P. R. China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 Mar; Vol. 36 (3), pp. e22206.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Secretion*
Metabolome*
Transcriptome*
Arginine/*metabolism
Insulin-Secreting Cells/*metabolism
Animals ; Arginine/deficiency ; Arginine/pharmacology ; Cell Line, Tumor ; Insulin/metabolism ; Insulin-Secreting Cells/drug effects ; Mice
Czasopismo naukowe
Tytuł :
Physiologic Insulin Resensitization as a Treatment Modality for Insulin Resistance Pathophysiology.
Autorzy :
Greenway F; Clinical Trials Unit, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA.
Loveridge B; Diabetes Relief, Layton, UT 84041, USA.
Grimes RM; Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030, USA.
Tucker TR; Department of Development and Cell Biology, University of California Irvine, Irvine, CA 92617, USA.
Alexander M; Department of Surgery, University of California Irvine, Orange, CA 92868, USA.
Hepford SA; Well Cell Global LLC, Houston, TX 77079, USA.
Fontenot J; Lafayette Arthritis and Endocrine Clinic, Lafayette, LA 70506, USA.
Nobles-James C; Division of Endocrinology, Mercer University School of Medicine, Macon, GA 31207, USA.
Wilson C; Well Cell Support LLC, Houston, TX 77079, USA.
Starr AM; Department of Orthopedic Surgery, Asheville Orthopedic Associates P.A, Asheville, NC 28801, USA.
Abdelsaid M; Biomedical Sciences Department, Mercer University School of Medicine, Savannah, GA 31404, USA.
Lewis ST; Eselle Health, Inc., La Jolla, CA 92037, USA.
Lakey JRT; Department of Surgery, University of California Irvine, Orange, CA 92868, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 08; Vol. 23 (3). Date of Electronic Publication: 2022 Feb 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Insulin Resistance*
Diabetes Mellitus, Type 2/*drug therapy
Insulin, Regular, Human/*therapeutic use
Diabetes Mellitus, Type 2/metabolism ; Glycated Hemoglobin A/metabolism ; Humans ; Insulin Secretion/drug effects ; Insulin, Regular, Human/pharmacology ; Pancreas/drug effects ; Pancreas/metabolism
Czasopismo naukowe
Tytuł :
1α,25-(OH) 2 vitamin D 3 prevents insulin resistance and regulates coordinated exocytosis and insulin secretion.
Autorzy :
Mendes AKB; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Sulis PM; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Cavalari FC; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil; Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Padilla DPR; Universidad Nacional de Colombia, Departamento de Farmácia, Facultad de Ciencias, Bogotá, D. C., Colombia.
Aragón M; Universidad Nacional de Colombia, Departamento de Farmácia, Facultad de Ciencias, Bogotá, D. C., Colombia.
Gaspar JM; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil.
Silva FRMB; Departamento de Bioquímica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil; Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis- SC, Brazil. Electronic address: .
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2022 Jan; Vol. 99, pp. 108864. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Cholecalciferol/*analogs & derivatives
Exocytosis/*drug effects
Insulin/*metabolism
Insulin Secretion/*drug effects
Animals ; Calcium/metabolism ; Calcium Channels, L-Type/genetics ; Calcium Channels, L-Type/metabolism ; Cholecalciferol/metabolism ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Humans ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/drug effects ; Islets of Langerhans/metabolism ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The CLOCK protein regulates insulin secretion related with L-type calcium channels in rat pancreatic beta cells.
Autorzy :
Tian L; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China; Tianjin Children's Hospital, Tianjin, 300134, China.
Li X; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China.
Ding Y; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China; Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, 215028, China.
Li M; The Second People's Hospital of Changsha County, Hunan Province, 410129, China.
Tang Y; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China. Electronic address: .
Li D; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 22; Vol. 589, pp. 116-122. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Secretion*/genetics
CLOCK Proteins/*metabolism
Calcium Channels, L-Type/*metabolism
Insulin-Secreting Cells/*metabolism
Animals ; Base Sequence ; CLOCK Proteins/genetics ; Calcium/metabolism ; Calcium Channels, L-Type/genetics ; Down-Regulation/genetics ; Insulin/biosynthesis ; Male ; Promoter Regions, Genetic/genetics ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11).
Autorzy :
Zusi C; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Rinaldi E; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Bonetti S; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Boselli ML; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Trabetti E; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Verona, Italy.
Malerba G; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Verona, Italy.
Bonora E; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy.
Bonadonna RC; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Division of Endocrinology and Metabolic Diseases, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Trombetta M; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Hospital Trust of Verona, Piazzale Stefani 1, 37126, Verona, Italy. .
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Źródło :
Journal of endocrinological investigation [J Endocrinol Invest] 2021 Dec; Vol. 44 (12), pp. 2567-2574. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin*/biosynthesis
Insulin*/metabolism
Germinal Center Kinases/*genetics
Glucose/*metabolism
Glucose-6-Phosphatase/*genetics
Insulin Secretion/*genetics
Female ; Glucose-6-Phosphate/metabolism ; Haplotypes ; Humans ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Italy/epidemiology ; Male ; Middle Aged ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes.
Autorzy :
Abels M; Lund University Diabetes Centre, Malmö, Sweden.
Riva M; Lund University Diabetes Centre, Malmö, Sweden.
Shcherbina L; Lund University Diabetes Centre, Malmö, Sweden.
Fischer AT; Lund University Diabetes Centre, Malmö, Sweden.
Banke E; Lund University Diabetes Centre, Malmö, Sweden.
Degerman E; Lund University Diabetes Centre, Malmö, Sweden.
Lindqvist A; Lund University Diabetes Centre, Malmö, Sweden.
Wierup N; Lund University Diabetes Centre, Malmö, Sweden. Electronic address: .
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Źródło :
Peptides [Peptides] 2022 May; Vol. 151, pp. 170747. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2*/metabolism
Hyperglycemia*/genetics
Hyperglycemia*/metabolism
Insulin Resistance*/genetics
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Animals ; Disease Models, Animal ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Insulin Secretion ; Mice ; Nerve Tissue Proteins/genetics ; Rats ; Streptozocin
Czasopismo naukowe
Tytuł :
Contribution of Mitochondria to Insulin Secretion by Various Secretagogues.
Autorzy :
Ježek P; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Holendová B; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Jabůrek M; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Dlasková A; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Plecitá-Hlavatá L; Department of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
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Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2022 May; Vol. 36 (13-15), pp. 920-952. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Adenosine Triphosphate/metabolism ; Calcium/metabolism ; Glucose/metabolism ; Insulin/metabolism ; Insulin Secretion ; Mitochondria/metabolism ; NAD/metabolism ; NADP/metabolism ; Secretagogues/metabolism
Czasopismo naukowe
Tytuł :
Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity.
Autorzy :
Lee H; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Suh YS; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Changwon Hospital, Changwon, 51427, Korea.
Lee SI; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Cheon YH; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Kim M; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Hospital, Jinju, 52727, Korea.
Noh HS; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Institute of Health Science, Gyeongsang National University Hospital, Jinju, 52727, Korea.
Kim HO; Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine and Changwon Hospital, Changwon, 51427, Korea. .
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Źródło :
BMC research notes [BMC Res Notes] 2022 Apr 05; Vol. 15 (1), pp. 128. Date of Electronic Publication: 2022 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Arthritis, Rheumatoid*/metabolism
Insulin-Like Growth Factor I*/metabolism
C-Reactive Protein/metabolism ; Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor Binding Proteins/metabolism ; Interleukin-6
Czasopismo naukowe
Tytuł :
The effects of lycopene supplementation on insulin-like growth factor-1 and insulin-like growth factor binding proteins: A systematic review of randomized controlled trials.
Autorzy :
Meshkini F; Department of Biochemistry, School of medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.; Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ramezani-Jolfaie N; Department of Community Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Sargazi S; Cellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.
Clark CCT; Faculty Research Centre for Intelligent Healthcare, Coventry University, Coventry, UK.
Soltani S; Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2022 Apr; Vol. 36 (4), pp. 1633-1643. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Insulin-Like Growth Factor Binding Protein 3*/metabolism
Insulin-Like Growth Factor I*/metabolism
Dietary Supplements ; Insulin-Like Growth Factor Binding Proteins/metabolism ; Lycopene/pharmacology ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Dynamic assessment of insulin secretion and insulin resistance in Asians with prediabetes.
Autorzy :
Magkos F; Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Lee MH; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lim M; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cook AR; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Chhay V; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Loh TP; Department of Laboratory Medicine, National University Hospital, Singapore.
Chia KS; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Baig S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ang IYH; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Tay JYY; NOVI Health, Singapore.
Khoo CM; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Medicine, National University Hospital, Singapore.
Halter JB; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Division of Geriatric and Palliative Medicine, University of Michigan, USA.
Toh SA; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; NOVI Health, Singapore; Department of Medicine, National University Hospital, Singapore; Regional Health System Office, National University Health System, Singapore; Singapore Population HEalth ImpRovement Centre (SPHERiC), National University Health System, Singapore. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2022 Mar; Vol. 128, pp. 154957. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Insulin Secretion*
Prediabetic State/*metabolism
Adult ; Asians ; C-Peptide/analysis ; Female ; Glucose Tolerance Test ; Humans ; Insulin-Secreting Cells/physiology ; Male ; Middle Aged ; Prediabetic State/ethnology
Czasopismo naukowe
Tytuł :
The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor.
Autorzy :
Peng J; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ramatchandirin B; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang Y; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Pearah A; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Namachivayam K; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wolf RM; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Steele K; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
MohanKumar K; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yu L; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Guo S; Department of Nutrition and Food Science, Texas A&M University, College Station, Texas, USA.
White MF; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.
Maheshwari A; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
He L; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101621. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Benzoates*/pharmacology
Enzyme Inhibitors*/pharmacology
Insulin Receptor Substrate Proteins*/genetics
Insulin Receptor Substrate Proteins*/metabolism
Nitrobenzenes*/pharmacology
Pyrazolones*/pharmacology
Receptor, Insulin*/metabolism
p300-CBP Transcription Factors*/antagonists & inhibitors
p300-CBP Transcription Factors*/metabolism
Humans ; Insulin/metabolism ; Phosphorylation ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł :
Effect of artemisinin on improving islet function in rats fed with maternal high-fat diet.
Autorzy :
Chen Y; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Fan ZQ; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Guo JC; Department of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
Men K; Department of Laboratory, The Second Hospital of Tianjin Medical University, Tianjin, PR China.
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Źródło :
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2022 May; Vol. 38 (5), pp. 416-424. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Artemisinins*/metabolism
Artemisinins*/pharmacology
Insulin Resistance*/physiology
Insulin-Secreting Cells*/metabolism
Animals ; Blood Glucose/metabolism ; Diet, High-Fat/adverse effects ; Female ; Glucose/pharmacology ; Humans ; Insulin/metabolism ; Pregnancy ; Rats
Czasopismo naukowe
Tytuł :
Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity.
Autorzy :
Flisher MF; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States.
Shin D; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States.
Huising MO; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, CA, United States; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, United States. Electronic address: .
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Źródło :
Peptides [Peptides] 2022 May; Vol. 151, pp. 170748. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Corticotropin-Releasing Hormone/*metabolism
Somatostatin/*metabolism
Urocortins/*metabolism
Animals ; Humans ; Insulin/metabolism ; Insulin Secretion ; Mice ; Somatostatin/genetics ; Urocortins/genetics
Czasopismo naukowe
Tytuł :
Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease.
Autorzy :
Takahashi SI; Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo, Japan.
Perks CM; Department of Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Apr 21; Vol. 13, pp. 892140. Date of Electronic Publication: 2022 Apr 21 (Print Publication: 2022).
Typ publikacji :
Editorial
MeSH Terms :
Insulin*
Insulin-Like Growth Factor Binding Proteins*
Insulin-Like Growth Factor II
Opinia redakcyjna
Tytuł :
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
Autorzy :
Matsushita M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Awazawa M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan. Electronic address: .
Kobayashi N; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Ikushima YM; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Soeda K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Tamura-Nakano M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.
Muratani M; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Kobayashi K; Section of Viral Vector Development, National Institute for Physiological Sciences, Hojozaka 27, Myodaiji, Okazaki, Aichi 305-8575, Japan.
Blüher M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig, Leipzig, Germany; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München, University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
Brüning JC; Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann Strasse 26, 50931 Cologne, Germany; National Center for Diabetes Research (DZD), Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
Ueki K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan; Department of Molecular Diabetology, Graduate School of Medicine, The University of Tokyo, 3-7-1 Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan. Electronic address: .
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Źródło :
Cell chemical biology [Cell Chem Biol] 2022 Apr 21; Vol. 29 (4), pp. 680-689.e6. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*/genetics
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/metabolism
Animals ; Insulin/metabolism ; Insulin Receptor Substrate Proteins/genetics ; Insulin Receptor Substrate Proteins/metabolism ; Liver/metabolism ; Mice ; Mice, Inbred C57BL ; Obesity/complications ; Obesity/genetics ; PPAR gamma/genetics
Czasopismo naukowe
Tytuł :
Oral Glucose Tolerance Test-based Measures of Insulin Secretory Response in Pregnancy.
Autorzy :
Powe CE; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Locascio JJ; Harvard Medical School, Boston, MA, USA.; Harvard Catalyst Biostatistics Consulting Unit, Boston, MA, USA.; Alzheimer's Disease Research Center, Neurology Department, Massachusetts General Hospital, Boston, MA, USA.
Gordesky LH; Department of Reproductive Biology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA.
Florez JC; Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Catalano PM; Mother Infant Research Institute, Department of Obstetrics and Gynecology, Tufts University School of Medicine, Friedman School of Nutrition Science and Policy, Boston, MA, USA.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2022 Apr 19; Vol. 107 (5), pp. e1871-e1878.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose*/analysis
Insulin Resistance*/physiology
Female ; Glucose Tolerance Test ; Humans ; Insulin/metabolism ; Insulin Secretion ; Longitudinal Studies ; Pregnancy
Czasopismo naukowe
Tytuł :
Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene.
Autorzy :
Abu Helal R; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Muturi HT; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Lee AD; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; School of Exercise and Rehabilitation Sciences, College of Health and Human Services, University of Toledo, Toledo, OH 43606, USA.
Li W; Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV 25755, USA.
Ghadieh HE; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; Department of Biomedical Sciences, Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura P.O. Box 100, Lebanon.
Najjar SM; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.; Center for Diabetes and Endocrine Research, College of Medicine, University of Toledo, Toledo, OH 43606, USA.; Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 14; Vol. 23 (8). Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Hypercholesterolemia*/genetics
Hypercholesterolemia*/metabolism
Insulin Resistance*/genetics
Plaque, Atherosclerotic*/genetics
Plaque, Atherosclerotic*/metabolism
Animals ; Carcinoembryonic Antigen ; Endothelial Cells/metabolism ; Fibrosis ; Inflammation/metabolism ; Insulin/metabolism ; Insulin, Regular, Human ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/metabolism
Czasopismo naukowe
Tytuł :
Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism.
Autorzy :
Crespo-Masip M; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.
Perez-Gomez A; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.
Garcia-Carrasco A; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Jover R; Experimental Hepatology Unit, IIS Hospital La Fe, 46026 Valencia, Spain.; Research Network Center for Liver and Digestive Diseases (CIBERehd), 28029 Madrid, Spain.; Biochemistry and Molecular Biology Department, University of Valencia, 46100 Valencia, Spain.
Guzmán C; Experimental Hepatology Unit, IIS Hospital La Fe, 46026 Valencia, Spain.; Research Network Center for Liver and Digestive Diseases (CIBERehd), 28029 Madrid, Spain.; Biochemistry and Molecular Biology Department, University of Valencia, 46100 Valencia, Spain.
Dolcet X; Oncological Pathology Research Group, IRBLleida, 25198 Lleida, Spain.
Ibarz M; Indicators and Specifications of the Quality in the Clinical Laboratory Group, IRBLleida, 25198 Lleida, Spain.
Martínez C; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Eritja À; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Diaz-Tocados JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.
Valdivielso JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), 25198 Lleida, Spain.; Medicine Department, University of Lleida, 25198 Lleida, Spain.
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Źródło :
Nutrients [Nutrients] 2022 Apr 05; Vol. 14 (7). Date of Electronic Publication: 2022 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Hypoglycemia*
Insulin Resistance*
Vitamin D Deficiency*/complications
Vitamin D Deficiency*/metabolism
Animals ; Humans ; Insulin/metabolism ; Lipid Metabolism ; Mice ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Receptor, Insulin/genetics ; Receptor, Insulin/metabolism ; Vitamin D/metabolism ; Vitamins
Czasopismo naukowe
Tytuł :
Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation.
Autorzy :
Jiang Y; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Zhu H; Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Chen Z; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Yu YC; Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Guo XH; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Chen Y; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Yang MM; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Chen BW; Department of Obstetrics, Ninghai Maternal and Child Health Hospital, Ningbo, China.
Sagnelli M; University of Connecticut School of Medicine, Farmington, CT, United States.
Xu D; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Zhao BH; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Luo Q; Department of Obstetrics, Women's Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Apr 01; Vol. 13, pp. 844707. Date of Electronic Publication: 2022 Apr 01 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*
Diabetes, Gestational*/genetics
Glucose Intolerance*/genetics
Insulin Resistance*/genetics
Adult ; Animals ; Epigenesis, Genetic ; Female ; Forkhead Box Protein O1/genetics ; Humans ; Insulin ; Insulin-Like Growth Factor II/genetics ; Liver ; Male ; Mice ; Pregnancy
Czasopismo naukowe
Tytuł :
Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.
Autorzy :
Rahim M; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Banerjee DR; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Overway EM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Bosma KJ; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Rosch JC; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Oeser JK; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Wang B; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Neurology, Vanderbilt University, Nashville, Tennessee, USA.
Jacobson DA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
O'Brien RM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Young JD; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Apr; Vol. 298 (4), pp. 101729. Date of Electronic Publication: 2022 Feb 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Glucose*/metabolism
Glucose-6-Phosphatase*/genetics
Glucose-6-Phosphatase*/metabolism
Insulin-Secreting Cells*/enzymology
Animals ; Blood Glucose/metabolism ; Genome-Wide Association Study ; Insulin/metabolism ; Insulin Secretion ; Mice ; Mice, Knockout ; Oxidation-Reduction
Czasopismo naukowe

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