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Tytuł:
Baseline determinants of remission of type 2 diabetes in response to short-term insulin-based therapy: The pivotal role of beta-cell function.
Autorzy:
Retnakaran R; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Pu J; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.
Emery A; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.
Kramer CK; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada.
Zinman B; Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2023 Sep; Vol. 25 (9), pp. 2473-2481. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Adult ; Humans ; Insulin/therapeutic use ; Insulin Glargine/therapeutic use ; Glycated Hemoglobin ; Blood Glucose/analysis ; Insulin, Regular, Human
Czasopismo naukowe
Szczegóły
Tytuł:
Syndrome of Congenital Insulin Resistance Caused by a Novel INSR Gene Mutation
Autorzy:
Rojek A; Poznan University of Medical Sciences, Institute of Pediatrics, Department of Pediatric Endocrinology and Rheumatology, Poznan, Poland
Wikiera B; Wroclaw Medical University, Department of Endocrinology and Diabetology for Children and Adolescents, Wroclaw, Poland
Noczynska A; Wroclaw Medical University, Department of Endocrinology and Diabetology for Children and Adolescents, Wroclaw, Poland
Niedziela M; Poznan University of Medical Sciences, Institute of Pediatrics, Department of Pediatric Endocrinology and Rheumatology; Karol Jonscher’s Clinical Hospital, Poznan, Poland
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Źródło:
Journal of clinical research in pediatric endocrinology [J Clin Res Pediatr Endocrinol] 2023 Aug 23; Vol. 15 (3), pp. 312-317. Date of Electronic Publication: 2021 Dec 30.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Antigens, CD*/genetics
Cardiomyopathy, Hypertrophic*/complications
Diabetes Mellitus*
Donohue Syndrome*/diagnosis
Donohue Syndrome*/genetics
Hyperglycemia*/complications
Hypertrichosis*/complications
Hypoglycemia*/complications
Insulin Resistance*/genetics
Receptor, Insulin*/genetics
Female ; Humans ; Infant ; Infant, Newborn ; Male ; Facies ; Insulin ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice.
Autorzy:
Mathew D; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA.; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA.
Barillas-Cerritos J; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA.; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA.; Pediatric Endocrinology, Metabolism and Diabetes, Winthrop Pediatrics Associates, Mineola, NY, USA.
Nedeljkovic-Kurepa A; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA.; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA.
Abraham M; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA.; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA.
Taylor MD; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA.; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA.; Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Deutschman CS; Department of Pediatrics, Cohen Children's Medical Center, Lake Success, NY, USA. .; Institute for Molecular Medicine, Feinstein Institutes for Medical Research, Room 3140, 350 Community Dr, Manhasset, NY, 11030, USA. .; Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2023 Aug 07; Vol. 29 (1), pp. 106. Date of Electronic Publication: 2023 Aug 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Receptor, Insulin*/metabolism
Sepsis*/metabolism
Insulin Receptor Substrate Proteins*/metabolism
Animals ; Mice ; Glucose/metabolism ; Insulin/metabolism ; Mice, Inbred C57BL ; Muscle, Skeletal/metabolism ; Phosphorylation ; Punctures ; Tyrosine/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Insulin: Know what your immunoassay detects. Evaluation of two new immunoassays.
Autorzy:
Violin A; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France. Electronic address: .
Enard E; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France.
Blin J; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France; Nantes Université, CHU Nantes, INSERM U1235, The Enteric Nervous System in Gut and Brain Disorders, IMAD, F-44000 Nantes, France.
Paillusson D; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France.
Collin A; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France.
Guénet D; Normandie Univ, UNICAEN, CHU of Caen Normandie, Laboratory of Biochemistry, 14000 Caen, France.
Raverot V; Service de Biochimie et Biologie Moléculaire, Laboratoire de Biologie Médicale Multi-Sites (LBMMS), Hospices Civils de Lyon, Lyon, France.
Bach-Ngohou K; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France; Nantes Université, CHU Nantes, INSERM U1235, The Enteric Nervous System in Gut and Brain Disorders, IMAD, F-44000 Nantes, France.
Masson D; Nantes Université, CHU Nantes, Department of Biology, Laboratory of Biochemistry, F-44000 Nantes, France; Nantes Université, CHU Nantes, INSERM U1235, The Enteric Nervous System in Gut and Brain Disorders, IMAD, F-44000 Nantes, France.
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Źródło:
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2023 Aug 01; Vol. 548, pp. 117516. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Insulin*/blood
Insulin Secretion*
Humans ; Hypoglycemia/blood ; Immunoassay ; Insulin-Secreting Cells
Czasopismo naukowe
Szczegóły
Tytuł:
Hepatic insulin receptor: new views on the mechanisms of liver disease.
Autorzy:
Lee WH; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, USA.
Najjar SM; Department of Biomedical Sciences and the Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA.
Kahn CR; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.
Hinds TD Jr; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, USA; Barnstable Brown Diabetes Center, University of Kentucky College of Medicine, Lexington, KY, USA; Markey Cancer Center, University of Kentucky, Lexington, KY, USA. Electronic address: .
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Źródło:
Metabolism: clinical and experimental [Metabolism] 2023 Aug; Vol. 145, pp. 155607. Date of Electronic Publication: 2023 Jun 02.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Insulin Resistance*
Non-alcoholic Fatty Liver Disease*/metabolism
Humans ; Receptor, Insulin ; Liver/metabolism ; Liver Cirrhosis/pathology ; Insulin
Czasopismo naukowe
Szczegóły
Tytuł:
The role of peripheral β-amyloid in insulin resistance, insulin secretion, and prediabetes: in vitro and population-based studies.
Autorzy:
Xu Z; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Chen J; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Wang P; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Li L; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Hu S; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Liu H; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Huang Y; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Mo X; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Yan H; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Shan Z; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Wang D; Xiangyang Key Laboratory of Public Health and Epidemic Prevention Materials Research, Xiangyang Public Inspection and Testing Center, Xiangyang, China.
Xu J; Department of Elderly Health Management, Shenzhen Center for Chronic Disease Control, Shenzhen, China.
Liu L; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Peng X; Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2023 Jul 19; Vol. 14, pp. 1195658. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Prediabetic State*
Humans ; Animals ; Mice ; Amyloid beta-Peptides/metabolism ; Case-Control Studies ; Insulin Secretion ; Prospective Studies ; Insulin/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy.
Autorzy:
Thoduvayil S; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Weerakkody JS; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Sundaram RVK; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Topper M; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA.
Bera M; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Coleman J; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Li X; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Mariappan M; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520 USA.
Ramakrishnan S; Nanobiology Institute, Yale University School of Medicine, West Haven, CT, 06516 USA; Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520 USA. Electronic address: .
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Źródło:
Cell calcium [Cell Calcium] 2023 Jul; Vol. 113, pp. 102766. Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Insulin/pharmacology ; Insulin/metabolism ; Insulin Secretion ; Exocytosis/physiology ; Glucose/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Assessment of circulating insulin using liquid chromatography-mass spectrometry during insulin glargine treatment in type 2 diabetes: Implications for estimating insulin sensitivity and β-cell function.
Autorzy:
Seegmiller JC; Department of Laboratory Medicine, Advanced Research and Diagnostic Laboratory, University of Minnesota, Minneapolis, Minnesota, USA.
Schmit DJ; Department of Laboratory Medicine, Advanced Research and Diagnostic Laboratory, University of Minnesota, Minneapolis, Minnesota, USA.
Arends VL; Department of Laboratory Medicine, Advanced Research and Diagnostic Laboratory, University of Minnesota, Minneapolis, Minnesota, USA.
Steffes MW; Department of Laboratory Medicine, Advanced Research and Diagnostic Laboratory, University of Minnesota, Minneapolis, Minnesota, USA.
Kahn SE; Division of Metabolism, Endocrinology and Nutrition, VA Puget Sound Health Care System and University of Washington, Seattle, Washington, USA.
Younes N; The Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Rockville, Maryland, USA.
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Corporate Authors:
GRADE Research Group
Źródło:
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2023 Jul; Vol. 25 (7), pp. 1995-2004. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*
Insulin Resistance*
Humans ; Insulin Glargine/therapeutic use ; Insulin/therapeutic use ; Insulin, Regular, Human/therapeutic use ; Mass Spectrometry ; Chromatography, Liquid ; Glucose/therapeutic use ; Blood Glucose/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
PAQR9 regulates glucose homeostasis in diabetic mice and modulates insulin secretion in β cells in vitro under stress conditions.
Autorzy:
Li Z; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Lin Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhuo S; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Chen J; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Chen L; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Wang S; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Chen Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. Electronic address: .
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Źródło:
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2023 Sep 15; Vol. 575, pp. 112032. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Experimental*/metabolism
Insulin-Secreting Cells*/metabolism
Mice ; Animals ; Insulin Secretion ; Insulin/metabolism ; Streptozocin ; Thapsigargin/metabolism ; Glucose/metabolism ; Disease Models, Animal ; Diet, High-Fat ; Homeostasis ; Endoplasmic Reticulum Stress
Czasopismo naukowe
Szczegóły
Tytuł:
Platelet-derived lipids promote insulin secretion of pancreatic β cells.
Autorzy:
Karwen T; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Kolczynska-Matysiak K; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Gross C; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.
Löffler MC; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Friedrich M; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Loza-Valdes A; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Schmitz W; Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Wit M; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Dziaczkowski F; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Belykh A; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Trujillo-Viera J; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
El-Merahbi R; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Deppermann C; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Nawaz S; Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK.
Hastoy B; Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK.
Demczuk A; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Erk M; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Wieckowski MR; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
Rorsman P; Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK.; Department of Physiology, Institute of Neuroscience and Physiology, University of Göteborg, Göteborg, Sweden.; Oxford National Institute for Health Research, Biomedical Research Centre, Churchill Hospital, Oxford, UK.
Heinze KG; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.
Stegner D; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.
Nieswandt B; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.
Sumara G; Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Würzburg, Germany.; Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland.
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Źródło:
EMBO molecular medicine [EMBO Mol Med] 2023 Sep 11; Vol. 15 (9), pp. e16858. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin-Secreting Cells*
Humans ; Insulin Secretion ; Insulin/metabolism ; Blood Platelets ; Glucose/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Plasma insulin is required for the increase in plasma angiopoietin-like protein 8 in response to nutrient ingestion.
Autorzy:
Abu-Farha M; Biochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.
Alatrach M; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Abubaker J; Biochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.
Al-Khairi I; Biochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.
Cherian P; Biochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.
Agyin K; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Abdelgani S; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Norton L; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Adams J; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Al-Saeed D; Dasman Diabetes Institute, Kuwait City, Kuwait.
Al-Ozairi E; Dasman Diabetes Institute, Kuwait City, Kuwait.
DeFronzo RA; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
Al-Mulla F; Dasman Diabetes Institute, Kuwait City, Kuwait.
Abdul-Ghani M; Division of Diabetes, University of Texas Health Science Center, San Antonio, Texas, USA.
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Źródło:
Diabetes/metabolism research and reviews [Diabetes Metab Res Rev] 2023 Sep; Vol. 39 (6), pp. e3643. Date of Electronic Publication: 2023 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Glucose Intolerance*/metabolism
Prediabetic State*
Hyperinsulinism*
Insulin Resistance*/physiology
Peptide Hormones*
Humans ; Blood Glucose/metabolism ; Angiopoietin-Like Protein 8 ; Insulin/metabolism ; Glucose/metabolism ; Fasting ; Eating ; Insulin, Regular, Human ; Nutrients
Czasopismo naukowe
Szczegóły
Tytuł:
Cross-talk between insulin resistance and nitrogen species in hypoxia leads to deterioration of tissue and homeostasis.
Autorzy:
Sharma P; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India.
Sri Swetha Victoria V; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India.
Praneeth Kumar P; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India.
Karmakar S; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India.
Swetha M; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India.
Reddy A; Animal Cell Culture Laboratory, Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nādu, India. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2023 Sep; Vol. 122, pp. 110472. Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Insulin Resistance*
Humans ; Nitrogen/metabolism ; Insulin/metabolism ; Hypoxia ; Glucose/metabolism ; Homeostasis ; Inflammation ; Phosphorylation ; Insulin Receptor Substrate Proteins/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Real-world study of ethnic differences in glycaemic control and clinical characteristics among insulin-naïve people with type 2 diabetes initiating biphasic insulin aspart 30/70: A retrospective, observational cohort study in England.
Autorzy:
Davies MJ; Diabetes Research Centre, College of Life Sciences, Leicester General Hospital, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester General Hospital, Leicester, UK.
Alibegovic AC; Medical and Science, Diabetes, Novo Nordisk A/S, Søborg, Denmark.
Jensen AB; Real-World Science, Novo Nordisk A/S, Søborg, Denmark.
Munikrishnappa R; Global Medical Affairs, Novo Nordisk Global Business Services, Bengaluru, India.
Nordsborg RB; Data Science, Novo Nordisk A/S, Søborg, Denmark.
Braae UC; Real-World Science, Novo Nordisk A/S, Søborg, Denmark.
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Źródło:
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2023 Sep; Vol. 25 (9), pp. 2756-2764. Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin*/therapeutic use
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Adult ; Humans ; Glycated Hemoglobin ; Retrospective Studies ; Glycemic Control ; Treatment Outcome ; Insulin, Isophane/adverse effects ; Biphasic Insulins/adverse effects ; Insulin Aspart/adverse effects ; Hypoglycemic Agents/therapeutic use ; Insulin, Regular, Human ; Cohort Studies ; England/epidemiology
Czasopismo naukowe
Szczegóły
Tytuł:
In Vitro Biological Characterization of Recombinant Insulin Aspart from Biogenomics and Originator Insulin Aspart.
Autorzy:
Mishra AG; BioGenomics Ltd., Thane, Maharashtra, 400610, India. .
Deshmane RB; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
Thappa DK; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
Lona J; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
Ghade NS; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
Sonar SM; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
Krishnan AR; BioGenomics Ltd., Thane, Maharashtra, 400610, India.
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Źródło:
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2023 Sep; Vol. 37 (5), pp. 709-719. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin Aspart*/pharmacology
Receptor, Insulin*
Animals ; Rabbits ; Insulin/pharmacology ; Insulin/therapeutic use ; Glucose ; Hypoglycemic Agents/therapeutic use ; Blood Glucose
Czasopismo naukowe
Szczegóły
Tytuł:
Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo.
Autorzy:
Mukherjee S; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Chakraborty M; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Msengi EN; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Haubner J; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Zhang J; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Jellinek MJ; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Carlson HL; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Pyles K; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Ulmasov B; Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Lutkewitte AJ; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Carpenter D; Department of Pathology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
McCommis KS; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Ford DA; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Finck BN; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Neuschwander-Tetri BA; Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA.
Chakraborty A; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO, 63104, USA. Electronic address: .
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Źródło:
Molecular metabolism [Mol Metab] 2023 Sep; Vol. 75, pp. 101767. Date of Electronic Publication: 2023 Jul 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Non-alcoholic Fatty Liver Disease*/metabolism
Animals ; Female ; Humans ; Male ; Mice ; Adipose Tissue, Brown/metabolism ; Homeostasis ; Inflammation/metabolism ; Insulin/metabolism ; Insulin, Regular, Human/metabolism ; Obesity/metabolism ; Proteomics ; Proto-Oncogene Proteins c-akt/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.
Autorzy:
Sekiya M; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan. Electronic address: .
Ma Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Kainoh K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Saito K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Yamazaki D; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Tsuyuzaki T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Chen W; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Adi Putri PIP; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Ohno H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Miyamoto T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Takeuchi Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Murayama Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Sugano Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Osaki Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Iwasaki H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Yahagi N; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Suzuki H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Motomura K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
Matsuzaka T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan; Transborder Medical Research Center, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan.
Murata K; Laboratory Animal Resource Center in Transborder Medical Research Center, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan.
Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan.
Takahashi S; Laboratory Animal Resource Center in Transborder Medical Research Center, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan.
Shimano H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan.
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Źródło:
Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112914. Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Mice ; Humans ; Animals ; Insulin/metabolism ; Insulin Secretion ; Obesity/metabolism ; Glucose/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Altered insulin secretion dynamics relate to oxidative stress and inflammasome activation in children with obesity and insulin resistance.
Autorzy:
González-Domínguez Á; Grupo de Inflamación, Nutrición, Metabolismo y estrés Oxidativo, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), c/Doctor Marañón, 3 - Edificio Andrés Segovia, 11002, Cádiz, Spain.
Belmonte T; Translational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain.; CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Domínguez-Riscart J; Grupo de Inflamación, Nutrición, Metabolismo y estrés Oxidativo, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), c/Doctor Marañón, 3 - Edificio Andrés Segovia, 11002, Cádiz, Spain.; Unidad de Endocrinología Pediátrica y Diabetes, Servicio de Pediatría, Hospital Universitario Puerta del Mar, Cádiz, Spain.
Ruiz-Ocaña P; Grupo de Inflamación, Nutrición, Metabolismo y estrés Oxidativo, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), c/Doctor Marañón, 3 - Edificio Andrés Segovia, 11002, Cádiz, Spain.; Unidad de Endocrinología Pediátrica y Diabetes, Servicio de Pediatría, Hospital Universitario de Jerez, Jerez de la Frontera, Spain.
Muela-Zarzuela I; Grupo de Inflamación y Metabolismo Durante el Envejecimiento, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain.
Saez-Benito A; Servicio de Análisis Clínicos, Hospital Universitario Puerta del Mar, Cádiz, Spain.; Grupo de Diabetes Mellitus - Autoinmunidad y complicaciones crónicas, Implicaciones Patológicas, clínicas y terapéuticas, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain.
Montañez-Martínez R; Grupo de Daño cerebral Perinatal, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain.
Mateos RM; Grupo de Inflamación, Nutrición, Metabolismo y estrés Oxidativo, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), c/Doctor Marañón, 3 - Edificio Andrés Segovia, 11002, Cádiz, Spain. .; Departamento de Biomedicina, Facultad de Ciencias, Biotecnología y Salud Pública y Salud Pública, Universidad de Cádiz, Puerto Real, Spain. .
Lechuga-Sancho AM; Grupo de Inflamación, Nutrición, Metabolismo y estrés Oxidativo, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), c/Doctor Marañón, 3 - Edificio Andrés Segovia, 11002, Cádiz, Spain. .; Unidad de Endocrinología Pediátrica y Diabetes, Servicio de Pediatría, Hospital Universitario Puerta del Mar, Cádiz, Spain. .; Departamento Materno Infantil y Radiología, Facultad de Medicina, Universidad de Cádiz, Cádiz, Spain. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Aug 20; Vol. 21 (1), pp. 559. Date of Electronic Publication: 2023 Aug 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*
Insulin Resistance*
Child ; Humans ; Case-Control Studies ; Inflammasomes ; Inflammation ; Insulin ; Insulin Secretion ; Leukocytes, Mononuclear ; Obesity/complications ; Oxidative Stress ; Uric Acid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disrupting of family with sequence similarity 105, member A (Fam105a) deteriorates pancreatic β-cell physiology and insulin secretion in INS-1 cells.
Autorzy:
Taneera J; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates. Electronic address: .
Khalique A; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Salima A; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates; Laboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Mohammed Seddik Benyahia-Jijel, Jijel, Algeria.
Mohammed AK; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Sawan AS; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Aneis H; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Habib P; School of Information Technology and Computer Science (ITCS), Nile University, Giza, Egypt.
Abdrabh S; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Elemam NM; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Sharif-Askari NS; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Abu-Gharbieh E; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Saber-Ayad M; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
El-Huneidi W; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
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Źródło:
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2023 Aug 20; Vol. 574, pp. 111987. Date of Electronic Publication: 2023 Jun 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Humans ; Insulin Secretion ; Insulin/metabolism ; Cell Survival/genetics ; Glucose/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Hypoxia causes pancreatic β-cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE40.
Autorzy:
Tsuyama T; Center for Metabolic Regulation of Healthy Aging (CMHA), Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Sato Y; Department of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Yoshizawa T; Department of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Matsuoka T; First Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan.
Yamagata K; Center for Metabolic Regulation of Healthy Aging (CMHA), Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
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Źródło:
EMBO reports [EMBO Rep] 2023 Aug 03; Vol. 24 (8), pp. e56227. Date of Electronic Publication: 2023 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin-Secreting Cells*/metabolism
Mice ; Humans ; Animals ; Insulin Secretion ; Insulin/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Pancreas/metabolism ; Mice, Inbred Strains ; Hypoxia/genetics ; Hypoxia/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Response to insulin glargine 100 U/mL treatment in newly-defined subgroups of type 2 diabetes: Post hoc pooled analysis of insulin-naïve participants from nine randomised clinical trials.
Autorzy:
Landgraf W; Sanofi, Berlin, Germany. Electronic address: .
Bigot G; Ividata Life Sciences, Levallois-Perret, France.
Frier BM; The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Bolli GB; University of Perugia School of Medicine, Department of Medicine, Section of Endocrinology and Metabolism, Perugia, Italy.
Owens DR; Swansea University, Diabetes Research Group Cymru, College of Medicine, Swansea, UK.
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Źródło:
Primary care diabetes [Prim Care Diabetes] 2023 Aug; Vol. 17 (4), pp. 379-385. Date of Electronic Publication: 2023 May 02.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Insulin Resistance*
Male ; Female ; Humans ; Insulin Glargine/adverse effects ; Insulin/adverse effects ; Glycated Hemoglobin ; Hypoglycemic Agents/adverse effects ; Body Weight
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 543281

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