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Wyszukujesz frazę ""INTERLEUKIN-1"" wg kryterium: Temat


Tytuł :
Interleukin-36: Structure, Signaling and Function.
Autorzy :
Zhou L; AbbVie Bioresearch Center, Worcester, MA, USA. .
Todorovic V; AbbVie Inc., North Chicago, IL, USA.
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 21, pp. 191-210.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Interleukin-1*/genetics
Psoriasis*/genetics
Animals ; Interleukin-1 Receptor Accessory Protein ; Interleukins ; Mice ; Skin
Czasopismo naukowe
Tytuł :
Serial Systemic Injections of Endotoxin (LPS) Elicit Neuroprotective Spinal Cord Microglia through IL-1-Dependent Cross Talk with Endothelial Cells.
Autorzy :
Freria CM; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210 .; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Brennan FH; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; The Belford Center for Spinal Cord Injury, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Sweet DR; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Guan Z; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; The Belford Center for Spinal Cord Injury, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Hall JC; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; The Belford Center for Spinal Cord Injury, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Kigerl KA; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; The Belford Center for Spinal Cord Injury, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.
Nemeth DP; Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210.; Brain Institute, Florida Atlantic University, Jupiter, Florida 33458.
Liu X; Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210.; Brain Institute, Florida Atlantic University, Jupiter, Florida 33458.
Lacroix S; Axe neurosciences, Centre de recherche du Centre hospitalier universitaire (CHU) de Québec, and Département de médecine moléculaire, Université Laval, Québec, Québec G1V 4G2, Canada.
Quan N; Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210.; Brain Institute, Florida Atlantic University, Jupiter, Florida 33458.
Popovich PG; Center for Brain and Spinal Cord Repair, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210 .; The Belford Center for Spinal Cord Injury, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, Ohio 43210.; Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Nov 18; Vol. 40 (47), pp. 9103-9120. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Communication/*drug effects
Endothelial Cells/*drug effects
Interleukin-1/*physiology
Lipopolysaccharides/*pharmacology
Microglia/*drug effects
Neuroprotective Agents/*pharmacology
Spinal Cord/*drug effects
Animals ; Bromodeoxyuridine/pharmacology ; Endothelial Cells/metabolism ; Female ; Interleukin-1/biosynthesis ; Male ; Mice ; Mice, Inbred C57BL ; Motor Activity/drug effects ; Neurons/drug effects ; Neurons/pathology ; Paralysis/chemically induced ; Receptors, Interleukin-1 Type I/drug effects ; Receptors, Interleukin-1 Type I/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Spinal Cord/metabolism
Czasopismo naukowe
Tytuł :
IL-18 but Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease.
Autorzy :
Hohenester S; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
Kanitz V; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Schiergens T; Department of General, Visceral and Transplantation Surgery, University Hospital, LMU Munich, 81377 Munich.
Einer C; Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Nagel J; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
Wimmer R; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
Reiter FP; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
Gerbes AL; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
De Toni EN; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.
Bauer C; Division of Gastroenterology, Endocrinology, Infectiology and Metabolism, University Hospital Giessen and Marburg, Campus Marburg, Philipps University Marburg, 35043 Marburg, Germany.
Holdt L; Institute of Laboratory Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Mayr D; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Rust C; Department of Medicine I, Hospital Barmherzige Brüder, 80639 Munich, Germany.
Schnurr M; Division of Clinical Pharmacology, University Hospital, LMU Munich, 80336 Munich, Germany.
Zischka H; Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Toxicology and Environmental Hygiene, School of Medicine, Technical University Munich, 80802 Munich, Germany.
Geier A; Division of Hepatology, University Hospital Würzburg, 97080 Würzburg, Germany.
Denk G; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.; Transplantation Center Munich, University Hospital, LMU Munich, 81377 Munich, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 14; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 14.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Interleukin-1/*metabolism
Interleukin-18/*metabolism
Liver/*injuries
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Interleukin-1/genetics ; Interleukin-18/genetics ; Liver/pathology ; Male ; Mice ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/pathology ; Receptors, Interleukin-1/genetics ; Receptors, Interleukin-1/metabolism ; Receptors, Interleukin-18/genetics ; Receptors, Interleukin-18/metabolism
Czasopismo naukowe
Tytuł :
IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.
Autorzy :
Ngo VL; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Abo H; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Kuczma M; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Szurek E; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Moore N; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Medina-Contreras O; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Nusrat A; Department of Pathology, University of Michigan, Ann Arbor, MI 48109.
Merlin D; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Gewirtz AT; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Ignatowicz L; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Denning TL; Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 03; Vol. 117 (44), pp. 27540-27548. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Citrobacter rodentium/*immunology
Enterobacteriaceae Infections/*immunology
Receptors, Interleukin-1/*metabolism
Animals ; Citrobacter rodentium/pathogenicity ; Disease Models, Animal ; Enterobacteriaceae Infections/microbiology ; Interleukin-1/metabolism ; Intestinal Mucosa/immunology ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/microbiology ; Mice ; Mice, Knockout ; Receptors, Interleukin-1/genetics ; Signal Transduction/genetics ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes.
Autorzy :
Zhou H; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Wang H; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; School of Life Sciences, Lanzhou University, Lanzhou, China.
Yu M; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA.
Schugar RC; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Qian W; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Tang F; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Liu W; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Yang H; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
McDowell RE; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Zhao J; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Gao J; Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.
Dongre A; Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.
Carman JA; Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.; Immunology Discovery, Janssen Research and Development, Spring House, PA, USA.
Yin M; Imaging Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Drazba JA; Imaging Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Dent R; University of Ottawa and Ottawa Hospital, Ottawa, Ontario, Canada.
Hine C; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Chen YR; Department of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
Smith JD; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Fox PL; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Brown JM; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Li X; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Oct; Vol. 21 (10), pp. 1219-1231. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes/*immunology
Inflammation/*immunology
Interleukin-1/*metabolism
Interleukin-1 Receptor-Associated Kinases/*metabolism
Mitochondrial Membranes/*metabolism
Obesity/*immunology
Adipocytes/pathology ; Animals ; Cells, Cultured ; Humans ; Interleukin-1 Receptor-Associated Kinases/genetics ; Male ; Mice ; Mice, Knockout ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/metabolism ; Oxidative Phosphorylation ; Protein Transport ; Receptors, Interleukin-1/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
IL-37 inhibits M1-like macrophage activation to ameliorate temporomandibular joint inflammation through the NLRP3 pathway.
Autorzy :
Luo P; Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University.; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Peng S; Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University.; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Yan Y; Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University.; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Ji P; Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University.; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
Xu J; Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University.; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences.; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Oct 01; Vol. 59 (10), pp. 3070-3080.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Polarity/*drug effects
Interleukin-1/*pharmacology
Macrophage Activation/*drug effects
Macrophages/*drug effects
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Temporomandibular Joint Disorders/*therapy
Blotting, Western ; Chondrocytes/drug effects ; Chondrocytes/metabolism ; Culture Media, Conditioned/pharmacology ; Cytokines/metabolism ; Freund's Adjuvant ; Heterocyclic Compounds, 4 or More Rings/pharmacology ; Humans ; Inflammasomes/drug effects ; Macrophages/metabolism ; Mandibular Condyle/pathology ; Osteoarthritis/chemically induced ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Osteoarthritis/therapy ; RNA, Small Interfering/pharmacology ; Real-Time Polymerase Chain Reaction ; Receptors, Interleukin-1/metabolism ; Sulfones/pharmacology ; Synovial Membrane/pathology ; Temporomandibular Joint Disorders/chemically induced ; Temporomandibular Joint Disorders/metabolism ; Temporomandibular Joint Disorders/pathology ; Up-Regulation
Czasopismo naukowe
Tytuł :
IL-1 induces throboxane-A2 (TxA2) in COVID-19 causing inflammation and micro-thrombi: inhibitory effect of the IL-1 receptor antagonist (IL-1Ra).
Autorzy :
Conti P; Postgraduate Medical School, University of Chieti, 66013 Chieti, Italy.
Caraffa A; School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Gallenga CE; Department of Biomedical Sciences and Specialist Surgery, Section of Ophthalmology, University of Ferrara, 44121 Ferrara, Italy.
Ross R; University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Kritas SK; Department of Microbiology, University of Thessaloniki, 54124 Thessaloniki, Greece.
Frydas I; School of Veterinary Medicine, University of Thessaloniki, 54124 Thessaloniki, Greece.
Younes A; Centro Medico 'Mai più Dolore', 65100 Pescara, Italy.
Di Emidio P; Maxillofacial Surgery 'G. Mazzini' Hospital, 64100 Teramo, Italy.
Ronconi G; Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00100 Roma, Italy.
Toniato E; Department of Medical, Oral and Biotechnological Sciences, University of Chieti, Chieti, Italy.
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Źródło :
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2020 Sep-Oct,; Vol. 34 (5), pp. 1623-1627.
Typ publikacji :
Editorial
MeSH Terms :
Coronavirus Infections/*pathology
Inflammation/*virology
Interleukin 1 Receptor Antagonist Protein/*therapeutic use
Interleukin-1/*physiology
Pneumonia, Viral/*pathology
Thrombosis/*virology
Thromboxane A2/*physiology
Animals ; Betacoronavirus ; COVID-19 ; Humans ; Pandemics ; Receptors, Interleukin-1 ; SARS-CoV-2
Opinia redakcyjna
Tytuł :
Cytokine IL-36γ improves CAR T-cell functionality and induces endogenous antitumor response.
Autorzy :
Li X; Weill Cornell Graduate School of Medical Sciences, New York, NY, 10065, USA.; Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Daniyan AF; Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Lopez AV; Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Purdon TJ; Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Brentjens RJ; Weill Cornell Graduate School of Medical Sciences, New York, NY, 10065, USA. .; Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. .; Molecular Pharmacology & Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. .; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. .; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. .
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Źródło :
Leukemia [Leukemia] 2021 Feb; Vol. 35 (2), pp. 506-521. Date of Electronic Publication: 2020 May 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Cellular/*immunology
Immunotherapy, Adoptive/*methods
Interleukin-1/*metabolism
Lymphocyte Activation/*immunology
Lymphoma, T-Cell/*immunology
Receptors, Antigen, T-Cell/*immunology
Receptors, Chimeric Antigen/*immunology
Animals ; Antigen-Presenting Cells ; Apoptosis ; Cell Proliferation ; Female ; Humans ; Interleukin-1/genetics ; Lymphoma, T-Cell/metabolism ; Lymphoma, T-Cell/pathology ; Lymphoma, T-Cell/therapy ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Myeloid Differentiation Factor 88/physiology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study.
Autorzy :
Kooistra EJ; Department of Intensive Care Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Waalders NJB; Department of Intensive Care Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Grondman I; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Janssen NAF; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
de Nooijer AH; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Netea MG; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany.
van de Veerdonk FL; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Ewalds E; Department of Intensive Care Medicine, Bernhoven Hospital, 5406PT, Uden, The Netherlands.
van der Hoeven JG; Department of Intensive Care Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Kox M; Department of Intensive Care Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands.
Pickkers P; Department of Intensive Care Medicine, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands. .; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6500HB, Nijmegen, The Netherlands. .
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Corporate Authors :
RCI-COVID-19 Study Group
Źródło :
Critical care (London, England) [Crit Care] 2020 Dec 10; Vol. 24 (1), pp. 688. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*drug therapy
Interleukin 1 Receptor Antagonist Protein/*therapeutic use
Receptors, Interleukin-1/*antagonists & inhibitors
Aged ; COVID-19/physiopathology ; Cohort Studies ; Critical Illness/therapy ; Female ; Humans ; Interleukin 1 Receptor Antagonist Protein/adverse effects ; Interleukin 1 Receptor Antagonist Protein/pharmacology ; Male ; Middle Aged ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Prospective Studies ; Receptors, Interleukin-1/therapeutic use ; Statistics, Nonparametric
Czasopismo naukowe
Tytuł :
IL36 Cooperates With Anti-CTLA-4 mAbs to Facilitate Antitumor Immune Responses.
Autorzy :
Qu Q; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Zhai Z; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Xu J; Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States.
Li S; Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States.
Chen C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Lu B; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.; UPMC Hillman Cancer Center, Pittsburgh, PA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Apr 15; Vol. 11, pp. 634. Date of Electronic Publication: 2020 Apr 15 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antineoplastic Agents, Immunological/*therapeutic use
Immunotherapy/*methods
Interleukin-1/*metabolism
Melanoma/*therapy
Skin Neoplasms/*therapy
T-Lymphocyte Subsets/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; CTLA-4 Antigen/immunology ; Cell Movement ; Drug Synergism ; Drug Therapy, Combination ; Humans ; Interleukin-1/genetics ; Lymphocyte Activation ; Melanoma/immunology ; Melanoma, Experimental ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasm Transplantation ; Receptors, Interleukin-1/genetics ; Receptors, Interleukin-1/metabolism ; Skin Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Antibody-mediated inhibition of syndecan-4 dimerisation reduces interleukin (IL)-1 receptor trafficking and signalling.
Autorzy :
Godmann L; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
Bollmann M; Department of Orthopaedic Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Korb-Pap A; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
König U; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
Sherwood J; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
Beckmann D; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
Mühlenberg K; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany.
Echtermeyer F; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hanover, Germany.
Whiteford J; Centre for Microvascular Research, Queen Mary University of London, London, UK.
De Rossi G; Centre for Microvascular Research, Queen Mary University of London, London, UK.
Pap T; Institute of Musculoskeletal Medicine (IMM), University Muenster, Muenster, Germany .
Bertrand J; Department of Orthopaedic Surgery, Otto-von-Guericke University, Magdeburg, Germany.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2020 Apr; Vol. 79 (4), pp. 481-489. Date of Electronic Publication: 2020 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Blocking/*pharmacology
Arthritis, Rheumatoid/*metabolism
Receptors, Interleukin-1 Type I/*drug effects
Syndecan-4/*antagonists & inhibitors
Animals ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/pathology ; Dimerization ; Disease Models, Animal ; Extracellular Signal-Regulated MAP Kinases/drug effects ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Fibroblasts/metabolism ; Gene Knockout Techniques ; Heparitin Sulfate ; Hindlimb ; Humans ; Interleukin-1/metabolism ; Interleukin-1beta/metabolism ; MAP Kinase Signaling System ; Matrix Metalloproteinase 3/metabolism ; Mice ; Mice, Transgenic ; NIH 3T3 Cells ; Osteoarthritis/genetics ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Phosphorylation/drug effects ; Protein Transport ; Receptors, Interleukin-1 Type I/metabolism ; Signal Transduction ; Syndecan-4/genetics ; Syndecan-4/metabolism ; Synovial Membrane/metabolism ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
IRAK family in inflammatory autoimmune diseases.
Autorzy :
Su LC; Department of Rheumatology and Immunology, Minda Hospital of Hubei Minzu University, Enshi, Hubei, China.
Xu WD; Department of Evidence-Based Medicine, Southwest Medical University, Luzhou, Sichuan, China. Electronic address: .
Huang AF; Department of Rheumatology and Immunology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. Electronic address: .
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Źródło :
Autoimmunity reviews [Autoimmun Rev] 2020 Mar; Vol. 19 (3), pp. 102461. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Signal Transduction*
Autoimmune Diseases/*enzymology
Inflammation/*immunology
Interleukin-1 Receptor-Associated Kinases/*immunology
Animals ; Humans ; Receptors, Interleukin-1/metabolism ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
IL-1-dependent electrophysiological changes and cardiac neural remodeling in a mouse model of Kawasaki disease vasculitis.
Autorzy :
Abe M; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Rastelli DD; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Division of Gastroenterology and Nutrition, Boston Children's Hospital, Boston, MA, USA.
Gomez AC; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Cingolani E; Cedars-Sinai Medical Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.
Lee Y; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Soni PR; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Fishbein MC; Department of Pathology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Lehman TJA; Division of Rheumatology, Department of Pediatrics, Weill Cornell Medical School, New York, NY, USA.
Shimada K; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Crother TR; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Chen S; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Noval Rivas M; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Arditi M; Divisions of Infectious Diseases and Immunology, Departments of Biomedical Sciences and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Cedars-Sinai Medical Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.; Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2020 Mar; Vol. 199 (3), pp. 303-313. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Disease Models, Animal*
Interleukin-1/*metabolism
Mucocutaneous Lymph Node Syndrome/*physiopathology
Vasculitis/*physiopathology
Animals ; Antirheumatic Agents/pharmacology ; Biological Products/toxicity ; Cell Wall/chemistry ; Child ; Electrocardiography/drug effects ; Female ; Humans ; Interleukin 1 Receptor Antagonist Protein/pharmacology ; Interleukin-1/genetics ; Lactobacillus casei/chemistry ; Mice, Inbred C57BL ; Mice, Knockout ; Mucocutaneous Lymph Node Syndrome/chemically induced ; Mucocutaneous Lymph Node Syndrome/therapy ; Nerve Growth Factor/blood ; Receptors, Interleukin-1 Type I/genetics ; Receptors, Interleukin-1 Type I/metabolism ; Signal Transduction/drug effects ; Vasculitis/chemically induced ; Vasculitis/therapy
Czasopismo naukowe
Tytuł :
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
Autorzy :
He L; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China; Department of Anesthesiology, Yan'an Hospital of Kunming City, Kunming Medical University, Kunming, Yunnan Province, 650051, China.
Wang Z; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China.
Zhou R; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China.
Xiong W; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China.
Yang Y; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China.
Song N; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China.
Qian J; Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110993. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Dexmedetomidine/*pharmacology
Interleukin-1 Receptor-Associated Kinases/*metabolism
MicroRNAs/*metabolism
Myocardial Infarction/*prevention & control
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*drug effects
NF-kappa B/*metabolism
TNF Receptor-Associated Factor 6/*metabolism
Animals ; Cell Hypoxia ; Cell Line ; Disease Models, Animal ; Gene Expression Regulation ; Interleukin-1 Receptor-Associated Kinases/genetics ; Male ; MicroRNAs/genetics ; Myocardial Infarction/enzymology ; Myocardial Infarction/genetics ; Myocardial Infarction/pathology ; Myocardial Reperfusion Injury/enzymology ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/enzymology ; Myocytes, Cardiac/pathology ; NF-kappa B/genetics ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction ; TNF Receptor-Associated Factor 6/genetics
Czasopismo naukowe
Tytuł :
Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model.
Autorzy :
Takenaga K; Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Nitona, Chuoh-ku, Chiba, Japan.
Akimoto M; Department of Biochemistry, Teikyo University School of Medicine, Kaga, Itabashi-ku, Tokyo, Japan.
Koshikawa N; Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Nitona, Chuoh-ku, Chiba, Japan.
Nagase H; Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Nitona, Chuoh-ku, Chiba, Japan.
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Źródło :
PloS one [PLoS One] 2020 Apr 27; Vol. 15 (4), pp. e0232230. Date of Electronic Publication: 2020 Apr 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*physiology
Interleukin-1 Receptor-Like 1 Protein/*metabolism
Interleukin-33/*metabolism
Pancreatic Neoplasms/*metabolism
Pancreatic Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Humans ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; PC-3 Cells ; Pancreas/metabolism ; Pancreas/pathology ; Receptors, Interleukin-1/metabolism ; Signal Transduction/physiology ; Tumor Microenvironment/physiology ; Up-Regulation/physiology
Czasopismo naukowe
Tytuł :
Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling.
Autorzy :
Li X; Department of Physics, Xiamen University, Xiamen 361005, China.; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen 361102, China.
Zhong CQ; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen 361102, China.
Yin Z; Department of Physics, Xiamen University, Xiamen 361005, China.
Qi H; Complex Systems Research Center, Shanxi University, Taiyuan 030006, China.
Xu F; Department of Physics, Xiamen University, Xiamen 361005, China.
He Q; Department of Physics, Xiamen University, Xiamen 361005, China.
Shuai J; Department of Physics, Xiamen University, Xiamen 361005, China.; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen 361102, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 26; Vol. 21 (9). Date of Electronic Publication: 2020 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Lipopolysaccharides/*pharmacology
Membrane Glycoproteins/*metabolism
Myeloid Differentiation Factor 88/*metabolism
Receptors, Interleukin-1/*metabolism
Toll-Like Receptor 4/*metabolism
Algorithms ; Animals ; Interleukin-1 Receptor-Associated Kinases/metabolism ; Mice ; Models, Theoretical ; Multiprotein Complexes/metabolism ; RAW 264.7 Cells ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
A new insight into thymosin β4, a promising therapeutic approach for neurodegenerative disorders.
Autorzy :
Shomali N; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Deljavanghodrati M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Akbari M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hemmatzadeh M; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammadi H; Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Jang Y; Department of Immunology, Center of Clinical Medicine and Laboratory, Jiangsu University, Zhenjiang, China.
Xu H; Department of Immunology, Center of Clinical Medicine and Laboratory, Jiangsu University, Zhenjiang, China.
Sandoghchian Shotorbani S; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Immunology, Center of Clinical Medicine and Laboratory, Jiangsu University, Zhenjiang, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Apr; Vol. 235 (4), pp. 3270-3279. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Inflammation/*genetics
Interleukin-1 Receptor-Associated Kinases/*genetics
MicroRNAs/*genetics
Neurodegenerative Diseases/*genetics
Thymosin/*genetics
Humans ; Inflammation/pathology ; Interleukin-1/genetics ; NF-kappa B/genetics ; Neurodegenerative Diseases/pathology ; Signal Transduction/genetics ; Toll-Like Receptors/genetics
Czasopismo naukowe
Tytuł :
Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling.
Autorzy :
Chen L; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.; Department of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325001, China.
Zheng L; Department of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310000, China.
Chen P; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325001, China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Nov 25; Vol. 63 (22), pp. 13316-13329. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Myeloid Differentiation Factor 88/*antagonists & inhibitors
Myeloid Differentiation Factor 88/*metabolism
Receptors, Interleukin-1/*metabolism
Signal Transduction/*physiology
Toll-Like Receptors/*metabolism
Amino Acid Sequence ; Animals ; Drug Discovery/methods ; Drug Discovery/trends ; Humans ; Myeloid Differentiation Factor 88/chemistry ; Piperazines/chemistry ; Piperazines/metabolism ; Piperazines/pharmacology ; Protein Processing, Post-Translational/drug effects ; Protein Processing, Post-Translational/physiology ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Receptors, Interleukin-1/chemistry ; Signal Transduction/drug effects ; Thiazoles/chemistry ; Thiazoles/metabolism ; Thiazoles/pharmacology ; Toll-Like Receptors/chemistry
Czasopismo naukowe
Tytuł :
miR-205/IRAK2 signaling pathway is associated with urban airborne PM 2.5 -induced myocardial toxicity.
Autorzy :
Feng L; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, P.R. China.; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, P.R. China.
Wei J; Key Laboratory of Cardiovascular Epidemiology & Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liang S; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, P.R. China.; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, P.R. China.
Sun Z; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, P.R. China.; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, P.R. China.
Duan J; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, P.R. China.; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, P.R. China.
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Źródło :
Nanotoxicology [Nanotoxicology] 2020 Nov; Vol. 14 (9), pp. 1198-1212. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Air Pollutants/*toxicity
Heart/*drug effects
Interleukin-1 Receptor-Associated Kinases/*metabolism
MicroRNAs/*metabolism
Myocardium/*metabolism
Particulate Matter/*toxicity
Air Pollutants/chemistry ; Animals ; Apoptosis/drug effects ; Cell Line ; Cell Survival/drug effects ; Down-Regulation/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Interleukin-1 Receptor-Associated Kinases/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Malondialdehyde/metabolism ; MicroRNAs/genetics ; Myocardium/ultrastructure ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/ultrastructure ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Particulate Matter/chemistry ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Interaction between MyD88, TIRAP and IL1RL1 against Helicobacter pylori infection.
Autorzy :
Fulgione A; Department of Agriculture Sciences, University of Naples 'Federico II', Via Università, 100, 80055, Portici, Naples, Italy.; Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute, 2, 80055, Portici, Naples, Italy.
Papaianni M; Department of Agriculture Sciences, University of Naples 'Federico II', Via Università, 100, 80055, Portici, Naples, Italy.
Cuomo P; Department of Agriculture Sciences, University of Naples 'Federico II', Via Università, 100, 80055, Portici, Naples, Italy.
Paris D; Institute of Biomolecular Chemistry, National Research Council, Via Campi Flegrei, 34, 80078, Pozzuoli, Naples, Italy.
Romano M; Hepatogastroenterology Unit, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', via Pansini, 5, 80131, Naples, Italy.
Tuccillo C; Hepatogastroenterology Unit, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', via Pansini, 5, 80131, Naples, Italy.
Palomba L; Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Via Santa Chiara, 27, 61029, Urbino, Italy.
Medaglia C; Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Rue du Général-Dufour, 24, 1211, Genève 4, Switzerland.
De Seta M; Fondazione Evangelica Betania, Via Argine, 604, 80147, Naples, Italy.
Esposito N; Fondazione Evangelica Betania, Via Argine, 604, 80147, Naples, Italy.
Motta A; Institute of Biomolecular Chemistry, National Research Council, Via Campi Flegrei, 34, 80078, Pozzuoli, Naples, Italy.
Iannelli A; Université Côte D'Azur, Campus Valrose, Batiment L, Avenue de Valrose, 28, 06108, Nice CEDEX 2, France.; Centre Hospitalier Universitaire de Nice - Digestive Surgery and Liver Transplantation Unit, Archet 2 Hospital, Route Saint-Antoine de Ginestière 151, CS 23079, 06202, Nice CEDEX 3, France.; Inserm, U1065, Team 8 'Hepatic Complications of Obesity and Alcohol', Route Saint Antoine de Ginestière 151, BP 2 3194, 06204, Nice CEDEX 3, France.
Iannelli D; Department of Agriculture Sciences, University of Naples 'Federico II', Via Università, 100, 80055, Portici, Naples, Italy. .
Capparelli R; Department of Agriculture Sciences, University of Naples 'Federico II', Via Università, 100, 80055, Portici, Naples, Italy.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 28; Vol. 10 (1), pp. 15831. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Helicobacter pylori*
Helicobacter Infections/*metabolism
Interleukin-1 Receptor-Like 1 Protein/*metabolism
Membrane Glycoproteins/*metabolism
Myeloid Differentiation Factor 88/*metabolism
Receptors, Interleukin-1/*metabolism
Disease Resistance/genetics ; Helicobacter Infections/genetics ; Humans ; Interleukin-1 Receptor-Like 1 Protein/genetics ; Magnetic Resonance Spectroscopy ; Membrane Glycoproteins/genetics ; Myeloid Differentiation Factor 88/genetics ; Real-Time Polymerase Chain Reaction ; Receptors, Interleukin-1/genetics
Czasopismo naukowe

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