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Tytuł :
Antiviral and virucidal activities of lycorine on duck tembusu virus in vitro by blocking viral internalization and entry.
Autorzy :
Lv X; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhang M; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Yu S; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhang C; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Fang T; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Liu D; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Jia B; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhu M; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wang B; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wang Q; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhu Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wang G; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China; Anhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Hefei 230036, China. Electronic address: .
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Źródło :
Poultry science [Poult Sci] 2021 Oct; Vol. 100 (10), pp. 101404. Date of Electronic Publication: 2021 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Poultry Diseases*
Virus Internalization*
Amaryllidaceae Alkaloids ; Animals ; Antiviral Agents/pharmacology ; Chickens ; Ducks ; Flavivirus ; Phenanthridines
SCR Organism :
Tembusu virus
Czasopismo naukowe
Tytuł :
SARS-CoV-2 S glycoprotein binding to multiple host receptors enables cell entry and infection.
Autorzy :
Trbojević-Akmačić I; Genos Glycoscience Research Laboratory, Zagreb, Croatia. .
Petrović T; Genos Glycoscience Research Laboratory, Zagreb, Croatia.
Lauc G; Genos Glycoscience Research Laboratory, Zagreb, Croatia.; Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia.
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Źródło :
Glycoconjugate journal [Glycoconj J] 2021 Oct; Vol. 38 (5), pp. 611-623. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Virus Internalization*
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*metabolism
Glycoproteins/*metabolism
Lectins, C-Type/*metabolism
SARS-CoV-2/*physiology
Spike Glycoprotein, Coronavirus/*metabolism
Glycosylation ; Humans
Czasopismo naukowe
Tytuł :
Proteases and variants: context matters for SARS-CoV-2 entry assays.
Autorzy :
Stevens CS; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, United States.
Oguntuyo KY; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, United States.
Lee B; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, United States. Electronic address: .
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Źródło :
Current opinion in virology [Curr Opin Virol] 2021 Oct; Vol. 50, pp. 49-58. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Virus Internalization*
COVID-19/*etiology
Peptide Hydrolases/*physiology
SARS-CoV-2/*physiology
Humans ; Mutation ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19.
Autorzy :
Rezq S; Department of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Women's Health Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Cardio Renal Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Huffman AM; Department of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Women's Health Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Cardio Renal Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.
Basnet J; Department of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Women's Health Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Cardio Renal Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.
Yanes Cardozo LL; Department of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Women's Health Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Cardio Renal Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Department of Medicine, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.
Romero DG; Department of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Women's Health Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.; Cardio Renal Research Center, University of Mississippi Medical Center, 2500 N, State Street, Jackson, MS 39216, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 09; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/immunology
COVID-19*/virology
Obesity*/immunology
Obesity*/virology
Virus Internalization*
Polycystic Ovary Syndrome/*virology
Receptors, Coronavirus/*immunology
SARS-CoV-2/*physiology
Animals ; Female ; Heart ; Kidney ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Antiviral activity and mechanism of ESC-1GN from skin secretion of Hylarana guentheri against influenza A virus.
Autorzy :
Yang J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Zhang B; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Huang Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Liu T; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Zeng B; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Chai J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Wu J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
Xu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.; Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Shatai Nan Road, No. 1023-1063, Guangzhou, Guangdong 510515, China.
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Źródło :
Journal of biochemistry [J Biochem] 2021 Sep 07; Vol. 169 (6), pp. 757-765.
Typ publikacji :
Journal Article
MeSH Terms :
Virus Internalization*
Amphibian Proteins/*chemistry
Antiviral Agents/*pharmacology
Influenza A virus/*drug effects
Influenza, Human/*drug therapy
Peptide Fragments/*pharmacology
Skin/*metabolism
A549 Cells ; Animals ; Dogs ; Humans ; Influenza, Human/virology ; Madin Darby Canine Kidney Cells ; Ranidae ; Virus Replication
Czasopismo naukowe
Tytuł :
Broad betacoronavirus neutralization by a stem helix-specific human antibody.
Autorzy :
Pinto D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sauer MM; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Czudnochowski N; Vir Biotechnology, San Francisco, CA 94158, USA.
Low JS; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Housley MP; Vir Biotechnology, San Francisco, CA 94158, USA.
Noack J; Vir Biotechnology, San Francisco, CA 94158, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Guarino B; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Rosen LE; Vir Biotechnology, San Francisco, CA 94158, USA.
di Iulio J; Vir Biotechnology, San Francisco, CA 94158, USA.
Jerak J; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Kaiser H; Vir Biotechnology, San Francisco, CA 94158, USA.
Islam S; Vir Biotechnology, San Francisco, CA 94158, USA.
Jaconi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sprugasci N; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Abdelnabi R; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Foo C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Coelmont L; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Bartha I; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Bianchi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Silacci-Fregni C; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Bassi J; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Marzi R; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Vetti E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Cassotta A; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Ceschi A; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.
Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Clinical School, University of New South Wales, Sydney, NSW, 2052, Australia.
Cippà PE; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Faculty of Medicine, University of Zurich, 8057 Zurich, Switzerland.
Giannini O; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Ceruti S; Intensive Care Unit, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Riva A; III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.
Benigni F; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Piccoli L; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Pizzuto MS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Smithey M; Vir Biotechnology, San Francisco, CA 94158, USA.
Hong D; Vir Biotechnology, San Francisco, CA 94158, USA.
Telenti A; Vir Biotechnology, San Francisco, CA 94158, USA.
Lempp FA; Vir Biotechnology, San Francisco, CA 94158, USA.
Neyts J; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA 94158, USA.
Lanzavecchia A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sallusto F; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Snell G; Vir Biotechnology, San Francisco, CA 94158, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA 94158, USA.; UT Southwestern Medical Center, Dallas, TX 75390, USA.; Washington University School of Medicine, St. Louis, MO 63110, USA.
Beltramello M; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Sep 03; Vol. 373 (6559), pp. 1109-1116. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
Antibodies, Monoclonal/*immunology
Antibodies, Neutralizing/*immunology
Betacoronavirus/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*immunology
Viral Vaccines/*immunology
Animals ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Neutralizing/isolation & purification ; Convalescence ; Cricetinae ; Cross Reactions ; Humans ; Immunoglobulin Fab Fragments/immunology ; Immunoglobulin Fc Fragments/immunology ; Jurkat Cells ; Lung/immunology ; Membrane Fusion/immunology ; Neutralization Tests ; Peptide Mapping ; Protein Conformation, alpha-Helical ; SARS-CoV-2/immunology ; Spike Glycoprotein, Coronavirus/genetics ; Viral Load/immunology
Czasopismo naukowe
Tytuł :
Enrichment of SARS-CoV-2 Entry Factors and Interacting Intracellular Genes in Tissue and Circulating Immune Cells.
Autorzy :
Devaprasad A; Center for Translational Immunology, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Pandit A; Center for Translational Immunology, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
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Źródło :
Viruses [Viruses] 2021 Sep 02; Vol. 13 (9). Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Susceptibility*
Virus Internalization*
COVID-19/*etiology
Host-Pathogen Interactions/*genetics
Host-Pathogen Interactions/*immunology
SARS-CoV-2/*physiology
COVID-19/blood ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Humans ; Immune System/immunology ; Immune System/metabolism ; Immunity, Innate ; Macrophages/immunology ; Macrophages/metabolism ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Autorzy :
Tamura Y; Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.; Research Institute for Sport Science, Nippon Sport Science University, Tokyo, Japan.; Faculty of Sport Science, Nippon Sport Science University, Tokyo, Japan.
Jee E; Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.
Kouzaki K; Research Institute for Sport Science, Nippon Sport Science University, Tokyo, Japan.; Graduate School of Medical and Health Science, Nippon Sport Science University, Tokyo, Japan.; Faculty of Medical Science, Nippon Sport Science University, Tokyo, Japan.
Kotani T; Research Institute for Sport Science, Nippon Sport Science University, Tokyo, Japan.
Nakazato K; Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.; Research Institute for Sport Science, Nippon Sport Science University, Tokyo, Japan.; Graduate School of Medical and Health Science, Nippon Sport Science University, Tokyo, Japan.; Faculty of Medical Science, Nippon Sport Science University, Tokyo, Japan.
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Źródło :
Physiological reports [Physiol Rep] 2021 Sep; Vol. 9 (17), pp. e15014.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Physical Conditioning, Animal*
Physical Endurance*
Virus Internalization*
COVID-19/*virology
Receptors, Virus/*metabolism
SARS-CoV-2/*pathogenicity
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; COVID-19/enzymology ; Furin/metabolism ; Host-Pathogen Interactions ; Male ; Mice, Inbred C57BL ; Neuropilin-1/metabolism ; Running ; Serine Endopeptidases/metabolism
Czasopismo naukowe
Tytuł :
Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2.
Autorzy :
Colson A; Pole of Obstetrics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; Division of Obstetrics, Saint-Luc University Hospital, Brussels, Belgium. Electronic address: .
Depoix CL; Pole of Obstetrics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Dessilly G; Medical Microbiology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Baldin P; Department of Pathology, Saint-Luc University Hospital, Brussels, Belgium.
Danhaive O; Division of Neonatology, Saint-Luc University Hospital, Brussels, Belgium; Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, California.
Hubinont C; Pole of Obstetrics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; Division of Obstetrics, Saint-Luc University Hospital, Brussels, Belgium.
Sonveaux P; Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Debiève F; Pole of Obstetrics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; Division of Obstetrics, Saint-Luc University Hospital, Brussels, Belgium.
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Źródło :
The American journal of pathology [Am J Pathol] 2021 Sep; Vol. 191 (9), pp. 1610-1623. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/enzymology
COVID-19*/pathology
Gene Expression Regulation, Enzymologic*
Placenta Diseases*/enzymology
Placenta Diseases*/pathology
Pregnancy Complications, Infectious*/enzymology
Pregnancy Complications, Infectious*/pathology
Trophoblasts*/enzymology
Trophoblasts*/pathology
Virus Internalization*
Angiotensin-Converting Enzyme 2/*biosynthesis
SARS-CoV-2/*metabolism
Serine Endopeptidases/*biosynthesis
Adult ; Female ; Humans ; Pregnancy
Czasopismo naukowe
Tytuł :
An optimized and robust SARS-CoV-2 pseudovirus system for viral entry research.
Autorzy :
Yang P; College of Life Sciences, Henan Normal University, Xinxiang 453007, China; Beijing Institute of Radiation Medicine, Beijing 100850, China.
Yang Y; Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wu Y; Beijing Institute of Radiation Medicine, Beijing 100850, China.
Huang C; Beijing Institute of Radiation Medicine, Beijing 100850, China; Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang 421001, China.
Ding Y; Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wang X; Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: .
Wang S; College of Life Sciences, Henan Normal University, Xinxiang 453007, China; Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: .
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Źródło :
Journal of virological methods [J Virol Methods] 2021 Sep; Vol. 295, pp. 114221. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*/drug effects
Neutralization Tests/*methods
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/pharmacology ; Animals ; Antibodies, Neutralizing/pharmacology ; Antiviral Agents/pharmacology ; Cell Line ; Genes, Reporter ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Lentivirus/genetics ; Luciferases, Firefly/genetics ; Luciferases, Firefly/metabolism ; Recombinant Proteins/pharmacology ; SARS-CoV-2/drug effects ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Virion
Czasopismo naukowe
Tytuł :
Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains.
Autorzy :
Qing E; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Kicmal T; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Kumar B; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Hawkins GM; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Timm E; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
Perlman S; Department of Microbiology and Immunology, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Gallagher T; Department of Microbiology and Immunology, Loyola University Chicagogrid.164971.c, Maywood, Illinois, USA.
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Źródło :
MBio [mBio] 2021 Aug 31; Vol. 12 (4), pp. e0159021. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Virus Internalization*
COVID-19/*transmission
SARS-CoV-2/*genetics
Spike Glycoprotein, Coronavirus/*genetics
Angiotensin-Converting Enzyme 2/metabolism ; COVID-19/pathology ; Cell Line, Tumor ; HEK293 Cells ; HeLa Cells ; Humans ; Membrane Fusion/physiology ; Protein Domains/physiology ; Receptors, Virus/metabolism ; Spike Glycoprotein, Coronavirus/metabolism
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment.
Autorzy :
Wu CT; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lidsky PV; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.
Xiao Y; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.
Lee IT; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Cheng R; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA, USA.
Nakayama T; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA; Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan.
Jiang S; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Demeter J; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Bevacqua RJ; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chang CA; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Diabetes Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.
Whitener RL; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stalder AK; Institute of Pathology, University of Basel, Schönbeinstrasse 40, 4003 Basel, Switzerland.
Zhu B; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chen H; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Goltsev Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Tzankov A; Institute of Pathology, University of Basel, Schönbeinstrasse 40, 4003 Basel, Switzerland.
Nayak JV; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Nolan GP; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Matter MS; Institute of Pathology, University of Basel, Schönbeinstrasse 40, 4003 Basel, Switzerland. Electronic address: .
Andino R; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: .
Jackson PK; Baxter Laboratory, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Diabetes Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA. Electronic address: .
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Źródło :
Cell metabolism [Cell Metab] 2021 Aug 03; Vol. 33 (8), pp. 1565-1576.e5. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
COVID-19/*virology
Diabetes Mellitus/*virology
Insulin-Secreting Cells/*virology
Neuropilin-1/*metabolism
Receptors, Virus/*metabolism
SARS-CoV-2/*pathogenicity
A549 Cells ; Adult ; Aged ; Aged, 80 and over ; Angiotensin-Converting Enzyme 2/metabolism ; Antigens, CD/metabolism ; Apoptosis ; Apoptosis Regulatory Proteins/metabolism ; COVID-19/complications ; COVID-19/diagnosis ; Case-Control Studies ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/metabolism ; Female ; Host-Pathogen Interactions ; Humans ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Male ; Middle Aged ; Receptors, Transferrin/metabolism ; SARS-CoV-2/metabolism ; Serine Endopeptidases/metabolism ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe
Tytuł :
Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies.
Autorzy :
Pommerenke C; Department of Bioinformatics and Databases, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Rand U; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Uphoff CC; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Nagel S; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Zaborski M; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Hauer V; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Kaufmann M; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Meyer C; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Denkmann SA; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Riese P; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Eschke K; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Kim Y; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Safranko ZM; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Kurolt IC; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Markotic A; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Cicin-Sain L; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Centre for Individualized Infection Medicine, a Joint Venture of Helmholtz Centre for Infection Research and Medical School Hannover, Hannover, Germany.
Steenpass L; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
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Źródło :
PloS one [PLoS One] 2021 Aug 02; Vol. 16 (8), pp. e0255622. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Virus*/genetics
Receptors, Virus*/metabolism
Virus Internalization*
COVID-19/*virology
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Cell Line, Tumor ; Humans ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism
Czasopismo naukowe
Tytuł :
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.
Autorzy :
Appelman MD; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands.
Wettengel JM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Aug; Vol. 1866 (8), pp. 158960. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Virus Internalization*
Bile Acids and Salts/*metabolism
Hepatitis B virus/*physiology
Organic Anion Transporters, Sodium-Dependent/*metabolism
Symporters/*metabolism
Animals ; Biological Transport ; Humans
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Cellular Entry Is Independent of the ACE2 Cytoplasmic Domain Signaling.
Autorzy :
Karthika T; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Joseph J; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Das VRA; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Nair N; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Charulekha P; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Roji MD; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
Raj VS; Virology Scientific Research (VSR) Laboratory, School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Kerala 695551, India.
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Źródło :
Cells [Cells] 2021 Jul 17; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Virus Internalization*
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*metabolism
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/chemistry ; Animals ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Protein Domains ; Vero Cells
Czasopismo naukowe
Tytuł :
Hypoxia alters the expression of ACE2 and TMPRSS2 SARS-CoV-2 cell entry mediators in hCMEC/D3 brain endothelial cells.
Autorzy :
Imperio GE; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address: .
Lye P; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
Mughis H; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
Hamada H; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
Bloise E; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Lye SJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology and Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Matthews SG; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology and Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
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Źródło :
Microvascular research [Microvasc Res] 2021 Nov; Vol. 138, pp. 104232. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
Angiotensin-Converting Enzyme 2/*metabolism
Brain/*blood supply
COVID-19/*virology
Endothelial Cells/*virology
SARS-CoV-2/*pathogenicity
Serine Endopeptidases/*metabolism
Angiotensin-Converting Enzyme 2/genetics ; COVID-19/enzymology ; Cell Hypoxia ; Cell Line ; Endothelial Cells/enzymology ; Gene Expression Regulation ; Host-Pathogen Interactions ; Humans ; Serine Endopeptidases/genetics
Czasopismo naukowe
Tytuł :
Insights into the Organization of the Poxvirus Multicomponent Entry-Fusion Complex from Proximity Analyses in Living Infected Cells.
Autorzy :
Schin AM; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Diesterbeck US; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Moss B; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
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Źródło :
Journal of virology [J Virol] 2021 Jul 26; Vol. 95 (16), pp. e0085221. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Virus Internalization*
Poxviridae/*physiology
Viral Fusion Proteins/*metabolism
Animals ; Cell Line ; Cytoplasm/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Protein Binding ; Vaccinia virus/genetics ; Vaccinia virus/metabolism ; Vaccinia virus/physiology ; Viral Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.
Autorzy :
Bui LT; Translational Genomics Research Institute, Phoenix, AZ, USA.
Winters NI; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Chung MI; Translational Genomics Research Institute, Phoenix, AZ, USA.
Joseph C; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Gutierrez AJ; Translational Genomics Research Institute, Phoenix, AZ, USA.
Habermann AC; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Adams TS; Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
Schupp JC; Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
Poli S; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Peter LM; Translational Genomics Research Institute, Phoenix, AZ, USA.
Taylor CJ; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Blackburn JB; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Richmond BW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Veterans Affairs Medical Center, Nashville, TN, USA.
Nicholson AG; National Heart and Lung Institute, Imperial College, London, UK.; Department of Histopathology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Rassl D; Pathology Research, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Wallace WA; Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK.; Division of Pathology, Edinburgh University Medical School, Edinburgh, UK.
Rosas IO; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Jenkins RG; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Kaminski N; Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.
Kropski JA; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Veterans Affairs Medical Center, Nashville, TN, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
Banovich NE; Translational Genomics Research Institute, Phoenix, AZ, USA. .
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Corporate Authors :
Human Cell Atlas Lung Biological Network
Źródło :
Nature communications [Nat Commun] 2021 Jul 14; Vol. 12 (1), pp. 4314. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Transcriptome*
Virus Internalization*
Lung Diseases/*genetics
SARS-CoV-2/*physiology
Alveolar Epithelial Cells/metabolism ; Alveolar Epithelial Cells/pathology ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; COVID-19/genetics ; COVID-19/pathology ; Chronic Disease ; Humans ; Idiopathic Pulmonary Fibrosis/genetics ; Idiopathic Pulmonary Fibrosis/pathology ; Immunity, Innate/genetics ; Inflammation/genetics ; Lung/metabolism ; Lung/pathology ; Lung Diseases/pathology ; SARS-CoV-2/pathogenicity ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
Entry, egress and vertical transmission of SARS-CoV-2.
Autorzy :
Zhang H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Zhang H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
Journal of molecular cell biology [J Mol Cell Biol] 2021 Jul 06; Vol. 13 (3), pp. 168-174.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Infectious Disease Transmission, Vertical*
Virus Internalization*
COVID-19/*transmission
SARS-CoV-2/*genetics
COVID-19/genetics ; COVID-19/pathology ; COVID-19/virology ; Female ; Fetus/virology ; Humans ; Lung/pathology ; Lung/virology ; Pandemics ; Pregnancy ; SARS-CoV-2/pathogenicity
Czasopismo naukowe
Tytuł :
Role of host factors in SARS-CoV-2 entry.
Autorzy :
Evans JP; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA; Molecular, Cellular and Developmental Biology Program, The Ohio State University, Columbus, Ohio, USA.
Liu SL; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA; Viruses and Emerging Pathogens Program, Infectious Diseases Institute, The Ohio State University, Columbus, Ohio, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Jul; Vol. 297 (1), pp. 100847. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Virus Internalization*
COVID-19/*metabolism
SARS-CoV-2/*physiology
Animals ; Basigin/genetics ; Basigin/metabolism ; COVID-19/genetics ; COVID-19/virology ; Host-Pathogen Interactions ; Humans ; Lectins, C-Type/genetics ; Lectins, C-Type/metabolism ; Neuropilin-1/genetics ; Neuropilin-1/metabolism ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; SARS-CoV-2/genetics
Czasopismo naukowe

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