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Tytuł:
Interleukin-27-induced HIV-resistant dendritic cells suppress reveres transcription following virus entry in an SPTBN1, autophagy, and YB-1 independent manner.
Autorzy:
Imamichi T; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Chen Q; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Sowrirajan B; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Yang J; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Laverdure S; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Marquez M; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Mele AR; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Watkins C; AIDS monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Adelsberger JW; AIDS monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Higgins J; AIDS monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Sui H; Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Nov 01; Vol. 18 (11), pp. e0287829. Date of Electronic Publication: 2023 Nov 01 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Interleukin-27*
HIV Infections*
HIV-1*
Humans ; Virus Internalization ; Interleukins/metabolism ; Monocytes ; Autophagy/genetics ; DNA/metabolism ; Dendritic Cells/metabolism ; Virus Replication ; Spectrin/metabolism
Czasopismo naukowe
Tytuł:
Pregnancy-induced differential expression of SARS-CoV-2 and influenza a viral entry factors in the lower respiratory tract.
Autorzy:
Giri T; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States of America.
Panda S; Department of Pathology, Washington University School of Medicine, St. Louis, MO, United States of America.
Palanisamy A; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Jul 12; Vol. 18 (7), pp. e0281033. Date of Electronic Publication: 2023 Jul 12 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Influenza, Human*
Influenza A virus*
Female ; Pregnancy ; Animals ; Rats ; Humans ; SARS-CoV-2 ; Virus Internalization ; Respiratory System
Czasopismo naukowe
Tytuł:
Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction.
Autorzy:
Mahindra A; School of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Tejeda G; Institute of Molecular Cell & Systems Biology, School of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Rossi M; Institute of Molecular Cell & Systems Biology, School of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Janha O; Institute of Molecular Cell & Systems Biology, School of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Herbert I; MRC Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.
Morris C; School of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Morgan DC; School of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Beattie W; Institute of Cardiovascular and Medical Sciences, Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Montezano AC; Institute of Cardiovascular and Medical Sciences, Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Hudson B; Institute of Molecular Cell & Systems Biology, School of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Tobin AB; Institute of Molecular Cell & Systems Biology, School of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Bhella D; MRC Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.
Touyz RM; Institute of Cardiovascular and Medical Sciences, Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Jamieson AG; School of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Baillie GS; Institute of Cardiovascular and Medical Sciences, Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Blair CM; Institute of Cardiovascular and Medical Sciences, Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło:
PloS one [PLoS One] 2021 Nov 18; Vol. 16 (11), pp. e0260283. Date of Electronic Publication: 2021 Nov 18 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Internalization*
Angiotensin-Converting Enzyme 2/*immunology
Antiviral Agents/*pharmacology
Peptides/*pharmacology
Protein Binding/*drug effects
Spike Glycoprotein, Coronavirus/*immunology
A549 Cells ; Humans ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Tytuł:
Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies.
Autorzy:
Pommerenke C; Department of Bioinformatics and Databases, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Rand U; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Uphoff CC; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Nagel S; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Zaborski M; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Hauer V; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Kaufmann M; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Meyer C; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Denkmann SA; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Riese P; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Eschke K; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Kim Y; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Safranko ZM; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Kurolt IC; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Markotic A; Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.
Cicin-Sain L; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Centre for Individualized Infection Medicine, a Joint Venture of Helmholtz Centre for Infection Research and Medical School Hannover, Hannover, Germany.
Steenpass L; Department of Human and Animal Cell Lines, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
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Źródło:
PloS one [PLoS One] 2021 Aug 02; Vol. 16 (8), pp. e0255622. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Virus*/genetics
Receptors, Virus*/metabolism
Virus Internalization*
COVID-19/*virology
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Cell Line, Tumor ; Humans ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism
Czasopismo naukowe
Tytuł:
Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection.
Autorzy:
Qiao Y; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.; Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States of America.
Wotring JW; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States of America.
Zhang CJ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States of America.
Jiang X; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.
Xiao L; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.
Watt A; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Gattis D; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Scandalis E; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Freier S; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Zheng Y; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.
Pretto CD; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States of America.
Ellison SJ; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.
Swayze EE; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Guo S; Ionis Pharmaceuticals, Carlsbad, CA, United States of America.
Sexton JZ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, United States of America.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States of America.; Center for Drug Repurposing, University of Michigan, Ann Arbor, MI, United States of America.; Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, United States of America.
Chinnaiyan AM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, United States of America.; Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States of America.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, United States of America.; Department of Urology, University of Michigan, Ann Arbor, MI, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Feb 03; Vol. 18 (2), pp. e0281281. Date of Electronic Publication: 2023 Feb 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*
Humans ; Angiotensin-Converting Enzyme 2/metabolism ; Oligonucleotides, Antisense/pharmacology ; Oligonucleotides, Antisense/therapeutic use ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Virus Internalization
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
SARS-CoV-2 replicates and displays oncolytic properties in clear cell and papillary renal cell carcinoma.
Autorzy:
Choong OK; Department of Laboratory Medicine, Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jakobsson R; Department of Laboratory Medicine, Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery and Urology, Skaraborg Hospital, Skövde, Sweden.
Bergdahl AG; Department of Urology, Institute of Clinical Science, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Brunet S; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Kärmander A; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Waldenström J; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Arvidsson Y; Department of Laboratory Medicine, Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Altiparmak G; Department of Laboratory Medicine, Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Nilsson JA; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery, Sahlgrenska Center for Cancer Research, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Harry Perkins Institute of Medical Research, University of Western Australia, Perth, Australia.
Karlsson J; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery, Sahlgrenska Center for Cancer Research, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Harry Perkins Institute of Medical Research, University of Western Australia, Perth, Australia.
Nyström K; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Johansson ME; Department of Laboratory Medicine, Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
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Źródło:
PloS one [PLoS One] 2023 Jan 03; Vol. 18 (1), pp. e0279578. Date of Electronic Publication: 2023 Jan 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/therapy
Carcinoma, Renal Cell*/metabolism
COVID-19*
Kidney Neoplasms*/metabolism
Humans ; SARS-CoV-2/metabolism ; Peptidyl-Dipeptidase A/metabolism ; Virus Internalization
Czasopismo naukowe
Tytuł:
Genetic variants determine intrafamilial variability of SARS-CoV-2 clinical outcomes in 19 Italian families.
Autorzy:
Azzarà A; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Cassano I; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.; Dipartimento di Scienze della Vita e di Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italia.
Paccagnella E; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Tirindelli MC; Transfusion Medicine and Cellular Therapy Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Nobile C; Transfusion Medicine and Cellular Therapy Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Schittone V; Hematology and Stem Cell Transplant Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Lintas C; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.; Operative Research Unit of Medical Genetics, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Sacco R; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.; Operative Research Unit of Neurodevelopmental Disorders/Child Neuropsychiatry, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Gurrieri F; Research Unit of Medical Genetics, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.; Operative Research Unit of Medical Genetics, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
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Źródło:
PloS one [PLoS One] 2022 Oct 13; Vol. 17 (10), pp. e0275988. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/genetics
Virus Diseases*
Humans ; Polymorphism, Single Nucleotide ; SARS-CoV-2/genetics ; Virus Internalization
Czasopismo naukowe
Tytuł:
Characterizing the cellular attachment receptor for Langat virus.
Autorzy:
Rodrigues R; Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
Danskog K; Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
Överby AK; Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
Arnberg N; Virology, Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
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Źródło:
PloS one [PLoS One] 2019 Jun 04; Vol. 14 (6), pp. e0217359. Date of Electronic Publication: 2019 Jun 04 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Attachment*
Virus Internalization*
Encephalitis Viruses, Tick-Borne/*metabolism
Encephalitis, Tick-Borne/*metabolism
Membrane Proteins/*metabolism
A549 Cells ; Humans
Czasopismo naukowe
Tytuł:
Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.
Autorzy:
Plegge T; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
Spiegel M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Institute of Microbiology and Virology, Brandenburg Medical School Theodor Fontane, Senftenberg, Germany.
Krüger N; Institute of Virology, University of Veterinary Medicine Hannover, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, Hannover, Germany.
Nehlmeier I; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.
Winkler M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.
González Hernández M; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
Pöhlmann S; Infection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany.
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Źródło:
PloS one [PLoS One] 2019 Apr 11; Vol. 14 (4), pp. e0214968. Date of Electronic Publication: 2019 Apr 11 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endosomes*/enzymology
Endosomes*/genetics
Endosomes*/virology
Virus Internalization*
Aspartic Acid Endopeptidases/*metabolism
Cathepsin B/*metabolism
Cathepsin L/*metabolism
Glycoproteins/*metabolism
Viral Envelope Proteins/*metabolism
Animals ; Aspartic Acid Endopeptidases/antagonists & inhibitors ; Aspartic Acid Endopeptidases/genetics ; COS Cells ; Cathepsin B/antagonists & inhibitors ; Cathepsin B/genetics ; Cathepsin L/antagonists & inhibitors ; Cathepsin L/genetics ; Chlorocebus aethiops ; Ebolavirus/genetics ; Glycoproteins/genetics ; HEK293 Cells ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Vero Cells ; Viral Envelope Proteins/genetics
Czasopismo naukowe
Tytuł:
Effect of 17β-estradiol on the daily pattern of ACE2, ADAM17, TMPRSS2 and estradiol receptor transcription in the lungs and colon of male rats.
Autorzy:
Herichová I; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Jendrisková S; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Pidíková P; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Kršková L; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Olexová L; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Morová M; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Stebelová K; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
Štefánik P; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic.
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Źródło:
PloS one [PLoS One] 2022 Jun 28; Vol. 17 (6), pp. e0270609. Date of Electronic Publication: 2022 Jun 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ADAM17 Protein*/genetics
Angiotensin-Converting Enzyme 2*/genetics
COVID-19*/virology
Colon*/drug effects
Colon*/metabolism
Estradiol*/pharmacology
Lung*/metabolism
Receptors, Estradiol*/genetics
Receptors, Estradiol*/metabolism
COVID-19 Drug Treatment*
Animals ; Female ; Male ; Peptidyl-Dipeptidase A/metabolism ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Rats ; Rats, Wistar ; SARS-CoV-2/physiology ; Serine Endopeptidases/genetics ; Transcription, Genetic/drug effects ; Virus Internalization
Czasopismo naukowe
Tytuł:
Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry.
Autorzy:
Bohlin J; Department of Method Development and analytics, Norwegian Institute of Public Health, Oslo, Norway.; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Page CM; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Department of Mathematics, University of Oslo, Oslo, Norway.
Lee Y; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Pettersson JH; Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences and School of Medical Sciences, the University of Sydney, Sydney, New South Wales, Australia.; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, University of Uppsala, Uppsala, Sweden.
Jugessur A; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Magnus P; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Håberg SE; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
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Źródło:
PloS one [PLoS One] 2022 Jun 09; Vol. 17 (6), pp. e0269105. Date of Electronic Publication: 2022 Jun 09 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/genetics
SARS-CoV-2*/genetics
Child ; Cohort Studies ; CpG Islands ; DNA Methylation ; Epigenesis, Genetic ; Humans ; Male ; Virus Internalization
Czasopismo naukowe
Tytuł:
Ex vivo HIV entry into blood CD4+ T cells does not predict heterosexual HIV acquisition in women.
Autorzy:
Joag V; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Sivro A; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.; Department of Microbiology, University of Winnipeg, Manitoba, Canada.
Yende-Zuma N; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
Imam H; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Samsunder N; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
Abdool Karim Q; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
Abdool Karim S; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
McKinnon L; Centre for the AIDS Program of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.; Department of Microbiology, University of Winnipeg, Manitoba, Canada.
Kaul R; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Ontario, Canada.
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Źródło:
PloS one [PLoS One] 2018 Jul 09; Vol. 13 (7), pp. e0200359. Date of Electronic Publication: 2018 Jul 09 (Print Publication: 2018).
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Internalization*
CD4-Positive T-Lymphocytes/*virology
HIV Infections/*blood
HIV Infections/*virology
Adult ; Case-Control Studies ; Disease Susceptibility/virology ; Female ; HIV/physiology ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Heterosexuality ; Humans ; In Vitro Techniques ; Prognosis ; Retrospective Studies ; Risk ; Single-Blind Method ; Young Adult
Czasopismo naukowe
Tytuł:
Quantitative membrane proteomics reveals a role for tetraspanin enriched microdomains during entry of human cytomegalovirus.
Autorzy:
Viswanathan K; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America.
Verweij MC; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America.
John N; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America.
Malouli D; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America.
Früh K; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Nov 09; Vol. 12 (11), pp. e0187899. Date of Electronic Publication: 2017 Nov 09 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Virus Internalization*/drug effects
Cell Membrane/*metabolism
Cytomegalovirus/*physiology
Fibroblasts/*virology
Proteomics/*methods
Tetraspanins/*metabolism
Cell Line ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Gene Expression Regulation ; Humans ; Integrins/chemistry ; Integrins/metabolism ; Isotope Labeling ; Protein Domains/drug effects ; Tetraspanins/chemistry ; Tetraspanins/drug effects ; beta-Cyclodextrins/pharmacology
Czasopismo naukowe
Tytuł:
The inhibitory effects of toothpaste and mouthwash ingredients on the interaction between the SARS-CoV-2 spike protein and ACE2, and the protease activity of TMPRSS2 in vitro.
Autorzy:
Tateyama-Makino R; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Abe-Yutori M; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Iwamoto T; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Tsutsumi K; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Tsuji M; Institute of Molecular Function, Misato-shi, Saitama, Japan.
Morishita S; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Kurita K; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Yamamoto Y; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Nishinaga E; Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan.
Tsukinoki K; Division of Environmental Pathology, Department of Oral Science, Kanagawa Dental University, Yokosuka, Kanagawa, Japan.
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Źródło:
PloS one [PLoS One] 2021 Sep 17; Vol. 16 (9), pp. e0257705. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19/*prevention & control
Mouthwashes/*pharmacology
Oral Hygiene/*methods
SARS-CoV-2/*drug effects
Toothpastes/*pharmacology
Virus Internalization/*drug effects
Angiotensin-Converting Enzyme 2/immunology ; Humans ; Serine Endopeptidases/immunology ; Spike Glycoprotein, Coronavirus/immunology
Czasopismo naukowe
Tytuł:
Genomics-guided identification of potential modulators of SARS-CoV-2 entry proteases, TMPRSS2 and Cathepsins B/L.
Autorzy:
Prasad K; Amity Institute of Neuropsychology & Neurosciences (AINN), Amity University, Noida, UP, India.
AlOmar SY; Department of College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Almuqri EA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Rudayni HA; Biology Department, College of Science, Imam Muhammad bin Saud Islamic University, Riyadh, Kingdom of Saudi Arabia.
Kumar V; Amity Institute of Neuropsychology & Neurosciences (AINN), Amity University, Noida, UP, India.
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Źródło:
PloS one [PLoS One] 2021 Aug 18; Vol. 16 (8), pp. e0256141. Date of Electronic Publication: 2021 Aug 18 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cathepsin B/*genetics
Cathepsin L/*genetics
Estradiol/*pharmacology
Genomics/*methods
SARS-CoV-2/*physiology
Serine Endopeptidases/*genetics
Tretinoin/*pharmacology
Cathepsin B/chemistry ; Cathepsin L/chemistry ; Databases, Genetic ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Regulatory Networks/drug effects ; Host-Pathogen Interactions ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Protein Conformation ; Protein Interaction Maps/drug effects ; SARS-CoV-2/drug effects ; Serine Endopeptidases/chemistry ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł:
SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19.
Autorzy:
Nader D; Cardiovascular Infection Research Group, School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Fletcher N; School of Veterinary Medicine, Veterinary Science Centre, University College Dublin, Belfield, Dublin 4, Ireland.
Curley GF; Department of Anaesthesia and Critical Care Medicine, RCSI University of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
Kerrigan SW; Cardiovascular Infection Research Group, School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
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Źródło:
PloS one [PLoS One] 2021 Jun 23; Vol. 16 (6), pp. e0253347. Date of Electronic Publication: 2021 Jun 23 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelium, Vascular/*virology
Integrin alphaVbeta3/*metabolism
SARS-CoV-2/*pathogenicity
Snake Venoms/*pharmacology
Antigens, CD/metabolism ; Binding Sites ; COVID-19/metabolism ; COVID-19/physiopathology ; Caco-2 Cells ; Cadherins/metabolism ; Computer Simulation ; Endothelium, Vascular/cytology ; Endothelium, Vascular/physiopathology ; Host-Pathogen Interactions/drug effects ; Humans ; Integrin alphaVbeta3/chemistry ; Models, Molecular ; Mutation ; Permeability ; SARS-CoV-2/drug effects ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Virus Internalization
Czasopismo naukowe
Tytuł:
Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions.
Autorzy:
Goc A; Department of Infectious Diseases, Dr. Rath Research Institute, San Jose, California, United States of America.
Sumera W; Department of Infectious Diseases, Dr. Rath Research Institute, San Jose, California, United States of America.
Rath M; Department of Infectious Diseases, Dr. Rath Research Institute, San Jose, California, United States of America.
Niedzwiecki A; Department of Infectious Diseases, Dr. Rath Research Institute, San Jose, California, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jun 17; Vol. 16 (6), pp. e0253489. Date of Electronic Publication: 2021 Jun 17 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*prevention & control
Polyphenols/*pharmacology
SARS-CoV-2/*drug effects
Spike Glycoprotein, Coronavirus/*metabolism
Virus Internalization/*drug effects
A549 Cells ; Benzopyrans/pharmacology ; Biflavonoids/pharmacology ; COVID-19/virology ; Catechin/analogs & derivatives ; Catechin/pharmacology ; Cell Survival/drug effects ; Curcumin/pharmacology ; Humans ; Protein Binding/drug effects ; SARS-CoV-2/metabolism ; SARS-CoV-2/physiology ; Virion/drug effects ; Virion/metabolism ; Virion/physiology ; Virus Attachment/drug effects
Czasopismo naukowe
Tytuł:
Identification and evaluation of the inhibitory effect of Prunella vulgaris extract on SARS-coronavirus 2 virus entry.
Autorzy:
Ao Z; Department of Medical Microbiology and Infectious Diseases, Laboratory of Molecular Human Retrovirology, Rady Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada.
Chan M; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Ouyang MJ; Department of Medical Microbiology and Infectious Diseases, Laboratory of Molecular Human Retrovirology, Rady Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada.
Olukitibi TA; Department of Medical Microbiology and Infectious Diseases, Laboratory of Molecular Human Retrovirology, Rady Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada.
Mahmoudi M; Department of Medical Microbiology and Infectious Diseases, Laboratory of Molecular Human Retrovirology, Rady Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada.
Kobasa D; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Yao X; Department of Medical Microbiology and Infectious Diseases, Laboratory of Molecular Human Retrovirology, Rady Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada.
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Źródło:
PloS one [PLoS One] 2021 Jun 09; Vol. 16 (6), pp. e0251649. Date of Electronic Publication: 2021 Jun 09 (Print Publication: 2021).
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19 Drug Treatment*
COVID-19/*virology
Plant Extracts/*pharmacology
Prunella/*chemistry
SARS-CoV-2/*drug effects
Suramin/*pharmacology
Virus Internalization/*drug effects
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antibodies, Neutralizing/pharmacology ; COVID-19/genetics ; COVID-19/metabolism ; Cell Line ; Chlorocebus aethiops ; Drug Therapy, Combination ; Humans ; Mutation ; Protein Binding ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe
Tytuł:
Computational designing of a peptide that potentially blocks the entry of SARS-CoV, SARS-CoV-2 and MERS-CoV.
Autorzy:
V K P; National Institute of Technology, Calicut, Kerala, India.
Rath SP; MIMS Research Foundation, Calicut, Kerala, India.
Abraham P; MIMS Research Foundation, Calicut, Kerala, India.
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Źródło:
PloS one [PLoS One] 2021 May 18; Vol. 16 (5), pp. e0251913. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Middle East Respiratory Syndrome Coronavirus/*physiology
Peptides/*pharmacology
Severe acute respiratory syndrome-related coronavirus/*physiology
SARS-CoV-2/*physiology
Virus Internalization/*drug effects
Amino Acid Sequence ; Binding Sites ; Humans ; Hydrogen Bonding ; Middle East Respiratory Syndrome Coronavirus/metabolism ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Peptides/chemistry ; Peptides/metabolism ; Protein Binding ; Receptors, Virus/chemistry ; Receptors, Virus/metabolism ; Severe acute respiratory syndrome-related coronavirus/metabolism ; SARS-CoV-2/metabolism ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe

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