Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""INTRACELLULAR calcium"" wg kryterium: Temat


Tytuł :
A store-operated Ca -entry in Trypanosoma equiperdum: Physiological evidences of its presence.
Autorzy :
Pérez-Gordones MC; Instituto de Biología Experimental (IBE), Universidad Central de Venezuela (UCV), Caracas, Venezuela.
Ramírez-Iglesias JR; Group of Neglected and Emerging Diseases, Epidemiology and Biodiversity, Health Sciences Faculty, Universidad Internacional SEK (UISEK), Quito, Ecuador.
Benaim G; Instituto de Biología Experimental (IBE), Universidad Central de Venezuela (UCV), Caracas, Venezuela; Instituto de Estudios Avanzados (IDEA), Caracas, Venezuela.
Mendoza M; Centro de Estudios Biomédicos y Veterinarios, Instituto de Estudios Científicos y Tecnológicos (IDECYT), Universidad Nacional Experimental Simón Rodríguez, Caracas, Venezuela. Electronic address: .
Pokaż więcej
Źródło :
Molecular and biochemical parasitology [Mol Biochem Parasitol] 2021 Jul; Vol. 244, pp. 111394. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Intracellular Calcium-Sensing Proteins/*metabolism
Protozoan Proteins/*metabolism
Transient Receptor Potential Channels/*metabolism
Trypanosoma/*metabolism
Animals ; Boron Compounds/pharmacology ; Calcium Chelating Agents/chemistry ; Computational Biology/methods ; Enzyme Inhibitors/pharmacology ; Fluorescent Dyes/chemistry ; Fura-2/chemistry ; Gene Expression ; Homeostasis/genetics ; Hydroquinones/pharmacology ; Intracellular Calcium-Sensing Proteins/genetics ; Manganese/metabolism ; Protozoan Proteins/genetics ; Thapsigargin/pharmacology ; Transient Receptor Potential Channels/genetics ; Trypanosoma/drug effects ; Trypanosoma/genetics ; Trypanosomiasis/parasitology
Czasopismo naukowe
Tytuł :
Temporal modulation of calcium sensing in hematopoietic stem cells is crucial for proper stem cell expansion and engraftment.
Autorzy :
Uslu M; Regenerative Biology Research Laboratory, Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.; Graduate School of Natural and Applied Sciences, Yeditepe University, Istanbul, Turkey.
Albayrak E; Regenerative Biology Research Laboratory, Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.; Graduate School of Natural and Applied Sciences, Yeditepe University, Istanbul, Turkey.
Kocabaş F; Regenerative Biology Research Laboratory, Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.; Graduate School of Natural and Applied Sciences, Yeditepe University, Istanbul, Turkey.
Pokaż więcej
Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Dec; Vol. 235 (12), pp. 9644-9666. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Intracellular Calcium-Sensing Proteins/*genetics
Membrane Proteins/*genetics
Receptors, CXCR4/*genetics
Receptors, Calcium-Sensing/*genetics
Animals ; Boron Compounds/pharmacology ; Calcium Signaling/drug effects ; Calcium Signaling/genetics ; Cell Adhesion Molecules/genetics ; Cell Cycle/genetics ; Cell Differentiation/drug effects ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Coculture Techniques ; Fetal Blood/metabolism ; Gene Expression Regulation, Developmental/drug effects ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/metabolism ; Humans ; Imidazoles/pharmacology ; Intracellular Calcium-Sensing Proteins/antagonists & inhibitors ; Membrane Proteins/antagonists & inhibitors ; Mice
Czasopismo naukowe
Tytuł :
Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity.
Autorzy :
Chernorudskiy A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Varone E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Colombo SF; Institute of Neuroscience, Consiglio Nazionale delle Ricerche and BIOMETRA Department, Università degli Studi di Milano, 20129 Milan, Italy.
Fumagalli S; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Cagnotto A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Cattaneo A; Proteomics/MS Facility, Cogentech SRL Benefit Corporation, 20139 Milan, Italy.
Briens M; Architecture et Réactivité de l'ARN, CNRS, Université de Strasbourg, 67084 Strasbourg, France.
Baltzinger M; Architecture et Réactivité de l'ARN, CNRS, Université de Strasbourg, 67084 Strasbourg, France.
Kuhn L; Architecture et Réactivité de l'ARN, CNRS, Université de Strasbourg, 67084 Strasbourg, France.
Bachi A; IFOM-FIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Berardi A; Biomolecular NMR Unit, IRCCS Ospedale S. Raffaele, 20132 Milan, Italy.
Salmona M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Musco G; Biomolecular NMR Unit, IRCCS Ospedale S. Raffaele, 20132 Milan, Italy.
Borgese N; Institute of Neuroscience, Consiglio Nazionale delle Ricerche and BIOMETRA Department, Università degli Studi di Milano, 20129 Milan, Italy.
Lescure A; Architecture et Réactivité de l'ARN, CNRS, Université de Strasbourg, 67084 Strasbourg, France.
Zito E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21288-21298. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Endoplasmic Reticulum/*metabolism
Intracellular Calcium-Sensing Proteins/*metabolism
Muscle Proteins/*metabolism
Selenoproteins/*metabolism
HeLa Cells ; Humans ; Intracellular Calcium-Sensing Proteins/genetics ; Muscle Proteins/genetics ; Oxidation-Reduction ; Selenoproteins/genetics
Czasopismo naukowe
Tytuł :
Ca Influx Channel Inhibitor SARAF Protects Mice From Acute Pancreatitis.
Autorzy :
Son A; Epithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Ahuja M; Epithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Schwartz DM; Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Varga A; HAS-USZ Momentum Epithelial Cell Signaling and Secretion Research Group, First Department of Medicine, University of Szeged, Szeged, Hungary.
Swaim W; NIDCR imaging core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Kang N; Department of Oral Biology, BK 21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea.
Maleth J; HAS-USZ Momentum Epithelial Cell Signaling and Secretion Research Group, First Department of Medicine, University of Szeged, Szeged, Hungary.
Shin DM; Department of Oral Biology, BK 21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea. Electronic address: .
Muallem S; Epithelial Signaling and Transport Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland. Electronic address: .
Pokaż więcej
Źródło :
Gastroenterology [Gastroenterology] 2019 Dec; Vol. 157 (6), pp. 1660-1672.e2. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Intracellular Calcium-Sensing Proteins/*metabolism
Membrane Proteins/*metabolism
Neoplasm Proteins/*metabolism
Pancreas/*pathology
Pancreatitis/*pathology
Stromal Interaction Molecule 1/*metabolism
Acinar Cells/pathology ; Animals ; Ceruletide/toxicity ; Disease Models, Animal ; HEK293 Cells ; Humans ; Intracellular Calcium-Sensing Proteins/genetics ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Pancreas/cytology ; Pancreatitis/blood ; Pancreatitis/chemically induced ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Transmembrane protein 66 attenuates neointimal hyperplasia after carotid artery injury by SOCE inactivation.
Autorzy :
Yang J; Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, Sichuan 610083, P.R. China.
Li S; Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, Sichuan 610083, P.R. China.
Wang Q; Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, Sichuan 610083, P.R. China.
Yang D; Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, Sichuan 610083, P.R. China.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2019 Aug; Vol. 20 (2), pp. 1436-1442. Date of Electronic Publication: 2019 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium/*metabolism
Calcium-Binding Proteins/*metabolism
Carotid Artery Injuries/*genetics
Hyperplasia/*genetics
Intracellular Calcium-Sensing Proteins/*genetics
Membrane Proteins/*metabolism
Neointima/*genetics
Angioplasty, Balloon/adverse effects ; Animals ; Becaplermin/pharmacology ; Calcium Signaling ; Calcium-Binding Proteins/genetics ; Carotid Arteries/metabolism ; Carotid Arteries/pathology ; Carotid Artery Injuries/etiology ; Carotid Artery Injuries/metabolism ; Carotid Artery Injuries/pathology ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Disease Models, Animal ; Gene Expression Regulation ; Hyperplasia/etiology ; Hyperplasia/metabolism ; Hyperplasia/pathology ; Intracellular Calcium-Sensing Proteins/metabolism ; Ion Transport ; Male ; Membrane Proteins/genetics ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Neointima/etiology ; Neointima/metabolism ; Neointima/pathology ; ORAI1 Protein/genetics ; ORAI1 Protein/metabolism ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism
Czasopismo naukowe
Tytuł :
SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped β-Sandwich Fold Important for SOCE Modulation.
Autorzy :
Kimberlin CR; Cardiovascular Research Institute, University of California, San Francisco, CA 94148, USA.
Meshcheriakova A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Palty R; Rappaport Family School of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
Raveh A; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Karbat I; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Reuveny E; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: .
Minor DL Jr; Cardiovascular Research Institute, University of California, San Francisco, CA 94148, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Fancisco, CA 94158, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: .
Pokaż więcej
Źródło :
Journal of molecular biology [J Mol Biol] 2019 Jul 12; Vol. 431 (15), pp. 2869-2883. Date of Electronic Publication: 2019 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Calcium/*metabolism
Intracellular Calcium-Sensing Proteins/*metabolism
Membrane Proteins/*metabolism
Calcium Signaling ; Crystallography, X-Ray ; HEK293 Cells ; Humans ; Intracellular Calcium-Sensing Proteins/chemistry ; Membrane Proteins/chemistry ; Models, Molecular ; Protein Conformation, beta-Strand ; Protein Domains ; Protein Folding ; Protein Multimerization
Czasopismo naukowe
Tytuł :
Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3.
Autorzy :
Lin T; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Luo W; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Li Z; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Zhang L; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Zheng X; Mathematical Engineering Academy of Chinese Medicine; Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
Mai L; Mathematical Engineering Academy of Chinese Medicine; Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
Yang W; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Guan G; Department of obstetrics and gynecology, the first affiliated hospital of Sun Yat-sen University, Guangzhou, P. R. China.
Su Z; Mathematical Engineering Academy of Chinese Medicine; Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
Liu P; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China.
Li Z; Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences; National and Local United Engineering Lab of Druggability and New Drugs Evaluation; Guangdong Engineering Laboratoty of Druggability and New Drug Evaluation; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, P. R. China. Electronic address: .
Xie Y; Mathematical Engineering Academy of Chinese Medicine; Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China. Electronic address: .
Pokaż więcej
Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Dec; Vol. 79, pp. 153350. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelium, Vascular/*drug effects
Intracellular Calcium-Sensing Proteins/*metabolism
Kaempferols/*pharmacology
Membrane Proteins/*metabolism
NFATC Transcription Factors/*metabolism
Neoplasm Proteins/*metabolism
Orchidaceae/*chemistry
Stromal Interaction Molecule 1/*metabolism
Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Endothelium, Vascular/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Kaempferols/isolation & purification ; Lipopolysaccharides/pharmacology ; Pandemics ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł :
Bis-γ-carbolines as new potential multitarget agents for Alzheimer's disease.
Autorzy :
Makhaeva, Galina F. (AUTHOR)
Shevtsova, Elena F. (AUTHOR)
Aksinenko, Alexey Y. (AUTHOR)
Kovaleva, Nadezhda V. (AUTHOR)
Boltneva, Natalia P. (AUTHOR)
Lushchekina, Sofya V. (AUTHOR)
Rudakova, Еlena V. (AUTHOR)
Pushkareva, Elena A. (AUTHOR)
Serkova, Tatyana P. (AUTHOR)
Dubova, Lyudmila G. (AUTHOR)
Shevtsov, Pavel N. (AUTHOR)
Sokolov, Vladimir B. (AUTHOR)
Radchenko, Eugene V. (AUTHOR)
Palyulin, Vladimir A. (AUTHOR)
Bachurin, Sergey O. (AUTHOR)
Richardson, Rudy J. (AUTHOR)
Pokaż więcej
Źródło :
Pure & Applied Chemistry. Jul2020, Vol. 92 Issue 7, p1057-1080. 24p.
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies