Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""ION channels"" wg kryterium: Temat


Tytuł :
Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation.
Autorzy :
Lefebvre SN; Institut Pasteur, Université de Paris, CNRS UMR 3571,Channel-Receptors Unit, Paris, France.; Sorbonne Université, Collège doctoral, Paris, France.
Taly A; Institut de Biologie Physico-chimique, Fondation Edmond de Rothschild, PSL Research University, Paris, France.; Laboratoire de Biochimie Théorique, CNRS, Université de Paris, UPR 9080, Paris, France.
Menny A; Institut Pasteur, Université de Paris, CNRS UMR 3571,Channel-Receptors Unit, Paris, France.; Sorbonne Université, Collège doctoral, Paris, France.
Medjebeur K; Institut Pasteur, Université de Paris, CNRS UMR 3571,Channel-Receptors Unit, Paris, France.
Corringer PJ; Institut Pasteur, Université de Paris, CNRS UMR 3571,Channel-Receptors Unit, Paris, France.
Pokaż więcej
Źródło :
ELife [Elife] 2021 Sep 30; Vol. 10. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Mutational Analysis*
Ion Channel Gating*
Mutation*
Bacterial Proteins/*metabolism
Cyanobacteria/*metabolism
Ligand-Gated Ion Channels/*metabolism
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Cyanobacteria/genetics ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Ligand-Gated Ion Channels/chemistry ; Ligand-Gated Ion Channels/genetics ; Models, Biological ; Molecular Docking Simulation ; Protein Conformation ; Structure-Activity Relationship ; Time Factors
SCR Organism :
Gloeobacter violaceus
Czasopismo naukowe
Tytuł :
Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Autorzy :
Deneka D; Department of Biochemistry University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
Rutz S; Department of Biochemistry University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
Hutter CAJ; Institute of Medical Microbiology University of Zurich, Gloriastrasse 28/30, CH-8006, Zurich, Switzerland.
Seeger MA; Institute of Medical Microbiology University of Zurich, Gloriastrasse 28/30, CH-8006, Zurich, Switzerland.
Sawicka M; Department of Biochemistry University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. .
Dutzler R; Department of Biochemistry University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Sep 14; Vol. 12 (1), pp. 5435. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epitopes/*chemistry
Ion Channels/*chemistry
Membrane Proteins/*chemistry
Single-Domain Antibodies/*chemistry
Allosteric Regulation ; Allosteric Site ; Amino Acid Sequence ; Animals ; Cloning, Molecular ; Epitopes/genetics ; Epitopes/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Ion Channels/genetics ; Ion Channels/metabolism ; Ion Transport ; Kinetics ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Models, Molecular ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Single-Domain Antibodies/genetics ; Single-Domain Antibodies/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology.
Autorzy :
Braun N; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Friis S; Nanion Technologies GmbH, Munich, Germany.
Ihling C; Department of Pharmaceutical Chemistry & Bioanalytics, Center for Structural Mass Spectrometry, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Sinz A; Department of Pharmaceutical Chemistry & Bioanalytics, Center for Structural Mass Spectrometry, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Andersen J; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Pless SA; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Pokaż więcej
Źródło :
PLoS biology [PLoS Biol] 2021 Sep 07; Vol. 19 (9), pp. e3001321. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acid Sensing Ion Channels/*chemistry
Acid Sensing Ion Channels/*pharmacology
Amino Acids/*chemistry
Acid Sensing Ion Channels/genetics ; HEK293 Cells ; Humans ; Peptides/chemistry ; Spider Venoms/chemistry ; Transfection
Czasopismo naukowe
Tytuł :
C-Jun N-Terminal Kinase Post-Translational Regulation of Pain-Related Acid-Sensing Ion Channels 1b and 3.
Autorzy :
Verkest C; Université Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire Laboratoire d'Excellence Canaux Ioniques d'Intérêt Thérapeutique, Fédération Hospitalo-Universitaire InovPain, 06000 Nice, France .
Diochot S; Université Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire Laboratoire d'Excellence Canaux Ioniques d'Intérêt Thérapeutique, Fédération Hospitalo-Universitaire InovPain, 06000 Nice, France.
Lingueglia E; Université Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire Laboratoire d'Excellence Canaux Ioniques d'Intérêt Thérapeutique, Fédération Hospitalo-Universitaire InovPain, 06000 Nice, France.
Baron A; Université Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire Laboratoire d'Excellence Canaux Ioniques d'Intérêt Thérapeutique, Fédération Hospitalo-Universitaire InovPain, 06000 Nice, France .
Pokaż więcej
Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Oct 20; Vol. 41 (42), pp. 8673-8685. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acid Sensing Ion Channels/*metabolism
JNK Mitogen-Activated Protein Kinases/*metabolism
Pain/*metabolism
Protein Processing, Post-Translational/*physiology
Acid Sensing Ion Channels/genetics ; Amino Acid Sequence ; Animals ; Anisomycin/pharmacology ; Anthracenes/pharmacology ; Anthracenes/therapeutic use ; Cells, Cultured ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; HEK293 Cells ; Humans ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; JNK Mitogen-Activated Protein Kinases/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Pain/drug therapy ; Pain/genetics ; Protein Processing, Post-Translational/drug effects ; Protein Synthesis Inhibitors/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs.
Autorzy :
Sheikh ZP; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Wulf M; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Friis S; Nanion Technologies, Munich, Germany.
Althaus M; School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UK.
Lynagh T; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Pless SA; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Oct 04; Vol. 153 (10). Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acid Sensing Ion Channels*
Epithelial Sodium Channels*
Ions ; Potassium/metabolism ; Sodium/metabolism
Czasopismo naukowe
Tytuł :
ASIC2 Synergizes with TRPV1 in the Mechano-Electrical Transduction of Arterial Baroreceptors.
Autorzy :
Yan X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Zhang S; Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Zhao H; Yanjing Medical College, Capital Medical University, Beijing, 101300, China.
Liu P; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Huang H; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Niu W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Wang W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. .; Beijing Laboratory for Cardiovascular Precision Medicine, Capital Medical University, Beijing, 100069, China. .
Zhang C; Department of Neurobiology, School of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, 100069, China. .
Pokaż więcej
Źródło :
Neuroscience bulletin [Neurosci Bull] 2021 Oct; Vol. 37 (10), pp. 1381-1396. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Acid Sensing Ion Channels*/physiology
Pressoreceptors*/physiology
TRPV Cation Channels/*physiology
Animals ; HEK293 Cells ; Humans ; Rats
Czasopismo naukowe
Tytuł :
Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis.
Autorzy :
Pang H; Department of Biophysics, School of Physics Science, The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, Tianjin, PR China.
Li J; Biology Laboratory, Tianjin High School, Tianjin, PR China.
Wang Y; Laboratory Animal Center, College of Life Sciences, Nankai University, Tianjin, PR China.
Su X; Laboratory Animal Center, College of Life Sciences, Nankai University, Tianjin, PR China.
Gao Y; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases, Institute of Hepatobiliary Disease, Nankai University Affiliated Third Center Hospital, Tianjin, PR China. Electronic address: .
Li SJ; Department of Biophysics, School of Physics Science, The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, Tianjin, PR China; Biomedical Research Center, Qilu Institute of Technology, Shandong, PR China. Electronic address: .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101212. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Glucose*/genetics
Blood Glucose*/metabolism
Gluconeogenesis*
Glycolysis*
Sex Characteristics*
Ion Channels/*deficiency
Liver/*metabolism
Animals ; Female ; Gene Expression Regulation ; Ion Channels/metabolism ; Male ; Mice ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Tytuł :
Follistatin mediates learning and synaptic plasticity via regulation of Asic4 expression in the hippocampus.
Autorzy :
Chen YJ; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Deng SM; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Chen HW; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Tsao CH; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Chen WT; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Cheng SJ; Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Huang HS; Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Tan BC; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Matzuk MM; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Flint J; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095.
Huang GJ; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan; .; Neuroscience Research Center, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.; Healthy Aging Research Center, Chang Gung University, Taoyuan 33302, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan.
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Neuronal Plasticity*
Acid Sensing Ion Channels/*metabolism
Follistatin/*physiology
Hippocampus/*metabolism
Spatial Learning/*physiology
Acid Sensing Ion Channels/genetics ; Animals ; Cognition ; Female ; Long-Term Potentiation ; Male ; Memory ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Synapses/physiology
Czasopismo naukowe
Tytuł :
ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain.
Autorzy :
Lim J; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Tai HH; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Liao WH; Department of Physical Medicine and Rehabilitation, National Taiwan Hospital University, Taipei, Taiwan.
Chu YC; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Hao CM; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Huang YC; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Lee CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Lin SS; Department of Surgery, National Taiwan Hospital University, Taipei, Taiwan.
Hsu S; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Chien YC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Lai DM; Department of Surgery, National Taiwan Hospital University, Taipei, Taiwan.
Chen WS; Department of Physical Medicine and Rehabilitation, National Taiwan Hospital University, Taipei, Taiwan.
Chen CC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Wang JL; Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
Pokaż więcej
Źródło :
ELife [Elife] 2021 Sep 27; Vol. 10. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Mechanotransduction, Cellular*
Neurogenesis*
Ultrasonic Waves*
Acid Sensing Ion Channels/*metabolism
Brain/*metabolism
Neurons/*metabolism
Acid Sensing Ion Channels/genetics ; Animals ; Brain/cytology ; CHO Cells ; Calcium Signaling ; Cricetulus ; Cytoskeleton/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Microtubule-Associated Proteins/metabolism ; Neuropeptides/metabolism ; Phosphorylation ; Pressure ; Time Factors
Czasopismo naukowe
Tytuł :
Gating current noise produced by Brownian models of a voltage sensor.
Autorzy :
Catacuzzeno L; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy. Electronic address: .
Franciolini F; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Bezanilla F; Department of Biochemistry and Molecular Biology, University of Chicago, Gordon Center for Integrative Sciences, Chicago, Illinois.
Eisenberg RS; Department of Physiology and Biophysics, Rush University, Chicago, Illinois; Department of Applied Mathematics, Illinois Institute of Technology, Chicago, Illinois.
Pokaż więcej
Źródło :
Biophysical journal [Biophys J] 2021 Sep 21; Vol. 120 (18), pp. 3983-4001. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ion Channel Gating*
Ion Channels*
Czasopismo naukowe
Tytuł :
The key role of the central cavity in sodium transport through ligand-gated two-pore channels.
Autorzy :
Milenkovic S; Department of Physics, University of Cagliari, 09042 Monserrato, Italy. .
Bodrenko IV
Carpaneto A
Ceccarelli M
Pokaż więcej
Źródło :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2021 Sep 14; Vol. 23 (34), pp. 18461-18474. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Ion Channel Gating*
Ligand-Gated Ion Channels/*physiology
Sodium/*metabolism
COVID-19 ; Ligand-Gated Ion Channels/metabolism ; Ligands ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Tytuł :
Catalytic Asymmetry in Homodimeric H -Pumping Membrane Pyrophosphatase Demonstrated by Non-Hydrolyzable Pyrophosphate Analogs.
Autorzy :
Anashkin VA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119899 Moscow, Russia.
Malinen AM; Department of Life Technologies, University of Turku, FIN-20014 Turku, Finland.
Bogachev AV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119899 Moscow, Russia.
Baykov AA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119899 Moscow, Russia.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 10; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Catalysis*
Diphosphates/*chemistry
Inorganic Pyrophosphatase/*chemistry
Ion Channels/*chemistry
Cell Membrane/enzymology ; Dimerization ; Hydrolysis ; Ion Channels/genetics ; Ion Transport/genetics ; Kinetics ; Potassium/chemistry ; Protons ; Pyrophosphatases
Czasopismo naukowe
Tytuł :
HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD-ligand interactions.
Autorzy :
Zhao C; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.
Hong L; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.
Galpin JD; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA.
Riahi S; Department of Chemistry, University of California, Irvine, Irvine, CA.
Lim VT; Department of Chemistry, University of California, Irvine, Irvine, CA.
Webster PD; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.
Tobias DJ; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.; Department of Chemistry, University of California, Irvine, Irvine, CA.
Ahern CA; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA.
Tombola F; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Sep 06; Vol. 153 (9). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Arginine*
Ion Channels*/metabolism
Binding Sites ; Humans ; Ligands ; Protons
Czasopismo naukowe
Tytuł :
A novel Hv1 inhibitor reveals a new mechanism of inhibition of a voltage-sensing domain.
Autorzy :
Zhao C; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.
Hong L; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.
Riahi S; Department of Chemistry, University of California, Irvine, Irvine, CA.
Lim VT; Department of Chemistry, University of California, Irvine, Irvine, CA.
Tobias DJ; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.; Department of Chemistry, University of California, Irvine, Irvine, CA.
Tombola F; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Sep 06; Vol. 153 (9). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Ion Channel Gating*
Ion Channels*/metabolism
Potassium ; Protons
Czasopismo naukowe
Tytuł :
Piezo1-Pannexin1 complex couples force detection to ATP secretion in cholangiocytes.
Autorzy :
Desplat A; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Penalba V; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Gros E; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Parpaite T; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Coste B; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Delmas P; Aix-Marseille-Université, Centre National de la Recherche Scientifique, Laboratoire de Neurosciences Cognitives, UMR 7291, CS80011, Marseille, France.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Dec 06; Vol. 153 (12). Date of Electronic Publication: 2021 Oct 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Triphosphate*
Connexins*/genetics
Epithelial Cells*/metabolism
Ion Channels*/genetics
Ion Channels*/metabolism
Nerve Tissue Proteins*/genetics
Animals ; Calcium/metabolism ; Cell Membrane/metabolism ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł :
Toward a More General Understanding of Bohr's Complementarity: Insights from Modeling of Ion Channels.
Autorzy :
Kesić S; Department of Neurophysiology, Institute for Biological Research 'Siniša Stanković'-National Institute of the Republic of Serbia, University of Belgrade, Despot Stefan Blvd., 142, 11060, Belgrade, Serbia. .
Pokaż więcej
Źródło :
Acta biotheoretica [Acta Biotheor] 2021 Dec; Vol. 69 (4), pp. 723-744. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Ion Channels*
Czasopismo naukowe
Tytuł :
Analysis of the mechanosensor channel functionality of TACAN.
Autorzy :
Niu Y; Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, United States.
Tao X; Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, United States.; Howard Hughes Medical Institute, New York, United States.
Vaisey G; Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, United States.; Howard Hughes Medical Institute, New York, United States.
Olinares PDB; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University, New York, United States.
Alwaseem H; Proteomics Resource Center, Rockefeller University, New York, United States.
Chait BT; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University, New York, United States.
MacKinnon R; Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, United States.; Howard Hughes Medical Institute, New York, United States.
Pokaż więcej
Źródło :
ELife [Elife] 2021 Aug 10; Vol. 10. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ion Channels/*chemistry
Ion Channels/*metabolism
Lipid Bilayers/*chemistry
Lipid Bilayers/*metabolism
Animals ; Biosensing Techniques ; CHO Cells ; Cricetulus ; Cryoelectron Microscopy ; HEK293 Cells ; Humans ; Ion Channels/genetics ; Mechanotransduction, Cellular/physiology ; Mice ; Vesicular Transport Proteins/chemistry ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase.
Autorzy :
Xue J; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.
Han Y; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.
Baniasadi H; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, United States.
Zeng W; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.
Pei J; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, United States.
Grishin NV; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, United States.
Wang J; Department of pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, United States.
Tu BP; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, United States.
Jiang Y; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United States.
Pokaż więcej
Źródło :
ELife [Elife] 2021 Aug 10; Vol. 10. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Coenzyme A/*metabolism
Fatty Acid Elongases/*chemistry
Fatty Acids/*chemistry
Ion Channels/*chemistry
Ion Channels/*metabolism
Carrier Proteins ; Electrophysiological Phenomena ; Fatty Acids/classification ; Fatty Acids/metabolism ; HEK293 Cells ; Humans ; Ion Channels/genetics ; Lipid Metabolism ; Membrane Proteins ; Membranes ; Protein Binding
Czasopismo naukowe
Tytuł :
Discovery and characterization of H v 1-type proton channels in reef-building corals.
Autorzy :
Rangel-Yescas G; Departmento de Fisiología, Facultad of Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Cervantes C; Departmento de Fisiología, Facultad of Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Cervantes-Rocha MA; Departmento de Fisiología, Facultad of Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Suárez-Delgado E; Departmento de Fisiología, Facultad of Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Banaszak AT; Unidad Académica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Puerto Morelos, Mexico.
Maldonado E; EvoDevo Research Group, Unidad Académica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Puerto Morelos, Mexico.
Ramsey IS; Department of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, United States.
Rosenbaum T; Departmento of Neurociencia Cognitiva, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Islas LD; Departmento de Fisiología, Facultad of Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Pokaż więcej
Źródło :
ELife [Elife] 2021 Aug 06; Vol. 10. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protons*
Anthozoa/*metabolism
Ion Channels/*metabolism
Animals ; Coral Reefs ; Hydrogen-Ion Concentration ; Ion Channels/genetics ; Seawater/chemistry
Czasopismo naukowe
Tytuł :
The Intracellular N-Terminal Domain of the Acid-Sensing Ion Channel 1a Participates in Channel Opening and Membrane Expression.
Autorzy :
Li W; Department of Neurology, Xijing Hospital Air Force Medical University, Xi'an, China (W.L., X.W., D.W.), and The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China (X.M.).
Wang X; Department of Neurology, Xijing Hospital Air Force Medical University, Xi'an, China (W.L., X.W., D.W.), and The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China (X.M.).
Meng X; Department of Neurology, Xijing Hospital Air Force Medical University, Xi'an, China (W.L., X.W., D.W.), and The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China (X.M.).
Wei D; Department of Neurology, Xijing Hospital Air Force Medical University, Xi'an, China (W.L., X.W., D.W.), and The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China (X.M.) .
Pokaż więcej
Źródło :
Molecular pharmacology [Mol Pharmacol] 2021 Aug; Vol. 100 (2), pp. 113-118. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Acid Sensing Ion Channels/*chemistry
Acid Sensing Ion Channels/*metabolism
Cell Membrane/*metabolism
Acid Sensing Ion Channels/genetics ; Amino Acid Motifs ; Animals ; CHO Cells ; Cricetulus ; Protein Domains ; Transfection
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies