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Tytuł:
Influence of Trabeculectomy with Mitomycin C on Longitudinal Changes in the Visual Field in Glaucoma Patients with High Myopia
Autorzy:
Yamagata Y
Suda K
Akagi T
Ikeda HO
Kameda T
Hasegawa T
Miyake M
Tsujikawa A
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Temat:
glaucoma
myopia
trabeculectomy
glaucoma progression
Ophthalmology
RE1-994
Źródło:
Clinical Ophthalmology, Vol Volume 17, Pp 2413-2422 (2023)
Opis pliku:
electronic resource
Relacje:
https://www.dovepress.com/influence-of-trabeculectomy-with-mitomycin-c-on-longitudinal-changes-i-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483
Dostęp URL:
https://doaj.org/article/5fffc6a96e584a779821558aae5b2803  Link otwiera się w nowym oknie
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Changes in the deep vasculature assessed using anterior segment OCT angiography following trabecular meshwork targeted minimally invasive glaucoma surgery.
Autorzy:
Okamoto Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. .; Division of Ophthalmology and Visual Science, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. .
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Miyake M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Numa S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 13; Vol. 12 (1), pp. 17187. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glaucoma*/diagnostic imaging
Glaucoma*/surgery
Glaucoma, Open-Angle*/diagnostic imaging
Glaucoma, Open-Angle*/surgery
Fluorescein Angiography/methods ; Humans ; Intraocular Pressure ; Longitudinal Studies ; Prospective Studies ; Retinal Vessels ; Tomography, Optical Coherence/methods ; Trabecular Meshwork/diagnostic imaging ; Trabecular Meshwork/surgery
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage.
Autorzy:
Kusaka M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. .; Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan. .
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. .
Inoue Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Iwai S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Iida K; Medical Research Support Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 28; Vol. 12 (1), pp. 16156. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
N-Methylaspartate*/metabolism
Retinal Ganglion Cells*/metabolism
Animals ; Endothelin Receptor Antagonists/pharmacology ; Endothelin-1/metabolism ; Mice ; Neuroprotection ; Tunicamycin/pharmacology ; Valosin Containing Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Longitudinal changes in complete avascular area assessed using anterior segmental optical coherence tomography angiography in filtering trabeculectomy bleb.
Autorzy:
Kido A; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Akagi T; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .; Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, 1-757, Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. .
Ikeda HO; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kameda T; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Suda K; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Miyake M; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Numa S; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 03; Vol. 11 (1), pp. 23418. Date of Electronic Publication: 2021 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glaucoma/*surgery
Mitomycin/*administration & dosage
Tomography, Optical Coherence/*methods
Trabeculectomy/*methods
Adult ; Aged ; Computed Tomography Angiography ; Female ; Glaucoma/diagnostic imaging ; Humans ; Intraocular Pressure ; Longitudinal Studies ; Male ; Middle Aged ; Mitomycin/pharmacology ; Prospective Studies ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Prediction of trabecular meshwork-targeted micro-invasive glaucoma surgery outcomes using anterior segment OCT angiography.
Autorzy:
Okamoto Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. .; Division of Ophthalmology and Visual Science, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan. .
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Miyake M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Numa S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kadomoto S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Uji A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Sep 08; Vol. 11 (1), pp. 17850. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glaucoma/*surgery
Trabecular Meshwork/*surgery
Adult ; Aged ; Aged, 80 and over ; Angiography ; Eye/diagnostic imaging ; Female ; Glaucoma/diagnostic imaging ; Humans ; Intraocular Pressure ; Longitudinal Studies ; Male ; Middle Aged ; Prospective Studies ; Tomography, Optical Coherence ; Trabecular Meshwork/diagnostic imaging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats.
Autorzy:
Iwai S; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .
Mera H; Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
Nishitani K; Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Saito M; Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kakizuka A; Laboratory of Functional Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 02; Vol. 11 (1), pp. 15651. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoarthritis*
Animals ; Apoptosis ; Cartilage, Articular/metabolism ; Chondrocytes/metabolism ; Male ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.
Autorzy:
Saito M; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nishitani K; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .
Ikeda HO; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshida S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iwai S; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ji X; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakahata A; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito A; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakamura S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kuriyama S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshitomi H; Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Murata K; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Advanced Medicine of Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Aoyama T; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito H; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Advanced Medicine of Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kuroki H; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kakizuka A; Laboratory of Functional Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan. .
Matsuda S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 29; Vol. 11 (1), pp. 7442. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinical Characteristics, Differential Diagnosis and Genetic Analysis of Concentric Retinitis Pigmentosa.
Autorzy:
Nakahara M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Oishi A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.; Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8504, Japan.
Miyata M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Numa S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Otsuka Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Oishi M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
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Źródło:
Life (Basel, Switzerland) [Life (Basel)] 2021 Mar 22; Vol. 11 (3). Date of Electronic Publication: 2021 Mar 22.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Longitudinal changes in superficial microvasculature in glaucomatous retinal nerve fiber layer defects after disc hemorrhage.
Autorzy:
Okamoto Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. .
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Miyake M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Nakano E; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Uji A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 16; Vol. 10 (1), pp. 22058. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glaucoma*/metabolism
Glaucoma*/pathology
Optic Disk*/metabolism
Optic Disk*/pathology
Retinal Ganglion Cells*/metabolism
Retinal Ganglion Cells*/pathology
Retinal Hemorrhage*/metabolism
Retinal Hemorrhage*/pathology
Retinal Vessels*/metabolism
Retinal Vessels*/pathology
Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Short-Term Effects of Different Types of Anti-Glaucoma Eyedrop on the Sclero-Conjunctival Vasculature Assessed Using Anterior Segment OCTA in Normal Human Eyes: A Pilot Study.
Autorzy:
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Okamoto Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Nakanishi H; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Miyake M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Yamada T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Kadomoto S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Uji A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Dec 11; Vol. 9 (12). Date of Electronic Publication: 2020 Dec 11.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model.
Autorzy:
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan.; Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan. .
Iwai S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan.
Sasaoka N; Laboratory of Functional Biology, Kyoto University Graduate School of Biostudies, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.
Kakizuka A; Laboratory of Functional Biology, Kyoto University Graduate School of Biostudies, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 10; Vol. 10 (1), pp. 21653. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glaucoma/*pathology
Humulus/*chemistry
Plant Extracts/*pharmacology
Retinal Ganglion Cells/*drug effects
Animals ; Disease Models, Animal ; Mice ; Mice, Knockout ; Retinal Ganglion Cells/pathology ; Tomography, Optical Coherence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
EYS is a major gene involved in retinitis pigmentosa in Japan: genetic landscapes revealed by stepwise genetic screening.
Autorzy:
Numa S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Oishi A; Department of Ophthalmology and Visual Sciences, Nagasaki University, Sakamoto 1-7-1, Nagasaki, 852-8102, Japan. .
Higasa K; Department of Genome Analysis, Institute of Biomedical Science, Kansai Medical University, Osaka, Japan.
Oishi M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Kyoto Okamoto Memorial Hospital, Kyoto, Japan.
Miyata M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Otsuka Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 27; Vol. 10 (1), pp. 20770. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Eye Proteins/*genetics
Genetic Testing/*methods
Retinitis Pigmentosa/*diagnosis
Adult ; Aged ; Female ; Humans ; Japan/epidemiology ; Male ; Middle Aged ; Retinitis Pigmentosa/epidemiology ; Retinitis Pigmentosa/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.
Autorzy:
Saito M; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nishitani K; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .
Ikeda HO; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshida S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iwai S; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ji X; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakahata A; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito A; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakamura S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kuriyama S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshitomi H; Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Murata K; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Advanced Medicine of Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Aoyama T; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito H; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Advanced Medicine of Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kuroki H; Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kakizuka A; Laboratory of Functional Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan. .
Matsuda S; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 27; Vol. 10 (1), pp. 20787. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Naphthalenes/*therapeutic use
Osteoarthritis/*drug therapy
Pyridines/*therapeutic use
Sulfonic Acids/*therapeutic use
Valosin Containing Protein/*antagonists & inhibitors
Adenosine Triphosphate/metabolism ; Aged ; Animals ; Apoptosis/drug effects ; Cartilage, Articular/drug effects ; Cartilage, Articular/injuries ; Cartilage, Articular/metabolism ; Cells, Cultured ; Chondrocytes/drug effects ; Chondrocytes/metabolism ; Chondrocytes/pathology ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Disease Progression ; Endoplasmic Reticulum Stress/drug effects ; Female ; Humans ; Male ; Osteoarthritis/etiology ; Osteoarthritis/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Tunicamycin/toxicity ; Wounds and Injuries/complications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Wavelength of light and photophobia in inherited retinal dystrophy.
Autorzy:
Otsuka Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Oishi A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. .; Department of Ophthalmology and Visual Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. .
Miyata M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Oishi M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Numa S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Sep 09; Vol. 10 (1), pp. 14798. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Photophobia/*physiopathology
Retinal Dystrophies/*physiopathology
Electroretinography ; Humans ; Light ; Retinitis Pigmentosa/physiopathology ; Visual Acuity/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oral administration of ferulic acid or ethyl ferulate attenuates retinal damage in sodium iodate-induced retinal degeneration mice.
Autorzy:
Kohno M; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Musashi K; Medical Platform Co. Ltd., Osaka, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Horibe T; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Matsumoto A; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Kawakami K; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2020 May 26; Vol. 10 (1), pp. 8688. Date of Electronic Publication: 2020 May 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Caffeic Acids/*therapeutic use
Coumaric Acids/*therapeutic use
Retinal Degeneration/*prevention & control
Administration, Oral ; Animals ; Caffeic Acids/pharmacology ; Cell Line ; Cell Survival/drug effects ; Coumaric Acids/pharmacology ; Electroretinography ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Humans ; Hydrogen Peroxide/toxicity ; Iodates/toxicity ; Lipopolysaccharides/toxicity ; Mice ; Mice, Inbred C57BL ; Protective Agents/pharmacology ; Protective Agents/therapeutic use ; Retina/diagnostic imaging ; Retina/metabolism ; Retina/pathology ; Retinal Degeneration/chemically induced ; Retinal Degeneration/pathology ; Tomography, Optical Coherence
Czasopismo naukowe
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Tytuł:
Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model.
Autorzy:
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan. .
Gotoh N; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
Iida K; Medical Research Support Center, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
Iwai S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
Nakano N; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
Kakizuka A; Laboratory of Functional Biology, Kyoto University Graduate School of Biostudies & Solution Oriented Research for Science and Technology, Kyoto, 606-8501, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 06; Vol. 10 (1), pp. 4251. Date of Electronic Publication: 2020 Mar 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Susceptibility*
Transcriptome*
Retinal Diseases/*etiology
Retinal Diseases/*metabolism
Retinal Ganglion Cells/*metabolism
Valosin Containing Protein/*genetics
Valosin Containing Protein/*metabolism
Acute Disease ; Animals ; Apoptosis ; Biomarkers ; Computational Biology/methods ; Disease Models, Animal ; Energy Metabolism ; Gene Expression Profiling ; Gene Ontology ; Immunophenotyping ; Metabolic Networks and Pathways ; Mice ; N-Methylaspartate/adverse effects ; Retinal Diseases/pathology
Czasopismo naukowe
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Tytuł:
Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial.
Autorzy:
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Muraoka Y; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hata M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Sumi E; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Ikeda T; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Nakagawa T; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Abe H; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Tada H; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Morita S; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Kakizuka A; Laboratory of Functional Biology, Kyoto University Graduate School of Biostudies & Solution Oriented Research for Science and Technology, Kyoto, Japan.
Yoshimura N; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło:
PloS one [PLoS One] 2020 Feb 13; Vol. 15 (2), pp. e0229068. Date of Electronic Publication: 2020 Feb 13 (Print Publication: 2020).
Typ publikacji:
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroprotective Agents/*therapeutic use
Retinal Artery Occlusion/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Macular Edema/drug therapy ; Male ; Middle Aged ; Retina/drug effects ; Retinal Vein Occlusion/drug therapy ; Visual Acuity/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Baerveldt or Ahmed glaucoma valve implantation with pars plana tube insertion in Japanese eyes with neovascular glaucoma: 1-year outcomes.
Autorzy:
Suda M; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Nakanishi H; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Murakami T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Suzuma K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Morooka S; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan, .
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Źródło:
Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] 2018 Nov 28; Vol. 12, pp. 2439-2449. Date of Electronic Publication: 2018 Nov 28 (Print Publication: 2018).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of Structure-Function Relationships in Longitudinal Changes of Glaucoma using the Spectralis OCT Follow-Up Mode.
Autorzy:
Suda K; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. .
Akagi T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Nakanishi H; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Noma H; Department of Data Science, The Institute of Statistical Mathematics, 10-3 Midori-cho, Tachikawa, Tokyo, 190-8562, Japan.
Ikeda HO; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Kameda T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Hasegawa T; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Tsujikawa A; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
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Źródło:
Scientific reports [Sci Rep] 2018 Nov 21; Vol. 8 (1), pp. 17158. Date of Electronic Publication: 2018 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Eye/*diagnostic imaging
Glaucoma/*pathology
Glaucoma/*physiopathology
Tomography, Optical Coherence/*methods
Adult ; Aged ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 29

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