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Wyszukujesz frazę ""Ikemizu, S"" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł:
Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Autorzy:
Nakamura T; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. .; Priority Organization for Innovation and Excellence, Kumamoto University, Kumamoto, Japan. .
Hashikawa C; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Okabe K; School of Pharmacy, Kumamoto University, Kumamoto, Japan.
Yokote Y; School of Pharmacy, Kumamoto University, Kumamoto, Japan.
Chirifu M; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Toma-Fukai S; Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Japan.
Nakamura N; School of Pharmacy, Kumamoto University, Kumamoto, Japan.
Matsuo M; Priority Organization for Innovation and Excellence, Kumamoto University, Kumamoto, Japan.
Kamikariya M; School of Pharmacy, Kumamoto University, Kumamoto, Japan.
Okamoto Y; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Gohda J; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Akiyama T; Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Semba K; Department of Life Science and Medical Bioscience, Waseda University, Tokyo, Japan.
Ikemizu S; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Otsuka M; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Inoue JI; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.; Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Yamagata Y; Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 20; Vol. 10 (1), pp. 5152. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity, Innate/*immunology
Intracellular Signaling Peptides and Proteins/*metabolism
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/*ultrastructure
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Humans ; Intracellular Signaling Peptides and Proteins/physiology ; Mice ; NF-kappa B/metabolism ; Pathogen-Associated Molecular Pattern Molecules/immunology ; Pathogen-Associated Molecular Pattern Molecules/metabolism ; Phosphorylation ; Protein Kinases/metabolism ; Signal Transduction/physiology ; TNF Receptor-Associated Factor 6/metabolism ; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł:
Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.
Autorzy:
Kojima T; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Tsuchiya K; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences. Tokyo 113-8519, Japan.
Ikemizu S; Division of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University. Kumamoto 862-0973, Japan.
Yoshikawa S; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Yamanishi Y; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Watanabe M; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences. Tokyo 113-8519, Japan.
Karasuyama H; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
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Źródło:
Scientific reports [Sci Rep] 2016 Nov 07; Vol. 6, pp. 36457. Date of Electronic Publication: 2016 Nov 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ligands*
Antigens, CD/*metabolism
Membrane Glycoproteins/*metabolism
Amino Acid Sequence ; Animals ; Antigens, CD/chemistry ; Cell Line, Tumor ; Cell Lineage ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Gastrointestinal Tract/cytology ; Gastrointestinal Tract/metabolism ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Lymphocytes/cytology ; Lymphocytes/metabolism ; Membrane Glycoproteins/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Protein Binding ; Rats ; Rats, Sprague-Dawley ; Sequence Alignment ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł:
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Autorzy:
Schubert D; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine and Faculty of Biology, Freiburg University, Freiburg, Germany.
Bode C; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Kenefeck R; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Hou TZ; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Wing JB; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Kennedy A; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Bulashevska A; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Petersen BS; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Schäffer AA; National Library of Medicine, National Institutes of Health, Bethesda, USA.
Grüning BA; Department of Computer Science, University of Freiburg, Freiburg, Germany.
Unger S; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Frede N; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Baumann U; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Witte T; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Schmidt RE; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Dueckers G; Children's Hospital Krefeld, Germany.
Niehues T; Children's Hospital Krefeld, Germany.
Seneviratne S; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Kanariou M; Department of Immunology and Histocompatibility, 'Aghia Sophia' Children's Hospital, Athens, Greece.
Speckmann C; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Ehl S; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Rensing-Ehl A; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Warnatz K; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Rakhmanov M; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Thimme R; Clinic for Internal Medicine 2, University Medical Center Freiburg, Freiburg, Germany.
Hasselblatt P; Clinic for Internal Medicine 2, University Medical Center Freiburg, Freiburg, Germany.
Emmerich F; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany.
Cathomen T; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany.
Backofen R; Department of Computer Science, University of Freiburg, Freiburg, Germany.
Fisch P; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Seidl M; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
May A; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Schmitt-Graeff A; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Ikemizu S; Division of structural biology, Kumamoto University, Kumamoto, Japan.
Salzer U; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Sakaguchi S; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Walker LSK; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Sansom DM; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Grimbacher B; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
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Źródło:
Nature medicine [Nat Med] 2014 Dec; Vol. 20 (12), pp. 1410-1416. Date of Electronic Publication: 2014 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Agammaglobulinemia/*genetics
Autoimmune Diseases/*genetics
CTLA-4 Antigen/*genetics
T-Lymphocytes, Regulatory/*immunology
Adolescent ; Adult ; Agammaglobulinemia/immunology ; Anemia, Hemolytic, Autoimmune/genetics ; Anemia, Hemolytic, Autoimmune/immunology ; Animals ; Autoimmune Diseases/immunology ; B-Lymphocytes/immunology ; B7-1 Antigen/metabolism ; CTLA-4 Antigen/immunology ; Child ; Codon, Nonsense ; Endocytosis/genetics ; Endocytosis/immunology ; Exons ; Female ; Granuloma/genetics ; Granuloma/immunology ; Heterozygote ; Humans ; Immune System Diseases/genetics ; Lung Diseases, Interstitial/genetics ; Lung Diseases, Interstitial/immunology ; Male ; Mice ; Middle Aged ; Mutation, Missense ; Pedigree ; Polyendocrinopathies, Autoimmune/genetics ; Polyendocrinopathies, Autoimmune/immunology ; Purpura, Thrombocytopenic, Idiopathic/genetics ; Purpura, Thrombocytopenic, Idiopathic/immunology ; Recurrence ; Respiratory Tract Infections/genetics ; Respiratory Tract Infections/immunology ; Syndrome ; Young Adult
SCR Disease Name:
Autoimmune enteropathy
Czasopismo naukowe
Tytuł:
Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans.
Autorzy:
Chirifu M; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.
Hayashi C
Nakamura T
Toma S
Shuto T
Kai H
Yamagata Y
Davis SJ
Ikemizu S
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Źródło:
Nature immunology [Nat Immunol] 2007 Sep; Vol. 8 (9), pp. 1001-7. Date of Electronic Publication: 2007 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Structure, Quaternary*
Interleukin-15/*chemistry
Interleukin-15 Receptor alpha Subunit/*chemistry
Amino Acid Sequence ; Crystallization ; Humans ; Interleukin-15/genetics ; Interleukin-2/chemistry ; Interleukin-2/genetics ; Molecular Sequence Data ; Protein Binding ; Receptors, Interleukin-2/chemistry ; Receptors, Interleukin-2/genetics ; Sequence Homology, Amino Acid ; Structural Homology, Protein
Czasopismo naukowe
Tytuł:
The nature of molecular recognition by T cells.
Autorzy:
Davis SJ; Nuffield Department of Clinical Medicine, Weatherall Institute of Molecular Medicine, The University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK. />Ikemizu S
Evans EJ
Fugger L
Bakker TR
van der Merwe PA
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Źródło:
Nature immunology [Nat Immunol] 2003 Mar; Vol. 4 (3), pp. 217-24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Immunoconjugates*
Lymphocyte Activation/*immunology
Receptors, Antigen, T-Cell/*immunology
T-Lymphocytes/*immunology
Abatacept ; Animals ; Antigens, CD ; Antigens, Differentiation/immunology ; CD2 Antigens/immunology ; CD28 Antigens/immunology ; CD4 Antigens/immunology ; CD8 Antigens/immunology ; CTLA-4 Antigen ; Glycosylation ; Mice ; Protein Binding ; Rats
Czasopismo naukowe
Tytuł:
A functional and structural basis for TCR cross-reactivity in multiple sclerosis.
Autorzy:
Lang HL; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.
Jacobsen H
Ikemizu S
Andersson C
Harlos K
Madsen L
Hjorth P
Sondergaard L
Svejgaard A
Wucherpfennig K
Stuart DI
Bell JI
Jones EY
Fugger L
Pokaż więcej
Źródło:
Nature immunology [Nat Immunol] 2002 Oct; Vol. 3 (10), pp. 940-3. Date of Electronic Publication: 2002 Sep 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HLA-DR Antigens/*immunology
Herpesvirus 4, Human/*immunology
Multiple Sclerosis/*immunology
Myelin Basic Protein/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*immunology
Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Cell Line ; Cross Reactions ; Crystallography, X-Ray ; HLA-DR Antigens/chemistry ; HLA-DRB1 Chains ; HLA-DRB5 Chains ; Humans ; Mice ; Mice, Transgenic ; Models, Molecular ; Myelin Basic Protein/chemistry ; Protein Structure, Tertiary ; Receptors, Antigen, T-Cell, alpha-beta/genetics
Czasopismo naukowe
Tytuł:
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses.
Autorzy:
Stamper CC; Departments of Biological Chemistry and Musculoskeletal Sciences, Wyeth Research, 87 Cambridge Park Drive, Cambridge, Massachusetts 02140, USA.
Zhang Y
Tobin JF
Erbe DV
Ikemizu S
Davis SJ
Stahl ML
Seehra J
Somers WS
Mosyak L
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Źródło:
Nature [Nature] 2001 Mar 29; Vol. 410 (6828), pp. 608-11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoconjugates*
Antigens, Differentiation/*chemistry
B7-1 Antigen/*chemistry
T-Lymphocytes/*immunology
Abatacept ; Animals ; Antigens, CD ; Antigens, Differentiation/genetics ; Antigens, Differentiation/immunology ; B7-1 Antigen/genetics ; B7-1 Antigen/immunology ; CHO Cells ; CTLA-4 Antigen ; Cricetinae ; Cricetulus ; Crystallography, X-Ray ; Humans ; Immunity/physiology ; Macromolecular Substances ; Mice ; Models, Molecular ; Mutation ; Protein Conformation ; Recombinant Proteins/chemistry ; T-Lymphocytes/chemistry
Czasopismo naukowe
Tytuł:
Structural basis of cell-cell adhesion by NCAM.
Autorzy:
Kasper C; Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen O, Denmark.
Rasmussen H
Kastrup JS
Ikemizu S
Jones EY
Berezin V
Bock E
Larsen IK
Pokaż więcej
Źródło:
Nature structural biology [Nat Struct Biol] 2000 May; Vol. 7 (5), pp. 389-93.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Adhesion*
Neural Cell Adhesion Molecules/*chemistry
Neural Cell Adhesion Molecules/*metabolism
Amino Acid Sequence ; Animals ; Binding Sites ; Calcium/metabolism ; Crystallography, X-Ray ; Dimerization ; Heparin/metabolism ; Hydrogen Bonding ; Immunoglobulins/chemistry ; Models, Molecular ; Molecular Sequence Data ; Protein Binding ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Rats ; Sequence Alignment ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
CD2 and the nature of protein interactions mediating cell-cell recognition.
Autorzy:
Davis SJ; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, UK. />Ikemizu S
Wild MK
van der Merwe PA
Pokaż więcej
Źródło:
Immunological reviews [Immunol Rev] 1998 Jun; Vol. 163, pp. 217-36.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Protein Conformation*
CD2 Antigens/*chemistry
Amino Acid Sequence ; Animals ; CD2 Antigens/metabolism ; Humans ; Molecular Sequence Data
Czasopismo naukowe
    Wyświetlanie 1-10 z 10

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