Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Ikemizu S"" wg kryterium: Wszystkie pola


Tytuł :
Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Autorzy :
Nakamura T; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.; Priority Organization for Innovation and Excellence, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Okabe K; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Hirayama S; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Chirifu M; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Ikemizu S; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Morioka H; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.
Nakabeppu Y; Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Yamagata Y; Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, 862-0973 Kumamoto, Japan.; Shokei University and Shokei University Junior College, 2-6-78, Kuhonji, Chuo-ku, Kumamoto, 862-8678 Kumamoto, Japan.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 09; Vol. 49 (12), pp. 7154-7163.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Glycosylases/*chemistry
Adenine ; Adenomatous Polyposis Coli/genetics ; Amino Acid Motifs ; Animals ; DNA/chemistry ; DNA Glycosylases/genetics ; DNA Repair ; DNA Replication ; Guanine/analogs & derivatives ; Humans ; Mice ; Models, Molecular ; Mutation ; Proliferating Cell Nuclear Antigen/chemistry ; Zinc
Czasopismo naukowe
Tytuł :
A functional and structural basis for T cell receptor crossreactivity in multiple sclerosis
Autorzy :
Lang, H.
Jacobsen, H.
Ikemizu, S.
Andersson, C.
Harlos, K.
Madsen, L.
Hjorth, P.
Søndergaard, L.
Svejgaard, A.
Wucherpfennig, K.
Stuart, D.I.
Bell, J.I.
Jones, E.Y.
Fugger, L.
Pokaż więcej
Źródło :
Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Søndergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D I, Bell, J I, Jones, E Y & Fugger, L 2002, ' A functional and structural basis for T cell receptor crossreactivity in multiple sclerosis ', Nature Immunology, vol. 3, pp. 940-943 .
Tytuł :
A molecular and preclinical comparison of the PD-1-targeted T-cell checkpoint inhibitors nivolumab and pembrolizumab.
Autorzy :
Fessas P; School of Clinical Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
Lee H; School of Clinical Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Ikemizu S; Division of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Janowitz T; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, United Kingdom; Department of Oncology, University of Cambridge, Cambridge Biomedical Research Centre and Addenbrooke's Hospital, Cambridge, United Kingdom. Electronic address: .
Pokaż więcej
Źródło :
Seminars in oncology [Semin Oncol] 2017 Apr; Vol. 44 (2), pp. 136-140. Date of Electronic Publication: 2017 Jul 04.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Antibodies, Monoclonal, Humanized/*pharmacology
Antineoplastic Agents/*pharmacology
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
T-Lymphocytes/*immunology
Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal, Humanized/chemistry ; Antineoplastic Agents/chemistry ; Humans ; Lymphocyte Activation/drug effects ; Molecular Structure ; Nivolumab ; Programmed Cell Death 1 Receptor/chemistry
Czasopismo naukowe
Tytuł :
Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity.
Autorzy :
Waz S; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.
Nakamura T; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.; the Priority Organization for Innovation and Excellence, Kumamoto University, Kumamoto 862-0973.
Hirata K; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.
Koga-Ogawa Y; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.
Chirifu M; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.
Arimori T; the Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki 319-1106, and.
Tamada T; the Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki 319-1106, and.
Ikemizu S; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973.
Nakabeppu Y; the Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.
Yamagata Y; From the Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2017 Feb 17; Vol. 292 (7), pp. 2785-2794. Date of Electronic Publication: 2016 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair Enzymes/*metabolism
Phosphoric Monoester Hydrolases/*metabolism
Crystallography, X-Ray ; DNA Repair Enzymes/chemistry ; DNA Repair Enzymes/genetics ; Humans ; Kinetics ; Mutation ; Phosphoric Monoester Hydrolases/chemistry ; Phosphoric Monoester Hydrolases/genetics ; Protein Conformation ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.
Autorzy :
Kojima T; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Tsuchiya K; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences. Tokyo 113-8519, Japan.
Ikemizu S; Division of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University. Kumamoto 862-0973, Japan.
Yoshikawa S; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Yamanishi Y; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Watanabe M; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences. Tokyo 113-8519, Japan.
Karasuyama H; Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2016 Nov 07; Vol. 6, pp. 36457. Date of Electronic Publication: 2016 Nov 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ligands*
Antigens, CD/*metabolism
Membrane Glycoproteins/*metabolism
Amino Acid Sequence ; Animals ; Antigens, CD/chemistry ; Cell Line, Tumor ; Cell Lineage ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Gastrointestinal Tract/cytology ; Gastrointestinal Tract/metabolism ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Lymphocytes/cytology ; Lymphocytes/metabolism ; Membrane Glycoproteins/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Protein Binding ; Rats ; Rats, Sprague-Dawley ; Sequence Alignment ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression.
Autorzy :
Zhang, Dengyang (AUTHOR)
Guo, Yao (AUTHOR)
Zhao, Yuming (AUTHOR)
Yu, Liuting (AUTHOR)
Chang, Zhiguang (AUTHOR)
Pei, Hanzhong (AUTHOR)
Huang, Junbin (AUTHOR)
Chen, Chun (AUTHOR)
Xue, Hongman (AUTHOR)
Xu, Xiaojun (AUTHOR)
Pan, Yihang (AUTHOR)
Li, Ningning (AUTHOR)
Zhu, Chengming (AUTHOR)
Zhao, Zhizhuang Joe (AUTHOR)
Yu, Jian (AUTHOR)
Chen, Yun (AUTHOR)
Pokaż więcej
Źródło :
Microbial Cell Factories. 3/10/2021, Vol. 20 Issue 1, p1-13. 13p.
Czasopismo naukowe
Tytuł :
The genetic variation landscape of African swine fever virus reveals frequent positive selection and adaptive flexibility.
Autorzy :
Bao YJ; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, China.
Qiu J; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, 430062, China.
Luo Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150001, China.
Rodríguez F; IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA), Universitat Autonòma de Barcelona, Bellaterra, 08193, Spain.
Qiu HJ; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150001, China.
Pokaż więcej
Źródło :
Transboundary and emerging diseases [Transbound Emerg Dis] 2021 Mar 09. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Autorzy :
Schubert D; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine and Faculty of Biology, Freiburg University, Freiburg, Germany.
Bode C; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Kenefeck R; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Hou TZ; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Wing JB; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Kennedy A; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Bulashevska A; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Petersen BS; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Schäffer AA; National Library of Medicine, National Institutes of Health, Bethesda, USA.
Grüning BA; Department of Computer Science, University of Freiburg, Freiburg, Germany.
Unger S; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Frede N; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Baumann U; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Witte T; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Schmidt RE; Department of Pediatric Pulmonology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
Dueckers G; Children's Hospital Krefeld, Germany.
Niehues T; Children's Hospital Krefeld, Germany.
Seneviratne S; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Kanariou M; Department of Immunology and Histocompatibility, 'Aghia Sophia' Children's Hospital, Athens, Greece.
Speckmann C; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Ehl S; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Rensing-Ehl A; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Warnatz K; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Rakhmanov M; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Thimme R; Clinic for Internal Medicine 2, University Medical Center Freiburg, Freiburg, Germany.
Hasselblatt P; Clinic for Internal Medicine 2, University Medical Center Freiburg, Freiburg, Germany.
Emmerich F; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany.
Cathomen T; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.; Institute for Cell and Gene Therapy, University Medical Center Freiburg, Freiburg, Germany.
Backofen R; Department of Computer Science, University of Freiburg, Freiburg, Germany.
Fisch P; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Seidl M; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
May A; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Schmitt-Graeff A; Department of Pathology, University Medical Center Freiburg, Freiburg, Germany.
Ikemizu S; Division of structural biology, Kumamoto University, Kumamoto, Japan.
Salzer U; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Sakaguchi S; WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Walker LSK; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Sansom DM; UCL Institute of Immunity and Transplantation, Royal Free Campus, London, UK.
Grimbacher B; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.
Pokaż więcej
Źródło :
Nature medicine [Nat Med] 2014 Dec; Vol. 20 (12), pp. 1410-1416. Date of Electronic Publication: 2014 Oct 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Agammaglobulinemia/*genetics
Autoimmune Diseases/*genetics
CTLA-4 Antigen/*genetics
T-Lymphocytes, Regulatory/*immunology
Adolescent ; Adult ; Agammaglobulinemia/immunology ; Anemia, Hemolytic, Autoimmune/genetics ; Anemia, Hemolytic, Autoimmune/immunology ; Animals ; Autoimmune Diseases/immunology ; B-Lymphocytes/immunology ; B7-1 Antigen/metabolism ; CTLA-4 Antigen/immunology ; Child ; Codon, Nonsense ; Endocytosis/genetics ; Endocytosis/immunology ; Exons ; Female ; Granuloma/genetics ; Granuloma/immunology ; Heterozygote ; Humans ; Immune System Diseases/genetics ; Lung Diseases, Interstitial/genetics ; Lung Diseases, Interstitial/immunology ; Male ; Mice ; Middle Aged ; Mutation, Missense ; Pedigree ; Polyendocrinopathies, Autoimmune/genetics ; Polyendocrinopathies, Autoimmune/immunology ; Purpura, Thrombocytopenic, Idiopathic/genetics ; Purpura, Thrombocytopenic, Idiopathic/immunology ; Recurrence ; Respiratory Tract Infections/genetics ; Respiratory Tract Infections/immunology ; Syndrome ; Young Adult
SCR Disease Name :
Autoimmune enteropathy
Czasopismo naukowe
Tytuł :
Translational relevance of baseline peripheral blood biomarkers to assess the efficacy of anti-programmed cell death 1 use in solid malignancies.
Autorzy :
Varayathu, Hrishi (AUTHOR)
Sarathy, Vinu (AUTHOR)
Thomas, Beulah (AUTHOR)
Mufti, Suhail (AUTHOR)
Sangi, Lalram (AUTHOR)
Thungappa, Satheesh (AUTHOR)
Tripathi, Priyank (AUTHOR)
Naik, Radheshyam (AUTHOR)
Thomas, Beulah Elsa (AUTHOR)
Mufti, Suhail Sayeed (AUTHOR)
Thungappa, Satheesh Chiradoni (AUTHOR)
Pokaż więcej
Źródło :
Journal of Cancer Research & Therapeutics. Jan-Mar2021, Vol. 17 Issue 1, p114-121. 8p.
Czasopismo naukowe
Tytuł :
Ozanimod to Treat Relapsing Forms of Multiple Sclerosis: A Comprehensive Review of Disease, Drug Efficacy and Side Effects.
Autorzy :
Lassiter, Grace
Melancon, Carlie
Rooney, Tyler
Murat, Anne-Marie
Kaye, Jessica S.
Kaye, Adam M.
Kaye, Rachel J.
Cornett, Elyse M.
Kaye, Alan D.
Shah, Rutvij J.
Viswanath, Omar
Urits, Ivan
Pokaż więcej
Źródło :
Neurology International. Dec2020, Vol. 12 Issue 3, p89-108. 19p.
Czasopismo naukowe
Tytuł :
Lactoferrin Glu561 Asp facilitates secondary amyloidosis in the cornea.
Autorzy :
Araki-Sosaki, K.
Ando, Y.
Nakomura, M.
Kitagawa, K.
Ikemizu, S.
Kawaji, T.
Yamashita, T.
Ueda, M.
Hirano, K.
Yamada, M.
Matsumoto, K.
Kinoshita, S.
Tanthara, H.
Pokaż więcej
Temat :
AMYLOID
LACTOFERRIN
AMYLOIDOSIS
OPHTHALMOLOGY
GENETIC polymorphisms
GENETIC mutation
Źródło :
British Journal of Ophthalmology; Jun2005, Vol. 89 Issue 6, p684-688, 5p, 2 Color Photographs, 1 Black and White Photograph, 1 Diagram, 3 Charts
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies