Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia.
Autorzy:
Hupp S; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012, Bern, Switzerland. Grandgirard D; Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3010, Bern, Switzerland. Mitchell TJ; Institute of Microbiology and Infection, College of Medical and Dental Sciences, Biosciences Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. Leib SL; Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3010, Bern, Switzerland. Hathaway LJ; Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3010, Bern, Switzerland. IlievAI; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012, Bern, Switzerland. asparouh.iliev@ana.unibe.ch.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2019 May 18; Vol. 16 (1), pp. 105. Date of Electronic Publication: 2019 May 18.
Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O.
Autorzy:
Maurer J; Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology and Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078, Würzburg, Germany. Hupp S; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012, Bern, Switzerland.; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology and Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078, Würzburg, Germany. Pillich H; Institute of Medical Microbiology, Justus Liebig University Giessen, Schubertstr. 81, 35392, Giessen, Germany.; German Centre for Infection research (DZIF), Partner site Giessen-Marburg-Langen, Campus Giessen, Giessen, Germany. Mitchell TJ; Chair of Microbial Infection and Immunity, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. Chakraborty T; Institute of Medical Microbiology, Justus Liebig University Giessen, Schubertstr. 81, 35392, Giessen, Germany.; German Centre for Infection research (DZIF), Partner site Giessen-Marburg-Langen, Campus Giessen, Giessen, Germany. IlievAI; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012, Bern, Switzerland. asparouh.iliev@ana.unibe.ch.; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology and Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078, Würzburg, Germany. asparouh.iliev@ana.unibe.ch.
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Źródło:
Scientific reports [Sci Rep] 2018 Oct 26; Vol. 8 (1), pp. 15846. Date of Electronic Publication: 2018 Oct 26.
The inflammatory response and neuronal injury in Streptococcus suis meningitis.
Autorzy:
Seele J; Department of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany. jana_.; Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany. jana_. Tauber SC; Department of Neurology, RWTH University Hospital, Aachen, Germany. Bunkowski S; Department of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany. Baums CG; Institute for Bacteriology and Mycology, Center for Infectious Diseases, Faculty of Veterinary Medicine, University Leipzig, Leipzig, Germany. Valentin-Weigand P; Institute for Microbiology, Center for Infection Medicine, University of Veterinary Medicine Hannover, Hannover, Germany. de Buhr N; Department of Physiological Chemistry, Department of Infectious Diseases, University of Veterinary Medicine Hannover, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany. Beineke A; Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany. IlievAI; Institute of Anatomy, University of Bern, Bern, Switzerland. Brück W; Department of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany. Nau R; Department of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany.; Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2018 Jul 03; Vol. 18 (1), pp. 297. Date of Electronic Publication: 2018 Jul 03.
Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.
Autorzy:
Hupp S; Institute of Anatomy, University of Bern, Bern, Switzerland.; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany. Ribes S; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany.; Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany. Seele J; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany.; Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany. Bischoff C; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany. Förtsch C; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany. Maier E; Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany. Benz R; Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany. Mitchell TJ; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Nau R; Department of Neuropathology, University Medical Center Göttingen, Göttingen, Germany.; Department of Geriatrics, Evangelisches Krankenhaus Göttingen-Weende, Göttingen, Germany. IlievAI; Institute of Anatomy, University of Bern, Bern, Switzerland.; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Würzburg, Germany.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2017 Dec; Vol. 174 (23), pp. 4295-4307. Date of Electronic Publication: 2017 Oct 19.
Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes.
Autorzy:
Maurer J; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. jana_.; Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120 Heidelberg, Germany. jana_. Hupp S; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. .; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012 Bern, Switzerland. . Bischoff C; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. carolin_. Foertsch C; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. . Mitchell TJ; Chair of Microbial Infection and Immunity, Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. . Chakraborty T; Institute for Medical Microbiology, University of Giessen, Schubertstr. 81, 35392 Giessen, Germany. . IlievAI; DFG Membrane/Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Biomedical Science, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. asparouh.iliev@ana.unibe.ch.; Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3012 Bern, Switzerland. asparouh.iliev@ana.unibe.ch.
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Źródło:
Toxins [Toxins (Basel)] 2017 Jan 13; Vol. 9 (1). Date of Electronic Publication: 2017 Jan 13.
Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.
Autorzy:
Förtsch C; DFG Membrane, Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology & Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany. />Hupp S Ma J Mitchell TJ Maier E Benz R IlievAI
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Źródło:
Toxins [Toxins (Basel)] 2011 Jan; Vol. 3 (1), pp. 43-62. Date of Electronic Publication: 2011 Jan 07.
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