Autor: "Imamura K." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Proteasome impairment in neural cells derived from HMSN-P patient iPSCs.
Autorzy:: Murakami N; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 770-8503, Japan.
Imamura K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
Izumi Y; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 770-8503, Japan.
Egawa N; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
Tsukita K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
Enami T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
Yamamoto T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
Kawarai T; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 770-8503, Japan.
Kaji R; Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 770-8503, Japan.
Inoue H; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2017 Feb 15; Vol. 10 (1), pp. 7. Date of Electronic Publication: 2017 Feb 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hereditary Sensory and Motor Neuropathy/*metabolism
Hereditary Sensory and Motor Neuropathy/*pathology
Induced Pluripotent Stem Cells/*metabolism
Neurons/*metabolism
Neurons/*pathology
Proteasome Endopeptidase Complex/*metabolism
Aged ; Aged, 80 and over ; Cell Differentiation ; Clone Cells ; Female ; Humans ; Male ; Middle Aged ; Motor Neurons/pathology ; Mutation/genetics ; Phenotype ; Proteins/genetics ; Spinal Cord/pathology

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Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
Autorzy:: Imamura K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Sahara N; Department of Functional Brain Imaging Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Kanaan NM; Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.
Tsukita K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Kondo T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Kutoku Y; Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Ohsawa Y; Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Sunada Y; Department of Neurology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Kawakami K; Division of Molecular and Developmental Biology, National Institute of Genetics and Department of Genetics, SOKENDAI (The Graduate University for Advanced Studies), Mishima, Shizuoka, Japan.
Hotta A; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Yawata S; Department of Biological Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Watanabe D; Department of Biological Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hasegawa M; Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Trojanowski JQ; Center for Neurodegenerative Disease Research, Institute on Aging, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Lee VM; Center for Neurodegenerative Disease Research, Institute on Aging, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Suhara T; Department of Functional Brain Imaging Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Higuchi M; Department of Functional Brain Imaging Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Inoue H; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Oct 10; Vol. 6, pp. 34904. Date of Electronic Publication: 2016 Oct 10.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium/*metabolism
Frontotemporal Lobar Degeneration/*physiopathology
Induced Pluripotent Stem Cells/*drug effects
Induced Pluripotent Stem Cells/*pathology
Neurons/*drug effects
Neurons/*pathology
Cell Survival ; Cells, Cultured ; Humans ; Models, Biological ; Protein Folding ; tau Proteins/genetics ; tau Proteins/metabolism