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Wyszukujesz frazę ""Imidazoles"" wg kryterium: Temat


Starter badań:

Tytuł :
Benzofuranyl-2-imidazoles as imidazoline I 2 receptor ligands for Alzheimer's disease.
Autorzy :
Rodriguez-Arévalo S; Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain.
Bagán A; Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain.
Griñán-Ferré C; Pharmacology Section, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain.
Vasilopoulou F; Pharmacology Section, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain.
Pallàs M; Pharmacology Section, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institut de Neurociències, University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain.
Brocos-Mosquera I; Department of Pharmacology, University of the Basque Country, UPV/EHU, E-48940, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain.
Callado LF; Department of Pharmacology, University of the Basque Country, UPV/EHU, E-48940, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain.
Loza MI; Innopharma Screening Platform, BioFarma Research Group, Centro de Investigación en Medicina Molecular y Enfermedades Crónica (CIMUS), Universidad de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Martínez AL; Innopharma Screening Platform, BioFarma Research Group, Centro de Investigación en Medicina Molecular y Enfermedades Crónica (CIMUS), Universidad de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Brea J; Innopharma Screening Platform, BioFarma Research Group, Centro de Investigación en Medicina Molecular y Enfermedades Crónica (CIMUS), Universidad de Santiago de Compostela, E-15782, Santiago de Compostela, Spain.
Pérez B; Department of Pharmacology, Therapeutic and Toxicology, Autonomous University of Barcelona, E-08193, Cerdanyola, Spain.
Molins E; Institut de Ciència de Materials de Barcelona (CSIC), Campus UAB, E-08193, Cerdanyola, Spain.
De Jonghe S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Daelemans D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Radan M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, 11000, Belgrade, Serbia.
Djikic T; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, 11000, Belgrade, Serbia.
Nikolic K; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, 11000, Belgrade, Serbia.
Hernández-Hernández E; IUNICS University of the Balearic Islands (UIB), Health Research Institute of the Balearic Islands (IdISBa), E-07122, Palma de Mallorca, Spain.
García-Fuster MJ; IUNICS University of the Balearic Islands (UIB), Health Research Institute of the Balearic Islands (IdISBa), E-07122, Palma de Mallorca, Spain.
García-Sevilla JA; IUNICS University of the Balearic Islands (UIB), Health Research Institute of the Balearic Islands (IdISBa), E-07122, Palma de Mallorca, Spain.
Escolano C; Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 15; Vol. 222, pp. 113540. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Benzofurans/*pharmacology
Imidazoles/*pharmacology
Imidazoline Receptors/*antagonists & inhibitors
Alzheimer Disease/metabolism ; Animals ; Apoptosis/drug effects ; Benzofurans/chemical synthesis ; Benzofurans/chemistry ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Humans ; Imidazoles/chemical synthesis ; Imidazoles/chemistry ; Imidazoline Receptors/metabolism ; Ligands ; Male ; Mice ; Molecular Structure ; Oxidative Stress/drug effects ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Computational study of the therapeutic potentials of a new series of imidazole derivatives against SARS-CoV-2.
Autorzy :
Johnson TO; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria. Electronic address: .
Adegboyega AE; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria.
Iwaloye O; Bioinformatics and Molecular Biology Unit, Department of Biochemistry, Federal University of Technology, Akure.
Eseola OA; Department of Chemical Sciences, Redeemer's University, Ede, Nigeria; Friedrich-Schiller-Universität Jena, Institute of Inorganic and Analytical Chemistry, Humboldtstraße 8, 07743, Jena, Germany.
Plass W; Friedrich-Schiller-Universität Jena, Institute of Inorganic and Analytical Chemistry, Humboldtstraße 8, 07743, Jena, Germany.
Afolabi B; Department of Biochemistry, Medicinal Biochemistry, Nanomedicine & Toxicology Laboratory, Landmark University, PMB 1001, Omu-Aran -, 251101, Nigeria.
Rotimi D; Department of Biochemistry, Medicinal Biochemistry, Nanomedicine & Toxicology Laboratory, Landmark University, PMB 1001, Omu-Aran -, 251101, Nigeria.
Ahmed EI; Department of Pharmacology and Therapeutics, College of Medicine, Jouf University, Sakaka, 72346, Saudi Arabia; Department of Pharmacology, Faculty of Medicine, Fayoum University, Fayoum, 63511, Egypt.
Albrakati A; Department of Human Anatomy, College of Medicine, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia. Electronic address: .
Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt.
Adeyemi OS; Department of Biochemistry, Medicinal Biochemistry, Nanomedicine & Toxicology Laboratory, Landmark University, PMB 1001, Omu-Aran -, 251101, Nigeria. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2021 Sep; Vol. 147 (1), pp. 62-71. Date of Electronic Publication: 2021 May 23.
Typ publikacji :
Journal Article
MeSH Terms :
Computational Biology/*methods
Enzyme Inhibitors/*pharmacology
Imidazoles/*pharmacology
Molecular Docking Simulation/*methods
SARS-CoV-2/*drug effects
Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/metabolism ; Humans ; Imidazoles/chemistry ; Imidazoles/metabolism ; Protein Binding/physiology ; Protein Structure, Secondary ; Protein Structure, Tertiary ; SARS-CoV-2/chemistry ; SARS-CoV-2/metabolism
Czasopismo naukowe
Tytuł :
Death associated with brorphine, an emerging novel synthetic opioid.
Autorzy :
Vohra V; Michigan Poison Center, Wayne State University School of Medicine, Detroit, Michigan, USA.
King AM; Michigan Poison Center, Wayne State University School of Medicine, Detroit, Michigan, USA.; Detroit Medical Center, Department of Emergency Medicine, Detroit, Michigan, USA.
Jacobs E; Detroit Medical Center, Department of Emergency Medicine, Detroit, Michigan, USA.
Aaron C; Michigan Poison Center, Wayne State University School of Medicine, Detroit, Michigan, USA.
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Źródło :
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2021 Sep; Vol. 59 (9), pp. 851-852. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Analgesics, Opioid/*toxicity
Drug Overdose/*mortality
Fentanyl/*toxicity
Imidazoles/*toxicity
Opioid-Related Disorders/*mortality
Piperidines/*toxicity
Synthetic Drugs/*toxicity
Cause of Death ; Fatal Outcome ; Female ; Fentanyl/blood ; Fentanyl/urine ; Humans ; Imidazoles/blood ; Imidazoles/urine ; Michigan ; Middle Aged ; Opioid-Related Disorders/epidemiology ; Piperidines/blood ; Piperidines/urine ; Population Surveillance
Raport
Tytuł :
Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inhibitors.
Autorzy :
Al-Wahaibi LH; Department of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11564, Saudi Arabia.
Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Taher ES; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
Abdelazeem AH; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.; Department of Pharmaceutical Sciences, College of Pharmacy, Riyadh Elm University, Riyadh 11681, Saudi Arabia.
Abdelhamid AA; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.; Chemistry Department, Faculty of Science, Albaha University, P.O. Box 1988, Albaha 65731, Saudi Arabia.
Marzouk AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 04; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Computational Biology*
Drug Design*
Carbonic Anhydrase IX/*metabolism
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Imidazoles/*chemical synthesis
Imidazoles/*pharmacology
Sulfonamides/*chemical synthesis
Antineoplastic Agents/pharmacology ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Doxorubicin/pharmacology ; Humans ; Imidazoles/chemistry ; Molecular Docking Simulation ; Structure-Activity Relationship ; Sulfonamides/chemistry ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł :
Efficacy and safety of ponatinib for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: a case series from a single institute.
Autorzy :
Kidoguchi K; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Ureshino H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan. .
Kizuka-Sano H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Yamaguchi K; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Katsuya H; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Kubota Y; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.; Department of Transfusion Medicine, Saga University Hospital, Saga, Japan.
Ando T; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Miura M; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Takahashi N; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Kimura S; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2021 Aug; Vol. 114 (2), pp. 199-204. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Fusion Proteins, bcr-abl/*antagonists & inhibitors
Imidazoles/*therapeutic use
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Pyridazines/*therapeutic use
Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Combined Modality Therapy ; Disease Management ; Female ; Fusion Proteins, bcr-abl/genetics ; Humans ; Imidazoles/administration & dosage ; Imidazoles/adverse effects ; Male ; Middle Aged ; Molecular Targeted Therapy/methods ; Philadelphia Chromosome ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/adverse effects ; Pyridazines/administration & dosage ; Pyridazines/adverse effects ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Development and optimization of a new tioconazole vaginal mucoadhesive film using an experimental design strategy. Physicochemical and biological characterization.
Autorzy :
Calvo NL; Instituto de Química Rosario (IQUIR, CONICET-UNR), Suipacha 570, Rosario, S2002LRK, Argentina; Área Análisis de Medicamentos, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario, S2002LRK, Argentina. Electronic address: .
Tejada G; Área Técnica Farmacéutica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario, S2002LRK, Argentina.
Svetaz LA; Área Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario, S2002LRK, Argentina.
Quiroga AD; Instituto de Fisiología Experimental (IFISE, CONICET-UNR), Suipacha 570, Rosario, S2002LRL, Argentina.
Alvarez VA; Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA, CONICET-UNMdP), Colón 10890, Mar del Plata, 7600, Argentina.
Lamas MC; Instituto de Química Rosario (IQUIR, CONICET-UNR), Suipacha 570, Rosario, S2002LRK, Argentina; Área Técnica Farmacéutica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario, S2002LRK, Argentina.
Leonardi D; Instituto de Química Rosario (IQUIR, CONICET-UNR), Suipacha 570, Rosario, S2002LRK, Argentina; Área Técnica Farmacéutica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario, S2002LRK, Argentina. Electronic address: .
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Oct 25; Vol. 205, pp. 114303. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Imidazoles*
Research Design*
Female ; Humans ; Hypromellose Derivatives ; Polymers
Czasopismo naukowe
Tytuł :
Mix-and-read bioluminescent copper detection platform using a caged coelenterazine analogue.
Autorzy :
Nishihara R; National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan. .; DAILAB, DBT-AIST International Centre for Translational and Environmental Research (DAICENTER), National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.; Japan Science and Technology Agency (JST), PRESTO, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan.
Kurita R; National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan. .; DAILAB, DBT-AIST International Centre for Translational and Environmental Research (DAICENTER), National Institute of Advanced Industrial Science and Technology (AIST), Central 5-41, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.; Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.
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Źródło :
The Analyst [Analyst] 2021 Oct 11; Vol. 146 (20), pp. 6139-6144. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Copper*
Imidazoles*
Humans ; Luciferases ; Pyrazines
Czasopismo naukowe
Tytuł :
Serial evaluation of the pharmacokinetics of ponatinib in patients with CML and Ph + ALL.
Autorzy :
Kawano N; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan. .
Kimura S; Division of Hematology, Department of Internal Medicine, Saga University School of Medicine, Saga, Japan.
Miura M; Division of Pharmacology, Department of Pharmacology, Akita University School of Medicine, Akita, Japan.
Tochigi T; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Nakaike T; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Yamashita K; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Mashiba K; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Kikuchi I; Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Takahashi N; Department of Hematology, Nephrology and Rheumatology, Akita University School of Medicine, Akita, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2021 Oct; Vol. 114 (4), pp. 509-516. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Imidazoles/*pharmacokinetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Protein Kinase Inhibitors/*pharmacokinetics
Pyridazines/*pharmacokinetics
Adult ; Aged ; Combined Modality Therapy ; Drug Monitoring ; Female ; Fusion Proteins, bcr-abl/genetics ; Hematopoietic Stem Cell Transplantation ; Humans ; Imidazoles/administration & dosage ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/etiology ; Leukemia, Myeloid, Chronic-Phase/diagnosis ; Leukemia, Myeloid, Chronic-Phase/drug therapy ; Male ; Middle Aged ; Molecular Targeted Therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/etiology ; Protein Kinase Inhibitors/administration & dosage ; Pyridazines/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Monitoring the behavior of imazalil and its metabolite in grapes, apples, and the processing of fruit wine at enantiomeric level.
Autorzy :
Li R; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Pan X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
An X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Wang K; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Dong F; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Xu J; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Liu X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Wu X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
Zheng Y; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, P. R. China.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Oct; Vol. 101 (13), pp. 5478-5486. Date of Electronic Publication: 2021 Mar 21.
Typ publikacji :
Journal Article
MeSH Terms :
Fungicides, Industrial/*chemistry
Imidazoles/*chemistry
Malus/*chemistry
Vitis/*chemistry
Wine/*analysis
Drug Residues/chemistry ; Drug Residues/metabolism ; Food Contamination/analysis ; Food Handling ; Fruit/chemistry ; Fruit/metabolism ; Fungicides, Industrial/metabolism ; Imidazoles/metabolism ; Malus/metabolism ; Stereoisomerism ; Vitis/metabolism
Czasopismo naukowe
Tytuł :
Biosupramolecular complexes of amphiphilic photosensitizers with human serum albumin and cucurbit[7]uril as carriers for photodynamic therapy.
Autorzy :
Robinson-Duggon J; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile; Departamento de Bioquímica, Facultad de Ciencias Naturales, Exactas y Tecnología, Universidad de Panamá, Panamá 0824, Panamá. Electronic address: .
McTiernan CD; BEaTS Research Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON K1Y4W7, Canada.
Muñoz M; BEaTS Research Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON K1Y4W7, Canada.
Guerra D; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile.
Escobar Álvarez E; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile.
Andrade-Villalobos F; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile; Departamento de Química Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile.
Fierro A; Departamento de Química Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile.
Edwards AM; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile.
Alarcon EI; BEaTS Research Laboratory, Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, ON K1Y4W7, Canada; Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Fuentealba D; Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Santiago, Chile. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2021 Oct; Vol. 223, pp. 112284. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Bridged-Ring Compounds/*chemistry
Imidazoles/*chemistry
Photosensitizing Agents/*chemistry
Serum Albumin, Human/*chemistry
Binding Sites ; Bridged-Ring Compounds/metabolism ; Cell Survival/drug effects ; Fatty Acids/chemistry ; HeLa Cells ; Humans ; Imidazoles/metabolism ; Molecular Docking Simulation ; Photochemotherapy ; Photosensitizing Agents/metabolism ; Photosensitizing Agents/pharmacology ; Protein Binding ; Serum Albumin, Human/metabolism ; Tolonium Chloride/chemistry ; Tolonium Chloride/metabolism
Czasopismo naukowe
Tytuł :
Bone Mineral Density Changes Associated With Pregnancy, Lactation, and Medical Treatments in Premenopausal Women and Effects Later in Life.
Autorzy :
Watts NB; Mercy Health Osteoporosis and Bone Health Services, Cincinnati, Ohio, USA.
Binkley N; Department of Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Owens CD; AbbVie, Inc., North Chicago, Illinois, USA.
Al-Hendy A; Department of Obstetrics and Gynecology, The University of Illinois College of Medicine, Chicago, Illinois, USA.
Puscheck EE; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan, USA.; InVia Fertility, Hoffman Estates, Illinois, USA.
Shebley M; AbbVie, Inc., North Chicago, Illinois, USA.
Schlaff WD; Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Simon JA; IntimMedicine Specialists, Washington, District of Columbia, USA.
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Źródło :
Journal of women's health (2002) [J Womens Health (Larchmt)] 2021 Oct; Vol. 30 (10), pp. 1416-1430. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Bone Density*
Imidazoles*
Female ; Humans ; Lactation ; Medroxyprogesterone Acetate ; Pregnancy ; Sulfones
Czasopismo naukowe
Tytuł :
Nanocomposite of Peroxidase-Like Cucurbit[6]uril with Enzyme-Encapsulated ZIF-8 and Application for Colorimetric Biosensing.
Autorzy :
Mao D; School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, P.R. China.; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Li W; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Zhang F; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Yang S; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Isak AN; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Song Y; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Guo Y; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Cao S; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Zhang R; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Feng C; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Zhu X; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.; Department of Clinical Laboratory Medicine, Shanghai Tenth People's Hospital of Tongji University, Shanghai 200072, P.R. China.
Li G; Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, P.R. China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Aug 25; Vol. 13 (33), pp. 39719-39729. Date of Electronic Publication: 2021 Aug 15.
Typ publikacji :
Journal Article
MeSH Terms :
Bridged-Ring Compounds/*chemistry
Imidazoles/*chemistry
Nanocomposites/*chemistry
Peroxidases/*chemistry
Zeolites/*chemistry
Biosensing Techniques ; Bridged-Ring Compounds/metabolism ; Catalysis ; Colorimetry ; Fluorescent Dyes/chemistry ; Glucose Oxidase/chemistry ; Glucose Oxidase/metabolism ; Hydrogen Peroxide/chemistry ; Imidazoles/metabolism ; Molecular Docking Simulation ; Oxidation-Reduction ; Peroxidases/metabolism ; Printing, Three-Dimensional
Czasopismo naukowe
Tytuł :
Effect of pharmacodynamical interaction between nutlin-3a and aspirin in the activation of p53.
Autorzy :
Awan MS; Department of Electrical Engineering, National University of Sciences and Technology, Islamabad, Pakistan. Electronic address: .
Aslam M; Department of Electrical Engineering, National University of Sciences and Technology, Islamabad, Pakistan.
Liaquat M; Department of Electrical Engineering, National University of Sciences and Technology, Islamabad, Pakistan. Electronic address: .
Bhatti AI; CASPR, Department of Electronic Engineering, Capital University of Science and Technology, Islamabad, Pakistan.
Liaquat A; Department of Biochemistry, Shifa College of Medicine, Shifa Tamer-e-Millat University, Islamabad, Pakistan.
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Źródło :
Journal of theoretical biology [J Theor Biol] 2021 Aug 07; Vol. 522, pp. 110696. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Aspirin*/pharmacology
Imidazoles*/pharmacology
Piperazines*/pharmacology
Tumor Suppressor Protein p53*
Apoptosis ; Cell Line, Tumor ; Humans ; Proto-Oncogene Proteins c-mdm2/metabolism
Czasopismo naukowe
Tytuł :
Necrostatin-1 reduces cardiac and mitochondrial dysfunction in prediabetic rats.
Autorzy :
Apaijai N; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jinawong K; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Singhanat K; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jaiwongkam T; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.
Kerdphoo S; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.
Chattipakorn SC; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.; Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Chattipakorn N; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
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Źródło :
The Journal of endocrinology [J Endocrinol] 2021 Aug 05; Vol. 251 (1), pp. 27-39. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Imidazoles/*pharmacology
Indoles/*pharmacology
Mitochondria, Heart/*drug effects
Prediabetic State/*chemically induced
Prediabetic State/*complications
Ventricular Dysfunction, Left/*drug therapy
Ventricular Dysfunction, Left/*etiology
Animals ; Diet, High-Fat/adverse effects ; Imidazoles/therapeutic use ; Indoles/therapeutic use ; Insulin Resistance ; Male ; Metformin/pharmacology ; Obesity/etiology ; Random Allocation ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Effect of the novel dual orexin receptor antagonist daridorexant on night-time respiratory function and sleep in patients with moderate chronic obstructive pulmonary disease.
Autorzy :
Boof ML; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
Brunke M; Klinische Forschung Hannover-Mitte GmbH, Hannover, Germany.
Esselmann A; Zentrum für Medizinische Studien GmbH, Warendorf, Germany.
Heymer P; Klinische Forschung Dresden GmbH, Dresden, Germany.
Kestermann O; framol-med GmbH Lungenpraxis Rheine, Rheine, Germany.
Lederer K; Advanced Sleep Research, Berlin, Germany.
Fietze I; Advanced Sleep Research, Berlin, Germany.
Ufer M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
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Źródło :
Journal of sleep research [J Sleep Res] 2021 Aug; Vol. 30 (4), pp. e13248. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Imidazoles/*therapeutic use
Orexin Receptor Antagonists/*therapeutic use
Pulmonary Disease, Chronic Obstructive/*drug therapy
Pulmonary Disease, Chronic Obstructive/*physiopathology
Pyrrolidines/*therapeutic use
Respiration/*drug effects
Sleep/*drug effects
Adolescent ; Adult ; Aged ; Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Imidazoles/pharmacology ; Male ; Middle Aged ; Orexin Receptor Antagonists/administration & dosage ; Orexin Receptor Antagonists/pharmacology ; Pulmonary Disease, Chronic Obstructive/complications ; Pyrrolidines/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł :
Randomised clinical trial: comparison of tegoprazan and placebo in non-erosive reflux disease.
Autorzy :
Kim SH; Seoul, South Korea.
Cho KB; Daegu, South Korea.
Chun HJ; Seoul, South Korea.
Lee SW; Ansan, South Korea.
Kwon JG; Daegu, South Korea.
Lee DH; Seongnam, South Korea.
Kim SG; Seoul, South Korea.
Jung HY; Seoul, South Korea.
Kim JW; Seoul, South Korea.
Lee JS; Seoul, South Korea.
Park H; Seoul, South Korea.
Choi SC; Iksan, South Korea.
Jee SR; Busan, South Korea.
Kim HS; Kwangju, South Korea.
Ko KH; Seongnam, South Korea.
Park SJ; Busan, South Korea.
Lee YC; Seoul, South Korea.
Park SH; Seoul, South Korea.
Kim AR; Seoul, South Korea.
Kim EJ; Seoul, South Korea.
Park HW; Seoul, South Korea.
Kim BT; Seoul, South Korea.
Song GS; Seoul, South Korea.
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Źródło :
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 Aug; Vol. 54 (4), pp. 402-411. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastroesophageal Reflux*/drug therapy
Imidazoles*
Benzene Derivatives ; Double-Blind Method ; Heartburn/drug therapy ; Humans ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma.
Autorzy :
Zhang L; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Yang Z; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Sang H; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Jiang Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhou M; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Huang C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Huang C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Wu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhang T; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, PR China.
Zhang X; Department of Neurobiology, Guangdong Province Key Laboratory of Psychiatric Disorders, School of Basic Medical Sciences, Southern Medical University, Guangzhou, PR China.
Wan S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhang J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1541-1552.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Brain Neoplasms/*drug therapy
Glioblastoma/*drug therapy
Imidazoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Quinolones/*pharmacology
src-Family Kinases/*antagonists & inhibitors
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Imidazoles/chemical synthesis ; Imidazoles/chemistry ; Models, Molecular ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Quinolones/chemical synthesis ; Quinolones/chemistry ; Structure-Activity Relationship ; src-Family Kinases/metabolism
Czasopismo naukowe
Tytuł :
Repurposing of FDA-approved drugs against active site and potential allosteric drug-binding sites of COVID-19 main protease.
Autorzy :
Yuce M; Department of Chemical Engineering, Istanbul Technical University, Istanbul, Turkey.
Cicek E; Computational Science and Engineering Division, Informatics Institute, Istanbul Technical University, Istanbul, Turkey.
Inan T; Department of Chemical Engineering, Istanbul Technical University, Istanbul, Turkey.
Dag AB; Department of Molecular Biology and Genetics, Istanbul Technical University, Istanbul, Turkey.
Kurkcuoglu O; Department of Chemical Engineering, Istanbul Technical University, Istanbul, Turkey.
Sungur FA; Computational Science and Engineering Division, Informatics Institute, Istanbul Technical University, Istanbul, Turkey.
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Źródło :
Proteins [Proteins] 2021 Nov; Vol. 89 (11), pp. 1425-1441. Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*metabolism
Benzofurans/*chemistry
Coronavirus 3C Proteases/*metabolism
Drug Repositioning/*methods
Imidazoles/*chemistry
Allosteric Site ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Benzofurans/metabolism ; Benzofurans/pharmacology ; Binding Sites ; Bromocriptine/chemistry ; Bromocriptine/metabolism ; Bromocriptine/pharmacology ; Coronavirus 3C Proteases/antagonists & inhibitors ; Coronavirus 3C Proteases/chemistry ; Diosmin/chemistry ; Diosmin/metabolism ; Hydrazines/chemistry ; Hydrazines/metabolism ; Hydrazines/pharmacology ; Imidazoles/metabolism ; Imidazoles/pharmacology ; Ivermectin/chemistry ; Ivermectin/metabolism ; Ivermectin/pharmacology ; Ligands ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Triazoles/chemistry ; Triazoles/metabolism ; Triazoles/pharmacology ; United States ; United States Food and Drug Administration
Czasopismo naukowe
Tytuł :
Synthesis, Antibacterial and Antifungal Activity of New 3-Aryl-5 H -pyrrolo[1,2- a ]imidazole and 5 H -Imidazo[1,2- a ]azepine Quaternary Salts.
Autorzy :
Demchenko S; Institute of Pharmacology and Toxicology, Antona Tsedika 14, 03057 Kyiv, Ukraine.
Lesyk R; Department of Public Health, Dietetics and Lifestyle Disorders, Faculty of Medicine, University of Information Technology and Management in Rzeszow, 35-225 Rzeszow, Poland.
Yadlovskyi O; Institute of Pharmacology and Toxicology, Antona Tsedika 14, 03057 Kyiv, Ukraine.
Zuegg J; The Community for Open Antimicrobial Drug Discovery (CO-ADD), Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Australia.
Elliott AG; The Community for Open Antimicrobial Drug Discovery (CO-ADD), Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Australia.
Drapak I; Department of General, Inorganic, Physical and Colloidal Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.
Fedchenkova Y; Department of Chemistry and Pharmacy, Nizhyn Mykola Gogol State University, 16600 Nizhyn, Ukraine.
Suvorova Z; Institute of Pharmacology and Toxicology, Antona Tsedika 14, 03057 Kyiv, Ukraine.
Demchenko A; Institute of Pharmacology and Toxicology, Antona Tsedika 14, 03057 Kyiv, Ukraine.; Department of Chemistry and Pharmacy, Nizhyn Mykola Gogol State University, 16600 Nizhyn, Ukraine.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 13; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Anti-Bacterial Agents/*pharmacology
Antifungal Agents/*chemistry
Antifungal Agents/*pharmacology
Imidazoles/*chemistry
Imidazoles/*pharmacology
Anti-Bacterial Agents/chemical synthesis ; Antifungal Agents/chemical synthesis ; Bacteria/drug effects ; Bacterial Infections/drug therapy ; Fungi/drug effects ; HEK293 Cells ; Humans ; Imidazoles/chemical synthesis ; Microbial Sensitivity Tests ; Mycoses/drug therapy ; Salts/chemical synthesis ; Salts/chemistry ; Salts/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Structure-Activity Relationships of the Imidazolium Compounds as Antibacterials of Staphylococcus aureus and Pseudomonas aeruginosa .
Autorzy :
Pałkowski Ł; Department of Pharmaceutical Technology, Faculty of Pharmacy, Nicolaus Copernicus University, Jurasza 2, 85-094 Bydgoszcz, Poland.
Karolak M; Department of Pharmaceutical Technology, Faculty of Pharmacy, Nicolaus Copernicus University, Jurasza 2, 85-094 Bydgoszcz, Poland.
Błaszczyński J; Institute of Computing Science, Poznań University of Technology, Piotrowo 2, 60-965 Poznań, Poland.
Krysiński J; Department of Pharmaceutical Technology, Faculty of Pharmacy, Nicolaus Copernicus University, Jurasza 2, 85-094 Bydgoszcz, Poland.
Słowiński R; Institute of Computing Science, Poznań University of Technology, Piotrowo 2, 60-965 Poznań, Poland.; Systems Research Institute, Polish Academy of Sciences, Newelska 6, 01-447 Warsaw, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 27; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/pharmacology
Imidazoles*/chemistry
Imidazoles*/pharmacology
Pseudomonas aeruginosa/*growth & development
Staphylococcus aureus/*growth & development
Structure-Activity Relationship
Czasopismo naukowe

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