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Tytuł :
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin.
Autorzy :
Czub MP; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Boulton AM; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Rastelli EJ; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Tasker NR; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Maskrey TS; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Blanco IK; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
McQueeney KE; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Bushweller JH; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Minor W; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Wipf P; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Sharlow ER; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.).
Lazo JS; Departments of Molecular Physiology and Biological Physics (M.P.C., A.M.B., J.H.B., W.M.) and Pharmacology (K.E.M., E.R.S., J.S.L.) and Center for Structural Genomics of Infectious Diseases (CSGID) (M.P.C., W.M.), University of Virginia, Charlottesville, Virginia; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania (E.J.R., N.R.T., T.S.M., P.W.); and KeViRx, Inc., Charlottesville, Virginia (I.K.B., E.R.S., J.S.L.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Dec; Vol. 98 (6), pp. 648-657. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Imines/*pharmacology
Neoplasm Proteins/*antagonists & inhibitors
Protein Tyrosine Phosphatases/*antagonists & inhibitors
Pyridines/*pharmacology
Serum Albumin, Human/*metabolism
Binding Sites ; Calorimetry ; Cell Line, Tumor ; Cell Survival/drug effects ; Crystallography, X-Ray ; Enzyme Assays ; Half-Life ; Humans ; Imines/chemistry ; Imines/therapeutic use ; Neoplasm Proteins/metabolism ; Neoplasms/drug therapy ; Neoplasms/pathology ; Protein Tyrosine Phosphatases/metabolism ; Pyridines/chemistry ; Pyridines/therapeutic use ; Serum Albumin, Human/ultrastructure
Czasopismo naukowe
Tytuł :
Occurrence of domoic acid and cyclic imines in marine biota from Lebanon-Eastern Mediterranean Sea.
Autorzy :
Hassoun AER; National Council for Scientific Research, National Center for Marine Sciences, P.O. Box, 534, Batroun, Lebanon. Electronic address: .
Ujević I; Laboratory of Plankton and Shellfish Toxicity, Institute of Oceanography and Fisheries, Šetalište Ivana Meštrovića 63, 21000 Split, Croatia.
Mahfouz C; National Council for Scientific Research, National Center for Marine Sciences, P.O. Box, 534, Batroun, Lebanon.
Fakhri M; National Council for Scientific Research, National Center for Marine Sciences, P.O. Box, 534, Batroun, Lebanon.
Roje-Busatto R; Laboratory of Plankton and Shellfish Toxicity, Institute of Oceanography and Fisheries, Šetalište Ivana Meštrovića 63, 21000 Split, Croatia.
Jemaa S; National Council for Scientific Research, National Center for Marine Sciences, P.O. Box, 534, Batroun, Lebanon.
Nazlić N; Laboratory of Plankton and Shellfish Toxicity, Institute of Oceanography and Fisheries, Šetalište Ivana Meštrovića 63, 21000 Split, Croatia.
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Feb 10; Vol. 755 (Pt 1), pp. 142542. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Biota*
Imines*/analysis
Animals ; Humans ; Kainic Acid/analogs & derivatives ; Lebanon ; Mediterranean Sea
Czasopismo naukowe
Tytuł :
Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice.
Autorzy :
Shibagaki F; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan.
Ishimaru Y; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan. .
Sumino A; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan.; Laboratory of Food Chemistry, Yokohama University of Pharmacy, 601, Matano-cho, Totsuka-ku, Yokohama, Kanagawa, 245-0066, Japan.
Yamamuro A; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan.
Yoshioka Y; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan.
Maeda S; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka, 573-0101, Japan. .
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Źródło :
Neurochemical research [Neurochem Res] 2020 Apr; Vol. 45 (4), pp. 752-759. Date of Electronic Publication: 2020 Jan 01.
Typ publikacji :
Journal Article
MeSH Terms :
Apelin Receptors/*agonists
Imines/*pharmacology
Mesylates/*pharmacology
N-Methylaspartate/*toxicity
Retinal Diseases/*prevention & control
Retinal Neurons/*drug effects
Administration, Oral ; Animals ; Imines/administration & dosage ; Injections, Intraperitoneal ; Intravitreal Injections ; Male ; Mesylates/administration & dosage ; Mice, Inbred C57BL ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Retinal Diseases/metabolism ; Retinal Neurons/metabolism
Czasopismo naukowe
Tytuł :
Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography.
Autorzy :
Platella C; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Pirota V; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
Musumeci D; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Rizzi F; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
Iachettini S; Oncogenomic and Epigenetic Unit, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.
Zizza P; Oncogenomic and Epigenetic Unit, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.
Biroccio A; Oncogenomic and Epigenetic Unit, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.
Freccero M; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
Montesarchio D; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Doria F; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 13; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
G-Quadruplexes/*drug effects
Imines/*chemistry
Naphthalenes/*chemistry
Antineoplastic Agents/pharmacology ; Cell Proliferation/drug effects ; DNA Damage ; HeLa Cells ; Humans ; Imines/pharmacology ; Ligands ; Naphthalenes/pharmacology ; Telomere/drug effects
Czasopismo naukowe
Tytuł :
Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Autorzy :
Nakamura R; Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Saitama, Japan.
Hikita M; Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization, Tsukuba, Japan.
Ogawa S; Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Saitama, Japan.
Takahashi Y; Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Saitama, Japan.
Fujishiro T; Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Saitama, Japan.
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Źródło :
The FEBS journal [FEBS J] 2020 Mar; Vol. 287 (6), pp. 1138-1154. Date of Electronic Publication: 2019 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbon-Sulfur Lyases/*metabolism
Imines/*metabolism
Pyridoxal Phosphate/*metabolism
Bacillus subtilis/enzymology ; Biocatalysis ; Carbon-Sulfur Lyases/chemistry ; Crystallography, X-Ray ; Helicobacter pylori/enzymology ; Imines/chemistry ; Models, Molecular ; Pyridoxal Phosphate/chemistry
Czasopismo naukowe
Tytuł :
Imines and lactones derived from friedelanes and their cytotoxic activity.
Autorzy :
Aguilar MG; Departamento de Química, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.
Sousa GF; Departamento de Química, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.
Evangelista FCG; Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.
Sabino AP; Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.
Vieira Filho SA; Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil.
Duarte LP; Departamento de Química, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.
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Źródło :
Natural product research [Nat Prod Res] 2020 Mar; Vol. 34 (6), pp. 810-815. Date of Electronic Publication: 2018 Nov 02.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Celastraceae/*chemistry
Cytotoxins/*isolation & purification
Imines/*chemistry
Lactones/*chemistry
Triterpenes/*chemistry
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/isolation & purification ; Cell Line, Tumor ; Cytotoxins/chemical synthesis ; Cytotoxins/pharmacology ; Humans ; Imines/chemical synthesis ; Lactones/chemical synthesis ; Plant Leaves/chemistry ; Structure-Activity Relationship ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Heterobinuclear copper(II)‑platinum(II) complexes with oxindolimine ligands: Interactions with DNA, and inhibition of kinase and alkaline phosphatase proteins.
Autorzy :
Aranda EE; Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
da Luz JS; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
Oliveira CC; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
Divina Petersen PA; Departamento de Física dos Materiais e Mecânica, Instituto de Física, Universidade de São Paulo, 05508-090 São Paulo, SP, Brazil.
Petrilli HM; Departamento de Física dos Materiais e Mecânica, Instituto de Física, Universidade de São Paulo, 05508-090 São Paulo, SP, Brazil.
da Costa Ferreira AM; Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil. Electronic address: .
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Źródło :
Journal of inorganic biochemistry [J Inorg Biochem] 2020 Feb; Vol. 203, pp. 110863. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alkaline Phosphatase/*antagonists & inhibitors
Coordination Complexes/*pharmacology
DNA/*metabolism
Imines/*pharmacology
Oxindoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Animals ; Cell Line, Tumor ; Coordination Complexes/metabolism ; Copper/chemistry ; Cyclin-Dependent Kinases/antagonists & inhibitors ; DNA Cleavage/drug effects ; Humans ; Imines/metabolism ; Ligands ; Mice ; Molecular Docking Simulation ; Oxindoles/metabolism ; Platinum/chemistry ; Protein Kinase Inhibitors/metabolism
Czasopismo naukowe
Tytuł :
Synthesis, Characterization and Antimicrobial Activities of Mixed Ligand Complexes of Fe (II), Co(II), Ni(II) and Cu (II) Ions Derived from Imine of Benzidine and o-phenylenediammine.
Autorzy :
Mihsen, Hayder Hamied
Abass, Suhad Kareem
Abed-Alhasan, Maysaa Taqe
Hassan, Zainab M.
Abbas, Ali Kareem
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Alternatywny tytuł :
و ((Fe (II) تحضير وتذخيص والفعاليات المضادة للميكروبات لمعقدات مختلطة الليكندات للأيهنات المذتقة من إيمين البنزيدين و اورثه فنلين ثنائي الامين (Cu (II) و ( Ni (II) وCo (II)).
Źródło :
Iraqi Journal of Science. 2020, Vol. 61 Issue 11, p2762-2775. 14p.
Czasopismo naukowe
Tytuł :
Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies.
Autorzy :
Mamedova G; Laboratory of Faine Organic Synthesis, Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, 1029 Baku, Azerbaijan.
Mahmudova A; Laboratory of Faine Organic Synthesis, Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, 1029 Baku, Azerbaijan.
Mamedov S; Laboratory of Faine Organic Synthesis, Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, 1029 Baku, Azerbaijan.
Erden Y; Department of Molecular Biology and Genetics, Faculty of Science, Bartin University, 74100 Bartin, Turkey.
Taslimi P; Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Turkey. Electronic address: .
Tüzün B; Department of Chemistry, Faculty of Science, Cumhuriyet University, 58140 Sivas, Turkey.
Tas R; Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Turkey.
Farzaliyev V; Laboratory of Faine Organic Synthesis, Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, 1029 Baku, Azerbaijan.
Sujayev A; Laboratory of Faine Organic Synthesis, Institute of Chemistry of Additives, Azerbaijan National Academy of Sciences, 1029 Baku, Azerbaijan.
Alwasel SH; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Gulçin İ; Department of Chemistry, Faculty of Sciences, Ataturk University, 25240 Erzurum, Turkey.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2019 Dec; Vol. 93, pp. 103313. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Docking Simulation*
Antineoplastic Agents/*chemical synthesis
Cholinergic Antagonists/*chemical synthesis
Hypoglycemic Agents/*chemical synthesis
Imines/*chemistry
Acetylcholinesterase/chemistry ; Acetylcholinesterase/metabolism ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/pharmacology ; Binding Sites ; Butyrylcholinesterase/chemistry ; Butyrylcholinesterase/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cholinergic Antagonists/metabolism ; Cholinergic Antagonists/pharmacology ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/metabolism ; Cholinesterase Inhibitors/pharmacology ; Humans ; Hypoglycemic Agents/metabolism ; Hypoglycemic Agents/pharmacology ; Imines/metabolism ; Imines/pharmacology ; Kinetics ; Protein Structure, Tertiary ; Pyrazines/chemistry ; Pyridazines/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis and Antioxidant Activity of Carane and Pinane Based Sulfenimines and Sulfinimines.
Autorzy :
Sudarikov DV; Institute of Chemistry of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 48, Pervomayskaya St., Syktyvkar, 167000, Russia.
Krymskaya YV; Institute of Chemistry of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 48, Pervomayskaya St., Syktyvkar, 167000, Russia.
Shevchenko OG; Institute of Biology of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 28, Kommunisticheskaya St., Syktyvkar, 167982, Russia.
Slepukhin PA; Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22, S. Kovalevskaya St., Ekaterinburg, 620137, Russia.
Rubtsova SA; Institute of Chemistry of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 48, Pervomayskaya St., Syktyvkar, 167000, Russia.
Kutchin AV; Institute of Chemistry of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 48, Pervomayskaya St., Syktyvkar, 167000, Russia.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2019 Nov; Vol. 16 (11), pp. e1900413. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*pharmacology
Bicyclic Monoterpenes/*pharmacology
Imines/*pharmacology
Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Bicyclic Monoterpenes/chemical synthesis ; Bicyclic Monoterpenes/chemistry ; Density Functional Theory ; Dose-Response Relationship, Drug ; Erythrocytes/drug effects ; Humans ; Imines/chemical synthesis ; Imines/chemistry ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Enantioselective extraction of unprotected amino acids coupled with racemization.
Autorzy :
Huang H; College of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Jin Y; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Shirbhate ME; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Kang D; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Choi M; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Chen Q; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Kim Y; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Kim SJ; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
Byun IS; Aminologics Co., R&D Center, Cheongju-si, Chungcheongbuk-do, 28158, Korea.
Wang M; College of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Bouffard J; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea. .
Kim SK; Department of Chemistry, Sungkyunkwan University, Suwon, 16419, Korea. .
Kim KM; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 05; Vol. 12 (1), pp. 125. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemistry Techniques, Synthetic*
Amino Acids/*chemistry
Imines/*chemistry
Ketones/*chemistry
Liquid-Liquid Extraction/*methods
Catalysis ; Copper/chemistry ; Kinetics ; Solvents/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Cooperative TiO 2 photocatalysis with TEMPO and N-hydroxysuccinimide for blue light-driven selective aerobic oxidation of amines.
Autorzy :
Lyu S; Sauvage Center for Molecular Sciences, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Hao H; Sauvage Center for Molecular Sciences, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Li X; Sauvage Center for Molecular Sciences, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Lang X; Sauvage Center for Molecular Sciences, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 Jan; Vol. 262, pp. 127873. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Succinimides/*chemistry
Titanium/*chemistry
Adsorption ; Amines ; Catalysis ; Cyclic N-Oxides ; Imines ; Light ; Oxidation-Reduction ; Semiconductors ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
Synthesis and Penicillin-binding Protein Inhibitory Assessment of Dipeptidic 4-Phenyl-β-lactams from α-Amino Acid-derived Imines.
Autorzy :
Decuyper L; SynBioC Research Group, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.
Jukič M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia.
Sosič I; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia.
Amoroso AM; Centre for Protein Engineering, Faculty of Sciences, University of Liège, Quartier Agora, Allée du 6 Août 13, Bât B6a, 4000, Liège Sart-Tilman, Belgium.
Verlaine O; Centre for Protein Engineering, Faculty of Sciences, University of Liège, Quartier Agora, Allée du 6 Août 13, Bât B6a, 4000, Liège Sart-Tilman, Belgium.
Joris B; Centre for Protein Engineering, Faculty of Sciences, University of Liège, Quartier Agora, Allée du 6 Août 13, Bât B6a, 4000, Liège Sart-Tilman, Belgium.
Gobec S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia.
D'hooghe M; SynBioC Research Group, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.
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Źródło :
Chemistry, an Asian journal [Chem Asian J] 2020 Jan 02; Vol. 15 (1), pp. 51-55. Date of Electronic Publication: 2019 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*pharmacology
Anti-Bacterial Agents/*pharmacology
Dipeptides/*pharmacology
Imines/*pharmacology
Lactams/*pharmacology
Penicillin-Binding Proteins/*antagonists & inhibitors
Amino Acids/chemistry ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Dipeptides/chemical synthesis ; Dipeptides/chemistry ; Imines/chemistry ; Lactams/chemical synthesis ; Lactams/chemistry ; Molecular Structure ; Penicillin-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity.
Autorzy :
D'Andrea F; Department of Pharmacy, University of Pisa, Pisa, Italy.
Sartini S; Department of Pharmacy, University of Pisa, Pisa, Italy.
Piano I; Department of Pharmacy, University of Pisa, Pisa, Italy.
Franceschi M; Department of Pharmacy, University of Pisa, Pisa, Italy.
Quattrini L; Department of Pharmacy, University of Pisa, Pisa, Italy.
Guazzelli L; Department of Pharmacy, University of Pisa, Pisa, Italy.
Ciccone L; Department of Pharmacy, University of Pisa, Pisa, Italy.
Orlandini E; Department of Earth Sciences, University of Pisa, Pisa, Italy.; Research Center 'E. Piaggio', University of Pisa, Pisa, Italy.
Gargini C; Department of Pharmacy, University of Pisa, Pisa, Italy.
La Motta C; Department of Pharmacy, University of Pisa, Pisa, Italy.
Nencetti S; Department of Pharmacy, University of Pisa, Pisa, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1194-1205.
Typ publikacji :
Journal Article
MeSH Terms :
Aldehyde Reductase/*antagonists & inhibitors
Antioxidants/*pharmacology
Enzyme Inhibitors/*pharmacology
Imines/*chemistry
Sugars/*chemistry
Enzyme Inhibitors/chemistry ; Molecular Structure
Czasopismo naukowe
Tytuł :
Three point-mutations in cytochrome b confer resistance to trifloxystrobin in Magnaporthe oryzae.
Autorzy :
Miao J; State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
Zhao G; State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
Wang B; Department of Plant Pathology, , China Agricultural University, Beijing, China.; State Key Laboratory of Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals R&D Co., Ltd, Shenyang, China.
Du Y; Institute of Plant Protection, Fujian Academy of Agricultural Science, Fuzhou, China.
Li Z; Institute for the Control of Agrochemicals of Shaanxi Province, Xi'an, China.
Gao X; State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
Zhang C; Department of Plant Pathology, , China Agricultural University, Beijing, China.
Liu X; State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
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Źródło :
Pest management science [Pest Manag Sci] 2020 Dec; Vol. 76 (12), pp. 4258-4267. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Magnaporthe*/genetics
Oryza*
Acetates ; Ascomycota ; China ; Cytochromes b/genetics ; Imines ; Plant Diseases ; Point Mutation ; Strobilurins
SCR Organism :
Pyricularia oryzae
Czasopismo naukowe
Tytuł :
Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines.
Autorzy :
Liu D; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China.
Li B; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China.
Chen J; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China.
Gridnev ID; Department of Chemistry, Graduate School of Science, Tohoku University, Aramaki 3-6, Aoba-ku, Sendai, 980-8578, Japan.
Yan D; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China.
Zhang W; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 23; Vol. 11 (1), pp. 5935. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycine/*chemical synthesis
Imidoesters/*chemistry
Nickel/*chemistry
Amino Acids/chemical synthesis ; Amino Acids/chemistry ; Catalysis ; Glycine/chemistry ; Hydrogenation ; Imines/chemistry ; Molecular Structure ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Isatidis Folium alleviates acetaminophen-induced liver injury in mice by enhancing the endogenous antioxidant system.
Autorzy :
Ding CH; Department of Pharmacy, Affiliated Hospital of Weifang Medical University, Weifang, China.
Zhu H; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.; Department of Pharmaceutical Analysis and Metabolomics, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2020 Nov; Vol. 35 (11), pp. 1251-1259. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Acetaminophen/*toxicity
Antioxidants/*metabolism
Plant Extracts/*pharmacology
Acetaminophen/metabolism ; Animals ; Benzoquinones ; Chemical and Drug Induced Liver Injury/pathology ; Chemical and Drug Induced Liver Injury, Chronic/metabolism ; Chemical and Drug Induced Liver Injury, Chronic/pathology ; Cytochrome P-450 CYP1A2 ; Glutathione/metabolism ; Imines ; Liver/drug effects ; Male ; Mice ; Plant Leaves
Czasopismo naukowe
Tytuł :
A Kinetic Investigation of Metal-Dipeptide Complex with Ninhydrin in the Absence and Presence of CTAB Micelles.
Autorzy :
Zaidi NH; Department of Chemistry, School of Pure Science, College of Engineering Science and Technology, Fiji National University.
Akram M; Department of Chemistry, Aligarh Muslim University.
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Źródło :
Journal of oleo science [J Oleo Sci] 2020 Nov 01; Vol. 69 (11), pp. 1427-1436. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cetrimonium/*chemistry
Dipeptides/*chemistry
Imines/*chemistry
Metals/*chemistry
Ninhydrin/*chemistry
Surface-Active Agents/*chemistry
Anions/chemistry ; Benzoates/chemistry ; Catalysis ; Hydrogen-Ion Concentration ; Micelles ; Organic Chemistry Phenomena ; Salicylates/chemistry ; Spectrophotometry ; Temperature ; Viscosity ; Water/chemistry
Czasopismo naukowe
Tytuł :
Nanochannels of Covalent Organic Frameworks for Chiral Selective Transmembrane Transport of Amino Acids.
Autorzy :
Yuan C; School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites , Shanghai Jiao Tong University , Shanghai 200240 , China.
Wu X; School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites , Shanghai Jiao Tong University , Shanghai 200240 , China.
Gao R; School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.
Han X; School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites , Shanghai Jiao Tong University , Shanghai 200240 , China.
Liu Y; School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites , Shanghai Jiao Tong University , Shanghai 200240 , China.
Long Y; School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.
Cui Y; School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites , Shanghai Jiao Tong University , Shanghai 200240 , China.
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Źródło :
Journal of the American Chemical Society [J Am Chem Soc] 2019 Dec 26; Vol. 141 (51), pp. 20187-20197. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanotechnology*
Aldehydes/*metabolism
Amino Acids/*metabolism
Diamines/*metabolism
Imines/*metabolism
Aldehydes/chemistry ; Amino Acids/chemistry ; Biological Transport ; Diamines/chemistry ; Imines/chemistry ; Molecular Structure ; Particle Size ; Porosity ; Surface Properties
Czasopismo naukowe
Tytuł :
Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents.
Autorzy :
Wei B; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, PR China.
Zhou J; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, PR China.
Xu JJ; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, PR China.
Cui J; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, PR China.
Ping FF; Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, 214023, PR China.
Ling JJ; Wuxi Children's Hospital, Wuxi, 214023, PR China.
Chen YJ; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, PR China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Dec 15; Vol. 184, pp. 111779. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Antioxidants/*pharmacology
Cardiotonic Agents/*pharmacology
Coumarins/*pharmacology
Imines/*pharmacology
NF-E2-Related Factor 2/*antagonists & inhibitors
Sulfonic Acids/*pharmacology
Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Cardiotonic Agents/chemical synthesis ; Cardiotonic Agents/chemistry ; Cells, Cultured ; Coumarins/chemical synthesis ; Coumarins/chemistry ; Dose-Response Relationship, Drug ; Humans ; Imines/chemistry ; Molecular Structure ; NF-E2-Related Factor 2/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Structure-Activity Relationship ; Sulfonic Acids/chemistry
Czasopismo naukowe

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