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Wyszukujesz frazę ""Immune Evasion"" wg kryterium: Temat


Tytuł :
lncRNA SNHG14 promotes oncogenesis and immune evasion in diffuse large-B-cell lymphoma by sequestering miR-152-3p.
Autorzy :
Tian Y; Department of Hematology, Hainan Cancer Hospital, Haikou, China.
Li L; Department of Hematology, Hainan Cancer Hospital, Haikou, China.
Lin G; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Wang Y; Department of Hematology, Hainan Cancer Hospital, Haikou, China.
Wang L; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Zhao Q; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Hu Y; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Yong H; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Wan Y; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
Zhang Y; Department of Hematology, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, China.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2021 Jul; Vol. 62 (7), pp. 1574-1584. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immune Evasion*
Lymphoma, Large B-Cell, Diffuse*/genetics
MicroRNAs*/genetics
RNA, Long Noncoding*/genetics
Carcinogenesis ; Humans
Czasopismo naukowe
Tytuł :
Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.
Autorzy :
Hsu JC; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Laurent-Rolle M; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520.
Pawlak JB; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520.
Wilen CB; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT 06520.; Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520.
Cresswell P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520; .; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jun 15; Vol. 118 (24).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immune Evasion*
Immunity, Innate*
COVID-19/*immunology
Exoribonucleases/*immunology
Protein Biosynthesis/*immunology
SARS-CoV-2/*immunology
Viral Nonstructural Proteins/*immunology
Animals ; Chlorocebus aethiops ; Humans ; Vero Cells
Czasopismo naukowe
Tytuł :
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
Autorzy :
Zhang Y; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Chen Y; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Li Y; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Huang F; Department of Respiratory Diseases, Guangzhou Women and Children Hospital, 510010, Guangzhou, Guangdong, China.
Luo B; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Yuan Y; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Xia B; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Ma X; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Yang T; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Yu F; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Liu J; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Liu B; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Song Z; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Chen J; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Yan S; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Wu L; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Pan T; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Zhang X; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Li R; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Huang W; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 510000, Guangzhou, Guangdong, China.
He X; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China.
Xiao F; Department of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University, 519000, Zhuhai, Guangdong, China.
Zhang J; Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 510000, Guangzhou, Guangdong, China; .
Zhang H; Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Zhongshan School of Medicine, Sun Yat-sen University, 510080, Guangzhou, Guangdong, China; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jun 08; Vol. 118 (23).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen Presentation*
Immune Evasion*
COVID-19/*immunology
Down-Regulation/*immunology
Histocompatibility Antigens Class I/*immunology
SARS-CoV-2/*immunology
Viral Proteins/*immunology
Animals ; Autophagy/genetics ; Autophagy/immunology ; COVID-19/genetics ; Chlorocebus aethiops ; HEK293 Cells ; Histocompatibility Antigens Class I/genetics ; Humans ; Lysosomes/genetics ; Lysosomes/immunology ; Lysosomes/virology ; Mice ; Mice, Transgenic ; SARS-CoV-2/genetics ; Vero Cells ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Autorzy :
Wang R; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Beijing 100084, China.
Zhang Q; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China.
Ge J; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Collaborative Innovation Center for Biotherapy, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Ren W; Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing 100084, China; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100084, China.
Zhang R; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China.
Lan J; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Collaborative Innovation Center for Biotherapy, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Ju B; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen 518112, Guangdong Province, China; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Su B; Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Yu F; Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, No. 8, Jing Shun Dong Jie, Chaoyang, 100015 District Beijing, China.
Chen P; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China.
Liao H; Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Feng Y; Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Li X; Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Shi X; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China.
Zhang Z; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen 518112, Guangdong Province, China; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Zhang F; Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, No. 8, Jing Shun Dong Jie, Chaoyang, 100015 District Beijing, China.
Ding Q; Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing 100084, China; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100084, China.
Zhang T; Beijing Youan Hospital, Capital Medical University, Beijing 100069, China. Electronic address: .
Wang X; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Collaborative Innovation Center for Biotherapy, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: .
Zhang L; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Beijing Advanced Innovation Center for Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, China. Electronic address: .
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Źródło :
Immunity [Immunity] 2021 Jul 13; Vol. 54 (7), pp. 1611-1621.e5. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immune Evasion*/genetics
Angiotensin-Converting Enzyme 2/*metabolism
Antibodies, Neutralizing/*immunology
SARS-CoV-2/*immunology
Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Antibodies, Neutralizing/chemistry ; Antigenic Variation/genetics ; COVID-19/immunology ; COVID-19/virology ; Host Specificity ; Humans ; Mice ; Mink ; Mutation ; Protein Binding ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/metabolism ; Virus Internalization
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma.
Autorzy :
Sun YF; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Wu L; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences (UCAS), Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Liu SP; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Jiang MM; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.; School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.
Hu B; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Zhou KQ; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Guo W; Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Xu Y; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Zhong Y; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Zhou XR; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences (UCAS), Shenzhen, China.
Zhang ZF; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Liu G; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.
Liu S; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences (UCAS), Shenzhen, China.
Shi YH; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Ji Y; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Du M; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Li NN; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Li GB; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Zhao ZK; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.
Huang XY; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.
Xu LQ; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Yu QC; BGI-Shenzhen, Shenzhen, Beishan Industrial Zone, Shenzhen, China.; Shenzhen Key Laboratory of Single-cell Omics, BGI-Shenzhen, Shenzhen, China.
Peng DH; Dunwill Med-Tech, Shanghai, China.
Qiu SJ; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Sun HC; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.
Dean M; Laboratory of Translational Genomics, Division of Cancer Epidemiology & Genetics, National Cancer Institute Gaithersburg, Rockville, MD, USA.
Wang XD; Zhongshan Hospital Institute of Clinical Science, Shanghai Institute of Clinical Bioinformatics, Fudan University Center for Clinical Bioinformatics, Shanghai, China.
Chung WY; Department of Hepatobiliary and Pancreatic Surgery, University Hospitals of Leicester NHS Trust, Leicester, UK.
Dennison AR; Department of Hepatobiliary and Pancreatic Surgery, University Hospitals of Leicester NHS Trust, Leicester, UK.
Zhou J; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China.; Zhong-Hua Precision Medical Center, Zhongshan Hospital, Fudan University-BGI, Shanghai, People's Republic of China.
Hou Y; Zhong-Hua Precision Medical Center, Zhongshan Hospital, Fudan University-BGI, Shanghai, People's Republic of China. .
Fan J; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China. .; Zhong-Hua Precision Medical Center, Zhongshan Hospital, Fudan University-BGI, Shanghai, People's Republic of China. .
Yang XR; Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, People's Republic of China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 02; Vol. 12 (1), pp. 4091. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Heterogeneity*
Immune Evasion*
Carcinoma, Hepatocellular/*genetics
Carcinoma, Hepatocellular/*immunology
Liver Neoplasms/*genetics
Liver Neoplasms/*immunology
Neoplastic Cells, Circulating/*immunology
Aged ; Animals ; Biomarkers, Tumor/metabolism ; Cell Cycle ; Cell Line, Tumor ; Chemokine CCL5/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Neoplasm Metastasis ; Neoplastic Cells, Circulating/metabolism ; Prognosis ; RNA-Seq ; Transcriptome ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
A comparative review of pathogenesis and host innate immunity evasion strategies among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV).
Autorzy :
Noor R; Department of Life Sciences (DLS), School of Environment and Life Sciences (SELS), Independent University, Bangladesh (IUB), Plot 16, Block B, Aftabuddin Ahmed Road, Bashundhara, Dhaka, 1229, Bangladesh. .
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Źródło :
Archives of microbiology [Arch Microbiol] 2021 Jul; Vol. 203 (5), pp. 1943-1951. Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Immune Evasion*
Betacoronavirus/*pathogenicity
Coronavirus Infections/*immunology
Coronavirus Infections/*virology
Betacoronavirus/classification ; Betacoronavirus/physiology ; Coronavirus Infections/epidemiology ; Cytokines/immunology ; Disease Progression ; Humans ; Immunity, Innate ; Species Specificity ; Virus Internalization
Czasopismo naukowe
Tytuł :
Symptomatic reinfection of SARS-CoV-2 with spike protein variant N440K associated with immune escape.
Autorzy :
Rani PR; Virus Research and Diagnosis Laboratory and Department of Microbiology, Kurnool Medical College, Kurnool, Andhra Pradesh, India.
Imran M; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Lakshmi JV; Department of Microbiology, Kurnool Medical College, Kurnool, Andhra Pradesh, India.
Jolly B; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Jain A; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Surekha A; Department of Microbiology, Kurnool Medical College, Kurnool, Andhra Pradesh, India.
Senthivel V; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Chandrasekhar P; Department of Cardiology, Kurnool Medical College, Kurnool, Andhra Pradesh, India.
Divakar MK; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Srinivasulu D; Department of General Medicine, Kurnool medical college, Kurnool, Andhra Pradesh, India.
Bhoyar RC; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.
Vanaja PR; Department of Biochemistry, Kurnool medical college, Kurnool, Andhra Pradesh, India.
Scaria V; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Sivasubbu S; CSIR- Institute of Genomics and Integrative Biology (CSIR-IGIB), Mathura Road, Delhi, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Jul; Vol. 93 (7), pp. 4163-4165. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Immune Evasion/*immunology
Reinfection/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Genome, Viral/genetics ; Humans ; Immune Evasion/genetics ; Male ; Middle Aged ; Reinfection/virology ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism :
SARS-CoV-2 variants
Raport
Tytuł :
SARS-CoV-2 variants, spike mutations and immune escape.
Autorzy :
Harvey WT; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
Carabelli AM; Department of Medicine, University of Cambridge, Cambridge, UK.
Jackson B; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
Gupta RK; Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK.
Thomson EC; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.; Wellcome Sanger Institute, Hinxton, UK.
Harrison EM; Department of Medicine, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Hinxton, UK.
Ludden C; Department of Medicine, University of Cambridge, Cambridge, UK.
Reeve R; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Rambaut A; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
Peacock SJ; Department of Medicine, University of Cambridge, Cambridge, UK.
Robertson DL; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK. .
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Corporate Authors :
COVID-19 Genomics UK (COG-UK) Consortium
Źródło :
Nature reviews. Microbiology [Nat Rev Microbiol] 2021 Jul; Vol. 19 (7), pp. 409-424. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune Evasion*/genetics
COVID-19/*virology
SARS-CoV-2/*genetics
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*classification
Amino Acids/chemistry ; Amino Acids/genetics ; Antigenic Variation/genetics ; Antigenic Variation/physiology ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19/transmission ; COVID-19 Vaccines/immunology ; COVID-19 Vaccines/standards ; Epitopes/chemistry ; Epitopes/genetics ; Epitopes/immunology ; Humans ; Mutation ; Protein Conformation ; SARS-CoV-2/classification ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology
Czasopismo naukowe
Tytuł :
From Recoding to Peptides for MHC Class I Immune Display: Enriching Viral Expression, Virus Vulnerability and Virus Evasion.
Autorzy :
Atkins JF; Schools of Biochemistry and Microbiology, University College Cork, T12 XF62 Cork, Ireland.
O'Connor KM; Schools of Biochemistry and Microbiology, University College Cork, T12 XF62 Cork, Ireland.
Bhatt PR; Schools of Biochemistry and Microbiology, University College Cork, T12 XF62 Cork, Ireland.; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Loughran G; Schools of Biochemistry and Microbiology, University College Cork, T12 XF62 Cork, Ireland.
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Źródło :
Viruses [Viruses] 2021 Jun 27; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune Evasion*
DNA Viruses/*genetics
DNA Viruses/*immunology
Histocompatibility Antigens Class I/*immunology
RNA Viruses/*genetics
Antiviral Agents/pharmacology ; Codon, Terminator ; DNA Viruses/drug effects ; Frameshifting, Ribosomal ; Histocompatibility Antigens Class I/genetics ; Nucleic Acid Conformation ; Peptides/immunology ; Protein Biosynthesis ; RNA Viruses/drug effects ; RNA Viruses/immunology
Czasopismo naukowe
Tytuł :
Immune Evasion of SARS-CoV-2 Emerging Variants: What Have We Learnt So Far?
Autorzy :
Lazarevic I; Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Pravica V; Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Miljanovic D; Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Cupic M; Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
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Źródło :
Viruses [Viruses] 2021 Jun 22; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immune Evasion*
Antibodies, Viral/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
Antibodies, Neutralizing/immunology ; Humans ; Mutation ; Neutralization Tests ; SARS-CoV-2/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.
Autorzy :
Cele S; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Gazy I; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada, Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel.
Jackson L; Africa Health Research Institute, Durban, South Africa.
Hwa SH; Africa Health Research Institute, Durban, South Africa.; Division of Infection and Immunity, University College London, London, UK.
Tegally H; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Lustig G; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Giandhari J; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Pillay S; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Wilkinson E; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Naidoo Y; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Karim F; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Ganga Y; Africa Health Research Institute, Durban, South Africa.
Khan K; Africa Health Research Institute, Durban, South Africa.
Bernstein M; Africa Health Research Institute, Durban, South Africa.
Balazs AB; Ragon Institute of MGH, Harvard and MIT, Cambridge, MA, USA.
Gosnell BI; Department of Infectious Diseases, Nelson R. Mandela School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.
Hanekom W; Africa Health Research Institute, Durban, South Africa.; Division of Infection and Immunity, University College London, London, UK.
Moosa MS; Department of Infectious Diseases, Nelson R. Mandela School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.
Lessells RJ; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
de Oliveira T; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. .; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa. .; Department of Global Health, University of Washington, Seattle, WA, USA. .
Sigal A; Africa Health Research Institute, Durban, South Africa. .; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. .; Max Planck Institute for Infection Biology, Berlin, Germany. .
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Corporate Authors :
Network for Genomic Surveillance in South Africa
COMMIT-KZN Team
Źródło :
Nature [Nature] 2021 May; Vol. 593 (7857), pp. 142-146. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
COVID-19/*immunology
COVID-19/*therapy
COVID-19/*virology
Immune Evasion/*immunology
SARS-CoV-2/*immunology
Animals ; Antibodies, Neutralizing/biosynthesis ; Antibodies, Viral/biosynthesis ; COVID-19/epidemiology ; Cell Line ; Chlorocebus aethiops ; Humans ; Immune Evasion/genetics ; Immunization, Passive ; Neutralization Tests ; SARS-CoV-2/genetics ; South Africa/epidemiology ; Time Factors ; Vero Cells
SCR Protocol :
COVID-19 serotherapy
Czasopismo naukowe
Tytuł :
Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.
Autorzy :
Truong TT; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Ryutov A; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Pandey U; Department of Pathology, Westchester Medical Center/New York Medical College, Valhalla, NY, United States.
Yee R; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Goldberg L; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Bhojwani D; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Aguayo-Hiraldo P; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Cancer and Blood Disorder Institute, Transplant and Cellular Therapy Section, Children's Hospital Los Angeles, CA, United States.
Pinsky BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Pekosz A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Shen L; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Boyd SD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Sean N. Parker Center for Allergy and Asthma Research, Stanford, CA, United States.
Wirz OF; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Röltgen K; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Bootwalla M; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Maglinte DT; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Ostrow D; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Ruble D; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Han JH; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Biegel JA; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Li M; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Huang C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Sahoo MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Pannaraj PS; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Division of Infectious Diseases, Children's Hospital Los Angeles, Los Angeles, CA, United States.
O'Gorman M; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Judkins AR; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Gai X; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Dien Bard J; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2021 May; Vol. 67, pp. 103355. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Immune Evasion*
Mutation*
COVID-19/*immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*virology
SARS-CoV-2/*genetics
COVID-19/virology ; Child, Preschool ; Evolution, Molecular ; Female ; Genome, Viral ; High-Throughput Nucleotide Sequencing ; Humans ; Immunity, Humoral ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/immunology ; SARS-CoV-2/classification ; SARS-CoV-2/immunology ; Sequence Analysis, RNA ; Whole Genome Sequencing ; Young Adult
Czasopismo naukowe
Tytuł :
Innate immune sensing of coronavirus and viral evasion strategies.
Autorzy :
Kasuga Y; Department of Immunology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan.
Zhu B; Department of Immunology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan.
Jang KJ; Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju, 27478, Republic of Korea. .
Yoo JS; Department of Immunology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan. .
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Źródło :
Experimental & molecular medicine [Exp Mol Med] 2021 May; Vol. 53 (5), pp. 723-736. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune Evasion*
Immunity, Innate*
Coronaviridae/*immunology
Coronavirus Infections/*immunology
Animals ; COVID-19/immunology ; Humans ; Interferons/immunology ; SARS-CoV-2/immunology
Czasopismo naukowe
Tytuł :
SARS-CoV-2 escaped natural immunity, raising questions about vaccines and therapies.
Autorzy :
Andreano E; Monoclonal Antibody Discovery Lab, , Fondazione Toscana Life Sciences, Siena, Italy.
Rappuoli R; Monoclonal Antibody Discovery Lab, , Fondazione Toscana Life Sciences, Siena, Italy. .; Faculty of Medicine, Imperial College London, London, UK. .
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Źródło :
Nature medicine [Nat Med] 2021 May; Vol. 27 (5), pp. 759-761.
Typ publikacji :
Journal Article
MeSH Terms :
Immune Evasion*
COVID-19/*prevention & control
Immunity, Innate/*immunology
SARS-CoV-2/*immunology
Viral Vaccines/*immunology
Humans
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Structure and function of the porcine TAP protein and its inhibition by the viral immune evasion protein ICP47.
Autorzy :
Chai HH; Animal Genome & Bioinformatics Division, National Institute of Animal Science, RDA, Wanju, Republic of Korea; College of Pharmacy, Chonnam National University, Kwangju, Republic of Korea. Electronic address: .
Kim TH; Animal Genome & Bioinformatics Division, National Institute of Animal Science, RDA, Wanju, Republic of Korea.
Kim YR; College of Pharmacy, Chonnam National University, Kwangju, Republic of Korea.
Lim D; Animal Genome & Bioinformatics Division, National Institute of Animal Science, RDA, Wanju, Republic of Korea. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 May 01; Vol. 178, pp. 514-526. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article
MeSH Terms :
Immune Evasion*
ATP-Binding Cassette Transporters/*antagonists & inhibitors
ATP-Binding Cassette Transporters/*chemistry
Immediate-Early Proteins/*chemistry
Simplexvirus/*chemistry
ATP-Binding Cassette Transporters/immunology ; Animals ; Humans ; Immediate-Early Proteins/immunology ; Simplexvirus/immunology ; Structure-Activity Relationship ; Swine
Czasopismo naukowe
Tytuł :
Type I and III interferon responses in SARS-CoV-2 infection.
Autorzy :
Kim YM; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. .; Center for Epidemic Preparedness, KAIST, Daejeon, 34141, Republic of Korea. .
Shin EC; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. .; Center for Epidemic Preparedness, KAIST, Daejeon, 34141, Republic of Korea. .
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Źródło :
Experimental & molecular medicine [Exp Mol Med] 2021 May; Vol. 53 (5), pp. 750-760. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune Evasion*
Immunity, Innate*
COVID-19/*immunology
Interferon Type I/*immunology
Interferons/*immunology
SARS-CoV-2/*immunology
Animals ; COVID-19/genetics ; Gene Expression Regulation ; Humans ; Inflammation/genetics ; Inflammation/immunology ; Interferon Type I/genetics ; Interferons/genetics
Czasopismo naukowe
Tytuł :
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.
Autorzy :
Wang P; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Nair MS; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Liu L; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Iketani S; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.
Luo Y; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Guo Y; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Wang M; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Yu J; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Zhang B; Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.
Kwong PD; Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.; Department of Biochemistry, Columbia University, New York, NY, USA.
Graham BS; Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.
Mascola JR; Vaccine Research Center, National Institutes of Health, Bethesda, MD, USA.
Chang JY; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Yin MT; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Sobieszczyk M; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Kyratsous CA; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Shapiro L; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Department of Biochemistry, Columbia University, New York, NY, USA.; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Sheng Z; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Huang Y; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. .
Ho DD; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. .; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. .; Division of Infectious Diseases, Department of Internal Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. .
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Źródło :
Nature [Nature] 2021 May; Vol. 593 (7857), pp. 130-135. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
COVID-19/*immunology
COVID-19/*therapy
COVID-19 Vaccines/*immunology
Immune Evasion/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adult ; Aged ; Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/therapeutic use ; COVID-19/drug therapy ; COVID-19/prevention & control ; COVID-19/virology ; Chlorocebus aethiops ; Drug Resistance, Viral/immunology ; HEK293 Cells ; Humans ; Immune Evasion/genetics ; Immunization, Passive ; Middle Aged ; Models, Molecular ; Mutation ; Neutralization Tests ; Protein Domains/immunology ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Vaccines, Synthetic/immunology ; Vero Cells
SCR Protocol :
COVID-19 serotherapy
Czasopismo naukowe
Tytuł :
Glimpses into evolutionary trajectories of SARS-CoV-2: emerging variants and potential immune evasion routes.
Autorzy :
Anastassopoulou C; Department of Microbiology, Medical School, National & Kapodistrian University of Athens, Athens, Greece.
Manoussopoulos Y; Department of Microbiology, Medical School, National & Kapodistrian University of Athens, Athens, Greece.; Laboratory of Virology, Plant Protection Division of Patras, ELGO-Demeter, Patras, Greece.
Lampropoulou V; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery & Translational Research, Biomedical Research Foundation of The Academy of Athens, Athens, Greece.
Tsakris A; Department of Microbiology, Medical School, National & Kapodistrian University of Athens, Athens, Greece.
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Źródło :
Future microbiology [Future Microbiol] 2021 May; Vol. 16, pp. 455-459. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Editorial
MeSH Terms :
Evolution, Molecular*
Immune Evasion*
SARS-CoV-2/*genetics
COVID-19/immunology ; COVID-19/virology ; Genome, Viral ; Humans
Opinia redakcyjna
Tytuł :
Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex.
Autorzy :
Dhillon A; Sir William Dunn School of Pathology, Oxford, United Kingdom.
Deme JC; Sir William Dunn School of Pathology, Oxford, United Kingdom.; Central Oxford Structural Molecular Imaging Centre, Oxford, United Kingdom.
Furlong E; Sir William Dunn School of Pathology, Oxford, United Kingdom.
Roem D; Sanquin Research, Department of Immunopathology, and Landsteiner Laboratory, Amsterdam University Medical Centre, Amsterdam Infection and Immunity Institute, Amsterdam, the Netherlands.
Jongerius I; Sanquin Research, Department of Immunopathology, and Landsteiner Laboratory, Amsterdam University Medical Centre, Amsterdam Infection and Immunity Institute, Amsterdam, the Netherlands.; Department of Pediatric Immunology, Rheumatology, and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Johnson S; Sir William Dunn School of Pathology, Oxford, United Kingdom .
Lea SM; Sir William Dunn School of Pathology, Oxford, United Kingdom .; Central Oxford Structural Molecular Imaging Centre, Oxford, United Kingdom.
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Źródło :
MBio [mBio] 2021 Mar 23; Vol. 12 (2). Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immune Evasion*
Bacterial Proteins/*metabolism
Bordetella pertussis/*pathogenicity
Complement C1 Inhibitor Protein/*metabolism
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Binding Sites ; Blood Coagulation ; Bordetella pertussis/chemistry ; Bordetella pertussis/metabolism ; Complement C1 Inhibitor Protein/chemistry ; Complement System Proteins/metabolism ; Cryoelectron Microscopy ; Fibrinolysis ; Models, Molecular ; Mutation ; Protein Binding ; Protein Domains ; Type V Secretion Systems/genetics ; Type V Secretion Systems/metabolism ; Virulence
Czasopismo naukowe
Tytuł :
An immune epigenetic insight to COVID-19 infection.
Autorzy :
Jit BP; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
Qazi S; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
Arya R; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
Srivastava A; Regional Institute of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 220115, India.
Gupta N; National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Sharma A; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
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Źródło :
Epigenomics [Epigenomics] 2021 Mar; Vol. 13 (6), pp. 465-480. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Epigenesis, Genetic*
Immune Evasion*
COVID-19/*genetics
COVID-19/*immunology
Angiotensin-Converting Enzyme 2/genetics ; Antigen Presentation ; DNA Methylation ; HSP90 Heat-Shock Proteins/genetics ; Histones ; Humans ; SARS-CoV-2/physiology ; Virus Internalization
Czasopismo naukowe

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