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Wyszukujesz frazę ""Immunoglobulin Fab Fragments"" wg kryterium: Temat


Tytuł:
Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Autorzy:
Bruce HA; School of Pharmacy, University of Waterloo, Waterloo, Canada.
Singer AU; School of Pharmacy, University of Waterloo, Waterloo, Canada.
Filippova EV; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
Blazer LL; School of Pharmacy, University of Waterloo, Waterloo, Canada.
Adams JJ; School of Pharmacy, University of Waterloo, Waterloo, Canada.
Enderle L; School of Pharmacy, University of Waterloo, Waterloo, Canada.
Ben-David M; Ukko Inc., Rehovot, Israel.
Radley EH; Department of Biochemistry, University of Toronto, Toronto, Canada.
Mao DYL; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.
Pau V; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.
Orlicky S; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.
Sicheri F; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.; Departments of Biochemistry and Molecular Genetics, University of Toronto, Ontario, Canada.
Kurinov I; NE-CAT, Cornell University, Argonne, Illinois, USA.
Atwell S; Neurocrine Biosciences, San Diego, California, USA.
Kossiakoff AA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA.
Sidhu SS; School of Pharmacy, University of Waterloo, Waterloo, Canada.
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Źródło:
Protein science : a publication of the Protein Society [Protein Sci] 2024 Jan; Vol. 33 (1), pp. e4824.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/genetics
Immunoglobulin Fab Fragments*/chemistry
Antigen-Antibody Complex*/chemistry
Humans ; Crystallization/methods ; Antigens/chemistry ; Crystallography, X-Ray ; Protein Conformation
Czasopismo naukowe
Tytuł:
Stabilization of adalimumab Fab through the introduction of disulfide bonds between the variable and constant domains.
Autorzy:
Yoshikawa M; Faculty of Pharmaceutical Sciences, Sojo University, Japan.
Senda M; Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Japan.
Nakamura H; Faculty of Pharmaceutical Sciences, Sojo University, Japan.
Oda-Ueda N; Faculty of Pharmaceutical Sciences, Sojo University, Japan.
Ueda T; Graduate School of Pharmaceutical Sciences, Kyushu University, Japan.
Senda T; Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Japan; Department of Accelerator Science, School of High Energy Accelerator Science, SOKENDAI, Japan; Faculty of Pure and Applied Sciences, University of Tsukuba, Japan.
Ohkuri T; Faculty of Pharmaceutical Sciences, Sojo University, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Mar 12; Vol. 700, pp. 149592. Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/chemistry
Disulfides*/chemistry
Adalimumab/chemistry ; Protein Domains ; Temperature
Czasopismo naukowe
Tytuł:
pH-responsive multi-network composite cellulose-based hydrogels for stable delivery of oral IgY-Fab fragments.
Autorzy:
Xia M; Hubei Hongshan Laboratory, National Research and Development Centre for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China; Shenzhen Institute of Nutrition and Health, Huazhong Agricultural University, Wuhan 430070, China; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518000, China.
Cui Z; Hubei Hongshan Laboratory, National Research and Development Centre for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Zeng T; State Key Laboratory for Managing Biotic and Chemical Treats to the Quality and Safety of Agro-products, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Zhejiang, China.
Lu L; State Key Laboratory for Managing Biotic and Chemical Treats to the Quality and Safety of Agro-products, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Zhejiang, China. Electronic address: .
Sheng L; Hubei Hongshan Laboratory, National Research and Development Centre for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China.
Cai Z; Hubei Hongshan Laboratory, National Research and Development Centre for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China; Shenzhen Institute of Nutrition and Health, Huazhong Agricultural University, Wuhan 430070, China; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518000, China. Electronic address: .
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Źródło:
Food chemistry [Food Chem] 2024 Mar 01; Vol. 435, pp. 137567. Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*
Cellulose*/chemistry
Animals ; Hydrogels/chemistry ; Hydrogen-Ion Concentration ; Mammals
Czasopismo naukowe
Tytuł:
Cytoplasmic production of Fabs in chemically defined media in fed-batch fermentation.
Autorzy:
Castillo-Corujo A; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.
Saaranen MJ; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.
Ruddock LW; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland. Electronic address: .
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Źródło:
Protein expression and purification [Protein Expr Purif] 2024 Mar; Vol. 215, pp. 106404. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli*/genetics
Escherichia coli*/metabolism
Immunoglobulin Fab Fragments*/biosynthesis
Animals ; Cytoplasm/metabolism ; Disulfides/metabolism ; Fermentation ; Trastuzumab
Czasopismo naukowe
Tytuł:
Recombinant humanized Fab fragments targeting the CFC domain of human Cripto-1.
Autorzy:
Sandomenico A; Institute of Biostructures and Bioimaging, CNR, Via P. Castellino, 111, 80131, Napoli, Italy. Electronic address: .
Selis F; BIOVIIIX, via B. Brin 59c, Napoli, Italy.
Sivaccumar JP; Institute of Biostructures and Bioimaging, CNR, Via P. Castellino, 111, 80131, Napoli, Italy.
Olimpieri P; Department of Physics, Sapienza University, 00184, Rome, Italy.
Iaccarino E; Institute of Biostructures and Bioimaging, CNR, Via P. Castellino, 111, 80131, Napoli, Italy.
Cicatiello V; Institute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, Via P. Castellino, 111, 80131, Napoli, Italy.
Cantile M; BIOVIIIX, via B. Brin 59c, Napoli, Italy.
Sanna R; BIOVIIIX, via B. Brin 59c, Napoli, Italy.
Leonardi A; Department of Molecular Medicine and Medical Biotechnology, Italy.
De Falco S; Institute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, Via P. Castellino, 111, 80131, Napoli, Italy.
Ruvo M; Institute of Biostructures and Bioimaging, CNR, Via P. Castellino, 111, 80131, Napoli, Italy. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jan 29; Vol. 694, pp. 149417. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/chemistry
Neoplasms*
Animals ; Humans ; Mice ; Antibodies ; GPI-Linked Proteins/metabolism ; Intercellular Signaling Peptides and Proteins ; Neoplasm Proteins/metabolism
Czasopismo naukowe
Tytuł:
Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies.
Autorzy:
Gagné D; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Sarker M; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Gingras G; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Hodgson DJ; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Frahm G; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Creskey M; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Lorbetskie B; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Bigelow S; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Wang J; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Zhang X; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Johnston MJW; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.; Department of Chemistry, Carleton University, Ottawa, ON, Canada.
Lu H; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.
Aubin Y; Regulatory Research Division, Center for Oncology, Radiopharmaceuticals and Research, Health Canada, Ottawa, ON, Canada.; Department of Chemistry, Carleton University, Ottawa, ON, Canada.
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Źródło:
PloS one [PLoS One] 2023 Nov 29; Vol. 18 (11), pp. e0294406. Date of Electronic Publication: 2023 Nov 29 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/genetics
Immunoglobulin Fab Fragments*/chemistry
Escherichia coli*/genetics
Pichia ; Adalimumab/therapeutic use ; Carbon Isotopes ; Antibodies, Monoclonal ; Trastuzumab
SCR Organism:
Komagataella phaffii; Komagataella pastoris
Czasopismo naukowe
Tytuł:
The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum.
Autorzy:
Larsen HA; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
Atkins WM; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
Nath A; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
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Źródło:
Protein science : a publication of the Protein Society [Protein Sci] 2023 Dec; Vol. 32 (12), pp. e4812.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal*/chemistry
Immunoglobulin Fab Fragments*
Humans
Czasopismo naukowe
Tytuł:
The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function.
Autorzy:
Lyu M; Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Malyutin AG; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.; Beckman Institute, California Institute of Technology, Pasadena, CA, 91125, USA.; Takeda Pharmaceuticals, Cambridge, MA, 02139, USA.
Stadtmueller BM; Department of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Department of Biomedical and Translational Sciences, Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Center for Biophysics and Quantitative Biology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Nov 21; Vol. 14 (1), pp. 7583. Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*
Immunoglobulin M*
Fishes*/immunology
Animals ; Cryoelectron Microscopy
Czasopismo naukowe
Tytuł:
Epitope-Based Specific Antibody Modifications.
Autorzy:
Horie S; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Mishiro K; Institute for Frontier Science Initiative, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Nishino M; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Domae I; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Wakasugi M; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Matsunaga T; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.
Kunishima M; Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan.; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
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Źródło:
Bioconjugate chemistry [Bioconjug Chem] 2023 Nov 15; Vol. 34 (11), pp. 2022-2033. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*/chemistry
Immunoglobulin Fab Fragments*
Epitopes/chemistry ; Antibody Affinity
Czasopismo naukowe
Tytuł:
Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Autorzy:
Borowska MT; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
Boughter CT; Graduate Program in Biophysical Sciences, University of Chicago, Chicago, IL 60637, USA.
Bunker JJ; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Department of Pathology, University of Chicago, Chicago, IL 60637, USA.
Guthmiller JJ; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
Wilson PC; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.
Roux B; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
Bendelac A; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Department of Pathology, University of Chicago, Chicago, IL 60637, USA.
Adams EJ; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA; Committee on Immunology, University of Chicago, Chicago, IL 60637, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2023 Oct 31; Vol. 42 (10), pp. 113190. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Antibodies, Monoclonal*
Immunoglobulin Fab Fragments*
Epitopes
Czasopismo naukowe
Tytuł:
Crystal structures and molecular dynamics simulations of a humanised antibody fragment at acidic to basic pH.
Autorzy:
Tang J; UCL School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Zhang C; Department of Biochemical Engineering, UCL, Bernard Katz Building, Gower Street, London, WC1E 6BT, UK.
Castillo NC; Department of Biochemical Engineering, UCL, Bernard Katz Building, Gower Street, London, WC1E 6BT, UK.
Lalaurie CJ; Department of Biochemical Engineering, UCL, Bernard Katz Building, Gower Street, London, WC1E 6BT, UK.
Gao X; Division of Biosciences, Department of Structural and Molecular Biology, UCL, London, WC1E 6BT, UK.
Dalby PA; Department of Biochemical Engineering, UCL, Bernard Katz Building, Gower Street, London, WC1E 6BT, UK. .
Kozielski F; UCL School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, UK. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 28; Vol. 13 (1), pp. 16281. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Dynamics Simulation*
Immunoglobulin Fab Fragments*/chemistry
Humans ; X-Ray Diffraction ; Protein Conformation ; Scattering, Small Angle
Czasopismo naukowe
Tytuł:
Cross-linking disulfide bonds govern solution structures of diabodies.
Autorzy:
Math BA; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Waibl F; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Lamp LM; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Fernández-Quintero ML; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Liedl KR; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
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Źródło:
Proteins [Proteins] 2023 Sep; Vol. 91 (9), pp. 1316-1328. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies*
Immunoglobulin Fab Fragments*/chemistry
Protein Conformation ; Binding Sites, Antibody ; Disulfides
Czasopismo naukowe
Tytuł:
Genotyped functional screening of soluble Fab clones enables in-depth analysis of mutation effects.
Autorzy:
Oksanen S; Department of Life Sciences, University of Turku, 20520, Turku, Finland. .
Saarinen R; Department of Life Sciences, University of Turku, 20520, Turku, Finland.
Korkiakoski A; Department of Life Sciences, University of Turku, 20520, Turku, Finland.
Lamminmäki U; Department of Life Sciences, University of Turku, 20520, Turku, Finland.
Huovinen T; Department of Life Sciences, University of Turku, 20520, Turku, Finland. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 11; Vol. 13 (1), pp. 13107. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*
Immunoglobulin Fab Fragments*/chemistry
Mutation ; Cell Surface Display Techniques ; Peptide Library
Czasopismo naukowe
Tytuł:
Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Autorzy:
Davies AM; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Beavil RL; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Barbolov M; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Sandhar BS; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Gould HJ; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Beavil AJ; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
Sutton BJ; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom.
McDonnell JM; King's College London, Randall Centre for Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom. Electronic address: .
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Źródło:
Molecular immunology [Mol Immunol] 2023 Jul; Vol. 159, pp. 28-37. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoglobulin Fab Fragments*
Immunoglobulin Isotypes*
Animals ; Humans ; Mammals
Czasopismo naukowe
Tytuł:
Structural mechanism of Fab domain dissociation as a measure of interface stability.
Autorzy:
Pomarici ND; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Waibl F; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Quoika PK; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.; Center for Protein Assemblies (CPA), Physics Department, Chair of Theoretical Biophysics, Technical University of Munich, Ernst-Otto-Fischer-Str. 8, 85748, Garching, Germany.
Bujotzek A; Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Nonnenwald 2, 82377, Penzberg, Germany.
Georges G; Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Nonnenwald 2, 82377, Penzberg, Germany.
Fernández-Quintero ML; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria. .
Liedl KR; Institute of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria. .
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Źródło:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2023 Apr; Vol. 37 (4), pp. 201-215. Date of Electronic Publication: 2023 Mar 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoglobulin Fab Fragments*/chemistry
Immunoglobulin Fab Fragments*/metabolism
Antibodies*
Czasopismo naukowe
Tytuł:
Backbone NMR assignment of the yeast expressed Fab fragment of the NISTmAb reference antibody.
Autorzy:
Solomon TL; Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, MD, 20850, USA.
Chao K; Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, MD, 20850, USA.
Gingras G; Centre for Oncology, Radiopharmaceuticals and Research, Biologics and Radiotherapeutic Drugs Directorate, Health Canada, 251 Sir Frederick Banting Driveway, K1A 0K9, Ottawa, ON, Canada.
Aubin Y; Centre for Oncology, Radiopharmaceuticals and Research, Biologics and Radiotherapeutic Drugs Directorate, Health Canada, 251 Sir Frederick Banting Driveway, K1A 0K9, Ottawa, ON, Canada.
O'Dell WB; Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, MD, 20850, USA.
Marino JP; Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, MD, 20850, USA.
Brinson RG; Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, MD, 20850, USA. .
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Źródło:
Biomolecular NMR assignments [Biomol NMR Assign] 2023 Jun; Vol. 17 (1), pp. 75-81. Date of Electronic Publication: 2023 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/chemistry
Saccharomyces cerevisiae*
Nuclear Magnetic Resonance, Biomolecular ; Antibodies, Monoclonal/chemistry ; Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł:
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids.
Autorzy:
Eronen V; Department of Chemistry, University of Eastern Finland, PO BOX 111, 80100 Joensuu, Finland.
Tullila A; VTT Technical Research Centre of Finland Ltd, Tietotie 2, 02150 Espoo, Finland.
Iljin K; VTT Technical Research Centre of Finland Ltd, Tietotie 2, 02150 Espoo, Finland.
Rouvinen J; Department of Chemistry, University of Eastern Finland, PO BOX 111, 80100 Joensuu, Finland.
Nevanen TK; VTT Technical Research Centre of Finland Ltd, Tietotie 2, 02150 Espoo, Finland.
Hakulinen N; Department of Chemistry, University of Eastern Finland, PO BOX 111, 80100 Joensuu, Finland. Electronic address: .
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Źródło:
Journal of structural biology [J Struct Biol] 2023 Jun; Vol. 215 (2), pp. 107966. Date of Electronic Publication: 2023 Apr 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoglobulin Fab Fragments*/chemistry
Glucocorticoids*
Amino Acid Sequence ; Hydrocortisone ; Models, Molecular ; Crystallography, X-Ray ; Protein Conformation
Czasopismo naukowe
Tytuł:
Enhanced Thermal Stability and Reduced Aggregation in an Antibody Fab Fragment at Elevated Concentrations.
Autorzy:
Zhang C; Department of Biochemical Engineering, University College London, Gower Street, London WC1E 6BT, U.K.
Bye JW; School of Chemical Engineering and Analytical Science, The University of Manchester, Sackville Street, Manchester M13 9PL, U.K.
Lui LH; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, U.K.
Zhang H; Department of Biochemical Engineering, University College London, Gower Street, London WC1E 6BT, U.K.
Hales J; Department of Biochemical Engineering, University College London, Gower Street, London WC1E 6BT, U.K.
Brocchini S; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, U.K.
Curtis RA; School of Chemical Engineering and Analytical Science, The University of Manchester, Sackville Street, Manchester M13 9PL, U.K.
Dalby PA; Department of Biochemical Engineering, University College London, Gower Street, London WC1E 6BT, U.K.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2023 May 01; Vol. 20 (5), pp. 2650-2661. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoglobulin Fab Fragments*
Entropy ; Protein Stability
Czasopismo naukowe
Tytuł:
Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone.
Autorzy:
Miyagi H; R&D Division, Kyowa Kirin Co. Ltd, Tokyo, Japan.
Suzuki M; R&D Division, Kyowa Kirin Co. Ltd, Shizuoka, Japan.
Yasunaga M; CMC R&D Center, Kyowa Kirin Co. Ltd, Shizuoka, Japan.
Asada H; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iwata S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Saito JI; R&D Division, Kyowa Kirin Co. Ltd, Shizuoka, Japan.
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Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2023 May 01; Vol. 79 (Pt 5), pp. 435-441. Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, G-Protein-Coupled*/chemistry
Immunoglobulin Fab Fragments*/chemistry
Crystallization ; Protein Structure, Secondary ; Escherichia coli ; Epitopes
Czasopismo naukowe
Tytuł:
Successful management of massive digoxin overdose using DIGIFab and therapeutic plasma exchange: a case report.
Autorzy:
Alhussein RM; Department of Emergency Medicine, King Saud University, Medical City, Riyadh, Saudi Arabia. .
Alamri NA; Department of Emergency Medicine, King Saud University, Medical City, Riyadh, Saudi Arabia.
Alhashem HM; Department of Emergency Medicine, King Saud University, Medical City, Riyadh, Saudi Arabia.
Alarifi MI; Department of Critical Care Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Alyahya B; Department of Emergency Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
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Źródło:
Journal of medical case reports [J Med Case Rep] 2024 Mar 05; Vol. 18 (1), pp. 135. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Plasma Exchange*
Plasmapheresis*
Male ; Humans ; Adolescent ; Immunoglobulin Fab Fragments ; Digoxin
Czasopismo naukowe

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