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Wyświetlanie 61-80 z 2296
Tytuł:
A rare case of secondary cutaneous lymphoplasmacytic lymphoma clinically presenting as acquired cutis laxa.
Autorzy:
Lim, Dong Jun
Yang, Hee Joo
Lee, Mi Young
Lee, Woo Jin
Won, Chong Hyun
Chang, Sung Eun
Lee, Mi Woo
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Temat:
WALDENSTROM'S macroglobulinemia
CUTIS laxa
EXTRAMEDULLARY diseases
IMMUNOGLOBULIN heavy chains
NON-Hodgkin's lymphoma
AXILLA
Źródło:
Journal of Cutaneous Pathology; Feb2024, Vol. 51 Issue 2, p135-139, 5p
Czasopismo naukowe
Szczegóły
Tytuł:
Application of camelid heavy-chain variable domains (VHHs) in prevention and treatment of bacterial and viral infections.
Autorzy:
Wilken L; a School of Pharmacy and Life Sciences , Robert Gordon University , Garthdee Road, Aberdeen , United Kingdom.; b Department of Natural Sciences , Hochschule Bonn-Rhein-Sieg , Rheinbach , Germany.
McPherson A; a School of Pharmacy and Life Sciences , Robert Gordon University , Garthdee Road, Aberdeen , United Kingdom.
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Źródło:
International reviews of immunology [Int Rev Immunol] 2018 Jan 02; Vol. 37 (1), pp. 69-76. Date of Electronic Publication: 2017 Nov 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bacterial Infections/*prevention & control
Camelidae/*immunology
Immunoglobulin Heavy Chains/*therapeutic use
Immunoglobulin Variable Region/*therapeutic use
Virus Diseases/*prevention & control
Animals ; Bacterial Infections/immunology ; Bacterial Infections/therapy ; Camelidae/genetics ; Dental Caries/microbiology ; Dental Caries/therapy ; Diarrhea/microbiology ; Diarrhea/prevention & control ; Escherichia coli Infections/prevention & control ; Humans ; Immunization, Passive ; Immunoglobulin Heavy Chains/biosynthesis ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Variable Region/biosynthesis ; Immunoglobulin Variable Region/genetics ; Lipopolysaccharides/antagonists & inhibitors ; Lipopolysaccharides/toxicity ; Poliomyelitis/prevention & control ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/genetics ; Recombinant Proteins/therapeutic use ; Respiratory Syncytial Virus Infections/therapy ; Streptococcus mutans/immunology ; Virus Diseases/immunology ; Virus Diseases/therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Autopsy case with concurrent transthyretin and immunoglobulin amyloidosis.
Autorzy:
Shintani-Domoto Y; Department of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, Japan.
Ishino K; Department of Integrated Diagnostic Pathology, Nippon Medical School, Tokyo, Japan.
Naiki H; Department of Molecular Pathology, University of Fukui, Fukui, Japan.
Sakatani T; Department of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, Japan.
Ohashi R; Department of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, Japan.; Department of Integrated Diagnostic Pathology, Nippon Medical School, Tokyo, Japan.
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Źródło:
Pathology international [Pathol Int] 2022 Jan; Vol. 72 (1), pp. 65-71. Date of Electronic Publication: 2021 Oct 12.
Typ publikacji:
Case Reports
MeSH Terms:
Amyloidosis*/diagnosis
Amyloidosis*/pathology
Autopsy*
Immunoglobulins/*metabolism
Prealbumin/*metabolism
Aged, 80 and over ; Amyloid/metabolism ; Chromatography, Liquid ; Diagnosis, Differential ; Humans ; Immunoglobulin Heavy Chains/metabolism ; Immunoglobulin Light Chains/metabolism ; Kidney/metabolism ; Kidney/pathology ; Lung/metabolism ; Lung/pathology ; Male ; Multiple Myeloma/diagnosis ; Multiple Myeloma/pathology ; Myocardium/metabolism ; Myocardium/pathology ; Tandem Mass Spectrometry
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A new approach to produce IgG 4 -like bispecific antibodies.
Autorzy:
Zhao C; School of Pharmacy, Fudan University, Shanghai, 201203, China.; China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
Zhang W; China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
Gong G; China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
Xie L; China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
Wang MW; School of Pharmacy, Fudan University, Shanghai, 201203, China. .; The National Center for Drug Screening, Shanghai, 201203, China. .
Hu Y; China State Institute of Pharmaceutical Industry, Shanghai, 201203, China. .
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Źródło:
Scientific reports [Sci Rep] 2021 Sep 20; Vol. 11 (1), pp. 18630. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific/*biosynthesis
Immunoglobulin G/*biosynthesis
Amino Acid Substitution ; Animals ; Antibodies, Bispecific/chemistry ; Antibodies, Bispecific/genetics ; Antibodies, Monoclonal/biosynthesis ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal, Humanized/biosynthesis ; Antibodies, Monoclonal, Humanized/chemistry ; Antibodies, Monoclonal, Humanized/genetics ; Antigens, CD/immunology ; HEK293 Cells ; Humans ; Immunoglobulin G/chemistry ; Immunoglobulin G/genetics ; Immunoglobulin Heavy Chains/biosynthesis ; Immunoglobulin Heavy Chains/chemistry ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Light Chains/biosynthesis ; Immunoglobulin Light Chains/chemistry ; Immunoglobulin Light Chains/genetics ; In Vitro Techniques ; Male ; Models, Molecular ; Mutagenesis, Site-Directed ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/immunology ; Protein Engineering/methods ; Protein Multimerization ; Protein Stability ; Rats ; Rats, Sprague-Dawley ; Static Electricity ; Lymphocyte Activation Gene 3 Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques.
Autorzy:
Berendam SJ; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Morgan-Asiedu PK; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Mangan RJ; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Li SH; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Heimsath H; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Luo K; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Curtis AD 2nd; Department of Microbiology and Immunology, Children's Research Institute and Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Eudailey JA; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Pediatrics, Weill Cornell College of Medicine, New York City, New York, United States of America.
Fox CB; Infectious Disease Research Institute (IDRI), Seattle, Washington State, United States of America.; Department of Global Health, University of Washington, Seattle, Washington State, United States of America.
Tomai MA; 3M Center, 3 M Drug Delivery Systems, St. Paul, Minnesota, United States of America.
Phillips B; Department of Microbiology and Immunology, Children's Research Institute and Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Itell HL; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Kunz E; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Hudgens M; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Cronin K; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Wiehe K; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Alam SM; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Van Rompay KKA; California National Primate Research Center, University of California at Davis, Davis, California, United States of America.
De Paris K; Department of Microbiology and Immunology, Children's Research Institute and Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Permar SR; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Pediatrics, Weill Cornell College of Medicine, New York City, New York, United States of America.
Moody MA; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Fouda GG; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Dec 31; Vol. 16 (12), pp. e0256885. Date of Electronic Publication: 2021 Dec 31 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
AIDS Vaccines/*blood
AIDS Vaccines/*immunology
Adjuvants, Immunologic/*pharmacology
Antibody Formation/*immunology
Receptors, Antigen, B-Cell/*metabolism
env Gene Products, Human Immunodeficiency Virus/*immunology
Animals ; Antibody Formation/drug effects ; Child ; Complementarity Determining Regions ; Epitopes/immunology ; Humans ; Immunization ; Immunoglobulin Heavy Chains/metabolism ; Immunologic Memory/drug effects ; Macaca mulatta ; Somatic Hypermutation, Immunoglobulin ; Toll-Like Receptors/agonists ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reliable IGHV status assessment by next generation sequencing in routine practice for chronic lymphocytic leukemia.
Autorzy:
Boulland ML; Laboratoire d'Hématologie, Pôle de Biologie, CHU de Rennes, Rennes, France.; INSERM, UMR1236, Equipe labellisée Ligue contre le Cancer, Rennes, France.
Vic S; Service d'Hématologie Clinique, CHU de Rennes, Rennes, France.
Thonier F; INRIA, Rennes, France.
Ganard M; Service d'Hématologie Clinique, CHU de Rennes, Rennes, France.
Lamy T; INSERM, UMR1236, Equipe labellisée Ligue contre le Cancer, Rennes, France.; Service d'Hématologie Clinique, CHU de Rennes, Rennes, France.
Fest T; Laboratoire d'Hématologie, Pôle de Biologie, CHU de Rennes, Rennes, France.; INSERM, UMR1236, Equipe labellisée Ligue contre le Cancer, Rennes, France.
Guibert S; Service d'Hématologie Clinique, CHU de Rennes, Rennes, France.
Pastoret C; Laboratoire d'Hématologie, Pôle de Biologie, CHU de Rennes, Rennes, France.; INSERM, UMR1236, Equipe labellisée Ligue contre le Cancer, Rennes, France.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2021 Nov; Vol. 62 (11), pp. 2800-2803. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji:
Letter
MeSH Terms:
Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
High-Throughput Nucleotide Sequencing ; Humans ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Variable Region/genetics ; Mutation ; Prognosis
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular engineering and plant expression of an immunoglobulin heavy chain scaffold for delivery of a dengue vaccine candidate.
Autorzy:
Kim MY; Institute for Infection and Immunity, St George's University of London, London, UK.; Department of Molecular Biology and The Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju, Korea.
Van Dolleweerd C; Institute for Infection and Immunity, St George's University of London, London, UK.
Copland A; Institute for Infection and Immunity, St George's University of London, London, UK.
Paul MJ; Institute for Infection and Immunity, St George's University of London, London, UK.
Hofmann S; Institute for Infection and Immunity, St George's University of London, London, UK.
Webster GR; Institute for Infection and Immunity, St George's University of London, London, UK.
Julik E; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Ceballos-Olvera I; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Reyes-Del Valle J; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Yang MS; Department of Molecular Biology and The Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju, Korea.
Jang YS; Department of Molecular Biology and The Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju, Korea.
Reljic R; Institute for Infection and Immunity, St George's University of London, London, UK.
Ma JK; Institute for Infection and Immunity, St George's University of London, London, UK.
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Źródło:
Plant biotechnology journal [Plant Biotechnol J] 2017 Dec; Vol. 15 (12), pp. 1590-1601. Date of Electronic Publication: 2017 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Dengue Vaccines/*pharmacology
Immunoglobulin Heavy Chains/*genetics
Protein Engineering/*methods
Recombinant Proteins/*immunology
Animals ; CHO Cells ; Cricetulus ; Dengue Vaccines/administration & dosage ; Dengue Vaccines/genetics ; Female ; Gene Expression Regulation, Plant ; Humans ; Immunoglobulin Heavy Chains/immunology ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Mice, Inbred BALB C ; Neutralization Tests ; Plants, Genetically Modified/genetics ; Protein Domains ; Recombinant Proteins/genetics ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Nicotiana/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Purification and quantification of heavy-chain antibodies from the milk of bactrian camels.
Autorzy:
Yao H; Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Huhhot, China.
Zhang M; Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, College of Food Science and Engineering, Inner Mongolia Agricultural University, Huhhot, China.
Li Y; Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, College of Food Science and Engineering, Inner Mongolia Agricultural University, Huhhot, China.
Yao J; Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, College of Food Science and Engineering, Inner Mongolia Agricultural University, Huhhot, China.
Meng H; Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China.
Yu S; Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Huhhot, China.
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Źródło:
Animal science journal = Nihon chikusan Gakkaiho [Anim Sci J] 2017 Sep; Vol. 88 (9), pp. 1446-1450. Date of Electronic Publication: 2017 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Camelus/*immunology
Immunoglobulin G/*isolation & purification
Immunoglobulin Heavy Chains/*isolation & purification
Milk/*immunology
Animals ; Blotting, Western ; Chromatography, Affinity ; Electrophoresis, Polyacrylamide Gel ; Immunoglobulin G/analysis ; Immunoglobulin Heavy Chains/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis.
Autorzy:
Klimtchuk ES; a Gerry Amyloidosis Research Laboratory, Amyloidosis Center , Boston University School of Medicine , Boston , MA , USA.
Prokaeva TB; a Gerry Amyloidosis Research Laboratory, Amyloidosis Center , Boston University School of Medicine , Boston , MA , USA.
Spencer BH; a Gerry Amyloidosis Research Laboratory, Amyloidosis Center , Boston University School of Medicine , Boston , MA , USA.
Gursky O; a Gerry Amyloidosis Research Laboratory, Amyloidosis Center , Boston University School of Medicine , Boston , MA , USA.; b Department of Physiology and Biophysics , Boston University School of Medicine , Boston , MA , USA.
Connors LH; a Gerry Amyloidosis Research Laboratory, Amyloidosis Center , Boston University School of Medicine , Boston , MA , USA.; c Department of Pathology and Laboratory Medicine , Boston University School of Medicine , Boston , MA , USA.
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Źródło:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2017 Jun; Vol. 24 (2), pp. 115-122. Date of Electronic Publication: 2017 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Amyloid/*metabolism
Immunoglobulin Heavy Chains/*biosynthesis
Immunoglobulin Light Chains/*biosynthesis
Immunoglobulin Light-chain Amyloidosis/*metabolism
Immunoglobulin Variable Region/*biosynthesis
Aged ; Amyloid/genetics ; Animals ; Female ; Humans ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Light Chains/genetics ; Immunoglobulin Light-chain Amyloidosis/genetics ; Immunoglobulin Light-chain Amyloidosis/pathology ; Immunoglobulin Variable Region/genetics ; Male ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cancer-Cell-Derived IgG and Its Potential Role in Tumor Development.
Autorzy:
Kdimati S; Clinic of General Surgery, Molecular Oncology and Immunotherapy, University Medical Center Rostock, University of Rostock, 18057 Rostock, Germany.
Mullins CS; Clinic of General Surgery, Molecular Oncology and Immunotherapy, University Medical Center Rostock, University of Rostock, 18057 Rostock, Germany.
Linnebacher M; Clinic of General Surgery, Molecular Oncology and Immunotherapy, University Medical Center Rostock, University of Rostock, 18057 Rostock, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 27; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immunoglobulin G/*immunology
Neoplasms/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Antibody-Dependent Cell Cytotoxicity/immunology ; B-Lymphocytes/immunology ; Complement Activation/immunology ; Humans ; Immunoglobulin Heavy Chains/immunology ; Phagocytosis/immunology ; Receptors, IgG/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A hybridoma-derived monoclonal antibody with high homology to the aberrant myeloma light chain.
Autorzy:
Pornnoppadol G; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America.; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
Zhang B; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States of America.
Desai AA; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America.
Berardi A; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Macromolecular Science & Engineering, University of Michigan, Ann Arbor, Michigan, United States of America.
Remmer HA; Proteomics & Peptide Synthesis Core, University of Michigan, Ann Arbor, Michigan, United States of America.
Tessier PM; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan, United States of America.; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America.
Greineder CF; BioInterfaces Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Oct 11; Vol. 16 (10), pp. e0252558. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal/*genetics
Hybridomas/*physiology
Immunoglobulin Light Chains/*genetics
Multiple Myeloma/*genetics
Amino Acid Sequence ; Animals ; CHO Cells ; Cell Line ; Cloning, Molecular/methods ; Cricetulus ; DNA, Complementary/genetics ; Frameshift Mutation/genetics ; Genes, Immunoglobulin/genetics ; HEK293 Cells ; Humans ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Variable Region/genetics ; Mice ; Recombinant Proteins/genetics ; Tetraspanin 30/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Insights into Comparative Modeling of V H H Domains.
Autorzy:
Vattekatte AM; Biologie Intégrée du Globule Rouge UMR_S1134, Inserm, Laboratoire d'Excellence GR-Ex, Université de la Réunion, F-97715 Saint Denis Messag, France.
Cadet F; Biologie Intégrée du Globule Rouge UMR_S1134, Inserm, Laboratoire d'Excellence GR-Ex, Université de la Réunion, F-97715 Saint Denis Messag, France.
Gelly JC; Biologie Intégrée du Globule Rouge UMR_S1134, Inserm, Laboratoire d'Excellence GR-Ex, Université de Paris, F-75739 Paris, France.
de Brevern AG; Biologie Intégrée du Globule Rouge UMR_S1134, Inserm, Laboratoire d'Excellence GR-Ex, Université de Paris, F-75739 Paris, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 09; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Molecular*
Protein Conformation*
Immunoglobulin Heavy Chains/*chemistry
Immunoglobulin Variable Region/*chemistry
Amino Acid Sequence ; Complementarity Determining Regions/chemistry ; Humans ; Protein Binding ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High-throughput sequencing of immunoglobulin heavy chain for minimal residual disease detection in B-lymphoblastic leukemia.
Autorzy:
Correia RP; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Puga RD; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Muto NH; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Lee MLM; Grupo de Apoio ao Adolescente e a Criança com Câncer, São Paulo, Brazil.
Torres DC; Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Hassan R; Bone Marrow Transplantation Center, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Bacal NS; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.; Centro de Hematologia de São Paulo, São Paulo, Brazil.
Hamerschlak N; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Campregher PV; Departments of Clinical Pathology Laboratory, Hematology and Hemotherapy, Research Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2021 Aug; Vol. 43 (4), pp. 724-731. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Heavy Chains/*genetics
Neoplasm, Residual/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
High-Throughput Nucleotide Sequencing ; Humans ; Neoplasm, Residual/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intensity of antigen expression reflects IGHV mutational status and Dohner-defined prognostic categories in chronic lymphocytic leukemia, monoclonal B-cell lymphocytosis, and small lymphocytic lymphoma.
Autorzy:
Balakrishna J; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.; Department of Hematopathology, Ohio State University Wexner Medical Center, Columbus, OH, USA.
Basumallik N; Hematology Branch, NHLBI, NIH, Bethesda, MD, USA.
Matulonis R; Walter Reed National Military Medical Center, Bethesda, MD, USA.
Scott D; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Salem D; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Jasper G; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Wiestner A; Hematology Branch, NHLBI, NIH, Bethesda, MD, USA.
Stetler-Stevenson M; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
Marti G; Hematology Branch, NHLBI, NIH, Bethesda, MD, USA.
Sun C; Hematology Branch, NHLBI, NIH, Bethesda, MD, USA.
Yuan CM; Laboratory of Pathology, Department of Flow Cytometry, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2021 Aug; Vol. 62 (8), pp. 1828-1839. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:
Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
Lymphocytosis*/diagnosis
Lymphocytosis*/genetics
B-Lymphocytes ; Humans ; Immunoglobulin Heavy Chains/genetics ; Mutation ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antibody affinity maturation through combining display of two-chain paired antibody and precision flow cytometric sorting.
Autorzy:
Sun S; Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100039, China.
Yang X; CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Wang H; College of Life Sciences, North China University of Science and Technology, Tangshan, Hebei Province, 063000, China.
Zhao Y; Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Lin Y; Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Ye C; Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Fang X; CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Hang H; Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. .; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. .
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Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2016 Jul; Vol. 100 (13), pp. 5977-88. Date of Electronic Publication: 2016 May 03.
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Flow Cytometry/*methods
Immunoglobulin Heavy Chains/*immunology
Immunoglobulin Light Chains/*immunology
Antibodies/chemistry ; Antibodies/genetics ; Antibodies/immunology ; Antibody Affinity ; Immunoglobulin Heavy Chains/chemistry ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Light Chains/chemistry ; Immunoglobulin Light Chains/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Treatment of Chronic Lymphocytic Leukemia in the Personalized Medicine Era.
Autorzy:
Sánchez Suárez, María Del Mar (AUTHOR)
Martín Roldán, Alicia (AUTHOR)
Alarcón-Payer, Carolina (AUTHOR)
Rodríguez-Gil, Miguel Ángel (AUTHOR)
Poquet-Jornet, Jaime Eduardo (AUTHOR)
Puerta Puerta, José Manuel (AUTHOR)
Jiménez Morales, Alberto (AUTHOR)
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Źródło:
Pharmaceutics. Jan2024, Vol. 16 Issue 1, p55. 38p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of diagnostic antibodies against immunoglobulin heavy chain variable region for heavy chain amyloidosis (AH amyloidosis).
Autorzy:
Nakagawa, Mayuko (AUTHOR)
Yazaki, Masahide (AUTHOR)
Kametani, Fuyuki (AUTHOR)
Katoh, Nagaaki (AUTHOR)
Yoshinaga, Tsuneaki (AUTHOR)
Higuchi, Keiichi (AUTHOR)
Sekijima, Yoshiki (AUTHOR)
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Źródło:
Pathology International. Apr2021, Vol. 71 Issue 4, p245-254. 10p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IgH 3' regulatory region increases ectopic class switch recombination.
Autorzy:
Le Noir, Sandrine (AUTHOR)
Bonaud, Amélie (AUTHOR)
Hervé, Bastien (AUTHOR)
Baylet, Audrey (AUTHOR)
Boyer, François (AUTHOR)
Lecardeur, Sandrine (AUTHOR)
Oruc, Zeliha (AUTHOR)
Sirac, Christophe (AUTHOR)
Cogné, Michel (AUTHOR)
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Źródło:
PLoS Genetics. 2/8/2021, Vol. 17 Issue 2, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Germline-Encoded Structural Arginine Trap Underlies the Anti-DNA Reactivity of a Murine V Gene Segment.
Autorzy:
Dos Santos Araújo RP; Department of Cellular Biology, Institute of Biology, University of Brasilia, Brasilia 70910-900, Brazil.
França RKA; Department of Cellular Biology, Institute of Biology, University of Brasilia, Brasilia 70910-900, Brazil.
Valadares NF; Department of Cellular Biology, Institute of Biology, University of Brasilia, Brasilia 70910-900, Brazil.
Maranhão AQ; Department of Cellular Biology, Institute of Biology, University of Brasilia, Brasilia 70910-900, Brazil.; Instituto Nacional de Ciência e Tecnologia (iii-INCT), São Paulo 05403-000, Brazil.
Brigido MM; Department of Cellular Biology, Institute of Biology, University of Brasilia, Brasilia 70910-900, Brazil.; Instituto Nacional de Ciência e Tecnologia (iii-INCT), São Paulo 05403-000, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 26; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Variable Region/*genetics
Single-Domain Antibodies/*genetics
Single-Domain Antibodies/*immunology
Amino Acid Sequence/genetics ; Animals ; Antibodies, Antinuclear/genetics ; Arginine/genetics ; Arginine/metabolism ; Autoantigens/genetics ; Autoimmunity/immunology ; Base Sequence/genetics ; DNA/immunology ; Germ Cells/immunology ; Humans ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Heavy Chains/metabolism ; Immunoglobulin Variable Region/metabolism ; Immunoglobulin Variable Region/ultrastructure ; Mice ; Single-Domain Antibodies/ultrastructure ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 61-80 z 2296

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