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Wyszukujesz frazę ""Immunology"" wg kryterium: Temat


Starter badań:

Tytuł:
Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022.
Autorzy:
Yuan X; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Shi J; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Peng Z; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Peng L; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Zhou S; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Wu C; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Zhao J; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Xu D; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Li M; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Wang Q; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China. wangqian_.; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China. wangqian_.; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China. wangqian_.; State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China. wangqian_.
Zeng X; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China. .; National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Beijing, China. .; State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China. .; State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China. .
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Źródło:
Clinical rheumatology [Clin Rheumatol] 2024 Mar; Vol. 43 (3), pp. 1111-1126. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmune Diseases*/immunology
Autoimmune Diseases*/virology
Interferon-Induced Helicase, IFIH1*/immunology
RNA, Viral*/immunology
Humans ; Autoantibodies/immunology ; Bibliometrics ; China ; Double Stranded RNA Viruses/immunology ; RNA, Double-Stranded/immunology ; United States
Czasopismo naukowe
Tytuł:
A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs.
Autorzy:
English K; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; VIB-UGent Center for Inflammation Research, Ghent, Belgium.
Kwan R; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Holz LE; Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
McGuffog C; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Krol JMM; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands.
Kempe D; EMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
Kaisho T; Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Heath WR; Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Lisowski L; Children's Medical Research Institute, Translational Vectorology Research Unit, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warsaw, Poland.
Biro M; EMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
McCaughan GW; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Bowen DG; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. .
Bertolino P; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 10; Vol. 15 (1), pp. 1261. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/immunology
Liver*/immunology
Lymphoid Tissue*/immunology
Antigens ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Humans
Czasopismo naukowe
Tytuł:
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
Autorzy:
Deng Z; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Loyher PL; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lazarov T; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
Li L; Graduate Center, City University of New York, New York, NY, USA.
Shen Z; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
Bhinder B; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell, New York, NY, USA.
Yang H; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhong Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Alberdi A; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Massague J; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sun JC; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Benezra R; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Glass CK; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Elemento O; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell, New York, NY, USA.
Iacobuzio-Donahue CA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Geissmann F; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. .; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (8000), pp. 864-873. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Inhibitor of Differentiation Proteins*/deficiency
Inhibitor of Differentiation Proteins*/genetics
Inhibitor of Differentiation Proteins*/metabolism
Kupffer Cells*/cytology
Kupffer Cells*/immunology
Kupffer Cells*/metabolism
Neoplasms*/immunology
Neoplasms*/pathology
Neoplasms*/therapy
Animals ; Humans ; Mice ; Bone Marrow Cells/cytology ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; Cell Lineage ; Induced Pluripotent Stem Cells/cytology ; Killer Cells, Natural/cytology ; Killer Cells, Natural/immunology ; Liver/immunology ; Liver/pathology ; Macrophage Activation ; Neoplasm Proteins ; Phagocytosis
Czasopismo naukowe
Tytuł:
Naturally occurring T cell mutations enhance engineered T cell therapies.
Autorzy:
Garcia J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Moonlight Bio, Seattle, WA, USA.
Daniels J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Moonlight Bio, Seattle, WA, USA.
Lee Y; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Zhu I; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Cheng K; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Liu Q; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Goodman D; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Burnett C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Law C; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Thienpont C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Alavi J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Azimi C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Montgomery G; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Roybal KT; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA. .; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, USA. .; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. .; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA. .; Gladstone-UCSF Institute for Genomic Immunology, San Francisco, CA, USA. .; UCSF Cell Design Institute, San Francisco, CA, USA. .
Choi J; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA. .; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7999), pp. 626-634. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Evolution, Molecular*
Immunotherapy, Adoptive*/methods
Lymphoma, T-Cell, Cutaneous*/genetics
Lymphoma, T-Cell, Cutaneous*/immunology
Lymphoma, T-Cell, Cutaneous*/pathology
Lymphoma, T-Cell, Cutaneous*/therapy
Mutation*
T-Lymphocytes*/immunology
T-Lymphocytes*/metabolism
T-Lymphocytes*/transplantation
Humans ; CARD Signaling Adaptor Proteins/genetics ; CARD Signaling Adaptor Proteins/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cytokines/biosynthesis ; Cytokines/immunology ; Cytokines/metabolism ; Guanylate Cyclase/genetics ; Guanylate Cyclase/metabolism ; Phosphatidylinositol 3-Kinases ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques.
Autorzy:
McMahan K; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Wegmann F; Janssen Vaccines and Prevention, Leiden, Netherlands.
Aid M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Sciacca M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Liu J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Hachmann NP; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Miller J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jacob-Dolan C; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Powers O; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Hope D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Wu C; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Pereira J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Murdza T; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Mazurek CR; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Hoyt A; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Boon ACM; Washington University School of Medicine, St Louis, MO, USA.
Davis-Gardner M; Emory School of Medicine, Atlanta, GA, USA.
Suthar MS; Emory School of Medicine, Atlanta, GA, USA.
Martinot AJ; Tufts University Cummings School of Veterinary Medicine, Grafton, MA, USA.
Boursiquot M; Bioqual, Rockville, MD, USA.
Cook A; Bioqual, Rockville, MD, USA.
Pessaint L; Bioqual, Rockville, MD, USA.
Lewis MG; Bioqual, Rockville, MD, USA.
Andersen H; Bioqual, Rockville, MD, USA.
Tolboom J; Janssen Vaccines and Prevention, Leiden, Netherlands.
Serroyen J; Janssen Vaccines and Prevention, Leiden, Netherlands.
Solforosi L; Janssen Vaccines and Prevention, Leiden, Netherlands.
Costes LMM; Janssen Vaccines and Prevention, Leiden, Netherlands.
Zahn RC; Janssen Vaccines and Prevention, Leiden, Netherlands.
Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA. .; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7998), pp. 385-391. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
COVID-19*/immunology
COVID-19*/prevention & control
COVID-19*/virology
COVID-19 Vaccines*/administration & dosage
COVID-19 Vaccines*/immunology
Immunity, Mucosal*/immunology
Immunization, Secondary*/methods
Macaca mulatta*/immunology
Macaca mulatta*/virology
SARS-CoV-2*/classification
SARS-CoV-2*/immunology
Animals ; Humans ; Administration, Intranasal ; Antibodies, Neutralizing/biosynthesis ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/biosynthesis ; Antibodies, Viral/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cytokines/immunology ; Immunoglobulin A/immunology ; Immunoglobulin G/immunology ; Injections, Intramuscular ; Killer Cells, Natural/immunology ; Lung/immunology ; mRNA Vaccines/administration & dosage ; mRNA Vaccines/immunology ; Trachea/immunology ; Trachea/virology
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Autoreactive T cells target peripheral nerves in Guillain-Barré syndrome.
Autorzy:
Súkeníková L; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Mallone A; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Schreiner B; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Ripellino P; Department of Neurology, Neurocenter of Southern Switzerland EOC, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.
Nilsson J; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Stoffel M; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.; Medical Faculty, University of Zurich, Zurich, Switzerland.
Ulbrich SE; Animal Physiology, Institute of Agricultural Sciences, ETH Zurich, Zurich, Switzerland.
Sallusto F; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.; Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
Latorre D; Institute of Microbiology, ETH Zurich, Zurich, Switzerland. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7997), pp. 160-168. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*
CD8-Positive T-Lymphocytes*/immunology
CD8-Positive T-Lymphocytes*/pathology
Guillain-Barre Syndrome*/blood
Guillain-Barre Syndrome*/cerebrospinal fluid
Guillain-Barre Syndrome*/etiology
Guillain-Barre Syndrome*/immunology
Peripheral Nerves*/immunology
Peripheral Nerves*/pathology
Peripheral Nervous System Diseases*/complications
Peripheral Nervous System Diseases*/immunology
Peripheral Nervous System Diseases*/pathology
Th1 Cells*/immunology
Th1 Cells*/pathology
Humans ; Biopsy ; HLA-DR Antigens/immunology ; Immunodominant Epitopes/immunology ; Myelin Sheath/immunology ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/pathology ; Immunologic Memory
Czasopismo naukowe
Tytuł:
Prevention of respiratory virus transmission by resident memory CD8 T cells.
Autorzy:
Uddbäck I; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Michalets SE; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Saha A; Department of Biology, Emory University, Atlanta, GA, USA.
Mattingly C; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Kost KN; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Williams ME; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Lawrence LA; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Hicks SL; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Lowen AC; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Ahmed H; Department of Biology, Emory University, Atlanta, GA, USA.
Thomsen AR; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Russell CJ; Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN, USA.
Scharer CD; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Boss JM; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Koelle K; Department of Biology, Emory University, Atlanta, GA, USA.
Antia R; Department of Biology, Emory University, Atlanta, GA, USA.
Christensen JP; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Kohlmeier JE; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7998), pp. 392-400. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/immunology
Immunologic Memory*/immunology
Memory T Cells*/immunology
Paramyxoviridae Infections*/immunology
Paramyxoviridae Infections*/prevention & control
Paramyxoviridae Infections*/transmission
Paramyxoviridae Infections*/virology
Respiratory System*/cytology
Respiratory System*/immunology
Respiratory System*/virology
Animals ; Mice ; Disease Models, Animal ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Immunity, Herd/immunology ; Interferon-gamma/immunology ; Paramyxoviridae/immunology ; Paramyxoviridae/physiology ; Transcription, Genetic ; Humans
Czasopismo naukowe
Tytuł:
The glycoimmune checkpoint receptor Siglec-7 interacts with T-cell ligands and regulates T-cell activation.
Autorzy:
Stewart N; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Daly J; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Drummond-Guy O; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Krishnamoorthy V; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Stark JC; Department of Chemistry & Sarafan ChEM-H, Stanford University, Stanford, California, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Boston, Massachusetts, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Boston, Massachusetts, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Boston, Massachusetts, USA.
Riley NM; Department of Chemistry & Sarafan ChEM-H, Stanford University, Stanford, California, USA; Department of Chemistry, University of Washington, Seattle, Washington, USA.
Williams KC; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Bertozzi CR; Department of Chemistry & Sarafan ChEM-H, Stanford University, Stanford, California, USA; Howard Hughes Medical Institute, Stanford, California, USA.
Wisnovsky S; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Feb; Vol. 300 (2), pp. 105579. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Differentiation, Myelomonocytic*/genetics
Antigens, Differentiation, Myelomonocytic*/immunology
Ligands*
Lymphocyte Activation*/genetics
Lymphocyte Activation*/immunology
T-Lymphocytes*/immunology
Cell Polarity/genetics ; Gene Expression Regulation/genetics ; Gene Expression Regulation/immunology ; N-Acetylglucosaminyltransferases/genetics ; N-Acetylglucosaminyltransferases/metabolism ; Polysaccharides/metabolism ; Protein Binding ; Signal Transduction ; Humans
Czasopismo naukowe
Tytuł:
Interleukin-7 potentiates MAPK10-elicited host-protective vaccine against Leishmania donovani.
Autorzy:
Kumar S; National Centre for Cell Science, Ganeshkhind, Pune 411007. India.
Bodhale N; National Centre for Cell Science, Ganeshkhind, Pune 411007. India.
Patra SK; National Centre for Cell Science, Ganeshkhind, Pune 411007. India.
Sarode A; National Centre for Cell Science, Ganeshkhind, Pune 411007. India.
Zhao L; Ling Zhao, Huazhong Agricultural University, Wuhan 430070, China.
Sarkar A; Trident Academy of Creative Technology, Bhubaneswar 751024. India.
Saha B; National Centre for Cell Science, Ganeshkhind, Pune 411007. India; Trident Academy of Creative Technology, Bhubaneswar 751024. India. Electronic address: .
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Źródło:
Cytokine [Cytokine] 2024 Feb; Vol. 174, pp. 156475. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Leishmaniasis Vaccines*/immunology
Leishmania donovani*/immunology
Leishmaniasis, Visceral*/prevention & control
Mitogen-Activated Protein Kinase 10*/immunology
Interleukin-7*/administration & dosage
Adjuvants, Vaccine*
Animals ; Mice ; Mice, Inbred BALB C ; Receptors, Interleukin-7/metabolism ; Interferon-gamma/metabolism ; Th1 Cells/immunology ; Macrophages/immunology ; Macrophages/parasitology ; Leishmania major/immunology ; Coculture Techniques ; Memory T Cells/immunology ; Spleen/parasitology ; Liver/parasitology ; Antigen Presentation
Czasopismo naukowe
Tytuł:
Sleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression.
Autorzy:
Xing C; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China. Electronic address: .
Zhai B; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China; Department of Geriatric Hematology, Nanlou Division, Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases, Beijing, 100853, China.
Zhang Y; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Fang Y; Department of Rheumatology, First Hospital of Jilin University, Changchun, 130021, China.
Zhang M; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Zhang C; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China; Laboratory of Cellular and Molecular Immunology, School of Medicine, Henan University, Kaifeng, 475004, China.
Wang W; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China; School of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, 154007, China.
Ding M; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Huang X; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Shen B; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
Wang R; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, 100069, China. Electronic address: renxi_.
Song L; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jan 08; Vol. 691, pp. 149326. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Sleep Deprivation*/genetics
Sleep Deprivation*/immunology
Immunoglobulin G*/genetics
Immunoglobulin G*/immunology
ARNTL Transcription Factors*/genetics
ARNTL Transcription Factors*/immunology
CLOCK Proteins*/genetics
CLOCK Proteins*/immunology
Antibody Formation*/drug effects
Antibody Formation*/genetics
Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Rats, Sprague-Dawley ; Mice, Inbred C57BL ; B-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/immunology ; Stress, Physiological/immunology ; Animals ; Mice ; Rats ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Spatial IMA1 regulation restricts root iron acquisition on MAMP perception.
Autorzy:
Cao M; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Platre MP; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Tsai HH; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.
Zhang L; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Nobori T; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.; Genomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA, USA.
Armengot L; Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, Spain.; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona, Barcelona, Spain.
Chen Y; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
He W; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Brent L; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Coll NS; Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, Spain.; Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, Spain.
Ecker JR; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.; Genomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA, USA.
Geldner N; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.
Busch W; Plant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. .; Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. .
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Źródło:
Nature [Nature] 2024 Jan; Vol. 625 (7996), pp. 750-759. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis*/immunology
Arabidopsis*/metabolism
Arabidopsis*/microbiology
Arabidopsis Proteins*/metabolism
Bacteria*/immunology
Bacteria*/metabolism
Intracellular Signaling Peptides and Proteins*/metabolism
Iron*/metabolism
Plant Roots*/immunology
Plant Roots*/metabolism
Plant Roots*/microbiology
Pathogen-Associated Molecular Pattern Molecules*/immunology
Pathogen-Associated Molecular Pattern Molecules*/metabolism
Flagellin/immunology ; Gene Expression Regulation, Plant ; Plant Immunity ; Plant Shoots/immunology ; Plant Shoots/metabolism ; Plant Shoots/microbiology ; Rhizosphere
Czasopismo naukowe
Tytuł:
Swarna Bhasma Induces Antigen-Presenting Abilities of Macrophages and Helps Antigen Experienced CD4 T Cells to Acquire Th1 Phenotypes Against Leishmania donovani Antigens.
Autorzy:
Saini S; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.
Anand A; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.
Singh A; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.
Mahapatra B; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.
Sirohi S; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.
Singh S; Centre of Experimental Medicine and Surgery, Institute of Medical Science, Banaras Hindu University, Varanasi, 221 005, India.
Singh RK; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India. rakesh_.
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Źródło:
Biological trace element research [Biol Trace Elem Res] 2024 Jan; Vol. 202 (1), pp. 210-220. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Gold*/administration & dosage
Gold*/pharmacology
Latex*/administration & dosage
Latex*/pharmacology
Calotropis*
Medicine, Ayurvedic*
Macrophages*/drug effects
Macrophages*/immunology
CD4-Positive T-Lymphocytes*/immunology
Leishmania donovani*/drug effects
Leishmania donovani*/growth & development
Leishmania donovani*/immunology
Antigens, Protozoan*/immunology
Antigen Presentation*
Th1 Cells*/immunology
Arsenic ; Drug Combinations ; Lead ; Phagocytes/drug effects ; Phagocytes/immunology ; Leishmaniasis/immunology ; Leishmaniasis/parasitology ; Animals ; Mice ; RAW 264.7 Cells ; Female ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł:
The PfRCR complex bridges malaria parasite and erythrocyte during invasion.
Autorzy:
Farrell B; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Alam N; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Hart MN; The Royal Veterinary College, Hatfield, UK.
Jamwal A; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Ragotte RJ; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Walters-Morgan H; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Draper SJ; Department of Biochemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.
Knuepfer E; The Royal Veterinary College, Hatfield, UK.
Higgins MK; Department of Biochemistry, University of Oxford, Oxford, UK. .; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK. .
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Źródło:
Nature [Nature] 2024 Jan; Vol. 625 (7995), pp. 578-584. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Erythrocytes*/metabolism
Erythrocytes*/parasitology
Malaria, Falciparum*/immunology
Malaria, Falciparum*/metabolism
Malaria, Falciparum*/parasitology
Malaria, Falciparum*/pathology
Multiprotein Complexes*/chemistry
Multiprotein Complexes*/immunology
Multiprotein Complexes*/metabolism
Multiprotein Complexes*/ultrastructure
Parasites*/metabolism
Parasites*/pathogenicity
Plasmodium falciparum*/metabolism
Plasmodium falciparum*/pathogenicity
Protozoan Proteins*/chemistry
Protozoan Proteins*/immunology
Protozoan Proteins*/metabolism
Protozoan Proteins*/ultrastructure
Animals ; Humans ; Antibodies, Neutralizing/immunology ; Antigens, Protozoan/chemistry ; Antigens, Protozoan/immunology ; Cryoelectron Microscopy ; Disulfides/chemistry ; Disulfides/metabolism ; Malaria Vaccines/immunology ; Merozoites/metabolism
Czasopismo naukowe
Tytuł:
Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides.
Autorzy:
Huang D; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhu X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Ye S; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhang J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Liao J; Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhang N; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zeng X; Program of Molecular Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Wang J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Yang B; Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhang Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Lao L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Chen J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Xin M; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Nie Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Saw PE; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Su S; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .; Department of Immunology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China. .; Department of Infectious Diseases, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. .; Biotherapy Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .
Song E; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .
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Źródło:
Nature [Nature] 2024 Jan; Vol. 625 (7995), pp. 593-602. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/immunology
Breast Neoplasms*/mortality
Breast Neoplasms*/pathology
Melanoma*/genetics
Melanoma*/immunology
Melanoma*/mortality
Melanoma*/pathology
Peptides*/genetics
Peptides*/immunology
Protein Biosynthesis*
RNA, Circular*/genetics
RNA, Circular*/metabolism
Animals ; Female ; Humans ; Mice ; Antigens, Neoplasm/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Histocompatibility Antigens Class I/immunology ; Histocompatibility Antigens Class II/immunology ; Mass Spectrometry ; Ribosome Profiling ; Survival Analysis
Czasopismo naukowe
Tytuł:
Brazil's record dengue surge: why a vaccine campaign is unlikely to stop it.
Autorzy:
Lenharo M
Pokaż więcej
Źródło:
Nature [Nature] 2024 Mar; Vol. 627 (8003), pp. 250-251.
Typ publikacji:
Wiadomości
MeSH Terms:
Dengue*/epidemiology
Dengue*/immunology
Dengue*/prevention & control
Dengue*/virology
Dengue Vaccines*/administration & dosage
Dengue Vaccines*/immunology
Dengue Vaccines*/supply & distribution
Immunization Programs*
Humans ; Brazil/epidemiology ; Dengue Virus/immunology
Periodyk
Tytuł:
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants.
Autorzy:
Materna M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Delmonte OM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Bosticardo M; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Momenilandi M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Conrey PE; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Charmeteau-De Muylder B; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.
Bravetti C; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.; Sorbonne University, Paris Cancer Institute CURAMUS, INSERM U1138, Paris, France.
Bellworthy R; Deptartment of Human Genetics, Dahdaleh Institute of Genomic Medicine, McGill University, Montreal, QC, Canada.
Cederholm A; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Staels F; Allergy and Clinical Immunology Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Ganoza CA; Centogene GmbH, Rostock, Germany.
Darko S; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sayed S; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Le Floc'h C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Ogishi M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Rinchai D; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Guenoun A; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Bolze A; Helix, San Mateo, CA, USA.
Khan T; Department of Human Immunology, Sidra Medicine, Doha, Qatar.; The Jackson Laboratory, Farmington, CT, USA.
Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Krüger R; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Völler M; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Palterer B; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sadeghi-Shabestari M; Immunology Research Center, TB and Lung Disease Research Center, Mardaniazar Children Hospital, Tabriz University of Medical Science, Tabriz, Iran.
Langlois de Septenville A; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.
Schramm CA; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Shah S; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Tello-Cajiao JJ; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Pala F; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Amini K; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Campos JS; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lima NS; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Eriksson D; Department of Immunology, Genetics and Pathology, Uppsala University and University Hospital, Section of Clinical Genetics, Uppsala, Sweden.
Lévy R; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
Seeleuthner Y; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Jyonouchi S; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ata M; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Al Ali F; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Deswarte C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Pereira A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Mégret J; Cytometry Core Facility, SFR Necker, INSERM US24-CNRS UAR3633, Paris, France.
Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
Berteloot L; Department of Pediatric Radiology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France.
Dussiot M; Imagine Institute, University of Paris-Cité, Paris, France.; Laboratory of Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, INSERM UMR 1163, Paris, France.
Vladikine N; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Cardenas PP; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain.
Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Alqahtani M; Department of Translational Genomics, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Hasan A; Department of Translational Research, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Thanaraj TA; Department of Genetics and Bioinformatics, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Al Qureshah F; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Sabato V; Department of Immunology, Allergology and Rheumatology, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Alyanakian MA; Immunology Laboratory, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Leruez-Ville M; Necker Hospital for Sick Children, AP-HP, Paris, France.
Rozenberg F; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.; Virology, Cochin Hospital, AP-HP, APHP-CUP, Paris, France.
Haddad E; Department of Pediatrics, Department of Microbiology, Immunology and Infectious Diseases, University of Montreal, CHU Sainte-Justine, Montreal, QC, Canada.
Regueiro JR; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain.
Toribio ML; Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Kelsen JR; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Salehi M; Cellular, Molecular and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Genetics and Molecular Biology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Nasiri S; Department of Pediatric Neurology, Children's Medical Center of Abuzar, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Torabizadeh M; Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Rokni-Zadeh H; Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences (ZUMS), Zanjan, Iran.
Changi-Ashtiani M; School of Mathematics, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
Vatandoost N; Department of Genetics and Molecular Biology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.; Pediatric Inherited Diseases Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Moravej H; Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Akrami SM; Medical Genetics Poursina St., Genetic Department, Medical Faculty, Tehran University of Medical Sciences, Tehran, Iran.; Dr. Shahrooei Laboratory, Tehran, Iran.
Mazloomrezaei M; Dr. Shahrooei Laboratory, Tehran, Iran.
Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Meyts I; Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.; Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Toyofuku E; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.
Nishimura M; Department of Pediatrics, NHO Kumamoto Medical Center, Kumamoto, Japan.
Moriya K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Mizukami T; Department of Pediatrics, NHO Kumamoto Medical Center, Kumamoto, Japan.
Imai K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Abel L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Malissen B; Immunology Center of Marseille-Luminy, Aix Marseille University, Inserm, CNRS, Marseille, France.; Immunophenomics Center (CIPHE), Aix Marseille Université, Inserm, CNRS, Marseille, France.
Al-Mulla F; Department of Genetics and Bioinformatics, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Alkuraya FS; Department of Translational Genomics, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Parvaneh N; Division of Allergy and Clinical Immunology, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.
von Bernuth H; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.; Labor Berlin GmbH, Department of Immunology, Berlin, Germany.
Beetz C; Centogene GmbH, Rostock, Germany.
Davi F; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.; Sorbonne University, Paris Cancer Institute CURAMUS, INSERM U1138, Paris, France.
Douek DC; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Cheynier R; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.
Langlais D; Deptartment of Human Genetics, Dahdaleh Institute of Genomic Medicine, McGill University, Montreal, QC, Canada.
Landegren N; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institute, Stockholm, Sweden.
Marr N; Department of Human Immunology, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
Morio T; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.
Shahrooei M; Dr. Shahrooei Laboratory, Tehran, Iran.; Clinical and Diagnostic Immunology, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.
Schrijvers R; Allergy and Clinical Immunology Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Henrickson SE; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Luche H; Immunophenomics Center (CIPHE), Aix Marseille Université, Inserm, CNRS, Marseille, France.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Béziat V; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar; Vol. 383 (6686), pp. eadh4059. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*/genetics
Intraepithelial Lymphocytes*/immunology
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Membrane Glycoproteins*/genetics
Humans ; Cell Differentiation ; Homozygote ; Loss of Function Mutation ; Lymphocyte Count ; Alleles ; Infections/immunology ; Lymphoproliferative Disorders/immunology ; Pedigree ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over
Czasopismo naukowe
Tytuł:
Failure to launch? Or a 30-year career detour? A users' manual for supporting second-career scientists in your immunology lab.
Autorzy:
Nazzaro MN; Fred Hutch Cancer Center, Seattle, WA, USA.
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Źródło:
Immunology and cell biology [Immunol Cell Biol] 2024 Mar; Vol. 102 (3), pp. 156-159. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
Career Choice*
Allergy and Immunology*
Humans ; Research Personnel
Czasopismo naukowe
Tytuł:
An immunogenetic basis for lung cancer risk.
Autorzy:
Krishna C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Tervi A; Institute for Molecular Medicine, Finland (FIMM), HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Saffern M; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Wilson EA; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Yoo SK; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mars N; Institute for Molecular Medicine, Finland (FIMM), HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Roudko V; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cho BA; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jones SE; Institute for Molecular Medicine, Finland (FIMM), HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Vaninov N; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Selvan ME; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Gümüş ZH; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Lenz TL; Research Unit for Evolutionary Immunogenomics, Department of Biology, Universität Hamburg, 20146 Hamburg, Germany.
Merad M; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Boffetta P; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.; Stony Brook Cancer Center, Stony Brook University, New York, NY 11794, USA.
Martínez-Jiménez F; Vall d'Hebron Institute of Oncology, Barcelona 08035, Spain.; Hartwig Medical Foundation, Amsterdam 1098 XH, the Netherlands.
Ollila HM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Institute for Molecular Medicine, Finland (FIMM), HiLIFE, University of Helsinki, Helsinki 00290, Finland.; Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Samstein RM; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Radiation Oncology, Mount Sinai Hospital, New York, NY 10029, USA.
Chowell D; The Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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Corporate Authors:
FinnGen§
Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 23; Vol. 383 (6685), pp. eadi3808. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Histocompatibility Antigens Class II*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/immunology
Loss of Heterozygosity*
Immunologic Surveillance*/genetics
Genetic Predisposition to Disease*
Humans ; Macrophages, Alveolar/immunology ; Risk Factors ; Smoking/immunology ; Middle Aged ; Aged ; Aged, 80 and over ; Chromosome Mapping ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma.
Autorzy:
Ziman B; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA.; Department of Otolaryngology Head and Neck, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA.
Yang Q; Samuel Oschin Comprehensive Cancer Institute, Department of Medicine, Cedars-Sinai Medical Center, 127S. San Vicente Blvd, Los Angeles, CA, 90048, USA.
Zheng Y; Samuel Oschin Comprehensive Cancer Institute, Department of Medicine, Cedars-Sinai Medical Center, 127S. San Vicente Blvd, Los Angeles, CA, 90048, USA.
Sheth M; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA.
Nam C; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA.
Zhao H; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA.
Zhang L; Samuel Oschin Comprehensive Cancer Institute, Department of Medicine, Cedars-Sinai Medical Center, 127S. San Vicente Blvd, Los Angeles, CA, 90048, USA.
Hu B; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA.
Bhowmick NA; Samuel Oschin Comprehensive Cancer Institute, Department of Medicine, Cedars-Sinai Medical Center, 127S. San Vicente Blvd, Los Angeles, CA, 90048, USA.
Sinha UK; Department of Otolaryngology Head and Neck, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA. .
Lin DC; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, 2250 Alcazar St, Los Angeles, CA, 90089, USA. .; Department of Otolaryngology Head and Neck, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA. .
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Źródło:
Cell death & disease [Cell Death Dis] 2024 Feb 19; Vol. 15 (2), pp. 152. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/genetics
Adenocarcinoma*/immunology
Adenocarcinoma*/pathology
CD8-Positive T-Lymphocytes*/metabolism
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/immunology
Forkhead Box Protein M1*/genetics
Forkhead Box Protein M1*/metabolism
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Epigenomics ; Gene Expression Regulation, Neoplastic ; Immunity ; Tumor Microenvironment/immunology
SCR Disease Name:
Adenocarcinoma Of Esophagus
Czasopismo naukowe

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