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Wyszukujesz frazę ""Immunology"" wg kryterium: Temat


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Tytuł :
Highlights of the 33rd annual scientific meeting of the Association of Medical Laboratory Immunologists (AMLI).
Autorzy :
Knight V; Department of Pediatrics and Children's Hospital, University of Colorado School of Medicine, Aurora, CO, United States of America. Electronic address: .
Askar MZ; Baylor University Medical Center, Dallas, TX, United States of America.
Ntrivalas E; Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.
Nandiwada SL; Baylor College of Medicine and Texas Children's Hospital, Houston, TX, United States of America.
Peterson LK; ARUP Institute for Clinical and Experimental Pathology and Department of Pathology, University of Utah Health, Salt Lake City, UT, United States of America.
Tebo AE; ARUP Institute for Clinical and Experimental Pathology and Department of Pathology, University of Utah Health, Salt Lake City, UT, United States of America.
Kadkhoda K; Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, United States of America.
Schmitz JL; Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America.
Naides SJ; Euroimmun US Inc., Mountain Lakes, NJ, United States of America.
Snyder MR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America.
Sadighi Akha AA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of America. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 May; Vol. 492, pp. 112994. Date of Electronic Publication: 2021 Feb 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Allergy and Immunology*
Societies, Medical*
COVID-19/*immunology
Immunotherapy/*methods
SARS-CoV-2/*physiology
Algorithms ; Animals ; Group Processes ; Histocompatibility Testing ; Host-Pathogen Interactions ; Humans ; Laboratories ; Pandemics ; SARS-CoV-2/chemistry ; Transplantation Immunology ; Virtual Reality
Czasopismo naukowe
Tytuł :
Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients.
Autorzy :
Sattler A; Department for General and Visceral Surgery and.
Schrezenmeier E; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Weber UA; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Potekhin A; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; MVZ Diaverum Neubrandenburg, Neubrandenburg, Germany.
Bachmann F; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Straub-Hohenbleicher H; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Budde K; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Storz E; Department for General and Visceral Surgery and.
Proß V; Department for General and Visceral Surgery and.
Bergmann Y; Department for General and Visceral Surgery and.
Thole LM; Department for General and Visceral Surgery and.
Tizian C; Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and BIH, Berlin, Germany.
Hölsken O; Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and BIH, Berlin, Germany.; Heidelberg Bioscience International Graduate School, Heidelberg University, Heidelberg, Germany.
Diefenbach A; Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and BIH, Berlin, Germany.
Schrezenmeier H; Department of Transfusion Medicine and Institute for Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Transfusion Service, Baden-Württemberg-Hessen and University Hospital Ulm, Ulm University, Ulm, Germany.
Jahrsdörfer B; Department of Transfusion Medicine and Institute for Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Transfusion Service, Baden-Württemberg-Hessen and University Hospital Ulm, Ulm University, Ulm, Germany.
Zemojtel T; Genomics Core Facility.
Jechow K; Center for Digital Health, and.
Conrad C; Center for Digital Health, and.
Lukassen S; Center for Digital Health, and.
Stauch D; HLA Laboratory, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and BIH, Berlin, Germany.
Lachmann N; HLA Laboratory, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and BIH, Berlin, Germany.
Choi M; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Halleck F; Department of Nephrology and Intensive Care, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Kotsch K; Department for General and Visceral Surgery and.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Jul 15; Vol. 131 (14).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*/immunology
COVID-19/*immunology
COVID-19/*prevention & control
COVID-19 Vaccines/*administration & dosage
Kidney Transplantation/*adverse effects
Adult ; Aged ; Antibodies, Viral/biosynthesis ; COVID-19 Vaccines/immunology ; Case-Control Studies ; Cohort Studies ; Cytokines/immunology ; Female ; Humans ; Immunity, Cellular ; Immunity, Humoral ; Immunization, Secondary ; Immunoglobulin A/biosynthesis ; Immunoglobulin G/biosynthesis ; Immunologic Memory ; Immunosuppressive Agents/adverse effects ; Lymphocyte Activation ; Male ; Middle Aged ; Monitoring, Immunologic ; Renal Dialysis/adverse effects ; Spike Glycoprotein, Coronavirus/immunology ; T-Lymphocytes/immunology ; Transplantation Immunology
Czasopismo naukowe
Tytuł :
Dendritic Cells: Versatile Players in Renal Transplantation.
Autorzy :
Lin J; Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Key Laboratory of Kidney Disease Prevention and Control Technology, National Key Clinical Department of Kidney Disease, Institute of Nephrology, Zhejiang University, Hangzhou, China.; The Third Grade Laboratory under the National State, Administration of Traditional Chinese Medicine, Hangzhou, China.
Wang H; Xiangya School of Medicine, Central South University, Changsha, China.
Liu C; Xiangya School of Medicine, Central South University, Changsha, China.
Cheng A; Xiangya School of Medicine, Central South University, Changsha, China.
Deng Q; Xiangya School of Medicine, Central South University, Changsha, China.
Zhu H; Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Chen J; Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Key Laboratory of Kidney Disease Prevention and Control Technology, National Key Clinical Department of Kidney Disease, Institute of Nephrology, Zhejiang University, Hangzhou, China.; The Third Grade Laboratory under the National State, Administration of Traditional Chinese Medicine, Hangzhou, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 19; Vol. 12, pp. 654540. Date of Electronic Publication: 2021 May 19 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Kidney Transplantation*
Transplantation Immunology*
Dendritic Cells/*immunology
Dendritic Cells/*metabolism
Acute Disease ; Allografts ; Animals ; Chronic Disease ; Graft Rejection/immunology ; Graft Survival/immunology ; Humans ; Immune Tolerance ; Immunomodulation ; Immunotherapy ; Reperfusion Injury/etiology ; Reperfusion Injury/metabolism
Czasopismo naukowe
Tytuł :
Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice.
Autorzy :
Silvas JA; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Vasquez DM; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Park JG; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Chiem K; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Allué-Guardia A; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Garcia-Vilanova A; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Platt RN; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Kehrer T; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Cupic A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Gonzalez-Reiche AS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Bakel HV; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Anderson T; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Torrelles JB; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Ye C; Texas Biomedical Research Institute, San Antonio, Texas, USA.
Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, Texas, USA.
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Źródło :
Journal of virology [J Virol] 2021 Aug 10; Vol. 95 (17), pp. e0040221. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Viral Proteins*/genetics
Viral Proteins*/immunology
Angiotensin-Converting Enzyme 2/*immunology
Open Reading Frames/*immunology
A549 Cells ; Angiotensin-Converting Enzyme 2/genetics ; Animals ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/immunology ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Mice ; Mice, Transgenic ; Vaccines, Attenuated/genetics ; Vaccines, Attenuated/immunology ; Vero Cells
Czasopismo naukowe
Tytuł :
The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?
Autorzy :
Morris G; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia.
Bortolasci CC; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Deakin University, Centre for Molecular and Medical Research, School of Medicine, Geelong, Australia.
Puri BK; C.A.R., Cambridge, UK.
Marx W; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia.
O'Neil A; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Melbourne School of Population and Global Health, Melbourne, Australi.
Athan E; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Barwon Health, Geelong, Australia.
Walder K; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Deakin University, Centre for Molecular and Medical Research, School of Medicine, Geelong, Australia.
Berk M; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry, The University of Melbourne, Melbourne, Australia.
Olive L; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Deakin University, School of Psychology, Geelong, Australia.
Carvalho AF; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, University of Toronto, Toronto, Canada, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
Maes M; Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, King Chulalongkorn University Hospital, Bangkok, Thailand; Department of Psychiatry, Medical University of Plovdiv, Plovdiv, Bulgaria. Electronic address: .
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Źródło :
Cytokine [Cytokine] 2021 Aug; Vol. 144, pp. 155593. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19*/drug therapy
COVID-19*/immunology
COVID-19*/mortality
COVID-19*/pathology
Cytokine Release Syndrome*/drug therapy
Cytokine Release Syndrome*/immunology
Cytokine Release Syndrome*/mortality
Cytokine Release Syndrome*/pathology
Anti-Inflammatory Agents/*therapeutic use
Antiviral Agents/*therapeutic use
Influenza A Virus, H1N1 Subtype/*immunology
SARS-CoV-2/*immunology
Disease-Free Survival ; Humans ; Influenza, Human/drug therapy ; Influenza, Human/immunology ; Influenza, Human/mortality ; Influenza, Human/pathology ; Janus Kinases/antagonists & inhibitors ; Janus Kinases/metabolism ; Lymphocytes/immunology ; Lymphocytes/pathology ; Survival Rate
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Gut microbiota shape B cell in health and disease settings.
Autorzy :
Yu B; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wang L; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Endocrinology and Metabolism, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.; Biotherapy Research Center, Fudan University, Shanghai, China.
Chu Y; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Biotherapy Research Center, Fudan University, Shanghai, China.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2021 Aug; Vol. 110 (2), pp. 271-281. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Susceptibility*/immunology
Homeostasis*/immunology
B-Lymphocytes/*immunology
Gastrointestinal Microbiome/*immunology
Animals ; B-Lymphocytes/metabolism ; Dysbiosis/immunology ; Humans ; Lymphocyte Activation/genetics ; Lymphocyte Activation/immunology
Czasopismo naukowe
Tytuł :
Dietary supplementation of fermented lemon peel enhances lysozyme activity and susceptibility to Photobacterium damselae for orange-spotted grouper, Epinephelus coioides.
Autorzy :
Zhuo LC; Department of Aquaculture National Pingtung University of Science and Technology, No. 1 Shuefu Road, Neipu, Pingtung, 912, Taiwan, ROC.
Chen CF; Department of Aquaculture National Pingtung University of Science and Technology, No. 1 Shuefu Road, Neipu, Pingtung, 912, Taiwan, ROC; Symlong Bio-Tech Co., Ltd. 4 F, No. 8, Yuanxi 2nd Road, Changzhi, Pingtung, 908, Taiwan, ROC.
Lin YH; Department of Aquaculture National Pingtung University of Science and Technology, No. 1 Shuefu Road, Neipu, Pingtung, 912, Taiwan, ROC. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Oct; Vol. 117, pp. 248-252. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms :
Citrus*
Dietary Supplements*
Fruit*
Perciformes*/blood
Perciformes*/immunology
Perciformes*/microbiology
Photobacterium*
Fish Diseases/*immunology
Gram-Negative Bacterial Infections/*immunology
Muramidase/*immunology
Animals ; Disease Susceptibility ; Fermentation ; Gram-Negative Bacterial Infections/veterinary ; Liver/immunology ; Malondialdehyde/immunology ; Muramidase/blood
SCR Organism :
Photobacterium damselae
Czasopismo naukowe
Tytuł :
Epitope screening of the major capsid protein within grouper iridovirus of Taiwan and the immunoprotective effect with SWCNTs as the vaccine carrier.
Autorzy :
Zhang Z; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China.
Liu G; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China.
Liu J; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China.
Zhu B; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China.
Wang G; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China. Electronic address: .
Ling F; College of Animal Science and Technology, Northwest A & F University, Yangling, 712100, China. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Oct; Vol. 117, pp. 17-23. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Nanotubes, Carbon*/chemistry
Perciformes*/genetics
Perciformes*/immunology
Perciformes*/virology
Capsid Proteins/*immunology
DNA Virus Infections/*prevention & control
Drug Carriers/*administration & dosage
Epitopes/*immunology
Fish Diseases/*prevention & control
Iridoviridae/*immunology
Vaccines, Subunit/*administration & dosage
Viral Vaccines/*administration & dosage
Acid Phosphatase/immunology ; Alkaline Phosphatase/immunology ; Animals ; Antigens, Viral/immunology ; DNA Virus Infections/immunology ; Drug Carriers/chemistry ; Fish Diseases/immunology ; Gene Expression/drug effects ; Superoxide Dismutase/immunology ; Vaccines, Subunit/chemistry ; Viral Vaccines/chemistry
Czasopismo naukowe
Tytuł :
Impact of cinnamaldehyde on innate immunity and immune gene expression in Channa striatus against Aphanomyces invadans.
Autorzy :
Harikrishnan R; Department of Zoology, Pachaiyappa's College for Men, Kanchipuram, 631 501, Tamil Nadu, India. Electronic address: .
Devi G; Department of Zoology, Nehru Memorial College, Puthanampatti, 621 007, Tamil Nadu, India.
Balasundaram C; Department of Herbal and Environmental Science, Tamil University, Thanjavur, 613 005, Tamil Nadu, India.
Van Doan H; Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai, 50200, Thailand; Science and Technology Research Institute, Chiang Mai University, 239 Huay Keaw Rd., Suthep, Muang, Chiang Mai, 50200, Thailand. Electronic address: .
Jaturasitha S; Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai, 50200, Thailand; Science and Technology Research Institute, Chiang Mai University, 239 Huay Keaw Rd., Suthep, Muang, Chiang Mai, 50200, Thailand.
Saravanan K; Department of Zoology, Nehru Memorial College, Puthanampatti, 621 007, Tamil Nadu, India.
Ringø E; Norwegian College of Fishery Science, Faculty of Bioscience, Fisheries and Economics, UiT The Arctic University of Norway, Tromsø, Norway.
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Oct; Vol. 117, pp. 1-16. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Aphanomyces*
Fish Diseases*/genetics
Fish Diseases*/immunology
Infections*/genetics
Infections*/immunology
Infections*/veterinary
Acrolein/*analogs & derivatives
Fishes/*genetics
Fishes/*immunology
Gene Expression/*drug effects
Immunity, Innate/*drug effects
Acrolein/administration & dosage ; Animals ; Complement Activation/drug effects ; Diet ; Immunoglobulin M/immunology ; Leukocyte Count ; Muramidase/immunology ; Phagocytosis/drug effects ; Reactive Oxygen Species/immunology
Czasopismo naukowe
Tytuł :
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.
Autorzy :
Rosati M; Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Agarwal M; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Hu X; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Devasundaram S; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Stellas D; Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Chowdhury B; Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Bear J; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Burns R; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Donohue D; MS Applied Information and Management Sciences, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Pessaint L; BIOQUAL, Inc.; Rockville, Maryland, United States of America.
Andersen H; BIOQUAL, Inc.; Rockville, Maryland, United States of America.
Lewis MG; BIOQUAL, Inc.; Rockville, Maryland, United States of America.
Terpos E; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Dimopoulos MA; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Wlodawer A; Center for Structural Biology, National Cancer Institute, Frederick, Maryland, United States of America.
Mullins JI; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.; Department of Medicine, University of Washington, Seattle, Washington, United States of America.; Department of Global Health, University of Washington, Seattle, Washington, United States of America.
Venzon DJ; Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Pavlakis GN; Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
Felber BK; Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Sep 22; Vol. 17 (9), pp. e1009701. Date of Electronic Publication: 2021 Sep 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Macaca mulatta*
Vaccines, DNA*/administration & dosage
Vaccines, DNA*/immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*genetics
Spike Glycoprotein, Coronavirus/*immunology
Animals ; COVID-19/immunology ; COVID-19/therapy ; Cohort Studies ; DNA, Viral/immunology ; Disease Models, Animal ; Female ; Immunization, Passive ; Leukocytes, Mononuclear/immunology ; Mice ; RNA, Messenger/analysis ; SARS-CoV-2/genetics ; T-Lymphocytes/immunology
SCR Protocol :
COVID-19 serotherapy
Czasopismo naukowe
Tytuł :
Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients.
Autorzy :
Zhao XN; Center for Disease Control and Prevention of Chinese People's Liberation Army, Beijing, China.
You Y; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic, Australia.
Cui XM; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Gao HX; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Wang GL; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Zhang SB; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic, Australia.
Yao L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Duan LJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Zhu KL; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Wang YL; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Li L; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Lu JH; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Wang HB; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Fan JF; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Zheng HW; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China.
Dai EH; The Fifth Hospital of Shijiazhuang, Hebei Medical University, Shijiazhuang, China. .
Tian LY; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic, Australia. .; Department of Medical Biology, The University of Melbourne, Parkville, Vic, Australia. .
Ma MJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2021 Sep 16; Vol. 6 (1), pp. 342. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/genetics
COVID-19*/immunology
Single-Cell Analysis*
Carrier State/*immunology
Lymphocytes/*immunology
SARS-CoV-2/*immunology
Transcriptome/*immunology
Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Receptors, Antigen, B-Cell/genetics ; Receptors, Antigen, B-Cell/immunology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; SARS-CoV-2/genetics
Czasopismo naukowe
Tytuł :
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19.
Autorzy :
Ciaglia E; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.
Lopardo V; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.
Montella F; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.
Sellitto C; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Clinical Pharmacology and Pharmacogenetics Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
Manzo V; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Clinical Pharmacology and Pharmacogenetics Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
De Bellis E; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Clinical Pharmacology and Pharmacogenetics Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
Iannaccone T; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.
Franci G; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy.
Zannella C; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy.
Pagliano P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Infectious Diseases Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
Di Pietro P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.
Carrizzo A; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Isernia, Italy.
Vecchione C; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Isernia, Italy.
Conti V; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Clinical Pharmacology and Pharmacogenetics Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
Filippelli A; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Department of Clinical Pharmacology and Pharmacogenetics Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy.
Puca AA; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana,' University of Salerno, Baronissi, Italy.; Cardiovascular Research Unit, IRCCS MultiMedica, Milan, Italy.
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Źródło :
The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2021 Sep 13; Vol. 76 (10), pp. 1775-1783.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/epidemiology
COVID-19*/immunology
Intercellular Signaling Peptides and Proteins*/blood
Intercellular Signaling Peptides and Proteins*/immunology
Longevity/*immunology
Aged, 80 and over ; Biomarkers/blood ; Cell Line ; Cytokines/blood ; Cytotoxicity, Immunologic/drug effects ; Female ; Humans ; Immunologic Factors/immunology ; Immunologic Factors/pharmacology ; Inflammation/blood ; Inflammation/immunology ; Italy/epidemiology ; Male ; Prognosis ; Recombinant Proteins/immunology ; Recombinant Proteins/pharmacology ; SARS-CoV-2/immunology ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Single dose of BNT162b2 mRNA vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces neutralising antibody and polyfunctional T-cell responses in patients with chronic myeloid leukaemia.
Autorzy :
Harrington P; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Cancer and Pharmaceutical Science, King's College London, London, UK.
Doores KJ; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Radia D; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
O'Reilly A; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Lam HPJ; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Seow J; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Graham C; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Lechmere T; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
McLornan D; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Cancer and Pharmaceutical Science, King's College London, London, UK.
Dillon R; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; Department of Medicine and Molecular Genetics, King's College London, London, UK.
Shanmugharaj Y; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Espehana A; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Woodley C; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Saunders J; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Curto-Garcia N; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
O'Sullivan J; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Raj K; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Kordasti S; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Cancer and Pharmaceutical Science, King's College London, London, UK.
Malim MH; Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK.
Harrison C; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Cancer and Pharmaceutical Science, King's College London, London, UK.
de Lavallade H; Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.; School of Cancer and Pharmaceutical Science, King's College London, London, UK.; Department of Haematological Medicine, King's College London School of Medicine, London, UK.
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Źródło :
British journal of haematology [Br J Haematol] 2021 Sep; Vol. 194 (6), pp. 999-1006. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/immunology
COVID-19*/prevention & control
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
COVID-19 Vaccines/*administration & dosage
Hematologic Neoplasms/*immunology
Immunity, Cellular/*drug effects
Immunoglobulin G/*immunology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*immunology
SARS-CoV-2/*immunology
Adult ; Aged ; COVID-19 Vaccines/immunology ; Female ; Hematologic Neoplasms/drug therapy ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Male ; Middle Aged ; Protein Kinase Inhibitors/administration & dosage ; Spike Glycoprotein, Coronavirus/immunology
Czasopismo naukowe
Tytuł :
Reactive oxygen species-mediated immunity against bacterial infection in the gut of cat fleas (Ctenocephalides felis).
Autorzy :
Brown LD; Department of Biology, Georgia Southern University, 4324 Old Register Rd., Statesboro, GA, 30460, USA. Electronic address: .
Maness R; Department of Biology, Georgia Southern University, 4324 Old Register Rd., Statesboro, GA, 30460, USA.
Hall C; Department of Biology, Georgia Southern University, 4324 Old Register Rd., Statesboro, GA, 30460, USA.
Gibson JD; Department of Biology, Georgia Southern University, 4324 Old Register Rd., Statesboro, GA, 30460, USA.
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Źródło :
Insect biochemistry and molecular biology [Insect Biochem Mol Biol] 2021 Sep; Vol. 136, pp. 103620. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ctenocephalides*/immunology
Ctenocephalides*/metabolism
Ctenocephalides*/microbiology
Bacterial Infections/*immunology
Reactive Oxygen Species/*immunology
Animals ; Antioxidants/pharmacology ; Insect Vectors/immunology ; Insect Vectors/metabolism ; Insect Vectors/microbiology ; Intestines/microbiology ; Serratia/drug effects ; Serratia/immunology
Czasopismo naukowe
Tytuł :
Association of CXCR6 with COVID-19 severity: delineating the host genetic factors in transcriptomic regulation.
Autorzy :
Dai Y; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St. Suite 600, Houston, TX, 77030, USA.
Wang J; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA.
Jeong HH; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St. Suite 600, Houston, TX, 77030, USA.
Chen W; Immunobiology and Transplant Science Center, Department of Surgery, Houston Methodist Research Institute and Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, 77030, USA.; Department of Surgery, Weill Cornell Medicine, Cornell University, New York, NY, 10065, USA.
Jia P; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St. Suite 600, Houston, TX, 77030, USA.
Zhao Z; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St. Suite 600, Houston, TX, 77030, USA. .; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA. .; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA. .
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Źródło :
Human genetics [Hum Genet] 2021 Sep; Vol. 140 (9), pp. 1313-1328. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/genetics
COVID-19*/immunology
Receptors, CXCR6*/genetics
Receptors, CXCR6*/immunology
CD8-Positive T-Lymphocytes/*immunology
Immunologic Memory/*genetics
Lung/*immunology
Quantitative Trait Loci/*immunology
SARS-CoV-2/*immunology
Transcriptome/*immunology
Female ; Genome-Wide Association Study ; Humans ; Lung/virology ; Male ; Receptors, CCR/genetics ; Receptors, CCR/immunology ; Risk Factors ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Autorzy :
Starr TN; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Czudnochowski N; Vir Biotechnology, San Francisco, CA, USA.
Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Zatta F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Park YJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Addetia A; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Pinto D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Beltramello M; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Hernandez P; Vir Biotechnology, San Francisco, CA, USA.
Greaney AJ; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Marzi R; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Glass WG; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhang I; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
Dingens AS; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Wojcechowskyj JA; Vir Biotechnology, San Francisco, CA, USA.
De Marco A; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Rosen LE; Vir Biotechnology, San Francisco, CA, USA.
Zhou J; Vir Biotechnology, San Francisco, CA, USA.
Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA, USA.
Kaiser H; Vir Biotechnology, San Francisco, CA, USA.
Dillen JR; Vir Biotechnology, San Francisco, CA, USA.
Tucker H; Vir Biotechnology, San Francisco, CA, USA.
Bassi J; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Silacci-Fregni C; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Housley MP; Vir Biotechnology, San Francisco, CA, USA.
di Iulio J; Vir Biotechnology, San Francisco, CA, USA.
Lombardo G; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Agostini M; Vir Biotechnology, San Francisco, CA, USA.
Sprugasci N; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Culap K; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Jaconi S; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Meury M; Vir Biotechnology, San Francisco, CA, USA.
Dellota E Jr; Vir Biotechnology, San Francisco, CA, USA.
Abdelnabi R; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Foo SC; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Cameroni E; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Stumpf S; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Croll TI; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Cambridge, UK.
Nix JC; Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA, USA.
Piccoli L; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Benigni F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Neyts J; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Telenti A; Vir Biotechnology, San Francisco, CA, USA.
Lempp FA; Vir Biotechnology, San Francisco, CA, USA.
Pizzuto MS; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Chodera JD; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hebner CM; Vir Biotechnology, San Francisco, CA, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Corti D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. .
Bloom JD; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .
Snell G; Vir Biotechnology, San Francisco, CA, USA. .
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Źródło :
Nature [Nature] 2021 Sep; Vol. 597 (7874), pp. 97-102. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Immune Evasion*/genetics
Immune Evasion*/immunology
Broadly Neutralizing Antibodies/*immunology
COVID-19/*virology
Cross Reactions/*immunology
SARS-CoV-2/*classification
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*immunology
Adult ; Aged ; Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; Antibody Affinity ; Broadly Neutralizing Antibodies/chemistry ; COVID-19/drug therapy ; COVID-19/immunology ; COVID-19 Vaccines/chemistry ; COVID-19 Vaccines/immunology ; Cell Line ; Cricetinae ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/genetics ; Epitopes, B-Lymphocyte/immunology ; Female ; Humans ; Male ; Mesocricetus ; Middle Aged ; Models, Molecular ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Vaccinology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity.
Autorzy :
Sasaki M; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Toba S; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; Shionogi & Co., Ltd., Osaka, Japan.
Itakura Y; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Chambaro HM; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Kishimoto M; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Tabata K; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Intaruck K; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Uemura K; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; Shionogi & Co., Ltd., Osaka, Japan.; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Science, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Sanaki T; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; Shionogi & Co., Ltd., Osaka, Japan.
Sato A; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; Shionogi & Co., Ltd., Osaka, Japan.
Hall WW; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; National Virus Reference Laboratory, School of Medicine, University College of Dublin, Ireland.; Global Virus Network, Baltimore, Maryland, USA.
Orba Y; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Sawa H; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido Universitygrid.39158.36, Sapporo, Japan.; Global Virus Network, Baltimore, Maryland, USA.; One Health Research Center, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
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Źródło :
MBio [mBio] 2021 Aug 31; Vol. 12 (4), pp. e0141521. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/pathogenicity
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
COVID-19/*pathology
Spike Glycoprotein, Coronavirus/*genetics
Animals ; Cell Line ; Chlorocebus aethiops ; Cross Reactions/immunology ; Furin/metabolism ; Humans ; Vaccines, Attenuated/immunology ; Vero Cells ; Virulence/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma.
Autorzy :
Winter NA; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia.
Qin L; Department of Respiratory Medicine, Department of Pulmonary and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China.
Gibson PG; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Hunter Medical Research Institute, Newcastle, Australia.
McDonald VM; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Nursing and Midwifery, The University of Newcastle, Newcastle, Australia.
Baines KJ; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia.
Faulkner J; Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, Newcastle, Australia.
Evans TJ; Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, Newcastle, Australia.
Fricker M; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 428-438. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma*/immunology
Asthma*/pathology
Basophils*/immunology
Basophils*/pathology
Mast Cells*/immunology
Mast Cells*/pathology
Gene Expression Regulation/*immunology
Sputum/*immunology
Adult ; Aged ; Female ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Male ; Middle Aged ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Multidimensional study of the oral microbiome, metabolite, and immunologic environment in peanut allergy.
Autorzy :
Ho HE; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Chun Y; Icahn Institute for Data Science and Genome Technology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Jeong S; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.
Jumreornvong O; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.
Sicherer SH; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.
Bunyavanich S; Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Icahn Institute for Data Science and Genome Technology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 627-632.e3. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacteria*/classification
Bacteria*/immunology
Mouth*/immunology
Mouth*/microbiology
Peanut Hypersensitivity*/immunology
Peanut Hypersensitivity*/microbiology
Saliva*/immunology
Saliva*/microbiology
Microbiota/*immunology
Adolescent ; Child ; Cytokines/immunology ; Female ; Humans ; Male ; Th2 Cells/immunology
Czasopismo naukowe

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