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Tytuł :
Inhibition in growth and cardiotoxicity of tris (2-butoxyethyl) phosphate through down-regulating Wnt signaling pathway in early developmental stage of zebrafish (Danio rerio).
Autorzy :
Xiong H; College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.
Huang Y; College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.
Mao Y; College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.
Liu C; College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China; Key Lab of Freshwater Animal Breeding, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China.
Wang J; College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China; Key Lab of Freshwater Animal Breeding, Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111431. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Organophosphorus Compounds/*toxicity
Plasticizers/*toxicity
Water Pollutants, Chemical/*toxicity
Zebrafish/*physiology
Animals ; Cardiotoxicity ; Down-Regulation ; Embryo, Nonmammalian/drug effects ; Flame Retardants/metabolism ; In Situ Nick-End Labeling ; Larva/drug effects ; Organophosphates/metabolism ; Organophosphorus Compounds/metabolism ; Phosphates/metabolism ; Water Pollutants, Chemical/metabolism ; Wnt Signaling Pathway/physiology ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł :
miR-202-3p overexpression attenuates endometriosis-like lesions by modulating YAP-dependent transcription of S100A6 in murine models.
Autorzy :
Lan J; The Second Department of Gynecologic Oncology, Hunan Cancer Hospital (The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University), Changsha 410013, PR China.
Xie K; Department of Rehabilitation Medicine, Xiangya Hospital, Central South University, Changsha 410008, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118757. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing/*metabolism
Cell Cycle Proteins/*metabolism
Endometriosis/*metabolism
MicroRNAs/*metabolism
S100 Calcium Binding Protein A6/*metabolism
Animals ; Blotting, Western ; Disease Models, Animal ; Female ; Flow Cytometry ; Gene Expression Regulation ; In Situ Nick-End Labeling ; Mice ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: Through oxidative stress, apoptosis, and autophagy.
Autorzy :
Shah SWA; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China. Electronic address: .
Chen D; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China; College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China. Electronic address: .
Zhang J; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China. Electronic address: .
Liu Y; Heilongjiang Animal Husbandry Station, Harbin 150069, China. Electronic address: .
Ishfaq M; Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, 600 Chang jiang Road, Xiang Fang District, Harbin 150030, China. Electronic address: .
Tang Y; Electrical and Information Engineering College, Jilin Agricultural Science and Technology University, Jilin 132101, China. Electronic address: .
Teng X; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Dec 15; Vol. 206, pp. 111413. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Air Pollutants/*toxicity
Ammonia/*toxicity
Apoptosis/*drug effects
Chickens/*metabolism
Energy Metabolism/*drug effects
Mitochondrial Proteins/*metabolism
Oxidative Stress/*drug effects
Thymus Gland/*drug effects
Animals ; Antioxidants/metabolism ; Autophagy/drug effects ; In Situ Nick-End Labeling ; Mitochondrial Dynamics/drug effects ; Mitochondrial Proteins/genetics ; Thymus Gland/immunology ; Thymus Gland/metabolism ; Thymus Gland/pathology
Czasopismo naukowe
Tytuł :
MiR-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis.
Autorzy :
Liu W; Department of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Miao Y; Department of Medical Network Information Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhang L; Department of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Xu X; Department of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Luan Q; Department of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
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Źródło :
Bioengineered [Bioengineered] 2020 Dec; Vol. 11 (1), pp. 189-200.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*metabolism
Reperfusion Injury/*metabolism
Reperfusion Injury/*therapy
Animals ; Apoptosis/genetics ; Apoptosis/physiology ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Blotting, Western ; Brain/metabolism ; Flow Cytometry ; In Situ Nick-End Labeling ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Neurons/metabolism ; PC12 Cells ; Rats ; Reperfusion Injury/genetics
Czasopismo naukowe
Tytuł :
miR-22 protect PC12 from ischemia/reperfusion-induced injury by targeting p53 upregulated modulator of apoptosis (PUMA).
Autorzy :
Jiao H; Department of Anesthesia, Linyi Cancer Hospital, Linyi, Shandong, China.
Chen R; Department of Anesthesia, Linyi Cancer Hospital, Linyi, Shandong, China.
Jiang Z; External Abdominal Section, Linyi Cancer Hospital, Linyi, Shandong, China.
Zhang L; Department of Anesthesia, Linyi Cancer Hospital, Linyi, Shandong, China.
Wang H; Department of Anesthesia, Linyi Cancer Hospital, Linyi, Shandong, China.
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Źródło :
Bioengineered [Bioengineered] 2020 Dec; Vol. 11 (1), pp. 209-218.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis Regulatory Proteins/*metabolism
MicroRNAs/*metabolism
Myocardial Reperfusion Injury/*metabolism
Reperfusion Injury/*metabolism
Tumor Suppressor Protein p53/*metabolism
Animals ; Apoptosis ; Apoptosis Regulatory Proteins/genetics ; Blotting, Western ; In Situ Nick-End Labeling ; MicroRNAs/genetics ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/pathology ; PC12 Cells ; Rats ; Reperfusion Injury/genetics ; Reperfusion Injury/pathology ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203.
Autorzy :
Guo Y; Department of Pediatric Medicine, Linyi Central Hospital, Yishui, Shandong, China.
Zhu X; Department of Pediatric Medicine, Linyi Central Hospital, Yishui, Shandong, China.
Sun X; Department of Clinical Laboratory, Qingdao Women and Children's Hospital, Qingdao, Shandong, China.
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Źródło :
Bioengineered [Bioengineered] 2020 Dec; Vol. 11 (1), pp. 201-208.
Typ publikacji :
Journal Article
MeSH Terms :
Aminoquinolines/*therapeutic use
Antineoplastic Agents/*therapeutic use
MicroRNAs/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*metabolism
Thiosemicarbazones/*therapeutic use
Aminoquinolines/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Apoptosis/genetics ; Blotting, Western ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Densitometry ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Immunohistochemistry ; In Situ Nick-End Labeling ; Jurkat Cells/drug effects ; Jurkat Cells/metabolism ; Mice ; Mice, Nude ; MicroRNAs/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Thiosemicarbazones/pharmacology
Czasopismo naukowe
Tytuł :
Effect of nicotine on placental inflammation and apoptosis in preeclampsia-like model.
Autorzy :
Li X; First Affiliated Hospital of Jinan University, Guangzhou, China; Department of Obstetrics and Gynecology, Anhui Provincial Hospital, Anhui Medical University, Hefei, China; Department of Obstetrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zhou B; Department of Obstetrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Han X; Department of Obstetrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. Electronic address: .
Liu H; Department of Obstetrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118314. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation/*drug therapy
Nicotine/*pharmacology
Placenta/*drug effects
Pre-Eclampsia/*prevention & control
Adult ; Animals ; Apoptosis/drug effects ; Case-Control Studies ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Humans ; In Situ Nick-End Labeling ; Inflammation/pathology ; Lipopolysaccharides/toxicity ; Macrophages/metabolism ; Placenta/pathology ; Pre-Eclampsia/pathology ; Pregnancy ; RNA, Messenger ; Rats ; Rats, Sprague-Dawley ; Up-Regulation ; Young Adult
Czasopismo naukowe
Tytuł :
miR-27a promotion resulting from silencing of HDAC3 facilitates the recovery of spinal cord injury by inhibiting PAK6 expression in rats.
Autorzy :
Zhou Q; Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, PR China.
Feng X; Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, PR China.
Ye F; Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, PR China.
Lei F; Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, PR China.
Jia X; Department of Orthopaedics, The People's Hospital of Jianyang City, Jianyang 641400, PR China. Electronic address: .
Feng D; Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118098. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Silencing*
Histone Deacetylases/*genetics
MicroRNAs/*genetics
Spinal Cord Injuries/*therapy
p21-Activated Kinases/*genetics
Animals ; Apoptosis/physiology ; Disease Models, Animal ; Flow Cytometry ; Gene Expression/physiology ; Hydrogen Peroxide/pharmacology ; In Situ Nick-End Labeling ; Locomotion/physiology ; Male ; MicroRNAs/physiology ; Neurons/drug effects ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/metabolism ; Up-Regulation ; p21-Activated Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Nicotine induces apoptosis through exacerbation of blocked alveolar macrophage autophagic degradation in silicosis.
Autorzy :
Chen S; School of Medicine, Hunan Normal University, Changsha, Hunan Province 410013, PR China.
Tan S; School of Medicine, Hunan Normal University, Changsha, Hunan Province 410013, PR China.
Yang S; School of Medicine, Hunan Normal University, Changsha, Hunan Province 410013, PR China.
Chen G; Department of Pneumoconiosis, Beidaihe Sanitarium for China Coal Miners, Qinhuangdao, Hebei Province 066104, PR China.
Zhu L; Department of Pneumoconiosis, Beidaihe Sanitarium for China Coal Miners, Qinhuangdao, Hebei Province 066104, PR China.
Sun Z; Department of Pneumoconiosis, Beidaihe Sanitarium for China Coal Miners, Qinhuangdao, Hebei Province 066104, PR China.
Li H; School of Public Health, Xinxiang Medical University, Xinxiang, Henan Province, 453003, PR China.
Yao S; School of Public Health, Xinxiang Medical University, Xinxiang, Henan Province, 453003, PR China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Nov 01; Vol. 334, pp. 94-101. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Autophagy/*drug effects
Macrophages, Alveolar/*drug effects
Nicotine/*toxicity
Silicosis/*pathology
Adenine/analogs & derivatives ; Adenine/pharmacology ; Caspase 3/metabolism ; Cells, Cultured ; Humans ; In Situ Nick-End Labeling ; Lysosomes/drug effects ; Lysosomes/metabolism ; Lysosomes/pathology ; Macrophages, Alveolar/metabolism ; Macrophages, Alveolar/pathology ; Male ; Microtubule-Associated Proteins/metabolism ; Silicon Dioxide/toxicity ; Silicosis/metabolism
Czasopismo naukowe
Tytuł :
Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis.
Autorzy :
Cui JW; School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Institute of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hong Y; The First Rehabilitation Hospital of Shanghai, Shanghai, China.
Kuo YM; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yu SH; College of Rehabilitation, Shandong University of Traditional Chinese Medicine, Shandong, China.
Wu XB; School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Departmental of Rehabilitation, Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Cui ZY; School of Rehabilitation Medicine, Weifang Medical University, Shandong, China.
Lee SD; School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China; College of Rehabilitation, Shandong University of Traditional Chinese Medicine, Shandong, China; Departmental of Rehabilitation, Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China; School of Rehabilitation Medicine, Weifang Medical University, Shandong, China; Department of Physical Therapy, Asia University, Taichung, Taiwan; Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118187. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*physiology
Apoptosis/*physiology
Heart/*physiology
Physical Conditioning, Animal/*physiology
Animals ; In Situ Nick-End Labeling ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria, Heart/physiology ; Muscle, Skeletal/cytology ; Muscle, Skeletal/physiology ; Running/physiology ; Sedentary Behavior
Czasopismo naukowe
Tytuł :
Increased putrescine levels due to ODC1 overexpression prevents mitochondrial dysfunction-related apoptosis induced by methylmercury.
Autorzy :
Sato M; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Toyama T; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Kim MS; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; Inhalation Toxicology Research Group, Korea Institute of Toxicology, 30, Baekhak1-gil Jeongeup-si, Jeollabuk-do 56212, Republic of Korea.
Lee JY; Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan.
Hoshi T; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Miura N; Laboratory of Environmental and Molecular Toxicology, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, Kanagawa 245-0066, Japan.
Naganuma A; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Hwang GW; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; Laboratory of Environmental and Health Sciences, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 01; Vol. 256, pp. 118031. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Methylmercury Compounds/*toxicity
Mitochondria/*drug effects
Neural Stem Cells/*drug effects
Ornithine Decarboxylase/*genetics
Putrescine/*pharmacology
Animals ; Apoptosis/drug effects ; Cell Line ; In Situ Nick-End Labeling ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/pathology ; Neural Stem Cells/pathology
Czasopismo naukowe
Tytuł :
LncRNA Kcnq1ot1 renders cardiomyocytes apoptosis in acute myocardial infarction model by up-regulating Tead1.
Autorzy :
Liao B; Department of Cardiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China.
Dong S; Department of Cardiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China. Electronic address: .
Xu Z; Department of Gastroenterology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China. Electronic address: .
Gao F; Department of Cardiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China.
Zhang S; Department of Cardiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China.
Liang R; Department of Cardiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China.
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Źródło :
Life sciences [Life Sci] 2020 Sep 01; Vol. 256, pp. 117811. Date of Electronic Publication: 2020 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*genetics
Myocardial Infarction/*physiopathology
Myocytes, Cardiac/*pathology
RNA, Long Noncoding/*genetics
Animals ; DNA-Binding Proteins/genetics ; Disease Models, Animal ; In Situ Nick-End Labeling ; Male ; MicroRNAs/genetics ; Myocardial Infarction/genetics ; Nuclear Proteins/genetics ; Rats ; Rats, Sprague-Dawley ; Transcription Factors/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
BBSome Component BBS5 Is Required for Cone Photoreceptor Protein Trafficking and Outer Segment Maintenance.
Autorzy :
Bales KL; Department of Optometry and Vision Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Bentley MR; Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Croyle MJ; Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Kesterson RA; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Yoder BK; Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Gross AK; Department of Optometry and Vision Sciences, University of Alabama at Birmingham, Birmingham, Alabama, United States.; Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States.; Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 Aug 03; Vol. 61 (10), pp. 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Carrier Proteins/*metabolism
Cytoskeletal Proteins/*physiology
Phosphate-Binding Proteins/*physiology
Retinal Cone Photoreceptor Cells/*metabolism
Retinal Degeneration/*metabolism
Retinal Photoreceptor Cell Outer Segment/*metabolism
Animals ; Blotting, Western ; Cytoskeletal Proteins/metabolism ; Disease Models, Animal ; Electroretinography ; In Situ Nick-End Labeling ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron, Transmission ; Microscopy, Fluorescence ; Opsins/metabolism ; Phosphate-Binding Proteins/metabolism ; Protein Transport ; Retinal Cone Photoreceptor Cells/ultrastructure ; Retinal Degeneration/pathology ; Retinal Photoreceptor Cell Outer Segment/ultrastructure ; Retinal Rod Photoreceptor Cells/metabolism ; Retinal Rod Photoreceptor Cells/ultrastructure
Czasopismo naukowe
Tytuł :
Excessive fluoride exposure induces thymocyte apoptosis and impairs cell division: Roles of the PERK and IRE1 pathways.
Autorzy :
Wei W; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin, Heilongjiang, 150081, China; Institution of Environmentally Related Diseases, Harbin Medical University, Harbin, Heilongjiang, 150081, China. Electronic address: .
Wang Q; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
Pang S; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China; Qingdao Hospital of Traditional Chinese Medicine (Qingdao Hiser hospital), Qingdao, Shandong Province, 266033, China.
Tan S; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
Sun J; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
Li M; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
Wang S; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
Sun D; Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, 150081, China.
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Aug 01; Vol. 328, pp. 35-44. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cell Division/*drug effects
Fluorides/*toxicity
Membrane Proteins/*drug effects
Protein-Serine-Threonine Kinases/*drug effects
Signal Transduction/*drug effects
Thymocytes/*drug effects
eIF-2 Kinase/*drug effects
Animals ; B-Lymphocytes/drug effects ; CD3 Complex ; Cells, Cultured ; Gene Knockdown Techniques ; In Situ Nick-End Labeling ; Male ; Membrane Proteins/genetics ; Protein-Serine-Threonine Kinases/genetics ; Rats ; Rats, Wistar ; Thymus Gland/cytology ; Thymus Gland/drug effects ; eIF-2 Kinase/genetics
Czasopismo naukowe
Tytuł :
Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Autorzy :
Liu Q; Key Laboratory of Chemical Biology (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Shandong University, No. 44 Wenhuaxi Road, Jinan 250012, China.
Tan Y; Qilu Cell Therapy Technology Co., Ltd, Jinan 250000, China; Shandong Yinfeng Life Science Research Institute, Jinan, 250000, Shandong, China.
Qu T; Shandong Yinfeng Life Science Research Institute, Jinan, 250000, Shandong, China; R & D of Cell and Tissue Bank, Qilu Stem Cell Engineering Company of Shandong Province, Jinan 250000, Shandong, China.
Zhang J; Qilu Cell Therapy Technology Co., Ltd, Jinan 250000, China.
Duan X; Maternal and Child Health Care Hospital of Shandong Province, Jinan, 250014, Shandong, China.
Xu H; Qilu Cell Therapy Technology Co., Ltd, Jinan 250000, China.
Mu Y; Key Laboratory of Chemical Biology (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Shandong University, No. 44 Wenhuaxi Road, Jinan 250012, China.
Ma H; Qilu Cell Therapy Technology Co., Ltd, Jinan 250000, China; Shandong Yinfeng Life Science Research Institute, Jinan, 250000, Shandong, China. Electronic address: .
Wang F; Key Laboratory of Chemical Biology (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Shandong University, No. 44 Wenhuaxi Road, Jinan 250012, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Aug 01; Vol. 254, pp. 117772. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Extracellular Vesicles/*metabolism
Neural Stem Cells/*metabolism
Reperfusion Injury/*therapy
Apoptosis/drug effects ; Cell Survival/drug effects ; Extracellular Vesicles/physiology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Hypoxia/metabolism ; Hypoxia-Ischemia, Brain/metabolism ; In Situ Nick-End Labeling/methods ; Mesenchymal Stem Cells/metabolism ; NF-E2-Related Factor 2/metabolism ; Neural Stem Cells/physiology ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Apoptosis as a Prognostic Factor in Colorectal Carcinoma: Comparison of TUNEL Method and Immunohistochemical Expression of Caspase-3.
Autorzy :
Kunac N; Departments of Pathology, Forensic Medicine and Cytology.
Šundov Ž; Gastroenterology, Clinical Hospital Center Split, Split, Croatia.
Vilović K; Departments of Pathology, Forensic Medicine and Cytology.
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Źródło :
Applied immunohistochemistry & molecular morphology : AIMM [Appl Immunohistochem Mol Morphol] 2019 Mar; Vol. 27 (3), pp. e22-e27.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Apoptosis*
Colonic Neoplasms*/epidemiology
Colonic Neoplasms*/mortality
Colonic Neoplasms*/pathology
In Situ Nick-End Labeling*
Caspase 3/*metabolism
Neoplasm Proteins/*metabolism
Aged ; Disease-Free Survival ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Survival Rate
Czasopismo naukowe
Tytuł :
Development of Animal Models for Lens and Corneal Diseases Using N-Methyl-N-Nitrosourea.
Autorzy :
Qu Y; .; .
Li R; .
Li X; .
Yang Q; .
Chen J
Dong Y; .
Xiao W; .
Zheng S; .
Wang L; .
Tao Y; .
Huang Y; .
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 Jul 01; Vol. 61 (8), pp. 38.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Corneal Diseases*/etiology
Corneal Diseases*/pathology
Disease Models, Animal*
Lens Diseases*/etiology
Lens Diseases*/pathology
Rabbits*
Rats*
Methylnitrosourea/*pharmacology
Alkylating Agents/pharmacology ; Animals ; Apoptosis/drug effects ; Dose-Response Relationship, Drug ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Immunohistochemistry ; In Situ Nick-End Labeling ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Methoxytetrahydro-2H-pyran-2-yl)methyl benzoate inhibits spinal cord injury in the rat model via PPAR-γ/PI3K/p-Akt activation.
Autorzy :
Zhang H; Department of Spinal surgery, The People's Hospital of Longhua, Shenzhen, China.
Gong M; Department of Spinal surgery, The People's Hospital of Longhua, Shenzhen, China.
Luo X; Department of Spinal surgery, The People's Hospital of Longhua, Shenzhen, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2020 Jun; Vol. 35 (6), pp. 714-721. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
PPAR gamma/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Plant Extracts/*therapeutic use
Proto-Oncogene Proteins c-akt/*metabolism
Pyrans/*therapeutic use
Spinal Cord Injuries/*drug therapy
Animals ; Apoptosis/drug effects ; Behavior, Animal/drug effects ; Crataegus ; Cytokines/metabolism ; Disease Models, Animal ; In Situ Nick-End Labeling ; Inflammation ; Male ; Molecular Structure ; Oxidative Stress/drug effects ; Plant Extracts/isolation & purification ; Pyrans/isolation & purification ; Rats ; Rats, Sprague-Dawley ; Spinal Cord Injuries/metabolism ; Spinal Cord Injuries/pathology
Czasopismo naukowe
Tytuł :
Epigallocatechin gallate alleviates neuronal cell damage against focal cerebral ischemia in rats.
Autorzy :
Park DJ; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, 52828, South Korea.
Kang JB; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, 52828, South Korea.
Koh PO; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, 52828, South Korea.
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Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2020 May 20; Vol. 82 (5), pp. 639-645. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
Catechin/*analogs & derivatives
Neuroprotective Agents/*pharmacology
Animals ; Apoptosis/drug effects ; Caspase 3/metabolism ; Catechin/pharmacology ; Cerebral Infarction ; Disease Models, Animal ; In Situ Nick-End Labeling ; Infarction, Middle Cerebral Artery ; Male ; Poly(ADP-ribose) Polymerases/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe

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