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Tytuł :
Dutcher bodies in IgA multiple myeloma.
Autorzy :
Martino G; Hematology and Clinical Immunology, Centro di Ricerca Emato-Oncologica - C.R.E.O., University of Perugia, Piazzale Menghini, 8/9, 06132 (PG), Perugia, Italy. .
Zanelli M; Pathology Unit, Azienda Unità Sanitaria Locale/IRCCS Reggio Emilia, Reggio Emilia, Italy.
Zizzo M; Surgical Oncology Unit, Azienda Unità Sanitaria Locale/IRCCS Reggio Emilia, Reggio Emilia, Italy.; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.
Ricci L; Hematology and Clinical Immunology, Centro di Ricerca Emato-Oncologica - C.R.E.O., University of Perugia, Piazzale Menghini, 8/9, 06132 (PG), Perugia, Italy.
Ascani S; Department of Experimental Medicine-Section of Pathologic Anatomy and Histology Medical School, University of Perugia, Perugia, Italy.
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Źródło :
Annals of hematology [Ann Hematol] 2020 Sep; Vol. 99 (9), pp. 2205-2206. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Bone Marrow/*pathology
Inclusion Bodies/*ultrastructure
Multiple Myeloma/*pathology
Plasma Cells/*ultrastructure
Cell Nucleus/ultrastructure ; Eosine Yellowish-(YS) ; Humans ; Immunoglobulin A/analysis ; Intranuclear Inclusion Bodies/ultrastructure ; Male ; Middle Aged ; Myeloma Proteins/analysis ; Staining and Labeling
Raport
Tytuł :
Ebola Virus Inclusion Body Formation and RNA Synthesis Are Controlled by a Novel Domain of Nucleoprotein Interacting with VP35.
Autorzy :
Miyake T; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Farley CM; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Neubauer BE; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Beddow TP; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Hoenen T; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Engel DA; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA .
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Źródło :
Journal of virology [J Virol] 2020 Jul 30; Vol. 94 (16). Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Ebolavirus/*metabolism
Inclusion Bodies, Viral/*metabolism
Nucleoproteins/*physiology
Cell Line ; Ebolavirus/pathogenicity ; Genome, Viral/genetics ; HEK293 Cells ; Hemorrhagic Fever, Ebola/virology ; Humans ; Inclusion Bodies/metabolism ; Nucleocapsid/metabolism ; Nucleocapsid/physiology ; Nucleocapsid Proteins/metabolism ; Nucleocapsid Proteins/physiology ; Nucleoproteins/metabolism ; RNA/biosynthesis ; RNA, Viral/genetics ; Transcription Factors/metabolism ; Viral Proteins/metabolism ; Viral Regulatory and Accessory Proteins/metabolism ; Viral Regulatory and Accessory Proteins/physiology ; Virion/metabolism ; Virus Replication/physiology
Czasopismo naukowe
Tytuł :
PML nuclear bodies and chromatin dynamics: catch me if you can!
Autorzy :
Corpet A; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Kleijwegt C; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Roubille S; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Juillard F; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Jacquet K; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Texier P; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
Lomonte P; Univ Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U 1217, LabEx DEVweCAN, Institut NeuroMyoGène (INMG), team Chromatin Dynamics, Nuclear Domains, Virus F-69008, Lyon, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11890-11912.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genome, Viral*
Protein Processing, Post-Translational*
Cell Nucleus/*metabolism
Chromatin/*metabolism
Intranuclear Inclusion Bodies/*metabolism
Promyelocytic Leukemia Protein/*genetics
Cell Nucleus/genetics ; Cell Nucleus/ultrastructure ; Cell Nucleus/virology ; Cellular Senescence ; Chromatin/chemistry ; Chromatin/ultrastructure ; Chromatin Assembly and Disassembly ; Genome, Human ; Histones/genetics ; Histones/metabolism ; Host-Pathogen Interactions/genetics ; Humans ; Intranuclear Inclusion Bodies/chemistry ; Intranuclear Inclusion Bodies/ultrastructure ; Promyelocytic Leukemia Protein/metabolism ; Small Ubiquitin-Related Modifier Proteins/genetics ; Small Ubiquitin-Related Modifier Proteins/metabolism ; Sumoylation ; Telomere Homeostasis ; Viruses/genetics ; Viruses/metabolism
Czasopismo naukowe
Tytuł :
Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5.
Autorzy :
Oikawa Y; Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Izumi R; Division of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Koide M; Department of Orthopedics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hagiwara Y; Department of Orthopedics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kanzaki M; Department of Biomedical Engineering, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
Suzuki N; Division of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kikuchi K; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Matsuhashi T; Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Akiyama Y; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ichijo M; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Watanabe S; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, Sendai, Japan.
Toyohara T; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
Suzuki T; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, Sendai, Japan.
Mishima E; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Akiyama Y; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ogata Y; Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
Suzuki C; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hayashi H; Division of Infectious Diseases, International Institute of Disaster Science, Graduate School of Medicine, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Intelligent Network for Infection Control, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Kodama EN; Division of Infectious Diseases, International Institute of Disaster Science, Graduate School of Medicine, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Hayashi KI; Department of Biochemistry, Okayama University of Science, Okayama, Japan.
Itoi E; Department of Orthopedics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Aoki M; Division of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kure S; Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Abe T; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Clinical Biology and Hormonal Regulation, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
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Źródło :
PloS one [PLoS One] 2020 Dec 02; Vol. 15 (12), pp. e0231064. Date of Electronic Publication: 2020 Dec 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Indoleacetic Acids/*therapeutic use
Mitochondria, Muscle/*metabolism
Myositis, Inclusion Body/*drug therapy
Phenylbutyrates/*therapeutic use
Adenosine Triphosphate/biosynthesis ; Aged ; Aged, 80 and over ; Buthionine Sulfoximine/pharmacology ; Cell Survival/drug effects ; Cells, Cultured ; DNA, Mitochondrial/genetics ; Drug Evaluation, Preclinical ; Dynamins/biosynthesis ; Dynamins/genetics ; Female ; Fibroblast Growth Factors/blood ; Fibroblasts/drug effects ; GTP Phosphohydrolases/biosynthesis ; GTP Phosphohydrolases/genetics ; Growth Differentiation Factor 15/biosynthesis ; Growth Differentiation Factor 15/blood ; Growth Differentiation Factor 15/genetics ; Humans ; Indoleacetic Acids/pharmacology ; Male ; Middle Aged ; Mitochondria, Muscle/pathology ; Myoblasts/drug effects ; Myoblasts/metabolism ; Myoblasts/ultrastructure ; Myositis, Inclusion Body/metabolism ; Myositis, Inclusion Body/pathology ; Oxygen Consumption ; Phenylbutyrates/pharmacology ; Reactive Oxygen Species/metabolism ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Supporting Inclusive Learning Environments and Professional Development in Medical Education Through an Identity and Inclusion Initiative.
Autorzy :
Woodruff JN; J.N. Woodruff is professor and dean of students, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. M.B. Vela is professor and associate dean of multicultural affairs, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. Z. Zayyad is a student, medical scientist training program, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. T.A. Johnson is a resident, University of San Francisco Medical Center, San Francisco, California. B. Kyalwazi is a student, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. C. Amegashie is a student, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. R. Silverman is education and operations manager, Department of Surgery, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. D. Levinson is associate dean for medical school administration, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. K. Blythe is executive director of student affairs, UME finance, and continuum strategy, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. W.W. Lee is associate professor and associate dean of students, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. S. Thomas is administrator, Department of Anesthesia, Johns Hopkins University, Baltimore, Maryland. W. Parrish is director of multicultural affairs, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois. H.J. Humphrey is president, Josiah Macy Jr. Foundation, New York, New York.
Vela MB
Zayyad Z
Johnson TA
Kyalwazi B
Amegashie C
Silverman R
Levinson D
Blythe K
Lee WW
Thomas S
Parrish W
Humphrey HJ
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2020 Dec; Vol. 95 (12S Addressing Harmful Bias and Eliminating Discrimination in Health Professions Learning Environments), pp. S51-S57.
Typ publikacji :
Journal Article
MeSH Terms :
Social Identification*
Social Inclusion*
Education, Medical/*trends
Staff Development/*methods
Education, Medical/methods ; Education, Medical/standards ; Humans ; Interprofessional Relations ; Learning
Czasopismo naukowe
Tytuł :
Toward a Bias-Free and Inclusive Medical Curriculum: Development and Implementation of Student-Initiated Guidelines and Monitoring Mechanisms at One Institution.
Autorzy :
Benoit LJ; L.J. Benoit is an MD-PhD student, Columbia University Vagelos College of Physicians and Surgeons, New York, New York; ORCID: http://orcid.org/0000-0002-3735-027X. C. Travis is a second-year resident, obstetrics and gynecology, University of Southern California, Los Angeles, California. A.S. Sein is director, Center for Education Research and Evaluation, and assistant professor, educational assessment, Columbia University Vagelos College of Physicians and Surgeons, New York, New York; ORCID: http://orcid.org/0000-0002-3139-4626. S.C. Quiah is associate director, Center for Education Research and Evaluation, Columbia University Vagelos College of Physicians and Surgeons, New York, New York. J. Amiel is interim co-vice dean for education and senior associate dean for curricular affairs, Columbia University Vagelos College of Physicians and Surgeons, New York, New York. D. Gowda is assistant dean, medical education, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California.
Travis C
Swan Sein A
Quiah SC
Amiel J
Gowda D
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2020 Dec; Vol. 95 (12S Addressing Harmful Bias and Eliminating Discrimination in Health Professions Learning Environments), pp. S145-S149.
Typ publikacji :
Journal Article
MeSH Terms :
Bias*
Guidelines as Topic*
Social Inclusion*
Curriculum/*standards
Curriculum/trends ; Education, Medical, Undergraduate/methods ; Humans ; New York City
Czasopismo naukowe
Tytuł :
Building Equity, Inclusion, and Diversity Into the Fabric of a New Medical School: Early Experiences of the Kaiser Permanente Bernard J. Tyson School of Medicine.
Autorzy :
Schuster MA; M.A. Schuster is founding dean and chief executive officer, and professor, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California. W.D. Conwell is associate dean, Equity, Inclusion, and Diversity, and assistant professor, Department of Clinical Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California. M.T. Connelly is senior associate dean, Academic and Community Affairs, and professor, Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California. H.J. Humphrey is president, Josiah Macy Jr. Foundation, New York, New York, and chair, Kaiser Permanente Bernard J. Tyson School of Medicine Board of Directors, Pasadena, California.
Conwell WD
Connelly MT
Humphrey HJ
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2020 Dec; Vol. 95 (12S Addressing Harmful Bias and Eliminating Discrimination in Health Professions Learning Environments), pp. S66-S70.
Typ publikacji :
Journal Article
MeSH Terms :
Cultural Diversity*
Social Inclusion*
Health Equity/*standards
Schools, Medical/*trends
American Medical Association/organization & administration ; Health Equity/trends ; Humans ; Leadership ; Schools, Medical/organization & administration ; United States
Czasopismo naukowe
Tytuł :
How Medical Educators Can Foster Equity and Inclusion in Their Teaching: A Faculty Development Workshop Series.
Autorzy :
Lupton KL; K.L. Lupton is associate professor, Department of Medicine, University of California, San Francisco, San Francisco, California. P.S. O'Sullivan is professor, Department of Medicine and Department of Surgery, and director, education research and faculty development, University of California, San Francisco Center for Faculty Educators, University of California, San Francisco, San Francisco, California.
O'Sullivan PS
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2020 Dec; Vol. 95 (12S Addressing Harmful Bias and Eliminating Discrimination in Health Professions Learning Environments), pp. S71-S76.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Social Inclusion*
Faculty, Medical/*education
Staff Development/*methods
Teaching/*standards
Education/methods ; Education, Medical, Continuing/methods ; Faculty, Medical/trends ; Humans ; San Francisco ; Staff Development/trends ; Teaching/psychology ; Teaching/trends
Czasopismo naukowe
Tytuł :
Negri bodies and other virus membrane-less replication compartments.
Autorzy :
Nevers Q; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Albertini AA; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Lagaudrière-Gesbert C; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France.
Gaudin Y; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Dec; Vol. 1867 (12), pp. 118831. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Viral Replication Compartments*
Inclusion Bodies, Viral/*genetics
Rabies/*genetics
Virus Replication/*genetics
Cell Membrane/genetics ; Inclusion Bodies, Viral/virology ; Rabies/virology ; Rabies virus/genetics ; Rabies virus/pathogenicity ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Beyond Technical Standards: A Competency-Based Framework for Access and Inclusion in Medical Education.
Autorzy :
Curry RH; R.H. Curry is professor of medicine and medical education, University of Illinois at Chicago, and senior associate dean, educational affairs, University of Illinois College of Medicine, Chicago, Illinois; ORCID: http://orcid.org/0000-0003-3381-0125. L.M. Meeks is assistant professor of family medicine, University of Michigan Medical School, Ann Arbor, Michigan, and researcher, Center for a Diverse Healthcare Workforce, University of California, Davis, School of Medicine, Sacramento, California; ORCID: http://orcid.org/0000-0002-3647-3657. L.I. Iezzoni is professor of medicine, Harvard Medical School, and Health Policy Research Center, Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts; ORCID: http://orcid.org/0000-0002-1416-5039.
Meeks LM
Iezzoni LI
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2020 Dec; Vol. 95 (12S Addressing Harmful Bias and Eliminating Discrimination in Health Professions Learning Environments), pp. S109-S112.
Typ publikacji :
Journal Article
MeSH Terms :
Reference Standards*
Social Inclusion*
Education, Medical/*methods
Clinical Competence/standards ; Competency-Based Education/methods ; Disabled Persons/education ; Education, Medical/trends ; Humans ; Social Justice
Czasopismo naukowe
Tytuł :
Author response: Granulomatosis-associated myositis: High prevalence of sporadic inclusion body myositis.
Autorzy :
Dieudonné Y; (Strasbourg, France).
Meyer A; (Strasbourg, France).
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Źródło :
Neurology [Neurology] 2020 Dec 01; Vol. 95 (22), pp. 1024.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Myositis*/complications
Myositis*/epidemiology
Myositis, Inclusion Body*/epidemiology
Humans ; Prevalence
Czasopismo naukowe
Tytuł :
Association of Ultraviolet Radiation Exposure With Dermatomyositis in a National Myositis Patient Registry.
Autorzy :
Parks CG; National Institute of Environmental Health Sciences/NIH, Durham, North Carolina.
Wilkerson J; Social Scientific & Systems, Durham, North Carolina.
Rose KM
Faiq A; National Institute of Environmental Health Sciences/NIH,, Bethesda, Maryland.
Noroozi Farhadi P; National Institute of Environmental Health Sciences/NIH,, Bethesda, Maryland.
Long CS; National Oceanic and Atmospheric Administration/National Weather Service, National Centers for Environmental Prediction Climate Prediction Center, College Park, Maryland.
Bayat N; National Institute of Environmental Health Sciences/NIH,, Bethesda, Maryland.
Brunner HI; Cincinnati Children's Medical Center, Cincinnati, Ohio.
Goldberg B; The Myositis Association, Alexandria, Virginia.
McGrath JA; Social Scientific & Systems, Durham, North Carolina.
Miller FW; National Institute of Environmental Health Sciences/NIH,, Bethesda, Maryland.
Rider LG; National Institute of Environmental Health Sciences/NIH,, Bethesda, Maryland.
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Źródło :
Arthritis care & research [Arthritis Care Res (Hoboken)] 2020 Nov; Vol. 72 (11), pp. 1636-1644.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Dermatomyositis/*etiology
Myositis, Inclusion Body/*etiology
Polymyositis/*etiology
Radiation Exposure/*adverse effects
Ultraviolet Rays/*adverse effects
Adolescent ; Adult ; Aged ; Dermatomyositis/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Myositis, Inclusion Body/epidemiology ; Polymyositis/epidemiology ; Registries ; Spatial Analysis ; Sunburn/complications ; Surveys and Questionnaires ; United States/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Prevalence of inclusion body disease and associated comorbidity in captive collections of boid and pythonid snakes in Belgium.
Autorzy :
Simard J; Division of Poultry, Department of Pathology, Bacteriology and Avian Diseases, Exotic Companion Animals, Wildlife and Experimental Animals, Ghent University, Merelbeke, Belgium.
Marschang RE; Laboklin GmbH & Co. KG, Bad Kissingen, Germany.
Leineweber C; Laboklin GmbH & Co. KG, Bad Kissingen, Germany.
Hellebuyck T; Division of Poultry, Department of Pathology, Bacteriology and Avian Diseases, Exotic Companion Animals, Wildlife and Experimental Animals, Ghent University, Merelbeke, Belgium.
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Źródło :
PloS one [PLoS One] 2020 Mar 02; Vol. 15 (3), pp. e0229667. Date of Electronic Publication: 2020 Mar 02 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Boidae/*metabolism
Cytomegalovirus Infections/*epidemiology
Inclusion Bodies/*metabolism
Animals ; Animals, Zoo ; Arenaviridae/pathogenicity ; Belgium/epidemiology ; Comorbidity ; Cross-Sectional Studies ; Inclusion Bodies/physiology ; Inclusion Bodies, Viral/genetics ; Prevalence ; RNA, Viral/genetics ; Snakes/genetics
Czasopismo naukowe
Tytuł :
Structures of α-synuclein filaments from multiple system atrophy.
Autorzy :
Schweighauser M; MRC Laboratory of Molecular Biology, Cambridge, UK.
Shi Y; MRC Laboratory of Molecular Biology, Cambridge, UK.
Tarutani A; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Kametani F; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Murzin AG; MRC Laboratory of Molecular Biology, Cambridge, UK.
Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Matsubara T; Department of Neuropathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Tomita T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Ando T; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hasegawa K; Division of Neurology, Sagamihara National Hospital, Sagamihara, Japan.
Murayama S; Department of Neuropathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Yoshida M; Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan.
Hasegawa M; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Scheres SHW; MRC Laboratory of Molecular Biology, Cambridge, UK. .
Goedert M; MRC Laboratory of Molecular Biology, Cambridge, UK. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7825), pp. 464-469. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy*
Brain/*metabolism
Inclusion Bodies/*chemistry
Inclusion Bodies/*ultrastructure
Multiple System Atrophy/*metabolism
alpha-Synuclein/*chemistry
alpha-Synuclein/*ultrastructure
Brain/pathology ; Brain/ultrastructure ; Humans ; Inclusion Bodies/metabolism ; Inclusion Bodies/pathology ; Models, Molecular ; Multiple System Atrophy/diagnosis ; Multiple System Atrophy/pathology ; Multiple System Atrophy/therapy ; Protein Folding ; Putamen/metabolism ; Putamen/ultrastructure ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Conceptualization of Roma in Policy Documents Related to Social Inclusion and Health in the Czech Republic.
Autorzy :
Slepickova L; Olomouc University Social Health Institute, Theological Faculty, Palacky University Olomouc, 771 11 Olomouc, Czech Republic.
Bobakova DF; Olomouc University Social Health Institute, Theological Faculty, Palacky University Olomouc, 771 11 Olomouc, Czech Republic.; Department of Health Psychology and Research Methodology, Faculty of Medicine, Pavol Jozef Safarik University, 040 01 Kosice, Slovakia.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Oct 22; Vol. 17 (21). Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Health Policy*
Roma*
Social Inclusion*
Concept Formation ; Czech Republic ; Humans
Czasopismo naukowe
Tytuł :
Swine Promyelocytic Leukemia Isoform II Inhibits Pseudorabies Virus Infection by Suppressing Viral Gene Transcription in Promyelocytic Leukemia Nuclear Bodies.
Autorzy :
Yu C; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Xu A; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Lang Y; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Qin C; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang M; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yuan X; Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Sun S; Shandong Provincial Center for Animal Disease Control and Prevention, Jinan, China.
Feng W; State Key Laboratory of Agrobiotechnology and Department of Microbiology and Immunology, College of Biological Sciences, China Agricultural University, Beijing, China.
Gao C; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Chen J; College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhang R; College of Veterinary Medicine, China Agricultural University, Beijing, China .
Tang J; College of Veterinary Medicine, China Agricultural University, Beijing, China .
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Źródło :
Journal of virology [J Virol] 2020 Aug 31; Vol. 94 (18). Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
Herpesvirus 1, Suid/*genetics
Intranuclear Inclusion Bodies/*genetics
Promyelocytic Leukemia Protein/*genetics
Viral Proteins/*genetics
Animals ; Cell Line ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; Gene Expression Regulation ; HEK293 Cells ; Herpesvirus 1, Suid/metabolism ; Herpesvirus 1, Suid/pathogenicity ; Host-Pathogen Interactions/genetics ; Humans ; Intranuclear Inclusion Bodies/metabolism ; Intranuclear Inclusion Bodies/virology ; Macrophages/metabolism ; Macrophages/virology ; Promyelocytic Leukemia Protein/metabolism ; Protein Domains ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Signal Transduction ; Structure-Activity Relationship ; Sumoylation ; Swine ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation.
Autorzy :
Radwan M; Department of Biochemistry and Molecular Biology; and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
Lilley JD; Department of Biochemistry and Molecular Biology; and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
Ang CS; Bio21 Mass Spectrometry and Proteomics Facility, The University of Melbourne, Parkville, Victoria, Australia.
Reid GE; Department of Biochemistry and Molecular Biology; and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.; School of Chemistry, The University of Melbourne, Parkville, VIC, Australia.
Hatters DM; Department of Biochemistry and Molecular Biology; and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.
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Źródło :
PloS one [PLoS One] 2020 Aug 28; Vol. 15 (8), pp. e0233247. Date of Electronic Publication: 2020 Aug 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inclusion Bodies/*metabolism
Peptides/*metabolism
Proteins/*metabolism
Animals ; C9orf72 Protein/genetics ; C9orf72 Protein/metabolism ; Cell Line ; Exons ; Humans ; Huntingtin Protein/genetics ; Huntingtin Protein/metabolism ; Inclusion Bodies/genetics ; Inclusion Bodies/pathology ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Mice ; Microscopy, Confocal ; Mutation ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology ; Peptides/genetics ; Protein Aggregation, Pathological/genetics ; Protein Aggregation, Pathological/metabolism ; Protein Aggregation, Pathological/pathology ; Proteins/genetics ; Proteolysis ; Proteome/genetics ; Proteome/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Risk Factors ; Solubility
Czasopismo naukowe
Tytuł :
HLA-DRB1 allele and autoantibody profiles in Japanese patients with inclusion body myositis.
Autorzy :
Oyama M; Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
Ohnuki Y; Department of Medial Ethics, Tokai University School of Medicine, Kanagawa, Japan.
Inoue M; Department of Neuromuscular Research, National Institute of Neuroscience, and Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Uruha A; Department of Neuropathology, Charité-Universitätsmedizin, Berlin, Germany.
Yamashita S; Depertment of Neurology, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.
Yutani S; Department of Neurology, Tokai University School of Medicine, Isehara-shi, Kanagawa, Japan.
Tanboon J; Department of Neuromuscular Research, National Institute of Neuroscience, and Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Nakahara J; Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
Suzuki S; Department of Molecular Life Science, Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Shiina T; Department of Molecular Life Science, Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Nishino I; Department of Neuromuscular Research, National Institute of Neuroscience, and Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Suzuki S; Department of Neurology, Keio University School of Medicine, Tokyo, Japan.
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Źródło :
PloS one [PLoS One] 2020 Aug 18; Vol. 15 (8), pp. e0237890. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
Asian Continental Ancestry Group/*genetics
Autoantibodies/*blood
HLA-DRB1 Chains/*genetics
HLA-DRB1 Chains/*immunology
Myositis, Inclusion Body/*blood
Myositis, Inclusion Body/*genetics
Aged ; Antibodies, Viral/immunology ; Female ; Gene Frequency/genetics ; Hepacivirus/immunology ; Humans ; Male ; Myositis, Inclusion Body/immunology
Czasopismo naukowe
Tytuł :
Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
Autorzy :
Wang C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Duan Y; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Duan G; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Wang Q; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
Zhang K; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Deng X; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Qian B; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Gu J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Ma Z; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
Zhang S; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
Guo L; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Liu C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: .
Fang Y; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Aug 06; Vol. 79 (3), pp. 443-458.e7. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyotrophic Lateral Sclerosis/*genetics
DNA-Binding Proteins/*genetics
Intranuclear Inclusion Bodies/*metabolism
Neurons/*metabolism
RNA, Long Noncoding/*genetics
Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Animals, Genetically Modified ; Arsenites/pharmacology ; Cerebral Cortex/drug effects ; Cerebral Cortex/metabolism ; Cerebral Cortex/ultrastructure ; Cytoplasmic Granules/drug effects ; Cytoplasmic Granules/metabolism ; Cytoplasmic Granules/ultrastructure ; DNA-Binding Proteins/metabolism ; Disease Models, Animal ; Drosophila melanogaster ; Gene Expression Regulation ; HEK293 Cells ; HeLa Cells ; Humans ; Intranuclear Inclusion Bodies/drug effects ; Intranuclear Inclusion Bodies/ultrastructure ; Mice ; Mutation ; Neurons/drug effects ; Neurons/ultrastructure ; Primary Cell Culture ; Protein Transport/drug effects ; RNA, Long Noncoding/metabolism ; Signal Transduction ; Stress, Physiological
Czasopismo naukowe

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