Temat: "Indoles" - OpacWWW

Skocz do pozycji: 21.

Tytuł:: The efficacy and safety of vincristine, irinotecan and anlotinib in Epithelioid Sarcoma.
Autorzy:: Xie L; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Sun X; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Xu J; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Liang X; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Liu K; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Sun K; Pathology Department, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Yang R; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.
Tang X; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China. .
Guo W; Musculoskeletal Tumor Center, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, P. R. China.; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2024 Feb 03; Vol. 24 (1), pp. 172. Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:: Journal Article
MeSH Terms:: Sarcoma*/pathology
Biphenyl Compounds*
Benzamides*
Morpholines*
Quinolines*
Indoles*
Pyridones*
Humans ; Irinotecan/therapeutic use ; Vincristine/therapeutic use ; Retrospective Studies ; Antineoplastic Combined Chemotherapy Protocols/adverse effects

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 22.

Tytuł:: Investigation of Gastrointestinal Toxicities Associated with Concurrent Abdominal Radiation Therapy and the Tyrosine Kinase Inhibitor Sunitinib in a Mouse Model.
Autorzy:: Prebble AR; Veterinary Teaching Hospital, Colorado State University, Fort Collins, CO 80523, USA.
Latka B; Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Burdekin B; Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Leary D; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Harris M; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Regan D; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Boss MK; Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:: Journal Article
MeSH Terms:: Tyrosine Kinase Inhibitors*
Indoles*/therapeutic use
Humans ; Animals ; Dogs ; Mice ; Sunitinib/adverse effects ; Ki-67 Antigen ; Pyrroles/adverse effects ; Protein Kinase Inhibitors/adverse effects ; Disease Models, Animal ; Weight Loss

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 23.

Tytuł:: Efficacy of osimertinib in patients with EGFR-mutation positive non-small cell lung cancer with malignant pleural effusion.
Autorzy:: Kiritani A; Department of Respiratory Medicine, Jikei University School of Medicine, Minato, Japan.; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Amino Y; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Uchibori K; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Akita T; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.; Department of Respiratory Medicine, Hachinohe City Hospital, Hachinohe, Japan.
Harutani Y; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.; Department of Internal Medicine III, Wakayama Medical University, Wakayama, Japan.
Ogusu S; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Tsugitomi R; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Manabe R; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.; Division of Allergology and Respiratory Medicine, Department of Internal Medicine, Showa University School of Medicine, Shinagawa, Japan.
Ariyasu R; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Kitazono S; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Yanagitani N; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.
Nishio M; Department of Thoracic Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto, Japan.; Pokaż więcej
Źródło:: Thoracic cancer [Thorac Cancer] 2024 Feb; Vol. 15 (5), pp. 402-409. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Pleural Effusion, Malignant*/drug therapy
Pleural Effusion, Malignant*/genetics
Acrylamides*
Aniline Compounds*
Indoles*
Pyrimidines*
Humans ; ErbB Receptors/genetics ; Retrospective Studies ; Protein Kinase Inhibitors ; Mutation ; Neoplasm Recurrence, Local

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 24.

Tytuł:: Combination of Osimertinib and Olaparib Therapy to Treat Non-Small Cell Lung Cancer and High-Grade Serous Ovarian Carcinoma: A Case Report.
Autorzy:: Lin J; Schulich School of Medicine & Dentistry, Western University, London, ON N6A 3K7, Canada.
Welch S; Division of Medical Oncology, Department of Oncology, Western University, London, ON N6A 3K7, Canada.
Sanatani M; Division of Medical Oncology, Department of Oncology, Western University, London, ON N6A 3K7, Canada.
Ramadan S; Postgraduate Medical Education, Department of Oncology, Western University, London, ON N6A 3K7, Canada.; Pokaż więcej
Źródło:: Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Jan 19; Vol. 31 (1), pp. 558-565. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Case Reports
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Phthalazines*
Piperazines*
Acrylamides*
Aniline Compounds*
Indoles*
Pyrimidines*
Female ; Humans ; Aged ; Carcinoma, Ovarian Epithelial

Raport

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 25.

Tytuł:: Fabricating Polymer/Surfactant/Cyclodextrin Hybrid Particles for Possible Nose-to-Brain Delivery of Ropinirole Hydrochloride: In Vitro and Ex Vivo Evaluation.
Autorzy:: Saitani EM; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Pippa N; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Perinelli DR; School of Pharmacy, Chemistry Interdisciplinary Project (CHIP), University of Camerino, Via Madonna delle Carceri, 62032 Camerino, Italy.
Forys A; Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34, M. Curie-Skłodowskiej St, 41-819 Zabrze, Poland.
Papakyriakopoulou P; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Lagopati N; Laboratory of Biology, Department of Basic Medical Science, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
Bonacucina G; School of Pharmacy, Chemistry Interdisciplinary Project (CHIP), University of Camerino, Via Madonna delle Carceri, 62032 Camerino, Italy.
Trzebicka B; Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34, M. Curie-Skłodowskiej St, 41-819 Zabrze, Poland.
Gazouli M; Laboratory of Biology, Department of Basic Medical Science, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Pispas S; Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece.
Valsami G; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/drug therapy
Pulmonary Surfactants*
Indoles*
Humans ; Animals ; Rabbits ; Surface-Active Agents ; Polymers ; HEK293 Cells ; Brain ; Lipoproteins ; Nasal Mucosa

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 26.

Tytuł:: Establishment of Polydopamine-Modified HK-2 Cell Membrane Chromatography and Screening of Active Components from Plantago asiatica L.
Autorzy:: Gao H; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230029, China.
Liu Z; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230029, China.
Song F; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Xing J; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Zheng Z; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Hou Z; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Liu S; State Key Laboratory of Electroanalytical Chemistry & Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230029, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Plantago*
Gout*
Indoles*
Polymers*
Humans ; Silica Gel ; Silicon Dioxide ; Cell Membrane ; Membrane Proteins ; Kidney ; Chromatography ; Excipients

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 27.

Tytuł:: A new treatment for breast cancer using a combination of two drugs: AZD9496 and palbociclib.
Autorzy:: Nave O; Department of Mathematics, Faculty of Science, Jerusalem College of Technology (JCT), Academic Level Centre, Jerusalem, Israel. .
Shor Y; Department of Computer Science, Jerusalem College of Technology (Mivchar), Jerusalem, Israel.
Bar R; Department of Computer Science, Jerusalem College of Technology (Mivchar), Jerusalem, Israel.
Segal EE; Department of Computer Science, Jerusalem College of Technology (Mivchar), Jerusalem, Israel.
Sigron M; Department of Mathematics, Faculty of Science, Jerusalem College of Technology (JCT), Academic Level Centre, Jerusalem, Israel.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 15; Vol. 14 (1), pp. 1307. Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Cinnamates*
Indoles*
Humans ; Female ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Piperazines/pharmacology ; Piperazines/therapeutic use ; Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinase 6 ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 28.

Tytuł:: Lipid alterations play a role in the integration of PD-1/PD-L1 inhibitors and anlotinib for the treatment of advanced non-small-cell lung cancer.
Autorzy:: Liu L; The Second Affiliated Hospital of Soochow University, Suzhou, China.; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China.
Zhang S; Zhu Zhou Central Hospital, Zhuzhou, 412007, China.
Yang HY; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China.
Zhou CH; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China.
Xiong Y; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China.
Yang N; Department of Medical Oncology, Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China. .
Tian Y; The Second Affiliated Hospital of Soochow University, Suzhou, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2024 Jan 13; Vol. 23 (1), pp. 16. Date of Electronic Publication: 2024 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Indoles*
Quinolines*
Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Programmed Cell Death 1 Receptor/therapeutic use ; Lipids/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 29.

Tytuł:: Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate.
Autorzy:: Cooper E; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Oyagawa CRM; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Johnson R; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Foliaki JM; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Correia J; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Schweder P; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Heppner P; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Mee E; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Neurosurgery, Auckland City Hospital, Private Bag 92024, Auckland, 1142, New Zealand.
Turner C; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Anatomical Pathology, Auckland City Hospital, 2 Park Road, LabPlus, Auckland, New Zealand.
Faull R; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Dragunow M; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .
Jose J; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .
Park TI; Department of Pharmacology, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .; Neurosurgery Research Unit, The Centre for Brain Research, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 11; Vol. 22 (1), pp. 30. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carbocyanines*
Cytostatic Agents*/pharmacology
Cytostatic Agents*/therapeutic use
Glioblastoma*/drug therapy
Glioblastoma*/metabolism
Indoles*
Piperazines*
Pyridines*
Humans ; Apoptosis ; Cell Line, Tumor ; Receptors, Tumor Necrosis Factor/physiology ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Tumor Microenvironment ; Tumor Necrosis Factor-alpha/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 30.

Tytuł:: Bioaccessible Organosulfur Compounds in Broccoli Stalks Modulate the Inflammatory Mediators Involved in Inflammatory Bowel Disease.
Autorzy:: Costa-Pérez A; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Sánchez-Bravo P; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.; Centro de Investigación e Innovación Agroalimentaria y Agroambiental (CIAGRO), Universidad Miguel Hernández de Elche (UMH), Carretera de Beniel km 3.2, 03312 Orihuela, Alicante, Spain.
Medina S; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Domínguez-Perles R; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
García-Viguera C; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 08; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:: Journal Article
MeSH Terms:: Brassica*
Inflammatory Bowel Diseases*/drug therapy
Glucosinolates*
Indoles*
Sulfoxides*
Isothiocyanates*
Humans ; Caco-2 Cells ; Cytokines ; Inflammation Mediators ; Anti-Inflammatory Agents/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 31.

Tytuł:: DSC, TGA-FTIR and FTIR Assisted by Chemometric Factor Analysis and PXRD in Assessing the Incompatibility of the Antiviral Drug Arbidol Hydrochloride with Pharmaceutical Excipients.
Autorzy:: Rojek B; Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Gen. J. Hallera 107, 80-416 Gdansk, Poland.
Bartyzel A; Department of General, Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, Maria Curie-Sklodowska Sq. 2, 20-031 Lublin, Poland.
Sawicki W; Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Gen. J. Hallera 107, 80-416 Gdansk, Poland.
Plenis A; Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Gen. J. Hallera 107, 80-416 Gdansk, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 04; Vol. 29 (1). Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Chemometrics*
Chitosan*
Indoles*
Sulfides*
Calorimetry, Differential Scanning ; Excipients ; Spectroscopy, Fourier Transform Infrared ; X-Ray Diffraction ; Factor Analysis, Statistical ; Hydrochloric Acid ; Antiviral Agents

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 32.

Tytuł:: Pinpointing top inhibitors for GSK3β from pool of indirubin derivatives using rigorous computational workflow and their validation using molecular dynamics (MD) simulations.
Autorzy:: Pandya V; L. J. School of Applied Sciences, L. J. University, Sarkhej, Ahmedabad, 380051, India. .
Rao P; Department of Biochemistry and Forensic Science, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India.
Prajapati J; Department of Biochemistry and Forensic Science, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India.
Rawal RM; Department of Biochemistry and Forensic Science, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India.; Department of Life Science, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India.
Goswami D; Department of Microbiology and Biotechnology, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 02; Vol. 14 (1), pp. 49. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:: Journal Article
MeSH Terms:: Molecular Dynamics Simulation*
Indoles*/pharmacology
Glycogen Synthase Kinase 3 beta ; Workflow ; Molecular Docking Simulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 33.

Tytuł:: A Phase II Trial of Nintedanib in Patients with Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma: In-Depth Analysis of Nintedanib Arm from the KCSG HN 15-16 TRIUMPH Trial.
Autorzy:: Kim KH; Divison of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Lim SM; Divison of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Ahn HK; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Lee YG; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee KW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Ahn MJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Keam B; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Kim HR; Divison of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Lee HW; Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea.
An HJ; Division of Medical Oncology, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Kim JS; Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea.; Pokaż więcej
Źródło:: Cancer research and treatment [Cancer Res Treat] 2024 Jan; Vol. 56 (1), pp. 37-47. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:: Clinical Trial, Phase II; Multicenter Study; Journal Article
MeSH Terms:: Neoplasm Recurrence, Local*/drug therapy
Neoplasm Recurrence, Local*/genetics
Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/genetics
Indoles*
Humans ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Precision Medicine ; Antineoplastic Combined Chemotherapy Protocols

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 34.

Tytuł:: No drug-drug interactions between selective prolyl-tRNA synthetase inhibitor, bersiporocin, and pirfenidone or nintedanib in healthy participants.
Autorzy:: Shin W; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.
Park MY; Clinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Kim J; Clinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Kim J; Clinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Nam JH; Clinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Choi J; Clinical Development Center, Daewoong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Yang AY; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.
Yoo H; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.
Lee YS; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.
Kim A; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.; Institute for Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam-si, Gyeonggi-do, Republic of Korea.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13701.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 CYP2D6*
Idiopathic Pulmonary Fibrosis*/chemically induced
Idiopathic Pulmonary Fibrosis*/drug therapy
Indoles*
Humans ; Healthy Volunteers ; Treatment Outcome ; Pyridones ; Drug Interactions ; Tablets/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 35.

Tytuł:: Novel N -methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardio vascular risks.
Autorzy:: Philoppes JN; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Abourehab MAS; Department of Pharmaceutics, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Sebak M; Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
A Darwish M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
Lamie PF; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 246-266.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Indoles*/pharmacology
Protective Agents*/pharmacology
Cyclooxygenase 2 ; Stomach ; Animals ; Anti-Bacterial Agents/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 36.

Tytuł:: The study of tryptophol containing emulgel on fungal reduction and skin irritation.
Autorzy:: Kitisin T; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Muangkaew W; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Thitipramote N; School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.
Pudgerd A; Division of Anatomy, School of Medical Science, University of Phayao, Muang, Phayao, Thailand.
Sukphopetch P; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Nov 02; Vol. 13 (1), pp. 18881. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Skin*
Indoles*
Mice ; Animals ; Humans ; Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Administration, Topical

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 37.

Tytuł:: Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles' biosynthetic logic.
Autorzy:: Liu C; Department Chinese Medicine Authentication, College of Pharmacy, Naval Medical University (Second Military Medical University), Shanghai, China.; Department of Pharmacy, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Cheng M; Department Chinese Medicine Authentication, College of Pharmacy, Naval Medical University (Second Military Medical University), Shanghai, China.; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Ma C; Department of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chen J; Department Chinese Medicine Authentication, College of Pharmacy, Naval Medical University (Second Military Medical University), Shanghai, China.
Tan H; Department Chinese Medicine Authentication, College of Pharmacy, Naval Medical University (Second Military Medical University), Shanghai, China. .; Department of Pharmacy, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. .; Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, China. .; Pokaż więcej
Źródło:: BMC plant biology [BMC Plant Biol] 2023 Oct 31; Vol. 23 (1), pp. 527. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Indoles*/metabolism
Drugs, Chinese Herbal*/metabolism
Plants ; Plant Leaves/genetics ; Plant Leaves/metabolism ; Organic Chemicals/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 38.

Tytuł:: A real-world disproportionality analysis of Rucaparib: Post-marketing Pharmacovigilance Data.
Autorzy:: Zhang Q; Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Ding Y; Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, 113-0033, Japan.
Shu Y; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Avenue, Wuhan, 430030, China. .
Chen J; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Avenue, Wuhan, 430030, China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2023 Aug 11; Vol. 23 (1), pp. 745. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:: Journal Article
MeSH Terms:: Pharmacovigilance*
Indoles*/adverse effects
Adult ; Female ; United States ; Humans ; Databases, Factual ; United States Food and Drug Administration

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 39.

Tytuł:: Purification of Natural Pigments Violacein and Deoxyviolacein Produced by Fermentation Using Yarrowia lipolytica .
Autorzy:: Nemer G; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu-CS 60319, 60203 Compiègne CEDEX, France.; Laboratoire CTA, UR TVA, Centre d'Analyses et de Recherche, Faculté des Sciences, Université Saint-Joseph, Beyrouth 1104 2020, Lebanon.
Louka N; Laboratoire CTA, UR TVA, Centre d'Analyses et de Recherche, Faculté des Sciences, Université Saint-Joseph, Beyrouth 1104 2020, Lebanon.
Rabiller Blandin P; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu-CS 60319, 60203 Compiègne CEDEX, France.
Maroun RG; Laboratoire CTA, UR TVA, Centre d'Analyses et de Recherche, Faculté des Sciences, Université Saint-Joseph, Beyrouth 1104 2020, Lebanon.
Vorobiev E; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu-CS 60319, 60203 Compiègne CEDEX, France.
Rossignol T; Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France.
Nicaud JM; Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France.
Guénin E; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu-CS 60319, 60203 Compiègne CEDEX, France.
Koubaa M; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu-CS 60319, 60203 Compiègne CEDEX, France.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 May 24; Vol. 28 (11). Date of Electronic Publication: 2023 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Indoles*/isolation & purification
Yarrowia*/chemistry
Yarrowia*/genetics
Yarrowia*/metabolism
Pigments, Biological*/biosynthesis
Pigments, Biological*/genetics
Pigments, Biological*/isolation & purification
Fermentation ; Biotechnology ; Genetic Engineering

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 40.

Tytuł:: Indole-3-Propionic Acid, a Gut Microbiota-Derived Tryptophan Metabolite, Promotes Endothelial Dysfunction Impairing Purinergic-Induced Nitric Oxide Release in Endothelial Cells.
Autorzy:: Geddo F; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy.
Antoniotti S; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy.
Gallo MP; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy.
Querio G; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: Gastrointestinal Microbiome*
Vascular Diseases*/metabolism
Propionates*
Animals ; Cattle ; Endothelial Cells/metabolism ; Nitric Oxide/metabolism ; Tryptophan/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Indoles/pharmacology ; Indoles/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Indoles"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język