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Wyszukujesz frazę ""Induced Pluripotent Stem Cells"" wg kryterium: Temat


Tytuł :
iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II.
Autorzy :
Hong J; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA; Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Cheng YS; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Yang S; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Swaroop M; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Xu M; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Beers J; iPSC Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Zou J; iPSC Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Huang W; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Marugan JJ; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
Cai X; Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. Electronic address: .
Zheng W; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2022 Mar 01; Vol. 412 (1), pp. 113007. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Induced Pluripotent Stem Cells/*drug effects
Induced Pluripotent Stem Cells/*metabolism
Mucopolysaccharidosis II/*drug therapy
Mucopolysaccharidosis II/*metabolism
Neural Stem Cells/*drug effects
Neural Stem Cells/*metabolism
2-Hydroxypropyl-beta-cyclodextrin/therapeutic use ; Cell Line ; Enzyme Replacement Therapy ; Glycosaminoglycans/metabolism ; Humans ; Iduronate Sulfatase/therapeutic use ; Induced Pluripotent Stem Cells/pathology ; Lipid Metabolism/drug effects ; Models, Neurological ; Mucopolysaccharidosis II/pathology ; Neural Stem Cells/pathology ; Phenotype ; Recombinant Proteins/therapeutic use ; Tocopherols/therapeutic use
Czasopismo naukowe
Tytuł :
Glycosaminoglycans promote osteogenesis from human induced pluripotent stem cells via neural crest induction.
Autorzy :
Yanagisawa T; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan; DHC Corporation Life Science Division, Minato-ku, Tokyo, Japan.
Ouchi T; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan; Department of Dentistry and Oral Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan; Department of Physiology, Tokyo Dental College, Chiyoda-ku, Tokyo, Japan.
Shibata S; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan; Division of Microscopic Anatomy, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Negishi T; DHC Corporation Life Science Division, Minato-ku, Tokyo, Japan.
Okano H; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 May 07; Vol. 603, pp. 49-56. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Induced Pluripotent Stem Cells*
Osteogenesis*
Cell Differentiation ; Cells, Cultured ; Glucosamine/metabolism ; Glucosamine/pharmacology ; Glycosaminoglycans/metabolism ; Humans ; Neural Crest ; Osteoblasts/metabolism
Czasopismo naukowe
Tytuł :
Epicardial injection of allogeneic human-induced-pluripotent stem cell-derived cardiomyocytes in patients with advanced heart failure: protocol for a phase I/IIa dose-escalation clinical trial.
Autorzy :
Zhang H; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing, China.
Xue Y; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Pan T; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing, China.
Zhu X; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Chong H; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Xu C; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Fan F; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Cao H; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Zhang B; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Pan J; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Zhou Q; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China.
Yang G; HELP Therapeutics, Nanjing, Jiangsu, China.
Wang J; HELP Therapeutics, Nanjing, Jiangsu, China .
Wang DJ; Department of Cardiothoracic Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China .; Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing, China.
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Źródło :
BMJ open [BMJ Open] 2022 May 06; Vol. 12 (5), pp. e056264. Date of Electronic Publication: 2022 May 06.
Typ publikacji :
Journal Article
MeSH Terms :
Heart Failure*/surgery
Hematopoietic Stem Cell Transplantation*
Induced Pluripotent Stem Cells*/pathology
Induced Pluripotent Stem Cells*/transplantation
Animals ; Coronary Artery Bypass ; Humans ; Mammals ; Myocytes, Cardiac/pathology
Czasopismo naukowe
Tytuł :
Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells.
Autorzy :
Estrada HQ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Patel S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Rabizadeh S; Division of Pediatric Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA, USAand.
Casero D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Barrett RJ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
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Źródło :
Inflammatory bowel diseases [Inflamm Bowel Dis] 2022 May 04; Vol. 28 (5), pp. 667-679.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*/metabolism
Organoids*/metabolism
Fibrosis ; Humans ; Intestines ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Disheveled binding antagonist of β-catenin 1 interacted with β-catenin and connexin 43 in human-induced pluripotent stem cells-derived cardiomyocytes.
Autorzy :
Hou J; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Huang S; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Long Y; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Feng K; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shang L; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Zhou Z; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Yue Y; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Huang X; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Chen G; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Wu Z; Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Nhc Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
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Źródło :
Bioengineered [Bioengineered] 2022 May; Vol. 13 (5), pp. 11594-11601.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*/metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Cell Differentiation ; Connexin 43/genetics ; Connexin 43/metabolism ; Humans ; Myocytes, Cardiac/metabolism ; Nuclear Proteins/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Cardiac Cell Therapy with Pluripotent Stem Cell-Derived Cardiomyocytes: What Has Been Done and What Remains to Do?
Autorzy :
Selvakumar D; Centre for Heart Research, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, Australia.
Reyes L; Centre for Heart Research, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia.
Chong JJH; Centre for Heart Research, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia. .; Department of Cardiology, Westmead Hospital, Westmead, NSW, Australia. .
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Źródło :
Current cardiology reports [Curr Cardiol Rep] 2022 May; Vol. 24 (5), pp. 445-461. Date of Electronic Publication: 2022 Mar 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Induced Pluripotent Stem Cells*
Pluripotent Stem Cells*
Cell Differentiation ; Cell- and Tissue-Based Therapy ; Humans ; Myocardium ; Myocytes, Cardiac
Czasopismo naukowe
Tytuł :
Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury.
Autorzy :
Shibata R; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Nagoshi N; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Kajikawa K; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Ito S; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Shibata S; Electron Microscope Laboratory, Keio University School of Medicine, Tokyo, Japan.; Division of Microscopic Anatomy, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Shindo T; Electron Microscope Laboratory, Keio University School of Medicine, Tokyo, Japan.
Khazaei M; Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Nori S; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Kohyama J; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Fehlings MG; Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Matsumoto M; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Nakamura M; Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Okano H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
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Źródło :
Journal of neurotrauma [J Neurotrauma] 2022 May; Vol. 39 (9-10), pp. 667-682.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Spinal Cord Injuries*
Animals ; Cell Differentiation/physiology ; Humans ; Mice ; Receptor, Anaphylatoxin C5a ; Recovery of Function/physiology ; Spinal Cord ; Stem Cell Transplantation/methods
Czasopismo naukowe
Tytuł :
Tau talk - synaptic and mitochondrial proteins interact with Tau in human neurons.
Autorzy :
King D; UK Dementia Research Institute, The University of Edinburgh, Edinburgh, UK; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. Electronic address: .
Spires-Jones TL; UK Dementia Research Institute, The University of Edinburgh, Edinburgh, UK; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
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Źródło :
Trends in neurosciences [Trends Neurosci] 2022 May; Vol. 45 (5), pp. 339-341. Date of Electronic Publication: 2022 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/pathology
Mitochondrial Proteins*/metabolism
Brain/metabolism ; Humans ; Neurons/metabolism ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
'Channeling' therapeutic discovery for epileptic encephalopathy through iPSC technologies.
Autorzy :
Simkin D; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Ambrosi C; Q-State Biosciences, Inc., Cambridge, MA 02139, USA.
Marshall KA; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Williams LA; Q-State Biosciences, Inc., Cambridge, MA 02139, USA.
Eisenberg J; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Gharib M; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Dempsey GT; Q-State Biosciences, Inc., Cambridge, MA 02139, USA.
George AL Jr; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
McManus OB; Q-State Biosciences, Inc., Cambridge, MA 02139, USA. Electronic address: .
Kiskinis E; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: .
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Źródło :
Trends in pharmacological sciences [Trends Pharmacol Sci] 2022 May; Vol. 43 (5), pp. 392-405.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Channelopathies*
Epilepsy*/genetics
Epilepsy*/therapy
Induced Pluripotent Stem Cells*
Child ; Humans ; Mutation ; Neurons
Czasopismo naukowe
Tytuł :
Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants.
Autorzy :
Manhas A; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Jahng JWS; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Vera CD; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Shenoy SP; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Knowles JW; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Wu JC; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA. Electronic address: .
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Źródło :
Stem cell research [Stem Cell Res] 2022 May; Vol. 61, pp. 102774. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiomyopathy, Hypertrophic*/pathology
Induced Pluripotent Stem Cells*/metabolism
AMP-Activated Protein Kinases/genetics ; Cytoskeletal Proteins/genetics ; Heterozygote ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
Human iPS cell-derived cartilaginous tissue spatially and functionally replaces nucleus pulposus.
Autorzy :
Kamatani T; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan; Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hagizawa H; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan; Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Tissue Biochemistry, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yarimitsu S; Department of Mechanical Systems Engineering, Faculty of Systems Design, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo, 192-0397, Japan.
Morioka M; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan; Department of Tissue Biochemistry, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Koyamatsu S; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan; Department of Tissue Biochemistry, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Sugimoto M; Technology and Development Team for Mammalian Genome Dynamics, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Kodama J; Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yamane J; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Ishiguro H; Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Shichino S; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute of Biomedical Sciences, Tokyo University of Science, Building 17 Second Floor, 2641, Yamasaki, Noda, Chiba, 278-0042, Japan.
Abe K; Technology and Development Team for Mammalian Genome Dynamics, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Fujibuchi W; Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Fujie H; Department of Mechanical Systems Engineering, Faculty of Systems Design, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo, 192-0397, Japan.
Kaito T; Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tsumaki N; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan; Department of Tissue Biochemistry, Graduate School of Medicine and Frontier Biosciences, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2022 May; Vol. 284, pp. 121491. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Intervertebral Disc*
Intervertebral Disc Degeneration*/therapy
Nucleus Pulposus*
Animals ; Cartilage ; Humans ; Rats ; Regeneration
Czasopismo naukowe
Tytuł :
Biobased Elastomer Nanofibers Guide Light-Controlled Human-iPSC-Derived Skeletal Myofibers.
Autorzy :
Cheesbrough A; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, NW3 2PF, UK.; Centre for Gene Therapy and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, Centre for Developmental Neurobiology, Kings College London, London, SE1 9RT, UK.
Sciscione F; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, NW3 2PF, UK.
Riccio F; Centre for Gene Therapy and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, Centre for Developmental Neurobiology, Kings College London, London, SE1 9RT, UK.
Harley P; Centre for Gene Therapy and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, Centre for Developmental Neurobiology, Kings College London, London, SE1 9RT, UK.
R'Bibo L; Centre for Gene Therapy and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, Centre for Developmental Neurobiology, Kings College London, London, SE1 9RT, UK.
Ziakas G; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, NW3 2PF, UK.
Darbyshire A; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, NW3 2PF, UK.
Lieberam I; Centre for Gene Therapy and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, Centre for Developmental Neurobiology, Kings College London, London, SE1 9RT, UK.
Song W; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Department of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London, NW3 2PF, UK.
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Źródło :
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2022 May; Vol. 34 (18), pp. e2110441. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Nanofibers*
Cell Differentiation ; Elastomers ; Humans ; Muscle Fibers, Skeletal ; Muscle, Skeletal ; Tissue Engineering/methods ; Tissue Scaffolds
Czasopismo naukowe
Tytuł :
A defined human-specific platform for modeling neuronal network stimulation in vitro and in silico.
Autorzy :
Wen J; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty & University Hospital Bonn, Germany.
Peitz M; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty & University Hospital Bonn, Germany; Cell Programming Core Facility, University of Bonn Medical Faculty, Bonn, Germany.
Brüstle O; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty & University Hospital Bonn, Germany. Electronic address: .
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2022 May 01; Vol. 373, pp. 109562. Date of Electronic Publication: 2022 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*/physiology
Neurons*/physiology
Electric Stimulation ; Electrophysiological Phenomena ; Humans ; Prosencephalon
Czasopismo naukowe
Tytuł :
Deconvoluting the Cells of the Human Heart with iPSC Technology: Cell Types, Protocols, and Uses.
Autorzy :
Yu B; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94503, USA.
Zhao SR; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94503, USA.
Yan CD; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94503, USA.
Zhang M; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94503, USA.
Wu JC; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94503, USA. .; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA. .; Department of Radiology, Stanford University, Stanford, CA, USA. .; 265 Campus Drive G1120B, Stanford, CA, 94305, USA. .
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Źródło :
Current cardiology reports [Curr Cardiol Rep] 2022 May; Vol. 24 (5), pp. 487-496. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiovascular Diseases*/metabolism
Cardiovascular Diseases*/therapy
Induced Pluripotent Stem Cells*
Cell Differentiation/physiology ; Endothelial Cells ; Humans ; Myocytes, Cardiac
Czasopismo naukowe
Tytuł :
Therapeutic function of iPSCs-derived primitive neuroepithelial cells in a rat model of Parkinson's disease.
Autorzy :
Guo Y; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China.
Guan Y; University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.
Zhu H; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China.
Sun T; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China.
Wang Y; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China.
Huang Y; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China.
Ma C; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China; Institute of Beijing Animal Science and Veterinary, Chinese Academy of Agricultural Science, Beijing, 100193, China.
Emery R; Department of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030, USA.
Guan W; Institute of Beijing Animal Science and Veterinary, Chinese Academy of Agricultural Science, Beijing, 100193, China.
Wang C; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China. Electronic address: .
Liu C; School of Laboratory Medicine, School of Life Sciences, Bengbu Medical College, Bengbu, 233000, China; Department of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030, USA. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2022 May; Vol. 155, pp. 105324. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Induced Pluripotent Stem Cells*
Parkinson Disease*/therapy
Animals ; Cell Differentiation/physiology ; Disease Models, Animal ; Dopaminergic Neurons ; Neuroepithelial Cells/transplantation ; Oxidopamine/toxicity ; Rats ; Substantia Nigra
Czasopismo naukowe
Tytuł :
Substrate stiffness regulates differentiation of induced pluripotent stem cells into heart valve endothelial cells.
Autorzy :
Cao H; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhou Q; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Liu C; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhang Y; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Xie M; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Qiao W; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
Dong N; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2022 Apr 15; Vol. 143, pp. 115-126. Date of Electronic Publication: 2022 Feb 27.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Cell Differentiation/genetics ; Endothelial Cells ; Heart Valves ; Humans ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies.
Autorzy :
Rossbach B; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.; Fraunhofer Institute for Biomedical Engineering (IBMT), Fraunhofer-Forum Berlin, 10178 Berlin, Germany.
Hariharan K; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.; Fraunhofer Institute for Biomedical Engineering (IBMT), Fraunhofer Project Center for Stem Cell Processing, 97082 Würzburg, Germany.
Mah N; Fraunhofer Institute for Biomedical Engineering (IBMT), Fraunhofer-Forum Berlin, 10178 Berlin, Germany.
Oh SJ; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.
Volk HD; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.; Institute for Medical Immunology (IMI), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.
Reinke P; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCat), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.
Kurtz A; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.; Fraunhofer Institute for Biomedical Engineering (IBMT), Fraunhofer-Forum Berlin, 10178 Berlin, Germany.
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Źródło :
Cells [Cells] 2022 Apr 13; Vol. 11 (8). Date of Electronic Publication: 2022 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Induced Pluripotent Stem Cells*
Cell Differentiation ; Cell- and Tissue-Based Therapy ; Humans ; Killer Cells, Natural ; Lymphocyte Activation
Czasopismo naukowe
Tytuł :
Deciphering Cardiac Biology and Disease by Single-Cell Transcriptomic Profiling.
Autorzy :
Wang L; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Hu S; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Zhou B; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
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Źródło :
Biomolecules [Biomolecules] 2022 Apr 12; Vol. 12 (4). Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Induced Pluripotent Stem Cells*
Biology ; Cell Differentiation/genetics ; Myocytes, Cardiac/physiology ; Transcriptome
Czasopismo naukowe
Tytuł :
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Autorzy :
Deng L; Department of Periodontology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Yi S; Department of Periodontology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Yin X; Department of First Clinical Division, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China.
Li Y; Department of Cell Biology, School of Basic Medical Sciences, Peking University Stem Cell Research Center, Peking University, Beijing, 100191, People's Republic of China. .
Luan Q; Department of Periodontology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, People's Republic of China. .
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Źródło :
Stem cell research & therapy [Stem Cell Res Ther] 2022 Apr 12; Vol. 13 (1), pp. 162. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
GTP Phosphohydrolases*/genetics
GTP Phosphohydrolases*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Mesenchymal Stem Cells*/metabolism
Mitochondrial Proteins*/genetics
Mitochondrial Proteins*/metabolism
Cell Differentiation/genetics ; Cells, Cultured ; Female ; Glycolysis/genetics ; Humans ; Osteogenesis ; Pregnancy ; Wnt Signaling Pathway/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Generation of SIV-resistant T cells and macrophages from nonhuman primate induced pluripotent stem cells with edited CCR5 locus.
Autorzy :
D'Souza SS; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Kumar A; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Weinfurter J; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA.
Park MA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Maufort J; Morgridge Institute for Research, Madison, USA.
Tao L; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Kang H; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Dettle ST; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Golos T; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI 53706 USA; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI 53705 USA.
Thomson JA; Morgridge Institute for Research, Madison, USA; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.
Reynolds MR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA.
Slukvin I; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53792, USA. Electronic address: .
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Źródło :
Stem cell reports [Stem Cell Reports] 2022 Apr 12; Vol. 17 (4), pp. 953-963. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Acquired Immunodeficiency Syndrome*
Induced Pluripotent Stem Cells*
Animals ; CD8-Positive T-Lymphocytes ; Macaca fascicularis ; Macrophages ; Receptors, CCR5/genetics
Czasopismo naukowe

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