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Tytuł:
Omics Studies of Tumor Cells under Microgravity Conditions.
Autorzy:
Graf J; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Corydon TJ; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, 8200 Aarhus N, Denmark.
Sahana J; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Abdelfattah F; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.
Wuest SL; Space Biology Group, Institute of Medical Engineering, Lucerne University of Applied Sciences and Arts, 6052 Hergiswil, Switzerland.
Egli M; Space Biology Group, Institute of Medical Engineering, Lucerne University of Applied Sciences and Arts, 6052 Hergiswil, Switzerland.; National Center for Biomedical Research in Space, Innovation Cluster Space and Aviation (UZH Space Hub), University Zurich, 8006 Zurich, Switzerland.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Kraus A; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, 39120 Magdeburg, Germany.
Wise PM; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
Infanger M; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, 39120 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 11; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Weightlessness*
Sarcoma*
Lung Neoplasms*
Humans ; Male ; Female ; Proteomics ; Cytoskeleton
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Current Knowledge about the Impact of Microgravity on Gene Regulation.
Autorzy:
Corydon TJ; Department of Biomedicine, Aarhus University, Hoegh Guldbergs Gade 10, 8000 Aarhus, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus, Denmark.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Richter P; Gravitational Biology Group, Department of Biology, Friedrich-Alexander University, 91058 Erlangen, Germany.
Strauch SM; Postgraduate Program in Health and Environment, University of Joinville Region, Joinville 89219-710, SC, Brazil.
Böhmer M; Institute for Molecular Biosciences, Johann Wolfgang Goethe Universität, 60438 Frankfurt am Main, Germany.
Ricciardi DA; Institute for Molecular Biosciences, Johann Wolfgang Goethe Universität, 60438 Frankfurt am Main, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Erzinger GS; Postgraduate Program in Health and Environment, University of Joinville Region, Joinville 89219-710, SC, Brazil.
Lebert M; Gravitational Biology Group, Department of Biology, Friedrich-Alexander University, 91058 Erlangen, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Wise PM; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
Grimm D; Department of Biomedicine, Aarhus University, Hoegh Guldbergs Gade 10, 8000 Aarhus, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
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Źródło:
Cells [Cells] 2023 Mar 29; Vol. 12 (7). Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Weightlessness*
Space Flight*
MicroRNAs*/genetics
Animals ; Humans ; Gene Expression Regulation ; Cell Differentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cabozantinib, Vandetanib, Pralsetinib and Selpercatinib as Treatment for Progressed Medullary Thyroid Cancer with a Main Focus on Hypertension as Adverse Effect.
Autorzy:
Højer Wang L; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Wise PM; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Grimm D; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Kreissl MC; Department of Radiology and Nuclear Medicine, Division of Nuclear Medicine, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 24; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Neuroendocrine*/drug therapy
Carcinoma, Neuroendocrine*/pathology
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/pathology
Hypertension*/drug therapy
Hypertension*/chemically induced
Humans ; Protein Kinase Inhibitors/adverse effects ; Piperidines/adverse effects
SCR Disease Name:
Thyroid cancer, medullary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prolonged Exposure to Simulated Microgravity Changes Release of Small Extracellular Vesicle in Breast Cancer Cells.
Autorzy:
Wise PM; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Sahana J; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.
Neviani P; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
Corydon TJ; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University Clinic, Leipziger Str. 44, 39120 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University Clinic, Leipziger Str. 44, 39120 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University Clinic, Leipziger Str. 44, 39120 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University Clinic, Leipziger Str. 44, 39120 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 17; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 17.
Typ publikacji:
Journal Article
MeSH Terms:
Weightlessness*
Breast Neoplasms*
Space Flight*
Extracellular Vesicles*
Humans ; Female ; Quality of Life ; Weightlessness Simulation ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microgravity-Related Changes in Bone Density and Treatment Options: A Systematic Review.
Autorzy:
Baran R; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Heer M; IU International University of Applied Sciences, 99084 Erfurt, Germany.; Institute of Nutrition and Food Sciences, Nutritional Physiology, University of Bonn, 53115 Bonn, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Grimm D; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 03; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Bone Diseases, Metabolic*
Bone Resorption*
Space Flight*
Weightlessness*/adverse effects
Bone Density ; Bone and Bones ; Humans ; Receptor Activator of Nuclear Factor-kappa B
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
In Prostate Cancer Cells Cytokines Are Early Responders to Gravitational Changes Occurring in Parabolic Flights.
Autorzy:
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Dietrichs D; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Corydon TJ; Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus, Denmark.
Hemmersbach R; Gravitational Biology, Institute of Aerospace Medicine, German Aerospace Center, Linder Höhe, 51147 Cologne, Germany.
Liemersdorf C; Gravitational Biology, Institute of Aerospace Medicine, German Aerospace Center, Linder Höhe, 51147 Cologne, Germany.
Melnik D; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Hübner N; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 10785 Berlin, Germany.; Charité-Universitätsmedizin, 10117 Berlin, Germany.
Saar K; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 17; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
Prostatic Neoplasms*/genetics
Space Flight*
Weightlessness*
Carcinogenesis ; Cytokines/genetics ; Humans ; Interleukin-6 ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model.
Autorzy:
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Cortés-Sánchez JL; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Egli M; Space Biology Group, Institute of Medical Engineering, Lucerne University of Applied Sciences and Arts, 6002 Hergiswil, Switzerland.
Kraus A; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Sahana J; Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Corydon TJ; Department of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus, Denmark.
Hemmersbach R; Gravitational Biology, Institute of Aerospace Medicine, German Aerospace Center, Linder Höhe, 51147 Cologne, Germany.
Wise PM; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 12; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*
Weightlessness*
Humans ; Male ; Organoids ; Spheroids, Cellular ; Weightlessness Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space.
Autorzy:
Wise PM; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.
Neviani P; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.
Riwaldt S; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Corydon TJ; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, 8200 Aarhus N, Denmark.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Braun M; Deutsches Zentrum für Luft- und Raumfahrt (DLR), Raumfahrtagentur im DLR, Bonn-Oberkassel, 53227 Bonn, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 27; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Extraterrestrial Environment*
Weightlessness*
Exosomes/*genetics
MicroRNAs/*metabolism
Thyroid Neoplasms/*genetics
Cell Line, Tumor ; Exosomes/metabolism ; Humans ; MicroRNAs/genetics ; Thyroid Neoplasms/metabolism ; Thyroid Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Kinase-Inhibitors in Iodine-Refractory Differentiated Thyroid Cancer-Focus on Occurrence, Mechanisms, and Management of Treatment-Related Hypertension.
Autorzy:
Kaae AC; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Kreissl MC; Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Grimm D; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 12; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hypertension*/chemically induced
Hypertension*/physiopathology
Hypertension*/therapy
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/physiopathology
Antineoplastic Agents/*therapeutic use
Iodine Radioisotopes/*therapeutic use
Protein Kinase Inhibitors/*therapeutic use
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The CellBox-2 Mission to the International Space Station: Thyroid Cancer Cells in Space.
Autorzy:
Melnik D; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Schulz H; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Kopp S; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Bauer J; SiHaTho GmbH, Pferdsbach 4a, 35216 Biedenkopf, Germany.
Baselet B; SCK CEN, Belgian Nuclear Research Centre, Boeretang 200, 2400 Mol, Belgium.
Vermeesen R; SCK CEN, Belgian Nuclear Research Centre, Boeretang 200, 2400 Mol, Belgium.
Baatout S; SCK CEN, Belgian Nuclear Research Centre, Boeretang 200, 2400 Mol, Belgium.; Department Molecular Biotechnology, Gent University, 9000 Gent, Belgium.
Corydon TJ; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 167, 8200 Aarhus, Denmark.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt-und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 16; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Transcriptome*
Weightlessness*
Adenocarcinoma, Follicular/*pathology
Biomarkers, Tumor/*metabolism
Proteome/*metabolism
Spheroids, Cellular/*pathology
Thyroid Neoplasms/*pathology
Adenocarcinoma, Follicular/genetics ; Adenocarcinoma, Follicular/metabolism ; Biomarkers, Tumor/genetics ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Proteome/analysis ; Space Flight ; Spheroids, Cellular/metabolism ; Thyroid Neoplasms/genetics ; Thyroid Neoplasms/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
SARS-CoV-2 and hypertension.
Autorzy:
Ravichandran B; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Grimm D; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Kopp S; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, University Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
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Źródło:
Physiological reports [Physiol Rep] 2021 Jun; Vol. 9 (11), pp. e14800.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Angiotensin-Converting Enzyme Inhibitors/*therapeutic use
COVID-19/*physiopathology
Hypertension/*virology
Renin-Angiotensin System/*physiology
COVID-19/epidemiology ; COVID-19/virology ; Humans ; Hypertension/physiopathology ; Pandemics ; Risk Factors ; SARS-CoV-2/isolation & purification
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Effect of Continuous Positive Airway Pressure Therapy on Obstructive Sleep Apnea-Related Hypertension.
Autorzy:
Baran R; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Grimm D; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.; Department for Microgravity Research and Translational Regenerative Medicine, Otto-von-Guericke University, D-39106 Magdeburg, Germany.
Infanger M; Department for Microgravity Research and Translational Regenerative Medicine, Otto-von-Guericke University, D-39106 Magdeburg, Germany.
Wehland M; Department for Microgravity Research and Translational Regenerative Medicine, Otto-von-Guericke University, D-39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 25; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Continuous Positive Airway Pressure/*adverse effects
Hypertension/*complications
Sleep Apnea, Obstructive/*therapy
Adult ; Aged ; Aged, 80 and over ; Antihypertensive Agents/pharmacology ; Female ; Humans ; Hypertension/drug therapy ; Hypertension/physiopathology ; Male ; Middle Aged ; Risk Factors ; Sleep Apnea, Obstructive/complications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space.
Autorzy:
Wise PM; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
Neviani P; The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.
Riwaldt S; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Corydon TJ; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Braun M; Deutsches Zentrum für Luft- und Raumfahrt (DLR), Raumfahrtmanagement Bonn-Oberkassel, 53227 Bonn, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 21; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Space Flight*
Weightlessness*
Exosomes/*metabolism
Thyroid Neoplasms/*metabolism
Antigens, CD/metabolism ; Cell Line, Tumor ; Fluorescence ; Humans ; Interferometry ; Particle Size
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Tissue Engineering of Cartilage Using a Random Positioning Machine.
Autorzy:
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Steinwerth P; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Aleshcheva G; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Sahana J; Department for Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Hemmersbach R; Gravitational Biology, Institute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany.
Lützenberg R; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Kopp S; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Department for Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 16; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage/*cytology
Tissue Engineering/*methods
Weightlessness Simulation/*instrumentation
Cartilage/metabolism ; Cells, Cultured ; Chondrocytes/cytology ; Chondrocytes/metabolism ; Collagen/genetics ; Collagen/metabolism ; Core Binding Factor alpha Subunits/genetics ; Core Binding Factor alpha Subunits/metabolism ; Culture Media/chemistry ; Humans ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/metabolism ; SOX Transcription Factors ; Spheroids, Cellular/cytology ; Spheroids, Cellular/metabolism ; Tissue Engineering/instrumentation ; Vimentin/genetics ; Vimentin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of Microgravity on Apoptosis in Cells, Tissues, and Other Systems In Vivo and In Vitro.
Autorzy:
Prasad B; Gravitational Biology Group, Department of Biology, Friedrich-Alexander University, Staudtstraße 5, 91058 Erlangen, Germany.
Grimm D; Department of Biomedicine, Aarhus University, Høegh-Guldbergsgade 10, 8000 Aarhus C, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Strauch SM; Postgraduate Program in Health and Environment, University of Joinville Region, Rua Paulo Malschitzki, 10 - Zona Industrial Norte, Joinville, SC 89219-710, Brazil.
Erzinger GS; Postgraduate Program in Health and Environment, University of Joinville Region, Rua Paulo Malschitzki, 10 - Zona Industrial Norte, Joinville, SC 89219-710, Brazil.
Corydon TJ; Department of Biomedicine, Aarhus University, Høegh-Guldbergsgade 10, 8000 Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Palle Juul-Jensens Blvd. 99, 8200 Aarhus N, Denmark.
Lebert M; Gravitational Biology Group, Department of Biology, Friedrich-Alexander University, Staudtstraße 5, 91058 Erlangen, Germany.; Space Biology Unlimited SAS, 24 Cours de l'Intendance, 33000 Bordeaux, France.
Magnusson NE; Diabetes and Hormone Diseases, Medical Research Laboratory, Department of Clinical Medicine, Faculty of Health, Aarhus University, Palle Juul-Jensens Boulevard 165, 8200 Aarhus N, Denmark.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Richter P; Gravitational Biology Group, Department of Biology, Friedrich-Alexander University, Staudtstraße 5, 91058 Erlangen, Germany.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 09; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis*
Weightlessness/*adverse effects
Animals ; Cosmic Radiation/adverse effects ; Humans ; Space Flight/standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Breast Cancer Cells in Microgravity: New Aspects for Cancer Research.
Autorzy:
Nassef MZ; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Melnik D; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Kopp S; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Sahana J; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Infanger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Lützenberg R; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Relja B; Experimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Wehland M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
Grimm D; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Krüger M; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.; Research Group 'Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen' (MARS), Otto von Guericke University, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 05; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Weightlessness*
Breast Neoplasms/*therapy
Cell Movement/*radiation effects
Cell Proliferation/*radiation effects
Breast Neoplasms/pathology ; Cell Survival/radiation effects ; Female ; Humans ; Spheroids, Cellular/radiation effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A case of upper lip necrosis after cosmetic injection of hyaluronic acid soft-tissue filler-Does capillary infarction play a role in the development of vascular compromise, and what are the implications?
Autorzy:
Hirsch P; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Infanger M; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Kraus A; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2020 Jun; Vol. 19 (6), pp. 1316-1320. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji:
Case Reports; Journal Article; Review
MeSH Terms:
Cosmetic Techniques/*adverse effects
Hyaluronic Acid/*adverse effects
Infarction/*chemically induced
Lip/*blood supply
Skin/*blood supply
Female ; Humans ; Hyaluronic Acid/administration & dosage ; Hyaluronoglucosaminidase/administration & dosage ; Infarction/diagnosis ; Infarction/prevention & control ; Infarction/therapy ; Injections, Subcutaneous/adverse effects ; Lip/drug effects ; Lip/innervation ; Mouth Mucosa/surgery ; Nerve Block ; Skin/drug effects ; Skin Aging ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alteration of Cytoskeleton Morphology and Gene Expression in Human Breast Cancer Cells under Simulated Microgravity.
Autorzy:
Strube F; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Infanger M; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Wehland M; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Delvinioti X; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Romswinkel A; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Dietz C; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.
Kraus A; Department of Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University, Magdeburg, Germany.Electronic Address:.
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Źródło:
Cell journal [Cell J] 2020 Apr; Vol. 22 (1), pp. 106-114. Date of Electronic Publication: 2019 Sep 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy.
Autorzy:
Enevoldsen FC; Department of Biomedicine, Aarhus University, Høegh-Guldbergsgade 10, 8000 Aarhus C, Denmark.
Sahana J; Department of Biomedicine, Aarhus University, Høegh-Guldbergsgade 10, 8000 Aarhus C, Denmark.
Wehland M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Grimm D; Department of Biomedicine, Aarhus University, Høegh-Guldbergsgade 10, 8000 Aarhus C, Denmark.; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Infanger M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
Krüger M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Mar 18; Vol. 9 (3). Date of Electronic Publication: 2020 Mar 18.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insight in Adhesion Protein Sialylation and Microgravity Dependent Cell Adhesion-An Omics Network Approach.
Autorzy:
Bauer TJ; Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University Magdeburg, D-39120 Magdeburg, Germany.
Gombocz E; Melissa Informatics, 2550 Ninth Street, Suite 114, Berkeley, CA 94710, USA.
Wehland M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University Magdeburg, D-39120 Magdeburg, Germany.
Bauer J; Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.
Infanger M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University Magdeburg, D-39120 Magdeburg, Germany.
Grimm D; Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke-University Magdeburg, D-39120 Magdeburg, Germany.; Department of Biomedicine, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, Pfälzer Platz, 39106 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 04; Vol. 21 (5). Date of Electronic Publication: 2020 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Adhesion*
Protein Processing, Post-Translational*
Weightlessness*
Animals ; Cadherins/metabolism ; Cell Line, Tumor ; Cell Movement ; Databases, Factual ; Extracellular Matrix/metabolism ; Humans ; Hyaluronan Receptors/metabolism ; Integrins/metabolism ; MCF-7 Cells ; Mice ; Neoplasm Metastasis ; Protein Domains ; Proteome ; Sialic Acids/chemistry
Czasopismo naukowe
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