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Wyszukujesz frazę ""Inflammation"" wg kryterium: Temat


Tytuł :
[Research progress on the mechanism of pro-inflammatory regression mediators promoting inflammation regression by regulating immune cells].
Autorzy :
Wang J; Department of Anesthesiology, Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China. Corresponding author: Xia Haifa, Email: .
Xia H
Yao S
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Źródło :
Zhonghua wei zhong bing ji jiu yi xue [Zhonghua Wei Zhong Bing Ji Jiu Yi Xue] 2020 Jul; Vol. 32 (7), pp. 873-876.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation*
Macrophages*
Humans ; Immunity, Innate ; Inflammation Mediators ; Neutrophils ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
The role of Immunity in Fabry Disease and Hypertension: A Review of a Novel Common Pathway.
Autorzy :
Del Pinto R; Division of Internal Medicine and Nephrology, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, University of L'Aquila, San Salvatore Hospital, Building Delta 6, L'Aquila, Italy. .
Ferri C; Division of Internal Medicine and Nephrology, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, University of L'Aquila, San Salvatore Hospital, Building Delta 6, L'Aquila, Italy.
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Źródło :
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension [High Blood Press Cardiovasc Prev] 2020 Dec; Vol. 27 (6), pp. 539-546. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Blood Pressure*
Immunity, Innate*/drug effects
Fabry Disease/*immunology
Hypertension/*immunology
Inflammation/*immunology
Animals ; Anti-Inflammatory Agents/therapeutic use ; Antihypertensive Agents/therapeutic use ; Antioxidants/therapeutic use ; Fabry Disease/drug therapy ; Fabry Disease/metabolism ; Fabry Disease/physiopathology ; Humans ; Hypertension/drug therapy ; Hypertension/metabolism ; Hypertension/physiopathology ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/physiopathology ; Inflammation Mediators/metabolism ; Oxidative Stress ; Renin-Angiotensin System ; Signal Transduction ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł :
Anti-inflammatory effects of sodium-glucose co-transporter 2 inhibitors on atherosclerosis.
Autorzy :
Kang Y; Department of Endocrinology and Metabolism, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 88 Jiefang Rd, Zhejiang 310009, PR China. Electronic address: .
Zhan F; Department of Endocrinology and Metabolism, Sanmen Hospital of Traditional Chinese Medicine, Sanmen, 287 Xinxing Rd, Zhejiang 317100, PR China.
He M; Department of Vascular Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 88 Jiefang Rd, Zhejiang 310009, PR China.
Liu Z; Department of Vascular Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 88 Jiefang Rd, Zhejiang 310009, PR China. Electronic address: .
Song X; Department of Endocrinology and Metabolism, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 88 Jiefang Rd, Zhejiang 310009, PR China. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2020 Oct - Nov; Vol. 133-134, pp. 106779. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Anti-Infective Agents/*therapeutic use
Arteries/*drug effects
Atherosclerosis/*drug therapy
Blood Glucose/*drug effects
Diabetes Mellitus, Type 2/*drug therapy
Inflammation/*drug therapy
Sodium-Glucose Transporter 2 Inhibitors/*therapeutic use
Animals ; Anti-Infective Agents/adverse effects ; Arteries/metabolism ; Arteries/pathology ; Atherosclerosis/diagnosis ; Atherosclerosis/metabolism ; Biomarkers/blood ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Humans ; Inflammation/diagnosis ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Plaque, Atherosclerotic ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects
Czasopismo naukowe
Tytuł :
Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE.
Autorzy :
Zhou C; Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Qin Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chen R; Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Gao F; Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhang J; Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Lu F; Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118222. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Trigonella*
ADAM17 Protein/*antagonists & inhibitors
Carrier Proteins/*antagonists & inhibitors
Inflammation Mediators/*antagonists & inhibitors
Insulin Resistance/*physiology
Obesity/*drug therapy
ADAM17 Protein/blood ; Animals ; Carrier Proteins/blood ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Inflammation/blood ; Inflammation/drug therapy ; Inflammation Mediators/blood ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/blood ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Seeds
Czasopismo naukowe
Tytuł :
COVID-19-Associated Coagulopathy and Inflammatory Response: What Do We Know Already and What Are the Knowledge Gaps?
Autorzy :
Görlinger K; From the Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; Medical Department, Tem Innovations GmbH, Munich, Germany.
Dirkmann D; From the Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Gandhi A; Clinical Department, Instrumentation Laboratory India Private Limited, New Delhi, India.
Simioni P; General Internal Medicine and Thrombotic and Haemorrhagic Diseases Units, Department of Medicine, Padova University Hospital, Padova, Italy.
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Źródło :
Anesthesia and analgesia [Anesth Analg] 2020 Nov; Vol. 131 (5), pp. 1324-1333.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Anticoagulants/*therapeutic use
Betacoronavirus/*pathogenicity
Blood Coagulation/*drug effects
Coronavirus Infections/*therapy
Inflammation/*therapy
Pneumonia, Viral/*therapy
Pulmonary Embolism/*therapy
Venous Thromboembolism/*therapy
Venous Thrombosis/*therapy
Anti-Inflammatory Agents/adverse effects ; Anticoagulants/adverse effects ; Biomarkers/blood ; Coronavirus Infections/blood ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Evidence-Based Medicine ; Fibrin Fibrinogen Degradation Products/analysis ; Hospital Mortality ; Host-Pathogen Interactions ; Humans ; Inflammation/blood ; Inflammation/mortality ; Inflammation/virology ; Inflammation Mediators/blood ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Prognosis ; Pulmonary Embolism/blood ; Pulmonary Embolism/mortality ; Pulmonary Embolism/virology ; Risk Factors ; Venous Thromboembolism/blood ; Venous Thromboembolism/mortality ; Venous Thromboembolism/virology ; Venous Thrombosis/blood ; Venous Thrombosis/mortality ; Venous Thrombosis/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Development and characterization of a mouse model of duodenogastric reflux.
Autorzy :
Ma F; Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Ma Y; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Cui L; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Zhao X; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang B; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Xue L; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wang H; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: .
Tian Y; Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118412. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Duodenogastric Reflux/*pathology
Gastric Mucosa/*pathology
Hyperplasia/*pathology
Inflammation/*pathology
Animals ; Duodenogastric Reflux/surgery ; Gastrectomy ; Gastric Mucosa/immunology ; Gastric Mucosa/metabolism ; Hyperplasia/immunology ; Hyperplasia/metabolism ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Epigallocatechin gallate suppresses inflammation in human coronary artery endothelial cells by inhibiting NF-κB.
Autorzy :
Reddy AT; Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India. Electronic address: .
Lakshmi SP; Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India.
Maruthi Prasad E; Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan.
Varadacharyulu NC; Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India.
Kodidhela LD; Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India.
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118136. Date of Electronic Publication: 2020 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Catechin/*analogs & derivatives
Coronary Vessels/*pathology
Endothelial Cells/*pathology
Inflammation/*drug therapy
Catechin/pharmacology ; Catechin/therapeutic use ; Cell Adhesion/drug effects ; Cell Membrane Permeability/drug effects ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Monocytes/drug effects ; Monocytes/pathology ; NF-kappa B/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Hyperferritinemia in critically ill COVID-19 patients - Is ferritin the product of inflammation or a pathogenic mediator?
Autorzy :
Gómez-Pastora J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Weigand M; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Kim J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Wu X; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Strayer J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Palmer AF; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States.
Zborowski M; Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, United States.
Yazer M; Department of Pathology, University of Pittsburgh, 3636 Blvd of the Allies, Pittsburgh, PA 15213, United States.
Chalmers JJ; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff Avenue, Columbus, OH 43210, United States. Electronic address: .
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Źródło :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2020 Oct; Vol. 509, pp. 249-251. Date of Electronic Publication: 2020 Jun 21.
Typ publikacji :
Letter; Review
MeSH Terms :
Betacoronavirus*
Critical Illness*/epidemiology
Coronavirus Infections/*blood
Ferritins/*blood
Inflammation Mediators/*blood
Iron Overload/*blood
Pneumonia, Viral/*blood
Biomarkers/blood ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Humans ; Inflammation/blood ; Inflammation/diagnosis ; Iron Overload/diagnosis ; Iron Overload/epidemiology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology
SCR Disease Name :
COVID-19
Recenzja
Tytuł :
[On the inflammatory origins of AMD].
Autorzy :
Roubeix C; Sorbonne Université, Inserm, CNRS, Institut de la vision, 17 rue Moreau, F-75012 Paris, France.
Sahel JA; Sorbonne Université, Inserm, CNRS, Institut de la vision, 17 rue Moreau, F-75012 Paris, France.
Guillonneau X; Sorbonne Université, Inserm, CNRS, Institut de la vision, 17 rue Moreau, F-75012 Paris, France.
Delarasse C; Sorbonne Université, Inserm, CNRS, Institut de la vision, 17 rue Moreau, F-75012 Paris, France.
Sennlaub F; Sorbonne Université, Inserm, CNRS, Institut de la vision, 17 rue Moreau, F-75012 Paris, France.
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Transliterated Title :
Sur les origines inflammatoires de la DMLA.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2020 Oct; Vol. 36 (10), pp. 886-892. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Inflammation/*complications
Macular Degeneration/*etiology
Eye/immunology ; Eye/metabolism ; Eye/pathology ; Humans ; Immune Privilege/physiology ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Inflammation Mediators/physiology ; Macular Degeneration/epidemiology ; Macular Degeneration/immunology ; Macular Degeneration/metabolism ; Risk Factors
Czasopismo naukowe
Tytuł :
Effects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trials.
Autorzy :
Hallajzadeh J; Department of Biochemistry and Nutrition, Research Center for Evidence-Based Health Management, Maragheh University of Medical Sciences, Maragheh, Iran.
Milajerdi A; Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Mobini M; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Amirani E; Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
Azizi S; Student Research Committe, Maragheh University of Medical Sciences, Maragheh, Iran.
Nikkhah E; Medicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran.
Bahadori B; Medicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran.
Sheikhsoleimani R; Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
Mirhashemi SM; Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2020 Oct; Vol. 34 (10), pp. 2586-2608. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Blood Glucose/*drug effects
Inflammation/*drug therapy
Lipids/*blood
Nigella sativa/*chemistry
Oxidative Stress/*drug effects
Plant Extracts/*therapeutic use
Biomarkers/blood ; Blood Glucose/metabolism ; Cholesterol, LDL/blood ; Dietary Supplements ; Glycated Hemoglobin A/drug effects ; Glycated Hemoglobin A/metabolism ; Humans ; Inflammation/blood ; Inflammation Mediators/blood ; Insulin Resistance/physiology ; Nigella sativa/physiology ; Plant Extracts/pharmacology ; Randomized Controlled Trials as Topic/statistics & numerical data ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Association of elevated inflammatory markers and severe COVID-19: A meta-analysis.
Autorzy :
Ji P; Department of Emergency Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhu J
Zhong Z
Li H
Pang J
Li B
Zhang J
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Nov 20; Vol. 99 (47), pp. e23315.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Betacoronavirus*
Severity of Illness Index*
Biomarkers/*blood
Coronavirus Infections/*blood
Inflammation Mediators/*blood
Pneumonia, Viral/*blood
Adult ; Aged ; Blood Sedimentation ; C-Reactive Protein/analysis ; Coronavirus Infections/mortality ; Disease Progression ; Female ; Humans ; Inflammation ; Interleukin-10/blood ; Interleukin-6/blood ; Leukocyte Count ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/mortality ; Procalcitonin/blood
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Breast Cancer Cells Induce a Pro-inflammatory Response to Mitigate Immune Mediation in a 3D Culture Model.
Autorzy :
Augustine TN; School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa .
Duarte R; Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Candy GP; Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
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Źródło :
Anticancer research [Anticancer Res] 2020 Nov; Vol. 40 (11), pp. 6179-6193.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques*
Models, Biological*
Breast Neoplasms/*pathology
Inflammation/*pathology
Cell Shape ; Female ; Humans ; Inflammation Mediators/metabolism ; MCF-7 Cells ; Principal Component Analysis ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
N-acetylcysteine modulates non-esterified fatty acid-induced pyroptosis and inflammation in granulosa cells.
Autorzy :
Wang Y; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Li C; Jiangsu Key Laboratory of Sericutural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212018, China.
Ali I; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Li L; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: .
Wang G; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
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Źródło :
Molecular immunology [Mol Immunol] 2020 Nov; Vol. 127, pp. 157-163. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcysteine/*pharmacology
Fatty Acids, Nonesterified/*toxicity
Granulosa Cells/*pathology
Inflammation/*pathology
Pyroptosis/*drug effects
Animals ; Cattle ; Cell Survival/drug effects ; Female ; Granulosa Cells/drug effects ; Inflammation Mediators/metabolism ; Ketosis/pathology ; Models, Biological ; Oxidation-Reduction/drug effects ; Oxidative Stress/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Protective Role of C3aR (C3a Anaphylatoxin Receptor) Against Atherosclerosis in Atherosclerosis-Prone Mice.
Autorzy :
Wei LL; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Ma N; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Wu KY; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Wang JX; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Diao TY; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Zhao SJ; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
Bai L; The Second Affiliated Hospital and Cardiovascular Research Center, School of Basic Medical Sciences, Health Science Center (L.B., E.L.), Xi'an Jiaotong University, China.
Liu E; The Second Affiliated Hospital and Cardiovascular Research Center, School of Basic Medical Sciences, Health Science Center (L.B., E.L.), Xi'an Jiaotong University, China.
Li ZF; National Local Joint Engineering Research Centre of Biodiagnostics and Biotherapy (Z.-F.L.), Xi'an Jiaotong University, China.
Zhou W; Peter Gorer Department of Immunobiology, School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine (W.Z.), King's College London, United Kingdom.
Chen D; Department of Inflammation Biology, School of Immunology & Microbial Sciences (D.C.), King's College London, United Kingdom.
Li K; From the Core Research Laboratory (L.-L.W., N.M., K.-Y.W., J.-X.W., T.-Y.D., S.-J.Z., K.L.), Xi'an Jiaotong University, China.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Sep; Vol. 40 (9), pp. 2070-2083. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aorta/*metabolism
Aortic Diseases/*prevention & control
Atherosclerosis/*prevention & control
Inflammation/*prevention & control
Macrophages, Peritoneal/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Aorta/immunology ; Aorta/pathology ; Aortic Diseases/immunology ; Aortic Diseases/metabolism ; Aortic Diseases/pathology ; Atherosclerosis/immunology ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cells, Cultured ; Chemokine CCL2/metabolism ; Chemotaxis ; Disease Models, Animal ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Macrophages, Peritoneal/immunology ; Macrophages, Peritoneal/pathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; NF-kappa B/metabolism ; Phenotype ; Plaque, Atherosclerotic ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, G-Protein-Coupled/deficiency ; Receptors, G-Protein-Coupled/genetics ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
EP4 signalling is essential for controlling islet inflammation by causing a shift in macrophage polarization in obesity/type 2 diabetes.
Autorzy :
Yasui-Kato M; Department of Clinical Innovative Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Patlada S; Department of Clinical Innovative Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Functional Chemistry, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto, Japan.
Yokode M; Department of Clinical Innovative Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kamei K; Department of Functional Chemistry, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto, Japan.
Minami M; Department of Functional Chemistry, Graduate School of Science and Technology, Kyoto Institute of Technology, Kyoto, Japan.
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Źródło :
Diabetes & vascular disease research [Diab Vasc Dis Res] 2020 Jul-Aug; Vol. 17 (4), pp. 1479164120945675.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Plasticity*
Diabetes Mellitus, Type 2/*metabolism
Inflammation/*metabolism
Insulin-Secreting Cells/*metabolism
Macrophages, Peritoneal/*metabolism
Obesity/*metabolism
Receptors, Prostaglandin E, EP4 Subtype/*metabolism
Animals ; Cell Line, Tumor ; Coculture Techniques ; Cytokines/metabolism ; Diabetes Mellitus, Type 2/pathology ; Disease Models, Animal ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Insulin/metabolism ; Insulin-Secreting Cells/pathology ; Macrophage Activation ; Macrophages, Peritoneal/pathology ; Mice ; Obesity/pathology ; Phenotype ; Secretory Pathway ; Signal Transduction
Czasopismo naukowe
Tytuł :
Paeoniflorin relieves LPS-induced inflammatory pain in mice by inhibiting NLRP3 inflammasome activation via transient receptor potential vanilloid 1.
Autorzy :
Yin N; Department of Anatomy, School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Gao Q; School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Tao W; School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Chen J; School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Bi J; Department of Pathogen Biology, School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Ding F; School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Wang Z; Department of Pathogen Biology, School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Jul; Vol. 108 (1), pp. 229-241. Date of Electronic Publication: 2020 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Glucosides/*therapeutic use
Inflammasomes/*antagonists & inhibitors
Inflammation/*drug therapy
Monoterpenes/*therapeutic use
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Pain/*drug therapy
TRPV Cation Channels/*metabolism
Animals ; Calcium/metabolism ; Cytokines/biosynthesis ; Edema/complications ; Edema/drug therapy ; Glucosides/pharmacology ; Inflammasomes/metabolism ; Inflammation/complications ; Inflammation Mediators/metabolism ; Lipopolysaccharides ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Mice, Inbred C57BL ; Models, Biological ; Monoterpenes/pharmacology ; NF-kappa B/genetics ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neutrophils/drug effects ; Neutrophils/pathology ; Nociception/drug effects ; Pain/complications ; Protein Kinase C/metabolism ; TRPV Cation Channels/agonists ; Transcription, Genetic/drug effects
Czasopismo naukowe
Tytuł :
Therapeutic Effects of Anti-Inflammatory N -Acylhydrazones in the Resolution of Experimental Colitis.
Autorzy :
Cordeiro N; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brasil (N.d.M.C., P.D.F.); Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Programa de Pós-graduação em Farmacologia e Química Medicinal, Rio de Janeiro, Brasil (N.d.M.C., P.D.F., C.A.M.F.); and Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Rio de Janeiro, Brasil (R.H.C.N.F., C.A.M.F.).
Freitas RHCN; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brasil (N.d.M.C., P.D.F.); Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Programa de Pós-graduação em Farmacologia e Química Medicinal, Rio de Janeiro, Brasil (N.d.M.C., P.D.F., C.A.M.F.); and Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Rio de Janeiro, Brasil (R.H.C.N.F., C.A.M.F.).
Fraga CAM; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brasil (N.d.M.C., P.D.F.); Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Programa de Pós-graduação em Farmacologia e Química Medicinal, Rio de Janeiro, Brasil (N.d.M.C., P.D.F., C.A.M.F.); and Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Rio de Janeiro, Brasil (R.H.C.N.F., C.A.M.F.).
Fernandes PD; Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Farmacologia da Dor e da Inflamação, Rio de Janeiro, Brasil (N.d.M.C., P.D.F.); Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Programa de Pós-graduação em Farmacologia e Química Medicinal, Rio de Janeiro, Brasil (N.d.M.C., P.D.F., C.A.M.F.); and Universidade Federal do Rio de Janeiro, Instituto de Ciências Biomédicas, Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Rio de Janeiro, Brasil (R.H.C.N.F., C.A.M.F.) .
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Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2020 Sep; Vol. 374 (3), pp. 420-427. Date of Electronic Publication: 2020 Jun 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Colitis, Ulcerative/*drug therapy
Inflammation/*drug therapy
Animals ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/metabolism ; Colon/drug effects ; Colon/metabolism ; Cytokines/metabolism ; Dextran Sulfate/pharmacology ; Disease Models, Animal ; Female ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Inflammatory Bowel Diseases/chemically induced ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/metabolism ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Mice ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Persistent Viral Presence Determines the Clinical Course of the Disease in COVID-19.
Autorzy :
Chang; College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.
Zhao P; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhang D; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Dong JH; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Xu Z; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Yang G; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Li BY; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Liu HX; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Li BA; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing, China.
Peng XH; Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn.
Wang FS; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.
Xie LX; College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.
Chen Z; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China. Electronic address: .
Dela Cruz CS; Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn.
Sharma L; Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn.
Qin EQ; The Fifth Medical Center, Chinese PLA General Hospital, Beijing, China. Electronic address: .
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Źródło :
The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2020 Sep; Vol. 8 (8), pp. 2585-2591.e1. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*physiopathology
Inflammation/*physiopathology
Pneumonia, Viral/*physiopathology
Adolescent ; Adult ; Aged ; Betacoronavirus ; C-Reactive Protein/immunology ; Child ; Child, Preschool ; Comorbidity ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Female ; Glucocorticoids/therapeutic use ; Humans ; Infant ; Inflammation/epidemiology ; Inflammation/immunology ; Inflammation Mediators/immunology ; Interleukin-6/immunology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Real-Time Polymerase Chain Reaction ; Respiration, Artificial ; Severity of Illness Index ; Young Adult
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans.
Autorzy :
Baggio LL; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada.
Varin EM; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada.
Koehler JA; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada.
Cao X; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada.
Lokhnygina Y; Duke Clinical Research Institute, Duke University, Durham, NC, USA.
Stevens SR; Duke Clinical Research Institute, Duke University, Durham, NC, USA.
Holman RR; Diabetes Trials Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Drucker DJ; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 28; Vol. 11 (1), pp. 3766. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiovascular Diseases/*immunology
Diabetes Mellitus, Type 2/*drug therapy
Dipeptidyl Peptidase 4/*blood
Dipeptidyl-Peptidase IV Inhibitors/*adverse effects
Inflammation/*immunology
Aged ; Animals ; Biomarkers/analysis ; Biomarkers/metabolism ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/immunology ; Diet, Atherogenic/adverse effects ; Diet, High-Fat/adverse effects ; Dipeptidyl Peptidase 4/immunology ; Dipeptidyl Peptidase 4/metabolism ; Dipeptidyl-Peptidase IV Inhibitors/administration & dosage ; Disease Models, Animal ; Female ; Glucagon-Like Peptide-1 Receptor/genetics ; Humans ; Inflammation/blood ; Inflammation/diagnosis ; Inflammation/drug therapy ; Inflammation Mediators/analysis ; Inflammation Mediators/metabolism ; Male ; Metformin/administration & dosage ; Mice ; Mice, Knockout ; Middle Aged ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/blood ; Protein Isoforms/metabolism ; Sitagliptin Phosphate/administration & dosage ; Sitagliptin Phosphate/adverse effects
Czasopismo naukowe
Tytuł :
Inflammation, non-endothelial dependent coronary microvascular function and diastolic function-Are they linked?
Autorzy :
Suhrs HE; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Schroder J; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Bové KB; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Mygind ND; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Frestad D; Department of Cardiology, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Michelsen MM; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Lange T; Department of Public Health, Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark.; Center for Statistical Science, Peking University, Beijing, China.
Gustafsson I; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Kastrup J; Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Prescott E; Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
PloS one [PLoS One] 2020 Jul 16; Vol. 15 (7), pp. e0236035. Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronary Circulation*
Diastole*
Stroke Volume*
Angina Pectoris/*epidemiology
Coronary Vessels/*physiopathology
Inflammation/*physiopathology
Adult ; Aged ; Aged, 80 and over ; Angina Pectoris/etiology ; Angina Pectoris/metabolism ; Angina Pectoris/pathology ; Biomarkers/metabolism ; Case-Control Studies ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; Humans ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Male ; Middle Aged ; Prognosis
Czasopismo naukowe
Tytuł :
A new bisepoxylignan dendranlignan A isolated from Chrysanthemum Flower inhibits the production of inflammatory mediators via the TLR4 pathway in LPS-induced H9c2 cardiomyocytes.
Autorzy :
Zeng M; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Li M; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Chen Y; Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
Zhang J; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Cao Y; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Zhang B; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Feng W; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China.
Zheng X; Henan University of Chinese Medicine, Zhengzhou, 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou, 450046, China. Electronic address: .
Yu Z; Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2020 Sep 15; Vol. 690, pp. 108506. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chrysanthemum/*chemistry
Flowers/*chemistry
Inflammation Mediators/*metabolism
Plant Extracts/*chemistry
Polyynes/*chemistry
Toll-Like Receptor 4/*metabolism
Animals ; Cytokines/chemistry ; Drug Discovery ; Humans ; Inflammation/metabolism ; Lipopolysaccharides/chemistry ; Molecular Docking Simulation ; Molecular Structure ; Myocytes, Cardiac/metabolism ; Polyynes/pharmacology ; Signal Transduction ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Prominent coagulation disorder is closely related to inflammatory response and could be as a prognostic indicator for ICU patients with COVID-19.
Autorzy :
Liu Y; Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, No. 11 Xi-Zhi-Men South Street, Beijing, 100044, China.
Gao W; Emergency Department, Peking University People's Hospital, No. 11 Xi-Zhi-Men South Street, Beijing, 100044, China.
Guo W; Trauma Center, Peking University People's Hospital, Beijing, 100044, China.
Guo Y; Trauma Center, Peking University People's Hospital, Beijing, 100044, China.
Shi M; Emergency Department, Peking University People's Hospital, No. 11 Xi-Zhi-Men South Street, Beijing, 100044, China.
Dong G; Trauma Center, Peking University People's Hospital, Beijing, 100044, China.
Ge Q; Department of Critical Care Unit, Peking University Third Hospital, Beijing, 100191, China.
Zhu J; Emergency Department, Peking University People's Hospital, No. 11 Xi-Zhi-Men South Street, Beijing, 100044, China. .
Lu J; Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, No. 11 Xi-Zhi-Men South Street, Beijing, 100044, China. .
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Źródło :
Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2020 Nov; Vol. 50 (4), pp. 825-832.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Coagulation*
Intensive Care Units*
Betacoronavirus/*pathogenicity
Blood Coagulation Disorders/*virology
Coronavirus Infections/*therapy
Inflammation/*virology
Inflammation Mediators/*blood
Pneumonia, Viral/*therapy
Aged ; Antithrombin III/metabolism ; Biomarkers/blood ; Blood Coagulation Disorders/blood ; Blood Coagulation Disorders/diagnosis ; Blood Coagulation Disorders/mortality ; Coronavirus Infections/diagnosis ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Female ; Fibrin Fibrinogen Degradation Products/metabolism ; Hospital Mortality ; Host-Pathogen Interactions ; Humans ; Inflammation/blood ; Inflammation/diagnosis ; Inflammation/mortality ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Prognosis ; Retrospective Studies ; Risk Factors ; Time Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Colchicine and myocardial infarction: A review.
Autorzy :
Akodad M; Department of Cardiology, Montpellier University Hospital, 34295 Montpellier, France; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295 Montpellier, France. Electronic address: .
Sicard P; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295 Montpellier, France.
Fauconnier J; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295 Montpellier, France.
Roubille F; Department of Cardiology, Montpellier University Hospital, 34295 Montpellier, France; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295 Montpellier, France.
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Źródło :
Archives of cardiovascular diseases [Arch Cardiovasc Dis] 2020 Oct; Vol. 113 (10), pp. 652-659. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Colchicine/*therapeutic use
Inflammation/*drug therapy
Inflammation Mediators/*antagonists & inhibitors
Myocardial Infarction/*drug therapy
Myocarditis/*drug therapy
Animals ; Anti-Inflammatory Agents/adverse effects ; Colchicine/adverse effects ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/physiopathology ; Inflammation Mediators/metabolism ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Myocardial Infarction/physiopathology ; Myocarditis/metabolism ; Myocarditis/pathology ; Myocarditis/physiopathology ; Myocardium/metabolism ; Myocardium/pathology ; Signal Transduction ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Immunity and Stress Responses Are Induced During Ex Situ Heart Perfusion.
Autorzy :
Hatami S; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.; Canadian Transplant Research Program (S. Hatami, X.Q., S. Himmat, J.N., D.H.F.).
White CW; New Brunswick Heart Centre, Saint John, NB, Canada (C.W.W.).
Qi X; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.; Canadian Transplant Research Program (S. Hatami, X.Q., S. Himmat, J.N., D.H.F.).
Buchko M; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.
Ondrus M; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.
Kinnear A; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.
Himmat S; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.; Canadian Transplant Research Program (S. Hatami, X.Q., S. Himmat, J.N., D.H.F.).
Sergi C; Laboratory Medicine and Pathology (C.S.), University of Alberta, Edmonton, Canada.
Nagendran J; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.; Alberta Transplant Institute, Edmonton, Canada (J.N., D.N.F.).; Canadian Transplant Research Program (S. Hatami, X.Q., S. Himmat, J.N., D.H.F.).
Freed DH; Departments of Surgery (S. Hatami, X.Q., M.B., M.O., A.K., S. Himmat, J.N., D.H.F.), University of Alberta, Edmonton, Canada.; Physiology (D.H.F.), University of Alberta, Edmonton, Canada.; Biomedical Engineering (D.H.F.), University of Alberta, Edmonton, Canada.; Alberta Transplant Institute, Edmonton, Canada (J.N., D.N.F.).; Canadian Transplant Research Program (S. Hatami, X.Q., S. Himmat, J.N., D.H.F.).
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Źródło :
Circulation. Heart failure [Circ Heart Fail] 2020 Jun; Vol. 13 (6), pp. e006552. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Oxidative Stress*
Inflammation/*metabolism
Myocardium/*metabolism
Perfusion/*adverse effects
Animals ; Cytokines/metabolism ; Female ; Inflammation/immunology ; Inflammation/pathology ; Inflammation/physiopathology ; Inflammation Mediators/metabolism ; Isolated Heart Preparation ; Lipoproteins, LDL/metabolism ; Malondialdehyde/metabolism ; Myocardium/immunology ; Myocardium/pathology ; Sus scrofa ; Time Factors ; Tissue Survival ; Ventricular Function, Left
Czasopismo naukowe
Tytuł :
Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response.
Autorzy :
Wu R; Laboratory of Chronic Diseases and Environmental Genetics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Zhang H; Laboratory of Chronic Diseases and Environmental Genetics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Zhao M; Department of Plastic and Cosmetic Surgery, The Second Hospital of Dalian Medical University, No. 457 Zhongshan Road, Shahekou District, Dalian 160011, China.
Li J; Laboratory of Chronic Diseases and Environmental Genetics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Hu Y; Experimental Teaching Center, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Fu J; Program of Environmental Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Pi J; Experimental Teaching Center, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China; Program of Environmental Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Wang H; Laboratory of Chronic Diseases and Environmental Genetics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Xu Y; Laboratory of Chronic Diseases and Environmental Genetics, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China; Experimental Teaching Center, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Apr; Vol. 174, pp. 113846. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epidermis/*metabolism
Inflammation Mediators/*metabolism
Keratinocytes/*metabolism
NF-E2-Related Factor 2/*deficiency
Animals ; Cell Line ; Epidermis/pathology ; Fibrosis/metabolism ; Fibrosis/pathology ; Fibrosis/prevention & control ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/prevention & control ; Inflammation Mediators/antagonists & inhibitors ; Keratinocytes/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model.
Autorzy :
Jeon YD; Department of Oriental Medicine Resources, Chonbuk National University, Iksan, Jeollabuk-do, 54596, Republic of Korea.
Lee JH; Department of Immunology and Institute of Medical Sciences, Medical School, Chonbuk National University, Jeonju, Jeonbuk, 54907, Republic of Korea.
Lee YM; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University and Wonkwang-Oriental Medicines Research Institute, Iksan, 54538, South Korea.
Kim DK; Department of Immunology and Institute of Medical Sciences, Medical School, Chonbuk National University, Jeonju, Jeonbuk, 54907, Republic of Korea. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Apr; Vol. 124, pp. 109847. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis, Ulcerative/*drug therapy
Inflammation/*drug therapy
Isoflavones/*pharmacology
Oxidative Stress/*drug effects
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/metabolism ; Colitis, Ulcerative/physiopathology ; Colon/drug effects ; Colon/physiopathology ; Dextran Sulfate ; Disease Models, Animal ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
Effects of Acute Colchicine Administration Prior to Percutaneous Coronary Intervention: COLCHICINE-PCI Randomized Trial.
Autorzy :
Shah B; Section of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S.), VA New York Harbor Health Care System.; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Pillinger M; Section of Rheumatology, Department of Medicine (M.P.), VA New York Harbor Health Care System.; Division of Rheumatology, Department of Medicine (M.P., B.C.), New York University School of Medicine.
Zhong H; Division of Biostatistics, Department of Population Health (H.Z., Y.X.), New York University School of Medicine.
Cronstein B; Division of Rheumatology, Department of Medicine (M.P., B.C.), New York University School of Medicine.
Xia Y; Division of Biostatistics, Department of Population Health (H.Z., Y.X.), New York University School of Medicine.
Lorin JD; Section of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S.), VA New York Harbor Health Care System.; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Smilowitz NR; Section of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S.), VA New York Harbor Health Care System.; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Feit F; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Ratnapala N; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Keller NM; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
Katz SD; Division of Cardiology, Department of Medicine (B.S., J.D.L., N.R.S., F.F., N.R., N.M.K., S.D.K.), New York University School of Medicine.
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Źródło :
Circulation. Cardiovascular interventions [Circ Cardiovasc Interv] 2020 Apr; Vol. 13 (4), pp. e008717. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Acute Coronary Syndrome/*therapy
Anti-Inflammatory Agents/*administration & dosage
Colchicine/*administration & dosage
Coronary Artery Disease/*therapy
Inflammation/*prevention & control
Percutaneous Coronary Intervention/*adverse effects
Acute Coronary Syndrome/diagnostic imaging ; Acute Coronary Syndrome/mortality ; Administration, Oral ; Aged ; Anti-Inflammatory Agents/adverse effects ; Biomarkers/blood ; C-Reactive Protein/metabolism ; Colchicine/adverse effects ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/mortality ; Double-Blind Method ; Drug Administration Schedule ; Female ; Humans ; Inflammation/blood ; Inflammation/etiology ; Inflammation/mortality ; Inflammation Mediators/blood ; Interleukin-6/blood ; Male ; Middle Aged ; New York City ; Percutaneous Coronary Intervention/instrumentation ; Percutaneous Coronary Intervention/mortality ; Prospective Studies ; Risk Factors ; Stents ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Accumulation of Pericardial Fat Is Associated With Alterations in Heart Rate Variability Patterns in Hypercholesterolemic Pigs.
Autorzy :
Uceda DE; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.
Zhu XY; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.
Woollard JR; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.
Ferguson CM; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.
Patras I; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.
Carlson DF; Recombinetics, Inc, St. Paul, MN (D.F.C.).
Asirvatham SJ; Department of Cardiovascular Diseases (S.J.A., A.L., L.O.L.), Mayo Clinic, Rochester, MN.
Lerman A; Department of Cardiovascular Diseases (S.J.A., A.L., L.O.L.), Mayo Clinic, Rochester, MN.
Lerman LO; Division of Nephrology and Hypertension (D.E.U., X.-Y.Z., J.R.W., C.M.F., I.P., L.O.L.), Mayo Clinic, Rochester, MN.; Department of Cardiovascular Diseases (S.J.A., A.L., L.O.L.), Mayo Clinic, Rochester, MN.
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Źródło :
Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2020 Apr; Vol. 13 (4), pp. e007614. Date of Electronic Publication: 2020 Mar 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adiposity*
Heart Rate*
Adipose Tissue/*physiopathology
Arrhythmias, Cardiac/*etiology
Autonomic Nervous System/*physiopathology
Hypercholesterolemia/*complications
Inflammation/*etiology
Pericardium/*physiopathology
Adipose Tissue/metabolism ; Animals ; Animals, Genetically Modified ; Arrhythmias, Cardiac/metabolism ; Arrhythmias, Cardiac/physiopathology ; Autonomic Nervous System/metabolism ; Cholesterol/blood ; Disease Models, Animal ; Hypercholesterolemia/metabolism ; Hypercholesterolemia/physiopathology ; Inflammation/metabolism ; Inflammation/physiopathology ; Inflammation Mediators/metabolism ; Male ; Norepinephrine/blood ; Pericardium/metabolism ; Swine ; Swine, Miniature/genetics ; Time Factors ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Extracellular vesicles: new players in regulating vascular barrier function.
Autorzy :
Chatterjee V; Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida.
Yang X; Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida.
Ma Y; Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida.
Wu MH; Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida.
Yuan SY; Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida.; Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2020 Dec 01; Vol. 319 (6), pp. H1181-H1196. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Capillary Permeability*
Endothelium, Vascular/*metabolism
Extracellular Vesicles/*metabolism
Inflammation/*metabolism
Inflammation Mediators/*metabolism
Animals ; Betacoronavirus/pathogenicity ; Coronavirus Infections/metabolism ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Endothelium, Vascular/pathology ; Endothelium, Vascular/virology ; Extracellular Vesicles/pathology ; Extracellular Vesicles/virology ; Host-Pathogen Interactions ; Humans ; Inflammation/pathology ; Pandemics ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; Signal Transduction
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Cordycepin protects against acute pancreatitis by modulating NF-κB and NLRP3 inflammasome activation via AMPK.
Autorzy :
Yang J; School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu, China. Electronic address: .
Zhou Y; School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu, China.
Shi J; School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Jun 15; Vol. 251, pp. 117645. Date of Electronic Publication: 2020 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Deoxyadenosines/*pharmacology
Inflammasomes/*metabolism
Inflammation/*prevention & control
Pancreatitis/*prevention & control
Acute Disease ; Animals ; Biomarkers/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred ICR ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Protective Agents/pharmacology
Czasopismo naukowe
Tytuł :
TRIM32 promotes inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes.
Autorzy :
Liang T; Department of Orthopedics, Gansu Traditional Chinese Medicine University, Lanzhou, China.
Song M; Department of Orthopedics, Gansu Traditional Chinese Medicine University, Lanzhou, China.
Xu K; Department of Orthopedics, Affiliated Hospital of Gansu Traditional Chinese Medicine University, Lanzhou, China.
Guo C; Department of Orthopedics, Affiliated Hospital of Gansu Traditional Chinese Medicine University, Lanzhou, China.
Xu H; Department of Orthopedics, Affiliated Hospital of Gansu Traditional Chinese Medicine University, Lanzhou, China.
Zhang H; Department of Orthopedics, Affiliated Hospital of Gansu Traditional Chinese Medicine University, Lanzhou, China.
Xu L; Department of Dermatology, Affiliated Hospital of Gansu Traditional Chinese Medicine University, Lanzhou, China.
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Źródło :
Scandinavian journal of immunology [Scand J Immunol] 2020 Jun; Vol. 91 (6), pp. e12876. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Arthritis, Rheumatoid/*metabolism
Fibroblasts/*immunology
Inflammation/*metabolism
Synoviocytes/*immunology
Transcription Factors/*metabolism
Tripartite Motif Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Arthritis, Rheumatoid/immunology ; Cell Proliferation ; Cells, Cultured ; Cytokines/metabolism ; Humans ; Inflammation/immunology ; Inflammation Mediators/metabolism ; NF-kappa B/metabolism ; Signal Transduction ; TNF Receptor-Associated Factor 2/metabolism ; Transcription Factors/genetics ; Tripartite Motif Proteins/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination ; Up-Regulation
Czasopismo naukowe
Tytuł :
[Fasting reduces inflammation associated with chronic inflammatory diseases without affecting the immune response to acute infections].
Autorzy :
Adda L; Master 2 Immunologie Translationnelle et Biothérapies, Mention BMC, Sorbonne Université, Paris, France.
Melhem SA; Master 2 Immunologie Translationnelle et Biothérapies, Mention BMC, Sorbonne Université, Paris, France.
Pol J; Équipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Inserm U1138, Université de Paris, Sorbonne Université, Paris, France. - Gustave Roussy Cancer Campus, Villejuif, France. - Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France.
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Transliterated Title :
Le jeûne réduit l’inflammation associée aux maladies inflammatoires chroniques sans altérer la réponse immunitaire aux infections aiguës.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2020 Jun-Jul; Vol. 36 (6-7), pp. 665-668. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Wiadomości
MeSH Terms :
Fasting/*physiology
Infections/*immunology
Inflammation/*prevention & control
Acute Disease ; Animals ; Chronic Disease ; Down-Regulation ; Humans ; Immune System Phenomena/physiology ; Infections/pathology ; Inflammation/immunology ; Inflammation/pathology ; Inflammation Mediators/metabolism
Periodyk
Tytuł :
Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis.
Autorzy :
Roquilly A; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France. .; Université de Nantes, CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie Réanimation Chirurgicale, Hôtel Dieu, Nantes, France. .; Department of Microbiology and Immunology, Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Parkville, Victoria, Australia. .
Jacqueline C; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.
Davieau M; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.
Mollé A; Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR1064, ITUN, Nantes, France.
Sadek A; Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR1064, ITUN, Nantes, France.; Department of Biology, Faculty of Science, Moulay Ismail University, Zitoune, Meknes, Morocco.
Fourgeux C; Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR1064, ITUN, Nantes, France.
Rooze P; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.; Université de Nantes, CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie Réanimation Chirurgicale, Hôtel Dieu, Nantes, France.
Broquet A; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.
Misme-Aucouturier B; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.
Chaumette T; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.
Vourc'h M; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France.; Université de Nantes, CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie Réanimation Chirurgicale, Hôtel Dieu, Nantes, France.
Cinotti R; Université de Nantes, CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie Réanimation Chirurgicale, Hôtel Dieu, Nantes, France.
Marec N; Plateforme Cytocell, SFR François Bonamy, Nantes, France.
Gauttier V; Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR1064, ITUN, Nantes, France.
McWilliam HEG; Department of Microbiology and Immunology, Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Parkville, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Altare F; CRCINA, INSERM, Université de Nantes, CHU de Nantes, Nantes, France.
Poschmann J; Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR1064, ITUN, Nantes, France. .
Villadangos JA; Department of Microbiology and Immunology, Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Parkville, Victoria, Australia. .; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia. .
Asehnoune K; Université de Nantes, EA3826 Thérapeutiques Anti-Infectieuses, Institut de Recherche en Santé 2 Nantes Biotech, Nantes, France. .; Université de Nantes, CHU Nantes, Pôle Anesthésie-Réanimation, Service d'Anesthésie Réanimation Chirurgicale, Hôtel Dieu, Nantes, France. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Jun; Vol. 21 (6), pp. 636-648. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epigenesis, Genetic*
Inflammation/*etiology
Lung/*immunology
Lung/*metabolism
Macrophages, Alveolar/*metabolism
Animals ; Biomarkers ; Cellular Reprogramming ; Cytokines/metabolism ; Humans ; Immune Tolerance ; Immunophenotyping ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Lung/pathology ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages, Alveolar/immunology ; Mice ; Monocytes/immunology ; Monocytes/metabolism ; Phagocytosis/immunology ; Pneumonia/etiology ; Pneumonia/metabolism ; Pneumonia/pathology ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Tytuł :
Cellular Contributors to Hypothalamic Inflammation in Obesity.
Autorzy :
Lee CH; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Suk K; Department of Pharmacology, School of Medicine, Kyungpook National University College of Medicine, Daegu 41944, Korea.
Yu R; Department of Food Science and Nutrition, University of Ulsan, Ulsan 44610, Korea.
Kim MS; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.; Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
Molecules and cells [Mol Cells] 2020 May 31; Vol. 43 (5), pp. 431-437.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adipose Tissue/*immunology
Hypothalamus/*immunology
Inflammation/*metabolism
Macrophages/*immunology
Microglia/*immunology
Neurons/*immunology
Obesity/*immunology
Animals ; Cytokines/metabolism ; Diet, High-Fat ; Energy Metabolism ; Humans ; Immunity, Cellular ; Neurogenic Inflammation
Czasopismo naukowe
Tytuł :
Association between inflammation and skeletal muscle proteolysis, skeletal mass and strength in elderly heart failure patients and their prognostic implications.
Autorzy :
Koshikawa M; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Harada M; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Noyama S; Division of Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Japan.
Kiyono K; Division of Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Japan.
Motoike Y; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Nomura Y; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Nishimura A; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Izawa H; Department of Cardiology, Fujita Health University School of Medicine, Bantane Hospital, Nagoya, Japan.
Watanabe E; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. .
Ozaki Y; Department of Cardiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
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Źródło :
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2020 May 15; Vol. 20 (1), pp. 228. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Frail Elderly*
Muscle Strength*
Frailty/*diagnosis
Heart Failure/*diagnosis
Inflammation/*diagnosis
Muscle, Skeletal/*physiopathology
Sarcopenia/*diagnosis
Age Factors ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Case-Control Studies ; Exercise Tolerance ; Female ; Frailty/blood ; Frailty/physiopathology ; Heart Failure/mortality ; Heart Failure/physiopathology ; Heart Failure/therapy ; Hospitalization ; Humans ; Inflammation/blood ; Inflammation/mortality ; Inflammation/therapy ; Inflammation Mediators/blood ; Male ; Prognosis ; Prospective Studies ; Proteolysis ; Risk Assessment ; Risk Factors ; Sarcopenia/mortality ; Sarcopenia/physiopathology ; Sarcopenia/therapy
Czasopismo naukowe
Tytuł :
Atherosclerotic Coronary Plaque Is Associated With Adventitial Vasa Vasorum and Local Inflammation in Adjacent Epicardial Adipose Tissue in Fresh Cadavers.
Autorzy :
Ito H; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Wakatsuki T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Yamaguchi K; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Fukuda D; Department of Cardio-Diabetes Medicine, Tokushima University Graduate School of Biomedical Sciences.
Kawabata Y; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Matsuura T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Kusunose K; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Ise T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Tobiume T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Yagi S; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Yamada H; Department of Community Medicine for Cardiology, Tokushima University Graduate School of Biomedical Sciences.
Soeki T; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
Tsuruo Y; Department of Anatomy and Cell Biology, Tokushima University Graduate School of Biomedical Sciences.
Sata M; Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.
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Źródło :
Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2020 Apr 24; Vol. 84 (5), pp. 769-775. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Plaque, Atherosclerotic*
Ultrasonography, Interventional*
Adipose Tissue/*diagnostic imaging
Adventitia/*diagnostic imaging
Coronary Artery Disease/*diagnostic imaging
Coronary Vessels/*diagnostic imaging
Inflammation/*diagnostic imaging
Vasa Vasorum/*diagnostic imaging
Adipose Tissue/chemistry ; Adipose Tissue/pathology ; Adventitia/chemistry ; Adventitia/pathology ; Aged ; Aged, 80 and over ; Cadaver ; Coronary Artery Disease/metabolism ; Coronary Artery Disease/pathology ; Coronary Vessels/chemistry ; Coronary Vessels/pathology ; Female ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/analysis ; Male ; Predictive Value of Tests ; Vasa Vasorum/chemistry ; Vasa Vasorum/pathology
Czasopismo naukowe
Tytuł :
TAK1 signaling activity links the mast cell cytokine response and degranulation in allergic inflammation.
Autorzy :
Watson CJF; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
Maguire ARR; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
Rouillard MM; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
Crozier RWE; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
Yousef M; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
Bruton KM; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Fajardo VA; Department of Kinesiology, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
MacNeil AJ; Department of Health Sciences, Faculty of Applied Health Sciences, Cairns Family Health and Bioscience Research Complex, Brock University, Niagara Region, Ontario, Canada.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Apr; Vol. 107 (4), pp. 649-661. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Degranulation*/drug effects
Signal Transduction*
Cytokines/*metabolism
Hypersensitivity/*enzymology
Inflammation/*pathology
MAP Kinase Kinase Kinases/*metabolism
Mast Cells/*physiology
Animals ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Calcium/metabolism ; Female ; Gene Expression Regulation/drug effects ; Hypersensitivity/genetics ; Immunoglobulin E/metabolism ; Inflammation/genetics ; Inflammation Mediators/metabolism ; MAP Kinase Kinase Kinases/antagonists & inhibitors ; Mast Cells/drug effects ; Mice, Inbred C57BL ; Models, Biological ; NF-KappaB Inhibitor alpha/genetics ; NF-KappaB Inhibitor alpha/metabolism ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Phosphoserine/metabolism ; Proto-Oncogene Proteins c-kit/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, IgE/metabolism ; Zearalenone/analogs & derivatives ; Zearalenone/pharmacology
Czasopismo naukowe
Tytuł :
Ketamine inhibits LPS-mediated BV2 microglial inflammation via NMDA receptor blockage.
Autorzy :
Lu Y; Department of Anaesthesiology, The Obstetrics and Gynecology Hospital of Fudan University, No. 128 Shenyang road, Shanghai, 200090, China.
Ding X; Department of Anaesthesiology, Huashan Hospital, Fudan University, No.12 Middle Wulumuqi road, Shanghai, 200040, China.
Wu X; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Fudan University, No. 270 Dongan road, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, No. 270 Dongan road, Shanghai, China.
Huang S; Department of Anaesthesiology, The Obstetrics and Gynecology Hospital of Fudan University, No. 128 Shenyang road, Shanghai, 200090, China.
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Źródło :
Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2020 Apr; Vol. 34 (2), pp. 229-237. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation/*drug therapy
Ketamine/*pharmacology
Microglia/*drug effects
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Anesthetics, Dissociative/pharmacology ; Animals ; Calcium/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cell Line ; Cytokines/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Lipopolysaccharides ; Mice ; Microglia/pathology ; NF-kappa B/metabolism ; Phosphorylation/drug effects
Czasopismo naukowe
Tytuł :
Overexpression of GILZ in macrophages limits systemic inflammation while increasing bacterial clearance in sepsis in mice.
Autorzy :
Ellouze M; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
Vigouroux L; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
Tcherakian C; Service de Pneumologie, Hôpital Foch, Suresnes, France.
Woerther PL; Department of Microbiology and Infection Control, Henri-Mondor Hospital, APHP, Créteil, France.; EA 7380 Dynamyc, EnvA, UPEC, Paris-Est University, Créteil, France.
Guguin A; IMRB, Créteil, France.
Robert O; Faculty of Medicine, Univ. Paris-Sud, France.; INSERM U996, Clamart, France.
Surenaud M; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
Tran T; Faculty of Medicine, Univ. Paris-Sud, France.; INSERM U996, Clamart, France.
Calmette J; Faculty of Medicine, Univ. Paris-Sud, France.; INSERM U996, Clamart, France.
Barbin T; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
Perlemuter G; Faculty of Medicine, Univ. Paris-Sud, Le Kremlin Bicêtre, France.; INSERM U996, Clamart, France.; Service de Gastro-Entérologie, AP-HP, Clamart, France.
Cassard AM; Faculty of Medicine, Univ. Paris-Sud, France.; INSERM U996, Clamart, France.
Launay P; Univ. Paris Diderot, Sorbonne Paris Cité, Paris, France.; Laboratoire d'Excellence INFLAMEX, INSERM U1149, Paris, France.
Maxime V; Hôpital Raymond-Poincaré (AP-HP), INSERM U1173, Univ. Versailles SQY, Garches, France.
Annane D; Hôpital Raymond-Poincaré (AP-HP), INSERM U1173, Univ. Versailles SQY, Garches, France.
Levy Y; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
Godot V; Faculty of Medicine, Univ. Paris Est Créteil, Créteil, France.; Vaccine Research Institute-VRI, Créteil, France.; INSERM U955-Team 16, Créteil, France.
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Źródło :
European journal of immunology [Eur J Immunol] 2020 Apr; Vol. 50 (4), pp. 589-602. Date of Electronic Publication: 2020 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*metabolism
Macrophages/*immunology
Monocytes/*immunology
Sepsis/*metabolism
Transcription Factors/*metabolism
Animals ; Anti-Inflammatory Agents/metabolism ; Bacterial Load ; Cells, Cultured ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression Regulation ; Glucocorticoids/metabolism ; Humans ; Immunity, Innate ; Immunomodulation ; Inflammation Mediators/metabolism ; Mice ; Mice, Transgenic ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Serum uric acid may modulate the inflammatory response after primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction.
Autorzy :
Mandurino-Mirizzi A; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.; University of Pavia.
Demarchi A; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.; University of Pavia.
Ruffinazzi M; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.; University of Pavia.
Cornara S; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.; University of Pavia.
Somaschini A; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.; University of Pavia.
Crimi G; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.
Ferlini M; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.
Camporotondo R; Coronary care unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Gnecchi M; University of Pavia.; Coronary care unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Ferrario M; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.
Oltrona Visconti L; Division of Cardiology, Fondazione IRCCS Policlinico San Matteo.
De Ferrari GM; University of Pavia.; Coronary care unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
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Źródło :
Journal of cardiovascular medicine (Hagerstown, Md.) [J Cardiovasc Med (Hagerstown)] 2020 Apr; Vol. 21 (4), pp. 337-339.
Typ publikacji :
Letter
MeSH Terms :
Inflammation/*etiology
Percutaneous Coronary Intervention/*adverse effects
ST Elevation Myocardial Infarction/*therapy
Uric Acid/*blood
Aged ; Biomarkers/blood ; C-Reactive Protein/metabolism ; Female ; Humans ; Inflammation/blood ; Inflammation Mediators/blood ; Interleukin-6/blood ; Male ; Middle Aged ; ST Elevation Myocardial Infarction/blood ; ST Elevation Myocardial Infarction/diagnostic imaging ; Treatment Outcome
Opinia redakcyjna
Tytuł :
Critical Role of p38 in Spinal Cord Injury by Regulating Inflammation and Apoptosis in a Rat Model.
Autorzy :
Zhang HW; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
Ding JD; Department of Orthopedics, No. 904 Hospital of the Joint Logistics Support Force of PLA, Changzhou, China.
Zhang ZS; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
Zhao SS; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
Duan KY; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
Zhu BQ; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
Zhao WF; Central Health Center of Linghe Town, Anqiu, Shandong, China.
Chai ZT; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Liu XW; Department of Spinal Surgery, Affiliated Hospital of Weifang Medical University, Weifang Medical University, Weifang, Shandong, China.
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Źródło :
Spine [Spine (Phila Pa 1976)] 2020 Apr 01; Vol. 45 (7), pp. E355-E363.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Apoptosis/*physiology
Inflammation Mediators/*metabolism
Spinal Cord Injuries/*metabolism
p38 Mitogen-Activated Protein Kinases/*biosynthesis
Animals ; Apoptosis/drug effects ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Imidazoles/pharmacology ; Imidazoles/therapeutic use ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/antagonists & inhibitors ; Locomotion/drug effects ; Locomotion/physiology ; Male ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Recovery of Function/drug effects ; Recovery of Function/physiology ; Spinal Cord Injuries/drug therapy ; Spinal Cord Injuries/pathology ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Anti-inflammatory diet: Necessity of scientific spotlight and challenges.
Autorzy :
Watanabe K; Yokohama University of Pharmacy, 601 Matono-cho, Totsuka-ku, Yokohama 245-0066, Japan. Electronic address: .
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Źródło :
Complementary therapies in medicine [Complement Ther Med] 2020 May; Vol. 50, pp. 102281. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji :
Editorial; Introductory Journal Article
MeSH Terms :
Aging/*metabolism
Diet/*methods
Inflammation/*diet therapy
Antioxidants/metabolism ; Fish Oils/administration & dosage ; Fish Oils/pharmacology ; Humans ; Inflammation Mediators/metabolism ; Phytotherapy/methods
Czasopismo naukowe
Tytuł :
Tumour dormancy in inflammatory microenvironment: A promising therapeutic strategy for cancer-related bone metastasis.
Autorzy :
Hu W; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Zhang L; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Dong Y; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Tian Z; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Chen Y; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .; Department of Orthopedics, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .
Dong S; Department of Biomedical Materials Science, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .; Department of Orthopedics, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .; State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (24), pp. 5149-5169. Date of Electronic Publication: 2020 Jun 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Bone Neoplasms/*metabolism
Breast Neoplasms/*metabolism
Inflammation/*metabolism
Prostatic Neoplasms/*metabolism
Bone Neoplasms/genetics ; Bone Neoplasms/pathology ; Bone Neoplasms/secondary ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Male ; Neoplasm Metastasis ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Prostatic Neoplasms/pathology ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
IL-27 along with IL-28B ameliorates the pulmonary redox impairment, inflammation and immunosuppression in benzo(a)pyrene induced lung cancer bearing mice.
Autorzy :
Majumder D; Immunology & Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar 799022, India. Electronic address: .
Debnath R; Immunology & Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar 799022, India. Electronic address: .
Maiti D; Immunology & Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar 799022, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118384. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Immunosuppression*
Oxidative Stress*
Benzo(a)pyrene/*toxicity
Cytokines/*metabolism
Inflammation/*prevention & control
Interleukin-27/*metabolism
Lung Neoplasms/*prevention & control
Animals ; Cytokines/genetics ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-27/genetics ; Lung Neoplasms/chemically induced ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Mice ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
The Collision of Meta-Inflammation and SARS-CoV-2 Pandemic Infection.
Autorzy :
Huizinga GP; Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, Michigan.
Singer BH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Michigan Center for Integrative Research in Critical Care, University of Michigan Medical School, Ann Arbor, Michigan.
Singer K; Department of Pediatrics and Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan.
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Źródło :
Endocrinology [Endocrinology] 2020 Nov 01; Vol. 161 (11).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Inflammation/*immunology
Obesity/*immunology
Pneumonia, Viral/*immunology
Betacoronavirus/physiology ; Body Weight/immunology ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate/immunology ; Inflammation/metabolism ; Inflammation/virology ; Obesity/metabolism ; Obesity/virology ; Pandemics ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?
Autorzy :
Luscombe VB; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Lucy D; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.; Department of Chemistry and University of Oxford, Oxford, United Kingdom.
Bataille CJR; Department of Chemistry and University of Oxford, Oxford, United Kingdom.
Russell AJ; Department of Chemistry and University of Oxford, Oxford, United Kingdom.; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Nov; Vol. 39 (11), pp. 1926-1937. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Fatty Acids/*genetics
Inflammation/*genetics
Receptors, G-Protein-Coupled/*genetics
Fatty Acids/metabolism ; Gastrointestinal Tract/metabolism ; Gastrointestinal Tract/pathology ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Ligands ; Macrophages/metabolism ; Phagocytosis/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Nobiletin ameliorates high-fat diet-induced vascular and renal changes by reducing inflammation with modulating AdipoR1 and TGF-β1 expression in rats.
Autorzy :
Bunbupha S; Faculty of Medicine, Mahasarakham University, Maha Sarakham 44000, Thailand. Electronic address: .
Apaijit K; Faculty of Medicine, Mahasarakham University, Maha Sarakham 44000, Thailand.
Maneesai P; Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Cardiovascular Research Group, Khon Kaen University, Khon Kaen 40002, Thailand.
Prasarttong P; Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Cardiovascular Research Group, Khon Kaen University, Khon Kaen 40002, Thailand.
Pakdeechote P; Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand; Cardiovascular Research Group, Khon Kaen University, Khon Kaen 40002, Thailand.
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118398. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat/*adverse effects
Flavones/*pharmacology
Inflammation/*prevention & control
Kidney Diseases/*drug therapy
Receptors, Adiponectin/*metabolism
Transforming Growth Factor beta1/*metabolism
Vascular Diseases/*drug therapy
Animals ; Antioxidants/pharmacology ; Gene Expression Regulation ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Kidney Diseases/etiology ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Male ; Rats ; Rats, Sprague-Dawley ; Receptors, Adiponectin/genetics ; Transforming Growth Factor beta1/genetics ; Vascular Diseases/etiology ; Vascular Diseases/metabolism ; Vascular Diseases/pathology
Czasopismo naukowe
Tytuł :
Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice.
Autorzy :
Liong S; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia; .
Oseghale O; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
To EE; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Brassington K; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Erlich JR; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Luong R; Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Liong F; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Brooks R; Clinical and Health Sciences, University of South Australia, Adelaide, SA 5001, Australia.
Martin C; Discipline of Histopathology, School of Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 2, Ireland.; Sir Patrick Dun's Laboratory, Central Pathology Laboratory, St James's Hospital, Dublin 8, Ireland.; Emer Casey Research Laboratory, Molecular Pathology Laboratory, The Coombe Women and Infants University Hospital, Dublin 8, Ireland.; Irish Cervical Screening Research Consortium (CERVIVA), Trinity College Dublin, Dublin 2, Ireland.
O'Toole S; Discipline of Histopathology, School of Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 2, Ireland.; Sir Patrick Dun's Laboratory, Central Pathology Laboratory, St James's Hospital, Dublin 8, Ireland.; Emer Casey Research Laboratory, Molecular Pathology Laboratory, The Coombe Women and Infants University Hospital, Dublin 8, Ireland.; Irish Cervical Screening Research Consortium (CERVIVA), Trinity College Dublin, Dublin 2, Ireland.
Vinh A; Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Melbourne Campus, Bundoora, VIC 3086, Australia.
O'Neill LAJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Bozinovski S; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Vlahos R; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
Papagianis PC; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia.
O'Leary JJ; Discipline of Histopathology, School of Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 2, Ireland.; Sir Patrick Dun's Laboratory, Central Pathology Laboratory, St James's Hospital, Dublin 8, Ireland.; Emer Casey Research Laboratory, Molecular Pathology Laboratory, The Coombe Women and Infants University Hospital, Dublin 8, Ireland.; Irish Cervical Screening Research Consortium (CERVIVA), Trinity College Dublin, Dublin 2, Ireland.
Brooks DA; Clinical and Health Sciences, University of South Australia, Adelaide, SA 5001, Australia.; Discipline of Histopathology, School of Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin 2, Ireland.
Selemidis S; School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, VIC 3083, Australia; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 06; Vol. 117 (40), pp. 24964-24973. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity/*genetics
Immunity, Innate/*genetics
Inflammation/*genetics
Influenza A virus/*genetics
Animals ; Blood Vessels/metabolism ; Blood Vessels/pathology ; Female ; Fetus/immunology ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Inflammation/virology ; Influenza A virus/pathogenicity ; Influenza, Human/genetics ; Influenza, Human/immunology ; Influenza, Human/virology ; Membrane Glycoproteins/genetics ; Mice ; Monocytes/metabolism ; Monocytes/pathology ; Placenta/blood supply ; Placenta/immunology ; Placenta/virology ; Pregnancy ; T-Lymphocytes/immunology ; T-Lymphocytes/virology ; Toll-Like Receptor 7/genetics ; Toll-Like Receptor 9/genetics
Czasopismo naukowe
Tytuł :
Glucosamine and O-GlcNAcylation: a novel immunometabolic therapeutic target for OA and chronic, low-grade systemic inflammation?
Autorzy :
Herrero-Beaumont G; Rheumatology, Fundacion Jimenez Diaz, Madrid, Spain .; Joint and Bone Research Unit, Rheumatology Department, IIS-Fundacion Jimenez Diaz, Madrid, Spain.
Largo R; Joint and Bone Research Unit, Rheumatology Department, IIS-Fundacion Jimenez Diaz, Madrid, Spain.
Pokaż więcej
Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2020 Oct; Vol. 79 (10), pp. 1261-1263. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation*/complications
Inflammation*/immunology
Inflammation*/metabolism
Osteoarthritis*/complications
Osteoarthritis*/immunology
Osteoarthritis*/metabolism
Glucosamine/*pharmacology
Acetylation ; Animals ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/immunology ; Cardiovascular Diseases/metabolism ; Humans
Raport

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