Temat: "Inflammation Mediators" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: Immune-mediated inflammation across disease boundaries: breaking down research silos.
Autorzy :: Buckley CD; The Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Chernajovsky L; The Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK.
Chernajovsky Y; The Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK. .; Queen Mary University of London, London, UK. .
Modis LK; Immunology Research, GSK, Stevenage, UK.
O'Neill LA; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Brown D; British Society for Immunology, London, UK.
Connor R; Juvenile Diabetes Research Foundation, London, UK.
Coutts D; Multiple Sclerosis Society, London, UK.
Waterman EA; Versus Arthritis, Chesterfield, UK.
Tak PP; The Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK.; University of Cambridge, Cambridge, UK.; Candel Therapeutics, Needham, Massachusetts, USA.; Multimorbidity Steering Group, Strategic Priorities Fund, Swindon, UK.; Pokaż więcej
Źródło :: Nature immunology [Nat Immunol] 2021 Nov; Vol. 22 (11), pp. 1344-1348.
Typ publikacji :: Journal Article
MeSH Terms :: Allergy and Immunology*
Biomedical Research*
Immune System/*immunology
Inflammation/*immunology
Inflammation Mediators/*immunology
Animals ; Anti-Inflammatory Agents/therapeutic use ; Diffusion of Innovation ; Drug Discovery ; Humans ; Immune System/drug effects ; Immune System/metabolism ; Immune System/pathology ; Immunotherapy ; Inflammation/diagnosis ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation Mediators/antagonists & inhibitors ; Inflammation Mediators/metabolism ; Molecular Targeted Therapy ; Signal Transduction
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: The anti-cancer potential of 2,4,6 tris-methyphenylamino1,3,5-triazine compound against mammary glands cancer: Via down-regulating the hormonal, inflammatory mediators, and oxidative stress.
Autorzy :: Mehmood Y; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan.
Anwar F; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan. Electronic address: .
Saleem U; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Hira S; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan. Electronic address: .
Ahmad B; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan. Electronic address: .
Bashir M; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan.
Imtiaz MT; Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan.
Najm S; Faculty of Pharmacy, Lahore College of Pharmaceutical Sciences, Lahore 55150, Pakistan.
Ismail T; COMSAT University, Department of Pharmacy, Abbottabad, Pakistan. Electronic address: .; Pokaż więcej
Źródło :: Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 119994. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :: Journal Article
MeSH Terms :: Antineoplastic Agents/*pharmacology
Breast Neoplasms/*metabolism
Estrogens/*metabolism
Inflammation Mediators/*antagonists & inhibitors
Progesterone/*metabolism
Triazines/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Down-Regulation ; Female ; Humans ; Inflammation Mediators/metabolism ; MCF-7 Cells ; Oxidative Stress/drug effects ; Oxidoreductases/metabolism ; Progesterone/antagonists & inhibitors ; Rats ; Tamoxifen/pharmacology ; Triazines/chemistry
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: HDAC3 inhibitor suppresses endothelial-to-mesenchymal transition via modulating inflammatory response in atherosclerosis.
Autorzy :: Chen L; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Shang C; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang B; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wang G; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jin Z; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yao F; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yue Z; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Bai L; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Wang R; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Zhao S; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Liu E; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Wang W; Department of Medical Laboratory Animal Science, Xi'an Jiaotong University Health Science Center, Xi'an, China; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China. Electronic address: .; Pokaż więcej
Źródło :: Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114716. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Atherosclerosis/*metabolism
Endothelium/*metabolism
Epithelial-Mesenchymal Transition/*physiology
Histone Deacetylase Inhibitors/*pharmacology
Histone Deacetylases/*metabolism
Inflammation Mediators/*metabolism
Acrylamides/pharmacology ; Acrylamides/therapeutic use ; Animals ; Atherosclerosis/drug therapy ; Endothelium/drug effects ; Epithelial-Mesenchymal Transition/drug effects ; Histone Deacetylase Inhibitors/therapeutic use ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Inflammation Mediators/antagonists & inhibitors ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phenylenediamines/pharmacology ; Phenylenediamines/therapeutic use ; THP-1 Cells
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives.
Autorzy :: Wedn AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
El-Bassossy HM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Eid AH; Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar; Biomedical and Pharmaceutical Research Unit, QU Health, Qatar University, Doha, Qatar.
El-Mas MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmacology and Toxicology, Faculty of Medicine, Kuwait University, Kuwait. Electronic address: .; Pokaż więcej
Źródło :: Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114703. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :: Inflammation Mediators/*antagonists & inhibitors
Neuroimmunomodulation/*physiology
Nicotinic Agonists/*metabolism
Pre-Eclampsia/*metabolism
Receptors, Nicotinic/*metabolism
Animals ; Cholinesterases/metabolism ; Female ; Humans ; Inflammation Mediators/metabolism ; Neuroimmunomodulation/drug effects ; Nicotinic Agonists/pharmacology ; Nicotinic Agonists/therapeutic use ; Pre-Eclampsia/drug therapy ; Pregnancy
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Artemisia anomala Herba Alleviates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice and the Production of Pro-Inflammatory Mediators in Tumor Necrosis Factor Alpha-/Interferon Gamma-Induced HaCaT Cells.
Autorzy :: Yang JH; Korean Medicine (KM) Application Center, Korea Institute of Oriental Medicine, 70 Cheomdan-ro, Dong-gu, Daegu 41062, Korea.
Kim KY; Korean Medicine (KM) Application Center, Korea Institute of Oriental Medicine, 70 Cheomdan-ro, Dong-gu, Daegu 41062, Korea.
Kim YW; School of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Park KI; Department of Veterinary Physiology, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2021 Sep 06; Vol. 26 (17). Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :: Journal Article
MeSH Terms :: Anti-Inflammatory Agents/*chemistry
Artemisia/*chemistry
Dermatitis, Atopic/*metabolism
Dinitrochlorobenzene/*chemistry
Inflammation Mediators/*chemistry
Plant Extracts/*chemistry
Animals ; Anti-Inflammatory Agents/pharmacology ; Chemokines/metabolism ; Cytokines/metabolism ; Dinitrochlorobenzene/metabolism ; Disease Models, Animal ; HaCaT Cells ; Humans ; Inflammation Mediators/pharmacology ; Interferon-gamma/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Plant Extracts/metabolism ; STAT1 Transcription Factor ; Signal Transduction ; Skin ; Tumor Necrosis Factor-alpha/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 6 6.

Tytuł :: L-arginine effect on inflammatory mediators: A systematic review of randomized controlled clinical trials.
Autorzy :: Mirhafez SR; Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Hariri M; Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.; Pokaż więcej
Źródło :: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition [Int J Vitam Nutr Res] 2021 Sep; Vol. 91 (5-6), pp. 562-570. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji :: Journal Article; Systematic Review
MeSH Terms :: Inflammation*/drug therapy
Inflammation Mediators*
Adult ; Arginine ; Biomarkers ; C-Reactive Protein/analysis ; Female ; Humans ; Interleukin-6 ; Male ; Randomized Controlled Trials as Topic ; Tumor Necrosis Factor-alpha
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options.
Autorzy :: Dyavar SR; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA. Electronic address: .
Singh R; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India.
Emani R; Buck Institute for Research on Ageing, Novato, CA, USA.
Pawar GP; Division of Medicinal Chemistry, CSIR-Institute of Microbiology Technology Chandigarh, Sector-39A, Chandigarh,160036, India.
Chaudhari VD; Division of Medicinal Chemistry, CSIR-Institute of Microbiology Technology Chandigarh, Sector-39A, Chandigarh,160036, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Podany AT; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
Avedissian SN; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
Fletcher CV; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
Salunke DB; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India; National Interdisciplinary Centre of Vaccine, Immunotherapeutics and Antimicrobials, Panjab University, Chandigarh, 160014, India. Electronic address: .; Pokaż więcej
Źródło :: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Sep; Vol. 141, pp. 111794. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :: Journal Article; Review
MeSH Terms :: COVID-19/*metabolism
Inflammation Mediators/*metabolism
Interferons/*metabolism
Signal Transduction/*physiology
Toll-Like Receptor 7/*physiology
Toll-Like Receptor 8/*physiology
Anti-Inflammatory Agents/administration & dosage ; COVID-19/immunology ; COVID-19/therapy ; Humans ; Inflammation Mediators/immunology ; Interferons/immunology ; Toll-Like Receptor 7/agonists ; Toll-Like Receptor 8/agonists
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome.
Autorzy :: Wang WT; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.
He M; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.
Shimizu C; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.
Croker BA; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.
Hoffman HM; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Tremoulet AH; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Burns JC; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Shyy JY; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.; Pokaż więcej
Źródło :: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. 2509-2511. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :: Comparative Study; Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: COVID-19/*immunology
Granulocytes/*immunology
Inflammasomes/*immunology
Inflammation Mediators/*immunology
Mucocutaneous Lymph Node Syndrome/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*immunology
Neutrophils/*immunology
Systemic Inflammatory Response Syndrome/*immunology
Adaptor Proteins, Signal Transducing/blood ; Adaptor Proteins, Signal Transducing/genetics ; COVID-19/blood ; COVID-19/genetics ; Caspase 1/blood ; Caspase 1/genetics ; Caspases, Initiator/blood ; Caspases, Initiator/genetics ; Gene Expression Profiling ; Granulocytes/metabolism ; Humans ; Inflammasomes/genetics ; Inflammasomes/metabolism ; Inflammation Mediators/blood ; Interleukin-1beta/blood ; Interleukin-1beta/genetics ; Mucocutaneous Lymph Node Syndrome/blood ; Mucocutaneous Lymph Node Syndrome/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neutrophils/metabolism ; Systemic Inflammatory Response Syndrome/blood ; Systemic Inflammatory Response Syndrome/genetics ; Transcriptome
SCR Disease Name :: pediatric multisystem inflammatory disease, COVID-19 related
: Raport

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Interplay between inflammation and thrombosis in cardiovascular pathology.
Autorzy :: Stark K; Medizinische Klinik und Poliklinik I, University Hospital, LMU Munich, Munich, Germany. .; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany. .; Walter-Brendel Center of Experimental Medicine, Faculty of Medicine, LMU Munich, Munich, Germany. .
Massberg S; Medizinische Klinik und Poliklinik I, University Hospital, LMU Munich, Munich, Germany. .; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany. .; Walter-Brendel Center of Experimental Medicine, Faculty of Medicine, LMU Munich, Munich, Germany. .; Pokaż więcej
Źródło :: Nature reviews. Cardiology [Nat Rev Cardiol] 2021 Sep; Vol. 18 (9), pp. 666-682. Date of Electronic Publication: 2021 May 06.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Anti-Inflammatory Agents/*therapeutic use
Blood Coagulation/*drug effects
Fibrinolytic Agents/*therapeutic use
Immune System/*drug effects
Inflammation/*drug therapy
Inflammation Mediators/*antagonists & inhibitors
Thrombosis/*prevention & control
Anti-Inflammatory Agents/adverse effects ; COVID-19/blood ; COVID-19/immunology ; Fibrinolytic Agents/adverse effects ; Humans ; Immune System/immunology ; Immune System/metabolism ; Inflammation/blood ; Inflammation/immunology ; Inflammation Mediators/metabolism ; Risk Assessment ; Risk Factors ; Signal Transduction ; Thrombosis/blood ; Thrombosis/immunology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines.
Autorzy :: Afsar T; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. .
Razak S; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. .
Aldisi D; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Shabbir M; Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan.
Almajwal A; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Al Kheraif AA; Dental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Arshad M; Dental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.; Pokaż więcej
Źródło :: Scientific reports [Sci Rep] 2021 Aug 26; Vol. 11 (1), pp. 17248. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Acacia/*chemistry
Acetates/*chemistry
Acute Kidney Injury/*prevention & control
Cytokines/*antagonists & inhibitors
Inflammation Mediators/*antagonists & inhibitors
Plant Extracts/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/metabolism ; Animals ; Cisplatin ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Cytokines/metabolism ; Disease Models, Animal ; HCT116 Cells ; Humans ; Inflammation Mediators/metabolism ; Male ; Mice, Nude ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays/methods
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 11 11.

Tytuł :: Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.
Autorzy :: Fang H; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Centre for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiang L; Bristol Renal Unit, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.; Pokaż więcej
Źródło :: Frontiers in immunology [Front Immunol] 2021 Aug 20; Vol. 12, pp. 687291. Date of Electronic Publication: 2021 Aug 20 (Print Publication: 2021).
Typ publikacji :: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Drug Repositioning*
Gene Regulatory Networks*
Anti-Inflammatory Agents/*therapeutic use
Immunity, Innate/*drug effects
Inflammation/*drug therapy
Inflammation Mediators/*antagonists & inhibitors
Kidney Calculi/*drug therapy
Databases, Genetic ; Genome-Wide Association Study ; Humans ; Immunity, Innate/genetics ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Kidney Calculi/genetics ; Kidney Calculi/immunology ; Kidney Calculi/metabolism ; Molecular Targeted Therapy ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Signal Transduction
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: DAMPening COVID-19 Severity by Attenuating Danger Signals.
Autorzy :: Silva-Lagos LA; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen (UMCG), Groningen, Netherlands.
Pillay J; Department of Intensive Care, University Medical Center Groningen (UMCG), University of Groningen, Groningen, Netherlands.
van Meurs M; Department of Intensive Care, University Medical Center Groningen (UMCG), University of Groningen, Groningen, Netherlands.
Smink A; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen (UMCG), Groningen, Netherlands.
van der Voort PHJ; Department of Intensive Care, University Medical Center Groningen (UMCG), University of Groningen, Groningen, Netherlands.
de Vos P; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen (UMCG), Groningen, Netherlands.; Pokaż więcej
Źródło :: Frontiers in immunology [Front Immunol] 2021 Aug 12; Vol. 12, pp. 720192. Date of Electronic Publication: 2021 Aug 12 (Print Publication: 2021).
Typ publikacji :: Journal Article; Review
MeSH Terms :: Alarmins/*immunology
COVID-19/*physiopathology
Inflammation Mediators/*immunology
Adenosine/metabolism ; Alarmins/antagonists & inhibitors ; Animals ; COVID-19/complications ; COVID-19/immunology ; COVID-19/therapy ; Humans ; Inflammation/prevention & control ; Inflammation Mediators/antagonists & inhibitors ; Multiple Organ Failure/etiology ; Multiple Organ Failure/prevention & control ; Patient Acuity ; Signal Transduction ; Toll-Like Receptors/antagonists & inhibitors ; Toll-Like Receptors/immunology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: [Myokines and adipomyokines: inflammatory mediators or unique molecules of targeted therapy for obesity?]
Autorzy :: Vasyukova OV; Endocrinology Research Center.
Kasyanova YV; Endocrinology Research Center.
Okorokov PL; Endocrinology Research Center.
Bezlepkina OB; Endocrinology Research Center.; Pokaż więcej
Źródło :: Problemy endokrinologii [Probl Endokrinol (Mosk)] 2021 Aug 10; Vol. 67 (4), pp. 36-45. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :: Journal Article
MeSH Terms :: Inflammation Mediators*
Obesity*/drug therapy
Adipose Tissue ; Child ; Exercise ; Humans ; Muscle, Skeletal
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Liver inflammation at the time of spinal cord injury enhances intraspinal pathology, liver injury, metabolic syndrome and locomotor deficits.
Autorzy :: Goodus MT; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neuroscience, College of Medicine, Ohio State University, Columbus, OH, USA.
Carson KE; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neuroscience, College of Medicine, Ohio State University, Columbus, OH, USA.
Sauerbeck AD; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neurology, Washington University in St. Louis, Missouri, USA.
Dey P; Department of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.
Alfredo AN; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neuroscience, College of Medicine, Ohio State University, Columbus, OH, USA.
Popovich PG; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neuroscience, College of Medicine, Ohio State University, Columbus, OH, USA.
Bruno RS; Department of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, OH, USA.
McTigue DM; The Belford Center for Spinal Cord Injury, Ohio State University, Columbus, OH, USA; Department of Neuroscience, College of Medicine, Ohio State University, Columbus, OH, USA. Electronic address: .; Pokaż więcej
Źródło :: Experimental neurology [Exp Neurol] 2021 Aug; Vol. 342, pp. 113725. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Inflammation Mediators*/metabolism
Fatty Liver/*pathology
Locomotion/*physiology
Metabolic Syndrome/*pathology
Spinal Cord Injuries/*pathology
Animals ; Fatty Liver/metabolism ; Female ; Hepatitis/metabolism ; Hepatitis/pathology ; Metabolic Syndrome/metabolism ; Rats ; Rats, Sprague-Dawley ; Spinal Cord Injuries/metabolism ; Thoracic Vertebrae/injuries
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Targeting Inflammasomes to Treat Neurological Diseases.
Autorzy :: Lünemann JD; Department of Neurology and Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
Malhotra S; Department of Neurology-Neuroimmunology, Multiple Sclerosis Center of Catalonia, Vall d'Hebron University Hospital, Barcelona, Spain.
Shinohara ML; Department of Immunology, Duke University School of Medicine, Durham, NC.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC.
Montalban X; Department of Neurology-Neuroimmunology, Multiple Sclerosis Center of Catalonia, Vall d'Hebron University Hospital, Barcelona, Spain.
Comabella M; Department of Neurology-Neuroimmunology, Multiple Sclerosis Center of Catalonia, Vall d'Hebron University Hospital, Barcelona, Spain.; Pokaż więcej
Źródło :: Annals of neurology [Ann Neurol] 2021 Aug; Vol. 90 (2), pp. 177-188. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Drug Delivery Systems/*methods
Inflammasomes/*antagonists & inhibitors
Inflammation Mediators/*antagonists & inhibitors
Nervous System Diseases/*drug therapy
Animals ; Anti-Inflammatory Agents/administration & dosage ; Drug Delivery Systems/trends ; Humans ; Inflammasomes/metabolism ; Inflammation Mediators/metabolism ; Nervous System Diseases/metabolism ; Treatment Outcome
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Neuropathophysiology of coronavirus disease 2019: neuroinflammation and blood brain barrier disruption are critical pathophysiological processes that contribute to the clinical symptoms of SARS-CoV-2 infection.
Autorzy :: Welcome MO; Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Nile University of Nigeria, Plot 681 Cadastral Zone, C-00 Research and Institution Area, Jabi Airport Road Bypass, FCT, Abuja, Nigeria. .
Mastorakis NE; Technical University of Sofia, Klement Ohridksi 8, 1000, Sofia, Bulgaria.; Pokaż więcej
Źródło :: Inflammopharmacology [Inflammopharmacology] 2021 Aug; Vol. 29 (4), pp. 939-963. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Blood-Brain Barrier/*metabolism
Brain/*metabolism
COVID-19/*metabolism
Inflammation Mediators/*metabolism
SARS-CoV-2/*metabolism
Blood-Brain Barrier/immunology ; Blood-Brain Barrier/pathology ; Brain/immunology ; Brain/pathology ; COVID-19/immunology ; COVID-19/pathology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/metabolism ; Cytokine Release Syndrome/pathology ; Humans ; Inflammation Mediators/immunology ; SARS-CoV-2/immunology ; Signal Transduction/physiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Bulbocodin D ameliorate cognitive impairment in APP/PS1 transgenic mice by modulating amyloid-beta burden, oxidative status and neuroinflammation.
Autorzy :: Hao F; Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, 110122, Liaoning, China.
Feng Y; Department of Ultrasound, The First Affiliated Hospital of China Medical University, Shenyang, 110001, Liaoning, China. .; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2021 Aug; Vol. 238 (8), pp. 2073-2082. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :: Journal Article
MeSH Terms :: Amyloid beta-Peptides/*antagonists & inhibitors
Antioxidants/*therapeutic use
Cognitive Dysfunction/*drug therapy
Inflammation Mediators/*antagonists & inhibitors
Oxidative Stress/*drug effects
Plaque, Amyloid/*drug therapy
Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/genetics ; Animals ; Antioxidants/pharmacology ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/pathology ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microglia/drug effects ; Microglia/metabolism ; Oxidative Stress/physiology ; Plaque, Amyloid/genetics ; Plaque, Amyloid/metabolism ; Presenilin-1/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Anti-Inflammatory Potential Exhibited by Amomum subulatum Fruits Mitigates Experimentally Induced Acute and Chronic Inflammation in Mice: Evaluation of Antioxidant Parameters, Pro-Inflammatory Mediators and HO-1 Pathway.
Autorzy :: Drishya S; Laboratory of Immunopharmacology and Experimental Therapeutics, Division of Cancer Research, Regional Cancer Centre, Medical College Campus, Thiruvananthapuram, India (Research Centre, University of Kerala).
Dhanisha SS; Laboratory of Immunopharmacology and Experimental Therapeutics, Division of Cancer Research, Regional Cancer Centre, Medical College Campus, Thiruvananthapuram, India (Research Centre, University of Kerala).
Guruvayoorappan C; Laboratory of Immunopharmacology and Experimental Therapeutics, Division of Cancer Research, Regional Cancer Centre, Medical College Campus, Thiruvananthapuram, India (Research Centre, University of Kerala).; Pokaż więcej
Źródło :: Journal of the American College of Nutrition [J Am Coll Nutr] 2021 Aug; Vol. 40 (6), pp. 551-561. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Amomum*
Inflammation Mediators*
Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antioxidants/pharmacology ; Fruit ; Heme Oxygenase-1/therapeutic use ; Inflammation/chemically induced ; Inflammation/drug therapy ; Mice ; Nitric Oxide ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Inflammatory profile in a canine model of hypothermic circulatory arrest.
Autorzy :: Giuliano K; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: .
Torres-Odio S; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland; Current affilitation: Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, TX 77843.
Etchill E; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Carr P; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland.
Conover Talbot C Jr; Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Blue ME; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johnston MV; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Baumgartner WA; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Lawton JS; Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Wilson MA; Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Pokaż więcej
Źródło :: The Journal of surgical research [J Surg Res] 2021 Aug; Vol. 264, pp. 260-273. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Brain Ischemia/*immunology
Circulatory Arrest, Deep Hypothermia Induced/*adverse effects
Cytokines/*metabolism
Inflammation Mediators/*metabolism
Animals ; Biomarkers/cerebrospinal fluid ; Biomarkers/metabolism ; Brain/blood supply ; Brain/immunology ; Brain/pathology ; Brain Ischemia/cerebrospinal fluid ; Brain Ischemia/diagnosis ; Brain Ischemia/pathology ; Cytokines/cerebrospinal fluid ; Disease Models, Animal ; Dogs ; Gene Expression Profiling ; Humans ; Inflammation Mediators/cerebrospinal fluid ; Male
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation.
Autorzy :: Shi Q; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Hu B; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Yang C; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Deng S; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Cheng X; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Wu J; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
Qi N; Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. Electronic address: .; Pokaż więcej
Źródło :: Toxicology [Toxicology] 2021 Aug; Vol. 460, pp. 152890. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Activating Transcription Factor 3/*deficiency
Arsenic/*toxicity
Bronchi/*metabolism
Inflammation Mediators/*metabolism
Lung Neoplasms/*metabolism
Respiratory Mucosa/*metabolism
Activating Transcription Factor 3/genetics ; Animals ; Cell Line, Transformed ; Female ; Gene Knockout Techniques/methods ; HEK293 Cells ; Humans ; Inflammation Mediators/antagonists & inhibitors ; Lung Neoplasms/chemically induced ; Lung Neoplasms/prevention & control ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Xenograft Model Antitumor Assays/methods
: Czasopismo naukowe

Szczegóły

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