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    Wyświetlanie 1-11 z 11
    Tytuł:
    A comprehensive analysis of breast cancer microbiota and host gene expression.
    Autorzy:
    Thompson KJ; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Ingle JN; Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Tang X; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Chia N; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
    Jeraldo PR; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
    Walther-Antonio MR; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
    Kandimalla KK; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN, United States of America.
    Johnson S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Yao JZ; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Harrington SC; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Suman VJ; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
    Wang L; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Weinshilboum RL; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Boughey JC; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
    Kocher JP; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
    Nelson H; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
    Goetz MP; Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Kalari KR; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
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    Źródło:
    PloS one [PLoS One] 2017 Nov 30; Vol. 12 (11), pp. e0188873. Date of Electronic Publication: 2017 Nov 30 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression*
    Breast Neoplasms/*microbiology
    Breast Neoplasms/genetics ; Breast Neoplasms/immunology ; Breast Neoplasms/pathology ; Female ; Humans ; Proteobacteria ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, RNA ; Tumor Microenvironment
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.
    Autorzy:
    Cairns J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Ingle JN; Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Wickerham LD; Section of Cancer Genetics and Prevention, Allegheny General Hospital, Pittsburgh, Pennsylvania, United States of America.; National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, Pennsylvania, United States of America.
    Weinshilboum R; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Liu M; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Wang L; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
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    Źródło:
    PLoS genetics [PLoS Genet] 2017 Oct 02; Vol. 13 (10), pp. e1007031. Date of Electronic Publication: 2017 Oct 02 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    BRCA1 Protein/*metabolism
    Breast Neoplasms/*genetics
    Cathepsins/*genetics
    DNA-Binding Proteins/*genetics
    BRCA1 Protein/genetics ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cysteine Proteases/genetics ; Cysteine Proteases/metabolism ; Drug Resistance, Neoplasm/genetics ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Genetic Markers ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide ; Proteins ; Quantitative Trait Loci ; Tamoxifen/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer.
    Autorzy:
    Reese JM
    Suman VJ
    Subramaniam M
    Wu X
    Negron V
    Gingery A
    Pitel KS
    Shah SS
    Cunliffe HE
    McCullough AE
    Pockaj BA
    Couch FJ
    Olson JE
    Reynolds C
    Lingle WL
    Spelsberg TC
    Goetz MP
    Ingle JN
    Hawse JR; Department of Biochemistry and Molecular Biology, Mayo Clinic, 16-01B Guggenheim Building, 200 First St, SW, Rochester, MN 55905, USA. .
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    Źródło:
    BMC cancer [BMC Cancer] 2014 Oct 07; Vol. 14, pp. 749. Date of Electronic Publication: 2014 Oct 07.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Breast Neoplasms/*metabolism
    Breast Neoplasms/*pathology
    Estrogen Antagonists/*pharmacology
    Estrogen Receptor beta/*metabolism
    Tamoxifen/*pharmacology
    Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal/metabolism ; Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; Estrogen Receptor alpha/antagonists & inhibitors ; Estrogen Receptor beta/antagonists & inhibitors ; Estrogen Receptor beta/genetics ; Female ; Humans ; MCF-7 Cells ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeleton.
    Autorzy:
    Gingery A; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Subramaniam M; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Pitel KS; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Reese JM; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.
    Cicek M; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Lindenmaier LB; Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America.
    Ingle JN; Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Goetz MP; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America; Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Turner RT; Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America.
    Iwaniec UT; Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America.
    Spelsberg TC; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
    Hawse JR; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 May 22; Vol. 9 (5), pp. e98219. Date of Electronic Publication: 2014 May 22 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents, Hormonal/*therapeutic use
    Bone and Bones/*drug effects
    Breast Neoplasms/*drug therapy
    Tamoxifen/*analogs & derivatives
    Animals ; Antineoplastic Agents, Hormonal/pharmacology ; Base Sequence ; DNA Primers ; Female ; Mice ; Mice, Inbred C57BL ; Ovariectomy ; Polymerase Chain Reaction ; Tamoxifen/pharmacology ; Tamoxifen/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells.
    Autorzy:
    Opyrchal M; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Salisbury JL; Department of Biochemistry and Molecular Biology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Zhang S; Department of Biochemistry and Molecular Biology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    McCubrey J; Department of Microbiology and Immunology, East Carolina University, Greenville, North Carolina, United States of America.
    Hawse J; Department of Biochemistry and Molecular Biology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Goetz MP; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Lomberk GA; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Haddad T; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Degnim A; Department of General Surgery, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Lange C; Departments of Medicine and Pharmacology, University of Minnesota, Minneapolis, Minnesota, United States of America.
    Ingle JN; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    Galanis E; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America; Department of Molecular Medicine, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
    D'Assoro AB; Department of Medical Oncology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America; Department of Biochemistry and Molecular Biology, Mayo Clinic College Of Medicine, Rochester, Minnesota, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 May 09; Vol. 9 (5), pp. e96995. Date of Electronic Publication: 2014 May 09 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Drug Resistance, Neoplasm*
    Aurora Kinase A/*metabolism
    Breast Neoplasms/*metabolism
    Breast Neoplasms/*pathology
    Down-Regulation/*drug effects
    Estrogen Receptor alpha/*metabolism
    Hormones/*pharmacology
    Animals ; Breast Neoplasms/enzymology ; Disease Progression ; Female ; Humans ; MCF-7 Cells ; Mice ; Smad5 Protein/metabolism ; Xenograft Model Antitumor Assays
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Pharmacogenomics of endocrine therapy in breast cancer.
    Autorzy:
    Ingle JN; Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA. Ingle.james@mayo.edu
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    Źródło:
    Journal of human genetics [J Hum Genet] 2013 Jun; Vol. 58 (6), pp. 306-12. Date of Electronic Publication: 2013 May 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Breast Neoplasms/*drug therapy
    Pharmacogenetics/*methods
    Selective Estrogen Receptor Modulators/*therapeutic use
    Anastrozole ; Androstadienes/therapeutic use ; Antineoplastic Agents, Hormonal/therapeutic use ; Aromatase Inhibitors/therapeutic use ; Breast Neoplasms/genetics ; Chemotherapy, Adjuvant ; Female ; Genome-Wide Association Study ; Humans ; Japan ; Letrozole ; Musculoskeletal Physiological Phenomena/drug effects ; Nitriles/therapeutic use ; Phenotype ; Postmenopause ; Raloxifene Hydrochloride/therapeutic use ; Randomized Controlled Trials as Topic ; Tamoxifen/therapeutic use ; Triazoles/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-11 z 11

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