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Tytuł:
Hyperglycemic Stress Induces Expression, Degradation, and Nuclear Association of Rho GDP Dissociation Inhibitor 2 (RhoGDIβ) in Pancreatic β-Cells.
Autorzy:
Gleason N; Research Service, John D. Dingell VA Medical Center, Detroit, MI 48201, USA.; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Kowluru A; Research Service, John D. Dingell VA Medical Center, Detroit, MI 48201, USA.; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
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Źródło:
Cells [Cells] 2024 Feb 01; Vol. 13 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin-Secreting Cells*/metabolism
rho Guanine Nucleotide Dissociation Inhibitor beta*/metabolism
Animals ; Humans ; Rats ; GTP-Binding Proteins/metabolism ; rho Guanine Nucleotide Dissociation Inhibitor alpha/metabolism ; rho Guanine Nucleotide Dissociation Inhibitor gamma/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Serum levels of matrix metalloproteinases 1, 2, and 7, and their tissue inhibitors 1, 2, 3, and 4 in polytraumatized patients: Time trajectories, correlations, and their ability to predict mortality.
Autorzy:
Negrin LL; University Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria.
Carlin GL; University Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria.; University Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
Ristl R; Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Hajdu S; University Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria.
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Źródło:
PloS one [PLoS One] 2024 Mar 08; Vol. 19 (3), pp. e0300258. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Tissue Inhibitor of Metalloproteinases*/metabolism
Multiple Trauma*
Humans ; Adult ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 7 ; Matrix Metalloproteinase 1/metabolism ; Matrix Metalloproteinases/metabolism ; Tissue Inhibitor of Metalloproteinase-1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effect of Xevinapant Combined with Ionizing Radiation on HNSCC and Normal Tissue Cells and the Impact of Xevinapant on Its Targeted Proteins cIAP1 and XIAP.
Autorzy:
Fleischmann J; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nürnberg (CCC ER-EMN), 91054 Erlangen, Germany.
Hildebrand LS; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nürnberg (CCC ER-EMN), 91054 Erlangen, Germany.
Kuhlmann L; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nürnberg (CCC ER-EMN), 91054 Erlangen, Germany.
Fietkau R; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nürnberg (CCC ER-EMN), 91054 Erlangen, Germany.
Distel LV; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nürnberg (CCC ER-EMN), 91054 Erlangen, Germany.
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Źródło:
Cells [Cells] 2023 Jun 17; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents*/pharmacology
Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/radiotherapy
Radiation-Sensitizing Agents*/pharmacology
Squamous Cell Carcinoma of Head and Neck*/drug therapy
Squamous Cell Carcinoma of Head and Neck*/radiotherapy
Inhibitor of Apoptosis Proteins*/antagonists & inhibitors
Inhibitor of Apoptosis Proteins*/metabolism
Humans ; Radiation, Ionizing ; X-Linked Inhibitor of Apoptosis Protein/antagonists & inhibitors ; X-Linked Inhibitor of Apoptosis Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Systematic Review on the Role of Matrix Metalloproteinases in the Pathogenesis of Inguinal Hernias.
Autorzy:
Bracale U; Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Peltrini R; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Iacone B; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Martirani M; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Sannino D; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Gargiulo A; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Corcione F; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Serra R; Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Bracale UM; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 Jul 14; Vol. 13 (7). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-1*/genetics
Hernia, Inguinal*
Humans ; Tissue Inhibitor of Metalloproteinase-2 ; Matrix Metalloproteinase 2 ; Prospective Studies ; Tissue Inhibitor of Metalloproteinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) and Pulmonary Involvement in COVID-19 Pneumonia.
Autorzy:
Zingaropoli MA; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Latronico T; Department of Biosciences, Biotechnologies and Environment, University of Bari 'Aldo Moro', 70121 Bari, Italy.
Pasculli P; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Masci GM; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Merz R; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Ciccone F; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Dominelli F; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Del Borgo C; Infectious Diseases Unit, Santa Maria Goretti Hospital, Sapienza, University of Rome, 04100 Latina, Italy.
Lichtner M; Infectious Diseases Unit, Santa Maria Goretti Hospital, Sapienza, University of Rome, 04100 Latina, Italy.; Department of Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome, 00161 Rome, Italy.
Iafrate F; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Galardo G; Medical Emergency Unit, Sapienza University of Rome, Policlinico Umberto I, 00161 Rome, Italy.
Pugliese F; Department of Specialist Surgery and Organ Transplantation 'Paride Stefanini', Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Panebianco V; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Ricci P; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.; Unit of Emergency Radiology, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Catalano C; Department of Radiological, Oncological and Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Ciardi MR; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Liuzzi GM; Department of Biosciences, Biotechnologies and Environment, University of Bari 'Aldo Moro', 70121 Bari, Italy.
Mastroianni CM; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 Jun 26; Vol. 13 (7). Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-1*
COVID-19*
Humans ; Matrix Metalloproteinase 9 ; Matrix Metalloproteinase 2 ; Tissue Inhibitor of Metalloproteinase-2 ; Matrix Metalloproteinase 1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14.
Autorzy:
Hayun H; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, P.O.B. 653, 84105, Beer-Sheva, Israel.
Coban M; Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, 310 Griffin Building, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Bhagat AK; Department of Life Sciences and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.; Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.
Ozer E; Department of Life Sciences and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.; Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.
Alfonta L; Department of Life Sciences and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.; Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, 8410501, Beer-Sheva, Israel.
Caulfield TR; Departments of Neuroscience, Artificial Intelligence and Informatics, Computational Biology and Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Jacksonville, FL, 32224, USA. .
Radisky ES; Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, 310 Griffin Building, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. .
Papo N; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, P.O.B. 653, 84105, Beer-Sheva, Israel. .
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 30; Vol. 13 (1), pp. 5186. Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-2*/genetics
Tissue Inhibitor of Metalloproteinase-2*/metabolism
Matrix Metalloproteinase 2*/genetics
Matrix Metalloproteinase 2*/metabolism
Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 14 ; Levodopa ; Tissue Inhibitor of Metalloproteinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Autorzy:
Dietz L; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Ellison CJ; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Riechmann C; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Cassidy CK; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Felfoldi FD; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
Pinto-Fernández A; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Kessler BM; Target Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, OX3 7FZ, UK.; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Elliott PR; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Mar 17; Vol. 379 (6637), pp. 1112-1117. Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Caspase 3*/metabolism
Caspase 7*/metabolism
Caspase 9*/metabolism
Inhibitor of Apoptosis Proteins*/chemistry
Inhibitor of Apoptosis Proteins*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Humans ; Cryoelectron Microscopy ; X-Linked Inhibitor of Apoptosis Protein/metabolism ; Catalytic Domain ; Protein Multimerization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro.
Autorzy:
Brauer E; Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Lange T; Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Keller D; Institute for Medical Genetics and Human Genetics, Charité - Universtitätsmedizin Berlin, Berlin, Germany.
Görlitz S; Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Cho S; Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Keye J; Flow & Mass Cytometry Core Facility, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Gossen M; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Institute of Active Polymers, Helmholtz-Zentrum Hereon, Teltow, Germany.
Petersen A; Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Kornak U; Institute for Medical Genetics and Human Genetics, Charité - Universtitätsmedizin Berlin, Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany.
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Źródło:
Aging cell [Aging Cell] 2023 Mar; Vol. 22 (3), pp. e13744. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cellular Senescence*
Cyclin-Dependent Kinase Inhibitor p16*/metabolism
Humans ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Cell Proliferation ; Extracellular Matrix/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Knocking Down CDKN2A in 3D hiPSC-Derived Brown Adipose Progenitors Potentiates Differentiation, Oxidative Metabolism and Browning Process.
Autorzy:
Kahoul Y; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Yao X; Faculté de Médecine, CNRS, INSERM, iBV, Université Côte d'Azur, CEDEX 2, F-06107 Nice, France.
Oger F; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Moreno M; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Amanzougarene S; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Derhourhi M; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Durand E; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Boutry R; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
Bonnefond A; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.; Department of Metabolism, Imperial College London, London SW7 2BX, UK.
Froguel P; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.; Department of Metabolism, Imperial College London, London SW7 2BX, UK.
Dani C; Faculté de Médecine, CNRS, INSERM, iBV, Université Côte d'Azur, CEDEX 2, F-06107 Nice, France.
Annicotte JS; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement, F-59000 Lille, France.
Breton C; Univ. Lille, INSERM, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR8199-EGID, F-59000 Lille, France.
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Źródło:
Cells [Cells] 2023 Mar 10; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cyclin-Dependent Kinase Inhibitor p16*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Humans ; Adipocytes, Brown/metabolism ; Cell Differentiation ; Cyclin-Dependent Kinase Inhibitor Proteins ; Obesity/metabolism ; Oxidative Stress
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Decreased ratios of matrix metalloproteinases to tissue-type inhibitors in cerebrospinal fluid in sporadic and hereditary cerebral amyloid angiopathy.
Autorzy:
Vervuurt M; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
de Kort AM; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Jäkel L; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Kersten I; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Abdo WF; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Schreuder FHBM; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Rasing I; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Terwindt GM; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Wermer MJH; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Greenberg SM; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Klijn CJM; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Kuiperij HB; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands.
Verbeek MM; Department of Neurology, Cognition and Behaviour, Donders Institute for Brain, Radboud University Medical Center, P.O. Box 9101, 6500 HB , 830 TML, Nijmegen, The Netherlands. .; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2023 Jan 30; Vol. 15 (1), pp. 26. Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-2*
Cerebral Amyloid Angiopathy, Familial*
Humans ; Tissue Inhibitor of Metalloproteinase-1 ; Matrix Metalloproteinase 14 ; Matrix Metalloproteinase 2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blood-Brain Barrier-Associated Proteins Are Elevated in Serum of Epilepsy Patients.
Autorzy:
Bronisz E; Second Department of Neurology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
Cudna A; Second Department of Neurology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
Wierzbicka A; Sleep Disorders Center, Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
Kurkowska-Jastrzębska I; Sleep Disorders Center, Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
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Źródło:
Cells [Cells] 2023 Jan 19; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-1*
Epilepsy*
Humans ; Blood-Brain Barrier ; Matrix Metalloproteinase 9 ; Tissue Inhibitor of Metalloproteinase-2 ; Matrix Metalloproteinase 2 ; P-Selectin ; Intercellular Adhesion Molecule-1 ; Seizures
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs.
Autorzy:
Costanzo L; Department of Medicine, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Soto B; Department of Medicine, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Meier R; Department of Medicine, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Geraghty P; Department of Medicine, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
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Źródło:
Pulmonary medicine [Pulm Med] 2022 Dec 31; Vol. 2022, pp. 3632764. Date of Electronic Publication: 2022 Dec 31 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-2*/metabolism
Matrix Metalloproteinase 2*/metabolism
Humans ; Tissue Inhibitor of Metalloproteinases/metabolism ; Matrix Metalloproteinases/metabolism ; Lung/metabolism ; Biology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis.
Autorzy:
Ishii D; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Kawasaki T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Sato H; Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Tatsumi K; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Imamoto T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Yoshioka K; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Abe M; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Hasegawa Y; Department of Applied Genomics, Kazusa DNA Research Institute, Chiba 292-0818, Japan.
Ohara O; Department of Applied Genomics, Kazusa DNA Research Institute, Chiba 292-0818, Japan.
Suzuki T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.; Synergy Institute for Futuristic Mucosal Vaccine Research and Development, Chiba University, Chiba 260-8670, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Plasminogen Activator Inhibitor 1*
Idiopathic Pulmonary Fibrosis*/drug therapy
Idiopathic Pulmonary Fibrosis*/genetics
Humans ; Leukocytes, Mononuclear ; Transcriptome ; Fatty Acids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Age-Related Changes in Clinical and Analytical Variables in Chronic Hemodialyzed Patients.
Autorzy:
Belo L; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Valente MJ; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; National Food Institute, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Rocha S; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Coimbra S; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; 1H-TOXRUN-One Health Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.
Catarino C; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Lousa I; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Bronze-da-Rocha E; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Rocha-Pereira P; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal.
Sameiro-Faria MD; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Hemodialysis Clinic of Felgueiras (CHF), 4610-106 Felgueiras, Portugal.
Oliveira JG; Hemodialysis Clinic of Porto (CHP), 4200-277 Porto, Portugal.; Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Madureira J; NefroServe Hemodialysis Clinic of Barcelos, 4750-110 Barcelos, Portugal.
Fernandes JC; NefroServe Hemodialysis Clinic of Viana do Castelo, 4901-858 Viana do Castelo, Portugal.
Miranda V; Hemodialysis Clinic of Gondomar, CHD, 4420-086 Gondomar, Portugal.
Nunes JPL; Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Santos-Silva A; UCIBIO-Applied Molecular Biosciences Unit, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 15; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-1*
Kidney Failure, Chronic*/complications
Adult ; Humans ; Aged ; Cross-Sectional Studies ; Renal Dialysis ; Biomarkers ; Phosphorus
Czasopismo naukowe
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Tytuł:
Elemental sulfur concentration can be used as a rapid, reliable, and cost-effective predictor of sulfur amino acid content of soybean seeds.
Autorzy:
Kim W; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA.
Kim S; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA.
Mawhinney TP; Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA.
Krishnan HB; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA. .; Plant Genetics Research Unit, USDA, Agricultural Research Service, University of Missouri, 108 Curtis Hall, Columbia, MO, 65211, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3093. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Trypsin Inhibitor, Bowman-Birk Soybean*/chemistry
Amino Acids, Sulfur*/metabolism
Glycine max ; Cysteine/metabolism ; Cost-Benefit Analysis ; Methionine/metabolism ; Seeds/metabolism ; Protease Inhibitors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of matrix metalloproteinases in mitral valve regurgitation: Association between the of MMP-1, MMP-9, TIMP-1, and TIMP-2 expression, degree of mitral valve insufficiency, and pathologic etiology.
Autorzy:
Shah HH; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Hussain MS; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Zehra SA; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
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Źródło:
Journal of cardiac surgery [J Card Surg] 2022 Oct; Vol. 37 (10), pp. 3446-3447. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Letter; Comment
MeSH Terms:
Mitral Valve Insufficiency*/etiology
Mitral Valve Insufficiency*/pathology
Tissue Inhibitor of Metalloproteinase-1*
Humans ; Matrix Metalloproteinase 1 ; Matrix Metalloproteinase 9 ; Matrix Metalloproteinases/metabolism ; Tissue Inhibitor of Metalloproteinase-2
Opinia redakcyjna
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Tytuł:
The role of the platelet pool of Plasminogen Activator Inhibitor-1 in well-controlled type 2 diabetes patients.
Autorzy:
Mossberg K; Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.; Department of Public Health and Community Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.
Olausson J; Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.; The Wallenberg Laboratory for Cardiovascular Research, Göteborg, Sweden.
Fryk E; Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.; The Wallenberg Laboratory for Cardiovascular Research, Göteborg, Sweden.
Jern S; Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.; The Wallenberg Laboratory for Cardiovascular Research, Göteborg, Sweden.
Jansson PA; Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.; The Wallenberg Laboratory for Cardiovascular Research, Göteborg, Sweden.
Brogren H; Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
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Źródło:
PloS one [PLoS One] 2022 Aug 31; Vol. 17 (8), pp. e0267833. Date of Electronic Publication: 2022 Aug 31 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Plasminogen Activator Inhibitor 1*/metabolism
Blood Platelets/metabolism ; Humans ; Obesity ; Plasminogen Activator Inhibitor 2/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Tissue Plasminogen Activator/metabolism
Czasopismo naukowe
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Tytuł:
Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.
Autorzy:
Chandra A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Lagnado AB; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Farr JN; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
Doolittle M; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
Robbins PD; Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Niedernhofer LJ; Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Ikeno Y; Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, San Antonio, Texas, USA.
Passos JF; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Monroe DG; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
Pignolo RJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
Khosla S; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.; Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.
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Źródło:
Aging cell [Aging Cell] 2022 May; Vol. 21 (5), pp. e13602. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cyclin-Dependent Kinase Inhibitor p16*/genetics
Cyclin-Dependent Kinase Inhibitor p16*/metabolism
Osteoporosis*/genetics
Adiposity ; Animals ; Bone Marrow/metabolism ; Cellular Senescence/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Mice ; Obesity
Czasopismo naukowe
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Tytuł:
The Predictive Role of MMP-2, MMP-9, TIMP-1 and TIMP-2 Serum Levels in the Complete Response of the Tumor to Chemotherapy in Breast Cancer Patients.
Autorzy:
Ozdemir K; Department of General Surgery, Sakarya University Research and Educational Hospital, Sakarya, Turkey.
Zengin I; Department of General Surgery, Sakarya University Research and Educational Hospital, Sakarya, Turkey.
Guney Eskiler G; Department of Medical Biology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Kocer HB; Department of General Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Ozkan AD; Department of Medical Biology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Demiray T; Department of Microbiology and Immunology, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
Sahin EO; Department of Microbiology and Immunology, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
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Źródło:
Journal of investigative surgery : the official journal of the Academy of Surgical Research [J Invest Surg] 2022 Jul; Vol. 35 (7), pp. 1544-1550. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Tissue Inhibitor of Metalloproteinase-1*/metabolism
Female ; Humans ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinases/metabolism ; Tissue Inhibitor of Metalloproteinase-2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Extracellular vesicles from periodontal pathogens regulate hepatic steatosis via Toll-like receptor 2 and plasminogen activator inhibitor-1.
Autorzy:
Kim HY; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Lim Y; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Jang JS; Department of Cell and Developmental Biology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Ko YK; Department of Immunology and Molecular Microbiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Choi Y; Department of Immunology and Molecular Microbiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Kim HH; Department of Cell and Developmental Biology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Choi BK; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jan; Vol. 13 (1), pp. e12407.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Non-alcoholic Fatty Liver Disease*
Plasminogen Activator Inhibitor 1*
Toll-Like Receptor 2*
Animals ; Humans ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 288035

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