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Tytuł :
Pharmacological studies of rhizomes of extract of Cyperus tegetum, emphasized on anticancer, anti-inflammatory and analgesic activity.
Autorzy :
Chatterjee A; Bengal School of Technology, Chinsurah, Hooghly, West Bengal, India. Electronic address: .
Khanra R; Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata, West Bengal, India. Electronic address: .
Chattopadhyay M; Maulana Abul Kalam Azad University of Technology, Bidhannagar, Kolkata, West Bengal, India. Electronic address: .
Ghosh S; Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata, West Bengal, India. Electronic address: .
Sahu R; Department of Pharmaceutical Technology, University of North Bengal, Darjeeling, India. Electronic address: .
Nandi G; Department of Pharmaceutical Technology, University of North Bengal, Darjeeling, India. Electronic address: .
Maji HS; Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata, West Bengal, India. Electronic address: .
Chakraborty P; Maulana Abul Kalam Azad University of Technology, Bidhannagar, Kolkata, West Bengal, India. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115035. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Cyperus/*chemistry
Plant Extracts/*pharmacology
Skin Neoplasms/*drug therapy
Analgesics/isolation & purification ; Analgesics/pharmacology ; Animals ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Female ; HeLa Cells ; Humans ; Inflammation/drug therapy ; Inflammation/pathology ; Inhibitory Concentration 50 ; Male ; Mice ; Rhizome ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Wound healing, anti-inflammatory and anti-melanogenic activities of ursane-type triterpenes from Semialarium mexicanum (Miers) Mennega.
Autorzy :
Apaza Ticona L; Organic Chemistry Unit, Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense of Madrid, Plza. Ramón y Cajal s/n, 28040, Madrid, Spain. Electronic address: .
Slowing K; Department of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense of Madrid, Plza. Ramón y Cajal s/n, 28040, Madrid, Spain.
Serban AM; Maria Sklodowska Curie University Hospital for Children. Constantin Brancoveanu Boulevard, 077120, Bucharest, Romania.
Humanes Bastante M; Department of Organic Chemistry, Faculty of Sciences, University Autónoma of Madrid. Cantoblanco, 28049, Madrid, Spain.
Hernáiz MJ; Organic Chemistry Unit, Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense of Madrid, Plza. Ramón y Cajal s/n, 28040, Madrid, Spain.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115009. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Celastraceae/*chemistry
Triterpenes/*pharmacology
Wound Healing/*drug effects
Animals ; Anti-Inflammatory Agents/isolation & purification ; Cell Line, Tumor ; Inhibitory Concentration 50 ; Medicine, Traditional ; Melanins/metabolism ; Melanoma, Experimental/metabolism ; Mice ; NIH 3T3 Cells ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; RAW 264.7 Cells ; Triterpenes/chemistry ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Investigation of the chemical structure of anti-amyloidogenic constituents extracted from Thamnolia vermicularis.
Autorzy :
Yu X; School of Life Science, Liaoning University, Shenyang, 110036, PR China; Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, PR China.
Cai Y; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Zhao X; Mathematical Computer Teaching and Research Office, Liaoning Vocational College of Medicine, Shenyang, 110101, PR China.
Wu C; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Liu J; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Niu T; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Shan X; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Lu Y; School of Life Science, Liaoning University, Shenyang, 110036, PR China.
Ruan Y; School of Life Science, Liaoning University, Shenyang, 110036, PR China. Electronic address: .
He J; School of Life Science, Liaoning University, Shenyang, 110036, PR China; Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115059. Date of Electronic Publication: 2022 Jan 31.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid/*drug effects
Ascomycota/*chemistry
Plant Extracts/*pharmacology
Amyloid/metabolism ; Animals ; Chromatography, Liquid ; Chromatography, Thin Layer ; Inhibitory Concentration 50 ; Mass Spectrometry ; Molecular Docking Simulation ; Muramidase ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Spectrometry, Fluorescence
SCR Organism :
Thamnolia vermicularis
Czasopismo naukowe
Tytuł :
Cytotoxic terpenoids from Tripterygium hypoglaucum against human pancreatic cancer cells SW1990 by increasing the expression of Bax protein.
Autorzy :
Chen XL; School of Chinese Materia Medica & Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan University of Chinese Medicine, Kunming, 650500, PR China.
Geng YJ; School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, 650500, PR China.
Li F; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, PR China.
Hu WY; School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, 650500, PR China. Electronic address: .
Zhang RP; School of Chinese Materia Medica & Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan University of Chinese Medicine, Kunming, 650500, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115010. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Pancreatic Neoplasms/*drug therapy
Terpenes/*pharmacology
Tripterygium/*chemistry
Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Inhibitory Concentration 50 ; Terpenes/administration & dosage ; Terpenes/isolation & purification ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł :
Numerical learning of deep features from drug-exposed cell images to calculate IC50 without staining.
Autorzy :
Cho K; Division of Electronics and Information System Research, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Techno-Jungangdaero 333, Daegu, 42988, Republic of Korea.
Choi ES; Division of Electronics and Information System Research, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Techno-Jungangdaero 333, Daegu, 42988, Republic of Korea.
Kim JH; Division of Electronics and Information System Research, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Techno-Jungangdaero 333, Daegu, 42988, Republic of Korea.
Son JW; Division of Electronics and Information System Research, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Techno-Jungangdaero 333, Daegu, 42988, Republic of Korea. .
Kim E; Division of Electronics and Information System Research, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Techno-Jungangdaero 333, Daegu, 42988, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2022 Apr 22; Vol. 12 (1), pp. 6610. Date of Electronic Publication: 2022 Apr 22.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Neural Networks, Computer*
Doxorubicin/pharmacology ; HEK293 Cells ; Humans ; Image Processing, Computer-Assisted/methods ; Inhibitory Concentration 50 ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium falciparum Isolates.
Autorzy :
Okitwi M; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Orena S; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Thomas K; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Tumwebaze PK; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Byaruhanga O; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Nsobya SL; Infectious Diseases Research Collaborationgrid.463352.5, Kampala, Uganda.
Conrad MD; Department of Medicine, University of California, San Franciscogrid.266102.1, California, USA.
Bayles BR; Department of Natural Sciences and Mathematics, Dominican University of Californiagrid.255148.f, San Rafael, California, USA.
Rosenthal PJ; Department of Medicine, University of California, San Franciscogrid.266102.1, California, USA.
Cooper RA; Department of Natural Sciences and Mathematics, Dominican University of Californiagrid.255148.f, San Rafael, California, USA.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Apr 19; Vol. 66 (4), pp. e0143721. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Malaria, Falciparum*/drug therapy
Drug Resistance ; Humans ; Inhibitory Concentration 50 ; Plasmodium falciparum ; Uganda
Czasopismo naukowe
Tytuł :
Ethnopharmacological nexus between the traditional Thai medicine theory and biologically based cancer treatment.
Autorzy :
Maki P; Student of Doctor of Philosophy (Applied Thai Traditional Medicine), Faculty of Medicine, Thammasat University (Rangsit Campus), Pathumthani, 12120, Thailand. Electronic address: .
Itharat A; Faculty of Medicine, Thammasat University (Rangsit Campus), Department of Applied Thai Traditional Medicine, Pathumthani, 12120, Thailand; Center of Excellence in Applied Thai Traditional Medicine Research, Thammasat University (Rangsit Campus), Pathumthani, 12120, Thailand. Electronic address: .
Thongdeeying P; Faculty of Medicine, Thammasat University (Rangsit Campus), Department of Applied Thai Traditional Medicine, Pathumthani, 12120, Thailand; Center of Excellence in Applied Thai Traditional Medicine Research, Thammasat University (Rangsit Campus), Pathumthani, 12120, Thailand. Electronic address: .
Tuy-On T; Center of Excellence in Applied Thai Traditional Medicine Research, Thammasat University (Rangsit Campus), Pathumthani, 12120, Thailand. Electronic address: .
Kuropakornpong P; Center of Excellence in Applied Thai Traditional Medicine Research, Thammasat University (Rangsit Campus), Pathumthani, 12120, Thailand. Electronic address: .
Pipatrattanaseree W; Regional Medical Science Center 12 Songkhla, Department of Medical Sciences, Ministry of Public Health, Songkhla, 90100, Thailand. Electronic address: .
Mingmalairak C; Faculty of Medicine, Thammasat University (Rangsit Campus), Department of Surgery and Research Group in Thai Herbs and Traditional Remedy for Cancer Patients, Pathumthani, 12120, Thailand. Electronic address: .
Davies NM; Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, Canada. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 Apr 06; Vol. 287, pp. 114932. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Liver Neoplasms/*drug therapy
Plant Extracts/*pharmacology
Plants, Medicinal/*chemistry
Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/isolation & purification ; Bile Duct Neoplasms/drug therapy ; Bile Duct Neoplasms/pathology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cholangiocarcinoma/drug therapy ; Cholangiocarcinoma/pathology ; Ethnopharmacology ; HaCaT Cells ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Liver Neoplasms/pathology ; Medicine, Traditional/methods ; Nitric Oxide/metabolism ; Plant Extracts/administration & dosage ; Thailand
Czasopismo naukowe
Tytuł :
Antiplasmodial diterpenoid alkaloid from Aconitum heterophyllum Wall. ex Royle: Isolation, characterization, and UHPLC-DAD based quantification.
Autorzy :
Anmol; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Kumari S; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Kumar R; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Wydział Chemii, Uniwersytet Wrocławski, 50-383, Wrocław, Poland.
Singh R; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Aggarwal G; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India.
Agrawal P; Malaria Drug Discovery Laboratory, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Sahal D; Malaria Drug Discovery Laboratory, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110067, India. Electronic address: .
Sharma U; Chemical Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 Apr 06; Vol. 287, pp. 114931. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Aconitum/*chemistry
Alkaloids/*pharmacology
Diterpenes/*pharmacology
Plasmodium falciparum/*drug effects
Alkaloids/administration & dosage ; Alkaloids/isolation & purification ; Antimalarials/administration & dosage ; Antimalarials/isolation & purification ; Antimalarials/pharmacology ; Chloroquine/pharmacology ; Chromatography, High Pressure Liquid ; Diterpenes/administration & dosage ; Diterpenes/isolation & purification ; Inhibitory Concentration 50 ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Roots
Czasopismo naukowe
Tytuł :
Anti-malarial activity in a Chinese herbal supplement containing Inonotus obliquus and Panax notoginseng.
Autorzy :
Endo T; Laboratory of Veterinary Infectious Diseases, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Nakagomi Y; Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Kawaguchi E; Laboratory of Veterinary Infectious Diseases, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Hayakawa ESH; Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, Tochigi 329-0498, Japan.
Vu HN; Department of Parasitology, Faculty of Veterinary Medicine, Viet Nam National University of Agriculture, Viet Nam.
Takemae H; Center for Infectious Disease Epidemiology and Prevention Research, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Shinohara Y; Iskra Industry Co., Ltd., Japan.
Yang D; Iskra Industry Co., Ltd., Japan.
Usui T; Laboratory of Veterinary Pharmacology, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Mizutani T; Center for Infectious Disease Epidemiology and Prevention Research, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Nakao Y; Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Furuya T; Laboratory of Veterinary Infectious Diseases, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan. Electronic address: .
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Źródło :
Parasitology international [Parasitol Int] 2022 Apr; Vol. 87, pp. 102532. Date of Electronic Publication: 2021 Dec 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*therapeutic use
Drugs, Chinese Herbal/*therapeutic use
Inonotus/*chemistry
Malaria, Falciparum/*drug therapy
Panax notoginseng/*chemistry
Plasmodium falciparum/*drug effects
Antimalarials/pharmacology ; Antimalarials/toxicity ; Artemisinins/pharmacology ; Artemisinins/therapeutic use ; Drug Resistance ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/toxicity ; HeLa Cells ; Humans ; Inhibitory Concentration 50 ; Japan
SCR Organism :
Inonotus obliquus
Czasopismo naukowe
Tytuł :
The role of Acanthamoeba castellanii (T4 genotype) antioxidant enzymes in parasite survival under H 2 O 2 -induced oxidative stress.
Autorzy :
Motavallihaghi S; Department of Medical Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Khodadadi I; Department of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: .
Goudarzi F; Regenerative Medicine Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Afshar S; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Shahbazi AE; School of Nursing and Midwifery, Saveh University of Medical Sciences, Saveh, Iran.
Maghsood AH; Department of Medical Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: .
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Źródło :
Parasitology international [Parasitol Int] 2022 Apr; Vol. 87, pp. 102523. Date of Electronic Publication: 2021 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Acanthamoeba castellanii/*enzymology
Antioxidants/*physiology
Hydrogen Peroxide/*adverse effects
Oxidative Stress/*physiology
Acanthamoeba castellanii/classification ; Acanthamoeba castellanii/genetics ; Acanthamoeba castellanii/metabolism ; Animals ; Antioxidants/metabolism ; Apoptosis ; Catalase/metabolism ; Cell Cycle ; Gene Expression Regulation, Enzymologic ; Genotype ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Glutathione Reductase/genetics ; Glutathione Reductase/metabolism ; Inhibitory Concentration 50 ; Oxidative Stress/drug effects ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Mechanisms of NMDA receptor inhibition by nafamostat, gabexate and furamidine.
Autorzy :
Zhigulin AS; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint-Petersburg, Russia.
Barygin OI; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint-Petersburg, Russia. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2022 Mar 15; Vol. 919, pp. 174795. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Serine Proteinase Inhibitors/*pharmacology
Animals ; Benzamidines/pharmacology ; Benzamidines/therapeutic use ; Drug Repositioning ; Esters/pharmacology ; Esters/therapeutic use ; Gabexate/pharmacology ; Gabexate/therapeutic use ; Guanidines/pharmacology ; Guanidines/therapeutic use ; Hippocampus/drug effects ; Inhibitory Concentration 50 ; Male ; Models, Animal ; Neurodegenerative Diseases/drug therapy ; Pyramidal Cells/drug effects ; Rats ; Rats, Wistar ; Serine Proteinase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Inhibitory effects of phenolic glycosides from Trollius chinensis Bunge on α-glucosidase: inhibition kinetics and mechanisms.
Autorzy :
Feng J; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
He F; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Huang Y; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Zhou M; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Liu X; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Ye X; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Yang R; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Tian W; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
Chen H; Fujian Provincial Key Laboratory of Innovative Drug Target, School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, People's Republic of China. .
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Źródło :
Food & function [Food Funct] 2022 Mar 07; Vol. 13 (5), pp. 2857-2864. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Ranunculaceae*
Glycoside Hydrolase Inhibitors/*pharmacology
Glycosides/*pharmacology
Phenols/*pharmacology
Plant Extracts/*pharmacology
alpha-Glucosidases/*drug effects
Flowers ; Glycoside Hydrolase Inhibitors/chemistry ; Glycosides/chemistry ; Glycosides/pharmacokinetics ; Humans ; Inhibitory Concentration 50 ; Molecular Docking Simulation ; Phenols/chemistry ; Phenols/pharmacokinetics ; Plant Extracts/chemistry ; Plant Extracts/pharmacokinetics ; alpha-Glucosidases/chemistry
Czasopismo naukowe
Tytuł :
Hypoglycemic activity of Codonopsis pilosula (Franch.) Nannf. in vitro and in vivo and its chemical composition identification by UPLC-Triple-TOF-MS/MS.
Autorzy :
Jia W; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .; University of Chinese Academy of Sciences, Beijing, China.
Bi Q; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .; University of Chinese Academy of Sciences, Beijing, China.
Jiang S; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .; University of Chinese Academy of Sciences, Beijing, China.
Tao J; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .
Liu L; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .
Yue H; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .
Zhao X; Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences, Qinghai 810008, China. .
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Źródło :
Food & function [Food Funct] 2022 Mar 07; Vol. 13 (5), pp. 2456-2464. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Codonopsis*
Diabetes Mellitus, Experimental/*prevention & control
Drugs, Chinese Herbal/*pharmacology
Hypoglycemic Agents/*pharmacology
Plant Extracts/*pharmacology
Alloxan ; Animals ; Animals, Outbred Strains ; Chromatography, High Pressure Liquid ; Drugs, Chinese Herbal/chemistry ; Glucosidases/drug effects ; Hypoglycemic Agents/chemistry ; Inhibitory Concentration 50 ; Male ; Mice ; Phytotherapy ; Plant Extracts/chemistry ; Plant Roots
SCR Organism :
Kunming mice
Czasopismo naukowe
Tytuł :
New anti-influenza A viral norsesquiterpenoids isolated from feces-residing Streptomyces sp.
Autorzy :
Lu S; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China; Department of Pharmacy, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi, People's Republic of China.
Xie X; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Hu J; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Lin H; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Li F; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Zhou R; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Guo J; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China.
Wu S; Yunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming 650091, People's Republic of China.
He J; Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, People's Republic of China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105107. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*isolation & purification
Feces/*microbiology
Influenza A virus/*drug effects
Sesquiterpenes/*isolation & purification
Streptomyces/*chemistry
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Antiviral Agents/toxicity ; Chick Embryo ; Circular Dichroism ; Crystallography, X-Ray ; Dogs ; Inhibitory Concentration 50 ; Madin Darby Canine Kidney Cells ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Sesquiterpenes/chemistry ; Sesquiterpenes/pharmacology ; Sesquiterpenes/toxicity ; Ursidae
Czasopismo naukowe
Tytuł :
Identification of limonoids from Walsura yunnanensis and evaluation of their cytotoxicity against cancer cell lines.
Autorzy :
Zhao Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Yang X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China.
Fei J; Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University, Kunming 650118, PR China.
Dong X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China.
Wang Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China; School of Life Sciences, Yunnan University, Kunming 650091, PR China.
Yang S; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China.
Hao X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China. Electronic address: .
Ding X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China. Electronic address: .
Zhao Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105120. Date of Electronic Publication: 2021 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Limonins/*toxicity
Meliaceae/*chemistry
Apoptosis ; Cell Line, Tumor ; Chromatography, High Pressure Liquid ; Chromatography, Thin Layer ; Flow Cytometry ; Humans ; Inhibitory Concentration 50 ; Limonins/chemistry ; Limonins/isolation & purification ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Molecular Structure ; Optical Rotation ; Plant Leaves/chemistry ; Plant Stems/chemistry ; Spectrophotometry, Infrared ; Wound Healing/drug effects
Czasopismo naukowe
Tytuł :
Bioactive lipids from the fruits of Solanum xanthocarpum and their anti-inflammatory activities.
Autorzy :
Xu ZP; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Algradi AM; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Liu Y; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Wang SY; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Jiang YK; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Guan W; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Pan J; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Kuang HX; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China. Electronic address: .
Yang BY; Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105134. Date of Electronic Publication: 2022 Jan 24.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Fruit/*chemistry
Lipids/*pharmacology
Phytochemicals/*pharmacology
Solanum/*chemistry
Animals ; Anti-Inflammatory Agents/chemistry ; Gas Chromatography-Mass Spectrometry ; Hydrolysis ; Inhibitory Concentration 50 ; Lipids/chemistry ; Magnetic Resonance Spectroscopy ; Mice ; Molecular Docking Simulation ; Molecular Structure ; Oxylipins/chemistry ; Oxylipins/pharmacology ; Phenols/chemistry ; Phenols/pharmacology ; Phytochemicals/chemistry ; RAW 264.7 Cells ; Sphingolipids/chemistry ; Sphingolipids/pharmacology ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Anti-inflammatory sesquiterpenoids from the heartwood of Juniperus formosana Hayata.
Autorzy :
Liu S; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Zhang J; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
He F; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Fu W; Hainan Health Management College, Chengmai 571900, China.
Tang B; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Bin Y; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Fang M; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Wu Z; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China.
Qiu Y; School of Pharmaceutical Sciences and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, South Xiang-An Road, Xiamen 361102, China. Electronic address: .
Pokaż więcej
Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105105. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*isolation & purification
Juniperus/*chemistry
Sesquiterpenes/*isolation & purification
Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Blotting, Western ; Chromatography, Thin Layer ; Inhibitory Concentration 50 ; Magnetic Resonance Spectroscopy ; Optical Rotation ; Sesquiterpenes/chemistry ; Sesquiterpenes/pharmacology ; Spectrometry, Mass, Electrospray Ionization ; Spectrophotometry, Infrared ; Wood/chemistry
Czasopismo naukowe
Tytuł :
Erianin suppresses proliferation and migration of cancer cells in a pyruvate carboxylase-dependent manner.
Autorzy :
Hong J; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Xie Z; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Yang F; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Jiang L; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Jian T; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Wang S; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China.
Guo Y; Medical Research Center, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan 610031, China.
Huang X; School of Life Science and Engineering, Southwest Jiaotong University, No. 111 North 1st Section, 2nd Ring Road, Chengdu, Sichuan 610031, China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105136. Date of Electronic Publication: 2022 Jan 31.
Typ publikacji :
Journal Article
MeSH Terms :
Bibenzyls/*pharmacology
Cell Movement/*drug effects
Cell Proliferation/*drug effects
Dendrobium/*chemistry
Phenol/*pharmacology
Pyruvate Carboxylase/*metabolism
Blotting, Western ; Cell Line, Tumor ; Computational Biology ; Fluorescent Antibody Technique ; Gas Chromatography-Mass Spectrometry ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; HEK293 Cells ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Magnetic Resonance Spectroscopy ; Molecular Docking Simulation ; Plant Extracts/pharmacology ; Pyruvate Carboxylase/antagonists & inhibitors ; Pyruvate Carboxylase/drug effects ; Wnt Signaling Pathway/drug effects
Czasopismo naukowe
Tytuł :
Petasin is the main component responsible for the anti-adipogenic effect of Petasites japonicus.
Autorzy :
Uesugi S; Iwate Biotechnology Research Center, Kitakami, Iwate 024-0003, Japan. Electronic address: .
Hakozaki M; Iwate Biotechnology Research Center, Kitakami, Iwate 024-0003, Japan.
Kanno Y; Iwate Biotechnology Research Center, Kitakami, Iwate 024-0003, Japan.
Shiraishi A; Iwate Biotechnology Research Center, Kitakami, Iwate 024-0003, Japan.
Suzuki M; Graduate School of Arts and Sciences, Graduate Course in Biological Chemistry and Food Science, Iwate University, Morioka, Iwate 020-8550, Japan.
Kimura KI; Graduate School of Arts and Sciences, Graduate Course in Biological Chemistry and Food Science, Iwate University, Morioka, Iwate 020-8550, Japan.
Shiono Y; Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan.
Yano A; Iwate Biotechnology Research Center, Kitakami, Iwate 024-0003, Japan.
Pokaż więcej
Źródło :
Fitoterapia [Fitoterapia] 2022 Mar; Vol. 157, pp. 105130. Date of Electronic Publication: 2022 Jan 18.
Typ publikacji :
Journal Article
MeSH Terms :
Adiposity/*drug effects
Obesity/*prevention & control
Petasites/*chemistry
Sesquiterpenes/*pharmacology
3T3 Cells/drug effects ; Adipogenesis/drug effects ; Animals ; Azo Compounds ; Blotting, Western ; Coloring Agents ; Flowers/chemistry ; Inhibitory Concentration 50 ; Japan ; Mice ; Polyphenols/analysis ; Pyrrolizidine Alkaloids/chemistry ; Real-Time Polymerase Chain Reaction ; Sesquiterpenes/chemistry ; Sesquiterpenes/isolation & purification ; Structure-Activity Relationship
Czasopismo naukowe

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